TEX37

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.23465777
2epithelial cilium movement (GO:0003351)9.20612604
3plasma membrane fusion (GO:0045026)9.14489930
4reproduction (GO:0000003)9.05620210
5motile cilium assembly (GO:0044458)8.99367817
6regulation of cilium movement (GO:0003352)8.73376072
7histone H3-K9 demethylation (GO:0033169)8.69996447
8negative regulation of inclusion body assembly (GO:0090084)8.03414645
9cilium movement (GO:0003341)7.38972736
10synaptonemal complex assembly (GO:0007130)7.34515273
11synaptonemal complex organization (GO:0070193)7.34154765
12sperm capacitation (GO:0048240)7.24717659
13cilium or flagellum-dependent cell motility (GO:0001539)7.13132351
14spermatogenesis (GO:0007283)7.10855143
15male gamete generation (GO:0048232)7.08306793
16single fertilization (GO:0007338)7.07827599
17organic cation transport (GO:0015695)7.01250550
18male meiosis (GO:0007140)6.80603526
19microtubule depolymerization (GO:0007019)6.75168356
20response to pheromone (GO:0019236)6.69313606
21regulation of inclusion body assembly (GO:0090083)6.62469717
22epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.59116777
23gamete generation (GO:0007276)6.51378745
24chromosome condensation (GO:0030261)6.46152766
25piRNA metabolic process (GO:0034587)6.28952369
26DNA packaging (GO:0006323)6.10478099
27fertilization (GO:0009566)6.08185224
28oocyte development (GO:0048599)5.93645547
29calcium ion-dependent exocytosis (GO:0017156)5.80415739
30regulation of acrosome reaction (GO:0060046)5.78621580
31spermatid nucleus differentiation (GO:0007289)5.62133719
32centriole replication (GO:0007099)5.61566935
33germ cell development (GO:0007281)5.52655979
34cellular process involved in reproduction in multicellular organism (GO:0022412)5.40113825
35glycerol ether metabolic process (GO:0006662)5.35222171
36rRNA methylation (GO:0031167)5.26909833
37rRNA modification (GO:0000154)5.17448650
38regulation of microtubule-based movement (GO:0060632)5.12514125
39multicellular organismal reproductive process (GO:0048609)5.10840622
40regulation of female gonad development (GO:2000194)5.10456137
41cell recognition (GO:0008037)5.00876716
42sexual reproduction (GO:0019953)4.99483137
43microtubule severing (GO:0051013)4.98872776
44ether metabolic process (GO:0018904)4.94792237
45chromosome organization involved in meiosis (GO:0070192)4.88446701
46single strand break repair (GO:0000012)4.83825005
47ventricular system development (GO:0021591)4.79170420
48male meiosis I (GO:0007141)4.72150834
49seminiferous tubule development (GO:0072520)4.61846558
50positive regulation of meiosis (GO:0045836)4.38543687
51centriole assembly (GO:0098534)4.36239429
52chaperone-mediated protein complex assembly (GO:0051131)4.34311567
53positive regulation of meiotic cell cycle (GO:0051446)4.27620323
54meiotic nuclear division (GO:0007126)4.15299815
55multicellular organismal development (GO:0007275)4.11934043
56DNA methylation involved in gamete generation (GO:0043046)4.11279993
57regulation of meiosis I (GO:0060631)4.06058501
58left/right pattern formation (GO:0060972)4.03649970
59meiosis I (GO:0007127)3.84460845
60sequestering of actin monomers (GO:0042989)3.84310868
61protein targeting to Golgi (GO:0000042)3.73304738
62regulation of DNA methylation (GO:0044030)3.70914578
63regulation of spindle checkpoint (GO:0090231)3.67445426
64regulation of centriole replication (GO:0046599)3.66016457
65establishment of protein localization to Golgi (GO:0072600)3.58910341
66protein polyglutamylation (GO:0018095)3.58315344
67regulation of histone H3-K9 methylation (GO:0051570)3.56934678
68histone lysine demethylation (GO:0070076)3.50477992
69regulation of exit from mitosis (GO:0007096)3.50171140
70microtubule polymerization or depolymerization (GO:0031109)3.47086061
71polyamine biosynthetic process (GO:0006596)3.45255095
72negative regulation of histone methylation (GO:0031061)3.45064020
73protein kinase C signaling (GO:0070528)3.44837667
74phosphatidylethanolamine biosynthetic process (GO:0006646)3.43217659
75N-terminal protein amino acid acetylation (GO:0006474)3.41828911
76protein refolding (GO:0042026)3.37402809
77histone demethylation (GO:0016577)3.35188674
78protein K11-linked deubiquitination (GO:0035871)3.34353701
79retrograde transport, vesicle recycling within Golgi (GO:0000301)3.34056755
80nucleus organization (GO:0006997)3.32136410
81genitalia morphogenesis (GO:0035112)3.31915744
82interferon-gamma secretion (GO:0072643)3.29339506
83positive regulation of macrophage activation (GO:0043032)3.25979009
84gonadal mesoderm development (GO:0007506)3.25429386
85phosphatidylethanolamine metabolic process (GO:0046337)3.24710630
86mitotic metaphase plate congression (GO:0007080)3.20501062
87cellular response to pH (GO:0071467)3.19944455
88monoubiquitinated protein deubiquitination (GO:0035520)3.19558865
89meiotic cell cycle (GO:0051321)3.19133381
90mitotic sister chromatid cohesion (GO:0007064)3.18195225
91positive regulation of humoral immune response (GO:0002922)3.17507483
92chromatin silencing (GO:0006342)3.16069077
93regulation of meiosis (GO:0040020)3.13526587
94glycolytic process (GO:0006096)3.13144447
95histone exchange (GO:0043486)3.11836181
96negative regulation of reproductive process (GO:2000242)3.09697487
97RNA destabilization (GO:0050779)3.09027853
98mitochondrion degradation (GO:0000422)3.08028153
99positive regulation of uterine smooth muscle contraction (GO:0070474)3.06243507
100nucleoside diphosphate phosphorylation (GO:0006165)3.05493006
101RNA localization (GO:0006403)3.02496919
102carnitine transport (GO:0015879)3.01895555
103amino-acid betaine transport (GO:0015838)3.01895555
104negative regulation of gene silencing (GO:0060969)3.01158933
105female gamete generation (GO:0007292)2.98633642
106protein dealkylation (GO:0008214)2.98406918
107protein demethylation (GO:0006482)2.98406918
108centrosome duplication (GO:0051298)2.97827668
109regulation of cytokine production involved in inflammatory response (GO:1900015)2.95859071
110response to acidic pH (GO:0010447)2.93527420
111positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.93304832
112meiotic cell cycle process (GO:1903046)2.90947535
113polyol catabolic process (GO:0046174)2.88565926
114positive regulation of Rab GTPase activity (GO:0032851)2.88551996
115regulation of Rab GTPase activity (GO:0032313)2.88551996
116alditol metabolic process (GO:0019400)2.86249927
117gene silencing (GO:0016458)2.85702246
118regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.84583932
119carnitine transmembrane transport (GO:1902603)2.81013790
120protein localization to cilium (GO:0061512)2.76913709
121synapsis (GO:0007129)2.76056490
122GTP biosynthetic process (GO:0006183)2.74643490
123regulation of cilium assembly (GO:1902017)2.68056536
124membrane protein intracellular domain proteolysis (GO:0031293)2.59267238
125cilium organization (GO:0044782)2.52727700
126protein localization to chromosome, centromeric region (GO:0071459)2.48517905
127protein-DNA complex disassembly (GO:0032986)2.47470127
128nucleosome disassembly (GO:0006337)2.47470127
129cellular component assembly involved in morphogenesis (GO:0010927)2.45975237
130UTP biosynthetic process (GO:0006228)2.44994725
131positive regulation of glycolytic process (GO:0045821)2.44578989
132cilium assembly (GO:0042384)2.42308095
133negative regulation of gene expression, epigenetic (GO:0045814)2.42161767
134peptidyl-glutamic acid modification (GO:0018200)2.42127158
135microtubule-based movement (GO:0007018)2.40735245
136negative regulation of retinoic acid receptor signaling pathway (GO:0048387)15.2244593
137sperm motility (GO:0030317)14.5806870
138cell wall macromolecule metabolic process (GO:0044036)13.2449442
139cell wall macromolecule catabolic process (GO:0016998)13.2449442
140acrosome reaction (GO:0007340)12.8291082
141regulation of retinoic acid receptor signaling pathway (GO:0048385)12.7242196
142fusion of sperm to egg plasma membrane (GO:0007342)12.0475438
143acrosome assembly (GO:0001675)11.6775626
144sperm-egg recognition (GO:0035036)11.6214805
145binding of sperm to zona pellucida (GO:0007339)10.6344600
146cell-cell recognition (GO:0009988)10.3923332
147multicellular organism reproduction (GO:0032504)10.2165937
148spermatid development (GO:0007286)10.0862538

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.73904045
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.03243120
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.92063756
4EZH2_22144423_ChIP-Seq_EOC_Human3.89653620
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.86300055
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.69704407
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.16600112
8RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.98350674
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.80990014
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.78673427
11VDR_22108803_ChIP-Seq_LS180_Human2.73375040
12GATA1_26923725_Chip-Seq_HPCs_Mouse2.50787198
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.40819729
14CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.29955668
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.25452759
16AUTS2_25519132_ChIP-Seq_293T-REX_Human2.23299249
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.20551329
18EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.02221323
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.01801780
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.01487214
21ZNF274_21170338_ChIP-Seq_K562_Hela2.00426412
22RAC3_21632823_ChIP-Seq_H3396_Human1.92118789
23FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.89612375
24KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.89434699
25UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.85325133
26TP63_19390658_ChIP-ChIP_HaCaT_Human1.84617135
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.83163823
28FLI1_27457419_Chip-Seq_LIVER_Mouse1.82468523
29SOX2_22085726_ChIP-Seq_NPCs_Mouse1.79370042
30STAT1_17558387_ChIP-Seq_HELA_Human1.78224856
31KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.75265559
32KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.75265559
33KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.75265559
34GATA3_21867929_ChIP-Seq_CD8_Mouse1.74576552
35MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.72373101
36ELK4_26923725_Chip-Seq_MESODERM_Mouse1.72120736
37NOTCH1_21737748_ChIP-Seq_TLL_Human1.68614995
38TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.63805209
39FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.59528898
40FOXM1_23109430_ChIP-Seq_U2OS_Human1.58972571
41ERA_21632823_ChIP-Seq_H3396_Human1.56880854
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.54823668
43KAP1_22055183_ChIP-Seq_ESCs_Mouse1.53164657
44SMAD4_21741376_ChIP-Seq_EPCs_Human1.52573268
45TOP2B_26459242_ChIP-Seq_MCF-7_Human1.52150252
46AR_25329375_ChIP-Seq_VCAP_Human1.50575217
47GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.50549162
48PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.49790208
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.46951752
50ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45160039
51OCT4_20526341_ChIP-Seq_ESCs_Human1.44484770
52CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.43742137
53VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.41461803
54TAL1_26923725_Chip-Seq_HPCs_Mouse1.40537540
55GATA3_21867929_ChIP-Seq_TH1_Mouse1.40283866
56SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.39555195
57KDM2B_26808549_Chip-Seq_REH_Human1.39097508
58P53_21459846_ChIP-Seq_SAOS-2_Human1.38928153
59RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.38782041
60LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.37450287
61WDR5_24793694_ChIP-Seq_LNCAP_Human1.37225830
62MYC_19829295_ChIP-Seq_ESCs_Human1.36496660
63CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35719631
64GF1_26923725_Chip-Seq_HPCs_Mouse1.35654804
65RUNX2_22187159_ChIP-Seq_PCA_Human1.32873824
66P300_19829295_ChIP-Seq_ESCs_Human1.32737129
67REST_21632747_ChIP-Seq_MESCs_Mouse1.32666446
68NCOR_22424771_ChIP-Seq_293T_Human1.32664216
69CBP_20019798_ChIP-Seq_JUKART_Human1.31939885
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31939885
71RBPJ_21746931_ChIP-Seq_IB4_Human1.31877444
72PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.31708117
73TAF2_19829295_ChIP-Seq_ESCs_Human1.31579630
74SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30815067
75ETV1_20927104_ChIP-Seq_GIST48_Human1.30787012
76PRDM14_20953172_ChIP-Seq_ESCs_Human1.30323149
77SPI1_26923725_Chip-Seq_HPCs_Mouse1.29035461
78BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27989758
79KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27584656
80RXRA_24833708_ChIP-Seq_LIVER_Mouse1.26290834
81RAD21_21589869_ChIP-Seq_MESCs_Mouse1.25584231
82TBL1_22424771_ChIP-Seq_293T_Human1.25150352
83CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.24848094
84TET1_21451524_ChIP-Seq_MESCs_Mouse1.23333898
85GATA3_26560356_Chip-Seq_TH1_Human1.23275599
86HOXB7_26014856_ChIP-Seq_BT474_Human1.21481783
87SMAD4_21799915_ChIP-Seq_A2780_Human1.21359699
88CBX2_27304074_Chip-Seq_ESCs_Mouse1.19693170
89E2F1_20622854_ChIP-Seq_HELA_Human1.18624232
90CBP_21632823_ChIP-Seq_H3396_Human1.18183430
91FOXH1_21741376_ChIP-Seq_EPCs_Human1.17924168
92TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17297622
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.16668453
94JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.16302809
95SMRT_27268052_Chip-Seq_Bcells_Human1.16056467
96SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.16020966
97RARA_24833708_ChIP-Seq_LIVER_Mouse1.15953359
98FLI1_21867929_ChIP-Seq_TH2_Mouse1.15712611
99SOX2_19829295_ChIP-Seq_ESCs_Human1.15470847
100NANOG_19829295_ChIP-Seq_ESCs_Human1.15470847
101RUNX1_26923725_Chip-Seq_HPCs_Mouse1.15301247
102GATA1_19941827_ChIP-Seq_MEL86_Mouse1.14959878
103TCF4_23295773_ChIP-Seq_U87_Human1.14935476
104CTBP2_25329375_ChIP-Seq_LNCAP_Human1.14453017
105STAT3_23295773_ChIP-Seq_U87_Human1.14230529
106MYC_27129775_Chip-Seq_CORNEA_Mouse1.14107514
107PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13320922
108TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.13307157
109ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.12548980
110ESET_19884257_ChIP-Seq_ESCs_Mouse1.12452571
111GATA3_21878914_ChIP-Seq_MCF-7_Human1.12122573
112ERG_20517297_ChIP-Seq_VCAP_Human1.11407760
113RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.10929858
114PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.10668862
115SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10414711
116POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10382498
117TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10382498
118HNFA_21074721_ChIP-Seq_CACO-2_Human1.09663992
119TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08779267
120YY1_22570637_ChIP-Seq_MALME-3M_Human1.08724992
121EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.08011513
122OCT4_19829295_ChIP-Seq_ESCs_Human1.07630219
123P300_27268052_Chip-Seq_Bcells_Human1.07489160
124CTCF_20526341_ChIP-Seq_ESCs_Human1.07280768
125ER_23166858_ChIP-Seq_MCF-7_Human1.06493784
126FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.05887435
127PHF8_20622853_ChIP-Seq_HELA_Human1.05506892
128LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse1.04787270
129BCOR_27268052_Chip-Seq_Bcells_Human1.04388442
130SMAD3_21741376_ChIP-Seq_ESCs_Human1.04342188
131SOX11_22085726_ChIP-Seq_ESNs_Mouse1.04012697
132CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.03921178
133KLF4_19829295_ChIP-Seq_ESCs_Human1.01029191
134SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00879430
135CRX_20693478_ChIP-Seq_RETINA_Mouse1.00704225
136EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00252906
137PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00001531
138TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99636632
139FLI1_21867929_ChIP-Seq_CD8_Mouse0.99634997
140SMAD4_21741376_ChIP-Seq_HESCs_Human0.99450556
141RNF2_27304074_Chip-Seq_NSC_Mouse0.99397465
142IRF1_19129219_ChIP-ChIP_H3396_Human0.99200068
143NANOG_18555785_Chip-Seq_ESCs_Mouse0.98964082
144SMAD3_21741376_ChIP-Seq_EPCs_Human0.98457607
145GBX2_23144817_ChIP-Seq_PC3_Human0.97145373
146ELF1_20517297_ChIP-Seq_JURKAT_Human0.96588311
147CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.96103311
148TAF15_26573619_Chip-Seq_HEK293_Human0.96042661
149PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.95925720
150P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.95535658
151SMC3_22415368_ChIP-Seq_MEFs_Mouse0.95473701
152FUS_26573619_Chip-Seq_HEK293_Human0.95238066
153TP63_22573176_ChIP-Seq_HFKS_Human0.94845666
154NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94616488
155RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.94371258
156SRY_22984422_ChIP-ChIP_TESTIS_Rat0.94059237
157MYC_18940864_ChIP-ChIP_HL60_Human0.93446583
158NANOG_20526341_ChIP-Seq_ESCs_Human0.92523480
159EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.92217219
160OCT4_18555785_Chip-Seq_ESCs_Mouse0.92147775
161ETV2_25802403_ChIP-Seq_MESCs_Mouse0.90705367
162BCL6_27268052_Chip-Seq_Bcells_Human0.89180890
163SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.88771524
164NFYB_21822215_ChIP-Seq_K562_Human0.88741768
165PHF8_20622854_ChIP-Seq_HELA_Human0.88523437
166NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.87636396

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.06662318
2MP0001929_abnormal_gametogenesis5.59338063
3MP0006292_abnormal_olfactory_placode4.81395131
4MP0008877_abnormal_DNA_methylation3.79825399
5MP0002161_abnormal_fertility/fecundity3.33781116
6MP0002210_abnormal_sex_determination3.31932174
7MP0005670_abnormal_white_adipose3.17710158
8MP0003693_abnormal_embryo_hatching2.86203443
9MP0001145_abnormal_male_reproductive2.82287203
10MP0000678_abnormal_parathyroid_gland2.70886753
11MP0005423_abnormal_somatic_nervous2.57810516
12MP0000653_abnormal_sex_gland2.44051161
13MP0001986_abnormal_taste_sensitivity2.25726296
14MP0002653_abnormal_ependyma_morphology2.01410234
15MP0005410_abnormal_fertilization16.7853540
16MP0009379_abnormal_foot_pigmentation1.88897610
17MP0003136_yellow_coat_color1.87128485
18MP0005395_other_phenotype1.75085393
19MP0002138_abnormal_hepatobiliary_system1.72579991
20MP0001666_abnormal_nutrient_absorption1.67002951
21MP0003646_muscle_fatigue1.65950469
22MP0002127_abnormal_cardiovascular_syste1.60802089
23MP0004233_abnormal_muscle_weight1.45789187
24MP0005394_taste/olfaction_phenotype1.37970192
25MP0005499_abnormal_olfactory_system1.37970192
26MP0005360_urolithiasis1.35046856
27MP0008789_abnormal_olfactory_epithelium1.33427737
28MP0000049_abnormal_middle_ear1.32531183
29MP0002160_abnormal_reproductive_system1.31810668
30MP0004957_abnormal_blastocyst_morpholog1.31478819
31MP0006072_abnormal_retinal_apoptosis1.29671176
32MP0005379_endocrine/exocrine_gland_phen1.22005469
33MP0000427_abnormal_hair_cycle1.20739082
34MP0003283_abnormal_digestive_organ1.19244223
35MP0003119_abnormal_digestive_system1.18942681
36MP0006276_abnormal_autonomic_nervous1.18622735
37MP0001765_abnormal_ion_homeostasis1.07427941
38MP0002234_abnormal_pharynx_morphology1.07056107
39MP0005623_abnormal_meninges_morphology1.04517010
40MP0003890_abnormal_embryonic-extraembry1.03678834
41MP0001984_abnormal_olfaction1.01582935
42MP0010368_abnormal_lymphatic_system0.97756076
43MP0008058_abnormal_DNA_repair0.97033845
44MP0009840_abnormal_foam_cell0.95262416
45MP0002282_abnormal_trachea_morphology0.92807609
46MP0001348_abnormal_lacrimal_gland0.87600872
47MP0003936_abnormal_reproductive_system0.87374914
48MP0001963_abnormal_hearing_physiology0.87081302
49MP0002229_neurodegeneration0.87074651
50MP0001486_abnormal_startle_reflex0.83970590
51MP0001485_abnormal_pinna_reflex0.83841783
52MP0002249_abnormal_larynx_morphology0.83239199
53MP0009046_muscle_twitch0.77585448
54MP0000026_abnormal_inner_ear0.74525426
55MP0005647_abnormal_sex_gland0.72571266
56MP0002735_abnormal_chemical_nociception0.72423341
57MP0008995_early_reproductive_senescence0.71587226
58MP0001502_abnormal_circadian_rhythm0.70614452
59MP0005636_abnormal_mineral_homeostasis0.67974251
60MP0002095_abnormal_skin_pigmentation0.66731592
61MP0005389_reproductive_system_phenotype0.66096335
62MP0003115_abnormal_respiratory_system0.64495191
63MP0003011_delayed_dark_adaptation0.62847141
64MP0003329_amyloid_beta_deposits0.61884822
65MP0004036_abnormal_muscle_relaxation0.61235714
66MP0002272_abnormal_nervous_system0.61151860
67MP0000470_abnormal_stomach_morphology0.61032880
68MP0002067_abnormal_sensory_capabilities0.59559414
69MP0001664_abnormal_digestion0.57956510
70MP0005666_abnormal_adipose_tissue0.56997031
71MP0000631_abnormal_neuroendocrine_gland0.56934726
72MP0002736_abnormal_nociception_after0.56841497
73MP0003183_abnormal_peptide_metabolism0.56379961
74MP0005397_hematopoietic_system_phenotyp0.55826181
75MP0001545_abnormal_hematopoietic_system0.55826181
76MP0000350_abnormal_cell_proliferation0.54935686
77MP0003111_abnormal_nucleus_morphology0.54904431
78MP0003878_abnormal_ear_physiology0.54827809
79MP0005377_hearing/vestibular/ear_phenot0.54827809
80MP0001286_abnormal_eye_development0.53201672
81MP0001764_abnormal_homeostasis0.52952167
82MP0008932_abnormal_embryonic_tissue0.52128853
83MP0003699_abnormal_female_reproductive0.51752429
84MP0002734_abnormal_mechanical_nocicepti0.51657548
85MP0002085_abnormal_embryonic_tissue0.50913881
86MP0005310_abnormal_salivary_gland0.50439581
87MP0005085_abnormal_gallbladder_physiolo0.50352145
88MP0003252_abnormal_bile_duct0.50336213
89MP0005451_abnormal_body_composition0.50332272
90MP0006036_abnormal_mitochondrial_physio0.48433923
91MP0003959_abnormal_lean_body0.47613455
92MP0005646_abnormal_pituitary_gland0.47610463
93MP0001324_abnormal_eye_pigmentation0.46906790
94MP0000534_abnormal_ureter_morphology0.46460150
95MP0010094_abnormal_chromosome_stability0.45968008
96MP0009745_abnormal_behavioral_response0.45855169
97MP0002269_muscular_atrophy0.45721017
98MP0003121_genomic_imprinting0.45375735
99MP0001293_anophthalmia0.45181298
100MP0000358_abnormal_cell_content/0.43358318
101MP0001881_abnormal_mammary_gland0.42725819
102MP0001440_abnormal_grooming_behavior0.41845994
103MP0000681_abnormal_thyroid_gland0.41459585
104MP0009115_abnormal_fat_cell0.38703225
105MP0009278_abnormal_bone_marrow0.37448620
106MP0005253_abnormal_eye_physiology0.35427858
107MP0001730_embryonic_growth_arrest0.34922790
108MP0003879_abnormal_hair_cell0.32563669
109MP0000604_amyloidosis0.31818676
110MP0001968_abnormal_touch/_nociception0.30903986
111MP0004133_heterotaxia0.30625041
112MP0004019_abnormal_vitamin_homeostasis0.30253690
113MP0005391_vision/eye_phenotype0.29866222
114MP0005551_abnormal_eye_electrophysiolog0.29681802
115MP0002169_no_abnormal_phenotype0.29651807
116MP0001119_abnormal_female_reproductive0.29511764
117MP0002873_normal_phenotype0.29494842
118MP0002928_abnormal_bile_duct0.28096668
119MP0002102_abnormal_ear_morphology0.27350562
120MP0006035_abnormal_mitochondrial_morpho0.26719590
121MP0003786_premature_aging0.26504919
122MP0003942_abnormal_urinary_system0.26186116
123MP0002971_abnormal_brown_adipose0.25971266
124MP0004811_abnormal_neuron_physiology0.25318550
125MP0002796_impaired_skin_barrier0.24519954
126MP0002139_abnormal_hepatobiliary_system0.24315199
127MP0003861_abnormal_nervous_system0.22556912
128MP0004084_abnormal_cardiac_muscle0.21945974
129MP0003633_abnormal_nervous_system0.21555421
130MP0000569_abnormal_digit_pigmentation0.20561231
131MP0003948_abnormal_gas_homeostasis0.20528235
132MP0003631_nervous_system_phenotype0.20033233
133MP0004742_abnormal_vestibular_system0.19859917
134MP0002092_abnormal_eye_morphology0.18994280
135MP0010307_abnormal_tumor_latency0.18823726
136MP0001849_ear_inflammation0.18411502
137MP0002152_abnormal_brain_morphology0.18261597
138MP0000001_mammalian_phenotype0.17381816
139MP0001661_extended_life_span0.16237919
140MP0001672_abnormal_embryogenesis/_devel0.14869785
141MP0005380_embryogenesis_phenotype0.14869785
142MP0000462_abnormal_digestive_system0.14702225
143MP0003950_abnormal_plasma_membrane0.14452386
144MP0003077_abnormal_cell_cycle0.14361091
145MP0008007_abnormal_cellular_replicative0.14061015
146MP0004145_abnormal_muscle_electrophysio0.13299460
147MP0002084_abnormal_developmental_patter0.12939971
148MP0002132_abnormal_respiratory_system0.12933426
149MP0002693_abnormal_pancreas_physiology0.12614039
150MP0003718_maternal_effect0.12275178
151MP0003787_abnormal_imprinting0.12182426
152MP0001697_abnormal_embryo_size0.11835652
153MP0009672_abnormal_birth_weight0.11774350
154MP0004043_abnormal_pH_regulation0.11772537
155MP0000313_abnormal_cell_death0.11710708
156MP0002909_abnormal_adrenal_gland0.11171800
157MP0005375_adipose_tissue_phenotype0.10915711
158MP0005365_abnormal_bile_salt0.10848048

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.38126986
2Abnormal respiratory motile cilium morphology (HP:0005938)9.14706012
3Abnormal respiratory epithelium morphology (HP:0012253)9.14706012
4Chronic bronchitis (HP:0004469)7.47704951
5Rhinitis (HP:0012384)7.33681835
6Infertility (HP:0000789)7.28752349
7Abnormal ciliary motility (HP:0012262)7.18096445
8Nasal polyposis (HP:0100582)6.37237193
9Male infertility (HP:0003251)5.46209066
10Abnormality of the nasal mucosa (HP:0000433)5.21841349
11Severe visual impairment (HP:0001141)4.98686807
12Bronchitis (HP:0012387)4.59383570
13Premature ovarian failure (HP:0008209)4.57577891
14Bronchiectasis (HP:0002110)4.34811549
15Bony spicule pigmentary retinopathy (HP:0007737)4.16380690
16Abnormal spermatogenesis (HP:0008669)4.11671126
17Supernumerary spleens (HP:0009799)3.92345218
18Nephronophthisis (HP:0000090)3.90145757
19Attenuation of retinal blood vessels (HP:0007843)3.76326286
20Median cleft lip (HP:0000161)3.64076258
21Osteomalacia (HP:0002749)3.64030162
22Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.60368556
23Recurrent otitis media (HP:0000403)3.25621287
24Recurrent sinusitis (HP:0011108)3.14763889
25Hypophosphatemic rickets (HP:0004912)3.08687642
26Congenital stationary night blindness (HP:0007642)3.08191105
27Short tibia (HP:0005736)3.07085448
28Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.99067912
29Abnormal rod and cone electroretinograms (HP:0008323)2.93247793
30Aplasia/Hypoplasia of the fovea (HP:0008060)2.92842891
31Hypoplasia of the fovea (HP:0007750)2.92842891
32Abnormality of abdominal situs (HP:0011620)2.92361222
33Abdominal situs inversus (HP:0003363)2.92361222
34Aplasia/Hypoplasia of the tibia (HP:0005772)2.90955186
35Impulsivity (HP:0100710)2.90473990
36Abnormality of the renal medulla (HP:0100957)2.89612344
37Congenital sensorineural hearing impairment (HP:0008527)2.87783594
38Chronic hepatic failure (HP:0100626)2.82837067
39Aplasia/Hypoplasia of the earlobes (HP:0009906)2.77501197
40Anterior segment dysgenesis (HP:0007700)2.74647242
41Chronic sinusitis (HP:0011109)2.69162024
42Hypergonadotropic hypogonadism (HP:0000815)2.67261015
43Recurrent bronchitis (HP:0002837)2.67169316
44Preauricular pit (HP:0004467)2.65961789
45Periauricular skin pits (HP:0100277)2.65961789
46Oligodactyly (hands) (HP:0001180)2.62409786
47Cone-rod dystrophy (HP:0000548)2.62307875
48Tubular atrophy (HP:0000092)2.58652470
49Azoospermia (HP:0000027)2.52556768
50Abnormality of midbrain morphology (HP:0002418)2.52270158
51Molar tooth sign on MRI (HP:0002419)2.52270158
52Tubulointerstitial nephritis (HP:0001970)2.48062130
53Cholecystitis (HP:0001082)2.45788159
54Abnormal gallbladder physiology (HP:0012438)2.45788159
55Abnormality of macular pigmentation (HP:0008002)2.41632323
56Enlarged epiphyses (HP:0010580)2.38139027
57Amelogenesis imperfecta (HP:0000705)2.36745544
58Abnormality of the fovea (HP:0000493)2.36712904
59Generalized aminoaciduria (HP:0002909)2.36458166
60Skin pits (HP:0100276)2.36169689
61Tubulointerstitial abnormality (HP:0001969)2.34971781
62Tetany (HP:0001281)2.32587986
63Dyschromatopsia (HP:0007641)2.31746624
64Prostate neoplasm (HP:0100787)2.24613302
65Medial flaring of the eyebrow (HP:0010747)2.22008543
66Congenital malformation of the right heart (HP:0011723)2.20490967
67Double outlet right ventricle (HP:0001719)2.20490967
68Hyperkalemia (HP:0002153)2.17928069
69Choroideremia (HP:0001139)2.17514555
70Potter facies (HP:0002009)2.15195074
71Facial shape deformation (HP:0011334)2.15195074
72Decreased central vision (HP:0007663)2.14820778
73Proximal tubulopathy (HP:0000114)2.09686020
74Gonadotropin excess (HP:0000837)2.09512848
75Malnutrition (HP:0004395)2.08209694
76Tubulointerstitial fibrosis (HP:0005576)2.07508364
77Progressive external ophthalmoplegia (HP:0000590)2.06845035
78Myokymia (HP:0002411)2.06708230
79Chromosomal breakage induced by crosslinking agents (HP:0003221)2.03141033
80Resting tremor (HP:0002322)2.01857038
81Dynein arm defect of respiratory motile cilia (HP:0012255)13.2214931
82Absent/shortened dynein arms (HP:0200106)13.2214931
83Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1302189
84Abnormal auditory evoked potentials (HP:0006958)1.99760411
85Truncal obesity (HP:0001956)1.98572218
86Spastic tetraparesis (HP:0001285)1.97897690
87Optic nerve hypoplasia (HP:0000609)1.97296200
88Chromsome breakage (HP:0040012)1.97259020
89Recurrent pneumonia (HP:0006532)1.95436702
90Abnormality of the ileum (HP:0001549)1.95246781
91Meckel diverticulum (HP:0002245)1.94149464
92Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.90560312
93Atonic seizures (HP:0010819)1.89650983
94Hemorrhage of the eye (HP:0011885)1.88601376
95Abnormality of dental color (HP:0011073)1.87753716
96Glossoptosis (HP:0000162)1.85627953
97Genu varum (HP:0002970)1.84757551
98Abnormality of urine glucose concentration (HP:0011016)1.84407536
99Glycosuria (HP:0003076)1.84407536
100Subcapsular cataract (HP:0000523)1.83831346
101Abnormality of the costochondral junction (HP:0000919)1.83455190
102Polydipsia (HP:0001959)1.77463251
103Abnormal drinking behavior (HP:0030082)1.77463251
104Pendular nystagmus (HP:0012043)1.76806775
105Maternal diabetes (HP:0009800)1.75649386
106Abnormality of the aortic arch (HP:0012303)1.75533482
107Hypoplastic ischia (HP:0003175)1.75523043
108Abnormality of the labia minora (HP:0012880)1.75393904
109Neurofibrillary tangles (HP:0002185)1.74491849
110Decreased electroretinogram (ERG) amplitude (HP:0000654)1.74096480
111Facial cleft (HP:0002006)1.74056374
112Progressive sensorineural hearing impairment (HP:0000408)1.72167186
113Abnormal number of incisors (HP:0011064)1.70265581
114Postaxial foot polydactyly (HP:0001830)1.69890977
115Aplasia/Hypoplasia of the uvula (HP:0010293)1.69880964
116Aplasia/Hypoplasia of the macula (HP:0008059)1.69385404
117Underdeveloped nasal alae (HP:0000430)1.69302359
118Photophobia (HP:0000613)1.69161425
119Postural instability (HP:0002172)1.69007031
120Bile duct proliferation (HP:0001408)1.64650402
121Abnormal biliary tract physiology (HP:0012439)1.64650402
122Bundle branch block (HP:0011710)1.64436653
123Abnormality of renal excretion (HP:0011036)1.63249405
124Congenital hepatic fibrosis (HP:0002612)1.62655294
125Stage 5 chronic kidney disease (HP:0003774)1.59257241
126Hypoplasia of the capital femoral epiphysis (HP:0003090)1.55660960
127Abnormality of the renal cortex (HP:0011035)1.54551516
128Exercise-induced myalgia (HP:0003738)1.52852014
129Aplasia/Hypoplasia of the lens (HP:0008063)1.50674236
130Heterotopia (HP:0002282)1.49085751
131Easy fatigability (HP:0003388)1.48326966
132Short ribs (HP:0000773)1.43989218
133Asymmetric septal hypertrophy (HP:0001670)1.42602010
134Abnormal urine output (HP:0012590)1.42064138
135Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.41704276
136Bell-shaped thorax (HP:0001591)1.41655360
137Oculomotor apraxia (HP:0000657)1.40403833
138Cleft eyelid (HP:0000625)1.40324874
139Constricted visual fields (HP:0001133)1.37686989
140Cerebral inclusion bodies (HP:0100314)1.37073257
141Sensory axonal neuropathy (HP:0003390)1.36837143
142Myoglobinuria (HP:0002913)1.35855888
143Fatigable weakness (HP:0003473)1.34676591
144Abnormality of the neuromuscular junction (HP:0003398)1.34676591
145Hypercholesterolemia (HP:0003124)1.33939340
146Abnormality of permanent molar morphology (HP:0011071)1.33345767
147Abnormality of the dental root (HP:0006486)1.33345767
148Taurodontia (HP:0000679)1.33345767
149Postaxial hand polydactyly (HP:0001162)1.33238832
150Pancreatic fibrosis (HP:0100732)1.32824431
151Renal dysplasia (HP:0000110)1.32793140
152Rhabdomyolysis (HP:0003201)1.27090373
153Abnormality of the dental pulp (HP:0006479)1.25254934
154Cystic liver disease (HP:0006706)1.25254570
155Deformed sella turcica (HP:0002681)1.25236700
156Abnormal ventriculo-arterial connection (HP:0011563)1.24511067
157Transposition of the great arteries (HP:0001669)1.24511067
158Abnormal connection of the cardiac segments (HP:0011545)1.24511067
159Absent eyebrow (HP:0002223)1.24313702
160Exercise-induced muscle cramps (HP:0003710)1.24244463
161Abnormality of molar morphology (HP:0011070)1.22506139
162Abnormality of molar (HP:0011077)1.22506139
163Absent epiphyses (HP:0010577)1.20855731
164Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.20855731
165Loss of speech (HP:0002371)1.19174063
166Aplasia/Hypoplasia affecting the retina (HP:0008061)1.18823815
167Short nail (HP:0001799)1.18594092
168Personality changes (HP:0000751)1.17505092
169Type 2 muscle fiber atrophy (HP:0003554)1.17307896
170Abnormality of dentin (HP:0010299)1.17172680
171Fibular hypoplasia (HP:0003038)1.16576250
172Decreased muscle mass (HP:0003199)1.16236664
173Polyuria (HP:0000103)1.15211807

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.55547581
2PDK37.55547581
3TESK16.92561286
4PRKD35.46957667
5ICK4.97189433
6PDK24.87027807
7STK162.73134817
8GRK12.53193463
9MAP3K92.30347349
10CDK122.25408677
11PTK2B2.20837673
12ZAK2.18195944
13DDR22.13645351
14STK382.12996053
15WNK42.07024294
16STK392.05027491
17INSRR2.03599201
18ARAF1.98849751
19MAP3K131.92433406
20CDK191.91799222
21LATS21.86381065
22NEK21.85250209
23DYRK1B1.77829544
24PLK21.75166197
25ACVR1B1.73421409
26CDK71.62011390
27MAP4K21.53765376
28PINK11.41311375
29PDK11.39482350
30PNCK1.33207508
31BRD41.26397169
32RIPK41.10042246
33DYRK31.07265461
34TNIK1.06846096
35PIK3CG1.06277996
36PDPK11.02681096
37TAOK30.98265497
38TRIM280.92914312
39TYRO30.84789134
40KSR20.82217173
41TTK0.81409675
42MAP3K80.80036254
43CCNB10.78573621
44MAPK150.76656917
45PBK0.76585489
46IRAK10.72347422
47MOS0.70089383
48CHEK20.69858539
49WNK10.69296452
50STK30.68857300
51EEF2K0.68766438
52STK38L0.66648827
53PKN10.66296863
54EIF2AK30.63553970
55TLK10.63024132
56VRK10.62490015
57PASK0.59305913
58TESK20.57831522
59MUSK0.57244377
60BMPR1B0.56772643
61CAMK1D0.53983259
62PLK30.52924537
63RAF10.52824799
64PLK40.50868213
65CDK90.48804065
66MAP2K60.45721469
67PRKCG0.45473239
68NTRK20.44834269
69NUAK10.44368904
70MST1R0.44226709
71PAK10.43450268
72LMTK20.41444748
73BRSK20.40809282
74PRKCI0.39929822
75MAPKAPK30.38979111
76MET0.37620010
77IRAK20.37546856
78WEE10.36957199
79CHEK10.36574406
80OXSR10.35336502
81MAPKAPK50.34584744
82MAP3K100.34377950
83EPHA40.34362129
84LATS10.33833037
85BUB10.33141535
86NTRK30.32983842
87MAPK110.31387842
88MAPK10.30542939
89CAMK10.30293967
90BRSK10.29603285
91PRKAA20.28691403
92CAMK1G0.27612093
93PAK40.26897492
94PRKCZ0.26288254
95PRKACB0.25484061
96CAMK40.25393716
97GRK70.24527491
98ATM0.24379616
99BRAF0.24175305
100MARK20.24159435
101CAMKK10.24083441
102PAK20.23987420
103CSNK1E0.23869766
104MELK0.23615217
105PLK10.23254691
106STK240.21778750
107CDK150.20909768
108ATR0.20714587
109PRKAA10.18393539
110CDK180.17788589
111CDK11A0.16648864
112MTOR0.16001790
113NEK60.15266499
114PRKCQ0.14950810
115STK100.13952799
116CSNK2A10.12869797
117CDK140.12696428
118MARK30.12605176
119RPS6KA10.11574761
120PIM10.11513794
121PRKG20.11401291
122STK110.10150893
123RPS6KB10.09694499
124AURKA0.09401387
125PRKCD0.08616660
126RPS6KA40.07484797
127CSF1R0.06680442
128CLK10.06401210
129GSK3B0.06395196
130CSNK2A20.05093052
131MAP3K50.04876638
132CDK60.04104945
133CDK20.03998848
134CDK30.03803785
135CDK10.02819378
136CDC70.02686430
137CAMK2A0.02000847
138PRKCA0.01654210
139PRKACG0.01625171
140MAPK80.01365386
141PRKCB0.00873776
142CDK40.00207701
143EGFR-0.0457661
144PRKACA-0.0344664
145PAK6-0.0342821
146ZAP70-0.0326076
147CSNK1D-0.0256759
148AKT3-0.0220921
149AURKB-0.0207778
150SRPK1-0.0075778
151WNK3-0.0066549
152PRKG1-0.0053933

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.97583813
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.29637218
3Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005334.10418434
4Vitamin B6 metabolism_Homo sapiens_hsa007503.88844587
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.51820196
6Linoleic acid metabolism_Homo sapiens_hsa005913.46311258
7Olfactory transduction_Homo sapiens_hsa047403.22279219
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.17631843
9Phototransduction_Homo sapiens_hsa047443.08552635
10Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.91576669
11Pyruvate metabolism_Homo sapiens_hsa006202.90938787
12Basal transcription factors_Homo sapiens_hsa030222.42579328
13Carbohydrate digestion and absorption_Homo sapiens_hsa049732.40669373
14Glucagon signaling pathway_Homo sapiens_hsa049222.38670597
15Mismatch repair_Homo sapiens_hsa034302.37272031
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.23983330
17Propanoate metabolism_Homo sapiens_hsa006402.23540739
18Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.21502523
19RNA polymerase_Homo sapiens_hsa030202.16132476
20Ribosome_Homo sapiens_hsa030102.14676526
21Glycerophospholipid metabolism_Homo sapiens_hsa005642.04442284
22Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.00179489
23Glycerolipid metabolism_Homo sapiens_hsa005611.94532946
24Homologous recombination_Homo sapiens_hsa034401.83335853
25PPAR signaling pathway_Homo sapiens_hsa033201.76245836
26Fat digestion and absorption_Homo sapiens_hsa049751.73021667
27Ether lipid metabolism_Homo sapiens_hsa005651.71025416
28Pentose phosphate pathway_Homo sapiens_hsa000301.70478692
29Folate biosynthesis_Homo sapiens_hsa007901.70034535
30Mineral absorption_Homo sapiens_hsa049781.68613123
31Ovarian steroidogenesis_Homo sapiens_hsa049131.67982928
32Fructose and mannose metabolism_Homo sapiens_hsa000511.67258572
33Selenocompound metabolism_Homo sapiens_hsa004501.66672319
34Oocyte meiosis_Homo sapiens_hsa041141.56905457
35Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.55952981
36Regulation of autophagy_Homo sapiens_hsa041401.51920831
37Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.47519134
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.44797283
39Fatty acid metabolism_Homo sapiens_hsa012121.41791341
40Fatty acid degradation_Homo sapiens_hsa000711.40772165
41Amphetamine addiction_Homo sapiens_hsa050311.40216298
42Base excision repair_Homo sapiens_hsa034101.38254454
43Carbon metabolism_Homo sapiens_hsa012001.31341372
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.30616559
45Cardiac muscle contraction_Homo sapiens_hsa042601.24378782
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23566462
47Purine metabolism_Homo sapiens_hsa002301.19921780
48p53 signaling pathway_Homo sapiens_hsa041151.18059916
49Collecting duct acid secretion_Homo sapiens_hsa049661.16172988
50Dorso-ventral axis formation_Homo sapiens_hsa043201.10120461
51Cysteine and methionine metabolism_Homo sapiens_hsa002701.09726915
52Glutathione metabolism_Homo sapiens_hsa004801.09273747
53Arachidonic acid metabolism_Homo sapiens_hsa005901.09211649
54Fanconi anemia pathway_Homo sapiens_hsa034601.07655877
55Glycosaminoglycan degradation_Homo sapiens_hsa005311.04948716
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.98503640
57Retinol metabolism_Homo sapiens_hsa008300.98166770
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.97838877
59Antigen processing and presentation_Homo sapiens_hsa046120.97662024
60Nucleotide excision repair_Homo sapiens_hsa034200.96714317
61Hedgehog signaling pathway_Homo sapiens_hsa043400.96584879
62Spliceosome_Homo sapiens_hsa030400.94405330
63RNA transport_Homo sapiens_hsa030130.92487901
64Biosynthesis of amino acids_Homo sapiens_hsa012300.88423446
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.85964904
66Autoimmune thyroid disease_Homo sapiens_hsa053200.83024842
67Adipocytokine signaling pathway_Homo sapiens_hsa049200.82439992
68Renin secretion_Homo sapiens_hsa049240.81828062
69Insulin secretion_Homo sapiens_hsa049110.80789248
70mRNA surveillance pathway_Homo sapiens_hsa030150.80755433
71Chemical carcinogenesis_Homo sapiens_hsa052040.80345573
72Morphine addiction_Homo sapiens_hsa050320.78582493
73Butanoate metabolism_Homo sapiens_hsa006500.77803989
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.77466534
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72528252
76Allograft rejection_Homo sapiens_hsa053300.72090127
77Nicotine addiction_Homo sapiens_hsa050330.71474029
78Primary bile acid biosynthesis_Homo sapiens_hsa001200.71210289
79Thyroid hormone synthesis_Homo sapiens_hsa049180.70954548
80Bile secretion_Homo sapiens_hsa049760.70430842
81Pyrimidine metabolism_Homo sapiens_hsa002400.69682219
82Huntingtons disease_Homo sapiens_hsa050160.69544187
83Renin-angiotensin system_Homo sapiens_hsa046140.67822087
84Herpes simplex infection_Homo sapiens_hsa051680.66568355
85Circadian rhythm_Homo sapiens_hsa047100.66451013
86Estrogen signaling pathway_Homo sapiens_hsa049150.65427059
87Serotonergic synapse_Homo sapiens_hsa047260.65272138
88Graft-versus-host disease_Homo sapiens_hsa053320.65239321
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63521662
90Caffeine metabolism_Homo sapiens_hsa002320.63493135
91Arginine and proline metabolism_Homo sapiens_hsa003300.63438074
92Steroid biosynthesis_Homo sapiens_hsa001000.62587617
93Long-term potentiation_Homo sapiens_hsa047200.61951138
94Aldosterone synthesis and secretion_Homo sapiens_hsa049250.61881654
95Pancreatic secretion_Homo sapiens_hsa049720.61276906
96cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60431453
97Systemic lupus erythematosus_Homo sapiens_hsa053220.60134758
98Type I diabetes mellitus_Homo sapiens_hsa049400.59832643
99Legionellosis_Homo sapiens_hsa051340.56262340
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.50557743
101Synaptic vesicle cycle_Homo sapiens_hsa047210.49235805
102Type II diabetes mellitus_Homo sapiens_hsa049300.48792530
103Salivary secretion_Homo sapiens_hsa049700.47270685
104GABAergic synapse_Homo sapiens_hsa047270.45747405
105Central carbon metabolism in cancer_Homo sapiens_hsa052300.45394020
106Viral carcinogenesis_Homo sapiens_hsa052030.44358126
107Protein digestion and absorption_Homo sapiens_hsa049740.44077729
108ABC transporters_Homo sapiens_hsa020100.43385451
109Metabolic pathways_Homo sapiens_hsa011000.43191225
110Endocytosis_Homo sapiens_hsa041440.42260363
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39480306
112Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.38655335
113Influenza A_Homo sapiens_hsa051640.38274753
114Drug metabolism - other enzymes_Homo sapiens_hsa009830.37329203
115Calcium signaling pathway_Homo sapiens_hsa040200.36289167
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36191001
117AMPK signaling pathway_Homo sapiens_hsa041520.36056721
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34339152
119Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.32140120
120Gastric acid secretion_Homo sapiens_hsa049710.31775135
121Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31141318
122Sulfur metabolism_Homo sapiens_hsa009200.30092164
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.28000852
124Cholinergic synapse_Homo sapiens_hsa047250.27758484
125Circadian entrainment_Homo sapiens_hsa047130.27481214
126Steroid hormone biosynthesis_Homo sapiens_hsa001400.27355263
127Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.27199536
128Inositol phosphate metabolism_Homo sapiens_hsa005620.27033703
129VEGF signaling pathway_Homo sapiens_hsa043700.26151655
130DNA replication_Homo sapiens_hsa030300.25237592
131Alcoholism_Homo sapiens_hsa050340.25228458
132Phenylalanine metabolism_Homo sapiens_hsa003600.24542287
133Phosphatidylinositol signaling system_Homo sapiens_hsa040700.23611459
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.22334873
135cAMP signaling pathway_Homo sapiens_hsa040240.21363284
136Gap junction_Homo sapiens_hsa045400.19842609
137Non-homologous end-joining_Homo sapiens_hsa034500.19630457
138Oxytocin signaling pathway_Homo sapiens_hsa049210.18507183
139Glutamatergic synapse_Homo sapiens_hsa047240.16591717
140Taste transduction_Homo sapiens_hsa047420.16079431
141Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.15833365
142Cocaine addiction_Homo sapiens_hsa050300.15165188
143Proteasome_Homo sapiens_hsa030500.14979347
144Cell cycle_Homo sapiens_hsa041100.13373422
145Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.12236545
146HIF-1 signaling pathway_Homo sapiens_hsa040660.12048363
147Salmonella infection_Homo sapiens_hsa051320.11397989
148Epstein-Barr virus infection_Homo sapiens_hsa051690.09123946
149Sphingolipid metabolism_Homo sapiens_hsa006000.08156194
150Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.06528600
151RNA degradation_Homo sapiens_hsa030180.06233781

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