TEX29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.59962257
2motile cilium assembly (GO:0044458)9.42697009
3spermatid development (GO:0007286)9.29319643
4regulation of cilium movement (GO:0003352)8.71995712
5cilium movement (GO:0003341)8.54215665
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.98791526
7single fertilization (GO:0007338)7.70338492
8sperm capacitation (GO:0048240)7.26023085
9piRNA metabolic process (GO:0034587)7.13371891
10male meiosis (GO:0007140)6.99743802
11synaptonemal complex organization (GO:0070193)6.68717774
12microtubule depolymerization (GO:0007019)6.54403319
13synaptonemal complex assembly (GO:0007130)6.47808623
14fertilization (GO:0009566)6.36627303
15spermatogenesis (GO:0007283)6.33697654
16male gamete generation (GO:0048232)6.31119725
17negative regulation of inclusion body assembly (GO:0090084)6.30377530
18organic cation transport (GO:0015695)6.07297041
19gamete generation (GO:0007276)5.89002704
20calcium ion-dependent exocytosis (GO:0017156)5.66948353
21ventricular system development (GO:0021591)5.57052544
22protein targeting to Golgi (GO:0000042)5.55749433
23cellular process involved in reproduction in multicellular organism (GO:0022412)5.29370092
24retrograde transport, vesicle recycling within Golgi (GO:0000301)5.24256793
25establishment of protein localization to Golgi (GO:0072600)5.20416104
26germ cell development (GO:0007281)5.20046036
27cell recognition (GO:0008037)5.18971658
28regulation of inclusion body assembly (GO:0090083)5.14685146
29glutamate secretion (GO:0014047)5.10362983
30regulation of microtubule-based movement (GO:0060632)5.00442703
31multicellular organismal reproductive process (GO:0048609)4.65038249
32male meiosis I (GO:0007141)4.61070029
33positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.60848704
34microtubule severing (GO:0051013)4.60261807
35left/right pattern formation (GO:0060972)4.56015093
36regulation of synaptic vesicle exocytosis (GO:2000300)4.54812453
37DNA methylation involved in gamete generation (GO:0043046)4.47581043
38synaptic vesicle exocytosis (GO:0016079)4.39464177
39spermatid nucleus differentiation (GO:0007289)4.39130080
40chromosome organization involved in meiosis (GO:0070192)4.36801881
41glycerol ether metabolic process (GO:0006662)4.32975549
42protein localization to synapse (GO:0035418)4.29676503
43regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.27037366
44seminiferous tubule development (GO:0072520)4.24358491
45regulation of synaptic vesicle transport (GO:1902803)4.12652332
46protein localization to Golgi apparatus (GO:0034067)4.11031004
47meiotic nuclear division (GO:0007126)4.02366517
48ether metabolic process (GO:0018904)3.99212668
49dendritic spine morphogenesis (GO:0060997)3.97652107
50synaptic vesicle docking involved in exocytosis (GO:0016081)3.94428170
51response to pheromone (GO:0019236)3.93607669
52urinary tract smooth muscle contraction (GO:0014848)3.89569370
53protein polyglutamylation (GO:0018095)3.87824676
54chromosome condensation (GO:0030261)3.85658649
55neuronal ion channel clustering (GO:0045161)3.84933446
56DNA packaging (GO:0006323)3.77463725
57protein localization to cilium (GO:0061512)3.76686323
58regulation of short-term neuronal synaptic plasticity (GO:0048172)3.76037648
59neurofilament cytoskeleton organization (GO:0060052)3.75699069
60multicellular organismal development (GO:0007275)3.74558840
61regulation of glutamate receptor signaling pathway (GO:1900449)3.69505951
62response to acidic pH (GO:0010447)3.68267579
63positive regulation of dendritic spine development (GO:0060999)3.66669002
64cellular potassium ion homeostasis (GO:0030007)3.61395272
65dendritic spine organization (GO:0097061)3.58355389
66monoubiquitinated protein deubiquitination (GO:0035520)3.58288460
67intraciliary transport (GO:0042073)3.57756404
68genitalia morphogenesis (GO:0035112)3.57121412
69meiosis I (GO:0007127)3.56984423
70membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.56194420
71chaperone-mediated protein complex assembly (GO:0051131)3.55124608
72synaptic vesicle maturation (GO:0016188)3.53780618
73cilium organization (GO:0044782)3.45528731
74regulation of glycogen (starch) synthase activity (GO:2000465)3.45403184
75microtubule polymerization or depolymerization (GO:0031109)3.42797937
76cilium assembly (GO:0042384)3.38423493
77cell-cell junction maintenance (GO:0045217)3.35025356
78positive regulation of membrane potential (GO:0045838)3.34800772
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.34606993
80regulation of response to food (GO:0032095)3.30336640
81sodium ion export (GO:0071436)3.28497756
82sequestering of actin monomers (GO:0042989)3.26776657
83single strand break repair (GO:0000012)3.26668835
84meiotic cell cycle (GO:0051321)3.23656068
85detection of calcium ion (GO:0005513)3.21308688
86cilium morphogenesis (GO:0060271)3.21185750
87regulation of excitatory postsynaptic membrane potential (GO:0060079)3.20742670
88regulation of sensory perception (GO:0051931)3.16400463
89regulation of sensory perception of pain (GO:0051930)3.16400463
90protein K11-linked deubiquitination (GO:0035871)3.13915043
91regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00433.11831281
92microtubule-based movement (GO:0007018)3.11552345
93synaptic transmission, glutamatergic (GO:0035249)3.10353351
94cellular component assembly involved in morphogenesis (GO:0010927)3.09116582
95neuromuscular process controlling balance (GO:0050885)3.07105174
96nucleoside diphosphate phosphorylation (GO:0006165)3.05598756
97protein refolding (GO:0042026)3.05534641
98polyol catabolic process (GO:0046174)3.05384322
99locomotory exploration behavior (GO:0035641)3.05353045
100regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.04165005
101regulation of spindle checkpoint (GO:0090231)3.02504224
102positive regulation of Rab GTPase activity (GO:0032851)2.99743758
103regulation of Rab GTPase activity (GO:0032313)2.99743758
104lactate metabolic process (GO:0006089)2.97960642
105sexual reproduction (GO:0019953)2.97604314
106detection of light stimulus involved in sensory perception (GO:0050962)2.95831896
107detection of light stimulus involved in visual perception (GO:0050908)2.95831896
108axoneme assembly (GO:0035082)2.95140097
109membrane depolarization during action potential (GO:0086010)2.93103484
110centriole assembly (GO:0098534)2.92204958
111negative regulation of organelle assembly (GO:1902116)2.91466652
112alditol metabolic process (GO:0019400)2.90684127
113regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.88871468
114left/right axis specification (GO:0070986)2.87115876
115cerebral cortex neuron differentiation (GO:0021895)2.85329921
116neurotransmitter secretion (GO:0007269)2.85247417
117regulation of transcription involved in cell fate commitment (GO:0060850)2.84655764
118regulation of postsynaptic membrane potential (GO:0060078)2.84588271
119amino-acid betaine transport (GO:0015838)2.84199178
120carnitine transport (GO:0015879)2.84199178
121ionotropic glutamate receptor signaling pathway (GO:0035235)2.83008530
122nucleus organization (GO:0006997)2.82924422
123mitotic sister chromatid cohesion (GO:0007064)2.82843122
124coenzyme catabolic process (GO:0009109)2.80983537
125peptidyl-glutamic acid modification (GO:0018200)2.80228742
126vocalization behavior (GO:0071625)2.80160701
127regulation of neurotransmitter secretion (GO:0046928)2.79152248
128chemosensory behavior (GO:0007635)2.76405714
129negative regulation of dendrite morphogenesis (GO:0050774)2.76018206
130positive regulation of synapse maturation (GO:0090129)2.75905517
131glycolytic process (GO:0006096)2.75601874
132cellular response to nerve growth factor stimulus (GO:1990090)2.75099752
133response to nerve growth factor (GO:1990089)2.75099752
134presynaptic membrane organization (GO:0097090)2.74560046
135regulation of cilium assembly (GO:1902017)2.72250227
136regulation of chromatin binding (GO:0035561)2.70391699
137positive regulation of neurotransmitter secretion (GO:0001956)2.69225042
138L-amino acid import (GO:0043092)2.68214231
139carnitine transmembrane transport (GO:1902603)2.67451736
140positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.66665992
141centriole replication (GO:0007099)2.64902148
142regulation of p38MAPK cascade (GO:1900744)2.63727609
143detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.63604806
144detection of temperature stimulus involved in sensory perception (GO:0050961)2.63604806
145gene silencing by RNA (GO:0031047)2.62111883
146regulation of ARF protein signal transduction (GO:0032012)2.62072232
147membrane depolarization (GO:0051899)2.60661735
148positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.60256309
149synapsis (GO:0007129)2.58965706
150neuron-neuron synaptic transmission (GO:0007270)2.58305903
151negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.55981673
152regulation of neuronal synaptic plasticity (GO:0048168)2.55800432
153negative regulation of response to food (GO:0032096)2.54811689
154negative regulation of appetite (GO:0032099)2.54811689
155phosphatidylethanolamine biosynthetic process (GO:0006646)2.54676516
156activation of protein kinase B activity (GO:0032148)2.54236869
157meiotic cell cycle process (GO:1903046)2.53564166
158RNA destabilization (GO:0050779)2.53171047
159glycerol metabolic process (GO:0006071)2.51594504
160regulation of centriole replication (GO:0046599)2.51029692
161fusion of sperm to egg plasma membrane (GO:0007342)13.7734708
162sperm motility (GO:0030317)13.2497689
163cell wall macromolecule catabolic process (GO:0016998)12.8271122
164cell wall macromolecule metabolic process (GO:0044036)12.8271122
165acrosome reaction (GO:0007340)11.8369721
166multicellular organism reproduction (GO:0032504)11.4920738
167sperm-egg recognition (GO:0035036)11.4603091
168cilium or flagellum-dependent cell motility (GO:0001539)10.9107779
169acrosome assembly (GO:0001675)10.8724024
170plasma membrane fusion (GO:0045026)10.5219262
171epithelial cilium movement (GO:0003351)10.3566975
172binding of sperm to zona pellucida (GO:0007339)10.3140243
173cell-cell recognition (GO:0009988)10.2451774
174axonemal dynein complex assembly (GO:0070286)10.1211161

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.76964511
2EZH2_22144423_ChIP-Seq_EOC_Human5.05278974
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.27119961
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.15741040
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.04838502
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.03415305
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.98148192
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.60391914
9SUZ12_27294783_Chip-Seq_ESCs_Mouse2.38617036
10DROSHA_22980978_ChIP-Seq_HELA_Human2.36987779
11THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.35593581
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.27733424
13EZH2_27294783_Chip-Seq_ESCs_Mouse2.26776992
14IKZF1_21737484_ChIP-ChIP_HCT116_Human2.22560165
15NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.21656622
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.20110767
17JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19248954
18VDR_22108803_ChIP-Seq_LS180_Human2.17312602
19JARID2_20064375_ChIP-Seq_MESCs_Mouse2.15666667
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.13250845
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12553713
22EZH2_27304074_Chip-Seq_ESCs_Mouse2.08769242
23SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.08315575
24SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.06909098
25GATA1_26923725_Chip-Seq_HPCs_Mouse2.02360006
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.98966267
27EZH2_18974828_ChIP-Seq_MESCs_Mouse1.98966267
28FLI1_27457419_Chip-Seq_LIVER_Mouse1.94582853
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.94021558
30CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.93124387
31SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.89898433
32ZNF274_21170338_ChIP-Seq_K562_Hela1.89635695
33EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.87017885
34RARB_27405468_Chip-Seq_BRAIN_Mouse1.84499961
35EED_16625203_ChIP-ChIP_MESCs_Mouse1.83656927
36LXR_22292898_ChIP-Seq_THP-1_Human1.81940533
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.78295766
38REST_18959480_ChIP-ChIP_MESCs_Mouse1.76159811
39KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.73553829
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.71165737
41MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.70632137
42STAT1_17558387_ChIP-Seq_HELA_Human1.70293219
43PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68447284
44CTCF_27219007_Chip-Seq_Bcells_Human1.66981356
45TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.66171906
46WDR5_24793694_ChIP-Seq_LNCAP_Human1.66098757
47CBX2_27304074_Chip-Seq_ESCs_Mouse1.63415939
48ELK4_26923725_Chip-Seq_MESODERM_Mouse1.63209087
49ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59074452
50SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.57028516
51GBX2_23144817_ChIP-Seq_PC3_Human1.53961534
52TAL1_26923725_Chip-Seq_HPCs_Mouse1.52348426
53KDM2B_26808549_Chip-Seq_REH_Human1.51964110
54SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.51560505
55RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.48958027
56SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.45732903
57CBP_20019798_ChIP-Seq_JUKART_Human1.45157952
58IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45157952
59SOX2_22085726_ChIP-Seq_NPCs_Mouse1.42781876
60GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.42158776
61FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41971802
62EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.39694667
63KAP1_22055183_ChIP-Seq_ESCs_Mouse1.38262266
64REST_21632747_ChIP-Seq_MESCs_Mouse1.38198198
65KDM2B_26808549_Chip-Seq_K562_Human1.37874468
66GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.37427235
67PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.35123005
68DNAJC2_21179169_ChIP-ChIP_NT2_Human1.34714418
69TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34468225
70GATA3_21867929_ChIP-Seq_CD8_Mouse1.30469046
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.28307243
72TAF15_26573619_Chip-Seq_HEK293_Human1.28024557
73ERG_21242973_ChIP-ChIP_JURKAT_Human1.27884118
74KDM2B_26808549_Chip-Seq_SUP-B15_Human1.27177507
75TET1_21490601_ChIP-Seq_MESCs_Mouse1.26306065
76ZFP57_27257070_Chip-Seq_ESCs_Mouse1.26093409
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25760139
78GATA3_21867929_ChIP-Seq_TH1_Mouse1.24438612
79PCGF2_27294783_Chip-Seq_NPCs_Mouse1.24338208
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.23168924
81FLI1_21867929_ChIP-Seq_TH2_Mouse1.22290225
82LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.21550560
83CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21457416
84SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.21143526
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.20868857
86SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.19972239
87RUNX1_26923725_Chip-Seq_HPCs_Mouse1.19663126
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19649458
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19649458
90SMC4_20622854_ChIP-Seq_HELA_Human1.19335175
91RNF2_27304074_Chip-Seq_NSC_Mouse1.17643774
92FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.16850443
93GF1_26923725_Chip-Seq_HPCs_Mouse1.15858993
94CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15424980
95PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14749991
96SUZ12_27294783_Chip-Seq_NPCs_Mouse1.14389640
97P53_21459846_ChIP-Seq_SAOS-2_Human1.14079235
98NANOG_18555785_Chip-Seq_ESCs_Mouse1.12733917
99P68_20966046_ChIP-Seq_HELA_Human1.12711052
100RING1B_27294783_Chip-Seq_ESCs_Mouse1.11183476
101OCT4_19829295_ChIP-Seq_ESCs_Human1.11039968
102MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10417816
103EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09676634
104MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09553746
105KLF4_19829295_ChIP-Seq_ESCs_Human1.09247672
106EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09018063
107CRX_20693478_ChIP-Seq_RETINA_Mouse1.07540182
108CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07500548
109P53_22387025_ChIP-Seq_ESCs_Mouse1.07050493
110SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06613338
111CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06437710
112RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.06350271
113TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03765707
114ERG_20517297_ChIP-Seq_VCAP_Human1.03737380
115NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02624529
116RAD21_21589869_ChIP-Seq_MESCs_Mouse1.02103590
117OCT4_18555785_Chip-Seq_ESCs_Mouse1.01922068
118PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.01815425
119ERA_21632823_ChIP-Seq_H3396_Human1.01742890
120CMYC_18555785_Chip-Seq_ESCs_Mouse1.01318371
121P300_18555785_Chip-Seq_ESCs_Mouse1.01148180
122PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.00847157
123RAC3_21632823_ChIP-Seq_H3396_Human1.00665533
124EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00067795
125P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99950881
126SPI1_26923725_Chip-Seq_HPCs_Mouse0.99900112
127RARG_19884340_ChIP-ChIP_MEFs_Mouse0.98955557
128VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98909668
129EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.98565834
130SOX9_26525672_Chip-Seq_HEART_Mouse0.98063503
131TDRD3_21172665_ChIP-Seq_MCF-7_Human0.97926795
132PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97834755
133SMAD4_21741376_ChIP-Seq_EPCs_Human0.97501440
134PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.96970140
135EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96565513
136RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.96396564
137BCL6_27268052_Chip-Seq_Bcells_Human0.96260991
138STAT3_18555785_ChIP-Seq_MESCs_Mouse0.96146861
139MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.96089791
140KLF4_18555785_Chip-Seq_ESCs_Mouse0.94871176
141SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.94528522
142MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.94526930
143ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94396118
144TP53_18474530_ChIP-ChIP_U2OS_Human0.94309201
145SA1_27219007_Chip-Seq_Bcells_Human0.94116547
146TP53_20018659_ChIP-ChIP_R1E_Mouse0.93922126
147SA1_27219007_Chip-Seq_ERYTHROID_Human0.93419730
148MYC_27129775_Chip-Seq_CORNEA_Mouse0.93107797
149NFYB_21822215_ChIP-Seq_K562_Human0.92831730
150RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.92605630
151OCT4_21477851_ChIP-Seq_ESCs_Mouse0.92556396
152ESRRB_18555785_Chip-Seq_ESCs_Mouse0.92199920
153SUZ12_18555785_Chip-Seq_ESCs_Mouse0.91944727
154EZH2_27294783_Chip-Seq_NPCs_Mouse0.91788504
155OCT1_27270436_Chip-Seq_PROSTATE_Human0.91395409
156CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.91127910
157GATA1_19941827_ChIP-Seq_MEL86_Mouse0.90699874
158SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.90626488
159CTCF_20526341_ChIP-Seq_ESCs_Human0.90372494
160SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.89573387
161TET1_21451524_ChIP-Seq_MESCs_Mouse0.89487589
162TBL1_22424771_ChIP-Seq_293T_Human0.89222518
163SMAD3_21741376_ChIP-Seq_ESCs_Human0.89184473
164SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88901539
165ETV1_20927104_ChIP-Seq_GIST48_Human0.88777971
166KDM2B_26808549_Chip-Seq_JURKAT_Human0.88357633
167CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.88346264
168OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.88174225
169PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.87822607
170KDM2B_26808549_Chip-Seq_DND41_Human0.87718294
171SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87688554
172TAF2_19829295_ChIP-Seq_ESCs_Human0.87252481
173PU1_27457419_Chip-Seq_LIVER_Mouse0.86593904
174UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86521632
175ETV2_25802403_ChIP-Seq_MESCs_Mouse0.86408505
176SOX11_22085726_ChIP-Seq_ESNs_Mouse0.86207023
177GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86183307
178SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85882638
179ZFP281_27345836_Chip-Seq_ESCs_Mouse0.84932192
180TP63_22573176_ChIP-Seq_HFKS_Human0.84829398

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.89903041
2MP0001929_abnormal_gametogenesis5.30789637
3MP0004859_abnormal_synaptic_plasticity4.22680846
4MP0008877_abnormal_DNA_methylation4.03479156
5MP0005503_abnormal_tendon_morphology3.74897953
6MP0005423_abnormal_somatic_nervous3.42928164
7MP0003880_abnormal_central_pattern3.40408574
8MP0002210_abnormal_sex_determination3.37845520
9MP0002653_abnormal_ependyma_morphology3.37463025
10MP0002161_abnormal_fertility/fecundity3.22554869
11MP0001145_abnormal_male_reproductive2.82110510
12MP0001348_abnormal_lacrimal_gland2.63833323
13MP0003635_abnormal_synaptic_transmissio2.61081227
14MP0005670_abnormal_white_adipose2.60724774
15MP0002064_seizures2.58881158
16MP0001486_abnormal_startle_reflex2.54517287
17MP0000653_abnormal_sex_gland2.50433802
18MP0004510_myositis2.45947631
19MP0009745_abnormal_behavioral_response2.38799640
20MP0002160_abnormal_reproductive_system2.10467990
21MP0008438_abnormal_cutaneous_collagen2.07402815
22MP0005410_abnormal_fertilization15.8448120
23MP0001984_abnormal_olfaction1.90308436
24MP0005275_abnormal_skin_tensile1.86834723
25MP0003123_paternal_imprinting1.85518770
26MP0002734_abnormal_mechanical_nocicepti1.84667564
27MP0009780_abnormal_chondrocyte_physiolo1.75292849
28MP0008569_lethality_at_weaning1.72617911
29MP0002067_abnormal_sensory_capabilities1.68773211
30MP0009053_abnormal_anal_canal1.68603401
31MP0001501_abnormal_sleep_pattern1.64460579
32MP0001970_abnormal_pain_threshold1.63045199
33MP0005623_abnormal_meninges_morphology1.60047914
34MP0002733_abnormal_thermal_nociception1.54435344
35MP0000920_abnormal_myelination1.50583522
36MP0001963_abnormal_hearing_physiology1.25018722
37MP0001986_abnormal_taste_sensitivity1.21405600
38MP0001485_abnormal_pinna_reflex1.20726909
39MP0001440_abnormal_grooming_behavior1.18207062
40MP0002102_abnormal_ear_morphology1.17761152
41MP0003283_abnormal_digestive_organ1.16803429
42MP0002282_abnormal_trachea_morphology1.16336513
43MP0003690_abnormal_glial_cell1.15990659
44MP0003646_muscle_fatigue1.13677692
45MP0005409_darkened_coat_color1.13172981
46MP0000751_myopathy1.12948579
47MP0006276_abnormal_autonomic_nervous1.11566708
48MP0005310_abnormal_salivary_gland1.10385122
49MP0008058_abnormal_DNA_repair1.06048733
50MP0001765_abnormal_ion_homeostasis1.06023743
51MP0004233_abnormal_muscle_weight1.05843415
52MP0002066_abnormal_motor_capabilities/c1.05710488
53MP0001958_emphysema1.05130439
54MP0005389_reproductive_system_phenotype1.04436256
55MP0008995_early_reproductive_senescence1.02667669
56MP0002295_abnormal_pulmonary_circulatio1.02413198
57MP0005451_abnormal_body_composition1.01811160
58MP0005508_abnormal_skeleton_morphology1.00005843
59MP0009046_muscle_twitch0.98120951
60MP0010386_abnormal_urinary_bladder0.98009398
61MP0000604_amyloidosis0.97815574
62MP0003137_abnormal_impulse_conducting0.95449766
63MP0004085_abnormal_heartbeat0.91318642
64MP0002234_abnormal_pharynx_morphology0.90225129
65MP0005647_abnormal_sex_gland0.89744471
66MP0005551_abnormal_eye_electrophysiolog0.88914629
67MP0001299_abnormal_eye_distance/0.88550359
68MP0008874_decreased_physiological_sensi0.84326286
69MP0001293_anophthalmia0.83644719
70MP0001905_abnormal_dopamine_level0.81983310
71MP0004142_abnormal_muscle_tone0.81881619
72MP0003279_aneurysm0.79225038
73MP0002736_abnormal_nociception_after0.77733067
74MP0004885_abnormal_endolymph0.77464056
75MP0005379_endocrine/exocrine_gland_phen0.77299398
76MP0001324_abnormal_eye_pigmentation0.75791891
77MP0005394_taste/olfaction_phenotype0.75673286
78MP0005499_abnormal_olfactory_system0.75673286
79MP0002638_abnormal_pupillary_reflex0.74655966
80MP0004742_abnormal_vestibular_system0.73646314
81MP0005535_abnormal_body_temperature0.73269597
82MP0003115_abnormal_respiratory_system0.71232113
83MP0004270_analgesia0.71092153
84MP0008789_abnormal_olfactory_epithelium0.70752124
85MP0001502_abnormal_circadian_rhythm0.70621805
86MP0003121_genomic_imprinting0.66024832
87MP0005390_skeleton_phenotype0.65947202
88MP0004133_heterotaxia0.65759306
89MP0000681_abnormal_thyroid_gland0.64023393
90MP0003385_abnormal_body_wall0.63936786
91MP0002163_abnormal_gland_morphology0.63243006
92MP0002933_joint_inflammation0.62933443
93MP0005386_behavior/neurological_phenoty0.59836468
94MP0004924_abnormal_behavior0.59836468
95MP0002928_abnormal_bile_duct0.59436334
96MP0003861_abnormal_nervous_system0.58918463
97MP0005377_hearing/vestibular/ear_phenot0.57637926
98MP0003878_abnormal_ear_physiology0.57637926
99MP0001968_abnormal_touch/_nociception0.51762487
100MP0004019_abnormal_vitamin_homeostasis0.51616595
101MP0010094_abnormal_chromosome_stability0.50978107
102MP0005391_vision/eye_phenotype0.49222770
103MP0005636_abnormal_mineral_homeostasis0.47000102
104MP0002152_abnormal_brain_morphology0.46493310
105MP0005253_abnormal_eye_physiology0.45900300
106MP0003699_abnormal_female_reproductive0.43357202
107MP0003942_abnormal_urinary_system0.42413176
108MP0004811_abnormal_neuron_physiology0.41920129
109MP0002092_abnormal_eye_morphology0.40976660
110MP0000778_abnormal_nervous_system0.40718934
111MP0008057_abnormal_DNA_replication0.39693347
112MP0001119_abnormal_female_reproductive0.38787644
113MP0002735_abnormal_chemical_nociception0.37964077
114MP0000358_abnormal_cell_content/0.37422883
115MP0002557_abnormal_social/conspecific_i0.37004176
116MP0009115_abnormal_fat_cell0.36878629
117MP0000569_abnormal_digit_pigmentation0.36601057
118MP0005666_abnormal_adipose_tissue0.35945638
119MP0001764_abnormal_homeostasis0.34942926
120MP0002971_abnormal_brown_adipose0.34617056
121MP0002752_abnormal_somatic_nervous0.34550222
122MP0003948_abnormal_gas_homeostasis0.33956475
123MP0005645_abnormal_hypothalamus_physiol0.32394313
124MP0005195_abnormal_posterior_eye0.32277446
125MP0000955_abnormal_spinal_cord0.31508683
126MP0002882_abnormal_neuron_morphology0.31312295
127MP0003633_abnormal_nervous_system0.31302795
128MP0003011_delayed_dark_adaptation0.30847547
129MP0002572_abnormal_emotion/affect_behav0.30150209
130MP0002693_abnormal_pancreas_physiology0.25937769
131MP0003787_abnormal_imprinting0.25631499
132MP0001545_abnormal_hematopoietic_system0.25607896
133MP0005397_hematopoietic_system_phenotyp0.25607896
134MP0003631_nervous_system_phenotype0.25226693
135MP0001529_abnormal_vocalization0.25202041
136MP0009672_abnormal_birth_weight0.25188115
137MP0005174_abnormal_tail_pigmentation0.24187276
138MP0009703_decreased_birth_body0.23965199
139MP0002063_abnormal_learning/memory/cond0.23380493
140MP0003111_abnormal_nucleus_morphology0.22196992
141MP0002108_abnormal_muscle_morphology0.22143558
142MP0000026_abnormal_inner_ear0.21781651
143MP0009278_abnormal_bone_marrow0.21050278
144MP0002229_neurodegeneration0.20891851
145MP0001727_abnormal_embryo_implantation0.20814765
146MP0002169_no_abnormal_phenotype0.20781803
147MP0002873_normal_phenotype0.20445509
148MP0002132_abnormal_respiratory_system0.20052906
149MP0000432_abnormal_head_morphology0.19716096
150MP0003936_abnormal_reproductive_system0.19604015
151MP0003879_abnormal_hair_cell0.19370241
152MP0000534_abnormal_ureter_morphology0.19293619
153MP0003786_premature_aging0.19214497
154MP0003329_amyloid_beta_deposits0.18935123
155MP0002184_abnormal_innervation0.18470930
156MP0002272_abnormal_nervous_system0.18083950
157MP0002233_abnormal_nose_morphology0.16778326
158MP0005365_abnormal_bile_salt0.16638977
159MP0005646_abnormal_pituitary_gland0.16514059

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.10131025
2Abnormal respiratory epithelium morphology (HP:0012253)8.86759644
3Abnormal respiratory motile cilium morphology (HP:0005938)8.86759644
4Rhinitis (HP:0012384)7.55134736
5Abnormal ciliary motility (HP:0012262)7.12493481
6Chronic bronchitis (HP:0004469)7.09578696
7Infertility (HP:0000789)6.22098373
8Nasal polyposis (HP:0100582)5.86769663
9Myokymia (HP:0002411)5.41618510
10Focal motor seizures (HP:0011153)5.11876564
11Slow saccadic eye movements (HP:0000514)5.00048915
12Abnormality of the nasal mucosa (HP:0000433)4.79022235
13Metaphyseal dysplasia (HP:0100255)4.67946393
14Severe visual impairment (HP:0001141)4.65128146
15Nephronophthisis (HP:0000090)4.45564071
16Focal seizures (HP:0007359)4.42503135
17Bronchitis (HP:0012387)4.40124453
18Bronchiectasis (HP:0002110)4.31015959
19Atonic seizures (HP:0010819)4.22070176
20Action tremor (HP:0002345)4.15646742
21Male infertility (HP:0003251)3.97945832
22Abnormality of the renal medulla (HP:0100957)3.49654375
23Abnormality of saccadic eye movements (HP:0000570)3.37758569
24Absence seizures (HP:0002121)3.30935033
25Febrile seizures (HP:0002373)3.27163845
26Abnormal spermatogenesis (HP:0008669)3.23708964
27Visual hallucinations (HP:0002367)3.19407883
28Recurrent sinusitis (HP:0011108)3.16222287
29Recurrent otitis media (HP:0000403)3.15382635
30Hypoplastic ischia (HP:0003175)3.06821359
31Peripheral hypomyelination (HP:0007182)3.05686426
32Supranuclear gaze palsy (HP:0000605)3.05555008
33Postural instability (HP:0002172)3.03827787
34Molar tooth sign on MRI (HP:0002419)3.01935169
35Abnormality of midbrain morphology (HP:0002418)3.01935169
36Tubulointerstitial nephritis (HP:0001970)2.97800699
37Dialeptic seizures (HP:0011146)2.96532234
38Tongue fasciculations (HP:0001308)2.96435418
39Nuclear cataract (HP:0100018)2.94637062
40Anomalous pulmonary venous return (HP:0010772)2.87740042
41Abnormality of the ischium (HP:0003174)2.81462666
42Papilledema (HP:0001085)2.81120594
43Abnormality of the pulmonary veins (HP:0011718)2.77277979
44Resting tremor (HP:0002322)2.76977307
45Epileptic encephalopathy (HP:0200134)2.75752726
46Impaired smooth pursuit (HP:0007772)2.73393487
47Ulnar claw (HP:0001178)2.73222965
48Abnormality of binocular vision (HP:0011514)2.72135245
49Diplopia (HP:0000651)2.72135245
50Medial flaring of the eyebrow (HP:0010747)2.71694267
51Impulsivity (HP:0100710)2.64504255
52Dyschromatopsia (HP:0007641)2.60888866
53Recurrent bronchitis (HP:0002837)2.60488290
54Muscle fibrillation (HP:0010546)2.56170737
55Bundle branch block (HP:0011710)2.49535213
56Enlarged epiphyses (HP:0010580)2.47490968
57Bradykinesia (HP:0002067)2.41795211
58Tubulointerstitial abnormality (HP:0001969)2.38979483
59Postaxial foot polydactyly (HP:0001830)2.36148677
60Generalized tonic-clonic seizures (HP:0002069)2.34648120
61Tubular atrophy (HP:0000092)2.34418789
62Delusions (HP:0000746)2.34306279
63Abnormality of ocular smooth pursuit (HP:0000617)2.27425283
64Asymmetric septal hypertrophy (HP:0001670)2.27394154
65Limb dystonia (HP:0002451)2.27182933
66Torticollis (HP:0000473)2.26994506
67Gonadotropin excess (HP:0000837)2.26820782
68Neonatal hypoglycemia (HP:0001998)2.25914805
69Overgrowth (HP:0001548)2.25698022
70Abnormality of dental color (HP:0011073)2.22966434
71Focal dystonia (HP:0004373)2.22724430
72Abnormality of the aortic arch (HP:0012303)2.22583714
73Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.21435209
74Amblyopia (HP:0000646)2.20527902
75Pancreatic fibrosis (HP:0100732)2.19368077
76Choroideremia (HP:0001139)2.14474997
77Decreased central vision (HP:0007663)2.14132221
78Bulbous nose (HP:0000414)2.12825279
79Abnormality of macular pigmentation (HP:0008002)2.11173330
80Rapidly progressive (HP:0003678)2.10987953
81Intention tremor (HP:0002080)2.10604524
82Craniofacial dystonia (HP:0012179)2.10053715
83Epiphyseal dysplasia (HP:0002656)2.09247123
84Limb ataxia (HP:0002070)2.08838637
85Azoospermia (HP:0000027)2.06998760
86Bony spicule pigmentary retinopathy (HP:0007737)2.05418877
87Cerebral hypomyelination (HP:0006808)2.05370511
88Dysmetria (HP:0001310)2.04379592
89Congenital hepatic fibrosis (HP:0002612)2.02710325
90Abnormality of the lower motor neuron (HP:0002366)2.02485415
91Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0559484
92Dynein arm defect of respiratory motile cilia (HP:0012255)12.7963624
93Absent/shortened dynein arms (HP:0200106)12.7963624
94Abnormal pancreas size (HP:0012094)1.97900377
95Atrophic scars (HP:0001075)1.96618227
96Rigidity (HP:0002063)1.95541996
97Hyperthyroidism (HP:0000836)1.95521791
98Status epilepticus (HP:0002133)1.92209898
99Heterotopia (HP:0002282)1.91348415
100Decreased motor nerve conduction velocity (HP:0003431)1.90688444
101Abnormality of the renal cortex (HP:0011035)1.89448259
102Bile duct proliferation (HP:0001408)1.89233127
103Abnormal biliary tract physiology (HP:0012439)1.89233127
104Atelectasis (HP:0100750)1.88195380
105Renal Fanconi syndrome (HP:0001994)1.87810047
106Global brain atrophy (HP:0002283)1.86737418
107Short ribs (HP:0000773)1.86165569
108Neurofibrillary tangles (HP:0002185)1.86156608
109Congenital primary aphakia (HP:0007707)1.80884185
110Aplasia/Hypoplasia of the lens (HP:0008063)1.80730441
111Gait imbalance (HP:0002141)1.80646261
112Sensory axonal neuropathy (HP:0003390)1.80002742
113Stage 5 chronic kidney disease (HP:0003774)1.79802189
114Pigmentary retinal degeneration (HP:0001146)1.79631161
115Abnormal eating behavior (HP:0100738)1.79366968
116Hemorrhage of the eye (HP:0011885)1.79233826
117Protrusio acetabuli (HP:0003179)1.79207391
118Premature rupture of membranes (HP:0001788)1.78925851
119Tubulointerstitial fibrosis (HP:0005576)1.78797863
120Stereotypic behavior (HP:0000733)1.78250284
121Hypoplastic left heart (HP:0004383)1.78118467
122Bell-shaped thorax (HP:0001591)1.77270639
123Spastic tetraparesis (HP:0001285)1.76624996
124Hyperkalemia (HP:0002153)1.75787369
125Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.75526925
126Abnormality of the frontal sinuses (HP:0002687)1.75463087
127Postaxial hand polydactyly (HP:0001162)1.75185871
128Cerebral inclusion bodies (HP:0100314)1.73860889
129Adrenal hypoplasia (HP:0000835)1.71225368
130Abnormal gallbladder physiology (HP:0012438)1.71136984
131Cholecystitis (HP:0001082)1.71136984
132Upper limb muscle weakness (HP:0003484)1.70843364
133Abnormality of the dental root (HP:0006486)1.69659352
134Taurodontia (HP:0000679)1.69659352
135Abnormality of permanent molar morphology (HP:0011071)1.69659352
136Facial cleft (HP:0002006)1.68796830
137Ventricular tachycardia (HP:0004756)1.68723845
138Flattened epiphyses (HP:0003071)1.68458493
139Neonatal short-limb short stature (HP:0008921)1.67173425
140Fetal akinesia sequence (HP:0001989)1.66875683
141Oculomotor apraxia (HP:0000657)1.66329218
142Microglossia (HP:0000171)1.66050119
143Ectopia lentis (HP:0001083)1.65766712
144Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.65691594
145Cervical subluxation (HP:0003308)1.64674237
146Cystic liver disease (HP:0006706)1.64567119
147Decreased electroretinogram (ERG) amplitude (HP:0000654)1.62310369
148Median cleft lip (HP:0000161)1.61933107
149Double outlet right ventricle (HP:0001719)1.60967339
150Congenital malformation of the right heart (HP:0011723)1.60967339
151Renal dysplasia (HP:0000110)1.60826314
152Fibular hypoplasia (HP:0003038)1.60822204
153Abnormality of molar morphology (HP:0011070)1.60201805
154Abnormality of molar (HP:0011077)1.60201805
155Deformed sella turcica (HP:0002681)1.60133008
156Hypoplasia of the capital femoral epiphysis (HP:0003090)1.59029694
157Abnormality of dentin (HP:0010299)1.58699738
158Supernumerary spleens (HP:0009799)1.57613298
159Abnormal drinking behavior (HP:0030082)1.56408494
160Polydipsia (HP:0001959)1.56408494
161Genital tract atresia (HP:0001827)1.55044580
162Nephrogenic diabetes insipidus (HP:0009806)1.54921515
163Abnormality of renal excretion (HP:0011036)1.54241923
164Aplasia/Hypoplasia of the tongue (HP:0010295)1.53116887
165Abnormality of the dental pulp (HP:0006479)1.52789392
166Amyotrophic lateral sclerosis (HP:0007354)1.52705647
167Truncal obesity (HP:0001956)1.49577849
168Short thorax (HP:0010306)1.47576931
169Absent frontal sinuses (HP:0002688)1.47170211
170Chronic sinusitis (HP:0011109)1.45791481
171Poor coordination (HP:0002370)1.43377996
172Chronic hepatic failure (HP:0100626)1.42290821
173Nephropathy (HP:0000112)1.38958766
174Vaginal atresia (HP:0000148)1.38712455
175True hermaphroditism (HP:0010459)1.35466347
176Pachygyria (HP:0001302)1.33998380
177Renovascular hypertension (HP:0100817)1.33225127
178J-shaped sella turcica (HP:0002680)1.32349652
179Progressive cerebellar ataxia (HP:0002073)1.30091649
180Hemiparesis (HP:0001269)1.24976213
181Lissencephaly (HP:0001339)1.23119787
182Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.22544672
183Absent epiphyses (HP:0010577)1.22544672
184Retinal dysplasia (HP:0007973)1.22499052
185Hypercholesterolemia (HP:0003124)1.20615483
186Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.20219190

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.88594636
2PDK37.88594636
3TESK15.89130258
4PDK25.07236176
5PRKD34.70590342
6ICK4.25528862
7PNCK2.89250383
8EPHA42.85661672
9PLK22.73352033
10PAK62.72268634
11SIK22.59716751
12UHMK12.38894168
13LATS22.38315605
14BLK2.29179392
15PAK32.27945936
16PTK2B2.25856034
17WNK42.19245946
18STK392.12218555
19TAOK21.95726959
20DYRK1B1.82209276
21CAMK11.79989059
22MAP2K61.76370591
23MAP3K111.75766378
24STK381.59467847
25INSRR1.53289830
26GRK51.48656891
27NTRK11.39003071
28DMPK1.32488241
29NEK21.32367118
30PDK11.27962892
31PRPF4B1.22822399
32SIK31.20602479
33BRD41.19135393
34ABL21.16233148
35WNK11.16095170
36PIK3CG1.14898144
37GRK71.09293525
38KSR21.07617975
39EPHB11.05345713
40MYLK1.04712278
41AKT31.02256368
42EEF2K1.00662252
43MAPK151.00153806
44MAP4K20.97981672
45DAPK20.97924566
46TYRO30.94733277
47CAMK40.92718012
48CAMK1G0.84531436
49CAMKK20.84357257
50CDK50.84023043
51PDPK10.84008497
52MAP2K40.83821255
53MAP3K50.81747908
54PLK40.81686676
55DYRK30.78054182
56MAP3K120.76414384
57MAP3K10.74813594
58ARAF0.73953828
59MAPK120.72883661
60JAK10.70283765
61NTRK20.70242578
62PRKCH0.69335121
63TNK20.69258691
64CHEK20.68190890
65TTK0.64284485
66SGK30.62617511
67PDGFRA0.60902969
68IRAK10.59275612
69PASK0.58578410
70MOS0.57559620
71SIK10.57284338
72MAP3K90.55613107
73PINK10.55093034
74CDK120.52448899
75CAMK2G0.52077285
76MAPK100.50932821
77MARK30.50598150
78STK30.50257180
79CAMK2B0.48597827
80RET0.48208149
81PRKD10.48142610
82MAPK40.47805313
83CAMK2D0.46403932
84CDK140.46297721
85PRKG20.45945741
86CAMK1D0.44955352
87SGK10.44675410
88MAPKAPK50.44173502
89PRKCG0.42229766
90RIPK10.40511191
91ALK0.39885112
92TIE10.36446397
93TNIK0.35985170
94CHEK10.35900406
95MTOR0.35870889
96RPS6KA30.35338456
97NEK60.34544397
98BMPR20.34283685
99ROCK10.33322004
100SYK0.33266808
101MATK0.33096578
102MAP2K30.32668170
103LMTK20.32556272
104TESK20.32275225
105RIPK40.32119743
106ATM0.31285149
107PAK10.29240014
108MARK20.27886663
109ATR0.26115739
110RPS6KB10.26053352
111CCNB10.23837534
112PKN10.22054790
113GRK10.21772532
114PAK20.20705873
115MAP3K100.20547434
116MARK10.20200673
117STK38L0.19472041
118SRPK10.19191416
119WEE10.18389186
120MAP2K70.18092935
121IRAK20.17813068
122YES10.17808650
123MAPK80.17317189
124MINK10.14786540
125PRKCZ0.14406934
126MAPKAPK30.13607615
127EPHB20.13360080
128PRKAA10.13223758
129PLK10.12926218
130GSK3B0.12193114
131CAMK2A0.11677195
132PAK40.11594052
133PRKCQ0.11124571
134BMPR1B0.10449589
135MAPK130.10022958
136BRAF0.09541361
137STK110.08945180
138PRKCB0.08904371
139CSNK1D0.08298690
140PRKG10.07589669
141CSNK2A10.07506839
142CDK90.07191768
143RPS6KA10.07123299
144MUSK0.06720438
145CDK150.06199911
146SGK2230.06009778
147SGK4940.06009778
148CDK180.05783865
149CDK10.05693037
150CAMKK10.05397703
151PIM10.04142054
152SGK20.03872854
153MAP3K40.03706475
154DDR20.02344947
155CSF1R0.02221391
156CDK11A0.01886052
157CDK20.01430771
158CSNK2A20.00828643
159NTRK30.00599517
160PDGFRB0.00413818
161PRKCA-0.0038972
162ZAK-0.0015837
163PRKACB-0.0006906

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.59315455
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.07211609
3Vitamin B6 metabolism_Homo sapiens_hsa007503.76866908
4Nicotine addiction_Homo sapiens_hsa050333.40103068
5Pyruvate metabolism_Homo sapiens_hsa006203.17538663
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.91849030
7Linoleic acid metabolism_Homo sapiens_hsa005912.84949514
8Glucagon signaling pathway_Homo sapiens_hsa049222.67283172
9Propanoate metabolism_Homo sapiens_hsa006402.48781820
10Morphine addiction_Homo sapiens_hsa050322.36921341
11Dorso-ventral axis formation_Homo sapiens_hsa043202.31176090
12GABAergic synapse_Homo sapiens_hsa047272.23214616
13Basal transcription factors_Homo sapiens_hsa030222.15607204
14Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.14557147
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.13692510
16Carbohydrate digestion and absorption_Homo sapiens_hsa049731.99756654
17Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.97959116
18Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.91309243
19Glycerolipid metabolism_Homo sapiens_hsa005611.86563419
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.86520978
21Selenocompound metabolism_Homo sapiens_hsa004501.86465298
22Oocyte meiosis_Homo sapiens_hsa041141.83372861
23PPAR signaling pathway_Homo sapiens_hsa033201.83312071
24Amphetamine addiction_Homo sapiens_hsa050311.82397937
25Fanconi anemia pathway_Homo sapiens_hsa034601.74523027
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73311889
27Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.59526198
28Cholinergic synapse_Homo sapiens_hsa047251.57606934
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.54981380
30Oxytocin signaling pathway_Homo sapiens_hsa049211.49435113
31Mineral absorption_Homo sapiens_hsa049781.48502573
32Glycerophospholipid metabolism_Homo sapiens_hsa005641.39235891
33Ether lipid metabolism_Homo sapiens_hsa005651.36568089
34Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.30303743
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.28809690
36mRNA surveillance pathway_Homo sapiens_hsa030151.28113676
37Glycosaminoglycan degradation_Homo sapiens_hsa005311.27716276
38Collecting duct acid secretion_Homo sapiens_hsa049661.25037590
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.24924309
40Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.24741857
41Olfactory transduction_Homo sapiens_hsa047401.24719708
42GnRH signaling pathway_Homo sapiens_hsa049121.19888951
43Cardiac muscle contraction_Homo sapiens_hsa042601.19287302
44Fatty acid degradation_Homo sapiens_hsa000711.15397944
45Hedgehog signaling pathway_Homo sapiens_hsa043401.13751253
46Fat digestion and absorption_Homo sapiens_hsa049751.13588522
47Pentose phosphate pathway_Homo sapiens_hsa000301.11940686
48Huntingtons disease_Homo sapiens_hsa050161.11451278
49Dilated cardiomyopathy_Homo sapiens_hsa054141.10627465
50Renin secretion_Homo sapiens_hsa049241.09947758
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08779638
52Fatty acid metabolism_Homo sapiens_hsa012121.07776228
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.06059142
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04020838
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.97770621
56Long-term potentiation_Homo sapiens_hsa047200.96390941
57Regulation of autophagy_Homo sapiens_hsa041400.95283346
58Fructose and mannose metabolism_Homo sapiens_hsa000510.95126323
59Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93590336
60Insulin secretion_Homo sapiens_hsa049110.92290575
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.91824811
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90943064
63MAPK signaling pathway_Homo sapiens_hsa040100.87421304
64Purine metabolism_Homo sapiens_hsa002300.85129326
65Circadian entrainment_Homo sapiens_hsa047130.84502932
66Antigen processing and presentation_Homo sapiens_hsa046120.84367925
67Gap junction_Homo sapiens_hsa045400.84175993
68Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.82655050
69Phenylalanine metabolism_Homo sapiens_hsa003600.82251627
70Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.81444570
71Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81174857
72Osteoclast differentiation_Homo sapiens_hsa043800.80598532
73Serotonergic synapse_Homo sapiens_hsa047260.80157518
74Type II diabetes mellitus_Homo sapiens_hsa049300.76542220
75Synaptic vesicle cycle_Homo sapiens_hsa047210.76078135
76Carbon metabolism_Homo sapiens_hsa012000.75253359
77ABC transporters_Homo sapiens_hsa020100.74474380
78Melanogenesis_Homo sapiens_hsa049160.73492774
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.71945228
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.71691365
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.71643016
82Taste transduction_Homo sapiens_hsa047420.71358889
83Arachidonic acid metabolism_Homo sapiens_hsa005900.71202654
84Adipocytokine signaling pathway_Homo sapiens_hsa049200.70403947
85Other glycan degradation_Homo sapiens_hsa005110.69827530
86Calcium signaling pathway_Homo sapiens_hsa040200.69577716
87Estrogen signaling pathway_Homo sapiens_hsa049150.67850459
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.66893823
89RNA transport_Homo sapiens_hsa030130.66212259
90Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64990703
91Rap1 signaling pathway_Homo sapiens_hsa040150.64237735
92Arginine and proline metabolism_Homo sapiens_hsa003300.64059164
93Prion diseases_Homo sapiens_hsa050200.63523343
94cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61092370
95Bile secretion_Homo sapiens_hsa049760.59266936
96Sphingolipid signaling pathway_Homo sapiens_hsa040710.58507651
97Vibrio cholerae infection_Homo sapiens_hsa051100.57939181
98Chemical carcinogenesis_Homo sapiens_hsa052040.55958650
99Long-term depression_Homo sapiens_hsa047300.55753852
100Systemic lupus erythematosus_Homo sapiens_hsa053220.55478333
101AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55433161
102Glioma_Homo sapiens_hsa052140.55428503
103N-Glycan biosynthesis_Homo sapiens_hsa005100.55367522
104Platelet activation_Homo sapiens_hsa046110.55155245
105Circadian rhythm_Homo sapiens_hsa047100.52866783
106Glutathione metabolism_Homo sapiens_hsa004800.51382781
107Basal cell carcinoma_Homo sapiens_hsa052170.51123070
108Glutamatergic synapse_Homo sapiens_hsa047240.50093040
109Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50009488
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49597960
111cAMP signaling pathway_Homo sapiens_hsa040240.48195343
112Thyroid hormone synthesis_Homo sapiens_hsa049180.47719050
113ECM-receptor interaction_Homo sapiens_hsa045120.47342650
114Cocaine addiction_Homo sapiens_hsa050300.45831530
115Influenza A_Homo sapiens_hsa051640.44420131
116Salivary secretion_Homo sapiens_hsa049700.43947946
117Phagosome_Homo sapiens_hsa041450.43655503
118Phototransduction_Homo sapiens_hsa047440.43064444
119Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.41892462
120Alcoholism_Homo sapiens_hsa050340.40763526
121Toll-like receptor signaling pathway_Homo sapiens_hsa046200.40428577
122Legionellosis_Homo sapiens_hsa051340.39994537
123Phosphatidylinositol signaling system_Homo sapiens_hsa040700.39945975
124ErbB signaling pathway_Homo sapiens_hsa040120.39130069
125Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.39073339
126Pancreatic secretion_Homo sapiens_hsa049720.38871713
127FoxO signaling pathway_Homo sapiens_hsa040680.38822118
128Wnt signaling pathway_Homo sapiens_hsa043100.38763783
129Protein digestion and absorption_Homo sapiens_hsa049740.38206795
130Ras signaling pathway_Homo sapiens_hsa040140.38031683
131Biosynthesis of amino acids_Homo sapiens_hsa012300.37986889
132Vascular smooth muscle contraction_Homo sapiens_hsa042700.37692679
133Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.36841841
134Prolactin signaling pathway_Homo sapiens_hsa049170.36679220
135Thyroid hormone signaling pathway_Homo sapiens_hsa049190.36445172
136Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.35914214
137Chemokine signaling pathway_Homo sapiens_hsa040620.35716427
138Gastric acid secretion_Homo sapiens_hsa049710.34849089
139Dopaminergic synapse_Homo sapiens_hsa047280.34569080
140Renin-angiotensin system_Homo sapiens_hsa046140.33355131
141Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32011195
142Endocytosis_Homo sapiens_hsa041440.31218289
143VEGF signaling pathway_Homo sapiens_hsa043700.30987135
144Salmonella infection_Homo sapiens_hsa051320.29907341
145Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29658673
146Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26471630
147Metabolic pathways_Homo sapiens_hsa011000.26002070
148Inositol phosphate metabolism_Homo sapiens_hsa005620.25615813
149Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.23464628
150Sphingolipid metabolism_Homo sapiens_hsa006000.20959706
151AMPK signaling pathway_Homo sapiens_hsa041520.20279516
152RNA degradation_Homo sapiens_hsa030180.20172945
153Axon guidance_Homo sapiens_hsa043600.20133840

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »