TFB2M

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1NADH metabolic process (GO:0006734)4.58163840
2proteasome assembly (GO:0043248)4.57739446
3nuclear pore complex assembly (GO:0051292)4.47737692
4lysine metabolic process (GO:0006553)4.43800218
5lysine catabolic process (GO:0006554)4.43800218
6serine family amino acid catabolic process (GO:0009071)4.35723134
7tricarboxylic acid cycle (GO:0006099)4.31843932
8biotin metabolic process (GO:0006768)4.30632853
9purine nucleobase biosynthetic process (GO:0009113)4.27645939
102-oxoglutarate metabolic process (GO:0006103)4.26938939
11glycine metabolic process (GO:0006544)4.22647926
12regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.20660316
13cellular ketone body metabolic process (GO:0046950)4.10499176
14pseudouridine synthesis (GO:0001522)4.06368351
15formation of translation preinitiation complex (GO:0001731)4.05679469
16nuclear pore organization (GO:0006999)4.02820067
17erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.00733156
18L-phenylalanine catabolic process (GO:0006559)4.00733156
19negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.99007974
20CENP-A containing nucleosome assembly (GO:0034080)3.98685745
21valine metabolic process (GO:0006573)3.94827823
22cysteine metabolic process (GO:0006534)3.93677648
23folic acid-containing compound biosynthetic process (GO:0009396)3.92193164
24establishment of integrated proviral latency (GO:0075713)3.92024096
25regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.91456556
26L-phenylalanine metabolic process (GO:0006558)3.88593650
27erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.88593650
28nucleobase biosynthetic process (GO:0046112)3.86767474
29ribosomal large subunit biogenesis (GO:0042273)3.84034854
30positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.83738586
31anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.81420794
32chromatin remodeling at centromere (GO:0031055)3.81386286
33branched-chain amino acid catabolic process (GO:0009083)3.80355077
34regulation of acyl-CoA biosynthetic process (GO:0050812)3.77926305
35IMP biosynthetic process (GO:0006188)3.77826540
36aromatic amino acid family catabolic process (GO:0009074)3.74612953
37carnitine shuttle (GO:0006853)3.73201992
38amino-acid betaine metabolic process (GO:0006577)3.68909554
39tryptophan catabolic process (GO:0006569)3.67339965
40indole-containing compound catabolic process (GO:0042436)3.67339965
41indolalkylamine catabolic process (GO:0046218)3.67339965
42fatty acid beta-oxidation (GO:0006635)3.66061740
43negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.65391267
44negative regulation of ligase activity (GO:0051352)3.65391267
45serine family amino acid metabolic process (GO:0009069)3.65335813
46kynurenine metabolic process (GO:0070189)3.63162324
47fatty acid transmembrane transport (GO:1902001)3.61770319
48* rRNA modification (GO:0000154)3.60420194
49tryptophan metabolic process (GO:0006568)3.58776348
50IMP metabolic process (GO:0046040)3.55326811
51sulfur amino acid catabolic process (GO:0000098)3.54742226
52glyoxylate metabolic process (GO:0046487)3.54359968
53tRNA aminoacylation for protein translation (GO:0006418)3.54143587
54DNA strand elongation involved in DNA replication (GO:0006271)3.53173107
55folic acid metabolic process (GO:0046655)3.50860096
56mitotic metaphase plate congression (GO:0007080)3.50434783
57regulation of cofactor metabolic process (GO:0051193)3.50341407
58regulation of coenzyme metabolic process (GO:0051196)3.50341407
59branched-chain amino acid metabolic process (GO:0009081)3.49988585
60tRNA aminoacylation (GO:0043039)3.48402120
61amino acid activation (GO:0043038)3.48402120
62ketone body metabolic process (GO:1902224)3.46886180
63ribonucleoprotein complex biogenesis (GO:0022613)3.46688771
64vitamin transmembrane transport (GO:0035461)3.46300486
65cullin deneddylation (GO:0010388)3.43187630
66establishment of viral latency (GO:0019043)3.42891179
67DNA strand elongation (GO:0022616)3.42208508
68DNA replication checkpoint (GO:0000076)3.39596371
69fatty acid oxidation (GO:0019395)3.37942199
70positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.37551910
71telomere maintenance via semi-conservative replication (GO:0032201)3.37131099
72serine family amino acid biosynthetic process (GO:0009070)3.36844836
73pore complex assembly (GO:0046931)3.34547680
74homocysteine metabolic process (GO:0050667)3.34091376
75* rRNA processing (GO:0006364)3.32289549
76histone exchange (GO:0043486)3.32231074
77protein deneddylation (GO:0000338)3.32212987
78establishment of protein localization to mitochondrial membrane (GO:0090151)3.32062732
79maturation of 5.8S rRNA (GO:0000460)3.31384019
80pteridine-containing compound biosynthetic process (GO:0042559)3.31140728
81positive regulation of ligase activity (GO:0051351)3.29534909
82regulation of cellular amino acid metabolic process (GO:0006521)3.28698094
83quinone biosynthetic process (GO:1901663)3.28558731
84ubiquinone biosynthetic process (GO:0006744)3.28558731
85fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.28469864
86lipid oxidation (GO:0034440)3.28005961
87signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.27909682
88signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.27909682
89signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.27909682
90DNA replication-independent nucleosome organization (GO:0034724)3.27830924
91DNA replication-independent nucleosome assembly (GO:0006336)3.27830924
92DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.27536809
93signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.27449942
94intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.27449942
95carnitine metabolic process (GO:0009437)3.25954262
96* mitochondrial RNA metabolic process (GO:0000959)3.25867726
97signal transduction involved in DNA integrity checkpoint (GO:0072401)3.22990316
98signal transduction involved in DNA damage checkpoint (GO:0072422)3.22990316
99transcription elongation from RNA polymerase III promoter (GO:0006385)3.22775366
100termination of RNA polymerase III transcription (GO:0006386)3.22775366
101mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.22662095
102oxaloacetate metabolic process (GO:0006107)3.22117786
103protein targeting to mitochondrion (GO:0006626)3.20065194
104urate metabolic process (GO:0046415)3.18519092
105regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.18298334
106short-chain fatty acid metabolic process (GO:0046459)3.16881591
107* rRNA metabolic process (GO:0016072)3.16852181
108transcription elongation from RNA polymerase I promoter (GO:0006362)3.15641537
109signal transduction involved in cell cycle checkpoint (GO:0072395)3.14930224
110mitotic nuclear envelope disassembly (GO:0007077)3.14519478
111regulation of ubiquitin-protein transferase activity (GO:0051438)3.14453865
112fatty acid catabolic process (GO:0009062)3.13456052
113alpha-amino acid catabolic process (GO:1901606)3.13104028
114double-strand break repair via nonhomologous end joining (GO:0006303)3.12420463
115non-recombinational repair (GO:0000726)3.12420463
116chaperone-mediated protein transport (GO:0072321)3.09908176
117regulation of sequestering of triglyceride (GO:0010889)3.09815590
118termination of RNA polymerase I transcription (GO:0006363)3.08941480
119regulation of mitotic spindle checkpoint (GO:1903504)3.08829175
120regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.08829175
121regulation of ligase activity (GO:0051340)3.08715016
122G1/S transition of mitotic cell cycle (GO:0000082)3.07544766
123cell cycle G1/S phase transition (GO:0044843)3.07544766
124* rRNA methylation (GO:0031167)3.07116082
125tricarboxylic acid metabolic process (GO:0072350)3.06428617
126succinate metabolic process (GO:0006105)3.06065454
127* transcription from mitochondrial promoter (GO:0006390)3.04668498
128exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.00632683
129spliceosomal snRNP assembly (GO:0000387)3.00221474
130cellular amino acid catabolic process (GO:0009063)2.99873529
131protein localization to kinetochore (GO:0034501)2.99843465
132bile acid biosynthetic process (GO:0006699)2.99680062
133histone mRNA metabolic process (GO:0008334)2.99219326
134telomere maintenance via recombination (GO:0000722)2.98758858
135regulation of translational fidelity (GO:0006450)2.98694506
136DNA replication-dependent nucleosome organization (GO:0034723)2.97536148
137DNA replication-dependent nucleosome assembly (GO:0006335)2.97536148
138protein localization to chromosome, centromeric region (GO:0071459)2.97037652
139aspartate family amino acid catabolic process (GO:0009068)2.96873343
140cellular component biogenesis (GO:0044085)2.96767460
141aromatic amino acid family metabolic process (GO:0009072)2.96524989
142DNA damage response, detection of DNA damage (GO:0042769)2.94611181
143regulation of sulfur metabolic process (GO:0042762)2.94562472
144regulation of mitochondrial translation (GO:0070129)2.93981904
145ribosome biogenesis (GO:0042254)2.93443694
146mitotic recombination (GO:0006312)2.93408471
147DNA catabolic process, exonucleolytic (GO:0000738)2.92976923
148DNA-templated transcription, termination (GO:0006353)2.92799964
149mitotic sister chromatid segregation (GO:0000070)2.92202601
150mitotic spindle checkpoint (GO:0071174)2.91648034
151protein localization to mitochondrion (GO:0070585)2.89929482
152regulation of spindle organization (GO:0090224)2.89864997
153spindle checkpoint (GO:0031577)2.89850214
154negative regulation of fatty acid biosynthetic process (GO:0045717)2.89146292
155sulfur amino acid metabolic process (GO:0000096)2.88667792
1567-methylguanosine mRNA capping (GO:0006370)2.87144961
157urea cycle (GO:0000050)2.86495137
158urea metabolic process (GO:0019627)2.86495137
159negative regulation of mitotic sister chromatid segregation (GO:0033048)2.86484163
160negative regulation of sister chromatid segregation (GO:0033046)2.86484163
161drug catabolic process (GO:0042737)2.86177683
162ethanol oxidation (GO:0006069)2.84943512
163pantothenate metabolic process (GO:0015939)2.82149478
164metaphase plate congression (GO:0051310)2.82138051
165organic acid catabolic process (GO:0016054)2.80808493
166carboxylic acid catabolic process (GO:0046395)2.80808493
167acetyl-CoA metabolic process (GO:0006084)2.80766978
168fructose metabolic process (GO:0006000)2.76859439
169monocarboxylic acid catabolic process (GO:0072329)2.76509036
170coenzyme catabolic process (GO:0009109)2.75222622
171ubiquinone metabolic process (GO:0006743)2.74168509
172alpha-linolenic acid metabolic process (GO:0036109)2.73743580
173nucleoside salvage (GO:0043174)2.73018966
174carnitine transmembrane transport (GO:1902603)2.72862962
175sulfur amino acid biosynthetic process (GO:0000097)2.72240569
176triglyceride homeostasis (GO:0070328)2.71868268
177acylglycerol homeostasis (GO:0055090)2.71868268
178S-adenosylmethionine metabolic process (GO:0046500)2.69506004
179fatty acid homeostasis (GO:0055089)2.69402688
180NAD metabolic process (GO:0019674)2.68931981
181regulation of protein activation cascade (GO:2000257)2.68801924
182regulation of triglyceride catabolic process (GO:0010896)2.68583337
183one-carbon metabolic process (GO:0006730)2.68120702
184amino-acid betaine transport (GO:0015838)2.67899274
185carnitine transport (GO:0015879)2.67899274
186pyrimidine-containing compound transmembrane transport (GO:0072531)2.64688616
187oxidative phosphorylation (GO:0006119)2.64331545
188nitrogen cycle metabolic process (GO:0071941)2.63020180
189DNA deamination (GO:0045006)2.62930328
190ribosome assembly (GO:0042255)2.62383269
191L-methionine salvage (GO:0071267)2.59978608
192L-methionine biosynthetic process (GO:0071265)2.59978608
193amino acid salvage (GO:0043102)2.59978608

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.00539189
2E2F7_22180533_ChIP-Seq_HELA_Human3.77664991
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.73422005
4RXR_22158963_ChIP-Seq_LIVER_Mouse3.49525930
5* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.44421128
6* PPARA_22158963_ChIP-Seq_LIVER_Mouse3.18875869
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.16162035
8* MYC_18555785_ChIP-Seq_MESCs_Mouse3.06015270
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.99597444
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.94397971
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.87648529
12CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.78054215
13* GABP_17652178_ChIP-ChIP_JURKAT_Human2.76960116
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.73824319
15EGR1_23403033_ChIP-Seq_LIVER_Mouse2.69947952
16CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.56037094
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.55955101
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.46050899
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.43337480
20LXR_22158963_ChIP-Seq_LIVER_Mouse2.34410872
21PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.25065989
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.23185393
23AR_21909140_ChIP-Seq_LNCAP_Human2.17319648
24* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.14007355
25E2F4_17652178_ChIP-ChIP_JURKAT_Human2.07705117
26* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.06554346
27NELFA_20434984_ChIP-Seq_ESCs_Mouse1.97303977
28VDR_23849224_ChIP-Seq_CD4+_Human1.96112953
29GATA1_22025678_ChIP-Seq_K562_Human1.92483537
30HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.89438776
31* SRF_21415370_ChIP-Seq_HL-1_Mouse1.86130632
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79224921
33CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.76267369
34FOXP3_21729870_ChIP-Seq_TREG_Human1.75155902
35DCP1A_22483619_ChIP-Seq_HELA_Human1.74317623
36FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.72347603
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71325097
38ZNF263_19887448_ChIP-Seq_K562_Human1.68053983
39* GABP_19822575_ChIP-Seq_HepG2_Human1.67383628
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.66902557
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.65924763
42CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.58565624
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57864124
44XRN2_22483619_ChIP-Seq_HELA_Human1.57068251
45NOTCH1_21737748_ChIP-Seq_TLL_Human1.56274370
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.55680669
47MYC_19079543_ChIP-ChIP_MESCs_Mouse1.54061876
48HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.53416522
49ZFX_18555785_ChIP-Seq_MESCs_Mouse1.51362206
50ELF1_17652178_ChIP-ChIP_JURKAT_Human1.50288774
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49629927
52CLOCK_20551151_ChIP-Seq_293T_Human1.49421497
53MYCN_18555785_ChIP-Seq_MESCs_Mouse1.49357018
54BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.42453461
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42365075
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.38458677
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.37588996
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.37533682
59STAT3_1855785_ChIP-Seq_MESCs_Mouse1.35766425
60ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.34668260
61ELK1_19687146_ChIP-ChIP_HELA_Human1.32352524
62KDM5A_27292631_Chip-Seq_BREAST_Human1.32110973
63KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.29222921
64HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.28837161
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27986100
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27483952
67SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.26737202
68CIITA_25753668_ChIP-Seq_RAJI_Human1.26215419
69MYC_18940864_ChIP-ChIP_HL60_Human1.26127414
70TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.23169043
71SALL1_21062744_ChIP-ChIP_HESCs_Human1.21870109
72NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.21459502
73STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.21174787
74* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20131628
75ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20125118
76SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15853705
77ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14865833
78KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13969027
79NANOG_18555785_ChIP-Seq_MESCs_Mouse1.10783575
80YY1_21170310_ChIP-Seq_MESCs_Mouse1.10169615
81SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.10130079
82FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.09885516
83MYC_22102868_ChIP-Seq_BL_Human1.07253102
84POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.06526713
85ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.05686976
86PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04558978
87SOX17_20123909_ChIP-Seq_XEN_Mouse1.04017390
88* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.01405371
89EGR1_19374776_ChIP-ChIP_THP-1_Human1.00924376
90CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95614319
91NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.92950493
92SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.92500246
93* GATA4_21415370_ChIP-Seq_HL-1_Mouse0.90599546
94CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.90119481
95ELF5_23300383_ChIP-Seq_T47D_Human0.88949642
96KAP1_22055183_ChIP-Seq_ESCs_Mouse0.88290002
97TTF2_22483619_ChIP-Seq_HELA_Human0.86799721
98CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85541615
99MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.84920854
100HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.82830705
101TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.82101658
102TFEB_21752829_ChIP-Seq_HELA_Human0.80563105
103* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.79779897
104POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.79749225
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.79689456
106ELK1_22589737_ChIP-Seq_MCF10A_Human0.78774451
107* NANOG_16153702_ChIP-ChIP_HESCs_Human0.78449289
108DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.77264212
109FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.77181949
110CHD1_26751641_Chip-Seq_LNCaP_Human0.77050041
111SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.76991323
112GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.76941298
113* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.76788128
114CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.76412520
115TBX5_21415370_ChIP-Seq_HL-1_Mouse0.75637429
116CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.75434270
117CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.74435838
118EWS_26573619_Chip-Seq_HEK293_Human0.73321156
119SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.67423151
120KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.67414030
121KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.67414030

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.79164058
2MP0005365_abnormal_bile_salt4.55073566
3MP0005360_urolithiasis4.31600447
4MP0005085_abnormal_gallbladder_physiolo3.92725858
5MP0003806_abnormal_nucleotide_metabolis3.38295429
6MP0003646_muscle_fatigue3.24755458
7MP0008875_abnormal_xenobiotic_pharmacok3.24632831
8MP0003693_abnormal_embryo_hatching3.05492571
9MP0008932_abnormal_embryonic_tissue2.87767452
10MP0006036_abnormal_mitochondrial_physio2.59890448
11MP0003941_abnormal_skin_development2.33497280
12MP0002837_dystrophic_cardiac_calcinosis2.28060448
13MP0003252_abnormal_bile_duct2.22105642
14MP0005332_abnormal_amino_acid2.18717394
15MP0003656_abnormal_erythrocyte_physiolo2.12021168
16MP0004084_abnormal_cardiac_muscle2.10617630
17MP0009840_abnormal_foam_cell2.06747079
18MP0009697_abnormal_copulation2.05942842
19MP0010329_abnormal_lipoprotein_level2.02727697
20MP0003221_abnormal_cardiomyocyte_apopto1.85217386
21MP0010234_abnormal_vibrissa_follicle1.84749689
22MP0003186_abnormal_redox_activity1.75366567
23MP0004957_abnormal_blastocyst_morpholog1.73958519
24MP0005319_abnormal_enzyme/_coenzyme1.71980611
25MP0000609_abnormal_liver_physiology1.71491230
26MP0004130_abnormal_muscle_cell1.66375628
27MP0004036_abnormal_muscle_relaxation1.65327894
28MP0006035_abnormal_mitochondrial_morpho1.65307192
29MP0002396_abnormal_hematopoietic_system1.64353375
30MP0003195_calcinosis1.56006257
31MP0003077_abnormal_cell_cycle1.55388735
32MP0005330_cardiomyopathy1.54220484
33MP0001764_abnormal_homeostasis1.53965499
34MP0005451_abnormal_body_composition1.51794548
35MP0004215_abnormal_myocardial_fiber1.48563504
36MP0003111_abnormal_nucleus_morphology1.46214850
37MP0001666_abnormal_nutrient_absorption1.45769138
38MP0008877_abnormal_DNA_methylation1.44867928
39MP0002877_abnormal_melanocyte_morpholog1.43521656
40MP0004147_increased_porphyrin_level1.42507077
41MP0002080_prenatal_lethality1.41265385
42MP0010094_abnormal_chromosome_stability1.41147428
43MP0000749_muscle_degeneration1.40852069
44MP0000313_abnormal_cell_death1.39068262
45MP0005220_abnormal_exocrine_pancreas1.38801355
46MP0002118_abnormal_lipid_homeostasis1.37164171
47MP0010352_gastrointestinal_tract_polyps1.36462996
48MP0009643_abnormal_urine_homeostasis1.35206806
49MP0000750_abnormal_muscle_regeneration1.34662790
50MP0005083_abnormal_biliary_tract1.33246902
51MP0000372_irregular_coat_pigmentation1.33086540
52MP0003950_abnormal_plasma_membrane1.30763288
53MP0003718_maternal_effect1.25918330
54MP0002269_muscular_atrophy1.25121688
55MP0005670_abnormal_white_adipose1.22529650
56MP0008057_abnormal_DNA_replication1.21997108
57MP0002160_abnormal_reproductive_system1.14440441
58MP0004019_abnormal_vitamin_homeostasis1.14068227
59MP0000598_abnormal_liver_morphology1.13949953
60MP0001929_abnormal_gametogenesis1.11428465
61MP0002086_abnormal_extraembryonic_tissu1.10760823
62MP0003191_abnormal_cellular_cholesterol1.10062010
63MP0002019_abnormal_tumor_incidence1.08779267
64MP0000751_myopathy1.08668952
65MP0004087_abnormal_muscle_fiber1.07697422
66MP0000747_muscle_weakness1.07074019
67MP0005636_abnormal_mineral_homeostasis1.06093838
68MP0008007_abnormal_cellular_replicative1.04724814
69MP0005266_abnormal_metabolism1.04167561
70MP0002210_abnormal_sex_determination1.03692757
71MP0005385_cardiovascular_system_phenoty1.02615826
72MP0001544_abnormal_cardiovascular_syste1.02615826
73MP0002085_abnormal_embryonic_tissue1.01912175
74MP0001853_heart_inflammation1.01348840
75MP0002106_abnormal_muscle_physiology1.01266766
76MP0009672_abnormal_birth_weight1.01195135
77MP0004233_abnormal_muscle_weight1.00907725
78MP0003868_abnormal_feces_composition1.00357946
79MP0004043_abnormal_pH_regulation0.99921675
80MP0008995_early_reproductive_senescence0.99448083
81MP0005501_abnormal_skin_physiology0.99133442
82MP0010630_abnormal_cardiac_muscle0.97405571
83MP0002084_abnormal_developmental_patter0.97105020
84MP0005584_abnormal_enzyme/coenzyme_acti0.96304093
85MP0001881_abnormal_mammary_gland0.95532961
86MP0002971_abnormal_brown_adipose0.95530768
87MP0005408_hypopigmentation0.94842358
88MP0002938_white_spotting0.94777094
89MP0002796_impaired_skin_barrier0.93827986
90MP0003890_abnormal_embryonic-extraembry0.93575559
91MP0001661_extended_life_span0.92085526
92MP0005666_abnormal_adipose_tissue0.91220910
93MP0001730_embryonic_growth_arrest0.90866112
94MP0001145_abnormal_male_reproductive0.88976892
95MP0005620_abnormal_muscle_contractility0.88928847
96MP0005395_other_phenotype0.87956807
97MP0004484_altered_response_of0.87571898
98MP0001756_abnormal_urination0.87195160
99MP0009333_abnormal_splenocyte_physiolog0.85510743
100MP0001545_abnormal_hematopoietic_system0.85508335
101MP0005397_hematopoietic_system_phenotyp0.85508335
102MP0005384_cellular_phenotype0.85087721
103MP0008058_abnormal_DNA_repair0.84560744
104MP0000653_abnormal_sex_gland0.84408696
105MP0003567_abnormal_fetal_cardiomyocyte0.84304739
106MP0004264_abnormal_extraembryonic_tissu0.84021454
107MP0002078_abnormal_glucose_homeostasis0.83672154
108MP0003943_abnormal_hepatobiliary_system0.82797928
109MP0003984_embryonic_growth_retardation0.82729200
110MP0002138_abnormal_hepatobiliary_system0.82672907
111MP0005084_abnormal_gallbladder_morpholo0.81274526
112MP0002060_abnormal_skin_morphology0.81074125
113MP0002972_abnormal_cardiac_muscle0.79997968
114MP0002088_abnormal_embryonic_growth/wei0.79761722
115MP0000490_abnormal_crypts_of0.79694122
116MP0001672_abnormal_embryogenesis/_devel0.79386382
117MP0005380_embryogenesis_phenotype0.79386382
118MP0004197_abnormal_fetal_growth/weight/0.77807106
119MP0006138_congestive_heart_failure0.77615927
120MP0000627_abnormal_mammary_gland0.76656329
121MP0005376_homeostasis/metabolism_phenot0.76429411
122MP0003315_abnormal_perineum_morphology0.75808787
123MP0004185_abnormal_adipocyte_glucose0.75290527
124MP0004808_abnormal_hematopoietic_stem0.74763636
125MP0001216_abnormal_epidermal_layer0.74570297
126MP0005075_abnormal_melanosome_morpholog0.74519825
127MP0001119_abnormal_female_reproductive0.74461862
128MP0005369_muscle_phenotype0.73770592
129MP0003828_pulmonary_edema0.71988850
130MP0010307_abnormal_tumor_latency0.70649460
131MP0009703_decreased_birth_body0.70159208
132MP0005621_abnormal_cell_physiology0.69538694
133MP0002006_tumorigenesis0.68366349
134MP0001697_abnormal_embryo_size0.68261880
135MP0005334_abnormal_fat_pad0.67646025
136MP0000350_abnormal_cell_proliferation0.66927937
137MP0003786_premature_aging0.66449159
138MP0000343_altered_response_to0.66444909
139MP0005379_endocrine/exocrine_gland_phen0.64928281
140MP0008469_abnormal_protein_level0.64795103
141MP0009763_increased_sensitivity_to0.63948009
142MP0009642_abnormal_blood_homeostasis0.63933541
143MP0008873_increased_physiological_sensi0.62796038
144MP0000358_abnormal_cell_content/0.62377064
145MP0003699_abnormal_female_reproductive0.62341885
146MP0005647_abnormal_sex_gland0.61868816
147MP0005389_reproductive_system_phenotype0.60621561
148MP0000516_abnormal_urinary_system0.59419280
149MP0005367_renal/urinary_system_phenotyp0.59419280
150MP0005410_abnormal_fertilization0.58996323
151MP0000703_abnormal_thymus_morphology0.58583815
152MP0002163_abnormal_gland_morphology0.57938731
153MP0006072_abnormal_retinal_apoptosis0.57368018
154MP0001727_abnormal_embryo_implantation0.56960259
155MP0001529_abnormal_vocalization0.54273697

Predicted human phenotypes

RankGene SetZ-score
1Hyperglycinemia (HP:0002154)5.21838875
2Hyperglycinuria (HP:0003108)5.11915191
3Abnormality of glycine metabolism (HP:0010895)4.50289802
4Abnormality of serine family amino acid metabolism (HP:0010894)4.50289802
5Hypoglycemic coma (HP:0001325)4.27992773
6Abnormality of fatty-acid metabolism (HP:0004359)3.89211591
7Abnormality of serum amino acid levels (HP:0003112)3.89206470
8Hyperammonemia (HP:0001987)3.87224973
9Gout (HP:0001997)3.73037978
10Microvesicular hepatic steatosis (HP:0001414)3.73032490
11Abnormality of aromatic amino acid family metabolism (HP:0004338)3.55498954
12Increased hepatocellular lipid droplets (HP:0006565)3.55064108
13Hyperalaninemia (HP:0003348)3.54654053
14Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.54654053
15Abnormality of alanine metabolism (HP:0010916)3.54654053
16Dicarboxylic aciduria (HP:0003215)3.54419843
17Abnormality of dicarboxylic acid metabolism (HP:0010995)3.54419843
18Intrahepatic cholestasis (HP:0001406)3.49218813
19Ketosis (HP:0001946)3.45644897
20Rhabdomyolysis (HP:0003201)3.43864675
21Chromsome breakage (HP:0040012)3.39306608
22Hypobetalipoproteinemia (HP:0003563)3.36488224
23Chromosomal breakage induced by crosslinking agents (HP:0003221)3.36122336
24Type I transferrin isoform profile (HP:0003642)3.34990751
25Hepatic necrosis (HP:0002605)3.28354859
26Degeneration of anterior horn cells (HP:0002398)3.25399206
27Abnormality of the anterior horn cell (HP:0006802)3.25399206
28Myoglobinuria (HP:0002913)3.22368420
29Aplastic anemia (HP:0001915)3.17616799
30Ketoacidosis (HP:0001993)3.10885674
31Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.09453910
32Lipid accumulation in hepatocytes (HP:0006561)3.07824202
33Reduced antithrombin III activity (HP:0001976)3.05077169
34Progressive macrocephaly (HP:0004481)3.02256636
35Proximal tubulopathy (HP:0000114)3.02102283
36Abnormality of monocarboxylic acid metabolism (HP:0010996)2.99854331
37Generalized aminoaciduria (HP:0002909)2.97610290
38Lethargy (HP:0001254)2.96452741
39Muscle fiber splitting (HP:0003555)2.88429207
40Hyperglycemia (HP:0003074)2.86203364
41Abnormality of the preputium (HP:0100587)2.85725579
42Cerebral edema (HP:0002181)2.81731058
43Metabolic acidosis (HP:0001942)2.77873382
44Hyperuricemia (HP:0002149)2.77698249
45Increased purine levels (HP:0004368)2.77698249
46Exercise-induced muscle cramps (HP:0003710)2.77671672
47Hypolipoproteinemia (HP:0010981)2.70389652
48Lactic acidosis (HP:0003128)2.69334650
49Abnormality of glycolysis (HP:0004366)2.66659161
50Increased serum pyruvate (HP:0003542)2.66659161
51Deep venous thrombosis (HP:0002625)2.65700009
52Abnormality of aspartate family amino acid metabolism (HP:0010899)2.64761630
53Abnormality of purine metabolism (HP:0004352)2.64504178
54Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.63080561
55Abnormal protein N-linked glycosylation (HP:0012347)2.63080561
56Abnormal protein glycosylation (HP:0012346)2.63080561
57Abnormal glycosylation (HP:0012345)2.63080561
58Xanthomatosis (HP:0000991)2.62970833
59Ragged-red muscle fibers (HP:0003200)2.62932854
60Nausea (HP:0002018)2.60683123
61Pancytopenia (HP:0001876)2.58381837
62Hyperlipoproteinemia (HP:0010980)2.58229789
63Increased intramyocellular lipid droplets (HP:0012240)2.57412717
64Exercise-induced myalgia (HP:0003738)2.56395818
65Abnormality of chromosome stability (HP:0003220)2.55815399
66Hepatocellular necrosis (HP:0001404)2.55378024
67Acute encephalopathy (HP:0006846)2.55038099
68Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.54603428
69Renal cortical cysts (HP:0000803)2.52587118
70Multiple enchondromatosis (HP:0005701)2.52005029
71Abnormality of the intrinsic pathway (HP:0010989)2.49227286
72Exercise intolerance (HP:0003546)2.47213094
73Decreased activity of mitochondrial respiratory chain (HP:0008972)2.46594106
74Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.46594106
75Rough bone trabeculation (HP:0100670)2.44788451
76Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.43889230
77Abnormality of methionine metabolism (HP:0010901)2.43467703
78Meckel diverticulum (HP:0002245)2.42575865
79Renal Fanconi syndrome (HP:0001994)2.42251529
80Impaired proprioception (HP:0010831)2.42115011
81Abnormality of sulfur amino acid metabolism (HP:0004339)2.40378318
82Hypoalphalipoproteinemia (HP:0003233)2.40143316
83Abnormality of nucleobase metabolism (HP:0010932)2.38114798
84Methylmalonic acidemia (HP:0002912)2.34994574
85Palpitations (HP:0001962)2.34445110
86Increased CSF lactate (HP:0002490)2.33739978
87Fat malabsorption (HP:0002630)2.32162653
88Increased serum lactate (HP:0002151)2.29827464
89Oral leukoplakia (HP:0002745)2.26777445
90Birth length less than 3rd percentile (HP:0003561)2.25929296
91Aplasia/Hypoplasia of the uvula (HP:0010293)2.25829532
92Myelodysplasia (HP:0002863)2.24383792
93Abnormal cartilage morphology (HP:0002763)2.23911418
94Limb hypertonia (HP:0002509)2.23409652
95Abnormality of the ileum (HP:0001549)2.22619546
96Small intestinal stenosis (HP:0012848)2.22301848
97Duodenal stenosis (HP:0100867)2.22301848
98Premature ovarian failure (HP:0008209)2.21515695
99CNS demyelination (HP:0007305)2.20152958
100Atrioventricular block (HP:0001678)2.19723715
101Sparse eyelashes (HP:0000653)2.16414452
102Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.15971121
103Megaloblastic anemia (HP:0001889)2.14325704
104Increased muscle lipid content (HP:0009058)2.13016617
105Trismus (HP:0000211)2.12174879
1063-Methylglutaconic aciduria (HP:0003535)2.10955134
107Progressive external ophthalmoplegia (HP:0000590)2.08747838
108Sensory axonal neuropathy (HP:0003390)2.06945250
109Abnormality of lateral ventricle (HP:0030047)2.05378541
110Hyperbilirubinemia (HP:0002904)2.04397487
111Muscle fiber inclusion bodies (HP:0100299)2.04266594
112Abnormality of glutamine family amino acid metabolism (HP:0010902)2.02660422
113Progressive muscle weakness (HP:0003323)2.02266020
114Neoplasm of the adrenal gland (HP:0100631)2.01963424
115Bundle branch block (HP:0011710)2.01350404
116Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.00797229
117Abnormal lung lobation (HP:0002101)1.99933072
118Secondary amenorrhea (HP:0000869)1.99336895
119Abnormal spermatogenesis (HP:0008669)1.99300867
120Methylmalonic aciduria (HP:0012120)1.98606807
121Respiratory difficulties (HP:0002880)1.97947370
122Abnormality of the common coagulation pathway (HP:0010990)1.97860293
123Cutaneous melanoma (HP:0012056)1.96450902
124Abnormal mitochondria in muscle tissue (HP:0008316)1.96203948
125Vomiting (HP:0002013)1.96067210
126Spastic paraparesis (HP:0002313)1.95096879
127Calf muscle hypertrophy (HP:0008981)1.94864459
128Carpal bone hypoplasia (HP:0001498)1.94051652
129Prolonged partial thromboplastin time (HP:0003645)1.92695032
130Hypokinesia (HP:0002375)1.92627408
131Macrocytic anemia (HP:0001972)1.92037208
132Abnormal trabecular bone morphology (HP:0100671)1.92021551
133Steatorrhea (HP:0002570)1.91815352
134Nemaline bodies (HP:0003798)1.91154092
135Abnormality of urine glucose concentration (HP:0011016)1.90304473
136Glycosuria (HP:0003076)1.90304473
137Insulin-resistant diabetes mellitus (HP:0000831)1.90021570
138Nephroblastoma (Wilms tumor) (HP:0002667)1.89708874
139Ileus (HP:0002595)1.87291192
140Lipoatrophy (HP:0100578)1.86612816
141Mitochondrial inheritance (HP:0001427)1.86395632
142Amniotic constriction ring (HP:0009775)1.85631238
143Abnormality of placental membranes (HP:0011409)1.85631238
144Abnormality of the duodenum (HP:0002246)1.85491587
145Abnormality of pyrimidine metabolism (HP:0004353)1.85336036
146Abnormality of the umbilical cord (HP:0010881)1.85054222
147Hepatocellular carcinoma (HP:0001402)1.84969797
148Irregular epiphyses (HP:0010582)1.84932986
149Entropion (HP:0000621)1.84563092
150Acute necrotizing encephalopathy (HP:0006965)1.83882676
151Respiratory failure (HP:0002878)1.83823040
152Reduced subcutaneous adipose tissue (HP:0003758)1.82674873
153Homocystinuria (HP:0002156)1.82028573
154Abnormality of homocysteine metabolism (HP:0010919)1.82028573
155Squamous cell carcinoma (HP:0002860)1.80474210
156Overlapping toe (HP:0001845)1.80436897
157Ventricular tachycardia (HP:0004756)1.80187387
158Abnormalities of placenta or umbilical cord (HP:0001194)1.79736024
159Conjunctival hamartoma (HP:0100780)1.76144432
160Horseshoe kidney (HP:0000085)1.76014171
161Absent thumb (HP:0009777)1.75158899
162Embryonal renal neoplasm (HP:0011794)1.73787604
163Leukodystrophy (HP:0002415)1.70396132
164Fatigue (HP:0012378)1.69493082
165Postnatal microcephaly (HP:0005484)1.69101862
166Hypergonadotropic hypogonadism (HP:0000815)1.68119595

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK14.93142943
2BCKDK4.49927546
3MST44.00764902
4EIF2AK13.72712693
5PBK3.23207477
6BUB12.65271143
7PDK42.61596600
8PDK32.61596600
9NEK22.60574263
10STK38L2.49553624
11BRSK22.44747141
12VRK22.28225630
13LATS12.15782150
14PDK22.14678117
15SCYL22.06291296
16WEE12.05784949
17FRK1.92018110
18PINK11.79585885
19MAP3K31.79239113
20EIF2AK31.77487038
21NEK91.76513834
22TAF11.73881246
23LMTK21.71077433
24ACVR1B1.66795265
25TTN1.60425192
26OBSCN1.49510480
27PLK41.48930915
28MAP2K31.42788506
29STK241.37541998
30NME21.37511360
31ZAK1.30606475
32TTK1.29464878
33PKN21.27797558
34DYRK31.27633499
35BRSK11.24197068
36MAP3K121.23720199
37FLT31.21807391
38MAP3K51.17328488
39EIF2AK21.17139285
40TRIM281.14955167
41ERN11.14711504
42IRAK31.12415320
43LATS21.11507851
44NUAK11.11263835
45PAK41.07482251
46CCNB11.06909012
47SRPK11.06464324
48AKT31.03808072
49STK161.02865608
50MST1R1.02050127
51PLK31.01998579
52AURKB1.01615290
53PLK10.98275083
54ERBB30.98263830
55INSRR0.96617970
56PRKAA10.95116419
57CDK80.94963534
58SIK10.93868144
59TRIB30.92692982
60ALK0.90078741
61PASK0.88451742
62RPS6KA40.86967079
63CDK40.86531942
64MYLK0.85577103
65FGFR40.84657154
66RAF10.84562232
67BCR0.83607374
68CDC70.83062030
69MAPK110.80839049
70STK30.80154227
71MAP3K60.79810543
72MKNK20.78656215
73CDK60.78544155
74ZAP700.75446281
75AURKA0.74557299
76TAOK10.74489977
77TAOK30.71654462
78MAP3K80.71406983
79BRAF0.71372410
80CHEK20.68859368
81PIK3CG0.68629251
82NME10.67839631
83ATM0.64613830
84CSNK2A20.64010389
85PRKAA20.62169294
86ERBB40.59729835
87ABL20.59111903
88FGFR30.58992319
89STK100.58383924
90CDK90.57722378
91MAP3K110.56872504
92BMPR20.56180019
93PIM20.55910539
94CAMKK20.55105826
95PRKCI0.53710496
96ATR0.51622536
97MAP4K10.50968418
98MET0.49491877
99MAPKAPK30.48623040
100EPHA20.48463048
101ARAF0.48393761
102MKNK10.47980504
103JAK10.47316623
104TSSK60.46664050
105SGK20.46229261
106PIM10.46093382
107STK40.45417437
108CLK10.44579785
109MARK30.43980099
110MAPK40.42735380
111TYK20.42577289
112LIMK10.41670987
113PIK3CA0.41031489
114MAP2K40.40965209
115MUSK0.40889220
116CDK10.40839568
117PRKG20.39669632
118CHEK10.38847669
119CDK70.37731152
120DAPK10.37290483
121CSNK1E0.36888104
122CDK20.36819860
123VRK10.36402736
124TEC0.35431078
125AKT20.33844783
126SIK30.33821249
127RPS6KA50.33707209
128PAK10.32778221
129TAOK20.32488366
130MAP3K90.31985037
131TNIK0.31851424
132MAPK120.31469437
133SGK30.31236945
134WNK30.30952018
135NEK60.30676408
136MELK0.29717593
137KDR0.29565339
138CDK30.28570120
139CSNK2A10.28053619
140CSNK1G10.27999133
141RPS6KB20.27989623
142BMPR1B0.27475550
143PAK20.26397247
144FGFR10.21616249
145PLK20.19616470
146TESK10.18526922
147CSNK1G30.18466447

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.31007539
2Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.14607392
3Propanoate metabolism_Homo sapiens_hsa006402.95932310
4Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.88408473
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.84864837
6Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.69073337
7Vitamin B6 metabolism_Homo sapiens_hsa007502.62308303
8Fatty acid degradation_Homo sapiens_hsa000712.61608292
9Ribosome_Homo sapiens_hsa030102.48463812
10Primary bile acid biosynthesis_Homo sapiens_hsa001202.47689478
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.14343299
12Carbon metabolism_Homo sapiens_hsa012002.14085054
13Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.08490181
14Butanoate metabolism_Homo sapiens_hsa006501.98338230
15Selenocompound metabolism_Homo sapiens_hsa004501.89821924
16Drug metabolism - other enzymes_Homo sapiens_hsa009831.88485485
17Tryptophan metabolism_Homo sapiens_hsa003801.87085552
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.85598147
19Fatty acid metabolism_Homo sapiens_hsa012121.83031672
20Biosynthesis of amino acids_Homo sapiens_hsa012301.78676271
21Pyruvate metabolism_Homo sapiens_hsa006201.76705554
22Arginine biosynthesis_Homo sapiens_hsa002201.75345162
23Peroxisome_Homo sapiens_hsa041461.70753154
24Cysteine and methionine metabolism_Homo sapiens_hsa002701.70642947
25RNA polymerase_Homo sapiens_hsa030201.65953220
26Fanconi anemia pathway_Homo sapiens_hsa034601.62666028
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.61571161
28Pentose and glucuronate interconversions_Homo sapiens_hsa000401.58391982
29Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.57511384
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.56101639
31beta-Alanine metabolism_Homo sapiens_hsa004101.53752072
32Caffeine metabolism_Homo sapiens_hsa002321.46800743
33Folate biosynthesis_Homo sapiens_hsa007901.45940714
34PPAR signaling pathway_Homo sapiens_hsa033201.38743868
35Sulfur metabolism_Homo sapiens_hsa009201.37804442
36Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.35498854
37Pentose phosphate pathway_Homo sapiens_hsa000301.33503430
38Pyrimidine metabolism_Homo sapiens_hsa002401.33223409
39Proteasome_Homo sapiens_hsa030501.30739003
40mRNA surveillance pathway_Homo sapiens_hsa030151.28831669
41Sulfur relay system_Homo sapiens_hsa041221.28477435
42Starch and sucrose metabolism_Homo sapiens_hsa005001.27995931
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.24481420
44RNA transport_Homo sapiens_hsa030131.23967455
45Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.21283983
46One carbon pool by folate_Homo sapiens_hsa006701.11325617
47Vitamin digestion and absorption_Homo sapiens_hsa049771.11095639
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.09906478
49Nitrogen metabolism_Homo sapiens_hsa009101.09333776
50Chemical carcinogenesis_Homo sapiens_hsa052041.04580300
51Complement and coagulation cascades_Homo sapiens_hsa046101.04472588
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99083746
53Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.98613369
54Phenylalanine metabolism_Homo sapiens_hsa003600.96864034
55Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.96409916
56Regulation of autophagy_Homo sapiens_hsa041400.90215981
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.89961746
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.89125990
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.88726372
60Fatty acid elongation_Homo sapiens_hsa000620.87784333
61Steroid hormone biosynthesis_Homo sapiens_hsa001400.86216780
62Cell cycle_Homo sapiens_hsa041100.84890028
63Maturity onset diabetes of the young_Homo sapiens_hsa049500.82588345
64Arginine and proline metabolism_Homo sapiens_hsa003300.82265339
65Tyrosine metabolism_Homo sapiens_hsa003500.81805591
66Steroid biosynthesis_Homo sapiens_hsa001000.81305754
67Retinol metabolism_Homo sapiens_hsa008300.79173161
68N-Glycan biosynthesis_Homo sapiens_hsa005100.78118161
69DNA replication_Homo sapiens_hsa030300.77808435
70Fructose and mannose metabolism_Homo sapiens_hsa000510.77113666
71RNA degradation_Homo sapiens_hsa030180.76838108
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.75708927
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74994052
74Parkinsons disease_Homo sapiens_hsa050120.74797857
75Glutathione metabolism_Homo sapiens_hsa004800.74089958
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.73326494
77Fat digestion and absorption_Homo sapiens_hsa049750.71735113
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.69943205
79Oocyte meiosis_Homo sapiens_hsa041140.69737711
80Metabolic pathways_Homo sapiens_hsa011000.69692765
81Purine metabolism_Homo sapiens_hsa002300.66906113
82Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66613668
83Galactose metabolism_Homo sapiens_hsa000520.65416354
84Lysine degradation_Homo sapiens_hsa003100.64340207
85Nucleotide excision repair_Homo sapiens_hsa034200.62801026
86Base excision repair_Homo sapiens_hsa034100.61630251
87Oxidative phosphorylation_Homo sapiens_hsa001900.60125180
88Epstein-Barr virus infection_Homo sapiens_hsa051690.59883459
89p53 signaling pathway_Homo sapiens_hsa041150.58909651
90Basal transcription factors_Homo sapiens_hsa030220.58677363
91Bile secretion_Homo sapiens_hsa049760.53142406
92Histidine metabolism_Homo sapiens_hsa003400.52792771
93Glycerolipid metabolism_Homo sapiens_hsa005610.51790563
94Protein export_Homo sapiens_hsa030600.50968049
95Legionellosis_Homo sapiens_hsa051340.50256950
96Huntingtons disease_Homo sapiens_hsa050160.50082991
97ABC transporters_Homo sapiens_hsa020100.49698492
98Mismatch repair_Homo sapiens_hsa034300.49660817
99Non-homologous end-joining_Homo sapiens_hsa034500.47789313
100Spliceosome_Homo sapiens_hsa030400.47569896
101Insulin resistance_Homo sapiens_hsa049310.47401100
102Circadian rhythm_Homo sapiens_hsa047100.46161869
103Homologous recombination_Homo sapiens_hsa034400.44469046
104Thyroid cancer_Homo sapiens_hsa052160.43348876
105Systemic lupus erythematosus_Homo sapiens_hsa053220.41770915
106Viral carcinogenesis_Homo sapiens_hsa052030.35629496
107AMPK signaling pathway_Homo sapiens_hsa041520.32049152
108Glucagon signaling pathway_Homo sapiens_hsa049220.31434304
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30724004
110Staphylococcus aureus infection_Homo sapiens_hsa051500.29727677
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.29680064
112Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.29579179
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.22819624
114Herpes simplex infection_Homo sapiens_hsa051680.21602944
115Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.21374652
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.20771082
117Alzheimers disease_Homo sapiens_hsa050100.20564838
118TGF-beta signaling pathway_Homo sapiens_hsa043500.20552435
119Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.16157893
120Shigellosis_Homo sapiens_hsa051310.12846815
121Alcoholism_Homo sapiens_hsa050340.09384496
122SNARE interactions in vesicular transport_Homo sapiens_hsa041300.07211610
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.07153205

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