TENM4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.55789459
2regulation of short-term neuronal synaptic plasticity (GO:0048172)4.64641507
3neuron cell-cell adhesion (GO:0007158)4.50270403
4vocalization behavior (GO:0071625)4.45627911
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.39998761
6dendritic spine morphogenesis (GO:0060997)4.37024930
7nucleobase catabolic process (GO:0046113)4.34608508
8axonal fasciculation (GO:0007413)4.29564002
9protein localization to synapse (GO:0035418)4.28264999
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.24481651
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.10695411
12synaptic vesicle maturation (GO:0016188)4.10649756
13synaptic vesicle exocytosis (GO:0016079)4.09464582
14locomotory exploration behavior (GO:0035641)4.07144412
15neuron recognition (GO:0008038)4.05509753
16layer formation in cerebral cortex (GO:0021819)3.93314589
17synaptic vesicle docking involved in exocytosis (GO:0016081)3.85082599
18regulation of glutamate receptor signaling pathway (GO:1900449)3.82489372
19behavioral response to nicotine (GO:0035095)3.77481196
20retinal ganglion cell axon guidance (GO:0031290)3.75414135
21glutamate secretion (GO:0014047)3.66834368
22regulation of synaptic vesicle exocytosis (GO:2000300)3.63579055
23central nervous system neuron axonogenesis (GO:0021955)3.55174700
24exploration behavior (GO:0035640)3.54772602
25limb bud formation (GO:0060174)3.54059185
26ionotropic glutamate receptor signaling pathway (GO:0035235)3.52464072
27regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.43580991
28regulation of neuronal synaptic plasticity (GO:0048168)3.42057390
29glutamate receptor signaling pathway (GO:0007215)3.41369170
30positive regulation of synapse maturation (GO:0090129)3.41094295
31spinal cord development (GO:0021510)3.37638015
32innervation (GO:0060384)3.35909061
33regulation of long-term neuronal synaptic plasticity (GO:0048169)3.34752455
34mating behavior (GO:0007617)3.32169869
35regulation of synapse structural plasticity (GO:0051823)3.27505886
36neuronal action potential propagation (GO:0019227)3.22343926
37synaptic transmission, glutamatergic (GO:0035249)3.22207886
38cell migration in hindbrain (GO:0021535)3.20662085
39regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.18416004
40proline transport (GO:0015824)3.12212648
41neurotransmitter-gated ion channel clustering (GO:0072578)3.12149661
42neurotransmitter secretion (GO:0007269)3.11042178
43establishment of nucleus localization (GO:0040023)3.10917430
44regulation of dendritic spine morphogenesis (GO:0061001)3.10139454
45neuron-neuron synaptic transmission (GO:0007270)3.09527605
46G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.09220117
47dendritic spine organization (GO:0097061)3.08658201
48synaptic vesicle endocytosis (GO:0048488)3.06971472
49regulation of synaptic vesicle transport (GO:1902803)3.06077815
50lateral sprouting from an epithelium (GO:0060601)3.05808789
51cranial nerve morphogenesis (GO:0021602)3.04309304
52auditory behavior (GO:0031223)3.04241339
53positive regulation of synaptic transmission, GABAergic (GO:0032230)3.03184027
54presynaptic membrane assembly (GO:0097105)3.02472068
55cerebellar Purkinje cell differentiation (GO:0021702)3.02336510
56negative chemotaxis (GO:0050919)3.00157891
57cerebral cortex radially oriented cell migration (GO:0021799)2.99448597
58dendrite morphogenesis (GO:0048813)2.99420399
59regulation of excitatory postsynaptic membrane potential (GO:0060079)2.97667463
60central nervous system projection neuron axonogenesis (GO:0021952)2.97005600
61regulation of postsynaptic membrane potential (GO:0060078)2.93652238
62transmission of nerve impulse (GO:0019226)2.93515027
63membrane hyperpolarization (GO:0060081)2.91932545
64positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.90540101
65short-term memory (GO:0007614)2.90009654
66membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.89902550
67regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.88867668
68neuronal ion channel clustering (GO:0045161)2.88315111
69postsynaptic membrane organization (GO:0001941)2.87953381
70synapse assembly (GO:0007416)2.87564813
71olfactory bulb development (GO:0021772)2.86021574
72ganglion development (GO:0061548)2.84798015
73camera-type eye morphogenesis (GO:0048593)2.84106694
74neuromuscular process controlling balance (GO:0050885)2.81807474
75positive regulation of membrane potential (GO:0045838)2.80936262
76long-term memory (GO:0007616)2.78642245
77regulation of synaptic plasticity (GO:0048167)2.77556302
78negative regulation of axon guidance (GO:1902668)2.77541248
79cellular potassium ion homeostasis (GO:0030007)2.76743859
80presynaptic membrane organization (GO:0097090)2.76415359
81somite development (GO:0061053)2.76250986
82negative regulation of cytosolic calcium ion concentration (GO:0051481)2.75916328
83calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.75858596
84response to auditory stimulus (GO:0010996)2.75594606
85regulation of axon guidance (GO:1902667)2.74993650
86regulation of synaptic transmission, glutamatergic (GO:0051966)2.74737044
87gamma-aminobutyric acid signaling pathway (GO:0007214)2.74186662
88negative regulation of axon extension involved in axon guidance (GO:0048843)2.72643900
89positive regulation of synapse assembly (GO:0051965)2.72439679
90long-term synaptic potentiation (GO:0060291)2.71734983
91regulation of axon extension involved in axon guidance (GO:0048841)2.71715561
92sympathetic nervous system development (GO:0048485)2.71504938
93nonmotile primary cilium assembly (GO:0035058)2.71099383
94positive regulation of dendritic spine morphogenesis (GO:0061003)2.70315210
95apical protein localization (GO:0045176)2.69265635
96regulation of synapse assembly (GO:0051963)2.68265477
97regulation of synapse maturation (GO:0090128)2.68138451
98synapse organization (GO:0050808)2.67077483
99regulation of vesicle fusion (GO:0031338)2.66787794
100mechanosensory behavior (GO:0007638)2.65741467
101regulation of cAMP-dependent protein kinase activity (GO:2000479)2.65534803
102establishment of mitochondrion localization (GO:0051654)2.65338932
103regulation of respiratory system process (GO:0044065)2.65296464
104appendage development (GO:0048736)2.64961796
105limb development (GO:0060173)2.64961796
106suckling behavior (GO:0001967)2.64544261
107positive regulation of dendritic spine development (GO:0060999)2.64406541
108activation of protein kinase A activity (GO:0034199)2.63665113
109epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.62394446
110regulation of neurotransmitter secretion (GO:0046928)2.60529873
111prepulse inhibition (GO:0060134)2.59845088
112membrane depolarization (GO:0051899)2.59274023
113behavioral defense response (GO:0002209)2.59206808
114behavioral fear response (GO:0001662)2.59206808
115negative regulation of amino acid transport (GO:0051956)2.58831681
116central nervous system myelination (GO:0022010)2.58202787
117axon ensheathment in central nervous system (GO:0032291)2.58202787
118neuron migration (GO:0001764)2.57691195
119regulation of dendritic spine development (GO:0060998)2.57589867
120neurotransmitter transport (GO:0006836)2.57568346
121cell proliferation in forebrain (GO:0021846)2.57419266
122neuron projection extension involved in neuron projection guidance (GO:1902284)2.57058176
123axon extension involved in axon guidance (GO:0048846)2.57058176
124negative regulation of astrocyte differentiation (GO:0048712)2.56050784
125learning (GO:0007612)2.55777508
126axon extension (GO:0048675)2.53392503
127membrane depolarization during action potential (GO:0086010)2.52810704
128negative regulation of axon extension (GO:0030517)2.52321497
129tongue development (GO:0043586)2.52143800
130regulation of synapse organization (GO:0050807)2.51860918
131glycine transport (GO:0015816)2.50966184
132neuron projection extension (GO:1990138)2.49556383
133adult walking behavior (GO:0007628)2.43977983
134axonogenesis (GO:0007409)2.43974120
135gamma-aminobutyric acid transport (GO:0015812)2.43493843
136negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.42893537
137neuromuscular synaptic transmission (GO:0007274)2.42461659
138paraxial mesoderm development (GO:0048339)2.41008078
139behavioral response to ethanol (GO:0048149)2.40488523
140negative regulation of axonogenesis (GO:0050771)2.40388460
141epithelial cilium movement (GO:0003351)2.40375609
142hippocampus development (GO:0021766)2.39787082
143dopaminergic neuron differentiation (GO:0071542)2.39512912
144negative regulation of dendrite development (GO:2000171)2.36839833
145thalamus development (GO:0021794)2.36201084
146substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.35901111
147substrate-independent telencephalic tangential migration (GO:0021826)2.35901111
148forebrain neuron differentiation (GO:0021879)2.34847156
149cerebral cortex cell migration (GO:0021795)2.34107619
150hindbrain development (GO:0030902)2.33303284
151inner ear receptor stereocilium organization (GO:0060122)2.32862160
152homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.32852479

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.19228752
2GBX2_23144817_ChIP-Seq_PC3_Human3.49773292
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.03398434
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.96521797
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.95861482
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.86966699
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.86966699
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.75164951
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.71410441
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.64247843
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59107627
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.57072492
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52311558
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.42448644
15RNF2_27304074_Chip-Seq_ESCs_Mouse2.37048088
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32792234
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.31537649
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21740097
19DROSHA_22980978_ChIP-Seq_HELA_Human2.20564563
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.20511520
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.19069126
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.16684903
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.14416397
24REST_21632747_ChIP-Seq_MESCs_Mouse2.09722473
25RARB_27405468_Chip-Seq_BRAIN_Mouse1.95815393
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85605870
27PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.83077163
28RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.80693297
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75131850
30AR_21572438_ChIP-Seq_LNCaP_Human1.73580601
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.71436579
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69193718
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.65371429
34TAF15_26573619_Chip-Seq_HEK293_Human1.64495318
35CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.64100239
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.62385745
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.61814077
38EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61214005
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.58918534
40IGF1R_20145208_ChIP-Seq_DFB_Human1.58899291
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.55416492
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53045430
43BMI1_23680149_ChIP-Seq_NPCS_Mouse1.52431180
44SMAD4_21799915_ChIP-Seq_A2780_Human1.51081639
45RING1B_27294783_Chip-Seq_ESCs_Mouse1.47504593
46MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45700540
47RING1B_27294783_Chip-Seq_NPCs_Mouse1.45029848
48IKZF1_21737484_ChIP-ChIP_HCT116_Human1.41940050
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.41284511
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.41155570
51AHR_22903824_ChIP-Seq_MCF-7_Human1.38454286
52WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.37861919
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37137982
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.36762773
55* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.36415474
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36398957
57VDR_22108803_ChIP-Seq_LS180_Human1.35881698
58ARNT_22903824_ChIP-Seq_MCF-7_Human1.34537906
59EWS_26573619_Chip-Seq_HEK293_Human1.33199367
60P300_19829295_ChIP-Seq_ESCs_Human1.32996856
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.31381128
62ZNF274_21170338_ChIP-Seq_K562_Hela1.30987143
63OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27770201
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.26678995
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.26229686
66AR_19668381_ChIP-Seq_PC3_Human1.24550739
67SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23947178
68RNF2_27304074_Chip-Seq_NSC_Mouse1.23655774
69LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22763198
70STAT3_23295773_ChIP-Seq_U87_Human1.22538019
71KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.22374359
72MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.22099363
73TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21639355
74TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.18124178
75TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17798926
76YAP1_20516196_ChIP-Seq_MESCs_Mouse1.17695605
77CDX2_19796622_ChIP-Seq_MESCs_Mouse1.16758539
78SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.16382298
79STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16083890
80AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15923619
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15704584
82TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.15200443
83AR_25329375_ChIP-Seq_VCAP_Human1.14574180
84NR3C1_23031785_ChIP-Seq_PC12_Mouse1.14407994
85TP53_20018659_ChIP-ChIP_R1E_Mouse1.13866159
86FUS_26573619_Chip-Seq_HEK293_Human1.13824109
87ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.13809612
88EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12829077
89TP53_16413492_ChIP-PET_HCT116_Human1.11786881
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.10653757
91SOX9_26525672_Chip-Seq_HEART_Mouse1.10519591
92TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09215684
93TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.09125547
94ZFP281_18757296_ChIP-ChIP_E14_Mouse1.09047881
95NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05335745
96POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04835349
97TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04835349
98ISL1_27105846_Chip-Seq_CPCs_Mouse1.04398494
99MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03765072
100TP63_19390658_ChIP-ChIP_HaCaT_Human1.03382869
101KDM2B_26808549_Chip-Seq_K562_Human1.02853195
102TBX3_20139965_ChIP-Seq_MESCs_Mouse1.02515645
103RUNX2_22187159_ChIP-Seq_PCA_Human1.02207079
104TBX3_20139965_ChIP-Seq_ESCs_Mouse1.01824155
105POU3F2_20337985_ChIP-ChIP_501MEL_Human1.01770913
106TCF4_23295773_ChIP-Seq_U87_Human1.01269078
107CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00536811
108TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98906877
109P53_22127205_ChIP-Seq_FIBROBLAST_Human0.98803696
110OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.97357099
111TP53_18474530_ChIP-ChIP_U2OS_Human0.97244373
112TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97044112
113SMAD4_21741376_ChIP-Seq_HESCs_Human0.96417721
114SMAD3_21741376_ChIP-Seq_ESCs_Human0.94860939
115MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94272409
116UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93702714
117TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.93696843
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93067623
119BCAT_22108803_ChIP-Seq_LS180_Human0.92298798
120ZFP281_27345836_Chip-Seq_ESCs_Mouse0.89537768
121STAT6_21828071_ChIP-Seq_BEAS2B_Human0.89460708
122SMAD3_21741376_ChIP-Seq_HESCs_Human0.88777847

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.54038880
2MP0003880_abnormal_central_pattern3.81043161
3MP0003635_abnormal_synaptic_transmissio3.08835914
4MP0004270_analgesia2.85085620
5MP0002063_abnormal_learning/memory/cond2.56953720
6MP0009745_abnormal_behavioral_response2.38292103
7MP0000566_synostosis2.29678702
8MP0000778_abnormal_nervous_system2.22179494
9MP0002064_seizures2.20299295
10MP0001486_abnormal_startle_reflex2.18816418
11MP0005423_abnormal_somatic_nervous2.18255500
12MP0003122_maternal_imprinting2.08207622
13MP0002572_abnormal_emotion/affect_behav2.06011087
14MP0009046_muscle_twitch1.99231676
15MP0002272_abnormal_nervous_system1.98159138
16MP0009780_abnormal_chondrocyte_physiolo1.90852853
17MP0001501_abnormal_sleep_pattern1.89031202
18MP0002734_abnormal_mechanical_nocicepti1.88233985
19MP0001968_abnormal_touch/_nociception1.81770441
20MP0003283_abnormal_digestive_organ1.80004809
21MP0002822_catalepsy1.77252876
22MP0002184_abnormal_innervation1.75955781
23MP0003879_abnormal_hair_cell1.68376395
24MP0004858_abnormal_nervous_system1.65388541
25MP0002751_abnormal_autonomic_nervous1.58816222
26MP0005503_abnormal_tendon_morphology1.57474125
27MP0003787_abnormal_imprinting1.55427302
28MP0005499_abnormal_olfactory_system1.54754949
29MP0005394_taste/olfaction_phenotype1.54754949
30MP0001984_abnormal_olfaction1.51959816
31MP0006276_abnormal_autonomic_nervous1.49639728
32MP0005645_abnormal_hypothalamus_physiol1.49306673
33MP0003937_abnormal_limbs/digits/tail_de1.45390086
34MP0002067_abnormal_sensory_capabilities1.45076586
35MP0002557_abnormal_social/conspecific_i1.44575260
36MP0001529_abnormal_vocalization1.43817433
37MP0002938_white_spotting1.41948816
38MP0000955_abnormal_spinal_cord1.39679074
39MP0002882_abnormal_neuron_morphology1.38757934
40MP0005386_behavior/neurological_phenoty1.35570248
41MP0004924_abnormal_behavior1.35570248
42MP0002909_abnormal_adrenal_gland1.35240219
43MP0001440_abnormal_grooming_behavior1.34739957
44MP0002234_abnormal_pharynx_morphology1.33528829
45MP0004811_abnormal_neuron_physiology1.27851427
46MP0010030_abnormal_orbit_morphology1.27577526
47MP0005248_abnormal_Harderian_gland1.27040079
48MP0004885_abnormal_endolymph1.25138724
49MP0003121_genomic_imprinting1.24448921
50MP0008789_abnormal_olfactory_epithelium1.24216303
51MP0008569_lethality_at_weaning1.24148272
52MP0002733_abnormal_thermal_nociception1.23903505
53MP0005623_abnormal_meninges_morphology1.22899401
54MP0002736_abnormal_nociception_after1.22732902
55MP0002653_abnormal_ependyma_morphology1.21966573
56MP0001293_anophthalmia1.21879348
57MP0000751_myopathy1.21334778
58MP0001970_abnormal_pain_threshold1.20916357
59MP0003136_yellow_coat_color1.20714884
60MP0004233_abnormal_muscle_weight1.19626503
61MP0004145_abnormal_muscle_electrophysio1.18706081
62MP0002152_abnormal_brain_morphology1.17641497
63MP0009053_abnormal_anal_canal1.13103684
64MP0000631_abnormal_neuroendocrine_gland1.12664488
65MP0000013_abnormal_adipose_tissue1.12542411
66MP0001485_abnormal_pinna_reflex1.11628593
67MP0002066_abnormal_motor_capabilities/c1.09521319
68MP0005253_abnormal_eye_physiology1.09332506
69MP0000537_abnormal_urethra_morphology1.08006403
70MP0004742_abnormal_vestibular_system1.06226630
71MP0004142_abnormal_muscle_tone1.05755495
72MP0009250_abnormal_appendicular_skeleto1.04809899
73MP0000569_abnormal_digit_pigmentation1.04671454
74MP0005551_abnormal_eye_electrophysiolog1.04562358
75MP0000579_abnormal_nail_morphology1.04302071
76MP0000026_abnormal_inner_ear1.03214706
77MP0003861_abnormal_nervous_system1.02605885
78MP0002735_abnormal_chemical_nociception1.02508254
79MP0002697_abnormal_eye_size1.02451112
80MP0002752_abnormal_somatic_nervous1.01864554
81MP0005377_hearing/vestibular/ear_phenot1.00733889
82MP0003878_abnormal_ear_physiology1.00733889
83MP0001177_atelectasis1.00731979
84MP0001502_abnormal_circadian_rhythm1.00159928
85MP0001286_abnormal_eye_development0.98757123
86MP0002102_abnormal_ear_morphology0.98731414
87MP0005391_vision/eye_phenotype0.98257934
88MP0000428_abnormal_craniofacial_morphol0.97606345
89MP0001963_abnormal_hearing_physiology0.95941071
90MP0005195_abnormal_posterior_eye0.95462264
91MP0003938_abnormal_ear_development0.95428031
92MP0003385_abnormal_body_wall0.95181452
93MP0005257_abnormal_intraocular_pressure0.93772747
94MP0000049_abnormal_middle_ear0.93603823
95MP0002116_abnormal_craniofacial_bone0.92106584
96MP0005275_abnormal_skin_tensile0.90996193
97MP0001299_abnormal_eye_distance/0.90908158
98MP0003935_abnormal_craniofacial_develop0.90299670
99MP0005646_abnormal_pituitary_gland0.90178462
100MP0005670_abnormal_white_adipose0.89603041
101MP0002249_abnormal_larynx_morphology0.88359330
102MP0004130_abnormal_muscle_cell0.88284600
103MP0000534_abnormal_ureter_morphology0.88225807
104MP0003119_abnormal_digestive_system0.87181064
105MP0010386_abnormal_urinary_bladder0.86711743
106MP0008961_abnormal_basal_metabolism0.86661237
107MP0006292_abnormal_olfactory_placode0.86412210
108MP0002837_dystrophic_cardiac_calcinosis0.86341786
109MP0002876_abnormal_thyroid_physiology0.85457238
110MP0003942_abnormal_urinary_system0.85452053
111MP0006072_abnormal_retinal_apoptosis0.85155709
112MP0003329_amyloid_beta_deposits0.84683692
113MP0001346_abnormal_lacrimal_gland0.83653459
114MP0002069_abnormal_eating/drinking_beha0.83000676
115MP0003123_paternal_imprinting0.82893081
116MP0000003_abnormal_adipose_tissue0.82653283
117MP0005187_abnormal_penis_morphology0.82319956
118MP0001188_hyperpigmentation0.81833350
119MP0002233_abnormal_nose_morphology0.81472102
120MP0003755_abnormal_palate_morphology0.81128118
121MP0002638_abnormal_pupillary_reflex0.80923106
122MP0003633_abnormal_nervous_system0.78683695
123MP0003634_abnormal_glial_cell0.76555389
124MP0003890_abnormal_embryonic-extraembry0.75526503
125MP0004133_heterotaxia0.75497235

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.88853709
2Myokymia (HP:0002411)4.42515321
3Focal seizures (HP:0007359)4.08986382
4Epileptic encephalopathy (HP:0200134)3.46342733
5Febrile seizures (HP:0002373)3.35663136
6Atonic seizures (HP:0010819)3.30209187
7Progressive cerebellar ataxia (HP:0002073)3.10447816
8Absence seizures (HP:0002121)2.99762732
9Action tremor (HP:0002345)2.98247627
10Visual hallucinations (HP:0002367)2.77221821
11Broad-based gait (HP:0002136)2.73490460
12Ankle clonus (HP:0011448)2.71929595
13Dialeptic seizures (HP:0011146)2.64139681
14Vitreoretinal degeneration (HP:0000655)2.57398138
15Generalized tonic-clonic seizures (HP:0002069)2.56045084
16Genital tract atresia (HP:0001827)2.51552172
17Vaginal atresia (HP:0000148)2.51513494
18Excessive salivation (HP:0003781)2.50493804
19Drooling (HP:0002307)2.50493804
20Abnormality of the 4th metacarpal (HP:0010012)2.50137454
21Midline defect of the nose (HP:0004122)2.48960486
22Amblyopia (HP:0000646)2.43710504
23Renal hypoplasia (HP:0000089)2.43370726
24Hyperthyroidism (HP:0000836)2.42346225
25Supranuclear gaze palsy (HP:0000605)2.42305555
26Intestinal atresia (HP:0011100)2.38135574
27Oligodactyly (hands) (HP:0001180)2.37254441
28Gait imbalance (HP:0002141)2.37188456
29Hyperventilation (HP:0002883)2.37066078
30Nephronophthisis (HP:0000090)2.36497779
31Shawl scrotum (HP:0000049)2.34353321
32Aplasia involving bones of the extremities (HP:0009825)2.32710166
33Aplasia involving bones of the upper limbs (HP:0009823)2.32710166
34Aplasia of the phalanges of the hand (HP:0009802)2.32710166
35Abnormality of midbrain morphology (HP:0002418)2.31977575
36Molar tooth sign on MRI (HP:0002419)2.31977575
37Genetic anticipation (HP:0003743)2.31808328
38Dysdiadochokinesis (HP:0002075)2.30752645
39Poor eye contact (HP:0000817)2.30643873
40Urinary bladder sphincter dysfunction (HP:0002839)2.29842222
41Oligodactyly (HP:0012165)2.28536387
42Medial flaring of the eyebrow (HP:0010747)2.25425975
43Impaired vibration sensation in the lower limbs (HP:0002166)2.23174554
44Limb dystonia (HP:0002451)2.20513056
45True hermaphroditism (HP:0010459)2.19555356
46Abnormal eating behavior (HP:0100738)2.18295240
47Insidious onset (HP:0003587)2.14214102
48Termporal pattern (HP:0011008)2.14214102
49Hepatoblastoma (HP:0002884)2.13291755
50Truncal ataxia (HP:0002078)2.13062016
51Preaxial foot polydactyly (HP:0001841)2.11822593
52Gaze-evoked nystagmus (HP:0000640)2.11476500
53Abnormal social behavior (HP:0012433)2.07511105
54Impaired social interactions (HP:0000735)2.07511105
55Pancreatic fibrosis (HP:0100732)2.06983464
56Cerebral inclusion bodies (HP:0100314)2.04969705
57Congenital primary aphakia (HP:0007707)2.03243081
58Dysmetria (HP:0001310)2.02470061
59Abnormality of the aortic arch (HP:0012303)2.02221846
60Abnormality of the renal medulla (HP:0100957)2.01694428
61Ankyloglossia (HP:0010296)2.00246082
62Lower limb muscle weakness (HP:0007340)1.99463076
63Abnormality of the corticospinal tract (HP:0002492)1.99152215
64Renal duplication (HP:0000075)1.99133495
65Abnormality of the ischium (HP:0003174)1.98504759
66Abnormality of the phalanges of the 2nd finger (HP:0009541)1.98114159
67High anterior hairline (HP:0009890)1.97946052
68Exotropia (HP:0000577)1.97201443
69Cutaneous finger syndactyly (HP:0010554)1.97154220
70Aqueductal stenosis (HP:0002410)1.96416714
71Depression (HP:0000716)1.93251661
72Optic nerve hypoplasia (HP:0000609)1.93136993
73Chronic hepatic failure (HP:0100626)1.91915774
74Pancreatic cysts (HP:0001737)1.91026270
75Macroorchidism (HP:0000053)1.90994693
76Hemiparesis (HP:0001269)1.90797872
77Hypoventilation (HP:0002791)1.89009426
78Rib fusion (HP:0000902)1.88417251
79Partial duplication of the phalanx of hand (HP:0009999)1.88264322
80Anophthalmia (HP:0000528)1.87796546
81Hypoplastic ischia (HP:0003175)1.87544466
82Septo-optic dysplasia (HP:0100842)1.87191367
83Neurofibrillary tangles (HP:0002185)1.85908405
84Narrow nasal bridge (HP:0000446)1.85638761
85Postaxial hand polydactyly (HP:0001162)1.85332027
86Pachygyria (HP:0001302)1.84937644
87Insomnia (HP:0100785)1.84872966
88Lissencephaly (HP:0001339)1.84631175
89Spastic gait (HP:0002064)1.84352029
90Degeneration of the lateral corticospinal tracts (HP:0002314)1.83174020
91Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.83174020
92Nephrogenic diabetes insipidus (HP:0009806)1.82154015
93Absent speech (HP:0001344)1.81421964
94Alacrima (HP:0000522)1.80935084
95Abnormality of salivation (HP:0100755)1.80717191
96Urinary urgency (HP:0000012)1.80513945
97Bicornuate uterus (HP:0000813)1.79913656
98Buphthalmos (HP:0000557)1.79684165
99Occipital encephalocele (HP:0002085)1.79461154
100Turricephaly (HP:0000262)1.79100619
101Volvulus (HP:0002580)1.78956683
102Gastrointestinal atresia (HP:0002589)1.77426267
103Epileptiform EEG discharges (HP:0011182)1.74252459
104Pheochromocytoma (HP:0002666)1.74178082
105Torticollis (HP:0000473)1.73812599
106Megalencephaly (HP:0001355)1.73320223
107Aplasia/Hypoplasia of the sternum (HP:0006714)1.72896940
108Synostosis involving the elbow (HP:0003938)1.72657203
109Humeroradial synostosis (HP:0003041)1.72657203
110Narrow forehead (HP:0000341)1.72559265
111Renal dysplasia (HP:0000110)1.71197071
112Labial hypoplasia (HP:0000066)1.71047366
113Pointed chin (HP:0000307)1.70918871
114Esophageal atresia (HP:0002032)1.70453315
115Abnormality of the pubic bones (HP:0003172)1.70334215
116Cutaneous syndactyly (HP:0012725)1.70060247
117Bifid tongue (HP:0010297)1.69493175
118Abnormality of the diencephalon (HP:0010662)1.68217600
119Anxiety (HP:0000739)1.67547856
120Polyphagia (HP:0002591)1.67431534
121EEG with generalized epileptiform discharges (HP:0011198)1.66639557
122Scanning speech (HP:0002168)1.66555849
123Bilateral microphthalmos (HP:0007633)1.65790813
124Abnormality of the antihelix (HP:0009738)1.64891486
125Wide anterior fontanel (HP:0000260)1.64527667
126Micropenis (HP:0000054)1.64376716
127Morphological abnormality of the middle ear (HP:0008609)1.63114254
128Specific learning disability (HP:0001328)1.63087229
129Bowel incontinence (HP:0002607)1.62877580
130Shallow orbits (HP:0000586)1.61479736
131Aplasia/Hypoplasia of the lens (HP:0008063)1.61348448
132Abnormality of the labia minora (HP:0012880)1.61323099
133Abnormal respiratory epithelium morphology (HP:0012253)1.61291372
134Abnormal respiratory motile cilium morphology (HP:0005938)1.61291372
135Intellectual disability, moderate (HP:0002342)1.61204508
136Mutism (HP:0002300)1.61003459
137Intention tremor (HP:0002080)1.60884025
138Hypoplastic labia majora (HP:0000059)1.60058976
139Stereotypic behavior (HP:0000733)1.59348959
140Poor coordination (HP:0002370)1.58632437
141Broad metatarsal (HP:0001783)1.58441333
142Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.58373715
143Neoplasm of the heart (HP:0100544)1.56960166
144Protruding tongue (HP:0010808)1.56858387
145Bronchomalacia (HP:0002780)1.56851788
146Impaired smooth pursuit (HP:0007772)1.55810336
147Mixed hearing impairment (HP:0000410)1.54787317
148Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.53497066
149Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.52612898
150Short 4th metacarpal (HP:0010044)1.52612898
151Abnormality of the lower motor neuron (HP:0002366)1.52132761
152Autism (HP:0000717)1.51773029
153Postural instability (HP:0002172)1.51186793
154Hypoplastic female external genitalia (HP:0012815)1.48672473
155Hypsarrhythmia (HP:0002521)1.47998762
156Decreased lacrimation (HP:0000633)1.46819386
157Aplasia/Hypoplasia of the brainstem (HP:0007362)1.46628443
158Hypoplasia of the brainstem (HP:0002365)1.46628443
159Focal dystonia (HP:0004373)1.46084726
160Coronal craniosynostosis (HP:0004440)1.45990220

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.01444819
2NTRK33.58785840
3MAP3K92.98704366
4MARK12.91639765
5MAP3K42.76701327
6NTRK22.46682665
7FRK2.38575882
8MINK12.29747542
9KSR12.23120551
10DAPK22.19700261
11PAK62.09494662
12CAMK1G2.06554440
13NTRK12.03760865
14DYRK21.98992724
15CASK1.87985524
16ICK1.83620348
17MAP2K71.78137444
18PRKD31.70506144
19CAMK1D1.68023074
20PNCK1.65870422
21DDR21.65057591
22EPHB21.61705516
23MAPK131.52553594
24BCR1.52095860
25UHMK11.50399754
26MAP2K41.48943092
27FGFR21.46758021
28PLK21.42787784
29MKNK21.41633255
30TYRO31.38495823
31PRPF4B1.32546014
32CDK51.31768757
33KSR21.28942094
34LATS21.27258162
35BMPR1B1.20933983
36INSRR1.19681902
37EPHA31.18920380
38MAPK151.18473531
39PINK11.12012944
40DAPK11.10985922
41STK38L1.10551191
42PLK41.09761720
43FER1.07551024
44SIK21.07278213
45ERBB31.03266135
46SGK2231.01132723
47SGK4941.01132723
48TNIK0.98312247
49WNK40.98073091
50SIK30.96942443
51PHKG20.95343702
52PHKG10.95343702
53CDK190.95284743
54ADRBK20.93525637
55MKNK10.92464872
56DYRK30.92438366
57MARK20.90356305
58CSNK1G10.89542537
59PRKCG0.89025484
60GRK50.88011194
61CAMKK10.86760994
62CDK180.86363875
63PAK30.84374385
64MAP3K120.82437165
65MAP4K20.82371501
66CDK140.82336546
67RIPK10.81918028
68CDK150.79405258
69STK380.76971289
70DYRK1A0.75502093
71CAMK2A0.75211064
72PDGFRA0.73351847
73ARAF0.72031005
74OXSR10.71775233
75CSNK1G30.71761466
76WNK30.71430630
77WEE10.70606055
78CAMK10.68375350
79SGK10.67198494
80STK110.66891590
81MAP3K20.66305642
82CDK11A0.66303218
83GRK10.65922513
84TRIM280.65170625
85CSNK1G20.65018207
86RET0.64380103
87CAMK2B0.64256798
88SGK20.63444498
89LMTK20.63142815
90PRKCH0.62264400
91WNK10.62147324
92SIK10.61999762
93PTK2B0.61078447
94PRKCE0.60176230
95FGFR10.59686842
96MAP3K100.57911965
97ERBB20.57307746
98ROCK20.56789721
99STK390.55132669
100MAPK100.54774550
101NUAK10.54585956
102RIPK40.54564580
103CSNK1A1L0.53135960
104TAOK10.53124293
105ADRBK10.52770291
106CDC42BPA0.52385904
107FGR0.52017671
108DYRK1B0.51675888
109PRKCZ0.50880597
110RPS6KA30.50282252
111TNK20.49915883
112LATS10.49209657
113NEK20.48000525
114MAP2K10.46194703
115CAMK40.45991978
116TGFBR10.45820844
117CSNK1D0.45719708
118AKT30.45631154
119CDK30.45553711
120PDGFRB0.44746721
121RPS6KA20.44727934
122NEK60.44667220
123TRIB30.44595284
124PRKG10.43915852
125CCNB10.43673456
126CSNK1E0.43529278
127DMPK0.43141612
128PKN10.43033742
129ROCK10.41782232
130SGK30.41483244
131FYN0.41248084
132PRKACA0.38613503

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.34222586
2Synaptic vesicle cycle_Homo sapiens_hsa047212.47112086
3GABAergic synapse_Homo sapiens_hsa047272.42902483
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.41603811
5Circadian entrainment_Homo sapiens_hsa047132.41317518
6Olfactory transduction_Homo sapiens_hsa047402.31045721
7Morphine addiction_Homo sapiens_hsa050322.28182672
8Glutamatergic synapse_Homo sapiens_hsa047242.25559730
9Long-term potentiation_Homo sapiens_hsa047202.13302682
10Dopaminergic synapse_Homo sapiens_hsa047282.03890226
11Amphetamine addiction_Homo sapiens_hsa050312.01499703
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.01244086
13Salivary secretion_Homo sapiens_hsa049701.94927512
14Renin secretion_Homo sapiens_hsa049241.85899905
15Axon guidance_Homo sapiens_hsa043601.84595043
16Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.78142418
17Cholinergic synapse_Homo sapiens_hsa047251.72818587
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.67753506
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.67660763
20Insulin secretion_Homo sapiens_hsa049111.65420311
21Taste transduction_Homo sapiens_hsa047421.58540162
22Long-term depression_Homo sapiens_hsa047301.57859905
23Serotonergic synapse_Homo sapiens_hsa047261.56059941
24Gastric acid secretion_Homo sapiens_hsa049711.54921505
25Cocaine addiction_Homo sapiens_hsa050301.54701618
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.53184290
27Oxytocin signaling pathway_Homo sapiens_hsa049211.48159095
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.44543517
29Calcium signaling pathway_Homo sapiens_hsa040201.44349888
30Melanogenesis_Homo sapiens_hsa049161.43790171
31Fatty acid biosynthesis_Homo sapiens_hsa000611.40211142
32Gap junction_Homo sapiens_hsa045401.38611759
33Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.37404822
34Basal cell carcinoma_Homo sapiens_hsa052171.31389402
35cAMP signaling pathway_Homo sapiens_hsa040241.28916089
36GnRH signaling pathway_Homo sapiens_hsa049121.28040885
37Type II diabetes mellitus_Homo sapiens_hsa049301.23471459
38Hedgehog signaling pathway_Homo sapiens_hsa043401.21972808
39ErbB signaling pathway_Homo sapiens_hsa040121.18338749
40Phototransduction_Homo sapiens_hsa047441.17489690
41Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.14638926
42Estrogen signaling pathway_Homo sapiens_hsa049151.14207604
43Glioma_Homo sapiens_hsa052141.10499056
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10368872
45Wnt signaling pathway_Homo sapiens_hsa043101.09293531
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.08454317
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.07558859
48Steroid biosynthesis_Homo sapiens_hsa001001.05632021
49Butanoate metabolism_Homo sapiens_hsa006501.03311634
50Hippo signaling pathway_Homo sapiens_hsa043900.98599514
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.97917817
52Dorso-ventral axis formation_Homo sapiens_hsa043200.97225349
53Oocyte meiosis_Homo sapiens_hsa041140.93230481
54Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.90946162
55Protein digestion and absorption_Homo sapiens_hsa049740.90736969
56Collecting duct acid secretion_Homo sapiens_hsa049660.89696977
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88600461
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.88358607
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86662774
60Dilated cardiomyopathy_Homo sapiens_hsa054140.83991186
61Ovarian steroidogenesis_Homo sapiens_hsa049130.83452179
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.82677697
63Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81213112
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80506452
65Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.79820639
66alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.79234210
67Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75887251
68Thyroid hormone synthesis_Homo sapiens_hsa049180.73433882
69Endometrial cancer_Homo sapiens_hsa052130.73132732
70MAPK signaling pathway_Homo sapiens_hsa040100.72946880
71Choline metabolism in cancer_Homo sapiens_hsa052310.72897637
72Propanoate metabolism_Homo sapiens_hsa006400.72247170
73Maturity onset diabetes of the young_Homo sapiens_hsa049500.71793394
74mTOR signaling pathway_Homo sapiens_hsa041500.71467228
75Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.71446159
76Ras signaling pathway_Homo sapiens_hsa040140.70994917
77Lysine degradation_Homo sapiens_hsa003100.70477910
78Ether lipid metabolism_Homo sapiens_hsa005650.70336287
79Glucagon signaling pathway_Homo sapiens_hsa049220.69982080
80AMPK signaling pathway_Homo sapiens_hsa041520.68411789
81Rap1 signaling pathway_Homo sapiens_hsa040150.67940125
82Cardiac muscle contraction_Homo sapiens_hsa042600.67742093
83Alcoholism_Homo sapiens_hsa050340.67573552
84Renal cell carcinoma_Homo sapiens_hsa052110.66551704
85Pancreatic secretion_Homo sapiens_hsa049720.66501889
86Insulin signaling pathway_Homo sapiens_hsa049100.65694793
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65177201
88Tight junction_Homo sapiens_hsa045300.65090666
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64885042
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64511075
91Vibrio cholerae infection_Homo sapiens_hsa051100.63922822
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63666935
93Linoleic acid metabolism_Homo sapiens_hsa005910.63122373
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.62479416
95Colorectal cancer_Homo sapiens_hsa052100.62109512
96Protein export_Homo sapiens_hsa030600.60465020
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60361800
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58361500
99Nitrogen metabolism_Homo sapiens_hsa009100.58332122
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.57995871
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.56706978
102Pathways in cancer_Homo sapiens_hsa052000.55944852
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54319965
104VEGF signaling pathway_Homo sapiens_hsa043700.52974659
105Circadian rhythm_Homo sapiens_hsa047100.51823974
106Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.47173619
107Basal transcription factors_Homo sapiens_hsa030220.47092971
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46886513
109Proteoglycans in cancer_Homo sapiens_hsa052050.46084777
110Huntingtons disease_Homo sapiens_hsa050160.44665504
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44593251
112Notch signaling pathway_Homo sapiens_hsa043300.44413980
113Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44360126
114TGF-beta signaling pathway_Homo sapiens_hsa043500.44237713
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.44148654
116ECM-receptor interaction_Homo sapiens_hsa045120.43888140
117Non-small cell lung cancer_Homo sapiens_hsa052230.43451457
118beta-Alanine metabolism_Homo sapiens_hsa004100.43236793
119Glycerolipid metabolism_Homo sapiens_hsa005610.41878133
120Inositol phosphate metabolism_Homo sapiens_hsa005620.41726684
121Focal adhesion_Homo sapiens_hsa045100.41312227
122Melanoma_Homo sapiens_hsa052180.40613644
123Adherens junction_Homo sapiens_hsa045200.39552155
124Endocytosis_Homo sapiens_hsa041440.38830905

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