TEX9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.10030231
2cilium or flagellum-dependent cell motility (GO:0001539)4.86819040
3regulation of nuclear cell cycle DNA replication (GO:0033262)4.75960329
4neural tube formation (GO:0001841)4.69736354
5tryptophan catabolic process (GO:0006569)4.37466249
6indole-containing compound catabolic process (GO:0042436)4.37466249
7indolalkylamine catabolic process (GO:0046218)4.37466249
8protein localization to chromosome, centromeric region (GO:0071459)4.37404546
9indolalkylamine metabolic process (GO:0006586)4.34336849
10microtubule depolymerization (GO:0007019)4.27525141
11negative regulation of DNA-dependent DNA replication (GO:2000104)4.23064653
12acrosome assembly (GO:0001675)4.22694701
13axonemal dynein complex assembly (GO:0070286)4.21961523
14photoreceptor cell maintenance (GO:0045494)4.12207936
15CENP-A containing nucleosome assembly (GO:0034080)4.05584675
16regulation of centriole replication (GO:0046599)4.02134499
17kinetochore organization (GO:0051383)3.97463671
18kynurenine metabolic process (GO:0070189)3.96285833
19centriole replication (GO:0007099)3.95591001
20chromatin remodeling at centromere (GO:0031055)3.93299057
21detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.91257835
22tryptophan metabolic process (GO:0006568)3.82990673
23cilium morphogenesis (GO:0060271)3.82183338
24signal peptide processing (GO:0006465)3.82128396
25centriole assembly (GO:0098534)3.79748705
26cilium movement (GO:0003341)3.78411153
27monoubiquitinated protein deubiquitination (GO:0035520)3.74522003
28protein localization to chromosome (GO:0034502)3.65569255
29regulation of hippo signaling (GO:0035330)3.65486137
30protein K11-linked deubiquitination (GO:0035871)3.62048606
31histone exchange (GO:0043486)3.58323607
32epithelial cilium movement (GO:0003351)3.55657513
33left/right axis specification (GO:0070986)3.51532657
34kinetochore assembly (GO:0051382)3.51413862
35DNA replication-independent nucleosome organization (GO:0034724)3.46347829
36DNA replication-independent nucleosome assembly (GO:0006336)3.46347829
37regulation of histone H3-K27 methylation (GO:0061085)3.45852888
38male meiosis (GO:0007140)3.38766397
39protein K6-linked ubiquitination (GO:0085020)3.37830798
40detection of light stimulus involved in sensory perception (GO:0050962)3.37212649
41detection of light stimulus involved in visual perception (GO:0050908)3.37212649
42maturation of 5.8S rRNA (GO:0000460)3.36509736
43behavioral response to nicotine (GO:0035095)3.34356896
44cellular component assembly involved in morphogenesis (GO:0010927)3.33343766
45reflex (GO:0060004)3.27196076
46epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.25912998
47establishment of protein localization to Golgi (GO:0072600)3.25197936
48protein localization to cilium (GO:0061512)3.24229541
49behavioral response to ethanol (GO:0048149)3.24219664
50L-fucose metabolic process (GO:0042354)3.22122620
51L-fucose catabolic process (GO:0042355)3.22122620
52fucose catabolic process (GO:0019317)3.22122620
53replicative senescence (GO:0090399)3.21330863
54histone H2A acetylation (GO:0043968)3.21193973
55DNA ligation (GO:0006266)3.21015761
56interkinetic nuclear migration (GO:0022027)3.20391419
57telomere maintenance via telomerase (GO:0007004)3.19786120
58intraciliary transport (GO:0042073)3.19264175
59positive regulation of developmental pigmentation (GO:0048087)3.18448408
60retinal cone cell development (GO:0046549)3.18379495
61nonmotile primary cilium assembly (GO:0035058)3.17820842
62presynaptic membrane organization (GO:0097090)3.17534619
63motile cilium assembly (GO:0044458)3.15365666
64regulation of double-strand break repair via homologous recombination (GO:0010569)3.13683477
65sperm-egg recognition (GO:0035036)3.13569944
66spindle checkpoint (GO:0031577)3.13306579
67mitotic sister chromatid cohesion (GO:0007064)3.11916329
68negative regulation of DNA-templated transcription, elongation (GO:0032785)3.10674080
69negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.10674080
70positive regulation of histone H3-K4 methylation (GO:0051571)3.10299556
71telomere maintenance via semi-conservative replication (GO:0032201)3.10198575
72DNA strand elongation (GO:0022616)3.10158009
73multicellular organism reproduction (GO:0032504)3.08425048
74regulation of sarcomere organization (GO:0060297)3.07901828
75regulation of pigment cell differentiation (GO:0050932)3.07399102
76regulation of DNA endoreduplication (GO:0032875)3.07054034
77tachykinin receptor signaling pathway (GO:0007217)3.06262932
78benzene-containing compound metabolic process (GO:0042537)3.05695723
79intra-S DNA damage checkpoint (GO:0031573)3.05041262
80histone H3-K9 methylation (GO:0051567)3.03447881
81indole-containing compound metabolic process (GO:0042430)3.02731422
82cellular biogenic amine catabolic process (GO:0042402)3.02532086
83amine catabolic process (GO:0009310)3.02532086
84protein K48-linked deubiquitination (GO:0071108)3.02173187
85mitotic spindle checkpoint (GO:0071174)3.01445546
86DNA double-strand break processing (GO:0000729)3.00488214
87negative regulation of cytosolic calcium ion concentration (GO:0051481)2.98923416
88cellular ketone body metabolic process (GO:0046950)2.97306713
89telomere maintenance via recombination (GO:0000722)2.97181199
90regulation of cilium movement (GO:0003352)2.96395266
91mitotic recombination (GO:0006312)2.96146181
92DNA strand elongation involved in DNA replication (GO:0006271)2.94383952
93telomere maintenance via telomere lengthening (GO:0010833)2.92141634
94regulation of establishment of cell polarity (GO:2000114)2.91140464
95nuclear pore complex assembly (GO:0051292)2.89384548
96cell wall macromolecule catabolic process (GO:0016998)2.89357405
97cell wall macromolecule metabolic process (GO:0044036)2.89357405
98somatic hypermutation of immunoglobulin genes (GO:0016446)2.88574724
99somatic diversification of immune receptors via somatic mutation (GO:0002566)2.88574724
100regulation of meiosis I (GO:0060631)2.87947844
101metaphase plate congression (GO:0051310)2.87601365
102peptidyl-lysine trimethylation (GO:0018023)2.86742833
103double-strand break repair via homologous recombination (GO:0000724)2.85318683
104meiotic chromosome segregation (GO:0045132)2.85305519
105inner ear receptor stereocilium organization (GO:0060122)2.85056711
106prenylation (GO:0097354)2.84724554
107protein prenylation (GO:0018342)2.84724554
108regulation of posttranscriptional gene silencing (GO:0060147)2.84394704
109regulation of gene silencing by miRNA (GO:0060964)2.84394704
110regulation of gene silencing by RNA (GO:0060966)2.84394704
111recombinational repair (GO:0000725)2.83602712
112piRNA metabolic process (GO:0034587)2.83186718
113DNA replication initiation (GO:0006270)2.83002714
114mitotic metaphase plate congression (GO:0007080)2.82991017
115chromosome organization involved in meiosis (GO:0070192)2.82772379
116regulation of telomere maintenance via telomerase (GO:0032210)2.82682960
117regulation of collateral sprouting (GO:0048670)2.82322890
118axoneme assembly (GO:0035082)2.81366647
119protein K63-linked deubiquitination (GO:0070536)2.80807363
120protein polyglutamylation (GO:0018095)2.80460397
121cilium organization (GO:0044782)2.80178497
122mismatch repair (GO:0006298)2.80146377
123microtubule polymerization or depolymerization (GO:0031109)2.79762167
124mesenchymal cell differentiation involved in kidney development (GO:0072161)2.78605493
125mesenchymal cell differentiation involved in renal system development (GO:2001012)2.78605493
126RNA-dependent DNA replication (GO:0006278)2.75668666
127sulfation (GO:0051923)2.75641085
128cilium assembly (GO:0042384)2.74729935
129regulation of telomere maintenance (GO:0032204)2.73767832
130ventricular system development (GO:0021591)2.73531213
131reciprocal DNA recombination (GO:0035825)2.72825655
132reciprocal meiotic recombination (GO:0007131)2.72825655
133auditory receptor cell stereocilium organization (GO:0060088)2.72775516
134binding of sperm to zona pellucida (GO:0007339)2.72622027
135regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.72082206
136regulation of mitotic spindle checkpoint (GO:1903504)2.72082206
137ATP-dependent chromatin remodeling (GO:0043044)2.71830834
138cell-cell recognition (GO:0009988)2.70624465
139presynaptic membrane assembly (GO:0097105)2.69592270
140ketone body metabolic process (GO:1902224)2.67568120
141snRNA transcription (GO:0009301)2.66803059
142maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.66466679
143regulation of centrosome duplication (GO:0010824)2.66440950
144microtubule anchoring (GO:0034453)2.66438429
145cellular response to sterol (GO:0036315)2.65707239
146synaptonemal complex assembly (GO:0007130)2.64950565
147negative regulation of mast cell activation (GO:0033004)2.64406691
148DNA methylation involved in gamete generation (GO:0043046)2.64135025
149lymphoid progenitor cell differentiation (GO:0002320)2.64119131
150sperm motility (GO:0030317)2.63987672
151synapsis (GO:0007129)2.63817297
152microtubule bundle formation (GO:0001578)2.62821765
153telomere maintenance (GO:0000723)2.62674038
154replication fork processing (GO:0031297)2.62578111
155viral mRNA export from host cell nucleus (GO:0046784)2.61024672
156nucleotide-excision repair, DNA gap filling (GO:0006297)2.60864356
157synaptonemal complex organization (GO:0070193)2.59822051
158righting reflex (GO:0060013)2.59672267
159cellular response to gamma radiation (GO:0071480)2.59477081
160negative regulation of gene silencing (GO:0060969)2.58289075
161telomere organization (GO:0032200)2.57822399
162central nervous system neuron axonogenesis (GO:0021955)2.57290857
163thyroid hormone metabolic process (GO:0042403)2.56749549
164smoothened signaling pathway (GO:0007224)2.55666537
165gamma-aminobutyric acid transport (GO:0015812)2.55220792
166regulation of centrosome cycle (GO:0046605)2.54591376
167establishment of chromosome localization (GO:0051303)2.53745476
168positive regulation of histone methylation (GO:0031062)2.53577163
169cell projection assembly (GO:0030031)2.53055980
170negative regulation of mitotic sister chromatid separation (GO:2000816)2.53012282
171negative regulation of mitotic sister chromatid segregation (GO:0033048)2.53012282
172negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.53012282
173negative regulation of sister chromatid segregation (GO:0033046)2.53012282
174response to pheromone (GO:0019236)2.51714403
175serotonin metabolic process (GO:0042428)2.51620877
176transmission of nerve impulse (GO:0019226)2.49903477
177appendage development (GO:0048736)2.49846928
178limb development (GO:0060173)2.49846928
179photoreceptor cell development (GO:0042461)2.48509673
180detection of mechanical stimulus involved in sensory perception (GO:0050974)2.47638839
181regulation of establishment or maintenance of cell polarity (GO:0032878)2.47413942

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.62187232
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.56867025
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.20209086
4MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.03507827
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.94410479
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.87910811
7IGF1R_20145208_ChIP-Seq_DFB_Human2.85557805
8CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.75613350
9ZNF274_21170338_ChIP-Seq_K562_Hela2.63228280
10MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.52654568
11TP63_19390658_ChIP-ChIP_HaCaT_Human2.51331975
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.27078679
13AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.21388443
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.18022365
15POU5F1_16153702_ChIP-ChIP_HESCs_Human2.14508252
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.10500137
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.09762465
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.09718376
19PCGF2_27294783_Chip-Seq_ESCs_Mouse2.07542164
20FUS_26573619_Chip-Seq_HEK293_Human2.06462067
21SALL1_21062744_ChIP-ChIP_HESCs_Human2.05429898
22GBX2_23144817_ChIP-Seq_PC3_Human2.02653889
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.02606811
24RBPJ_22232070_ChIP-Seq_NCS_Mouse2.01351616
25PIAS1_25552417_ChIP-Seq_VCAP_Human1.92914203
26STAT3_23295773_ChIP-Seq_U87_Human1.92719214
27SMAD4_21799915_ChIP-Seq_A2780_Human1.92282818
28EWS_26573619_Chip-Seq_HEK293_Human1.91934605
29FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.89055329
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.82399064
31UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.79845641
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.79122133
33E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.78271589
34EST1_17652178_ChIP-ChIP_JURKAT_Human1.77633876
35PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.76367450
36* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.75747017
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.74950301
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.74850250
39TCF4_23295773_ChIP-Seq_U87_Human1.69952536
40BCAT_22108803_ChIP-Seq_LS180_Human1.69584884
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.67887984
42NR3C1_21868756_ChIP-Seq_MCF10A_Human1.65828705
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.65559283
44CBP_20019798_ChIP-Seq_JUKART_Human1.65559283
45PCGF2_27294783_Chip-Seq_NPCs_Mouse1.61656866
46RNF2_27304074_Chip-Seq_NSC_Mouse1.61370570
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60591481
48POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.60560202
49TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60560202
50TAF15_26573619_Chip-Seq_HEK293_Human1.59304632
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.58217242
52AR_25329375_ChIP-Seq_VCAP_Human1.57897917
53ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.54650449
54MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53544126
55* SMAD3_21741376_ChIP-Seq_EPCs_Human1.53157784
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.51151680
57SUZ12_27294783_Chip-Seq_NPCs_Mouse1.50725463
58SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.50537695
59NFE2_27457419_Chip-Seq_LIVER_Mouse1.47989414
60AR_21572438_ChIP-Seq_LNCaP_Human1.47720575
61TCF4_22108803_ChIP-Seq_LS180_Human1.45054550
62FOXP3_21729870_ChIP-Seq_TREG_Human1.43000271
63OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42982119
64NANOG_18555785_Chip-Seq_ESCs_Mouse1.40441417
65EZH2_22144423_ChIP-Seq_EOC_Human1.40084852
66EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.39061890
67EZH2_27294783_Chip-Seq_NPCs_Mouse1.38424743
68TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.37886642
69IRF1_19129219_ChIP-ChIP_H3396_Human1.36814462
70CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36193420
71CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.35827008
72RUNX2_22187159_ChIP-Seq_PCA_Human1.35108337
73AR_21909140_ChIP-Seq_LNCAP_Human1.34489508
74FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33607797
75JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.32758702
76MYC_18940864_ChIP-ChIP_HL60_Human1.32721158
77SUZ12_18555785_Chip-Seq_ESCs_Mouse1.31688910
78CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.31441927
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.31297118
80E2F1_18555785_Chip-Seq_ESCs_Mouse1.31083314
81P300_19829295_ChIP-Seq_ESCs_Human1.30971864
82* E2F1_21310950_ChIP-Seq_MCF-7_Human1.30366255
83OCT4_18555785_Chip-Seq_ESCs_Mouse1.29966893
84TP53_16413492_ChIP-PET_HCT116_Human1.29076120
85RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.28884469
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28461077
87MYC_18555785_ChIP-Seq_MESCs_Mouse1.28144922
88TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28079150
89KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27433098
90SMAD4_21741376_ChIP-Seq_EPCs_Human1.26758581
91SOX2_19829295_ChIP-Seq_ESCs_Human1.26502421
92NANOG_19829295_ChIP-Seq_ESCs_Human1.26502421
93NOTCH1_21737748_ChIP-Seq_TLL_Human1.26215641
94PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26199504
95* PRDM14_20953172_ChIP-Seq_ESCs_Human1.25389019
96CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.24377662
97FLI1_21867929_ChIP-Seq_TH2_Mouse1.24334946
98VDR_22108803_ChIP-Seq_LS180_Human1.24214646
99CDX2_22108803_ChIP-Seq_LS180_Human1.23897026
100STAT3_18555785_Chip-Seq_ESCs_Mouse1.23659971
101VDR_23849224_ChIP-Seq_CD4+_Human1.23523860
102EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.22954853
103HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.22786769
104FOXM1_26456572_ChIP-Seq_MCF-7_Human1.22631639
105CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21448766
106P53_22387025_ChIP-Seq_ESCs_Mouse1.21181761
107MYC_19030024_ChIP-ChIP_MESCs_Mouse1.20843194
108SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20466542
109P300_18555785_Chip-Seq_ESCs_Mouse1.20253144
110SRF_21415370_ChIP-Seq_HL-1_Mouse1.20029531
111CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19746664
112GATA1_26923725_Chip-Seq_HPCs_Mouse1.18634841
113NMYC_18555785_Chip-Seq_ESCs_Mouse1.18339718
114RUNX1_27457419_Chip-Seq_LIVER_Mouse1.17009465
115CMYC_18555785_Chip-Seq_ESCs_Mouse1.16655661
116TP53_22573176_ChIP-Seq_HFKS_Human1.15764524
117ARNT_22903824_ChIP-Seq_MCF-7_Human1.15326534
118BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.15154398
119SOX9_26525672_Chip-Seq_HEART_Mouse1.13965402
120EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10849463
121SOX2_21211035_ChIP-Seq_LN229_Gbm1.10828740
122SOX2_16153702_ChIP-ChIP_HESCs_Human1.10620797
123FOXA1_21572438_ChIP-Seq_LNCaP_Human1.10349813
124ZFX_18555785_Chip-Seq_ESCs_Mouse1.10326311
125TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10263197
126FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09850220
127BMI1_23680149_ChIP-Seq_NPCS_Mouse1.08965250
128ELK1_19687146_ChIP-ChIP_HELA_Human1.08555754
129AHR_22903824_ChIP-Seq_MCF-7_Human1.08512036
130OCT4_21477851_ChIP-Seq_ESCs_Mouse1.08289505
131TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07206221
132ESRRB_18555785_Chip-Seq_ESCs_Mouse1.07010977
133GABP_17652178_ChIP-ChIP_JURKAT_Human1.06951833
134CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.06082658
135TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.05777097
136SOX2_18555785_Chip-Seq_ESCs_Mouse1.03695455
137RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02317134
138ZNF217_24962896_ChIP-Seq_MCF-7_Human1.02238465
139ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.02129221
140KLF4_18555785_Chip-Seq_ESCs_Mouse1.01465118
141FOXA1_25329375_ChIP-Seq_VCAP_Human1.00759020
142FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00759020
143KDM2B_26808549_Chip-Seq_REH_Human1.00698895
144SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.99640084
145ER_23166858_ChIP-Seq_MCF-7_Human0.98569726
146TAL1_26923725_Chip-Seq_HPCs_Mouse0.98110857
147HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97821170
148CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.96794839
149CTBP1_25329375_ChIP-Seq_LNCAP_Human0.96656195
150EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.96475316
151CTCF_18555785_Chip-Seq_ESCs_Mouse0.96228006
152MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95400179
153PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94991981
154* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94841372
155CRX_20693478_ChIP-Seq_RETINA_Mouse0.93512751
156MYC_18358816_ChIP-ChIP_MESCs_Mouse0.93354063
157PU1_27457419_Chip-Seq_LIVER_Mouse0.91367744
158SMAD1_18555785_Chip-Seq_ESCs_Mouse0.91337507

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.61691786
2MP0000569_abnormal_digit_pigmentation3.98863689
3MP0006292_abnormal_olfactory_placode3.30581583
4MP0008058_abnormal_DNA_repair3.26579817
5MP0001188_hyperpigmentation3.23433605
6MP0003136_yellow_coat_color3.00698587
7MP0008877_abnormal_DNA_methylation2.94323876
8MP0003195_calcinosis2.84180873
9MP0010094_abnormal_chromosome_stability2.83466632
10MP0002009_preneoplasia2.62636174
11MP0003787_abnormal_imprinting2.53375075
12MP0005171_absent_coat_pigmentation2.40525021
13MP0000566_synostosis2.37381763
14MP0004043_abnormal_pH_regulation2.27345894
15MP0003111_abnormal_nucleus_morphology2.17076573
16MP0008007_abnormal_cellular_replicative2.15503054
17MP0002938_white_spotting2.10905558
18MP0003941_abnormal_skin_development2.09849771
19MP0002736_abnormal_nociception_after2.08050106
20MP0003646_muscle_fatigue2.04034012
21MP0001986_abnormal_taste_sensitivity2.03627973
22MP0005646_abnormal_pituitary_gland2.03145784
23MP0003121_genomic_imprinting2.02939972
24MP0009697_abnormal_copulation1.98697464
25MP0001968_abnormal_touch/_nociception1.91799207
26MP0003718_maternal_effect1.85702829
27MP0005410_abnormal_fertilization1.84569311
28MP0002396_abnormal_hematopoietic_system1.82083221
29MP0003077_abnormal_cell_cycle1.80490940
30MP0006276_abnormal_autonomic_nervous1.76188243
31MP0001501_abnormal_sleep_pattern1.64299948
32MP0002210_abnormal_sex_determination1.57624685
33MP0000049_abnormal_middle_ear1.55075436
34MP0003693_abnormal_embryo_hatching1.54593014
35MP0009745_abnormal_behavioral_response1.54381276
36MP0003786_premature_aging1.52690827
37MP0001929_abnormal_gametogenesis1.50302720
38MP0003698_abnormal_male_reproductive1.49673342
39MP0008872_abnormal_physiological_respon1.49451508
40MP0002735_abnormal_chemical_nociception1.41256264
41MP0010678_abnormal_skin_adnexa1.40579984
42MP0004142_abnormal_muscle_tone1.38127174
43MP0008932_abnormal_embryonic_tissue1.37414672
44MP0010386_abnormal_urinary_bladder1.36421608
45MP0002928_abnormal_bile_duct1.36342890
46MP0003252_abnormal_bile_duct1.35969165
47MP0004957_abnormal_blastocyst_morpholog1.35149403
48MP0009250_abnormal_appendicular_skeleto1.33809536
49MP0001145_abnormal_male_reproductive1.32097892
50MP0005409_darkened_coat_color1.30720764
51MP0001293_anophthalmia1.30023051
52MP0004133_heterotaxia1.29494755
53MP0002272_abnormal_nervous_system1.26896763
54MP0001529_abnormal_vocalization1.26433525
55MP0008995_early_reproductive_senescence1.24916764
56MP0002234_abnormal_pharynx_morphology1.24876526
57MP0005423_abnormal_somatic_nervous1.22949292
58MP0004147_increased_porphyrin_level1.22798955
59MP0002102_abnormal_ear_morphology1.22315591
60MP0002095_abnormal_skin_pigmentation1.20154509
61MP0005174_abnormal_tail_pigmentation1.20101088
62MP0000653_abnormal_sex_gland1.19934154
63MP0002638_abnormal_pupillary_reflex1.19299689
64MP0002249_abnormal_larynx_morphology1.18994351
65MP0003937_abnormal_limbs/digits/tail_de1.18807919
66MP0005395_other_phenotype1.18264868
67MP0003880_abnormal_central_pattern1.17700913
68MP0002837_dystrophic_cardiac_calcinosis1.16910255
69MP0003878_abnormal_ear_physiology1.14828587
70MP0005377_hearing/vestibular/ear_phenot1.14828587
71MP0005248_abnormal_Harderian_gland1.14252423
72MP0004134_abnormal_chest_morphology1.11491031
73MP0004215_abnormal_myocardial_fiber1.10865611
74MP0006054_spinal_hemorrhage1.10814787
75MP0000015_abnormal_ear_pigmentation1.10162615
76MP0008875_abnormal_xenobiotic_pharmacok1.09672575
77MP0003122_maternal_imprinting1.09022946
78MP0002572_abnormal_emotion/affect_behav1.08771736
79MP0000372_irregular_coat_pigmentation1.08659029
80MP0003950_abnormal_plasma_membrane1.07987371
81MP0006072_abnormal_retinal_apoptosis1.07723110
82MP0002067_abnormal_sensory_capabilities1.07554170
83MP0003315_abnormal_perineum_morphology1.07370896
84MP0005253_abnormal_eye_physiology1.06765363
85MP0000631_abnormal_neuroendocrine_gland1.04840810
86MP0005551_abnormal_eye_electrophysiolog1.04365821
87MP0004924_abnormal_behavior1.03699333
88MP0005386_behavior/neurological_phenoty1.03699333
89MP0008961_abnormal_basal_metabolism1.03512073
90MP0005085_abnormal_gallbladder_physiolo1.02735571
91MP0003123_paternal_imprinting1.02551197
92MP0003763_abnormal_thymus_physiology1.01948589
93MP0001119_abnormal_female_reproductive1.01735014
94MP0000490_abnormal_crypts_of1.01688726
95MP0010030_abnormal_orbit_morphology1.01507767
96MP0004145_abnormal_muscle_electrophysio1.00915357
97MP0001485_abnormal_pinna_reflex1.00299423
98MP0002160_abnormal_reproductive_system1.00221209
99MP0002116_abnormal_craniofacial_bone0.99315991
100MP0005195_abnormal_posterior_eye0.98370820
101MP0000647_abnormal_sebaceous_gland0.97554160
102MP0005645_abnormal_hypothalamus_physiol0.97499187
103MP0002064_seizures0.97412209
104MP0004885_abnormal_endolymph0.95780883
105MP0002168_other_aberrant_phenotype0.95292923
106MP0001970_abnormal_pain_threshold0.95122249
107MP0005310_abnormal_salivary_gland0.93740974
108MP0005499_abnormal_olfactory_system0.93697769
109MP0005394_taste/olfaction_phenotype0.93697769
110MP0002876_abnormal_thyroid_physiology0.92973976
111MP0003938_abnormal_ear_development0.92956310
112MP0002138_abnormal_hepatobiliary_system0.92085223
113MP0002653_abnormal_ependyma_morphology0.91977505
114MP0001324_abnormal_eye_pigmentation0.91604230
115MP0002751_abnormal_autonomic_nervous0.91148704
116MP0000230_abnormal_systemic_arterial0.91137068
117MP0005389_reproductive_system_phenotype0.90885918
118MP0000026_abnormal_inner_ear0.89857777
119MP0002229_neurodegeneration0.88898693
120MP0001486_abnormal_startle_reflex0.88645993
121MP0002752_abnormal_somatic_nervous0.88566931
122MP0001286_abnormal_eye_development0.88466467
123MP0003119_abnormal_digestive_system0.87725178
124MP0002090_abnormal_vision0.87626720
125MP0003045_fibrosis0.87098111
126MP0002132_abnormal_respiratory_system0.87086519
127MP0005075_abnormal_melanosome_morpholog0.85450119
128MP0005167_abnormal_blood-brain_barrier0.84912849
129MP0002733_abnormal_thermal_nociception0.84663192
130MP0005670_abnormal_white_adipose0.84132892
131MP0008789_abnormal_olfactory_epithelium0.83631174
132MP0003942_abnormal_urinary_system0.83149538
133MP0003385_abnormal_body_wall0.82555104
134MP0000432_abnormal_head_morphology0.80532369
135MP0005391_vision/eye_phenotype0.79632695
136MP0000428_abnormal_craniofacial_morphol0.77441944
137MP0000427_abnormal_hair_cycle0.75985710
138MP0002557_abnormal_social/conspecific_i0.75363434
139MP0009046_muscle_twitch0.75184784
140MP0001919_abnormal_reproductive_system0.74985315
141MP0003890_abnormal_embryonic-extraembry0.73980149
142MP0000537_abnormal_urethra_morphology0.73287587
143MP0002282_abnormal_trachea_morphology0.72992589
144MP0003011_delayed_dark_adaptation0.72795139
145MP0003861_abnormal_nervous_system0.71824741
146MP0003755_abnormal_palate_morphology0.71812625
147MP0003115_abnormal_respiratory_system0.70787359
148MP0001984_abnormal_olfaction0.70499980
149MP0002177_abnormal_outer_ear0.70491712
150MP0002109_abnormal_limb_morphology0.70423769
151MP0000778_abnormal_nervous_system0.69243059
152MP0001963_abnormal_hearing_physiology0.69192218
153MP0002114_abnormal_axial_skeleton0.68081812
154MP0000383_abnormal_hair_follicle0.66947950

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.43910845
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.25110440
3Chromsome breakage (HP:0040012)4.24368610
4Absent/shortened dynein arms (HP:0200106)3.94353363
5Dynein arm defect of respiratory motile cilia (HP:0012255)3.94353363
6Abnormal ciliary motility (HP:0012262)3.90551509
7Abnormal respiratory motile cilium physiology (HP:0012261)3.87834804
8Pancreatic fibrosis (HP:0100732)3.87001527
9Genetic anticipation (HP:0003743)3.62396241
10True hermaphroditism (HP:0010459)3.37955420
11Abnormal respiratory motile cilium morphology (HP:0005938)3.35063139
12Abnormal respiratory epithelium morphology (HP:0012253)3.35063139
13Gaze-evoked nystagmus (HP:0000640)3.33481273
14Progressive cerebellar ataxia (HP:0002073)3.13535118
15Median cleft lip (HP:0000161)3.05484025
16Occipital encephalocele (HP:0002085)3.03513177
17Hyperventilation (HP:0002883)3.02420334
18Rhinitis (HP:0012384)3.00882310
19Nephronophthisis (HP:0000090)2.96941226
20Volvulus (HP:0002580)2.88400498
21Pancreatic cysts (HP:0001737)2.78909066
2211 pairs of ribs (HP:0000878)2.74803612
23Embryonal renal neoplasm (HP:0011794)2.73729180
24Aplasia/Hypoplasia of the tibia (HP:0005772)2.70591014
25Attenuation of retinal blood vessels (HP:0007843)2.70136154
26Duplicated collecting system (HP:0000081)2.69423136
27Tubular atrophy (HP:0000092)2.67442611
28Preaxial hand polydactyly (HP:0001177)2.66064266
29Abnormality of the renal collecting system (HP:0004742)2.61400368
30Medial flaring of the eyebrow (HP:0010747)2.61147491
31Abnormality of the renal medulla (HP:0100957)2.55470298
32Tubulointerstitial nephritis (HP:0001970)2.53105489
33Renal dysplasia (HP:0000110)2.52045729
34Molar tooth sign on MRI (HP:0002419)2.50596364
35Abnormality of midbrain morphology (HP:0002418)2.50596364
36Chronic hepatic failure (HP:0100626)2.49831816
37Nephroblastoma (Wilms tumor) (HP:0002667)2.49777132
38Furrowed tongue (HP:0000221)2.46916297
39Fibular hypoplasia (HP:0003038)2.45132510
40Congenital stationary night blindness (HP:0007642)2.44867175
41Postaxial foot polydactyly (HP:0001830)2.41207444
42Optic nerve hypoplasia (HP:0000609)2.39544218
43Male pseudohermaphroditism (HP:0000037)2.39445351
44Abolished electroretinogram (ERG) (HP:0000550)2.37044698
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.36898743
46Meckel diverticulum (HP:0002245)2.32159657
47Facial cleft (HP:0002006)2.31284158
48Abnormal biliary tract physiology (HP:0012439)2.30772029
49Bile duct proliferation (HP:0001408)2.30772029
50Decreased circulating renin level (HP:0003351)2.30042848
51Stomach cancer (HP:0012126)2.28099994
52Central scotoma (HP:0000603)2.27715827
53Bony spicule pigmentary retinopathy (HP:0007737)2.26421656
54Abnormality of chromosome stability (HP:0003220)2.25834629
55Abnormality of the ileum (HP:0001549)2.23066815
56Abnormal number of incisors (HP:0011064)2.22482669
57Polydipsia (HP:0001959)2.21430212
58Abnormal drinking behavior (HP:0030082)2.21430212
59Fair hair (HP:0002286)2.20554551
60Medulloblastoma (HP:0002885)2.20328435
61Selective tooth agenesis (HP:0001592)2.20283398
62Supernumerary spleens (HP:0009799)2.17492432
63Absent speech (HP:0001344)2.16874608
64Abnormal lung lobation (HP:0002101)2.15216954
65Decreased central vision (HP:0007663)2.14552257
66Bell-shaped thorax (HP:0001591)2.13993963
67Aplasia/Hypoplasia of the uvula (HP:0010293)2.13926953
68Ectopic kidney (HP:0000086)2.13350412
69Renal cortical cysts (HP:0000803)2.12431337
70Birth length less than 3rd percentile (HP:0003561)2.11211959
71Congenital primary aphakia (HP:0007707)2.10782644
72Adrenal hypoplasia (HP:0000835)2.08923271
73Poor coordination (HP:0002370)2.08901286
74Febrile seizures (HP:0002373)2.05098301
75Congenital sensorineural hearing impairment (HP:0008527)2.04981479
76Abnormality of the preputium (HP:0100587)2.04746066
77Oculomotor apraxia (HP:0000657)2.04057823
78Colon cancer (HP:0003003)2.02786258
79Genital tract atresia (HP:0001827)2.02157907
80Type II lissencephaly (HP:0007260)2.02081180
81Aplasia/Hypoplasia of the fibula (HP:0006492)2.01157625
82Protruding tongue (HP:0010808)2.00235450
83Myelomeningocele (HP:0002475)1.99994796
84White forelock (HP:0002211)1.99608469
85Abnormality of the nasal septum (HP:0000419)1.99244637
86Congenital hepatic fibrosis (HP:0002612)1.99019400
87Gait imbalance (HP:0002141)1.98907583
88Embryonal neoplasm (HP:0002898)1.95372018
89Patchy hypopigmentation of hair (HP:0011365)1.95075910
90Chronic bronchitis (HP:0004469)1.93627757
91Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.93460079
92Cerebellar dysplasia (HP:0007033)1.93422364
93Nephrogenic diabetes insipidus (HP:0009806)1.93366873
94Sloping forehead (HP:0000340)1.88904421
95Broad-based gait (HP:0002136)1.88668281
96Anencephaly (HP:0002323)1.87354538
97Abnormality of the incisor (HP:0000676)1.86338017
98Abnormality of the renal cortex (HP:0011035)1.85909845
99Intestinal atresia (HP:0011100)1.85803714
100Missing ribs (HP:0000921)1.85591996
101Duodenal stenosis (HP:0100867)1.85347008
102Small intestinal stenosis (HP:0012848)1.85347008
103Abnormality of macular pigmentation (HP:0008002)1.84509713
104Cystic liver disease (HP:0006706)1.84376242
105Aganglionic megacolon (HP:0002251)1.84030141
106Aplasia/Hypoplasia of the sternum (HP:0006714)1.83303163
107Clubbing of toes (HP:0100760)1.83065401
108Midline defect of the nose (HP:0004122)1.82779603
109Bronchiectasis (HP:0002110)1.81400257
110Tubulointerstitial abnormality (HP:0001969)1.81350339
111Dialeptic seizures (HP:0011146)1.81310192
112Type I transferrin isoform profile (HP:0003642)1.81266550
113Impulsivity (HP:0100710)1.81236027
114Patellar aplasia (HP:0006443)1.81001404
115Vaginal atresia (HP:0000148)1.80760722
116Increased corneal curvature (HP:0100692)1.80334527
117Keratoconus (HP:0000563)1.80334527
118Astigmatism (HP:0000483)1.79591180
119Highly arched eyebrow (HP:0002553)1.76987765
120Dental crowding (HP:0000678)1.76798909
121Retinitis pigmentosa (HP:0000510)1.76468773
122Anophthalmia (HP:0000528)1.75908785
123Widely spaced teeth (HP:0000687)1.75805824
124Clumsiness (HP:0002312)1.75545246
125Dandy-Walker malformation (HP:0001305)1.75112778
126Postaxial hand polydactyly (HP:0001162)1.74918045
127Oligohydramnios (HP:0001562)1.74839293
128Chronic sinusitis (HP:0011109)1.74522763
129Prominent nasal bridge (HP:0000426)1.73521090
130Hypoplastic pelvis (HP:0008839)1.73445342
131Optic nerve coloboma (HP:0000588)1.73130783
132Short foot (HP:0001773)1.72630096
133Narrow forehead (HP:0000341)1.72618234
134Abnormality of the columella (HP:0009929)1.72133178
135Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.71406069
136Abnormality of alanine metabolism (HP:0010916)1.71406069
137Hyperalaninemia (HP:0003348)1.71406069
138Abnormality of the labia minora (HP:0012880)1.71363044
139Inability to walk (HP:0002540)1.71157309
140Abnormality of molar morphology (HP:0011070)1.70950670
141Abnormality of molar (HP:0011077)1.70950670
142Abnormality of permanent molar morphology (HP:0011071)1.70897096
143Abnormality of the dental root (HP:0006486)1.70897096
144Taurodontia (HP:0000679)1.70897096
145Bronchitis (HP:0012387)1.69777682
146Hypoplastic left heart (HP:0004383)1.69095482
147Scotoma (HP:0000575)1.67720302
148Abnormal rod and cone electroretinograms (HP:0008323)1.67318347
149Polyuria (HP:0000103)1.67315356
150Abnormality of the septum pellucidum (HP:0007375)1.67268369
151Small hand (HP:0200055)1.67080353
152Hypoplastic labia majora (HP:0000059)1.66316915
153Sclerocornea (HP:0000647)1.65286411
154Recurrent sinusitis (HP:0011108)1.64770992
155Absent septum pellucidum (HP:0001331)1.63392307
156Duplication of thumb phalanx (HP:0009942)1.63090856
157Aplasia/Hypoplasia of the earlobes (HP:0009906)1.62996059

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK8.41946239
2PLK43.90974445
3CASK2.80279066
4MKNK12.72205918
5ZAK2.70930332
6WEE12.57261736
7MKNK22.56790471
8VRK12.38818145
9SRPK12.38117072
10STK162.28608879
11CDC72.24156912
12MAP4K22.15634510
13MUSK2.14212668
14PNCK2.12150348
15AKT32.01378220
16BRSK22.00829483
17BRD41.91513747
18ATR1.83986034
19MAP3K41.83762940
20MAP2K71.80369937
21TNIK1.78966943
22YES11.68884353
23BUB11.66160410
24OXSR11.59587603
25ERBB31.57950193
26TTK1.52062569
27TAOK31.50809636
28IRAK41.46281621
29ACVR1B1.38353586
30TIE11.36595089
31CDK31.33762868
32PTK2B1.32986224
33BCR1.32749599
34PLK31.28809513
35STK31.26149964
36INSRR1.21170571
37LATS11.20637365
38SGK21.19944538
39CHEK21.18859049
40STK391.17384190
41TXK1.16827138
42TRIM281.16112939
43CDK71.15874263
44GRK11.15372767
45DYRK31.15293113
46IRAK31.14859672
47TEC1.14438886
48PINK11.13439487
49PBK1.12718774
50PLK11.11137322
51PLK21.08425330
52ADRBK21.08389887
53TSSK61.08131657
54CDK81.07393638
55EIF2AK31.06640260
56MAPK131.05063459
57CHEK11.01788649
58PIK3CG0.99648838
59EIF2AK20.97058812
60NTRK30.96969151
61PASK0.93411379
62ADRBK10.93081010
63ATM0.91301002
64AURKB0.87115557
65TLK10.86711543
66NEK60.86296359
67BMPR20.85907319
68SIK30.85687521
69MAPK150.85590229
70FER0.83251559
71CCNB10.80556289
72TGFBR10.80497844
73BRSK10.78864610
74STK38L0.73808106
75PAK30.71915138
76CSNK1A1L0.71604397
77CSNK1G20.71365869
78EIF2AK10.70520886
79MAPKAPK30.66849962
80IRAK10.66724998
81CDK10.65858446
82NEK20.63298808
83NUAK10.63236243
84CDK190.63167279
85AURKA0.61525801
86RPS6KB10.61506517
87NLK0.60826437
88CSNK1G10.60118417
89MARK30.59389790
90PRKCG0.59385314
91CSNK1G30.59105678
92MAP3K120.56824069
93IRAK20.56693479
94CLK10.56527221
95TNK20.56403567
96PRKAA20.55306020
97EPHA40.54881647
98CDK20.52444656
99FGFR20.52336729
100WNK40.52074491
101EPHA30.52057045
102PKN10.51917212
103PDK30.51356876
104PDK40.51356876
105MST40.51269715
106CSNK2A10.50682339
107ERBB20.49822758
108BMPR1B0.49650415
109SGK30.49387609
110CAMK2A0.48951559
111PRKCE0.48594614
112CAMKK20.47872442
113OBSCN0.45075850
114DAPK20.44817721
115PIM10.44037840
116SGK4940.43168876
117SGK2230.43168876
118CDK120.43055665
119DYRK1A0.42170599
120STK40.40595482
121PRKDC0.39650496
122FLT30.39542013
123MELK0.39521078
124MAPK140.39430366
125DYRK20.39298289
126WNK30.39253002
127GSK3B0.38666121
128CSNK1D0.37934879
129PRKAA10.36998309
130TRPM70.36944349
131PRKCI0.36879425
132CAMK1G0.36319459
133CSNK2A20.36310994
134RPS6KA50.35666150
135MARK10.34888514
136MAP3K70.33747060
137NTRK20.33636812
138PRKACA0.33042340
139TAF10.31382913
140PIK3CA0.31053365
141CDK40.30699808
142STK240.30630107
143KIT0.30627782
144PRKCQ0.30368667
145MAPKAPK50.30079149

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.79547305
2Mismatch repair_Homo sapiens_hsa034303.72666119
3Fanconi anemia pathway_Homo sapiens_hsa034603.58869611
4Homologous recombination_Homo sapiens_hsa034403.41234239
5Non-homologous end-joining_Homo sapiens_hsa034503.25812251
6RNA polymerase_Homo sapiens_hsa030202.90429697
7Butanoate metabolism_Homo sapiens_hsa006502.73780022
8Base excision repair_Homo sapiens_hsa034102.72484044
9Basal transcription factors_Homo sapiens_hsa030222.71640079
10Spliceosome_Homo sapiens_hsa030402.66391842
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.59138699
12Cell cycle_Homo sapiens_hsa041102.53996437
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.37338214
14Nucleotide excision repair_Homo sapiens_hsa034202.32345227
15RNA degradation_Homo sapiens_hsa030182.26044958
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.20073534
17Pyrimidine metabolism_Homo sapiens_hsa002402.15333945
18Nitrogen metabolism_Homo sapiens_hsa009102.13028733
19RNA transport_Homo sapiens_hsa030132.06738271
20ABC transporters_Homo sapiens_hsa020102.04603122
21Primary bile acid biosynthesis_Homo sapiens_hsa001202.02979336
22Tryptophan metabolism_Homo sapiens_hsa003802.02241960
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.90268743
24Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.87845009
25Steroid hormone biosynthesis_Homo sapiens_hsa001401.86324073
26Propanoate metabolism_Homo sapiens_hsa006401.83143758
27Phototransduction_Homo sapiens_hsa047441.74790197
28Purine metabolism_Homo sapiens_hsa002301.74408764
29mRNA surveillance pathway_Homo sapiens_hsa030151.65690267
30Basal cell carcinoma_Homo sapiens_hsa052171.62971504
31Chemical carcinogenesis_Homo sapiens_hsa052041.61682214
32Protein export_Homo sapiens_hsa030601.61470040
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.54813401
34beta-Alanine metabolism_Homo sapiens_hsa004101.51804809
35Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.48622037
36Retinol metabolism_Homo sapiens_hsa008301.42551374
37Caffeine metabolism_Homo sapiens_hsa002321.40560376
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.35826897
39Histidine metabolism_Homo sapiens_hsa003401.29807452
40Ribosome_Homo sapiens_hsa030101.29340358
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.26490401
42Proteasome_Homo sapiens_hsa030501.26293401
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.21192841
44Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.12846315
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12436798
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.11790441
47p53 signaling pathway_Homo sapiens_hsa041151.10689475
48Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.09865062
49Glycerolipid metabolism_Homo sapiens_hsa005611.08735697
50Circadian entrainment_Homo sapiens_hsa047131.08684204
51One carbon pool by folate_Homo sapiens_hsa006701.07430700
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.04276324
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.02644038
54Salivary secretion_Homo sapiens_hsa049701.01702537
55Wnt signaling pathway_Homo sapiens_hsa043101.01590127
56Primary immunodeficiency_Homo sapiens_hsa053401.00734372
57Circadian rhythm_Homo sapiens_hsa047100.97810113
58Nicotine addiction_Homo sapiens_hsa050330.97707156
59Maturity onset diabetes of the young_Homo sapiens_hsa049500.97341496
60Huntingtons disease_Homo sapiens_hsa050160.96845400
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.94639066
62Ether lipid metabolism_Homo sapiens_hsa005650.91296394
63Calcium signaling pathway_Homo sapiens_hsa040200.89413196
64Epstein-Barr virus infection_Homo sapiens_hsa051690.89296527
65Transcriptional misregulation in cancer_Homo sapiens_hsa052020.88300660
66Hedgehog signaling pathway_Homo sapiens_hsa043400.83166856
67Selenocompound metabolism_Homo sapiens_hsa004500.82743298
68Ovarian steroidogenesis_Homo sapiens_hsa049130.82285184
69Sphingolipid metabolism_Homo sapiens_hsa006000.81998303
70Peroxisome_Homo sapiens_hsa041460.81826748
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.81410433
72Herpes simplex infection_Homo sapiens_hsa051680.80826808
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78011092
74Fatty acid degradation_Homo sapiens_hsa000710.74530152
75Arachidonic acid metabolism_Homo sapiens_hsa005900.73571324
76Notch signaling pathway_Homo sapiens_hsa043300.72458045
77Pentose and glucuronate interconversions_Homo sapiens_hsa000400.70936506
78Taste transduction_Homo sapiens_hsa047420.70904924
79Dorso-ventral axis formation_Homo sapiens_hsa043200.70800409
80Renin-angiotensin system_Homo sapiens_hsa046140.70038837
81Vascular smooth muscle contraction_Homo sapiens_hsa042700.69753715
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.68692283
83HTLV-I infection_Homo sapiens_hsa051660.67725648
84Autoimmune thyroid disease_Homo sapiens_hsa053200.66139606
85Systemic lupus erythematosus_Homo sapiens_hsa053220.65805997
86Intestinal immune network for IgA production_Homo sapiens_hsa046720.63473945
87Alcoholism_Homo sapiens_hsa050340.62379484
88Fatty acid biosynthesis_Homo sapiens_hsa000610.62096205
89Lysine degradation_Homo sapiens_hsa003100.61237628
90Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60468804
91Hematopoietic cell lineage_Homo sapiens_hsa046400.58975778
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57534955
93Oocyte meiosis_Homo sapiens_hsa041140.55787361
94Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55708625
95N-Glycan biosynthesis_Homo sapiens_hsa005100.53418162
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52668300
97Viral carcinogenesis_Homo sapiens_hsa052030.52317299
98Long-term depression_Homo sapiens_hsa047300.49996555
99Pathways in cancer_Homo sapiens_hsa052000.49111078
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.48372920
101Measles_Homo sapiens_hsa051620.48306865
102Cysteine and methionine metabolism_Homo sapiens_hsa002700.48089383
103Hippo signaling pathway_Homo sapiens_hsa043900.47411287
104Glutathione metabolism_Homo sapiens_hsa004800.46245701
105Cholinergic synapse_Homo sapiens_hsa047250.45933592
106Asthma_Homo sapiens_hsa053100.44892302
107Morphine addiction_Homo sapiens_hsa050320.44598645
108Colorectal cancer_Homo sapiens_hsa052100.44486438
109Pentose phosphate pathway_Homo sapiens_hsa000300.44235447
110Linoleic acid metabolism_Homo sapiens_hsa005910.44107822
111Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43831365
112Dopaminergic synapse_Homo sapiens_hsa047280.42277624
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.42102016
114Steroid biosynthesis_Homo sapiens_hsa001000.41531320
115Melanoma_Homo sapiens_hsa052180.40363424
116MicroRNAs in cancer_Homo sapiens_hsa052060.38468952
117Prostate cancer_Homo sapiens_hsa052150.38146216
118Platelet activation_Homo sapiens_hsa046110.37846806
119alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37597570
120Pancreatic secretion_Homo sapiens_hsa049720.37020072
121Serotonergic synapse_Homo sapiens_hsa047260.36151655
122Oxytocin signaling pathway_Homo sapiens_hsa049210.35182560
123Other glycan degradation_Homo sapiens_hsa005110.34519005
124Glutamatergic synapse_Homo sapiens_hsa047240.33279991
125Regulation of autophagy_Homo sapiens_hsa041400.32920098
126Renin secretion_Homo sapiens_hsa049240.32312449
127Allograft rejection_Homo sapiens_hsa053300.32299509
128Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32141328
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.31391033
130Gastric acid secretion_Homo sapiens_hsa049710.30294895
131Melanogenesis_Homo sapiens_hsa049160.29007294
132Olfactory transduction_Homo sapiens_hsa047400.28220654
133TGF-beta signaling pathway_Homo sapiens_hsa043500.28059013
134Fat digestion and absorption_Homo sapiens_hsa049750.26867693
135Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.25413214
136Cocaine addiction_Homo sapiens_hsa050300.24905581
137Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.24487346
138Oxidative phosphorylation_Homo sapiens_hsa001900.22590504
139Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.20872449
140Metabolic pathways_Homo sapiens_hsa011000.20389751
141Type I diabetes mellitus_Homo sapiens_hsa049400.19128214
142cAMP signaling pathway_Homo sapiens_hsa040240.19056101
143Endometrial cancer_Homo sapiens_hsa052130.18936442
144Vitamin digestion and absorption_Homo sapiens_hsa049770.18847491
145Insulin secretion_Homo sapiens_hsa049110.17836604
146Sulfur metabolism_Homo sapiens_hsa009200.16794584
147PI3K-Akt signaling pathway_Homo sapiens_hsa041510.16581423
148GABAergic synapse_Homo sapiens_hsa047270.15733049

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