

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine metabolic process (GO:0046087) | 7.06766523 |
| 2 | cytidine catabolic process (GO:0006216) | 7.06766523 |
| 3 | cytidine deamination (GO:0009972) | 7.06766523 |
| 4 | DNA deamination (GO:0045006) | 6.96013659 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.99581904 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.74894731 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.49427749 |
| 8 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.46758854 |
| 9 | proteasome assembly (GO:0043248) | 5.42808664 |
| 10 | protein neddylation (GO:0045116) | 5.33673283 |
| 11 | chaperone-mediated protein transport (GO:0072321) | 5.03445149 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.82481241 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.82481241 |
| 14 | chromatin remodeling at centromere (GO:0031055) | 4.28481951 |
| 15 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.23259240 |
| 16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.18416827 |
| 17 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.16623392 |
| 18 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.15138336 |
| 19 | termination of RNA polymerase III transcription (GO:0006386) | 4.15138336 |
| 20 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.09547833 |
| 21 | CENP-A containing nucleosome assembly (GO:0034080) | 4.07736059 |
| 22 | respiratory electron transport chain (GO:0022904) | 4.04254694 |
| 23 | negative regulation of T cell apoptotic process (GO:0070233) | 4.03488463 |
| 24 | sequestering of actin monomers (GO:0042989) | 4.00801420 |
| 25 | electron transport chain (GO:0022900) | 3.98162681 |
| 26 | cullin deneddylation (GO:0010388) | 3.95752275 |
| 27 | cytolysis (GO:0019835) | 3.88278490 |
| 28 | protein deneddylation (GO:0000338) | 3.86620742 |
| 29 | negative regulation of ligase activity (GO:0051352) | 3.82119777 |
| 30 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.82119777 |
| 31 | ribosome assembly (GO:0042255) | 3.80197829 |
| 32 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.74818315 |
| 33 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.74818315 |
| 34 | DNA double-strand break processing (GO:0000729) | 3.74777155 |
| 35 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.66455215 |
| 36 | pseudouridine synthesis (GO:0001522) | 3.60576688 |
| 37 | respiratory chain complex IV assembly (GO:0008535) | 3.60116677 |
| 38 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.57610313 |
| 39 | histone exchange (GO:0043486) | 3.56920006 |
| 40 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.55367567 |
| 41 | metallo-sulfur cluster assembly (GO:0031163) | 3.54687268 |
| 42 | iron-sulfur cluster assembly (GO:0016226) | 3.54687268 |
| 43 | histone mRNA metabolic process (GO:0008334) | 3.49639315 |
| 44 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.31310623 |
| 45 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.30739635 |
| 46 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.25541579 |
| 47 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.16338159 |
| 48 | cytochrome complex assembly (GO:0017004) | 3.14993712 |
| 49 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.14105621 |
| 50 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.14105621 |
| 51 | protein targeting to mitochondrion (GO:0006626) | 3.11505081 |
| 52 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.09792378 |
| 53 | DNA demethylation (GO:0080111) | 3.08062767 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.07906830 |
| 55 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.07906830 |
| 56 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.07906830 |
| 57 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.07378738 |
| 58 | rRNA modification (GO:0000154) | 3.04363946 |
| 59 | negative regulation of sister chromatid segregation (GO:0033046) | 3.03977094 |
| 60 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.03977094 |
| 61 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.03977094 |
| 62 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.03977094 |
| 63 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.03977094 |
| 64 | eosinophil chemotaxis (GO:0048245) | 3.03180920 |
| 65 | positive T cell selection (GO:0043368) | 3.01596240 |
| 66 | negative regulation by host of viral transcription (GO:0043922) | 3.01317096 |
| 67 | establishment of protein localization to mitochondrion (GO:0072655) | 3.00891276 |
| 68 | protein K11-linked ubiquitination (GO:0070979) | 2.99803278 |
| 69 | transcription from mitochondrial promoter (GO:0006390) | 2.99386603 |
| 70 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.98159383 |
| 71 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.98159383 |
| 72 | maturation of 5.8S rRNA (GO:0000460) | 2.98101287 |
| 73 | DNA replication-independent nucleosome organization (GO:0034724) | 2.97699197 |
| 74 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.97699197 |
| 75 | negative regulation of telomerase activity (GO:0051974) | 2.97374435 |
| 76 | platelet dense granule organization (GO:0060155) | 2.95734835 |
| 77 | inner mitochondrial membrane organization (GO:0007007) | 2.94968852 |
| 78 | positive regulation of ligase activity (GO:0051351) | 2.94225492 |
| 79 | protein-cofactor linkage (GO:0018065) | 2.93677866 |
| 80 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.92986150 |
| 81 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.92986150 |
| 82 | rRNA catabolic process (GO:0016075) | 2.92933807 |
| 83 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.92850066 |
| 84 | ATP biosynthetic process (GO:0006754) | 2.92337847 |
| 85 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.90917892 |
| 86 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.90301685 |
| 87 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.89159372 |
| 88 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.89159372 |
| 89 | negative regulation of chromosome segregation (GO:0051985) | 2.87741754 |
| 90 | protein complex biogenesis (GO:0070271) | 2.85760323 |
| 91 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.85096759 |
| 92 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.84780868 |
| 93 | ncRNA catabolic process (GO:0034661) | 2.79682147 |
| 94 | mitotic spindle assembly checkpoint (GO:0007094) | 2.78904100 |
| 95 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.78060316 |
| 96 | eosinophil migration (GO:0072677) | 2.76019921 |
| 97 | negative regulation of viral genome replication (GO:0045071) | 2.75067104 |
| 98 | mitotic spindle checkpoint (GO:0071174) | 2.74861963 |
| 99 | protein localization to mitochondrion (GO:0070585) | 2.74218256 |
| 100 | ncRNA 3-end processing (GO:0043628) | 2.73927742 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.26757324 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.29774276 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.83228871 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.61653496 |
| 5 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.13250196 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.00888161 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.98130987 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.85353068 |
| 9 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.65643887 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.63119291 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.60712868 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.59562725 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55495305 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.44642738 |
| 15 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.42572322 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.28428019 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.18170715 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12991452 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.09436639 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.06576253 |
| 21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.93863288 |
| 22 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.88437909 |
| 23 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.81489986 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.81130380 |
| 25 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.78456130 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.73385926 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73238168 |
| 28 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.72241354 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.69088113 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.68095568 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.66363435 |
| 32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.65084881 |
| 33 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.58375295 |
| 34 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.55541162 |
| 35 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.54080740 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.52650988 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.50326982 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.45244406 |
| 39 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.44413367 |
| 40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.41664756 |
| 41 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.41060518 |
| 42 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39491847 |
| 43 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39342185 |
| 44 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.38614404 |
| 45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.36419727 |
| 46 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.34765664 |
| 47 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.32290266 |
| 48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.30970419 |
| 49 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.30818320 |
| 50 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.30632496 |
| 51 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.28446775 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.26054619 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.24716880 |
| 54 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.20920785 |
| 55 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20752842 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20617030 |
| 57 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.19921745 |
| 58 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.19878166 |
| 59 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.19878166 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.18742034 |
| 61 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.17955665 |
| 62 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.17877380 |
| 63 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.17753741 |
| 64 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.17162437 |
| 65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.17162437 |
| 66 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16899182 |
| 67 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.15880733 |
| 68 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.15123364 |
| 69 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.14253277 |
| 70 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.11951804 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.11951804 |
| 72 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.11271321 |
| 73 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.10324530 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09958697 |
| 75 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.07308220 |
| 76 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.06319946 |
| 77 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03079816 |
| 78 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.00763284 |
| 79 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.00591970 |
| 80 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00075644 |
| 81 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.00031910 |
| 82 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99771633 |
| 83 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.99167149 |
| 84 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.97774751 |
| 85 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.97201154 |
| 86 | AR_20517297_ChIP-Seq_VCAP_Human | 0.96536244 |
| 87 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.96315424 |
| 88 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.94009900 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.93826919 |
| 90 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.92683343 |
| 91 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.92600338 |
| 92 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92556036 |
| 93 | MYB_26560356_Chip-Seq_TH2_Human | 0.92460094 |
| 94 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.91817795 |
| 95 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.91697621 |
| 96 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.91121356 |
| 97 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.89838077 |
| 98 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.88939081 |
| 99 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.85860833 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85783827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001188_hyperpigmentation | 4.55331603 |
| 2 | MP0003941_abnormal_skin_development | 4.33548139 |
| 3 | MP0005671_abnormal_response_to | 3.54439637 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.00168755 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.71169390 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.62954283 |
| 7 | MP0005377_hearing/vestibular/ear_phenot | 2.52243968 |
| 8 | MP0003878_abnormal_ear_physiology | 2.52243968 |
| 9 | MP0003786_premature_aging | 2.45443867 |
| 10 | MP0001485_abnormal_pinna_reflex | 2.18351078 |
| 11 | MP0004957_abnormal_blastocyst_morpholog | 2.16363299 |
| 12 | MP0003646_muscle_fatigue | 2.16288560 |
| 13 | MP0002277_abnormal_respiratory_mucosa | 2.15344380 |
| 14 | MP0003693_abnormal_embryo_hatching | 2.12060857 |
| 15 | MP0002102_abnormal_ear_morphology | 2.00488974 |
| 16 | MP0003136_yellow_coat_color | 1.94074395 |
| 17 | MP0002736_abnormal_nociception_after | 1.90146600 |
| 18 | MP0008007_abnormal_cellular_replicative | 1.82696941 |
| 19 | MP0006035_abnormal_mitochondrial_morpho | 1.73115241 |
| 20 | MP0001873_stomach_inflammation | 1.72526351 |
| 21 | MP0003448_altered_tumor_morphology | 1.71862587 |
| 22 | MP0002933_joint_inflammation | 1.69339807 |
| 23 | MP0003567_abnormal_fetal_cardiomyocyte | 1.69313000 |
| 24 | MP0009785_altered_susceptibility_to | 1.64566733 |
| 25 | MP0003111_abnormal_nucleus_morphology | 1.60011678 |
| 26 | MP0004147_increased_porphyrin_level | 1.59550346 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.53861875 |
| 28 | MP0008872_abnormal_physiological_respon | 1.53654134 |
| 29 | MP0010094_abnormal_chromosome_stability | 1.47969985 |
| 30 | MP0000579_abnormal_nail_morphology | 1.46500930 |
| 31 | MP0003137_abnormal_impulse_conducting | 1.44542702 |
| 32 | MP0006036_abnormal_mitochondrial_physio | 1.43886355 |
| 33 | MP0005084_abnormal_gallbladder_morpholo | 1.35798259 |
| 34 | MP0005253_abnormal_eye_physiology | 1.35654566 |
| 35 | MP0005083_abnormal_biliary_tract | 1.33888729 |
| 36 | MP0001661_extended_life_span | 1.32885728 |
| 37 | MP0008932_abnormal_embryonic_tissue | 1.32050205 |
| 38 | MP0003763_abnormal_thymus_physiology | 1.31977442 |
| 39 | MP0001968_abnormal_touch/_nociception | 1.28568334 |
| 40 | MP0009379_abnormal_foot_pigmentation | 1.28538900 |
| 41 | MP0004134_abnormal_chest_morphology | 1.27277675 |
| 42 | MP0003938_abnormal_ear_development | 1.25682778 |
| 43 | MP0003806_abnormal_nucleotide_metabolis | 1.25052543 |
| 44 | MP0009333_abnormal_splenocyte_physiolog | 1.21480039 |
| 45 | MP0003195_calcinosis | 1.20801571 |
| 46 | MP0008789_abnormal_olfactory_epithelium | 1.14201564 |
| 47 | MP0001984_abnormal_olfaction | 1.13288314 |
| 48 | MP0003718_maternal_effect | 1.10640746 |
| 49 | MP0005645_abnormal_hypothalamus_physiol | 1.09652891 |
| 50 | MP0001529_abnormal_vocalization | 1.06678646 |
| 51 | MP0000703_abnormal_thymus_morphology | 1.06157976 |
| 52 | MP0000647_abnormal_sebaceous_gland | 1.05194604 |
| 53 | MP0002138_abnormal_hepatobiliary_system | 1.01438598 |
| 54 | MP0001542_abnormal_bone_strength | 1.00770698 |
| 55 | MP0008995_early_reproductive_senescence | 1.00375615 |
| 56 | MP0000467_abnormal_esophagus_morphology | 1.00346837 |
| 57 | MP0003119_abnormal_digestive_system | 0.98868249 |
| 58 | MP0001293_anophthalmia | 0.97998832 |
| 59 | MP0000689_abnormal_spleen_morphology | 0.97917177 |
| 60 | MP0008058_abnormal_DNA_repair | 0.96644649 |
| 61 | MP0001919_abnormal_reproductive_system | 0.96602860 |
| 62 | MP0003787_abnormal_imprinting | 0.96506486 |
| 63 | MP0002420_abnormal_adaptive_immunity | 0.92739679 |
| 64 | MP0004885_abnormal_endolymph | 0.91034916 |
| 65 | MP0002722_abnormal_immune_system | 0.89550731 |
| 66 | MP0005389_reproductive_system_phenotype | 0.89075898 |
| 67 | MP0008875_abnormal_xenobiotic_pharmacok | 0.88649193 |
| 68 | MP0000049_abnormal_middle_ear | 0.87891070 |
| 69 | MP0001819_abnormal_immune_cell | 0.87081256 |
| 70 | MP0001800_abnormal_humoral_immune | 0.85021518 |
| 71 | MP0006082_CNS_inflammation | 0.84794545 |
| 72 | MP0003011_delayed_dark_adaptation | 0.84374136 |
| 73 | MP0004145_abnormal_muscle_electrophysio | 0.83218116 |
| 74 | MP0002006_tumorigenesis | 0.82931645 |
| 75 | MP0004215_abnormal_myocardial_fiber | 0.82546614 |
| 76 | MP0005551_abnormal_eye_electrophysiolog | 0.80523551 |
| 77 | MP0005000_abnormal_immune_tolerance | 0.80429167 |
| 78 | MP0001764_abnormal_homeostasis | 0.78677310 |
| 79 | MP0001119_abnormal_female_reproductive | 0.76777064 |
| 80 | MP0000716_abnormal_immune_system | 0.76220225 |
| 81 | MP0001835_abnormal_antigen_presentation | 0.75469272 |
| 82 | MP0004742_abnormal_vestibular_system | 0.75168997 |
| 83 | MP0003077_abnormal_cell_cycle | 0.74968459 |
| 84 | MP0009763_increased_sensitivity_to | 0.74677571 |
| 85 | MP0002398_abnormal_bone_marrow | 0.73685191 |
| 86 | MP0002723_abnormal_immune_serum | 0.73280062 |
| 87 | MP0009745_abnormal_behavioral_response | 0.72129621 |
| 88 | MP0003880_abnormal_central_pattern | 0.70381519 |
| 89 | MP0005410_abnormal_fertilization | 0.69897628 |
| 90 | MP0003866_abnormal_defecation | 0.69826001 |
| 91 | MP0001145_abnormal_male_reproductive | 0.67330633 |
| 92 | MP0002166_altered_tumor_susceptibility | 0.64869151 |
| 93 | MP0002751_abnormal_autonomic_nervous | 0.62988433 |
| 94 | MP0000653_abnormal_sex_gland | 0.62717842 |
| 95 | MP0002148_abnormal_hypersensitivity_rea | 0.62690247 |
| 96 | MP0002909_abnormal_adrenal_gland | 0.62409195 |
| 97 | MP0002429_abnormal_blood_cell | 0.60809166 |
| 98 | MP0002210_abnormal_sex_determination | 0.60415483 |
| 99 | MP0005025_abnormal_response_to | 0.59435679 |
| 100 | MP0005636_abnormal_mineral_homeostasis | 0.59431172 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.72087759 |
| 2 | Mitochondrial inheritance (HP:0001427) | 3.96811261 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.93188737 |
| 4 | Acute encephalopathy (HP:0006846) | 3.81791829 |
| 5 | Hyperglycinemia (HP:0002154) | 3.64317044 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.59052634 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.54474318 |
| 8 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.50098753 |
| 9 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.50098753 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.30581133 |
| 11 | Increased CSF lactate (HP:0002490) | 3.22299281 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.21498449 |
| 13 | Cerebral edema (HP:0002181) | 3.16922043 |
| 14 | Confusion (HP:0001289) | 3.04360407 |
| 15 | Rib fusion (HP:0000902) | 3.01245752 |
| 16 | Increased intramyocellular lipid droplets (HP:0012240) | 2.95502603 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 2.93409462 |
| 18 | Methylmalonic aciduria (HP:0012120) | 2.88771125 |
| 19 | Abnormal number of erythroid precursors (HP:0012131) | 2.86392322 |
| 20 | Hepatocellular necrosis (HP:0001404) | 2.81770735 |
| 21 | Abnormality of glycine metabolism (HP:0010895) | 2.78059556 |
| 22 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.78059556 |
| 23 | True hermaphroditism (HP:0010459) | 2.77563449 |
| 24 | Decreased central vision (HP:0007663) | 2.77480163 |
| 25 | Renal Fanconi syndrome (HP:0001994) | 2.76132312 |
| 26 | Septo-optic dysplasia (HP:0100842) | 2.74552085 |
| 27 | Hypoproteinemia (HP:0003075) | 2.73194151 |
| 28 | IgG deficiency (HP:0004315) | 2.72574629 |
| 29 | Abnormality of the labia minora (HP:0012880) | 2.68600007 |
| 30 | Abnormality of serum amino acid levels (HP:0003112) | 2.68248970 |
| 31 | Methylmalonic acidemia (HP:0002912) | 2.61412746 |
| 32 | Molar tooth sign on MRI (HP:0002419) | 2.61373106 |
| 33 | Abnormality of midbrain morphology (HP:0002418) | 2.61373106 |
| 34 | Pancytopenia (HP:0001876) | 2.60805034 |
| 35 | Lethargy (HP:0001254) | 2.59511244 |
| 36 | Severe combined immunodeficiency (HP:0004430) | 2.57920969 |
| 37 | Pendular nystagmus (HP:0012043) | 2.50127683 |
| 38 | Abolished electroretinogram (ERG) (HP:0000550) | 2.49681913 |
| 39 | Colon cancer (HP:0003003) | 2.49279973 |
| 40 | Pancreatic fibrosis (HP:0100732) | 2.45954480 |
| 41 | Lactic acidosis (HP:0003128) | 2.42230641 |
| 42 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.38459101 |
| 43 | Increased serum lactate (HP:0002151) | 2.34585777 |
| 44 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.33495755 |
| 45 | IgM deficiency (HP:0002850) | 2.29844687 |
| 46 | Pancreatic cysts (HP:0001737) | 2.28128069 |
| 47 | Hyperglycinuria (HP:0003108) | 2.27704111 |
| 48 | Stenosis of the external auditory canal (HP:0000402) | 2.24751932 |
| 49 | Hepatic necrosis (HP:0002605) | 2.19409515 |
| 50 | Oral leukoplakia (HP:0002745) | 2.18450376 |
| 51 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.17903757 |
| 52 | Combined immunodeficiency (HP:0005387) | 2.16098109 |
| 53 | Amniotic constriction ring (HP:0009775) | 2.14310446 |
| 54 | Abnormality of placental membranes (HP:0011409) | 2.14310446 |
| 55 | Lymphopenia (HP:0001888) | 2.13837872 |
| 56 | Bile duct proliferation (HP:0001408) | 2.12723740 |
| 57 | Abnormal biliary tract physiology (HP:0012439) | 2.12723740 |
| 58 | Increased muscle lipid content (HP:0009058) | 2.12499546 |
| 59 | Exertional dyspnea (HP:0002875) | 2.10338475 |
| 60 | Exercise intolerance (HP:0003546) | 2.09651963 |
| 61 | Hypoplasia of the thymus (HP:0000778) | 2.09572130 |
| 62 | Anomalous pulmonary venous return (HP:0010772) | 2.09057019 |
| 63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.07487638 |
| 64 | Respiratory failure (HP:0002878) | 2.03516388 |
| 65 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.03430417 |
| 66 | Thyroiditis (HP:0100646) | 2.03422667 |
| 67 | Anencephaly (HP:0002323) | 2.02186265 |
| 68 | Panhypogammaglobulinemia (HP:0003139) | 2.01992093 |
| 69 | Optic disc pallor (HP:0000543) | 2.01622489 |
| 70 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.99535610 |
| 71 | Respiratory difficulties (HP:0002880) | 1.93126880 |
| 72 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.91289643 |
| 73 | Esophageal atresia (HP:0002032) | 1.88436141 |
| 74 | Congenital stationary night blindness (HP:0007642) | 1.88126498 |
| 75 | Limb hypertonia (HP:0002509) | 1.87868895 |
| 76 | Absent septum pellucidum (HP:0001331) | 1.86249315 |
| 77 | Abnormal lung lobation (HP:0002101) | 1.86183308 |
| 78 | Hypoplasia of the pons (HP:0012110) | 1.85626452 |
| 79 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.83665180 |
| 80 | Abnormal number of incisors (HP:0011064) | 1.83443029 |
| 81 | Congenital, generalized hypertrichosis (HP:0004540) | 1.82918579 |
| 82 | Abnormality of the pulmonary veins (HP:0011718) | 1.81042647 |
| 83 | Leukodystrophy (HP:0002415) | 1.80003804 |
| 84 | Patellar aplasia (HP:0006443) | 1.79678364 |
| 85 | Bifid tongue (HP:0010297) | 1.79312518 |
| 86 | Meckel diverticulum (HP:0002245) | 1.78725588 |
| 87 | Fused cervical vertebrae (HP:0002949) | 1.78469451 |
| 88 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.77278746 |
| 89 | Abnormality of alanine metabolism (HP:0010916) | 1.77278746 |
| 90 | Hyperalaninemia (HP:0003348) | 1.77278746 |
| 91 | Encephalitis (HP:0002383) | 1.75967205 |
| 92 | Erythroderma (HP:0001019) | 1.75615222 |
| 93 | Autoimmune hemolytic anemia (HP:0001890) | 1.75371863 |
| 94 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.72145003 |
| 95 | Cellular immunodeficiency (HP:0005374) | 1.70988861 |
| 96 | Abnormality of eosinophils (HP:0001879) | 1.70393318 |
| 97 | Absent radius (HP:0003974) | 1.69663483 |
| 98 | Attenuation of retinal blood vessels (HP:0007843) | 1.69406061 |
| 99 | Abnormality of renal resorption (HP:0011038) | 1.69403280 |
| 100 | Absent thumb (HP:0009777) | 1.69178019 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 4.41649049 |
| 2 | TRIM28 | 3.91565731 |
| 3 | BUB1 | 3.73162430 |
| 4 | KDR | 3.42375334 |
| 5 | TXK | 3.26436715 |
| 6 | ZAK | 3.16158077 |
| 7 | VRK2 | 2.77668647 |
| 8 | EIF2AK3 | 2.70489180 |
| 9 | MAP4K2 | 2.53599184 |
| 10 | MKNK2 | 2.26619937 |
| 11 | NUAK1 | 2.18037285 |
| 12 | ACVR1B | 2.10643486 |
| 13 | ADRBK2 | 2.08393612 |
| 14 | STK16 | 1.99360516 |
| 15 | SRPK1 | 1.89265214 |
| 16 | PLK4 | 1.86096948 |
| 17 | CDC7 | 1.84336824 |
| 18 | WNK3 | 1.83232276 |
| 19 | OXSR1 | 1.77267852 |
| 20 | BMPR1B | 1.68110087 |
| 21 | BCKDK | 1.66665596 |
| 22 | MKNK1 | 1.49711976 |
| 23 | PLK3 | 1.40832752 |
| 24 | EIF2AK1 | 1.33078785 |
| 25 | VRK1 | 1.31012729 |
| 26 | TTK | 1.29444042 |
| 27 | STK38L | 1.29428485 |
| 28 | FRK | 1.26488379 |
| 29 | GRK1 | 1.26199463 |
| 30 | CDK19 | 1.23847047 |
| 31 | STK39 | 1.21856669 |
| 32 | PLK2 | 1.20608077 |
| 33 | TESK2 | 1.12633936 |
| 34 | PIK3CA | 1.10159771 |
| 35 | TNIK | 1.09981328 |
| 36 | TIE1 | 1.09886668 |
| 37 | MAP4K1 | 1.03955315 |
| 38 | PLK1 | 1.02876710 |
| 39 | DYRK2 | 1.01968545 |
| 40 | EPHA4 | 1.00520568 |
| 41 | MAP3K12 | 1.00113927 |
| 42 | PBK | 0.88765106 |
| 43 | ITK | 0.87510546 |
| 44 | NME1 | 0.83806763 |
| 45 | GRK7 | 0.81799664 |
| 46 | ATR | 0.77227040 |
| 47 | EIF2AK2 | 0.73407684 |
| 48 | NEK1 | 0.72528430 |
| 49 | TAF1 | 0.71168662 |
| 50 | ZAP70 | 0.70924527 |
| 51 | INSRR | 0.68633163 |
| 52 | CSNK1G1 | 0.68611372 |
| 53 | BCR | 0.62976943 |
| 54 | TSSK6 | 0.62019535 |
| 55 | CSNK2A1 | 0.55875245 |
| 56 | TEC | 0.55775453 |
| 57 | AURKB | 0.53198439 |
| 58 | NLK | 0.52698427 |
| 59 | SYK | 0.52689791 |
| 60 | FES | 0.52250298 |
| 61 | FGFR2 | 0.51207680 |
| 62 | MAP3K11 | 0.50609564 |
| 63 | OBSCN | 0.50141135 |
| 64 | CSNK1G3 | 0.48143745 |
| 65 | CSNK2A2 | 0.48106643 |
| 66 | CSF1R | 0.47727105 |
| 67 | WNK4 | 0.46377228 |
| 68 | LCK | 0.45330383 |
| 69 | BTK | 0.44376064 |
| 70 | RPS6KA5 | 0.44186868 |
| 71 | PRKCQ | 0.42996136 |
| 72 | MELK | 0.42602581 |
| 73 | CSNK1G2 | 0.42438207 |
| 74 | CSK | 0.41340032 |
| 75 | IKBKB | 0.40783592 |
| 76 | LYN | 0.40753304 |
| 77 | TAOK3 | 0.40644748 |
| 78 | MAP3K5 | 0.40591360 |
| 79 | PRKCE | 0.39436503 |
| 80 | CSNK1A1 | 0.39388745 |
| 81 | ERBB3 | 0.38862950 |
| 82 | MYLK | 0.37738199 |
| 83 | ATM | 0.37158794 |
| 84 | PIM1 | 0.35951539 |
| 85 | ADRBK1 | 0.35712931 |
| 86 | INSR | 0.34002959 |
| 87 | DYRK3 | 0.32713403 |
| 88 | AURKA | 0.32542081 |
| 89 | NME2 | 0.31146723 |
| 90 | PRKCG | 0.30934671 |
| 91 | LIMK1 | 0.30795827 |
| 92 | ROCK1 | 0.30778536 |
| 93 | TYRO3 | 0.30503847 |
| 94 | PRKCA | 0.30347639 |
| 95 | IGF1R | 0.29351222 |
| 96 | PAK4 | 0.29071908 |
| 97 | BRD4 | 0.28330897 |
| 98 | CSNK1A1L | 0.28319622 |
| 99 | TGFBR1 | 0.28035851 |
| 100 | RPS6KA4 | 0.27925624 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.83761255 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.75652553 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.48023369 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.33234348 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.68017440 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.63663591 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.60197936 |
| 8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.33514829 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.22076512 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.15014987 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.12515697 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.12044437 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.11188311 |
| 14 | Spliceosome_Homo sapiens_hsa03040 | 1.99873821 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.87304457 |
| 16 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.81084095 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.74911593 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.73536088 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.71541538 |
| 20 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.62996032 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.62209465 |
| 22 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.61896768 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.61128791 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.54426783 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.50455126 |
| 26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.47535893 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.43360666 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.36893724 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.32367348 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.30653291 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.25800511 |
| 32 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.21683273 |
| 33 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.21654348 |
| 34 | Purine metabolism_Homo sapiens_hsa00230 | 1.15413939 |
| 35 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.14388416 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.11455773 |
| 37 | Allograft rejection_Homo sapiens_hsa05330 | 1.10221308 |
| 38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.05687016 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.05201120 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.04922340 |
| 41 | Phototransduction_Homo sapiens_hsa04744 | 1.03798783 |
| 42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.02304149 |
| 43 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.00598980 |
| 44 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.00051578 |
| 45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.95598450 |
| 46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.90476896 |
| 47 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.89397714 |
| 48 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.84488101 |
| 49 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.81711731 |
| 50 | Cell cycle_Homo sapiens_hsa04110 | 0.79172570 |
| 51 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.78857391 |
| 52 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.78210243 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74867743 |
| 54 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72336553 |
| 55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.72152052 |
| 56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70839660 |
| 57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68808008 |
| 58 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.67609029 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.66697519 |
| 60 | Salmonella infection_Homo sapiens_hsa05132 | 0.63972886 |
| 61 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.63099522 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62074817 |
| 63 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.62021135 |
| 64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.59173260 |
| 65 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.57293989 |
| 66 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56821395 |
| 67 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52700320 |
| 68 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.51597784 |
| 69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51438151 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51309703 |
| 71 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.50619111 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47635154 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.46081142 |
| 74 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.45759936 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45223374 |
| 76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.45013583 |
| 77 | Base excision repair_Homo sapiens_hsa03410 | 0.44656120 |
| 78 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.44452853 |
| 79 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.43840003 |
| 80 | Carbon metabolism_Homo sapiens_hsa01200 | 0.43769066 |
| 81 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.43201863 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42538325 |
| 83 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.42177401 |
| 84 | Nicotine addiction_Homo sapiens_hsa05033 | 0.41833265 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40811558 |
| 86 | Asthma_Homo sapiens_hsa05310 | 0.40226704 |
| 87 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.37969519 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.35793227 |
| 89 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.34788449 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.34195450 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32996727 |
| 92 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.32082250 |
| 93 | Sulfur relay system_Homo sapiens_hsa04122 | 0.32039091 |
| 94 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.30826084 |
| 95 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.30526617 |
| 96 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.28976899 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27970998 |
| 98 | Measles_Homo sapiens_hsa05162 | 0.27048934 |
| 99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26979211 |
| 100 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.26513910 |

