TEX35

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.61113334
2spermatid development (GO:0007286)9.57062097
3axonemal dynein complex assembly (GO:0070286)9.55670149
4cilium or flagellum-dependent cell motility (GO:0001539)9.41321708
5cilium movement (GO:0003341)8.04505757
6regulation of cilium movement (GO:0003352)7.80721509
7single fertilization (GO:0007338)7.65833223
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.53495370
9sperm capacitation (GO:0048240)7.18911280
10male meiosis (GO:0007140)7.01202243
11synaptonemal complex organization (GO:0070193)6.90438755
12synaptonemal complex assembly (GO:0007130)6.84505886
13negative regulation of inclusion body assembly (GO:0090084)6.70736993
14microtubule depolymerization (GO:0007019)6.69753813
15piRNA metabolic process (GO:0034587)6.63024636
16spermatogenesis (GO:0007283)6.46631835
17male gamete generation (GO:0048232)6.44275039
18fertilization (GO:0009566)6.34631517
19spermatid nucleus differentiation (GO:0007289)6.27059856
20organic cation transport (GO:0015695)6.11836107
21gamete generation (GO:0007276)5.95626204
22regulation of inclusion body assembly (GO:0090083)5.62380789
23calcium ion-dependent exocytosis (GO:0017156)5.60595132
24germ cell development (GO:0007281)5.29469486
25response to pheromone (GO:0019236)5.28854683
26cellular process involved in reproduction in multicellular organism (GO:0022412)5.25704757
27cell recognition (GO:0008037)5.11661694
28glycerol ether metabolic process (GO:0006662)5.09815268
29sexual reproduction (GO:0019953)5.00190775
30ventricular system development (GO:0021591)4.91306363
31chromosome condensation (GO:0030261)4.87570578
32single strand break repair (GO:0000012)4.80829120
33establishment of protein localization to Golgi (GO:0072600)4.79612361
34ether metabolic process (GO:0018904)4.71087478
35chromosome organization involved in meiosis (GO:0070192)4.69968956
36multicellular organismal reproductive process (GO:0048609)4.68520853
37detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.61214217
38microtubule severing (GO:0051013)4.60486062
39DNA packaging (GO:0006323)4.54587735
40regulation of microtubule-based movement (GO:0060632)4.54179141
41male meiosis I (GO:0007141)4.42854176
42cellular ketone body metabolic process (GO:0046950)4.36763009
43DNA methylation involved in gamete generation (GO:0043046)4.31887560
44tryptophan catabolic process (GO:0006569)4.26248116
45indole-containing compound catabolic process (GO:0042436)4.26248116
46indolalkylamine catabolic process (GO:0046218)4.26248116
47indolalkylamine metabolic process (GO:0006586)4.24461378
48meiotic nuclear division (GO:0007126)4.16353187
49seminiferous tubule development (GO:0072520)4.13952111
50protein targeting to Golgi (GO:0000042)3.97877466
51chaperone-mediated protein complex assembly (GO:0051131)3.94877588
52detection of light stimulus involved in visual perception (GO:0050908)3.93968093
53detection of light stimulus involved in sensory perception (GO:0050962)3.93968093
54protein K11-linked deubiquitination (GO:0035871)3.92684379
55ketone body metabolic process (GO:1902224)3.87127206
56photoreceptor cell maintenance (GO:0045494)3.86108321
57monoubiquitinated protein deubiquitination (GO:0035520)3.80517594
58multicellular organismal development (GO:0007275)3.76780553
59neural tube formation (GO:0001841)3.75208469
60left/right pattern formation (GO:0060972)3.69609194
61retrograde transport, vesicle recycling within Golgi (GO:0000301)3.63444553
62kynurenine metabolic process (GO:0070189)3.63348295
63tryptophan metabolic process (GO:0006568)3.58453972
64microtubule polymerization or depolymerization (GO:0031109)3.54865378
65meiosis I (GO:0007127)3.52123945
66regulation of sarcomere organization (GO:0060297)3.45770128
67genitalia morphogenesis (GO:0035112)3.41283189
68signal peptide processing (GO:0006465)3.36622931
69DNA double-strand break processing (GO:0000729)3.35605585
70protein K48-linked deubiquitination (GO:0071108)3.33178213
71tachykinin receptor signaling pathway (GO:0007217)3.31980587
72sequestering of actin monomers (GO:0042989)3.29830836
73NAD biosynthetic process (GO:0009435)3.27034729
74protein polyglutamylation (GO:0018095)3.21019279
75reflex (GO:0060004)3.20335475
76meiotic cell cycle (GO:0051321)3.20334228
77centriole assembly (GO:0098534)3.19279544
78retinal cone cell development (GO:0046549)3.10420219
79nucleus organization (GO:0006997)3.10133840
80negative regulation of mast cell activation (GO:0033004)3.08953764
81glycolytic process (GO:0006096)3.07449363
82regulation of spindle checkpoint (GO:0090231)3.06899441
83alditol metabolic process (GO:0019400)3.06199229
84L-fucose catabolic process (GO:0042355)3.04501226
85fucose catabolic process (GO:0019317)3.04501226
86L-fucose metabolic process (GO:0042354)3.04501226
87indole-containing compound metabolic process (GO:0042430)3.04345387
88protein prenylation (GO:0018342)3.01875100
89prenylation (GO:0097354)3.01875100
90protein localization to Golgi apparatus (GO:0034067)3.01648236
91polyol catabolic process (GO:0046174)2.99955198
92protein K63-linked deubiquitination (GO:0070536)2.99373930
93protein refolding (GO:0042026)2.99270963
94auditory receptor cell stereocilium organization (GO:0060088)2.98713944
95behavioral response to ethanol (GO:0048149)2.98442668
96cellular biogenic amine catabolic process (GO:0042402)2.94098089
97amine catabolic process (GO:0009310)2.94098089
98negative regulation of calcium ion transport into cytosol (GO:0010523)2.93425543
99detection of mechanical stimulus involved in sensory perception (GO:0050974)2.93236313
100positive regulation of macrophage activation (GO:0043032)2.93034926
101mitotic sister chromatid cohesion (GO:0007064)2.90585065
102nucleoside diphosphate phosphorylation (GO:0006165)2.90292915
103regulation of hippo signaling (GO:0035330)2.88488994
104double-strand break repair via homologous recombination (GO:0000724)2.87007336
105recombinational repair (GO:0000725)2.84248267
106cilium organization (GO:0044782)2.83779460
107amino-acid betaine transport (GO:0015838)2.82565261
108carnitine transport (GO:0015879)2.82565261
109centriole replication (GO:0007099)2.80886494
110nonmotile primary cilium assembly (GO:0035058)2.78728120
111GTP biosynthetic process (GO:0006183)2.77321485
112cilium assembly (GO:0042384)2.75611619
113protein localization to cilium (GO:0061512)2.75595532
114negative regulation of cytosolic calcium ion concentration (GO:0051481)2.73787907
115meiotic cell cycle process (GO:1903046)2.73059426
116cellular component assembly involved in morphogenesis (GO:0010927)2.72516505
117primary amino compound metabolic process (GO:1901160)2.72046519
118synapsis (GO:0007129)2.70790011
119microtubule-based movement (GO:0007018)2.70094470
120behavioral response to nicotine (GO:0035095)2.70045612
121chromatin silencing (GO:0006342)2.68709816
122glycerol metabolic process (GO:0006071)2.68361176
123regulation of establishment of cell polarity (GO:2000114)2.67855752
124serotonin receptor signaling pathway (GO:0007210)2.67742174
125positive regulation of Rab GTPase activity (GO:0032851)2.64884424
126regulation of Rab GTPase activity (GO:0032313)2.64884424
127thyroid hormone metabolic process (GO:0042403)2.64321208
128carnitine transmembrane transport (GO:1902603)2.63809230
129cilium morphogenesis (GO:0060271)2.63385451
130benzene-containing compound metabolic process (GO:0042537)2.62818185
131sulfation (GO:0051923)2.62293958
132replication fork processing (GO:0031297)2.61112961
133regulation of collateral sprouting (GO:0048670)2.60366276
134interferon-gamma secretion (GO:0072643)2.59994455
135reciprocal meiotic recombination (GO:0007131)2.58031050
136reciprocal DNA recombination (GO:0035825)2.58031050
137regulation of meiosis I (GO:0060631)2.58013371
138phosphatidylethanolamine biosynthetic process (GO:0006646)2.57755962
139lactate metabolic process (GO:0006089)2.57551168
140polyamine biosynthetic process (GO:0006596)2.55233284
141intraciliary transport (GO:0042073)2.53725411
142axoneme assembly (GO:0035082)2.48038674
143regulation of cilium assembly (GO:1902017)2.46605109
144UTP biosynthetic process (GO:0006228)2.45781013
145gene silencing by RNA (GO:0031047)2.43625237
146peptidyl-threonine dephosphorylation (GO:0035970)2.36321788
147gene silencing (GO:0016458)2.32872581
148cell wall macromolecule metabolic process (GO:0044036)15.4393359
149cell wall macromolecule catabolic process (GO:0016998)15.4393359
150fusion of sperm to egg plasma membrane (GO:0007342)14.3025122
151sperm motility (GO:0030317)13.5938456
152acrosome assembly (GO:0001675)11.9602486
153multicellular organism reproduction (GO:0032504)11.7233842
154sperm-egg recognition (GO:0035036)11.7052870
155acrosome reaction (GO:0007340)11.6167012
156plasma membrane fusion (GO:0045026)10.9133536
157cell-cell recognition (GO:0009988)10.4966582
158binding of sperm to zona pellucida (GO:0007339)10.4300972
159reproduction (GO:0000003)10.2297227
160epithelial cilium movement (GO:0003351)10.0128713

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.86817325
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.04585226
3EZH2_22144423_ChIP-Seq_EOC_Human3.70527915
4GBX2_23144817_ChIP-Seq_PC3_Human3.59008812
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.26898808
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.24581459
7IGF1R_20145208_ChIP-Seq_DFB_Human2.86600325
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.79820695
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.66973080
10SALL1_21062744_ChIP-ChIP_HESCs_Human2.46782837
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.45850210
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.34491515
13VDR_22108803_ChIP-Seq_LS180_Human2.29928865
14P300_19829295_ChIP-Seq_ESCs_Human2.29276786
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.28721745
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.25312557
17CTBP1_25329375_ChIP-Seq_LNCAP_Human2.19255620
18ER_23166858_ChIP-Seq_MCF-7_Human2.18037014
19CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.10468097
20AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.09382028
21PCGF2_27294783_Chip-Seq_ESCs_Mouse2.08899031
22KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse2.03464597
23EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.01493622
24ZNF274_21170338_ChIP-Seq_K562_Hela2.00663330
25GATA1_26923725_Chip-Seq_HPCs_Mouse1.94083042
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.93804431
27UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.92470261
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.92111405
29SMAD4_21799915_ChIP-Seq_A2780_Human1.91188641
30STAT3_23295773_ChIP-Seq_U87_Human1.90998033
31EWS_26573619_Chip-Seq_HEK293_Human1.90277672
32TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.85540463
33KAP1_22055183_ChIP-Seq_ESCs_Mouse1.83966453
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.83825363
35STAT1_17558387_ChIP-Seq_HELA_Human1.78306761
36MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.77488553
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77336751
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.75945348
39ELK4_26923725_Chip-Seq_MESODERM_Mouse1.71457738
40KDM2B_26808549_Chip-Seq_REH_Human1.71404899
41AR_25329375_ChIP-Seq_VCAP_Human1.70620342
42TCF4_23295773_ChIP-Seq_U87_Human1.70375945
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.69073823
44TAL1_26923725_Chip-Seq_HPCs_Mouse1.64633872
45GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.63006660
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.60476051
47BCAT_22108803_ChIP-Seq_LS180_Human1.60423398
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60129385
49WDR5_24793694_ChIP-Seq_LNCAP_Human1.56840221
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.54657528
51FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54019882
52SOX2_22085726_ChIP-Seq_NPCs_Mouse1.52444005
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.52406400
54GATA3_21867929_ChIP-Seq_CD8_Mouse1.51803901
55NR3C1_21868756_ChIP-Seq_MCF10A_Human1.51237653
56NFE2_27457419_Chip-Seq_LIVER_Mouse1.48435004
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47019961
58ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.46738825
59ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46412797
60KLF5_20875108_ChIP-Seq_MESCs_Mouse1.46385505
61PCGF2_27294783_Chip-Seq_NPCs_Mouse1.45537635
62SUZ12_27294783_Chip-Seq_NPCs_Mouse1.43784537
63RUNX2_22187159_ChIP-Seq_PCA_Human1.42011216
64TCF4_22108803_ChIP-Seq_LS180_Human1.41416241
65SMAD4_21741376_ChIP-Seq_EPCs_Human1.41283640
66CTBP2_25329375_ChIP-Seq_LNCAP_Human1.41170784
67GATA3_21867929_ChIP-Seq_TH1_Mouse1.38414293
68CBP_20019798_ChIP-Seq_JUKART_Human1.37329306
69IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37329306
70AR_21572438_ChIP-Seq_LNCaP_Human1.36444158
71FLI1_21867929_ChIP-Seq_TH2_Mouse1.35861260
72CDX2_22108803_ChIP-Seq_LS180_Human1.33373555
73LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.33336451
74TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33270355
75SOX2_19829295_ChIP-Seq_ESCs_Human1.32546263
76NANOG_19829295_ChIP-Seq_ESCs_Human1.32546263
77PRDM14_20953172_ChIP-Seq_ESCs_Human1.32295554
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.31997967
79REST_21632747_ChIP-Seq_MESCs_Mouse1.30997573
80FOXA1_21572438_ChIP-Seq_LNCaP_Human1.29922637
81CRX_20693478_ChIP-Seq_RETINA_Mouse1.28002231
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27506964
83OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26902922
84SMAD_19615063_ChIP-ChIP_OVARY_Human1.25859966
85HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.25856167
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.24795887
87GF1_26923725_Chip-Seq_HPCs_Mouse1.24458671
88PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.23727433
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23391655
90FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.23266286
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22412387
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.22412387
93MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22356326
94CMYC_18555785_Chip-Seq_ESCs_Mouse1.22345203
95P53_21459846_ChIP-Seq_SAOS-2_Human1.22344729
96OCT4_18555785_Chip-Seq_ESCs_Mouse1.21704564
97CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20903351
98CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.20260164
99P53_22387025_ChIP-Seq_ESCs_Mouse1.19292290
100SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.19221557
101EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.18321966
102TAF15_26573619_Chip-Seq_HEK293_Human1.18022864
103CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17195702
104TP53_22573176_ChIP-Seq_HFKS_Human1.16703949
105FOXA1_27270436_Chip-Seq_PROSTATE_Human1.15720537
106FOXA1_25329375_ChIP-Seq_VCAP_Human1.15720537
107TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14616843
108ARNT_22903824_ChIP-Seq_MCF-7_Human1.14465957
109RUNX1_26923725_Chip-Seq_HPCs_Mouse1.13465980
110P300_18555785_Chip-Seq_ESCs_Mouse1.13411572
111DROSHA_22980978_ChIP-Seq_HELA_Human1.12383761
112SPI1_26923725_Chip-Seq_HPCs_Mouse1.11014034
113EZH2_27294783_Chip-Seq_NPCs_Mouse1.10255696
114KLF4_18555785_Chip-Seq_ESCs_Mouse1.08632434
115TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08566977
116NFIB_24661679_ChIP-Seq_LUNG_Mouse1.07536577
117SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.07263566
118EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07052657
119SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05888498
120RAD21_21589869_ChIP-Seq_MESCs_Mouse1.05453851
121OCT4_21477851_ChIP-Seq_ESCs_Mouse1.04802560
122ESRRB_18555785_Chip-Seq_ESCs_Mouse1.04659629
123ESET_19884257_ChIP-Seq_ESCs_Mouse1.04584926
124CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04244280
125SOX2_21211035_ChIP-Seq_LN229_Gbm1.03728623
126SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03672156
127SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.03351569
128TP53_18474530_ChIP-ChIP_U2OS_Human1.03109923
129SOX2_18555785_Chip-Seq_ESCs_Mouse1.03073926
130AUTS2_25519132_ChIP-Seq_293T-REX_Human1.03031758
131RNF2_27304074_Chip-Seq_NSC_Mouse1.02845846
132FUS_26573619_Chip-Seq_HEK293_Human1.02665212
133IRF1_19129219_ChIP-ChIP_H3396_Human1.02444784
134PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02415366
135SOX9_26525672_Chip-Seq_HEART_Mouse1.01619315
136FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.01304605
137ETV2_25802403_ChIP-Seq_MESCs_Mouse1.01093889
138NFYB_21822215_ChIP-Seq_K562_Human1.00257837
139GF1B_26923725_Chip-Seq_HPCs_Mouse0.98914233
140KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.98862352
141GATA3_21878914_ChIP-Seq_MCF-7_Human0.98609658
142TBL1_22424771_ChIP-Seq_293T_Human0.98538018
143STAT3_18555785_Chip-Seq_ESCs_Mouse0.98170624
144SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97234200
145EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.96419545
146GATA1_19941827_ChIP-Seq_MEL86_Mouse0.96147560
147PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95551525
148PU1_27457419_Chip-Seq_LIVER_Mouse0.94279836
149RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93743614
150CTCF_18555785_Chip-Seq_ESCs_Mouse0.93638133
151ERG_20517297_ChIP-Seq_VCAP_Human0.93618766
152CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93109977
153STAT3_18555785_ChIP-Seq_MESCs_Mouse0.92820503
154E2F1_18555785_Chip-Seq_ESCs_Mouse0.92715523

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.14878107
2MP0001929_abnormal_gametogenesis5.68535769
3MP0008877_abnormal_DNA_methylation4.31519293
4MP0002210_abnormal_sex_determination3.48326859
5MP0002161_abnormal_fertility/fecundity3.39096652
6MP0001145_abnormal_male_reproductive2.94317169
7MP0005670_abnormal_white_adipose2.79117642
8MP0002653_abnormal_ependyma_morphology2.65680162
9MP0000653_abnormal_sex_gland2.61634908
10MP0003195_calcinosis2.25521057
11MP0001501_abnormal_sleep_pattern2.24112698
12MP0005410_abnormal_fertilization16.2696998
13MP0001486_abnormal_startle_reflex1.96978189
14MP0002138_abnormal_hepatobiliary_system1.96358194
15MP0003718_maternal_effect1.88973619
16MP0006276_abnormal_autonomic_nervous1.79736127
17MP0005174_abnormal_tail_pigmentation1.79336210
18MP0009745_abnormal_behavioral_response1.73317743
19MP0000427_abnormal_hair_cycle1.73161362
20MP0000372_irregular_coat_pigmentation1.73146783
21MP0001986_abnormal_taste_sensitivity1.73117034
22MP0003880_abnormal_central_pattern1.71712798
23MP0002735_abnormal_chemical_nociception1.70604250
24MP0005310_abnormal_salivary_gland1.69710207
25MP0005646_abnormal_pituitary_gland1.65319580
26MP0004233_abnormal_muscle_weight1.63120052
27MP0005645_abnormal_hypothalamus_physiol1.60603204
28MP0001485_abnormal_pinna_reflex1.60061596
29MP0003136_yellow_coat_color1.45615820
30MP0008872_abnormal_physiological_respon1.43585876
31MP0002254_reproductive_system_inflammat1.41950392
32MP0003646_muscle_fatigue1.41535062
33MP0005623_abnormal_meninges_morphology1.41027183
34MP0004043_abnormal_pH_regulation1.39076173
35MP0006292_abnormal_olfactory_placode1.38994567
36MP0002837_dystrophic_cardiac_calcinosis1.38474191
37MP0002160_abnormal_reproductive_system1.38318108
38MP0002876_abnormal_thyroid_physiology1.37810457
39MP0002272_abnormal_nervous_system1.33859758
40MP0004147_increased_porphyrin_level1.32186114
41MP0002067_abnormal_sensory_capabilities1.27572183
42MP0002938_white_spotting1.25165079
43MP0001765_abnormal_ion_homeostasis1.21190565
44MP0002572_abnormal_emotion/affect_behav1.20905599
45MP0002282_abnormal_trachea_morphology1.19259625
46MP0001970_abnormal_pain_threshold1.18697171
47MP0005379_endocrine/exocrine_gland_phen1.16357146
48MP0010386_abnormal_urinary_bladder1.13832009
49MP0000383_abnormal_hair_follicle1.13556456
50MP0000015_abnormal_ear_pigmentation1.12605494
51MP0002234_abnormal_pharynx_morphology1.12309462
52MP0008058_abnormal_DNA_repair1.11058689
53MP0008875_abnormal_xenobiotic_pharmacok1.09876188
54MP0003252_abnormal_bile_duct1.09514054
55MP0002102_abnormal_ear_morphology1.08890865
56MP0002095_abnormal_skin_pigmentation1.08851687
57MP0002064_seizures1.08017670
58MP0005395_other_phenotype1.05386249
59MP0001529_abnormal_vocalization1.05142786
60MP0002557_abnormal_social/conspecific_i1.03870435
61MP0003183_abnormal_peptide_metabolism1.03390127
62MP0001984_abnormal_olfaction1.02394686
63MP0005647_abnormal_sex_gland1.01720472
64MP0000631_abnormal_neuroendocrine_gland1.00753464
65MP0002733_abnormal_thermal_nociception0.98159885
66MP0005423_abnormal_somatic_nervous0.97136948
67MP0004924_abnormal_behavior0.97038395
68MP0005386_behavior/neurological_phenoty0.97038395
69MP0001963_abnormal_hearing_physiology0.94412760
70MP0009046_muscle_twitch0.94291074
71MP0004142_abnormal_muscle_tone0.91043863
72MP0000230_abnormal_systemic_arterial0.90509743
73MP0006054_spinal_hemorrhage0.86016924
74MP0003635_abnormal_synaptic_transmissio0.84413738
75MP0004085_abnormal_heartbeat0.84379503
76MP0002734_abnormal_mechanical_nocicepti0.84132393
77MP0005085_abnormal_gallbladder_physiolo0.83545266
78MP0004215_abnormal_myocardial_fiber0.80049638
79MP0005084_abnormal_gallbladder_morpholo0.78555722
80MP0000371_diluted_coat_color0.77852771
81MP0005167_abnormal_blood-brain_barrier0.77594521
82MP0008789_abnormal_olfactory_epithelium0.77479035
83MP0002168_other_aberrant_phenotype0.76506509
84MP0008995_early_reproductive_senescence0.73813382
85MP0005266_abnormal_metabolism0.73609572
86MP0005389_reproductive_system_phenotype0.70575286
87MP0010094_abnormal_chromosome_stability0.66647903
88MP0003699_abnormal_female_reproductive0.63355491
89MP0005636_abnormal_mineral_homeostasis0.60410276
90MP0003115_abnormal_respiratory_system0.59092579
91MP0002736_abnormal_nociception_after0.54187728
92MP0002928_abnormal_bile_duct0.52066991
93MP0005377_hearing/vestibular/ear_phenot0.51964211
94MP0003878_abnormal_ear_physiology0.51964211
95MP0003011_delayed_dark_adaptation0.51961943
96MP0001324_abnormal_eye_pigmentation0.50383391
97MP0002269_muscular_atrophy0.50035946
98MP0005666_abnormal_adipose_tissue0.50028067
99MP0001119_abnormal_female_reproductive0.47844037
100MP0005551_abnormal_eye_electrophysiolog0.47008513
101MP0004036_abnormal_muscle_relaxation0.44568816
102MP0003111_abnormal_nucleus_morphology0.43633200
103MP0001293_anophthalmia0.41129155
104MP0000358_abnormal_cell_content/0.40942139
105MP0001764_abnormal_homeostasis0.39889409
106MP0009115_abnormal_fat_cell0.39219383
107MP0005253_abnormal_eye_physiology0.37353508
108MP0003950_abnormal_plasma_membrane0.35931335
109MP0003329_amyloid_beta_deposits0.35824678
110MP0002971_abnormal_brown_adipose0.35506861
111MP0006036_abnormal_mitochondrial_physio0.32702885
112MP0001968_abnormal_touch/_nociception0.31484054
113MP0004133_heterotaxia0.29765428
114MP0008057_abnormal_DNA_replication0.29698788
115MP0003633_abnormal_nervous_system0.28436887
116MP0003861_abnormal_nervous_system0.28172735
117MP0002139_abnormal_hepatobiliary_system0.27276923
118MP0005391_vision/eye_phenotype0.26616185
119MP0001849_ear_inflammation0.25809676
120MP0003787_abnormal_imprinting0.25570741
121MP0001545_abnormal_hematopoietic_system0.25293933
122MP0005397_hematopoietic_system_phenotyp0.25293933
123MP0004145_abnormal_muscle_electrophysio0.24545897
124MP0004019_abnormal_vitamin_homeostasis0.24345231
125MP0000462_abnormal_digestive_system0.23856991
126MP0005451_abnormal_body_composition0.23658898
127MP0003631_nervous_system_phenotype0.23632290
128MP0002152_abnormal_brain_morphology0.23323132
129MP0010307_abnormal_tumor_latency0.23115966
130MP0003879_abnormal_hair_cell0.22319303
131MP0000534_abnormal_ureter_morphology0.22268807
132MP0001730_embryonic_growth_arrest0.22128158
133MP0003786_premature_aging0.21395555
134MP0004811_abnormal_neuron_physiology0.21297561
135MP0004270_analgesia0.20969025
136MP0002169_no_abnormal_phenotype0.20165179
137MP0002873_normal_phenotype0.19937112
138MP0006035_abnormal_mitochondrial_morpho0.19822662
139MP0008569_lethality_at_weaning0.19456758
140MP0000569_abnormal_digit_pigmentation0.19073939
141MP0002084_abnormal_developmental_patter0.18434394
142MP0002693_abnormal_pancreas_physiology0.18291770
143MP0003942_abnormal_urinary_system0.17332608
144MP0008961_abnormal_basal_metabolism0.17230288
145MP0006072_abnormal_retinal_apoptosis0.17172580
146MP0002752_abnormal_somatic_nervous0.17106218
147MP0009697_abnormal_copulation0.16357036
148MP0000313_abnormal_cell_death0.16309204
149MP0005195_abnormal_posterior_eye0.15897507
150MP0008007_abnormal_cellular_replicative0.15625744
151MP0004742_abnormal_vestibular_system0.15532521
152MP0003890_abnormal_embryonic-extraembry0.14071024
153MP0000432_abnormal_head_morphology0.13879901
154MP0009250_abnormal_appendicular_skeleto0.13684800
155MP0000001_mammalian_phenotype0.13244980
156MP0000604_amyloidosis0.13179985
157MP0001697_abnormal_embryo_size0.13025461
158MP0005380_embryogenesis_phenotype0.12524090
159MP0001672_abnormal_embryogenesis/_devel0.12524090
160MP0003948_abnormal_gas_homeostasis0.12486913
161MP0002229_neurodegeneration0.12430406
162MP0005535_abnormal_body_temperature0.12117951

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.43042573
2Abnormal respiratory motile cilium morphology (HP:0005938)9.39460230
3Abnormal respiratory epithelium morphology (HP:0012253)9.39460230
4Abnormal ciliary motility (HP:0012262)7.67933226
5Chronic bronchitis (HP:0004469)7.51458258
6Rhinitis (HP:0012384)7.42864836
7Infertility (HP:0000789)6.55657049
8Nasal polyposis (HP:0100582)6.26392073
9Abnormality of the nasal mucosa (HP:0000433)5.12961429
10Male infertility (HP:0003251)4.65311128
11Pancreatic cysts (HP:0001737)4.49534819
12Bronchitis (HP:0012387)4.48796594
13Attenuation of retinal blood vessels (HP:0007843)4.44907545
14Bronchiectasis (HP:0002110)4.38601165
15Hyperventilation (HP:0002883)3.96663873
16Nephronophthisis (HP:0000090)3.89128410
17Bony spicule pigmentary retinopathy (HP:0007737)3.72999319
18Recurrent sinusitis (HP:0011108)3.51155758
19Abnormal spermatogenesis (HP:0008669)3.47763944
20Congenital stationary night blindness (HP:0007642)3.42237881
21Severe visual impairment (HP:0001141)3.41865699
22Gaze-evoked nystagmus (HP:0000640)3.29062601
23Progressive cerebellar ataxia (HP:0002073)3.24185366
24Congenital sensorineural hearing impairment (HP:0008527)3.20574837
25Recurrent otitis media (HP:0000403)3.17364213
26Medial flaring of the eyebrow (HP:0010747)3.07324765
27Abnormal rod and cone electroretinograms (HP:0008323)3.06251767
28Genetic anticipation (HP:0003743)2.97768717
29Abnormality of the renal medulla (HP:0100957)2.96083310
30Intestinal atresia (HP:0011100)2.91792943
31Abolished electroretinogram (ERG) (HP:0000550)2.90678495
32Abnormality of macular pigmentation (HP:0008002)2.87844315
33Tubulointerstitial nephritis (HP:0001970)2.81359640
34Absent speech (HP:0001344)2.60947264
35Febrile seizures (HP:0002373)2.60224902
36Abnormality of midbrain morphology (HP:0002418)2.58319436
37Molar tooth sign on MRI (HP:0002419)2.58319436
38Aplasia/Hypoplasia of the tibia (HP:0005772)2.56798193
39Recurrent bronchitis (HP:0002837)2.47022152
40Tubular atrophy (HP:0000092)2.39031031
41Impulsivity (HP:0100710)2.37863085
42Type II lissencephaly (HP:0007260)2.33667364
43Azoospermia (HP:0000027)2.30779963
44Increased corneal curvature (HP:0100692)2.30356696
45Keratoconus (HP:0000563)2.30356696
46Inability to walk (HP:0002540)2.26265025
47Pendular nystagmus (HP:0012043)2.25716747
48Central scotoma (HP:0000603)2.24298834
49Fair hair (HP:0002286)2.24019229
50Tubulointerstitial abnormality (HP:0001969)2.22264658
51Sclerocornea (HP:0000647)2.16189091
52Congenital primary aphakia (HP:0007707)2.14884831
53Gait imbalance (HP:0002141)2.14836683
54Renal cortical cysts (HP:0000803)2.12195071
55Volvulus (HP:0002580)2.10835238
56Focal seizures (HP:0007359)2.08352028
57Protruding tongue (HP:0010808)2.08298763
58Polyuria (HP:0000103)2.08281986
59Dialeptic seizures (HP:0011146)2.08050864
60Cholecystitis (HP:0001082)2.05213110
61Abnormal gallbladder physiology (HP:0012438)2.05213110
62Abnormality of alanine metabolism (HP:0010916)2.04040131
63Hyperalaninemia (HP:0003348)2.04040131
64Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.04040131
65Anencephaly (HP:0002323)2.03488488
66Progressive inability to walk (HP:0002505)2.00193546
67Dynein arm defect of respiratory motile cilia (HP:0012255)13.5620097
68Absent/shortened dynein arms (HP:0200106)13.5620097
69Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1872373
70Gastrointestinal atresia (HP:0002589)1.97904284
71Thyroiditis (HP:0100646)1.94800833
72Small hand (HP:0200055)1.94102000
73Aplasia/Hypoplasia of the uvula (HP:0010293)1.93755279
74Hypoplastic ischia (HP:0003175)1.93622580
75Absent rod-and cone-mediated responses on ERG (HP:0007688)1.93051581
76Astigmatism (HP:0000483)1.92240829
77Occipital encephalocele (HP:0002085)1.91172252
78Furrowed tongue (HP:0000221)1.88011975
79Scotoma (HP:0000575)1.86423057
80Male pseudohermaphroditism (HP:0000037)1.85698403
81Nephrogenic diabetes insipidus (HP:0009806)1.85318180
82Decreased circulating renin level (HP:0003351)1.84593413
83Amelogenesis imperfecta (HP:0000705)1.84421969
84Gonadotropin excess (HP:0000837)1.84084644
85Retinitis pigmentosa (HP:0000510)1.83835684
86Portal hypertension (HP:0001409)1.83175035
87Focal motor seizures (HP:0011153)1.82681628
88Sloping forehead (HP:0000340)1.81391856
89Abnormal urine output (HP:0012590)1.80707725
90Aplasia/Hypoplasia of the lens (HP:0008063)1.79849112
91Widely spaced teeth (HP:0000687)1.79817444
92Dyschromatopsia (HP:0007641)1.79458758
93Retinal dysplasia (HP:0007973)1.78974439
94Hyperkalemia (HP:0002153)1.76842120
95Clumsiness (HP:0002312)1.76495044
96Abnormality of the hepatic vasculature (HP:0006707)1.76042549
97Abnormality of the ischium (HP:0003174)1.74807193
98Hypoproteinemia (HP:0003075)1.74118330
99Decreased central vision (HP:0007663)1.72748059
100Postaxial foot polydactyly (HP:0001830)1.72679493
101Stage 5 chronic kidney disease (HP:0003774)1.67223042
102Chronic sinusitis (HP:0011109)1.67199232
103Poor coordination (HP:0002370)1.64981367
104Vaginal atresia (HP:0000148)1.64913306
105Tubulointerstitial fibrosis (HP:0005576)1.64183591
106Asymmetric septal hypertrophy (HP:0001670)1.63549578
107Genital tract atresia (HP:0001827)1.62841888
108Heterotopia (HP:0002282)1.62737587
109Congenital hepatic fibrosis (HP:0002612)1.61103647
110Spastic tetraparesis (HP:0001285)1.58648734
111Abnormal biliary tract physiology (HP:0012439)1.58260267
112Bile duct proliferation (HP:0001408)1.58260267
113Postaxial hand polydactyly (HP:0001162)1.54867565
114Bundle branch block (HP:0011710)1.54344549
115Abnormality of the renal cortex (HP:0011035)1.54058779
116Abnormality of the dental root (HP:0006486)1.53707011
117Taurodontia (HP:0000679)1.53707011
118Abnormality of permanent molar morphology (HP:0011071)1.53707011
119Tongue fasciculations (HP:0001308)1.52548578
120Abnormality of renal excretion (HP:0011036)1.50774881
121Choroideremia (HP:0001139)1.48953434
122Congenital malformation of the right heart (HP:0011723)1.48069921
123Double outlet right ventricle (HP:0001719)1.48069921
124Abnormal drinking behavior (HP:0030082)1.45744720
125Polydipsia (HP:0001959)1.45744720
126Pancreatic fibrosis (HP:0100732)1.45692161
127Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.44919622
128Fatigable weakness (HP:0003473)1.44784390
129Abnormality of the neuromuscular junction (HP:0003398)1.44784390
130Abnormality of saccadic eye movements (HP:0000570)1.43808238
131Easy fatigability (HP:0003388)1.42911207
132Abnormality of molar morphology (HP:0011070)1.42867989
133Abnormality of molar (HP:0011077)1.42867989
134Oculomotor apraxia (HP:0000657)1.42337410
135Cystic liver disease (HP:0006706)1.41669712
136Abnormality of the dental pulp (HP:0006479)1.41368240
137Optic nerve hypoplasia (HP:0000609)1.41318979
138Type 2 muscle fiber atrophy (HP:0003554)1.40962595
139Muscle fibrillation (HP:0010546)1.39353632
140Short ribs (HP:0000773)1.38665082
141Facial cleft (HP:0002006)1.35063127
142Supernumerary spleens (HP:0009799)1.33642360
143Hemorrhage of the eye (HP:0011885)1.33246140
144Renal dysplasia (HP:0000110)1.32773089
145Constricted visual fields (HP:0001133)1.31290933
146Hypoplasia of the capital femoral epiphysis (HP:0003090)1.31278279
147Sensory axonal neuropathy (HP:0003390)1.29560528
148Fibular hypoplasia (HP:0003038)1.29507398
149Aplasia/Hypoplasia of the tongue (HP:0010295)1.29388977
150Abnormality of ocular smooth pursuit (HP:0000617)1.29296529
151Impaired smooth pursuit (HP:0007772)1.27381903
152Decreased electroretinogram (ERG) amplitude (HP:0000654)1.24542445
153True hermaphroditism (HP:0010459)1.24294823
154Bell-shaped thorax (HP:0001591)1.23293956
155Abnormality of dentin (HP:0010299)1.23031955
156Cerebellar dysplasia (HP:0007033)1.22608690
157Microglossia (HP:0000171)1.21987931
158Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.19700712
159Decreased muscle mass (HP:0003199)1.16680519
160Chronic hepatic failure (HP:0100626)1.16300331
161Vascular calcification (HP:0004934)1.15285664

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK39.11521004
2PDK49.11521004
3FRK8.17285782
4PDK25.90158583
5TESK14.87025341
6PRKD34.11807416
7ICK3.66633110
8MAP4K23.25156515
9ACVR1B2.54926630
10NUAK12.41825901
11INSRR2.40631876
12BMPR1B2.33235592
13ADRBK22.28040874
14TAOK32.01138032
15PTK2B1.90365003
16WNK41.84884396
17STK391.81493873
18CASK1.76535471
19ZAK1.73127447
20MAPK131.72529941
21OXSR11.71531839
22PIK3CG1.65946774
23STK381.63724696
24PLK21.60315845
25PNCK1.56683551
26GRK11.53840712
27MKNK21.42041199
28DYRK1B1.38903155
29NEK21.34068603
30TRIM281.31007955
31NTRK31.21252323
32PDK11.19500297
33EIF2AK31.16179024
34FER1.11325223
35ERBB31.09554610
36IRAK11.01305844
37TXK0.99058785
38AKT30.97501722
39BCR0.95598706
40TEC0.95595650
41ADRBK10.90224350
42PRKCE0.90106562
43PLK40.89793174
44BRD40.88690933
45STK38L0.86723106
46PAK30.84127008
47TYRO30.82320455
48DYRK30.82053423
49LMTK20.78996053
50CHEK20.77936451
51TNK20.74455615
52TNIK0.72074301
53MARK10.70914507
54MKNK10.70886665
55DAPK20.69196147
56CSNK1G10.67355589
57TTK0.65995849
58TIE10.65381003
59PDPK10.64960221
60MAP2K60.64521562
61EPHA40.64296971
62CSNK1G20.63464622
63STK30.63294978
64MUSK0.60098149
65WNK10.59877545
66CSNK1A1L0.59626456
67MAP3K70.57871646
68CCNB10.56904880
69TRPM70.56135493
70MAPK150.54975852
71NLK0.53936571
72RIPK40.53351643
73EEF2K0.52763004
74CSNK1G30.51518303
75TGFBR10.51500513
76IRAK20.50825934
77PASK0.50294520
78PRKAA20.50244179
79TESK20.47732960
80IKBKB0.45777218
81MST40.45010813
82CHEK10.44093564
83KIT0.43263058
84FLT30.42477010
85PIK3CA0.40916752
86DYRK20.40278650
87NTRK20.38186809
88CDK190.37908096
89CAMK1G0.37176579
90CDK120.36389908
91SGK20.35785579
92PAK10.34891629
93LATS10.33794714
94MARK20.33655828
95PRKACA0.32955314
96GRK70.32521196
97CDC70.31910585
98BRSK20.31321831
99PINK10.31207738
100PRKACB0.31036980
101BRAF0.30951638
102CAMKK20.30255167
103CSNK1A10.30131277
104GRK50.29644752
105OBSCN0.29365438
106ATM0.29119342
107CAMK10.28786828
108DDR20.27706605
109PRKCG0.27413915
110PLK30.26925865
111CAMK40.25692311
112ITK0.25553714
113NEK60.24603188
114CHUK0.23805377
115MAPKAPK50.23265252
116ATR0.21149176
117WEE10.20579149
118PLK10.19421812
119PRKAA10.17548579
120YES10.17027741
121MAP3K100.16775557
122PKN10.16417181
123PAK20.15585220
124MTOR0.14848135
125CDK150.14412421
126MAP3K60.14051746
127PRKCZ0.13609145
128MAP3K40.12814212
129PRKG20.11624292
130BRSK10.11518802
131CDK180.11502318
132CDK11A0.10838330
133PRKCQ0.10696053
134MARK30.09985288
135MAP2K70.09900686
136CAMKK10.09517243
137PRKG10.08695729
138GSK3B0.07016524
139CAMK2A0.06852347
140RPS6KB10.06567198
141CDK140.06011550
142CSNK2A10.05944389
143MAP3K50.05790453
144CSNK1D0.05517178
145PDGFRB0.05017782
146STK100.04808516
147CDK20.04398507
148RPS6KA10.03272505
149CDK10.03164690
150CDK30.02906894
151CDK60.02823808
152CSNK2A20.02769165
153STK110.02640428
154LATS20.01702287
155EGFR0.01486046
156PAK40.01361598
157MAPK80.00772378
158PRKACG0.00473468
159WNK30.00219628
160PIM1-0.0233728
161RIPK1-0.0195083
162ERBB4-0.0108013
163CDK4-0.0059827
164PRKCB-0.0056911
165AURKA-0.0037447
166PRKCA-0.0031839

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.49958356
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.49592487
3Vitamin B6 metabolism_Homo sapiens_hsa007503.77218196
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.60311217
5Pyruvate metabolism_Homo sapiens_hsa006203.44774824
6Butanoate metabolism_Homo sapiens_hsa006503.19434029
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.11363910
8Linoleic acid metabolism_Homo sapiens_hsa005913.04153607
9Basal transcription factors_Homo sapiens_hsa030222.82082187
10Phototransduction_Homo sapiens_hsa047442.72564350
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.69900096
12Propanoate metabolism_Homo sapiens_hsa006402.67810982
13Glucagon signaling pathway_Homo sapiens_hsa049222.53981922
14Olfactory transduction_Homo sapiens_hsa047402.25480354
15Nicotine addiction_Homo sapiens_hsa050332.18771995
16Carbohydrate digestion and absorption_Homo sapiens_hsa049732.16163202
17Glycosaminoglycan degradation_Homo sapiens_hsa005312.13043460
18Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.11658606
19Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.10714546
20Homologous recombination_Homo sapiens_hsa034402.09504218
21Tryptophan metabolism_Homo sapiens_hsa003802.06232658
22Primary bile acid biosynthesis_Homo sapiens_hsa001202.01015161
23Selenocompound metabolism_Homo sapiens_hsa004501.98065613
24Nitrogen metabolism_Homo sapiens_hsa009101.94005395
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.93475782
26Glycerolipid metabolism_Homo sapiens_hsa005611.89871451
27Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.88628783
28Oocyte meiosis_Homo sapiens_hsa041141.84102469
29Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.81950046
30Pentose phosphate pathway_Homo sapiens_hsa000301.80665062
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.79189015
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.78674354
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74024832
34Non-homologous end-joining_Homo sapiens_hsa034501.73069674
35PPAR signaling pathway_Homo sapiens_hsa033201.72023446
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.68951438
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.68623193
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.62325782
39Mineral absorption_Homo sapiens_hsa049781.54658912
40Morphine addiction_Homo sapiens_hsa050321.49453799
41Ether lipid metabolism_Homo sapiens_hsa005651.48014037
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.47727293
43Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.43153819
44Fanconi anemia pathway_Homo sapiens_hsa034601.40032400
45Dorso-ventral axis formation_Homo sapiens_hsa043201.38066859
46Amphetamine addiction_Homo sapiens_hsa050311.37766836
47Fructose and mannose metabolism_Homo sapiens_hsa000511.36405268
48Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.34481477
49Carbon metabolism_Homo sapiens_hsa012001.33017737
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.28939667
51Serotonergic synapse_Homo sapiens_hsa047261.24034818
52Cysteine and methionine metabolism_Homo sapiens_hsa002701.23398175
53Fat digestion and absorption_Homo sapiens_hsa049751.21367357
54Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.20609302
55Caffeine metabolism_Homo sapiens_hsa002321.19465615
56Maturity onset diabetes of the young_Homo sapiens_hsa049501.19070375
57Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.18538267
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.17729401
59Cardiac muscle contraction_Homo sapiens_hsa042601.16991617
60Fatty acid metabolism_Homo sapiens_hsa012121.16170994
61Retinol metabolism_Homo sapiens_hsa008301.13701478
62Purine metabolism_Homo sapiens_hsa002301.11512571
63Fatty acid degradation_Homo sapiens_hsa000711.11064813
64GABAergic synapse_Homo sapiens_hsa047271.09572138
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.04879307
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.04232901
67Huntingtons disease_Homo sapiens_hsa050161.02502955
68Collecting duct acid secretion_Homo sapiens_hsa049660.99333778
69Glutathione metabolism_Homo sapiens_hsa004800.97909641
70Antigen processing and presentation_Homo sapiens_hsa046120.97765653
71Renin secretion_Homo sapiens_hsa049240.97549410
72mRNA surveillance pathway_Homo sapiens_hsa030150.97190241
73Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94918946
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.93047179
75Peroxisome_Homo sapiens_hsa041460.92942704
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91831437
77Biosynthesis of amino acids_Homo sapiens_hsa012300.91277166
78beta-Alanine metabolism_Homo sapiens_hsa004100.90795525
79Histidine metabolism_Homo sapiens_hsa003400.88157568
80RNA transport_Homo sapiens_hsa030130.82722433
81Insulin secretion_Homo sapiens_hsa049110.82652073
82Chemical carcinogenesis_Homo sapiens_hsa052040.81342560
83Hedgehog signaling pathway_Homo sapiens_hsa043400.79643141
84Sphingolipid metabolism_Homo sapiens_hsa006000.79431534
85Lysine degradation_Homo sapiens_hsa003100.76400866
86Arachidonic acid metabolism_Homo sapiens_hsa005900.76307428
87Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75120576
88Bile secretion_Homo sapiens_hsa049760.73322811
89Estrogen signaling pathway_Homo sapiens_hsa049150.72542990
90Thyroid hormone synthesis_Homo sapiens_hsa049180.71948309
91Protein export_Homo sapiens_hsa030600.71328298
92Renin-angiotensin system_Homo sapiens_hsa046140.70102184
93RNA polymerase_Homo sapiens_hsa030200.69674512
94Regulation of autophagy_Homo sapiens_hsa041400.69620419
95One carbon pool by folate_Homo sapiens_hsa006700.66648603
96Inositol phosphate metabolism_Homo sapiens_hsa005620.66247833
97Ovarian steroidogenesis_Homo sapiens_hsa049130.64106791
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63408163
99Long-term potentiation_Homo sapiens_hsa047200.62545307
100Adipocytokine signaling pathway_Homo sapiens_hsa049200.60379445
101Circadian rhythm_Homo sapiens_hsa047100.59617305
102Calcium signaling pathway_Homo sapiens_hsa040200.57523323
103Synaptic vesicle cycle_Homo sapiens_hsa047210.56637812
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55584029
105Long-term depression_Homo sapiens_hsa047300.54236806
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54228653
107Protein digestion and absorption_Homo sapiens_hsa049740.52904674
108Cholinergic synapse_Homo sapiens_hsa047250.51979940
109Pancreatic secretion_Homo sapiens_hsa049720.51223098
110Central carbon metabolism in cancer_Homo sapiens_hsa052300.50012104
111Salivary secretion_Homo sapiens_hsa049700.47936316
112Intestinal immune network for IgA production_Homo sapiens_hsa046720.47310153
113Oxytocin signaling pathway_Homo sapiens_hsa049210.45801651
114Metabolic pathways_Homo sapiens_hsa011000.41439891
115Systemic lupus erythematosus_Homo sapiens_hsa053220.41072646
116Legionellosis_Homo sapiens_hsa051340.40900955
117Graft-versus-host disease_Homo sapiens_hsa053320.40661069
118cAMP signaling pathway_Homo sapiens_hsa040240.40567634
119Gastric acid secretion_Homo sapiens_hsa049710.39276682
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.38935808
121Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.38627535
122Endocytosis_Homo sapiens_hsa041440.37341478
123Primary immunodeficiency_Homo sapiens_hsa053400.36881650
124Type I diabetes mellitus_Homo sapiens_hsa049400.35598273
125Dopaminergic synapse_Homo sapiens_hsa047280.34693347
126Taste transduction_Homo sapiens_hsa047420.34223663
127Circadian entrainment_Homo sapiens_hsa047130.34035409
128AMPK signaling pathway_Homo sapiens_hsa041520.33736283
129ABC transporters_Homo sapiens_hsa020100.33657023
130Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33320199
131Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33291337
132Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.31430572
133Asthma_Homo sapiens_hsa053100.31385916
134Pyrimidine metabolism_Homo sapiens_hsa002400.30664841
135Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.29193536
136VEGF signaling pathway_Homo sapiens_hsa043700.28948237
137Arginine and proline metabolism_Homo sapiens_hsa003300.28738747
138Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27895036
139Allograft rejection_Homo sapiens_hsa053300.27700099
140Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.27532026
141Sulfur metabolism_Homo sapiens_hsa009200.26909838
142Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.25803381
143Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.24911110
144Cell cycle_Homo sapiens_hsa041100.23770789
145N-Glycan biosynthesis_Homo sapiens_hsa005100.21183158
146Cocaine addiction_Homo sapiens_hsa050300.17619468
147Pentose and glucuronate interconversions_Homo sapiens_hsa000400.16460996
148RNA degradation_Homo sapiens_hsa030180.16068526
149Wnt signaling pathway_Homo sapiens_hsa043100.12743186
150Glutamatergic synapse_Homo sapiens_hsa047240.11783484
151Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.09876297
152Alcoholism_Homo sapiens_hsa050340.06638599
153Salmonella infection_Homo sapiens_hsa051320.06285497
154HIF-1 signaling pathway_Homo sapiens_hsa040660.03929524
155Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.03367395

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