Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.75528959 |
2 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.75528959 |
3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.73119857 |
4 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.15072591 |
5 | * positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.11659616 |
6 | ribosomal small subunit assembly (GO:0000028) | 5.10083513 |
7 | negative T cell selection (GO:0043383) | 4.96969131 |
8 | interferon-gamma production (GO:0032609) | 4.94939359 |
9 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.82093750 |
10 | negative thymic T cell selection (GO:0045060) | 4.79070059 |
11 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.57637303 |
12 | positive thymic T cell selection (GO:0045059) | 4.49027531 |
13 | mast cell activation (GO:0045576) | 4.40094912 |
14 | regulation of gamma-delta T cell activation (GO:0046643) | 4.34726148 |
15 | response to interleukin-15 (GO:0070672) | 4.28715568 |
16 | cellular response to interleukin-15 (GO:0071350) | 4.25155820 |
17 | DNA deamination (GO:0045006) | 4.16557403 |
18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.04361775 |
19 | thymic T cell selection (GO:0045061) | 4.00969379 |
20 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.00214704 |
21 | positive T cell selection (GO:0043368) | 3.99982688 |
22 | regulation of B cell differentiation (GO:0045577) | 3.91979235 |
23 | leukocyte aggregation (GO:0070486) | 3.87927735 |
24 | T cell selection (GO:0045058) | 3.87547968 |
25 | viral transcription (GO:0019083) | 3.85147787 |
26 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.80166573 |
27 | Peyers patch development (GO:0048541) | 3.80166573 |
28 | T cell migration (GO:0072678) | 3.77659618 |
29 | B cell receptor signaling pathway (GO:0050853) | 3.76212885 |
30 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.75146660 |
31 | negative regulation of cell killing (GO:0031342) | 3.75146660 |
32 | negative regulation of T cell mediated immunity (GO:0002710) | 3.72811856 |
33 | activated T cell proliferation (GO:0050798) | 3.71753011 |
34 | T cell receptor signaling pathway (GO:0050852) | 3.71613727 |
35 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.70977069 |
36 | translational termination (GO:0006415) | 3.67445539 |
37 | positive regulation of B cell differentiation (GO:0045579) | 3.66817010 |
38 | positive regulation of T cell cytokine production (GO:0002726) | 3.66528997 |
39 | * regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.65276547 |
40 | mast cell degranulation (GO:0043303) | 3.61884926 |
41 | mast cell activation involved in immune response (GO:0002279) | 3.61884926 |
42 | T cell homeostasis (GO:0043029) | 3.60582607 |
43 | * regulation of T cell receptor signaling pathway (GO:0050856) | 3.55191595 |
44 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.53457276 |
45 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.45551508 |
46 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.43904739 |
47 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.42739633 |
48 | T cell costimulation (GO:0031295) | 3.40735525 |
49 | ribosomal small subunit biogenesis (GO:0042274) | 3.36935760 |
50 | lymphocyte costimulation (GO:0031294) | 3.36059418 |
51 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.34594247 |
52 | cellular response to interferon-beta (GO:0035458) | 3.30361816 |
53 | negative regulation of phagocytosis (GO:0050765) | 3.26180510 |
54 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.25044368 |
55 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.24456241 |
56 | translational elongation (GO:0006414) | 3.23361435 |
57 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.22654836 |
58 | response to type I interferon (GO:0034340) | 3.20054255 |
59 | synaptic vesicle maturation (GO:0016188) | 3.19092144 |
60 | cellular response to type I interferon (GO:0071357) | 3.17570418 |
61 | type I interferon signaling pathway (GO:0060337) | 3.17570418 |
62 | cotranslational protein targeting to membrane (GO:0006613) | 3.16973493 |
63 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.14458654 |
64 | protein targeting to ER (GO:0045047) | 3.14381765 |
65 | regulation of T cell tolerance induction (GO:0002664) | 3.14326537 |
66 | regulation of T cell cytokine production (GO:0002724) | 3.14284769 |
67 | positive regulation of isotype switching (GO:0045830) | 3.13930787 |
68 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.13109366 |
69 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.12437648 |
70 | cytidine deamination (GO:0009972) | 3.12215554 |
71 | cytidine metabolic process (GO:0046087) | 3.12215554 |
72 | cytidine catabolic process (GO:0006216) | 3.12215554 |
73 | cellular response to zinc ion (GO:0071294) | 3.11859681 |
74 | regulation of response to interferon-gamma (GO:0060330) | 3.10575801 |
75 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.09577298 |
76 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.09051557 |
77 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.08142219 |
78 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.08141579 |
79 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.07710501 |
80 | dendritic cell chemotaxis (GO:0002407) | 3.07368944 |
81 | regulation of granulocyte differentiation (GO:0030852) | 3.02132080 |
82 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.00815249 |
83 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.00688129 |
84 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.00470798 |
85 | regulation of alpha-beta T cell activation (GO:0046634) | 2.99759975 |
86 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.99715690 |
87 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.99715690 |
88 | lymphocyte homeostasis (GO:0002260) | 2.99601422 |
89 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.99106794 |
90 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.99089860 |
91 | protein localization to endoplasmic reticulum (GO:0070972) | 2.97809619 |
92 | regulation of regulatory T cell differentiation (GO:0045589) | 2.96964486 |
93 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.95953752 |
94 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.95449365 |
95 | positive regulation of interleukin-4 production (GO:0032753) | 2.94472578 |
96 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.94260863 |
97 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.94184689 |
98 | T cell differentiation (GO:0030217) | 2.93938895 |
99 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.91474529 |
100 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.91474529 |
101 | positive regulation of granulocyte differentiation (GO:0030854) | 2.91367528 |
102 | regulation of interleukin-2 production (GO:0032663) | 2.90802207 |
103 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.88948495 |
104 | DNA strand elongation (GO:0022616) | 2.88266107 |
105 | sleep (GO:0030431) | 2.87319125 |
106 | maturation of SSU-rRNA (GO:0030490) | 2.85935682 |
107 | regulation of isotype switching (GO:0045191) | 2.83996221 |
108 | immunoglobulin mediated immune response (GO:0016064) | 2.83487289 |
109 | viral life cycle (GO:0019058) | 2.83318464 |
110 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.82495644 |
111 | signal complex assembly (GO:0007172) | 2.82275867 |
112 | positive regulation of interleukin-2 production (GO:0032743) | 2.81566505 |
113 | V(D)J recombination (GO:0033151) | 2.81168134 |
114 | NIK/NF-kappaB signaling (GO:0038061) | 2.79320595 |
115 | lymphoid progenitor cell differentiation (GO:0002320) | 2.78683969 |
116 | cellular protein complex disassembly (GO:0043624) | 2.78565684 |
117 | lymph node development (GO:0048535) | 2.78335865 |
118 | defense response to protozoan (GO:0042832) | 2.78204985 |
119 | response to protozoan (GO:0001562) | 2.78178364 |
120 | regulation of B cell mediated immunity (GO:0002712) | 2.78076063 |
121 | leukocyte homeostasis (GO:0001776) | 2.77904414 |
122 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.76207384 |
123 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.76098591 |
124 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 2.75134961 |
125 | regulation of T cell mediated immunity (GO:0002709) | 2.74589572 |
126 | positive regulation of DNA recombination (GO:0045911) | 2.74162768 |
127 | alpha-beta T cell differentiation (GO:0046632) | 2.74149321 |
128 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.74055393 |
129 | T cell activation (GO:0042110) | 2.74040075 |
130 | negative regulation of adaptive immune response (GO:0002820) | 2.73926342 |
131 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.73787466 |
132 | positive regulation of immunoglobulin production (GO:0002639) | 2.72802837 |
133 | leukocyte degranulation (GO:0043299) | 2.72109213 |
134 | regulation of interleukin-4 production (GO:0032673) | 2.71983144 |
135 | alpha-beta T cell activation (GO:0046631) | 2.71550018 |
136 | negative regulation of type 2 immune response (GO:0002829) | 2.71352280 |
137 | tolerance induction (GO:0002507) | 2.71217422 |
138 | response to interferon-beta (GO:0035456) | 2.71193976 |
139 | sequestering of actin monomers (GO:0042989) | 2.70919577 |
140 | negative regulation of T cell apoptotic process (GO:0070233) | 2.70521699 |
141 | telomere maintenance via recombination (GO:0000722) | 2.69790426 |
142 | positive regulation of T cell mediated immunity (GO:0002711) | 2.69084883 |
143 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.69022354 |
144 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.68164668 |
145 | response to muramyl dipeptide (GO:0032495) | 2.64651417 |
146 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 2.64613724 |
147 | regulation of tolerance induction (GO:0002643) | 2.63009814 |
148 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.62142770 |
149 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.61521596 |
150 | regulation of alpha-beta T cell differentiation (GO:0046637) | 2.61190950 |
151 | positive regulation of tolerance induction (GO:0002645) | 2.59827127 |
152 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.59678001 |
153 | regulation of cell killing (GO:0031341) | 2.58018078 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.03011462 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.63329561 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.20164776 |
4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.92786843 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.66570175 |
6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.08181149 |
7 | MYC_22102868_ChIP-Seq_BL_Human | 3.04121847 |
8 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.79284908 |
9 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.77598789 |
10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.73262164 |
11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.72786341 |
12 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.72194154 |
13 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.65904002 |
14 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.62252365 |
15 | MYB_26560356_Chip-Seq_TH2_Human | 2.55370424 |
16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.45368203 |
17 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.44642227 |
18 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.39233964 |
19 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.38009541 |
20 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.32928528 |
21 | MAF_26560356_Chip-Seq_TH1_Human | 2.26525807 |
22 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.24747747 |
23 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.24506263 |
24 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.20811479 |
25 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.20560596 |
26 | MYB_26560356_Chip-Seq_TH1_Human | 2.17243684 |
27 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.16124051 |
28 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.14771405 |
29 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.13221041 |
30 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.11814985 |
31 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.11284244 |
32 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.09387445 |
33 | UTX_26944678_Chip-Seq_JUKART_Human | 2.05856429 |
34 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.05228968 |
35 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.93731435 |
36 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.89707957 |
37 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.89442209 |
38 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.85106595 |
39 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83569271 |
40 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.79433049 |
41 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.75080709 |
42 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.73241267 |
43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.72046169 |
44 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.70657398 |
45 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.70516313 |
46 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.68702149 |
47 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.68165402 |
48 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.66737015 |
49 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63345774 |
50 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.63238927 |
51 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.62772173 |
52 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.62040846 |
53 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.61108479 |
54 | MAF_26560356_Chip-Seq_TH2_Human | 1.56000644 |
55 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.54584884 |
56 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.54435104 |
57 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.54259471 |
58 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.52618175 |
59 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.52426855 |
60 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51347033 |
61 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.50316699 |
62 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.48475957 |
63 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.48063767 |
64 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.47621604 |
65 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.46714081 |
66 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.46075394 |
67 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.44229559 |
68 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.43677614 |
69 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.42696087 |
70 | GATA1_22025678_ChIP-Seq_K562_Human | 1.42577436 |
71 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.41081612 |
72 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.39630210 |
73 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.38570081 |
74 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38144244 |
75 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.34116006 |
76 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.33165462 |
77 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.30749151 |
78 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.28566966 |
79 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.26882336 |
80 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24231337 |
81 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.23834603 |
82 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.21315352 |
83 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.20745535 |
84 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.18039733 |
85 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.17690981 |
86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.17460768 |
87 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.16613071 |
88 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.15370787 |
89 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.13703166 |
90 | GATA1_19941826_ChIP-Seq_K562_Human | 1.13264588 |
91 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.13206733 |
92 | SPI1_23127762_ChIP-Seq_K562_Human | 1.11455406 |
93 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.10895588 |
94 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.09574163 |
95 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.08921982 |
96 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.08906748 |
97 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.04798746 |
98 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04450278 |
99 | GATA3_26560356_Chip-Seq_TH2_Human | 1.04397265 |
100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.03855090 |
101 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.03671080 |
102 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.03487644 |
103 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.02816757 |
104 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.02808088 |
105 | GATA3_26560356_Chip-Seq_TH1_Human | 1.02589516 |
106 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02284343 |
107 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01380188 |
108 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.00464243 |
109 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.00411100 |
110 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.99510570 |
111 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.95832880 |
112 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.95534198 |
113 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.95427889 |
114 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95182886 |
115 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94687694 |
116 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.93837621 |
117 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.93609875 |
118 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.93025688 |
119 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.92978282 |
120 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92226434 |
121 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.91841619 |
122 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.91478950 |
123 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.90466876 |
124 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.89916096 |
125 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.89330383 |
126 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88408449 |
127 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88268627 |
128 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.87695243 |
129 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.86435875 |
130 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.86294382 |
131 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85710803 |
132 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.85621643 |
133 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.85050394 |
134 | P300_27268052_Chip-Seq_Bcells_Human | 0.84307007 |
135 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.83542071 |
136 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.83516136 |
137 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.82540154 |
138 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.81335397 |
139 | GATA2_19941826_ChIP-Seq_K562_Human | 0.80084006 |
140 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77306894 |
141 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.76225802 |
142 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.76094182 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003763_abnormal_thymus_physiology | 4.44751499 |
2 | MP0001835_abnormal_antigen_presentation | 4.09993249 |
3 | MP0005671_abnormal_response_to | 4.03227258 |
4 | MP0002396_abnormal_hematopoietic_system | 3.76928896 |
5 | MP0000685_abnormal_immune_system | 3.45639316 |
6 | MP0002166_altered_tumor_susceptibility | 3.19066112 |
7 | MP0001800_abnormal_humoral_immune | 3.17415735 |
8 | MP0009785_altered_susceptibility_to | 3.01811201 |
9 | MP0002398_abnormal_bone_marrow | 2.90686146 |
10 | MP0002420_abnormal_adaptive_immunity | 2.78301430 |
11 | MP0001819_abnormal_immune_cell | 2.74467301 |
12 | MP0001790_abnormal_immune_system | 2.74072253 |
13 | MP0005387_immune_system_phenotype | 2.74072253 |
14 | MP0002723_abnormal_immune_serum | 2.73743779 |
15 | MP0005000_abnormal_immune_tolerance | 2.71690934 |
16 | MP0002006_tumorigenesis | 2.63624150 |
17 | MP0002452_abnormal_antigen_presenting | 2.63179715 |
18 | MP0005025_abnormal_response_to | 2.62077647 |
19 | MP0003880_abnormal_central_pattern | 2.61944443 |
20 | MP0000716_abnormal_immune_system | 2.47485112 |
21 | MP0009333_abnormal_splenocyte_physiolog | 2.37339117 |
22 | MP0000689_abnormal_spleen_morphology | 2.36249496 |
23 | MP0001873_stomach_inflammation | 2.35757619 |
24 | MP0002722_abnormal_immune_system | 2.35378555 |
25 | MP0000703_abnormal_thymus_morphology | 2.33507656 |
26 | MP0004859_abnormal_synaptic_plasticity | 2.32989945 |
27 | MP0002405_respiratory_system_inflammati | 2.25928039 |
28 | MP0002148_abnormal_hypersensitivity_rea | 2.14489078 |
29 | MP0001501_abnormal_sleep_pattern | 2.12452004 |
30 | MP0002429_abnormal_blood_cell | 2.12302228 |
31 | MP0003436_decreased_susceptibility_to | 2.11900686 |
32 | MP0008057_abnormal_DNA_replication | 2.10040178 |
33 | MP0004808_abnormal_hematopoietic_stem | 2.07302193 |
34 | MP0010155_abnormal_intestine_physiology | 2.00777660 |
35 | MP0002419_abnormal_innate_immunity | 2.00139307 |
36 | MP0003866_abnormal_defecation | 1.90067741 |
37 | MP0001853_heart_inflammation | 1.88608028 |
38 | MP0003724_increased_susceptibility_to | 1.88471258 |
39 | MP0005075_abnormal_melanosome_morpholog | 1.87601388 |
40 | MP0005464_abnormal_platelet_physiology | 1.86720675 |
41 | MP0010094_abnormal_chromosome_stability | 1.82559026 |
42 | MP0005174_abnormal_tail_pigmentation | 1.82252260 |
43 | MP0001968_abnormal_touch/_nociception | 1.77446606 |
44 | MP0004947_skin_inflammation | 1.72563313 |
45 | MP0000490_abnormal_crypts_of | 1.70213837 |
46 | MP0003693_abnormal_embryo_hatching | 1.68470914 |
47 | MP0000465_gastrointestinal_hemorrhage | 1.64649188 |
48 | MP0003635_abnormal_synaptic_transmissio | 1.64632267 |
49 | MP0005397_hematopoietic_system_phenotyp | 1.60078916 |
50 | MP0001545_abnormal_hematopoietic_system | 1.60078916 |
51 | MP0001845_abnormal_inflammatory_respons | 1.59330676 |
52 | MP0009745_abnormal_behavioral_response | 1.55899743 |
53 | MP0003077_abnormal_cell_cycle | 1.55370841 |
54 | MP0006082_CNS_inflammation | 1.51647671 |
55 | MP0002064_seizures | 1.48294776 |
56 | MP0002933_joint_inflammation | 1.45804896 |
57 | MP0002019_abnormal_tumor_incidence | 1.37782322 |
58 | MP0008007_abnormal_cellular_replicative | 1.37416086 |
59 | MP0008877_abnormal_DNA_methylation | 1.36662546 |
60 | MP0003300_gastrointestinal_ulcer | 1.36206194 |
61 | MP0000858_altered_metastatic_potential | 1.31235315 |
62 | MP0008058_abnormal_DNA_repair | 1.31054247 |
63 | MP0005646_abnormal_pituitary_gland | 1.27296291 |
64 | MP0003303_peritoneal_inflammation | 1.26576264 |
65 | MP0002272_abnormal_nervous_system | 1.25256290 |
66 | MP0002063_abnormal_learning/memory/cond | 1.24873115 |
67 | MP0008569_lethality_at_weaning | 1.23725944 |
68 | MP0003111_abnormal_nucleus_morphology | 1.21290538 |
69 | MP0008469_abnormal_protein_level | 1.20092816 |
70 | MP0002736_abnormal_nociception_after | 1.19383479 |
71 | MP0003787_abnormal_imprinting | 1.19063249 |
72 | MP0001486_abnormal_startle_reflex | 1.18050321 |
73 | MP0002095_abnormal_skin_pigmentation | 1.15209033 |
74 | MP0000604_amyloidosis | 1.13536146 |
75 | MP0003690_abnormal_glial_cell | 1.11943070 |
76 | MP0005310_abnormal_salivary_gland | 1.11335966 |
77 | MP0008872_abnormal_physiological_respon | 1.11024872 |
78 | MP0004957_abnormal_blastocyst_morpholog | 1.10886495 |
79 | MP0005423_abnormal_somatic_nervous | 1.10446625 |
80 | MP0002572_abnormal_emotion/affect_behav | 1.04747918 |
81 | MP0002009_preneoplasia | 1.02166056 |
82 | MP0004381_abnormal_hair_follicle | 0.99837537 |
83 | MP0009046_muscle_twitch | 0.96708579 |
84 | MP0002733_abnormal_thermal_nociception | 0.96659322 |
85 | MP0005645_abnormal_hypothalamus_physiol | 0.96558148 |
86 | MP0003329_amyloid_beta_deposits | 0.95010652 |
87 | MP0000015_abnormal_ear_pigmentation | 0.92701541 |
88 | MP0001970_abnormal_pain_threshold | 0.89917478 |
89 | MP0003045_fibrosis | 0.89240245 |
90 | MP0010352_gastrointestinal_tract_polyps | 0.88512799 |
91 | MP0005535_abnormal_body_temperature | 0.86044574 |
92 | MP0003075_altered_response_to | 0.85581286 |
93 | MP0001533_abnormal_skeleton_physiology | 0.82794732 |
94 | MP0004130_abnormal_muscle_cell | 0.81978237 |
95 | MP0003448_altered_tumor_morphology | 0.81428017 |
96 | MP0004510_myositis | 0.80843150 |
97 | MP0009278_abnormal_bone_marrow | 0.80727609 |
98 | MP0005166_decreased_susceptibility_to | 0.80366787 |
99 | MP0002735_abnormal_chemical_nociception | 0.79852135 |
100 | MP0008874_decreased_physiological_sensi | 0.79107125 |
101 | MP0003786_premature_aging | 0.78283894 |
102 | MP0000313_abnormal_cell_death | 0.77097494 |
103 | MP0002132_abnormal_respiratory_system | 0.74542996 |
104 | MP0001765_abnormal_ion_homeostasis | 0.72556748 |
105 | MP0006054_spinal_hemorrhage | 0.71100586 |
106 | MP0001905_abnormal_dopamine_level | 0.71002457 |
107 | MP0006276_abnormal_autonomic_nervous | 0.70975284 |
108 | MP0003633_abnormal_nervous_system | 0.70745403 |
109 | MP0001851_eye_inflammation | 0.69796579 |
110 | MP0002693_abnormal_pancreas_physiology | 0.66949720 |
111 | MP0002067_abnormal_sensory_capabilities | 0.65868913 |
112 | MP0003172_abnormal_lysosome_physiology | 0.65118655 |
113 | MP0002138_abnormal_hepatobiliary_system | 0.63105110 |
114 | MP0000477_abnormal_intestine_morphology | 0.63049457 |
115 | MP0001663_abnormal_digestive_system | 0.62912111 |
116 | MP0009763_increased_sensitivity_to | 0.62776938 |
117 | MP0000372_irregular_coat_pigmentation | 0.62567005 |
118 | MP0005409_darkened_coat_color | 0.60544250 |
119 | MP0002998_abnormal_bone_remodeling | 0.58917332 |
120 | MP0009764_decreased_sensitivity_to | 0.58073104 |
121 | MP0000350_abnormal_cell_proliferation | 0.57634781 |
122 | MP0000343_altered_response_to | 0.56988926 |
123 | MP0010307_abnormal_tumor_latency | 0.56586470 |
124 | MP0009765_abnormal_xenobiotic_induced | 0.56414206 |
125 | MP0001986_abnormal_taste_sensitivity | 0.51887321 |
126 | MP0001348_abnormal_lacrimal_gland | 0.50235704 |
127 | MP0003183_abnormal_peptide_metabolism | 0.49947497 |
128 | MP0000371_diluted_coat_color | 0.49920223 |
129 | MP0008873_increased_physiological_sensi | 0.46454142 |
130 | MP0001191_abnormal_skin_condition | 0.45918754 |
131 | MP0002136_abnormal_kidney_physiology | 0.44147287 |
132 | MP0003795_abnormal_bone_structure | 0.43283826 |
133 | MP0000609_abnormal_liver_physiology | 0.43122870 |
134 | MP0004147_increased_porphyrin_level | 0.42818687 |
135 | MP0005023_abnormal_wound_healing | 0.42650622 |
136 | MP0002083_premature_death | 0.40640664 |
137 | MP0002075_abnormal_coat/hair_pigmentati | 0.40586682 |
138 | MP0000598_abnormal_liver_morphology | 0.40374208 |
139 | MP0003943_abnormal_hepatobiliary_system | 0.40304672 |
140 | MP0009379_abnormal_foot_pigmentation | 0.39744130 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.35452197 |
2 | T lymphocytopenia (HP:0005403) | 5.17770746 |
3 | Abnormality of T cell number (HP:0011839) | 4.99568584 |
4 | Severe combined immunodeficiency (HP:0004430) | 4.95015940 |
5 | Recurrent bronchitis (HP:0002837) | 4.91174431 |
6 | IgM deficiency (HP:0002850) | 4.89211439 |
7 | Panhypogammaglobulinemia (HP:0003139) | 4.84747760 |
8 | Chronic otitis media (HP:0000389) | 4.57557092 |
9 | Abnormality of T cells (HP:0002843) | 4.50891609 |
10 | Combined immunodeficiency (HP:0005387) | 4.44524491 |
11 | IgG deficiency (HP:0004315) | 4.42179343 |
12 | Recurrent viral infections (HP:0004429) | 4.40173377 |
13 | Recurrent fungal infections (HP:0002841) | 4.26298988 |
14 | Recurrent cutaneous fungal infections (HP:0011370) | 4.26030325 |
15 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.26030325 |
16 | Thyroiditis (HP:0100646) | 4.24512132 |
17 | Abnormality of B cell number (HP:0010975) | 4.15287207 |
18 | B lymphocytopenia (HP:0010976) | 4.15287207 |
19 | Thrombocytosis (HP:0001894) | 4.02392183 |
20 | Hypoplasia of the thymus (HP:0000778) | 4.02083949 |
21 | Myositis (HP:0100614) | 4.00685836 |
22 | Agammaglobulinemia (HP:0004432) | 3.96248523 |
23 | Papilledema (HP:0001085) | 3.89380776 |
24 | Abnormality of T cell physiology (HP:0011840) | 3.72626648 |
25 | Focal motor seizures (HP:0011153) | 3.49316589 |
26 | Lymphopenia (HP:0001888) | 3.46167549 |
27 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.44741958 |
28 | Meningitis (HP:0001287) | 3.44084084 |
29 | Autoimmune hemolytic anemia (HP:0001890) | 3.41914179 |
30 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.36770655 |
31 | Abnormality of eosinophils (HP:0001879) | 3.36402392 |
32 | Stomatitis (HP:0010280) | 3.35643236 |
33 | Aplastic anemia (HP:0001915) | 3.32725541 |
34 | Stomach cancer (HP:0012126) | 3.31542733 |
35 | Abnormality of binocular vision (HP:0011514) | 3.28381219 |
36 | Diplopia (HP:0000651) | 3.28381219 |
37 | Chronic diarrhea (HP:0002028) | 3.23354990 |
38 | Recurrent abscess formation (HP:0002722) | 3.18902843 |
39 | Nasal polyposis (HP:0100582) | 3.18324907 |
40 | Abnormal number of erythroid precursors (HP:0012131) | 3.18233398 |
41 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.18068673 |
42 | Abnormality of the fingertips (HP:0001211) | 3.17078497 |
43 | Reticulocytopenia (HP:0001896) | 3.14258354 |
44 | Eosinophilia (HP:0001880) | 3.11580636 |
45 | Lymphoma (HP:0002665) | 3.09817175 |
46 | Febrile seizures (HP:0002373) | 3.08364399 |
47 | Eczematoid dermatitis (HP:0000976) | 3.08212536 |
48 | Recurrent skin infections (HP:0001581) | 3.02173188 |
49 | Granulocytopenia (HP:0001913) | 2.90659011 |
50 | Recurrent sinusitis (HP:0011108) | 2.85281328 |
51 | IgA deficiency (HP:0002720) | 2.83839367 |
52 | Leukocytosis (HP:0001974) | 2.80196482 |
53 | Bronchitis (HP:0012387) | 2.75842343 |
54 | Mediastinal lymphadenopathy (HP:0100721) | 2.74138456 |
55 | Vasculitis (HP:0002633) | 2.73763171 |
56 | Poikiloderma (HP:0001029) | 2.73523815 |
57 | Abnormality of the prostate (HP:0008775) | 2.71141694 |
58 | Recurrent bacterial skin infections (HP:0005406) | 2.71062672 |
59 | Abnormality of the nasal mucosa (HP:0000433) | 2.70177745 |
60 | Gastrointestinal stroma tumor (HP:0100723) | 2.67000284 |
61 | Inflammation of the large intestine (HP:0002037) | 2.62624141 |
62 | Pustule (HP:0200039) | 2.62397933 |
63 | Entropion (HP:0000621) | 2.58432017 |
64 | Gastrointestinal inflammation (HP:0004386) | 2.57802019 |
65 | Encephalitis (HP:0002383) | 2.57146790 |
66 | Focal seizures (HP:0007359) | 2.54196975 |
67 | Increased IgM level (HP:0003496) | 2.54046749 |
68 | Petechiae (HP:0000967) | 2.53932167 |
69 | Hemiplegia (HP:0002301) | 2.49345023 |
70 | Chronic sinusitis (HP:0011109) | 2.45573828 |
71 | Retrobulbar optic neuritis (HP:0100654) | 2.43396739 |
72 | Optic neuritis (HP:0100653) | 2.43396739 |
73 | Obstructive lung disease (HP:0006536) | 2.41320661 |
74 | Chronic obstructive pulmonary disease (HP:0006510) | 2.41320661 |
75 | Hemoptysis (HP:0002105) | 2.40552496 |
76 | Hypergammaglobulinemia (HP:0010702) | 2.39333014 |
77 | Cellulitis (HP:0100658) | 2.39053444 |
78 | Visual hallucinations (HP:0002367) | 2.39028204 |
79 | Chest pain (HP:0100749) | 2.38140959 |
80 | Myokymia (HP:0002411) | 2.36339242 |
81 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.36263326 |
82 | Prolonged bleeding time (HP:0003010) | 2.31764591 |
83 | Orchitis (HP:0100796) | 2.27071074 |
84 | Abnormality of DNA repair (HP:0003254) | 2.25367190 |
85 | Atonic seizures (HP:0010819) | 2.23623117 |
86 | Acute lymphatic leukemia (HP:0006721) | 2.23339616 |
87 | Autoimmune thrombocytopenia (HP:0001973) | 2.21106530 |
88 | Keratoconjunctivitis (HP:0001096) | 2.19023310 |
89 | Hypoproteinemia (HP:0003075) | 2.16395227 |
90 | Hypochromic anemia (HP:0001931) | 2.16349190 |
91 | Pulmonary embolism (HP:0002204) | 2.12268167 |
92 | Papilloma (HP:0012740) | 2.11329053 |
93 | Verrucae (HP:0200043) | 2.11329053 |
94 | Acute myeloid leukemia (HP:0004808) | 2.10255248 |
95 | Progressive cerebellar ataxia (HP:0002073) | 2.08165478 |
96 | Basal cell carcinoma (HP:0002671) | 2.07338486 |
97 | Pulmonary infiltrates (HP:0002113) | 2.06794974 |
98 | Pallor (HP:0000980) | 2.06596383 |
99 | Epistaxis (HP:0000421) | 2.05405101 |
100 | Epileptic encephalopathy (HP:0200134) | 2.03700967 |
101 | Skin rash (HP:0000988) | 2.02628712 |
102 | Increased IgE level (HP:0003212) | 1.99577804 |
103 | Prostate neoplasm (HP:0100787) | 1.99076751 |
104 | Keratoconjunctivitis sicca (HP:0001097) | 1.98601141 |
105 | Joint swelling (HP:0001386) | 1.98558317 |
106 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.97313131 |
107 | Colitis (HP:0002583) | 1.97139512 |
108 | Amaurosis fugax (HP:0100576) | 1.95886269 |
109 | Recurrent otitis media (HP:0000403) | 1.93044450 |
110 | Arterial thrombosis (HP:0004420) | 1.92373085 |
111 | Pancytopenia (HP:0001876) | 1.91031708 |
112 | Episodic fever (HP:0001954) | 1.90706373 |
113 | Cheilitis (HP:0100825) | 1.90519826 |
114 | 11 pairs of ribs (HP:0000878) | 1.90411039 |
115 | Postural instability (HP:0002172) | 1.88736347 |
116 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.87204724 |
117 | Abnormality of macrophages (HP:0004311) | 1.85569782 |
118 | Alveolar cell carcinoma (HP:0006519) | 1.85477287 |
119 | Neutropenia (HP:0001875) | 1.84547065 |
120 | Pulmonary fibrosis (HP:0002206) | 1.83912298 |
121 | Vertigo (HP:0002321) | 1.83828406 |
122 | Sepsis (HP:0100806) | 1.83816826 |
123 | Gastrointestinal infarctions (HP:0005244) | 1.82982212 |
124 | Spontaneous hematomas (HP:0007420) | 1.82250091 |
125 | Skin ulcer (HP:0200042) | 1.81391110 |
126 | Supranuclear gaze palsy (HP:0000605) | 1.76772176 |
127 | Slow saccadic eye movements (HP:0000514) | 1.76610688 |
128 | Acute hepatic failure (HP:0006554) | 1.75347094 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 5.34763775 |
2 | TXK | 4.36155789 |
3 | RIPK4 | 3.86973964 |
4 | KIT | 3.77763276 |
5 | ZAP70 | 2.67068819 |
6 | JAK3 | 2.64200749 |
7 | TEC | 2.56479335 |
8 | IKBKE | 2.39137626 |
9 | FLT3 | 2.38517910 |
10 | BTK | 2.33478850 |
11 | ITK | 2.33345227 |
12 | TYK2 | 2.31086964 |
13 | FGFR4 | 2.29712201 |
14 | DAPK2 | 2.28141895 |
15 | TBK1 | 1.95092478 |
16 | CAMKK1 | 1.91288099 |
17 | GRK5 | 1.87908383 |
18 | CSF1R | 1.86932540 |
19 | SYK | 1.85863691 |
20 | BMPR2 | 1.85642806 |
21 | EEF2K | 1.75555268 |
22 | MAP3K12 | 1.66935136 |
23 | LCK | 1.66742493 |
24 | EPHA4 | 1.65631937 |
25 | GRK6 | 1.60826375 |
26 | TESK2 | 1.60210184 |
27 | STK10 | 1.56930137 |
28 | NLK | 1.53437732 |
29 | KDR | 1.46018351 |
30 | NUAK1 | 1.45596800 |
31 | IRAK4 | 1.43194414 |
32 | FGFR3 | 1.42834381 |
33 | NME2 | 1.40280754 |
34 | PRPF4B | 1.39604207 |
35 | PIM2 | 1.39529631 |
36 | FRK | 1.37350749 |
37 | CAMKK2 | 1.27012669 |
38 | JAK1 | 1.26582552 |
39 | TNIK | 1.24414495 |
40 | CDC7 | 1.23233608 |
41 | BLK | 1.21889916 |
42 | LRRK2 | 1.20626472 |
43 | MAP2K2 | 1.19911241 |
44 | MAP3K14 | 1.19417533 |
45 | LYN | 1.18102284 |
46 | PAK6 | 1.16160420 |
47 | WEE1 | 1.10126444 |
48 | FES | 1.09944878 |
49 | CLK1 | 1.09461456 |
50 | HCK | 1.08650026 |
51 | TAOK3 | 1.07534101 |
52 | PIM1 | 1.06053192 |
53 | TLK1 | 1.05860098 |
54 | STK16 | 1.05669511 |
55 | IKBKB | 0.98218980 |
56 | VRK1 | 0.97938092 |
57 | RPS6KB2 | 0.95399775 |
58 | MAP3K10 | 0.94874776 |
59 | PINK1 | 0.89277988 |
60 | CSK | 0.89149055 |
61 | PASK | 0.88804700 |
62 | MAP2K3 | 0.88630380 |
63 | TGFBR1 | 0.88043062 |
64 | NTRK3 | 0.86999832 |
65 | BRSK2 | 0.86158084 |
66 | PDK1 | 0.83488770 |
67 | SCYL2 | 0.82894586 |
68 | ACVR1B | 0.82097537 |
69 | MAPK13 | 0.78961739 |
70 | EIF2AK3 | 0.78614965 |
71 | ATR | 0.77518719 |
72 | UHMK1 | 0.77374608 |
73 | SIK3 | 0.76804663 |
74 | SRPK1 | 0.75572510 |
75 | MAPK11 | 0.74302944 |
76 | MAPK12 | 0.74102013 |
77 | TNK2 | 0.73187717 |
78 | RPS6KA4 | 0.72145178 |
79 | SIK2 | 0.72104259 |
80 | CDK4 | 0.71823260 |
81 | MST4 | 0.71658042 |
82 | MAP3K1 | 0.71112180 |
83 | EIF2AK1 | 0.69640326 |
84 | PKN2 | 0.69547937 |
85 | MAP3K13 | 0.66181718 |
86 | MAP4K2 | 0.65750986 |
87 | CAMK1 | 0.64170201 |
88 | MAPKAPK3 | 0.63247471 |
89 | PRKCQ | 0.62083350 |
90 | INSRR | 0.60905726 |
91 | TSSK6 | 0.60696558 |
92 | NTRK2 | 0.55323146 |
93 | STK4 | 0.53138946 |
94 | DAPK1 | 0.52658405 |
95 | TGFBR2 | 0.52047065 |
96 | JAK2 | 0.51829625 |
97 | MAP3K7 | 0.51174170 |
98 | BUB1 | 0.50289707 |
99 | FYN | 0.49694281 |
100 | MAP3K11 | 0.49005145 |
101 | MARK3 | 0.48989603 |
102 | ILK | 0.48772742 |
103 | STK11 | 0.48276717 |
104 | CHUK | 0.48190173 |
105 | NEK2 | 0.48142750 |
106 | CDK7 | 0.47447585 |
107 | ADRBK2 | 0.46464392 |
108 | MAPK4 | 0.46424108 |
109 | ERN1 | 0.46175331 |
110 | RPS6KA5 | 0.45224397 |
111 | CCNB1 | 0.42053555 |
112 | CDK8 | 0.40841329 |
113 | MAPK7 | 0.40379120 |
114 | RAF1 | 0.39692132 |
115 | DYRK3 | 0.39252302 |
116 | NEK6 | 0.38090092 |
117 | HIPK2 | 0.37962230 |
118 | CAMK4 | 0.36756819 |
119 | RPS6KA6 | 0.36712288 |
120 | BRD4 | 0.36267374 |
121 | PRKCH | 0.35440715 |
122 | TAOK1 | 0.35241901 |
123 | AURKB | 0.35191555 |
124 | PIK3CG | 0.34752659 |
125 | CDK19 | 0.34388042 |
126 | SGK2 | 0.33356961 |
127 | ALK | 0.31945022 |
128 | MYLK | 0.29092326 |
129 | DYRK1A | 0.28942189 |
130 | BRSK1 | 0.28786508 |
131 | MARK2 | 0.28675170 |
132 | GRK7 | 0.28647327 |
133 | CDK5 | 0.28174618 |
134 | BCKDK | 0.28167985 |
135 | MINK1 | 0.28047966 |
136 | MAPK3 | 0.27243152 |
137 | OXSR1 | 0.26811498 |
138 | IRAK2 | 0.25126266 |
139 | PTK2B | 0.24964137 |
140 | STK38 | 0.24711271 |
141 | MAP2K6 | 0.24665347 |
142 | MAP2K1 | 0.23735336 |
143 | PRKCB | 0.23467733 |
144 | PRKCD | 0.22199131 |
145 | MATK | 0.21855927 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.26687619 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.41496858 |
3 | Ribosome_Homo sapiens_hsa03010 | 2.96092930 |
4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.73162982 |
5 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.59088636 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 2.46146587 |
7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.45246532 |
8 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.43950693 |
9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.42998992 |
10 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.37642564 |
11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.36803748 |
12 | Measles_Homo sapiens_hsa05162 | 2.34963517 |
13 | Allograft rejection_Homo sapiens_hsa05330 | 2.21767464 |
14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.17950802 |
15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.17436085 |
16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.16267907 |
17 | Base excision repair_Homo sapiens_hsa03410 | 2.16102382 |
18 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.91006514 |
19 | Homologous recombination_Homo sapiens_hsa03440 | 1.81588627 |
20 | Spliceosome_Homo sapiens_hsa03040 | 1.81024508 |
21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.79914571 |
22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.73853588 |
23 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.69287276 |
24 | Long-term potentiation_Homo sapiens_hsa04720 | 1.69262109 |
25 | Nicotine addiction_Homo sapiens_hsa05033 | 1.66690527 |
26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.65749579 |
27 | Morphine addiction_Homo sapiens_hsa05032 | 1.59817867 |
28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.45554543 |
29 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.38031152 |
30 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.37958014 |
31 | Circadian entrainment_Homo sapiens_hsa04713 | 1.36052552 |
32 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.35003082 |
33 | Asthma_Homo sapiens_hsa05310 | 1.28909784 |
34 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.27696790 |
35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26738277 |
36 | Salivary secretion_Homo sapiens_hsa04970 | 1.25858884 |
37 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.25008522 |
38 | Proteasome_Homo sapiens_hsa03050 | 1.21197551 |
39 | RNA degradation_Homo sapiens_hsa03018 | 1.20617152 |
40 | Renin secretion_Homo sapiens_hsa04924 | 1.17505768 |
41 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.16610997 |
42 | Olfactory transduction_Homo sapiens_hsa04740 | 1.16126031 |
43 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.15100144 |
44 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.14387601 |
45 | Viral myocarditis_Homo sapiens_hsa05416 | 1.13186453 |
46 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.12427620 |
47 | Hepatitis B_Homo sapiens_hsa05161 | 1.09534890 |
48 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.08550239 |
49 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.06917533 |
50 | RNA polymerase_Homo sapiens_hsa03020 | 1.06579231 |
51 | Cell cycle_Homo sapiens_hsa04110 | 1.04793231 |
52 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.02775508 |
53 | Influenza A_Homo sapiens_hsa05164 | 1.02008542 |
54 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.01913082 |
55 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.01805205 |
56 | GABAergic synapse_Homo sapiens_hsa04727 | 1.00672383 |
57 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.98765256 |
58 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.98670182 |
59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.98353285 |
60 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.97844252 |
61 | Shigellosis_Homo sapiens_hsa05131 | 0.96945948 |
62 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.96922595 |
63 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.96215139 |
64 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.94406509 |
65 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.93837533 |
66 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.93772499 |
67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.92739602 |
68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90826137 |
69 | Legionellosis_Homo sapiens_hsa05134 | 0.90740632 |
70 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.89494362 |
71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.88088022 |
72 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.87365908 |
73 | Insulin secretion_Homo sapiens_hsa04911 | 0.87130281 |
74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.85909132 |
75 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.83553511 |
76 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.83483711 |
77 | RNA transport_Homo sapiens_hsa03013 | 0.83267703 |
78 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.82918060 |
79 | Taste transduction_Homo sapiens_hsa04742 | 0.82726212 |
80 | Apoptosis_Homo sapiens_hsa04210 | 0.81328032 |
81 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.80921697 |
82 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.80755464 |
83 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.79223982 |
84 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.78414203 |
85 | Phototransduction_Homo sapiens_hsa04744 | 0.73686800 |
86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.73624912 |
87 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.73502496 |
88 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.72003096 |
89 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.71533147 |
90 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71382692 |
91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.71381012 |
92 | Long-term depression_Homo sapiens_hsa04730 | 0.70645317 |
93 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.69691022 |
94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.68122436 |
95 | Malaria_Homo sapiens_hsa05144 | 0.67176425 |
96 | Protein export_Homo sapiens_hsa03060 | 0.66609167 |
97 | Platelet activation_Homo sapiens_hsa04611 | 0.65956102 |
98 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.65079419 |
99 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.64511849 |
100 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.64503830 |
101 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.64323175 |
102 | Pertussis_Homo sapiens_hsa05133 | 0.63396421 |
103 | Tuberculosis_Homo sapiens_hsa05152 | 0.62510917 |
104 | Thyroid cancer_Homo sapiens_hsa05216 | 0.61515768 |
105 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.60238684 |
106 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.58996450 |
107 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.56977362 |
108 | Basal transcription factors_Homo sapiens_hsa03022 | 0.56504133 |
109 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.56480110 |
110 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55725768 |
111 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.53794456 |
112 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.53035991 |
113 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51871679 |
114 | Hepatitis C_Homo sapiens_hsa05160 | 0.51646580 |
115 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50131891 |
116 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.49886311 |
117 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.49550021 |
118 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.48855006 |
119 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.48639119 |
120 | Purine metabolism_Homo sapiens_hsa00230 | 0.48612152 |
121 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.48341121 |
122 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.47379546 |
123 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46660991 |
124 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.46451020 |
125 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45753146 |
126 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45728151 |
127 | Colorectal cancer_Homo sapiens_hsa05210 | 0.45196747 |
128 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44882203 |
129 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.44468309 |
130 | Other glycan degradation_Homo sapiens_hsa00511 | 0.43608082 |
131 | Endocytosis_Homo sapiens_hsa04144 | 0.43453879 |
132 | Glioma_Homo sapiens_hsa05214 | 0.42928742 |
133 | Salmonella infection_Homo sapiens_hsa05132 | 0.41876715 |
134 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.41707819 |
135 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.41008284 |
136 | Sulfur relay system_Homo sapiens_hsa04122 | 0.40822236 |
137 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40460851 |
138 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.39700199 |
139 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.37671063 |
140 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.35724505 |
141 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.34997129 |
142 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.33630153 |
143 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.29681177 |
144 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.28746496 |
145 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.27673919 |
146 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.25743834 |
147 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25506655 |
148 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24494305 |
149 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.24382183 |
150 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.21717932 |
151 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.19471279 |