

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.57340911 |
| 2 | DNA double-strand break processing (GO:0000729) | 5.32770214 |
| 3 | protein neddylation (GO:0045116) | 5.15396781 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 5.10033970 |
| 5 | DNA strand renaturation (GO:0000733) | 4.81708773 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.65977787 |
| 7 | ATP synthesis coupled proton transport (GO:0015986) | 4.64427271 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.64427271 |
| 9 | chromatin remodeling at centromere (GO:0031055) | 4.58258342 |
| 10 | DNA replication checkpoint (GO:0000076) | 4.32994014 |
| 11 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 4.29742099 |
| 12 | respiratory electron transport chain (GO:0022904) | 4.29443684 |
| 13 | electron transport chain (GO:0022900) | 4.16985081 |
| 14 | signal peptide processing (GO:0006465) | 4.12235331 |
| 15 | DNA deamination (GO:0045006) | 4.11279215 |
| 16 | pseudouridine synthesis (GO:0001522) | 4.11153746 |
| 17 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.02324319 |
| 18 | CENP-A containing nucleosome assembly (GO:0034080) | 3.94764867 |
| 19 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.92956519 |
| 20 | cullin deneddylation (GO:0010388) | 3.92571991 |
| 21 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.86789908 |
| 22 | histone mRNA metabolic process (GO:0008334) | 3.85718754 |
| 23 | respiratory chain complex IV assembly (GO:0008535) | 3.85613754 |
| 24 | fatty acid elongation (GO:0030497) | 3.83974428 |
| 25 | proteasome assembly (GO:0043248) | 3.83657883 |
| 26 | protein complex biogenesis (GO:0070271) | 3.78459046 |
| 27 | termination of RNA polymerase III transcription (GO:0006386) | 3.75671619 |
| 28 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.75671619 |
| 29 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.72666940 |
| 30 | cytochrome complex assembly (GO:0017004) | 3.63655678 |
| 31 | DNA damage response, detection of DNA damage (GO:0042769) | 3.63000361 |
| 32 | mismatch repair (GO:0006298) | 3.62439649 |
| 33 | meiotic chromosome segregation (GO:0045132) | 3.52305242 |
| 34 | rRNA modification (GO:0000154) | 3.51022785 |
| 35 | histone exchange (GO:0043486) | 3.50537454 |
| 36 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.49798079 |
| 37 | transcription from mitochondrial promoter (GO:0006390) | 3.47738364 |
| 38 | protein deneddylation (GO:0000338) | 3.45725162 |
| 39 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.41713559 |
| 40 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.41713559 |
| 41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.39179826 |
| 42 | NADH dehydrogenase complex assembly (GO:0010257) | 3.39179826 |
| 43 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.39179826 |
| 44 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.38390080 |
| 45 | regulation of mitochondrial translation (GO:0070129) | 3.33731603 |
| 46 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.29991498 |
| 47 | nucleobase biosynthetic process (GO:0046112) | 3.26941531 |
| 48 | purine nucleobase biosynthetic process (GO:0009113) | 3.25935582 |
| 49 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.25413238 |
| 50 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.25413238 |
| 51 | replication fork processing (GO:0031297) | 3.24033682 |
| 52 | mitochondrial RNA metabolic process (GO:0000959) | 3.18841504 |
| 53 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.15646891 |
| 54 | negative regulation of ligase activity (GO:0051352) | 3.15646891 |
| 55 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.15587512 |
| 56 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.14918405 |
| 57 | cytidine deamination (GO:0009972) | 3.13983595 |
| 58 | cytidine metabolic process (GO:0046087) | 3.13983595 |
| 59 | cytidine catabolic process (GO:0006216) | 3.13983595 |
| 60 | spliceosomal snRNP assembly (GO:0000387) | 3.02880518 |
| 61 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.99837672 |
| 62 | double-strand break repair via homologous recombination (GO:0000724) | 2.97892778 |
| 63 | positive regulation of mRNA processing (GO:0050685) | 2.96039358 |
| 64 | recombinational repair (GO:0000725) | 2.95919046 |
| 65 | ubiquinone biosynthetic process (GO:0006744) | 2.95253439 |
| 66 | histone H2A acetylation (GO:0043968) | 2.89515757 |
| 67 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.89056134 |
| 68 | regulation of translational termination (GO:0006449) | 2.86542954 |
| 69 | protein K6-linked ubiquitination (GO:0085020) | 2.84899987 |
| 70 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.83361274 |
| 71 | behavioral response to nicotine (GO:0035095) | 2.82557462 |
| 72 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.81972646 |
| 73 | hydrogen ion transmembrane transport (GO:1902600) | 2.81678156 |
| 74 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.80250930 |
| 75 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.79279954 |
| 76 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.79279954 |
| 77 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.78162712 |
| 78 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.78162712 |
| 79 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.78162712 |
| 80 | adenosine metabolic process (GO:0046085) | 2.76491015 |
| 81 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.74874470 |
| 82 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.74874470 |
| 83 | rRNA processing (GO:0006364) | 2.74165784 |
| 84 | ubiquinone metabolic process (GO:0006743) | 2.72211820 |
| 85 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.71204163 |
| 86 | rRNA methylation (GO:0031167) | 2.70453032 |
| 87 | platelet dense granule organization (GO:0060155) | 2.69472069 |
| 88 | DNA-templated transcription, termination (GO:0006353) | 2.69453046 |
| 89 | termination of RNA polymerase II transcription (GO:0006369) | 2.67453501 |
| 90 | IMP biosynthetic process (GO:0006188) | 2.67249102 |
| 91 | 7-methylguanosine mRNA capping (GO:0006370) | 2.67095818 |
| 92 | pre-miRNA processing (GO:0031054) | 2.66059423 |
| 93 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.65767725 |
| 94 | DNA replication-independent nucleosome organization (GO:0034724) | 2.65767725 |
| 95 | regulation of helicase activity (GO:0051095) | 2.65168015 |
| 96 | tricarboxylic acid cycle (GO:0006099) | 2.65105577 |
| 97 | ribosome assembly (GO:0042255) | 2.64159316 |
| 98 | rRNA metabolic process (GO:0016072) | 2.64138027 |
| 99 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.63823758 |
| 100 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.63219221 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.41492531 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.61887210 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.05324965 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.93646642 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.86767592 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.34152225 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.20777335 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.89181298 |
| 9 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.86279259 |
| 10 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.84539638 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.76224964 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.72100174 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.69220900 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.56551081 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.55700616 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.36404796 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.21822917 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.21045436 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.99572775 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.98441468 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.95322308 |
| 22 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.95171245 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.89385092 |
| 24 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.78904951 |
| 25 | FUS_26573619_Chip-Seq_HEK293_Human | 1.78730510 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.78545104 |
| 27 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.72285214 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.71481305 |
| 29 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.63049123 |
| 30 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.61686297 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.58961425 |
| 32 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.57989603 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.57107075 |
| 34 | VDR_22108803_ChIP-Seq_LS180_Human | 1.55273998 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.49036524 |
| 36 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.47597248 |
| 37 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.40443140 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.37679725 |
| 39 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.37560568 |
| 40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.35664435 |
| 41 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35352031 |
| 42 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.33782916 |
| 43 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.33477733 |
| 44 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.30893384 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.30082170 |
| 46 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.28089548 |
| 47 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.27820936 |
| 48 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.27644247 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.25854636 |
| 50 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.25707186 |
| 51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21558320 |
| 52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21558320 |
| 53 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.19172970 |
| 54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.19100183 |
| 55 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.18962984 |
| 56 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.16810064 |
| 57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.16434783 |
| 58 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.14323450 |
| 59 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13307855 |
| 60 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.12710164 |
| 61 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10143921 |
| 62 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.09558659 |
| 63 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.08890536 |
| 64 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.08767189 |
| 65 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08613443 |
| 66 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.08042157 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.07616105 |
| 68 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.06975812 |
| 69 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.06770741 |
| 70 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.06576153 |
| 71 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.06526588 |
| 72 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.05432684 |
| 73 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.04525312 |
| 74 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.04460602 |
| 75 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.02544325 |
| 76 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02111902 |
| 77 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.00532008 |
| 78 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.99837196 |
| 79 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99317971 |
| 80 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99317971 |
| 81 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98821940 |
| 82 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.98801814 |
| 83 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.97619293 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.96094305 |
| 85 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95862564 |
| 86 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95583937 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95583937 |
| 88 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.94502854 |
| 89 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.93340506 |
| 90 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.93166757 |
| 91 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.93025170 |
| 92 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.92934376 |
| 93 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.91844826 |
| 94 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91292283 |
| 95 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.91192570 |
| 96 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90345849 |
| 97 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.87226907 |
| 98 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.84735596 |
| 99 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.84205301 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.81880493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003941_abnormal_skin_development | 4.18063086 |
| 2 | MP0001188_hyperpigmentation | 4.02716197 |
| 3 | MP0003693_abnormal_embryo_hatching | 3.81302893 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 3.01675738 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.93000724 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.75051251 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.74022580 |
| 8 | MP0009697_abnormal_copulation | 2.64070506 |
| 9 | MP0005423_abnormal_somatic_nervous | 2.56861152 |
| 10 | MP0000579_abnormal_nail_morphology | 2.56566511 |
| 11 | MP0003880_abnormal_central_pattern | 2.54598865 |
| 12 | MP0003123_paternal_imprinting | 2.33109970 |
| 13 | MP0003111_abnormal_nucleus_morphology | 2.23242463 |
| 14 | MP0004043_abnormal_pH_regulation | 2.18561665 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 2.13628565 |
| 16 | MP0008007_abnormal_cellular_replicative | 2.05930089 |
| 17 | MP0003786_premature_aging | 2.05064955 |
| 18 | MP0008932_abnormal_embryonic_tissue | 1.96652138 |
| 19 | MP0008058_abnormal_DNA_repair | 1.95161813 |
| 20 | MP0003195_calcinosis | 1.91792598 |
| 21 | MP0002090_abnormal_vision | 1.91316130 |
| 22 | MP0005253_abnormal_eye_physiology | 1.87934695 |
| 23 | MP0003787_abnormal_imprinting | 1.81763342 |
| 24 | MP0003121_genomic_imprinting | 1.81622972 |
| 25 | MP0001984_abnormal_olfaction | 1.77538369 |
| 26 | MP0006035_abnormal_mitochondrial_morpho | 1.77445203 |
| 27 | MP0010094_abnormal_chromosome_stability | 1.73598490 |
| 28 | MP0003136_yellow_coat_color | 1.70753846 |
| 29 | MP0002736_abnormal_nociception_after | 1.70750549 |
| 30 | MP0002254_reproductive_system_inflammat | 1.70271931 |
| 31 | MP0004133_heterotaxia | 1.68671309 |
| 32 | MP0001661_extended_life_span | 1.64361225 |
| 33 | MP0000647_abnormal_sebaceous_gland | 1.62093702 |
| 34 | MP0001968_abnormal_touch/_nociception | 1.52113910 |
| 35 | MP0003718_maternal_effect | 1.49382572 |
| 36 | MP0008057_abnormal_DNA_replication | 1.46609873 |
| 37 | MP0003806_abnormal_nucleotide_metabolis | 1.40811681 |
| 38 | MP0008872_abnormal_physiological_respon | 1.38429775 |
| 39 | MP0002734_abnormal_mechanical_nocicepti | 1.37416821 |
| 40 | MP0001529_abnormal_vocalization | 1.30919422 |
| 41 | MP0002102_abnormal_ear_morphology | 1.29230304 |
| 42 | MP0006036_abnormal_mitochondrial_physio | 1.25954396 |
| 43 | MP0005332_abnormal_amino_acid | 1.21568603 |
| 44 | MP0001485_abnormal_pinna_reflex | 1.21101034 |
| 45 | MP0002837_dystrophic_cardiac_calcinosis | 1.19404268 |
| 46 | MP0003646_muscle_fatigue | 1.19401844 |
| 47 | MP0001177_atelectasis | 1.19264233 |
| 48 | MP0003077_abnormal_cell_cycle | 1.12174913 |
| 49 | MP0009745_abnormal_behavioral_response | 1.09646860 |
| 50 | MP0001293_anophthalmia | 1.08817101 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.08802978 |
| 52 | MP0003011_delayed_dark_adaptation | 1.07957867 |
| 53 | MP0004215_abnormal_myocardial_fiber | 1.01578689 |
| 54 | MP0001764_abnormal_homeostasis | 1.01266810 |
| 55 | MP0002735_abnormal_chemical_nociception | 1.00954846 |
| 56 | MP0000631_abnormal_neuroendocrine_gland | 1.00903564 |
| 57 | MP0003950_abnormal_plasma_membrane | 0.94565996 |
| 58 | MP0005410_abnormal_fertilization | 0.92773230 |
| 59 | MP0003119_abnormal_digestive_system | 0.90323681 |
| 60 | MP0001986_abnormal_taste_sensitivity | 0.89905396 |
| 61 | MP0002751_abnormal_autonomic_nervous | 0.89835032 |
| 62 | MP0003122_maternal_imprinting | 0.89365533 |
| 63 | MP0009379_abnormal_foot_pigmentation | 0.88181541 |
| 64 | MP0008789_abnormal_olfactory_epithelium | 0.87945341 |
| 65 | MP0003283_abnormal_digestive_organ | 0.83166896 |
| 66 | MP0009672_abnormal_birth_weight | 0.83087021 |
| 67 | MP0003186_abnormal_redox_activity | 0.81591879 |
| 68 | MP0001970_abnormal_pain_threshold | 0.80209698 |
| 69 | MP0002160_abnormal_reproductive_system | 0.78936551 |
| 70 | MP0002638_abnormal_pupillary_reflex | 0.78695608 |
| 71 | MP0002938_white_spotting | 0.78466025 |
| 72 | MP0005389_reproductive_system_phenotype | 0.77773683 |
| 73 | MP0005084_abnormal_gallbladder_morpholo | 0.77754025 |
| 74 | MP0001905_abnormal_dopamine_level | 0.77658523 |
| 75 | MP0004142_abnormal_muscle_tone | 0.76998217 |
| 76 | MP0005391_vision/eye_phenotype | 0.74603893 |
| 77 | MP0005671_abnormal_response_to | 0.74075929 |
| 78 | MP0002272_abnormal_nervous_system | 0.73064202 |
| 79 | MP0009785_altered_susceptibility_to | 0.71411810 |
| 80 | MP0002693_abnormal_pancreas_physiology | 0.69639276 |
| 81 | MP0005367_renal/urinary_system_phenotyp | 0.69109666 |
| 82 | MP0000516_abnormal_urinary_system | 0.69109666 |
| 83 | MP0002752_abnormal_somatic_nervous | 0.69031410 |
| 84 | MP0000383_abnormal_hair_follicle | 0.67882698 |
| 85 | MP0000467_abnormal_esophagus_morphology | 0.67669053 |
| 86 | MP0002229_neurodegeneration | 0.67570860 |
| 87 | MP0001486_abnormal_startle_reflex | 0.66101480 |
| 88 | MP0001929_abnormal_gametogenesis | 0.63038543 |
| 89 | MP0005195_abnormal_posterior_eye | 0.62843576 |
| 90 | MP0005395_other_phenotype | 0.61423994 |
| 91 | MP0005636_abnormal_mineral_homeostasis | 0.60398192 |
| 92 | MP0008875_abnormal_xenobiotic_pharmacok | 0.60179283 |
| 93 | MP0001853_heart_inflammation | 0.59641562 |
| 94 | MP0000538_abnormal_urinary_bladder | 0.59168867 |
| 95 | MP0009764_decreased_sensitivity_to | 0.58830824 |
| 96 | MP0004019_abnormal_vitamin_homeostasis | 0.58226153 |
| 97 | MP0001919_abnormal_reproductive_system | 0.57992450 |
| 98 | MP0003448_altered_tumor_morphology | 0.57967016 |
| 99 | MP0000427_abnormal_hair_cycle | 0.57914119 |
| 100 | MP0003137_abnormal_impulse_conducting | 0.57297827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.56833543 |
| 2 | Hepatocellular necrosis (HP:0001404) | 4.43278524 |
| 3 | Congenital, generalized hypertrichosis (HP:0004540) | 4.36056292 |
| 4 | Acute encephalopathy (HP:0006846) | 4.33420757 |
| 5 | Mitochondrial inheritance (HP:0001427) | 4.27679647 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.14225465 |
| 7 | Hepatic necrosis (HP:0002605) | 3.93369149 |
| 8 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.80642498 |
| 9 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.80642498 |
| 10 | Increased CSF lactate (HP:0002490) | 3.80045138 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.78698143 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.74237159 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.60740927 |
| 14 | Cerebral edema (HP:0002181) | 3.39287473 |
| 15 | Abnormality of the labia minora (HP:0012880) | 3.22768736 |
| 16 | Birth length less than 3rd percentile (HP:0003561) | 3.21782700 |
| 17 | Methylmalonic aciduria (HP:0012120) | 3.13172733 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.00573295 |
| 19 | Abnormality of the vocal cords (HP:0008777) | 2.97183246 |
| 20 | Lipid accumulation in hepatocytes (HP:0006561) | 2.95206581 |
| 21 | Colon cancer (HP:0003003) | 2.91835791 |
| 22 | Congenital stationary night blindness (HP:0007642) | 2.75580249 |
| 23 | Respiratory failure (HP:0002878) | 2.74565159 |
| 24 | Respiratory difficulties (HP:0002880) | 2.70812116 |
| 25 | Cerebral hypomyelination (HP:0006808) | 2.70639444 |
| 26 | Lactic acidosis (HP:0003128) | 2.69495822 |
| 27 | CNS demyelination (HP:0007305) | 2.69084529 |
| 28 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.65846975 |
| 29 | Decreased central vision (HP:0007663) | 2.54278921 |
| 30 | Exertional dyspnea (HP:0002875) | 2.50653417 |
| 31 | Increased serum lactate (HP:0002151) | 2.48350078 |
| 32 | Facial diplegia (HP:0001349) | 2.47662190 |
| 33 | Lethargy (HP:0001254) | 2.44631285 |
| 34 | True hermaphroditism (HP:0010459) | 2.43853581 |
| 35 | Leukodystrophy (HP:0002415) | 2.37312702 |
| 36 | Increased intramyocellular lipid droplets (HP:0012240) | 2.37000915 |
| 37 | Abnormality of methionine metabolism (HP:0010901) | 2.36371242 |
| 38 | Nephronophthisis (HP:0000090) | 2.35845507 |
| 39 | Abnormality of serum amino acid levels (HP:0003112) | 2.35112242 |
| 40 | Severe combined immunodeficiency (HP:0004430) | 2.34748466 |
| 41 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.33946735 |
| 42 | Abnormal hair whorl (HP:0010721) | 2.32231908 |
| 43 | Molar tooth sign on MRI (HP:0002419) | 2.25903657 |
| 44 | Abnormality of midbrain morphology (HP:0002418) | 2.25903657 |
| 45 | Sparse eyelashes (HP:0000653) | 2.25029688 |
| 46 | Pancreatic fibrosis (HP:0100732) | 2.24787055 |
| 47 | CNS hypomyelination (HP:0003429) | 2.24782741 |
| 48 | Abnormality of vitamin B metabolism (HP:0004340) | 2.24060561 |
| 49 | Pili torti (HP:0003777) | 2.21916870 |
| 50 | Abnormal number of erythroid precursors (HP:0012131) | 2.18419972 |
| 51 | Abnormality of alanine metabolism (HP:0010916) | 2.17915949 |
| 52 | Hyperalaninemia (HP:0003348) | 2.17915949 |
| 53 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.17915949 |
| 54 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.16598687 |
| 55 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.16529320 |
| 56 | Hyperglycinemia (HP:0002154) | 2.13760324 |
| 57 | Megaloblastic anemia (HP:0001889) | 2.12247266 |
| 58 | Exercise intolerance (HP:0003546) | 2.10551079 |
| 59 | Oral leukoplakia (HP:0002745) | 2.09308579 |
| 60 | Myokymia (HP:0002411) | 2.08763860 |
| 61 | Septo-optic dysplasia (HP:0100842) | 2.06608201 |
| 62 | Hypoplasia of the pons (HP:0012110) | 2.05074118 |
| 63 | Pancreatic cysts (HP:0001737) | 2.03666213 |
| 64 | Optic disc pallor (HP:0000543) | 2.03023073 |
| 65 | Progressive inability to walk (HP:0002505) | 2.02406380 |
| 66 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.99176997 |
| 67 | Cellular immunodeficiency (HP:0005374) | 1.97906649 |
| 68 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.96192540 |
| 69 | Hypoproteinemia (HP:0003075) | 1.95912469 |
| 70 | Combined immunodeficiency (HP:0005387) | 1.95537648 |
| 71 | Abnormal lung lobation (HP:0002101) | 1.93461971 |
| 72 | Supernumerary spleens (HP:0009799) | 1.92612188 |
| 73 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.91947970 |
| 74 | Abnormality of glycine metabolism (HP:0010895) | 1.91947970 |
| 75 | Rough bone trabeculation (HP:0100670) | 1.91803698 |
| 76 | Abolished electroretinogram (ERG) (HP:0000550) | 1.90787832 |
| 77 | Abnormality of the pons (HP:0007361) | 1.90606233 |
| 78 | Carpal bone hypoplasia (HP:0001498) | 1.88407134 |
| 79 | Stenosis of the external auditory canal (HP:0000402) | 1.87939184 |
| 80 | IgG deficiency (HP:0004315) | 1.86451568 |
| 81 | Emotional lability (HP:0000712) | 1.86425698 |
| 82 | Pendular nystagmus (HP:0012043) | 1.83183255 |
| 83 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.82158927 |
| 84 | Stomatitis (HP:0010280) | 1.80956779 |
| 85 | Microvesicular hepatic steatosis (HP:0001414) | 1.80415854 |
| 86 | Macrocytic anemia (HP:0001972) | 1.78853078 |
| 87 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.77360107 |
| 88 | Thyroid-stimulating hormone excess (HP:0002925) | 1.76875934 |
| 89 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.76453645 |
| 90 | X-linked dominant inheritance (HP:0001423) | 1.75361653 |
| 91 | Hip dysplasia (HP:0001385) | 1.75065513 |
| 92 | Panhypogammaglobulinemia (HP:0003139) | 1.74964388 |
| 93 | Abnormality of renal resorption (HP:0011038) | 1.73764881 |
| 94 | Chronic bronchitis (HP:0004469) | 1.73495297 |
| 95 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.73133993 |
| 96 | Abnormality of the renal medulla (HP:0100957) | 1.72789718 |
| 97 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.71877972 |
| 98 | IgM deficiency (HP:0002850) | 1.70517626 |
| 99 | Hyperglycinuria (HP:0003108) | 1.69347793 |
| 100 | Absent septum pellucidum (HP:0001331) | 1.69038206 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PDK2 | 7.61276473 |
| 2 | VRK2 | 4.34895711 |
| 3 | NUAK1 | 3.70654614 |
| 4 | CDC7 | 3.65796603 |
| 5 | LATS1 | 2.85530540 |
| 6 | BUB1 | 2.55543341 |
| 7 | MKNK2 | 2.32322609 |
| 8 | MST4 | 2.17845905 |
| 9 | BMPR1B | 2.10418077 |
| 10 | TNIK | 1.92952195 |
| 11 | NEK6 | 1.92527003 |
| 12 | PLK4 | 1.91227467 |
| 13 | MKNK1 | 1.78813318 |
| 14 | VRK1 | 1.76895451 |
| 15 | BCKDK | 1.72328758 |
| 16 | GRK1 | 1.68656121 |
| 17 | STK16 | 1.67848725 |
| 18 | NME1 | 1.65662956 |
| 19 | PBK | 1.64513349 |
| 20 | ZAK | 1.62830549 |
| 21 | TTK | 1.60941292 |
| 22 | TAF1 | 1.59012705 |
| 23 | WNK3 | 1.58006906 |
| 24 | AKT3 | 1.48823723 |
| 25 | PLK3 | 1.42856148 |
| 26 | MAP4K2 | 1.39965425 |
| 27 | KDR | 1.39534653 |
| 28 | FRK | 1.39180409 |
| 29 | TSSK6 | 1.29811010 |
| 30 | EIF2AK3 | 1.29453541 |
| 31 | ADRBK2 | 1.19005120 |
| 32 | PIK3CA | 1.18133641 |
| 33 | TRIM28 | 1.17665613 |
| 34 | PLK1 | 1.14108630 |
| 35 | SRPK1 | 1.10920619 |
| 36 | NEK1 | 1.10284059 |
| 37 | NTRK2 | 1.06726479 |
| 38 | STK3 | 0.97030189 |
| 39 | IRAK2 | 0.93252639 |
| 40 | TLK1 | 0.89365568 |
| 41 | BRAF | 0.76064113 |
| 42 | PRKCG | 0.73445891 |
| 43 | TIE1 | 0.71698936 |
| 44 | BRSK2 | 0.67742325 |
| 45 | CSNK1G1 | 0.65755640 |
| 46 | OXSR1 | 0.63027693 |
| 47 | DYRK2 | 0.61644771 |
| 48 | IRAK1 | 0.61408119 |
| 49 | PLK2 | 0.60987014 |
| 50 | INSRR | 0.55071391 |
| 51 | MAPK13 | 0.54245881 |
| 52 | CSNK2A2 | 0.54216387 |
| 53 | ATR | 0.53215466 |
| 54 | STK4 | 0.51672131 |
| 55 | GRK7 | 0.49001819 |
| 56 | TXK | 0.46941589 |
| 57 | MAP3K4 | 0.45943359 |
| 58 | CSNK2A1 | 0.44504574 |
| 59 | MAP4K1 | 0.44052310 |
| 60 | RPS6KA4 | 0.43961269 |
| 61 | LIMK1 | 0.43332214 |
| 62 | MAPK7 | 0.43327100 |
| 63 | PHKG1 | 0.43201058 |
| 64 | PHKG2 | 0.43201058 |
| 65 | ATM | 0.43033920 |
| 66 | DAPK1 | 0.42827719 |
| 67 | EIF2AK1 | 0.42600972 |
| 68 | CSNK1E | 0.42440270 |
| 69 | AURKB | 0.41809370 |
| 70 | DYRK3 | 0.41626413 |
| 71 | PRKCE | 0.41268155 |
| 72 | BRD4 | 0.40444272 |
| 73 | MAPKAPK5 | 0.39624283 |
| 74 | PASK | 0.39571893 |
| 75 | ACVR1B | 0.39226206 |
| 76 | ALK | 0.37881250 |
| 77 | NLK | 0.37479891 |
| 78 | CLK1 | 0.36619063 |
| 79 | PTK2B | 0.35855268 |
| 80 | CDK8 | 0.35442296 |
| 81 | CAMK2G | 0.35147594 |
| 82 | PRKACA | 0.34078271 |
| 83 | CHEK2 | 0.33215361 |
| 84 | PRKCI | 0.32793354 |
| 85 | CDK3 | 0.31769532 |
| 86 | CSNK1G2 | 0.30469732 |
| 87 | CDK7 | 0.30217005 |
| 88 | PIM2 | 0.29945565 |
| 89 | EIF2AK2 | 0.29943200 |
| 90 | NEK2 | 0.29525106 |
| 91 | WEE1 | 0.26850156 |
| 92 | BRSK1 | 0.26778002 |
| 93 | TEC | 0.26655902 |
| 94 | CAMK2A | 0.26436594 |
| 95 | CSNK1A1 | 0.25310029 |
| 96 | PRKCA | 0.25085326 |
| 97 | RPS6KA5 | 0.24776937 |
| 98 | TESK2 | 0.24208310 |
| 99 | PRKCQ | 0.23788115 |
| 100 | AURKA | 0.23497524 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.95322452 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.64324224 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.52202741 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.13934276 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.00960448 |
| 6 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.69903874 |
| 7 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.64316503 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.58509042 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.57104321 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.44237477 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.25039749 |
| 12 | DNA replication_Homo sapiens_hsa03030 | 2.18677233 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.07668590 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.03171294 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 1.97426806 |
| 16 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.97022758 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.94772940 |
| 18 | Spliceosome_Homo sapiens_hsa03040 | 1.91972944 |
| 19 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.87773218 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.78248609 |
| 21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71727347 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.69349626 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.67146106 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.62657291 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.55186718 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.50862667 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.43049791 |
| 28 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.38475354 |
| 29 | RNA transport_Homo sapiens_hsa03013 | 1.36555523 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34208388 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.33795305 |
| 32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32230037 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.27811060 |
| 34 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.21069992 |
| 35 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.20356991 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.15106873 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.10178545 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 1.07352868 |
| 39 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.06865546 |
| 40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.05168603 |
| 41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.03245367 |
| 42 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.02437631 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.95703648 |
| 44 | Phototransduction_Homo sapiens_hsa04744 | 0.93884829 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.92674839 |
| 46 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.89450215 |
| 47 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.89043472 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.88960017 |
| 49 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.87854613 |
| 50 | Cell cycle_Homo sapiens_hsa04110 | 0.87226244 |
| 51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.86640700 |
| 52 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86017825 |
| 53 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.84405189 |
| 54 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.82749595 |
| 55 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.79871976 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.76472783 |
| 57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.76314775 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.75674043 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75310026 |
| 60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.73530875 |
| 61 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.72181707 |
| 62 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.70690614 |
| 63 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.68412096 |
| 64 | Carbon metabolism_Homo sapiens_hsa01200 | 0.68138505 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66862619 |
| 66 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.66205322 |
| 67 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.66023767 |
| 68 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.65373548 |
| 69 | Nicotine addiction_Homo sapiens_hsa05033 | 0.64201679 |
| 70 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60598554 |
| 71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.60566337 |
| 72 | Sulfur relay system_Homo sapiens_hsa04122 | 0.56140225 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54895872 |
| 74 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.52354311 |
| 75 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51032151 |
| 76 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.49131246 |
| 77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.48942936 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45663631 |
| 79 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43992352 |
| 80 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.41971095 |
| 81 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.41307434 |
| 82 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39128601 |
| 83 | Lysine degradation_Homo sapiens_hsa00310 | 0.37128921 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.36532730 |
| 85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.32521575 |
| 86 | ABC transporters_Homo sapiens_hsa02010 | 0.30340033 |
| 87 | Taste transduction_Homo sapiens_hsa04742 | 0.28064211 |
| 88 | Mineral absorption_Homo sapiens_hsa04978 | 0.26828898 |
| 89 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.25456068 |
| 90 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.23175013 |
| 91 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.22781010 |
| 92 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.21959848 |
| 93 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.18100045 |
| 94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.17490722 |
| 95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.16271221 |
| 96 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.15952836 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.15825661 |
| 98 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.14796096 |
| 99 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.13496120 |
| 100 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.12734781 |

