TEKT5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule catabolic process (GO:0016998)9.61951644
2cell wall macromolecule metabolic process (GO:0044036)9.61951644
3cilium or flagellum-dependent cell motility (GO:0001539)9.32212366
4acrosome assembly (GO:0001675)9.13119734
5sperm-egg recognition (GO:0035036)9.06004780
6axonemal dynein complex assembly (GO:0070286)8.70970294
7epithelial cilium movement (GO:0003351)8.63932781
8multicellular organism reproduction (GO:0032504)8.59447963
9plasma membrane fusion (GO:0045026)8.54068831
10binding of sperm to zona pellucida (GO:0007339)8.20133259
11response to pheromone (GO:0019236)8.14476513
12cell-cell recognition (GO:0009988)8.09508648
13motile cilium assembly (GO:0044458)7.91141779
14single strand break repair (GO:0000012)7.75843603
15spermatid development (GO:0007286)7.69432221
16regulation of cilium movement (GO:0003352)7.64478974
17cilium movement (GO:0003341)7.38356637
18reproduction (GO:0000003)7.17040678
19rRNA methylation (GO:0031167)7.05169416
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.93619534
21protein targeting to Golgi (GO:0000042)6.89181864
22establishment of protein localization to Golgi (GO:0072600)6.61721369
23piRNA metabolic process (GO:0034587)6.46261387
24retrograde transport, vesicle recycling within Golgi (GO:0000301)6.43327421
25centriole replication (GO:0007099)6.34498268
26sexual reproduction (GO:0019953)6.31155573
27sperm capacitation (GO:0048240)6.10273355
28phosphatidylethanolamine biosynthetic process (GO:0006646)6.07136652
29negative regulation of inclusion body assembly (GO:0090084)6.01216731
30calcium ion-dependent exocytosis (GO:0017156)5.90953461
31rRNA modification (GO:0000154)5.89315450
32single fertilization (GO:0007338)5.89180553
33male meiosis (GO:0007140)5.86669327
34synaptonemal complex organization (GO:0070193)5.79339636
35phosphatidylethanolamine metabolic process (GO:0046337)5.63554421
36cellular ketone body metabolic process (GO:0046950)5.49426182
37centriole assembly (GO:0098534)5.48172579
38synaptonemal complex assembly (GO:0007130)5.40750211
39spermatogenesis (GO:0007283)5.13134427
40male gamete generation (GO:0048232)5.11150592
41regulation of microtubule-based movement (GO:0060632)5.07515920
42regulation of inclusion body assembly (GO:0090083)5.06574070
43RNA destabilization (GO:0050779)5.03905681
44ventricular system development (GO:0021591)5.00735439
45fertilization (GO:0009566)4.96895176
46microtubule depolymerization (GO:0007019)4.95046082
47positive regulation of Rab GTPase activity (GO:0032851)4.89755888
48regulation of Rab GTPase activity (GO:0032313)4.89755888
49protein localization to Golgi apparatus (GO:0034067)4.88021543
50organic cation transport (GO:0015695)4.85087114
51ketone body metabolic process (GO:1902224)4.81998134
52gamete generation (GO:0007276)4.69158668
53regulation of centriole replication (GO:0046599)4.62143957
54cell recognition (GO:0008037)4.61504436
55protein localization to cilium (GO:0061512)4.35747869
56antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.33969716
57chromatin silencing (GO:0006342)4.31035186
58cellular process involved in reproduction in multicellular organism (GO:0022412)4.26075407
59germ cell development (GO:0007281)4.24322015
60nucleus organization (GO:0006997)4.10964955
61microtubule severing (GO:0051013)4.09347127
62regulation of transcription involved in cell fate commitment (GO:0060850)4.03734104
63DNA methylation involved in gamete generation (GO:0043046)4.00788369
64left/right pattern formation (GO:0060972)3.98156860
65protein polyglutamylation (GO:0018095)3.80916744
66male meiosis I (GO:0007141)3.79482339
67multicellular organismal reproductive process (GO:0048609)3.71840333
68coenzyme catabolic process (GO:0009109)3.66100713
69musculoskeletal movement (GO:0050881)3.62203586
70multicellular organismal movement (GO:0050879)3.62203586
71cellular response to pH (GO:0071467)3.57042587
72spermatid nucleus differentiation (GO:0007289)3.49709032
73intraciliary transport (GO:0042073)3.42226253
74polyol catabolic process (GO:0046174)3.39463098
75chromosome organization involved in meiosis (GO:0070192)3.39131962
76glomerular visceral epithelial cell development (GO:0072015)3.37825694
77peptidyl-threonine dephosphorylation (GO:0035970)3.36730515
78seminiferous tubule development (GO:0072520)3.35180404
79negative regulation of organelle assembly (GO:1902116)3.33699560
80glomerular epithelial cell development (GO:0072310)3.32845026
81cerebral cortex neuron differentiation (GO:0021895)3.29796296
82polyamine biosynthetic process (GO:0006596)3.29236777
83meiotic nuclear division (GO:0007126)3.27753210
84membrane depolarization during action potential (GO:0086010)3.25181729
85negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.23464356
86microtubule-based movement (GO:0007018)3.19967104
87microtubule nucleation (GO:0007020)3.16710381
88glycerol ether metabolic process (GO:0006662)3.15879812
89histone H3-K9 demethylation (GO:0033169)3.15859832
90membrane protein intracellular domain proteolysis (GO:0031293)3.15787270
91negative regulation of Rho protein signal transduction (GO:0035024)3.14248434
92regulation of interleukin-13 production (GO:0032656)3.13433086
93lactate metabolic process (GO:0006089)3.10064862
94axoneme assembly (GO:0035082)3.07650503
95energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.07074226
96ATP hydrolysis coupled proton transport (GO:0015991)3.07074226
97positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.05117514
98regulation of short-term neuronal synaptic plasticity (GO:0048172)3.02837428
99meiosis I (GO:0007127)3.00429270
100regulation of female gonad development (GO:2000194)2.99707249
101protein depolymerization (GO:0051261)2.99671265
102multicellular organismal development (GO:0007275)2.97231347
103cilium organization (GO:0044782)2.94596125
104negative regulation of histone methylation (GO:0031061)2.93644271
105glycolytic process (GO:0006096)2.92813229
106cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.92722131
107nucleosome disassembly (GO:0006337)2.92361383
108protein-DNA complex disassembly (GO:0032986)2.92361383
109protein refolding (GO:0042026)2.92197921
110cilium assembly (GO:0042384)2.91460359
111ether metabolic process (GO:0018904)2.91373587
112cranial nerve morphogenesis (GO:0021602)2.90525108
113negative regulation of gene expression, epigenetic (GO:0045814)2.89929060
114synaptic vesicle exocytosis (GO:0016079)2.87337867
115chaperone-mediated protein complex assembly (GO:0051131)2.86107976
116positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.84988252
117calcium ion import (GO:0070509)2.84470482
118homeostasis of number of cells within a tissue (GO:0048873)2.83950743
119DNA conformation change (GO:0071103)2.82760532
120positive regulation of skeletal muscle tissue development (GO:0048643)2.82155597
121vocalization behavior (GO:0071625)2.81876441
122positive regulation of endothelial cell differentiation (GO:0045603)2.78668288
123mesenchymal cell differentiation involved in kidney development (GO:0072161)2.76172028
124cellular component assembly involved in morphogenesis (GO:0010927)2.72299145
125protein K11-linked deubiquitination (GO:0035871)2.71898857
126regulation of protein kinase A signaling (GO:0010738)2.71698924
127protein localization to synapse (GO:0035418)2.71648391
128regulation of synaptic vesicle exocytosis (GO:2000300)2.67635593
129cilium morphogenesis (GO:0060271)2.67620613
130regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.67450012
131microtubule polymerization or depolymerization (GO:0031109)2.65269999
132nucleoside diphosphate phosphorylation (GO:0006165)2.63616259
133chromosome condensation (GO:0030261)2.61732514
134carnitine transport (GO:0015879)2.61488834
135amino-acid betaine transport (GO:0015838)2.61488834
136DNA packaging (GO:0006323)2.60455214
137neuron cell-cell adhesion (GO:0007158)2.60043826
138regulation of glutamate receptor signaling pathway (GO:1900449)2.57553239
139carnitine transmembrane transport (GO:1902603)2.56489013
140synaptic vesicle maturation (GO:0016188)2.54049030
141glutamate secretion (GO:0014047)2.53054026
142negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.50530609
143alditol metabolic process (GO:0019400)2.49580626
144sequestering of actin monomers (GO:0042989)2.48525420
145synaptic vesicle docking involved in exocytosis (GO:0016081)2.48293510
146ionotropic glutamate receptor signaling pathway (GO:0035235)2.43490481
147meiotic cell cycle (GO:0051321)2.42068571
148response to acidic pH (GO:0010447)2.40920863
149sperm motility (GO:0030317)11.0153440
150fusion of sperm to egg plasma membrane (GO:0007342)10.6086857
151acrosome reaction (GO:0007340)10.2444277

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.25883067
2EZH2_22144423_ChIP-Seq_EOC_Human6.10575422
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.56640558
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.33953838
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.78772226
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.92116040
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.66591537
8REST_21632747_ChIP-Seq_MESCs_Mouse2.46131114
9ZNF274_21170338_ChIP-Seq_K562_Hela2.30216717
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.20231302
11NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.18872832
12VDR_22108803_ChIP-Seq_LS180_Human2.16071408
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.11166807
14VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.06536713
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.97980448
16ERA_21632823_ChIP-Seq_H3396_Human1.96992709
17STAT6_21828071_ChIP-Seq_BEAS2B_Human1.93131010
18ELF1_20517297_ChIP-Seq_JURKAT_Human1.93021022
19GBX2_23144817_ChIP-Seq_PC3_Human1.90847625
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.89466435
21RAC3_21632823_ChIP-Seq_H3396_Human1.89153188
22EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.85568144
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85494691
24* NANOG_20526341_ChIP-Seq_ESCs_Human1.82061136
25EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.78453931
26RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.77159200
27CBX2_27304074_Chip-Seq_ESCs_Mouse1.76282404
28GATA1_26923725_Chip-Seq_HPCs_Mouse1.76137879
29TAF2_19829295_ChIP-Seq_ESCs_Human1.68199274
30EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.67678383
31* ARNT_22903824_ChIP-Seq_MCF-7_Human1.66317167
32TAF15_26573619_Chip-Seq_HEK293_Human1.65280231
33BCL6_27268052_Chip-Seq_Bcells_Human1.61193133
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.60412143
35KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.59710500
36YY1_22570637_ChIP-Seq_MALME-3M_Human1.59392322
37AUTS2_25519132_ChIP-Seq_293T-REX_Human1.59119949
38CTCF_27219007_Chip-Seq_Bcells_Human1.58543422
39TP63_19390658_ChIP-ChIP_HaCaT_Human1.57543617
40MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.57385191
41REST_18959480_ChIP-ChIP_MESCs_Mouse1.56462517
42SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.56241545
43ELK4_26923725_Chip-Seq_MESODERM_Mouse1.56138728
44* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.55636550
45MYC_19829295_ChIP-Seq_ESCs_Human1.54954570
46E2F1_20622854_ChIP-Seq_HELA_Human1.54110124
47OCT4_20526341_ChIP-Seq_ESCs_Human1.52353036
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50424306
49BCOR_27268052_Chip-Seq_Bcells_Human1.49293180
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.47186808
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.46897043
52P68_20966046_ChIP-Seq_HELA_Human1.46716905
53TDRD3_21172665_ChIP-Seq_MCF-7_Human1.46034690
54CTCF_20526341_ChIP-Seq_ESCs_Human1.46018942
55HNFA_21074721_ChIP-Seq_CACO-2_Human1.45955135
56CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.45912980
57ERG_20517297_ChIP-Seq_VCAP_Human1.44754627
58RBPJ_21746931_ChIP-Seq_IB4_Human1.43960461
59SMC4_20622854_ChIP-Seq_HELA_Human1.43346035
60PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.42619259
61CBX2_22325352_ChIP-Seq_293T-Rex_Human1.41005564
62TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.40312992
63EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.40256658
64EZH2_27294783_Chip-Seq_ESCs_Mouse1.39751180
65RNF2_27304074_Chip-Seq_NSC_Mouse1.39515645
66SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.39273891
67ETV1_20927104_ChIP-Seq_GIST48_Human1.39025306
68* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36937282
69* CBP_20019798_ChIP-Seq_JUKART_Human1.36937282
70ETV2_25802403_ChIP-Seq_MESCs_Mouse1.36805539
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36605592
72KDM2B_26808549_Chip-Seq_REH_Human1.36404331
73DROSHA_22980978_ChIP-Seq_HELA_Human1.35709412
74PHF8_20622854_ChIP-Seq_HELA_Human1.34506117
75RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.34415046
76* TP63_22573176_ChIP-Seq_HFKS_Human1.34303362
77WDR5_24793694_ChIP-Seq_LNCAP_Human1.33988871
78* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.31963803
79NFYB_21822215_ChIP-Seq_K562_Human1.31900619
80SMAD4_21799915_ChIP-Seq_A2780_Human1.31619536
81TP53_18474530_ChIP-ChIP_U2OS_Human1.31330855
82CEBPB_22108803_ChIP-Seq_LS180_Human1.30861311
83* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.28930026
84TBL1_22424771_ChIP-Seq_293T_Human1.28876341
85GATA3_21878914_ChIP-Seq_MCF-7_Human1.27376454
86TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27243067
87RARB_27405468_Chip-Seq_BRAIN_Mouse1.27127776
88P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.26468313
89PHF8_20622853_ChIP-Seq_HELA_Human1.25528601
90* P300_27268052_Chip-Seq_Bcells_Human1.25199395
91MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25021550
92SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.24558063
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23794452
94SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21586746
95GATA6_21074721_ChIP-Seq_CACO-2_Human1.21075246
96SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.19711471
97FLI1_21867929_ChIP-Seq_TH2_Mouse1.19689528
98TAL1_26923725_Chip-Seq_HPCs_Mouse1.19622183
99MTF2_20144788_ChIP-Seq_MESCs_Mouse1.19278546
100GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.18999418
101FUS_26573619_Chip-Seq_HEK293_Human1.18115488
102RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.17457436
103NANOG_18555785_Chip-Seq_ESCs_Mouse1.16316371
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15745111
105TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15745111
106P53_21459846_ChIP-Seq_SAOS-2_Human1.15381060
107STAT1_17558387_ChIP-Seq_HELA_Human1.14856200
108SOX2_19829295_ChIP-Seq_ESCs_Human1.12869130
109NANOG_19829295_ChIP-Seq_ESCs_Human1.12869130
110NFE2_27457419_Chip-Seq_LIVER_Mouse1.12633051
111* SMRT_27268052_Chip-Seq_Bcells_Human1.11910888
112IKZF1_21737484_ChIP-ChIP_HCT116_Human1.11789304
113HOXB7_26014856_ChIP-Seq_BT474_Human1.11419951
114GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.10867973
115LXR_22292898_ChIP-Seq_THP-1_Human1.09733956
116RNF2_27304074_Chip-Seq_ESCs_Mouse1.09071659
117SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09060787
118* RUNX2_22187159_ChIP-Seq_PCA_Human1.08805612
119NFYA_21822215_ChIP-Seq_K562_Human1.08267108
120SMAD4_21741376_ChIP-Seq_HESCs_Human1.07956453
121KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07833369
122RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.06215660
123RUNX_20019798_ChIP-Seq_JUKART_Human1.05924511
124SMAD3_21741376_ChIP-Seq_ESCs_Human1.05124335
125SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.04797164
126EZH2_27304074_Chip-Seq_ESCs_Mouse1.04200050
127PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.03676823
128OCT1_27270436_Chip-Seq_PROSTATE_Human1.02199078
129FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01944384
130CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.01637017
131P53_22387025_ChIP-Seq_ESCs_Mouse1.01536838
132SA1_27219007_Chip-Seq_Bcells_Human1.01416328
133AR_25329375_ChIP-Seq_VCAP_Human1.01320820
134CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.01025030
135SALL4_22934838_ChIP-ChIP_CD34+_Human1.00898669
136* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.99219374
137FOXH1_21741376_ChIP-Seq_EPCs_Human0.98838894
138SOX2_22085726_ChIP-Seq_NPCs_Mouse0.98735459
139* TCF4_23295773_ChIP-Seq_U87_Human0.98453872
140EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97574742
141SMAD3_21741376_ChIP-Seq_EPCs_Human0.97516178
142TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97495344
143* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97376684
144SOX9_26525672_Chip-Seq_HEART_Mouse0.96959695
145* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96699466
146ER_23166858_ChIP-Seq_MCF-7_Human0.96312422
147P300_19829295_ChIP-Seq_ESCs_Human0.94920992
148LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.94196082
149SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.93618051
150CMYC_18555785_Chip-Seq_ESCs_Mouse0.93251526
151RUNX1_26923725_Chip-Seq_HPCs_Mouse0.92703929
152GF1_26923725_Chip-Seq_HPCs_Mouse0.92074358
153GATA3_21867929_ChIP-Seq_TH1_Mouse0.91192053
154PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90395821
155CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90070797
156MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89924453
157SMAD4_21741376_ChIP-Seq_EPCs_Human0.89257673
158MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.88715421
159EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.88136954
160GATA3_21867929_ChIP-Seq_CD8_Mouse0.88128667
161CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.87448017
162TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.87354262
163P300_18555785_Chip-Seq_ESCs_Mouse0.87169437
164FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87054958
165PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.86822124
166OCT4_18555785_Chip-Seq_ESCs_Mouse0.86637813
167CRX_20693478_ChIP-Seq_RETINA_Mouse0.86444228

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.69088076
2MP0003878_abnormal_ear_physiology4.69088076
3MP0003698_abnormal_male_reproductive4.28199574
4MP0001929_abnormal_gametogenesis3.61468372
5MP0003880_abnormal_central_pattern3.61383289
6MP0008877_abnormal_DNA_methylation3.47834791
7MP0001348_abnormal_lacrimal_gland3.43794592
8MP0004859_abnormal_synaptic_plasticity3.24832348
9MP0003718_maternal_effect3.20566614
10MP0009046_muscle_twitch2.82732995
11MP0003635_abnormal_synaptic_transmissio2.59233902
12MP0002653_abnormal_ependyma_morphology2.59186646
13MP0001968_abnormal_touch/_nociception2.48402460
14MP0004270_analgesia2.42398021
15MP0002736_abnormal_nociception_after2.37544456
16MP0000678_abnormal_parathyroid_gland2.35116342
17MP0002161_abnormal_fertility/fecundity2.32149383
18MP0000566_synostosis2.14186448
19MP0002210_abnormal_sex_determination2.13009349
20MP0002132_abnormal_respiratory_system2.13002934
21MP0009745_abnormal_behavioral_response2.12897610
22MP0005423_abnormal_somatic_nervous2.09876339
23MP0002063_abnormal_learning/memory/cond2.08737459
24MP0002822_catalepsy2.04333958
25MP0002064_seizures2.00526312
26MP0005410_abnormal_fertilization11.2311912
27MP0003011_delayed_dark_adaptation1.95099048
28MP0002572_abnormal_emotion/affect_behav1.94815459
29MP0001984_abnormal_olfaction1.92173982
30MP0003283_abnormal_digestive_organ1.87717343
31MP0001986_abnormal_taste_sensitivity1.87684691
32MP0001145_abnormal_male_reproductive1.81111906
33MP0003787_abnormal_imprinting1.79554065
34MP0002272_abnormal_nervous_system1.73960248
35MP0002734_abnormal_mechanical_nocicepti1.68277767
36MP0005623_abnormal_meninges_morphology1.61705783
37MP0002138_abnormal_hepatobiliary_system1.61577765
38MP0001486_abnormal_startle_reflex1.60277626
39MP0000653_abnormal_sex_gland1.59682875
40MP0008995_early_reproductive_senescence1.57942541
41MP0005310_abnormal_salivary_gland1.57420692
42MP0005379_endocrine/exocrine_gland_phen1.56701712
43MP0001440_abnormal_grooming_behavior1.56392860
44MP0003646_muscle_fatigue1.55908222
45MP0002249_abnormal_larynx_morphology1.54266721
46MP0009053_abnormal_anal_canal1.46325372
47MP0005395_other_phenotype1.41282566
48MP0004233_abnormal_muscle_weight1.38282604
49MP0002160_abnormal_reproductive_system1.36973296
50MP0002733_abnormal_thermal_nociception1.36380705
51MP0002067_abnormal_sensory_capabilities1.33911055
52MP0001485_abnormal_pinna_reflex1.33089018
53MP0002735_abnormal_chemical_nociception1.31407003
54MP0004811_abnormal_neuron_physiology1.30194655
55MP0003329_amyloid_beta_deposits1.28186941
56MP0003879_abnormal_hair_cell1.27661524
57MP0005451_abnormal_body_composition1.27214431
58MP0006276_abnormal_autonomic_nervous1.22543928
59MP0001501_abnormal_sleep_pattern1.20093812
60MP0002557_abnormal_social/conspecific_i1.18152384
61MP0004510_myositis1.17177912
62MP0002127_abnormal_cardiovascular_syste1.13079400
63MP0001970_abnormal_pain_threshold1.12863403
64MP0001529_abnormal_vocalization1.12736028
65MP0008569_lethality_at_weaning1.12132044
66MP0008789_abnormal_olfactory_epithelium1.06123369
67MP0005248_abnormal_Harderian_gland1.05932809
68MP0000026_abnormal_inner_ear1.03000135
69MP0000778_abnormal_nervous_system1.02020738
70MP0000751_myopathy1.01086409
71MP0000955_abnormal_spinal_cord1.01035238
72MP0002184_abnormal_innervation0.99881265
73MP0003122_maternal_imprinting0.99699428
74MP0008004_abnormal_stomach_pH0.98697819
75MP0004142_abnormal_muscle_tone0.98606409
76MP0005386_behavior/neurological_phenoty0.98560309
77MP0004924_abnormal_behavior0.98560309
78MP0005645_abnormal_hypothalamus_physiol0.97921780
79MP0002909_abnormal_adrenal_gland0.96910050
80MP0000681_abnormal_thyroid_gland0.95412727
81MP0002066_abnormal_motor_capabilities/c0.93618805
82MP0002882_abnormal_neuron_morphology0.91937380
83MP0001765_abnormal_ion_homeostasis0.88794510
84MP0002282_abnormal_trachea_morphology0.88177221
85MP0003633_abnormal_nervous_system0.86793638
86MP0008961_abnormal_basal_metabolism0.85890526
87MP0005670_abnormal_white_adipose0.85369485
88MP0005646_abnormal_pituitary_gland0.84876160
89MP0002152_abnormal_brain_morphology0.84658388
90MP0001905_abnormal_dopamine_level0.82390285
91MP0004742_abnormal_vestibular_system0.79008377
92MP0003699_abnormal_female_reproductive0.78689303
93MP0002234_abnormal_pharynx_morphology0.77831624
94MP0000534_abnormal_ureter_morphology0.77387138
95MP0000049_abnormal_middle_ear0.73463742
96MP0003631_nervous_system_phenotype0.72893707
97MP0005647_abnormal_sex_gland0.72226602
98MP0001502_abnormal_circadian_rhythm0.71964031
99MP0009115_abnormal_fat_cell0.70958890
100MP0004858_abnormal_nervous_system0.70868764
101MP0002254_reproductive_system_inflammat0.70771081
102MP0005551_abnormal_eye_electrophysiolog0.69275305
103MP0003119_abnormal_digestive_system0.64386866
104MP0002229_neurodegeneration0.63951701
105MP0002069_abnormal_eating/drinking_beha0.63936748
106MP0003077_abnormal_cell_cycle0.63729891
107MP0009780_abnormal_chondrocyte_physiolo0.63342421
108MP0000516_abnormal_urinary_system0.62816759
109MP0005367_renal/urinary_system_phenotyp0.62816759
110MP0006292_abnormal_olfactory_placode0.62121828
111MP0004145_abnormal_muscle_electrophysio0.60804846
112MP0005167_abnormal_blood-brain_barrier0.60375096
113MP0004885_abnormal_endolymph0.59465616
114MP0000013_abnormal_adipose_tissue0.58298120
115MP0008872_abnormal_physiological_respon0.58296202
116MP0006072_abnormal_retinal_apoptosis0.56781276
117MP0001963_abnormal_hearing_physiology0.56717698
118MP0002837_dystrophic_cardiac_calcinosis0.56439223
119MP0002752_abnormal_somatic_nervous0.56312457
120MP0001119_abnormal_female_reproductive0.56255623
121MP0005389_reproductive_system_phenotype0.55573342
122MP0005636_abnormal_mineral_homeostasis0.55006534
123MP0001666_abnormal_nutrient_absorption0.54528286
124MP0005083_abnormal_biliary_tract0.53984050
125MP0005408_hypopigmentation0.53805149
126MP0004036_abnormal_muscle_relaxation0.52373771
127MP0003861_abnormal_nervous_system0.52361834
128MP0001664_abnormal_digestion0.52184114
129MP0004085_abnormal_heartbeat0.51643946
130MP0005499_abnormal_olfactory_system0.51577730
131MP0005394_taste/olfaction_phenotype0.51577730
132MP0002876_abnormal_thyroid_physiology0.51316008
133MP0001943_abnormal_respiration0.50552236
134MP0000470_abnormal_stomach_morphology0.50035962
135MP0009697_abnormal_copulation0.49625839
136MP0010307_abnormal_tumor_latency0.49494214
137MP0004133_heterotaxia0.49409949
138MP0004043_abnormal_pH_regulation0.49186029
139MP0001879_abnormal_lymphatic_vessel0.48859796
140MP0005535_abnormal_body_temperature0.48602994
141MP0005253_abnormal_eye_physiology0.48385451
142MP0000003_abnormal_adipose_tissue0.48074619
143MP0005375_adipose_tissue_phenotype0.47812872
144MP0000569_abnormal_digit_pigmentation0.46697483
145MP0003634_abnormal_glial_cell0.46625602
146MP0003121_genomic_imprinting0.46623135
147MP0003115_abnormal_respiratory_system0.46200865
148MP0005666_abnormal_adipose_tissue0.46125248
149MP0003137_abnormal_impulse_conducting0.45285334
150MP0000613_abnormal_salivary_gland0.41949950
151MP0003936_abnormal_reproductive_system0.41080638
152MP0001270_distended_abdomen0.34017889
153MP0001764_abnormal_homeostasis0.32781545
154MP0001293_anophthalmia0.31379209

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.20223622
2Abnormal respiratory motile cilium morphology (HP:0005938)8.12299280
3Abnormal respiratory epithelium morphology (HP:0012253)8.12299280
4Severe visual impairment (HP:0001141)7.37629653
5Abnormal ciliary motility (HP:0012262)6.80962126
6Rhinitis (HP:0012384)6.72272916
7Chronic bronchitis (HP:0004469)6.12591626
8Infertility (HP:0000789)5.83589031
9Attenuation of retinal blood vessels (HP:0007843)4.96418441
10Bony spicule pigmentary retinopathy (HP:0007737)4.89802864
11Asymmetric septal hypertrophy (HP:0001670)4.87616157
12Nasal polyposis (HP:0100582)4.62149074
13Chronic hepatic failure (HP:0100626)4.57222602
14Abnormal rod and cone electroretinograms (HP:0008323)4.14466402
15Hypoplastic ischia (HP:0003175)4.12228825
16Abnormality of macular pigmentation (HP:0008002)4.07854997
17Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.04481633
18Cone-rod dystrophy (HP:0000548)3.96189701
19Nephronophthisis (HP:0000090)3.95015104
20Hyperkalemia (HP:0002153)3.90798632
21Resting tremor (HP:0002322)3.80510590
22Bell-shaped thorax (HP:0001591)3.77877491
23Abnormality of the nasal mucosa (HP:0000433)3.66245014
24Bronchitis (HP:0012387)3.64117163
25Bronchiectasis (HP:0002110)3.63719464
26Abnormality of the ischium (HP:0003174)3.60962161
27Facial shape deformation (HP:0011334)3.44280681
28Potter facies (HP:0002009)3.44280681
29Enlarged epiphyses (HP:0010580)3.42535961
30Focal motor seizures (HP:0011153)3.38039982
31Aplasia/Hypoplasia of the earlobes (HP:0009906)3.36807345
32Male infertility (HP:0003251)3.34728616
33Progressive sensorineural hearing impairment (HP:0000408)3.30073838
34Medial flaring of the eyebrow (HP:0010747)3.27500224
35Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.14135942
36Amelogenesis imperfecta (HP:0000705)2.99351798
37Abnormality of the renal medulla (HP:0100957)2.89800822
38Generalized aminoaciduria (HP:0002909)2.86216323
39Abnormality of dental color (HP:0011073)2.86208322
40Abnormality of the lower motor neuron (HP:0002366)2.84334452
41Hypoplasia of the thymus (HP:0000778)2.75769325
42Truncal obesity (HP:0001956)2.69822590
43Gait imbalance (HP:0002141)2.58458218
44Abnormal urine output (HP:0012590)2.56961275
45Hypoalphalipoproteinemia (HP:0003233)2.53851979
46Molar tooth sign on MRI (HP:0002419)2.53310632
47Abnormality of midbrain morphology (HP:0002418)2.53310632
48Myokymia (HP:0002411)2.53297250
49Visual hallucinations (HP:0002367)2.49381445
50Tubulointerstitial nephritis (HP:0001970)2.48644432
51Progressive cerebellar ataxia (HP:0002073)2.47427635
52Cholecystitis (HP:0001082)2.46623012
53Abnormal gallbladder physiology (HP:0012438)2.46623012
54Recurrent otitis media (HP:0000403)2.42658459
55Menstrual irregularities (HP:0000858)2.38403082
56Congenital primary aphakia (HP:0007707)2.38181327
57Unilateral renal agenesis (HP:0000122)2.37522621
58Abnormal spermatogenesis (HP:0008669)2.32711759
59Abnormality of the pubic bones (HP:0003172)2.31286621
60Renovascular hypertension (HP:0100817)2.31269864
61Hypophosphatemic rickets (HP:0004912)2.30836570
62Focal seizures (HP:0007359)2.30384636
63Portal hypertension (HP:0001409)2.29989175
64Osteomalacia (HP:0002749)2.27736251
65Insulin-resistant diabetes mellitus (HP:0000831)2.22447604
66Abnormality of renal excretion (HP:0011036)2.21789267
67Abnormality of potassium homeostasis (HP:0011042)2.21089505
68Congenital malformation of the right heart (HP:0011723)2.19142456
69Double outlet right ventricle (HP:0001719)2.19142456
70Epileptic encephalopathy (HP:0200134)2.17427492
71Abnormality of the costochondral junction (HP:0000919)2.16560534
72Epiphyseal dysplasia (HP:0002656)2.15898623
73Recurrent sinusitis (HP:0011108)2.15442569
74Nephrogenic diabetes insipidus (HP:0009806)2.12704503
75Widely patent fontanelles and sutures (HP:0004492)2.11573558
76Abnormality of the hepatic vasculature (HP:0006707)2.10273130
77Recurrent pneumonia (HP:0006532)2.09769475
78Abnormality of the aortic arch (HP:0012303)2.07981624
79Amyotrophic lateral sclerosis (HP:0007354)2.07266784
80Focal segmental glomerulosclerosis (HP:0000097)2.05830247
81Polyuria (HP:0000103)2.05692602
82Spastic tetraparesis (HP:0001285)2.05389336
83Hemiparesis (HP:0001269)2.03778081
84Flattened epiphyses (HP:0003071)2.02908633
85Progressive hearing impairment (HP:0001730)2.00620319
86Polyphagia (HP:0002591)2.00492552
87Dynein arm defect of respiratory motile cilia (HP:0012255)11.3103793
88Absent/shortened dynein arms (HP:0200106)11.3103793
89Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.1854815
90Recurrent bronchitis (HP:0002837)1.98467520
91Absent epiphyses (HP:0010577)1.98171431
92Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.98171431
93Impulsivity (HP:0100710)1.97345022
94Optic nerve hypoplasia (HP:0000609)1.96927689
95Tubular atrophy (HP:0000092)1.96683486
96Abnormality of the epiphysis of the femoral head (HP:0010574)1.95945958
97Sensory axonal neuropathy (HP:0003390)1.95513591
98Tubulointerstitial abnormality (HP:0001969)1.94211267
99Atonic seizures (HP:0010819)1.93931151
100Intellectual disability, moderate (HP:0002342)1.91869241
101Impaired vibration sensation in the lower limbs (HP:0002166)1.91181583
102Genital tract atresia (HP:0001827)1.90098366
103Vaginal atresia (HP:0000148)1.89219386
104Supranuclear gaze palsy (HP:0000605)1.87533108
105Flat capital femoral epiphysis (HP:0003370)1.86824747
106Aplasia/Hypoplasia of the lens (HP:0008063)1.84554169
107Pendular nystagmus (HP:0012043)1.84033064
108Hyponatremia (HP:0002902)1.83871845
109Choroideremia (HP:0001139)1.82349879
110Cerebellar dysplasia (HP:0007033)1.82280935
111Anterior segment dysgenesis (HP:0007700)1.81690529
112Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.81421909
113Abnormality of femoral epiphyses (HP:0006499)1.81421909
114Photophobia (HP:0000613)1.80733355
115Ventricular tachycardia (HP:0004756)1.80282198
116Poor suck (HP:0002033)1.79485585
117Hyperventilation (HP:0002883)1.79255770
118Abnormality of lateral ventricle (HP:0030047)1.78641636
119Postaxial foot polydactyly (HP:0001830)1.77747292
120Poor coordination (HP:0002370)1.77505421
121Occipital encephalocele (HP:0002085)1.77458666
122Postaxial hand polydactyly (HP:0001162)1.76825205
123Abdominal situs inversus (HP:0003363)1.75700572
124Abnormality of abdominal situs (HP:0011620)1.75700572
125Abnormality of the parathyroid morphology (HP:0011766)1.75273401
126Neurofibrillary tangles (HP:0002185)1.74760426
127Short ribs (HP:0000773)1.74511590
128Abnormality of the femoral head (HP:0003368)1.74434575
129Gonadotropin excess (HP:0000837)1.74132807
130Decreased central vision (HP:0007663)1.72309410
131Fibular hypoplasia (HP:0003038)1.72249230
132Gaze-evoked nystagmus (HP:0000640)1.72077174
133Chronic sinusitis (HP:0011109)1.70915899
134Abnormality of ocular smooth pursuit (HP:0000617)1.70871311
135Oculomotor apraxia (HP:0000657)1.70066633
136Bundle branch block (HP:0011710)1.69296469
137Cerebral inclusion bodies (HP:0100314)1.69048119
138Abnormality of saccadic eye movements (HP:0000570)1.67897914
139Abnormal eating behavior (HP:0100738)1.66203917
140Stage 5 chronic kidney disease (HP:0003774)1.59868053
141Impaired smooth pursuit (HP:0007772)1.58301183
142Dyschromatopsia (HP:0007641)1.56708831
143True hermaphroditism (HP:0010459)1.56529625
144Tubulointerstitial fibrosis (HP:0005576)1.55435941
145Congenital hepatic fibrosis (HP:0002612)1.54222763
146Pancreatic fibrosis (HP:0100732)1.53065512
147Abnormal hair whorl (HP:0010721)1.50402507
148Progressive inability to walk (HP:0002505)1.49866979
149Postural instability (HP:0002172)1.49710906
150Specific learning disability (HP:0001328)1.49270036
151Aplasia/Hypoplasia of the brainstem (HP:0007362)1.49025168
152Hypoplasia of the brainstem (HP:0002365)1.49025168
153Ankle clonus (HP:0011448)1.45355851
154Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.45289866
155Abnormal drinking behavior (HP:0030082)1.42262448
156Polydipsia (HP:0001959)1.42262448
157Lissencephaly (HP:0001339)1.40592883
158Abnormality of the dental root (HP:0006486)1.39696392
159Taurodontia (HP:0000679)1.39696392
160Abnormality of permanent molar morphology (HP:0011071)1.39696392
161Retinal dysplasia (HP:0007973)1.39386756
162Absence seizures (HP:0002121)1.39305964
163Renal dysplasia (HP:0000110)1.38634301
164Febrile seizures (HP:0002373)1.38400596
165Azoospermia (HP:0000027)1.38105232
166Hypoplasia of the capital femoral epiphysis (HP:0003090)1.37994529
167Urinary urgency (HP:0000012)1.37613364
168Decreased electroretinogram (ERG) amplitude (HP:0000654)1.36929681
169J-shaped sella turcica (HP:0002680)1.35882536
170Amblyopia (HP:0000646)1.35796836
171Delayed gross motor development (HP:0002194)1.35435034

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK48.50062802
2PDK36.89779437
3PDK46.89779437
4TESK14.83749415
5PRKD34.48584955
6DDR24.45871455
7PDK24.38725597
8INSRR4.10442563
9ICK3.12050997
10MAP4K23.00446906
11BRD42.95482865
12PNCK2.45779362
13STK38L2.23362947
14PTK2B2.16519333
15NTRK32.08798997
16MST1R1.94511191
17STK381.86393717
18CDK121.76091046
19EPHA41.72638923
20WNK41.71801583
21PIK3CG1.64003854
22MARK11.63307529
23MAP3K91.62184433
24CDK71.52504377
25STK391.51701648
26MAP3K41.49434470
27LATS21.45252740
28NTRK21.42145935
29MINK11.39587798
30MAP2K71.39399628
31MAP3K121.32965501
32DAPK21.28697818
33CASK1.19913903
34ERBB31.12868586
35PAK61.07871963
36RIPK41.07008294
37PDK11.04401053
38DYRK1B1.02561673
39PRKCG0.99738538
40PLK20.99671866
41CDK190.96757878
42BRSK20.94680263
43TYRO30.94222565
44NME10.91446527
45GRK50.89605840
46MAPKAPK50.85798692
47WNK10.83979516
48KSR20.78722090
49DAPK10.78154112
50CAMK1D0.78137161
51KSR10.74228402
52MAP2K40.74064092
53TESK20.73713842
54CAMK2A0.72906442
55MAPK130.71407222
56MAP2K20.71250710
57PDPK10.70454968
58ARAF0.70054987
59CAMKK10.64104752
60PRKAA20.64049340
61RPS6KA10.63536857
62CDK50.62636085
63CCNB10.61171917
64PRKG10.60789175
65PINK10.60576002
66LMTK20.60187382
67BMPR1B0.58488128
68TAOK10.57845851
69MAP3K80.56118613
70CDK180.56053717
71MUSK0.56016150
72MAPK150.55380795
73UHMK10.54703663
74BMPR20.53195452
75MAP2K60.52968931
76CDK150.52055477
77MAP3K130.51735591
78GRK70.51040184
79ROCK10.50533337
80BRAF0.48142175
81CDK20.48081335
82CDK140.47564410
83SGK2230.47061879
84SGK4940.47061879
85OXSR10.46526935
86FER0.46434922
87LATS10.44877255
88MET0.43970603
89PRKG20.43953891
90FRK0.43540931
91GSK3B0.43107315
92CDK11A0.42760101
93CHUK0.41956420
94RPS6KL10.40910171
95RPS6KC10.40910171
96SGK20.40585887
97TNIK0.40322479
98CDK10.40094321
99MAPK10.39486828
100NEK60.39391443
101PAK30.39391365
102RPS6KA60.38837990
103PHKG10.38652079
104PHKG20.38652079
105MTOR0.37859607
106PRKCZ0.36284101
107IRAK20.35624196
108MAP2K10.35247669
109TLK10.34148568
110CAMK2B0.34032753
111CHEK10.32266182
112MARK20.32125690
113NEK20.31749552
114CAMK10.30692488
115CDK30.29951603
116AKT30.29858122
117NTRK10.28926768
118STK110.28919130
119WNK30.28123235
120BRSK10.28119519
121IKBKB0.28057511
122PAK10.28045263
123ZAK0.27596508
124CAMK1G0.26992914
125BCR0.26201275
126MAPK110.25626488
127MAP3K10.24952336
128MAPK80.24483445
129RAF10.23281287
130MAP3K20.22564286
131SIK30.22210815
132SGK10.21742882
133IRAK10.21512609
134ADRBK10.21362974
135AKT10.21099562
136AURKA0.20421387
137PKN10.19939355
138MAP3K110.19719323
139CAMK2G0.19408941
140CAMK40.19043372
141SIK20.19023653
142RPS6KA20.18185425
143TIE10.18116168
144MAPK140.18022586
145MAPK100.18006008
146RPS6KA30.17737859
147PRKACA0.17399062
148RPS6KB10.17220985
149PRKCB0.17162543
150PRPF4B0.16429940
151DYRK1A0.16079326
152EEF2K0.16026096
153MAPKAPK30.15908814
154SGK30.15553802
155JAK30.13427108
156PRKCI0.12813555

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000727.52514043
2Synaptic vesicle cycle_Homo sapiens_hsa047213.45435729
3Nicotine addiction_Homo sapiens_hsa050332.85331524
4Amphetamine addiction_Homo sapiens_hsa050312.67825568
5Collecting duct acid secretion_Homo sapiens_hsa049662.59399091
6Allograft rejection_Homo sapiens_hsa053302.58914252
7Vitamin B6 metabolism_Homo sapiens_hsa007502.56010477
8Autoimmune thyroid disease_Homo sapiens_hsa053202.54971276
9Butanoate metabolism_Homo sapiens_hsa006502.50620440
10Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.37162280
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.32693389
12Graft-versus-host disease_Homo sapiens_hsa053322.31397580
13Type I diabetes mellitus_Homo sapiens_hsa049402.27301520
14Long-term potentiation_Homo sapiens_hsa047202.26919657
15Phenylalanine metabolism_Homo sapiens_hsa003602.23220970
16Pyruvate metabolism_Homo sapiens_hsa006202.22306891
17Olfactory transduction_Homo sapiens_hsa047402.19127053
18Fatty acid biosynthesis_Homo sapiens_hsa000612.11833362
19Taste transduction_Homo sapiens_hsa047422.06338991
20Circadian entrainment_Homo sapiens_hsa047132.02844653
21RNA transport_Homo sapiens_hsa030131.96996591
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.96596983
23Antigen processing and presentation_Homo sapiens_hsa046121.92416750
24Insulin secretion_Homo sapiens_hsa049111.84353529
25Cardiac muscle contraction_Homo sapiens_hsa042601.83730122
26Glucagon signaling pathway_Homo sapiens_hsa049221.83158821
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.80810739
28Renin secretion_Homo sapiens_hsa049241.78030318
29Glutamatergic synapse_Homo sapiens_hsa047241.72666665
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.71617427
31Huntingtons disease_Homo sapiens_hsa050161.70720077
32Dorso-ventral axis formation_Homo sapiens_hsa043201.63168710
33Salivary secretion_Homo sapiens_hsa049701.63109013
34Morphine addiction_Homo sapiens_hsa050321.61313224
35Dopaminergic synapse_Homo sapiens_hsa047281.58542966
36Oocyte meiosis_Homo sapiens_hsa041141.57766463
37GABAergic synapse_Homo sapiens_hsa047271.57426464
38Viral myocarditis_Homo sapiens_hsa054161.57246005
39Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.55063948
40Gastric acid secretion_Homo sapiens_hsa049711.50871530
41Calcium signaling pathway_Homo sapiens_hsa040201.46274590
42Oxidative phosphorylation_Homo sapiens_hsa001901.44299973
43Cocaine addiction_Homo sapiens_hsa050301.37437865
44Fatty acid degradation_Homo sapiens_hsa000711.36529148
45Vibrio cholerae infection_Homo sapiens_hsa051101.36488306
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25915747
47alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.25129639
48Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.24416552
49Linoleic acid metabolism_Homo sapiens_hsa005911.23033693
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.16715362
51ABC transporters_Homo sapiens_hsa020101.15744518
52Alzheimers disease_Homo sapiens_hsa050101.15487204
53Parkinsons disease_Homo sapiens_hsa050121.13273359
54Influenza A_Homo sapiens_hsa051641.12976792
55Glycerophospholipid metabolism_Homo sapiens_hsa005641.12850378
56Glycerolipid metabolism_Homo sapiens_hsa005611.12162075
57Arginine and proline metabolism_Homo sapiens_hsa003301.11101347
58Aldosterone synthesis and secretion_Homo sapiens_hsa049251.06840301
59Oxytocin signaling pathway_Homo sapiens_hsa049211.05363977
60Propanoate metabolism_Homo sapiens_hsa006401.05303764
61Serotonergic synapse_Homo sapiens_hsa047261.05234125
62Estrogen signaling pathway_Homo sapiens_hsa049151.04960865
63Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04267557
64Fructose and mannose metabolism_Homo sapiens_hsa000511.01062745
65Selenocompound metabolism_Homo sapiens_hsa004501.00489110
66cAMP signaling pathway_Homo sapiens_hsa040241.00196946
67Tyrosine metabolism_Homo sapiens_hsa003500.96125777
68Intestinal immune network for IgA production_Homo sapiens_hsa046720.95242553
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94214240
70Protein digestion and absorption_Homo sapiens_hsa049740.92728078
71Long-term depression_Homo sapiens_hsa047300.91961036
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.89638093
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.88320415
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87931594
75Cholinergic synapse_Homo sapiens_hsa047250.86421239
76Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.83220595
77Gap junction_Homo sapiens_hsa045400.82763082
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.81627486
79Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80554190
80Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.78909564
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.77658339
82Adipocytokine signaling pathway_Homo sapiens_hsa049200.77441793
83Fat digestion and absorption_Homo sapiens_hsa049750.74959283
84Basal transcription factors_Homo sapiens_hsa030220.74632799
85Ether lipid metabolism_Homo sapiens_hsa005650.70247368
86Thyroid hormone synthesis_Homo sapiens_hsa049180.69811767
87Arginine biosynthesis_Homo sapiens_hsa002200.69560499
88Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69071993
89Asthma_Homo sapiens_hsa053100.69033573
90Retinol metabolism_Homo sapiens_hsa008300.66746771
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.66711733
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.62244548
93GnRH signaling pathway_Homo sapiens_hsa049120.62132282
94Type II diabetes mellitus_Homo sapiens_hsa049300.61931756
95Hedgehog signaling pathway_Homo sapiens_hsa043400.61840637
96Endocytosis_Homo sapiens_hsa041440.61798851
97Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.61618825
98Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.60843433
99Carbon metabolism_Homo sapiens_hsa012000.59666545
100Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58653821
101Axon guidance_Homo sapiens_hsa043600.58316144
102Caffeine metabolism_Homo sapiens_hsa002320.57298117
103Primary bile acid biosynthesis_Homo sapiens_hsa001200.57161988
104Pancreatic secretion_Homo sapiens_hsa049720.56977589
105Alcoholism_Homo sapiens_hsa050340.55564318
106Melanogenesis_Homo sapiens_hsa049160.55501832
107Nitrogen metabolism_Homo sapiens_hsa009100.54799411
108Inositol phosphate metabolism_Homo sapiens_hsa005620.54078288
109mRNA surveillance pathway_Homo sapiens_hsa030150.50498569
110Base excision repair_Homo sapiens_hsa034100.50388488
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.48092261
112PPAR signaling pathway_Homo sapiens_hsa033200.47643485
113Mineral absorption_Homo sapiens_hsa049780.47603649
114B cell receptor signaling pathway_Homo sapiens_hsa046620.46890143
115Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.46497815
116Herpes simplex infection_Homo sapiens_hsa051680.45921896
117Pentose phosphate pathway_Homo sapiens_hsa000300.43924220
118VEGF signaling pathway_Homo sapiens_hsa043700.43165381
119Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.41076214
120MAPK signaling pathway_Homo sapiens_hsa040100.39906534
121Phototransduction_Homo sapiens_hsa047440.39742727
122Phospholipase D signaling pathway_Homo sapiens_hsa040720.39475907
123Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39372747
124Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39052203
125Systemic lupus erythematosus_Homo sapiens_hsa053220.39027911
126Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38322964
127Viral carcinogenesis_Homo sapiens_hsa052030.37840538
128Histidine metabolism_Homo sapiens_hsa003400.36420183
129ErbB signaling pathway_Homo sapiens_hsa040120.35724505
130Rheumatoid arthritis_Homo sapiens_hsa053230.35680686
131Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35661936
132Phagosome_Homo sapiens_hsa041450.35074752
133Steroid hormone biosynthesis_Homo sapiens_hsa001400.35068460
134Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.34372425
135Choline metabolism in cancer_Homo sapiens_hsa052310.30942788
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.30926746
137Fatty acid metabolism_Homo sapiens_hsa012120.30864908
138Purine metabolism_Homo sapiens_hsa002300.30185692
139Bile secretion_Homo sapiens_hsa049760.29844709
140Biosynthesis of amino acids_Homo sapiens_hsa012300.28477002
141Chemical carcinogenesis_Homo sapiens_hsa052040.28118793
142Jak-STAT signaling pathway_Homo sapiens_hsa046300.27670723
143Tight junction_Homo sapiens_hsa045300.27670495
144Renin-angiotensin system_Homo sapiens_hsa046140.27252572
145Fanconi anemia pathway_Homo sapiens_hsa034600.25989338
146Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.24933779
147Prolactin signaling pathway_Homo sapiens_hsa049170.23073444
148Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21927429
149Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21704549

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »