Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.46559226 |
2 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.71487797 |
3 | maturation of SSU-rRNA (GO:0030490) | 4.67989234 |
4 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.58767770 |
5 | formation of translation preinitiation complex (GO:0001731) | 4.52707912 |
6 | DNA strand elongation (GO:0022616) | 4.51463542 |
7 | DNA replication initiation (GO:0006270) | 4.34497772 |
8 | DNA deamination (GO:0045006) | 4.23882439 |
9 | ribosomal small subunit biogenesis (GO:0042274) | 4.17192711 |
10 | DNA replication checkpoint (GO:0000076) | 4.09509008 |
11 | telomere maintenance via recombination (GO:0000722) | 4.05732938 |
12 | viral transcription (GO:0019083) | 3.96588587 |
13 | nucleobase biosynthetic process (GO:0046112) | 3.95863430 |
14 | ribosomal large subunit biogenesis (GO:0042273) | 3.91836016 |
15 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.91769824 |
16 | translational termination (GO:0006415) | 3.89041830 |
17 | establishment of integrated proviral latency (GO:0075713) | 3.88411955 |
18 | protein localization to kinetochore (GO:0034501) | 3.88385433 |
19 | ribosome biogenesis (GO:0042254) | 3.87741310 |
20 | purine nucleobase biosynthetic process (GO:0009113) | 3.82831077 |
21 | CENP-A containing nucleosome assembly (GO:0034080) | 3.82592063 |
22 | IMP biosynthetic process (GO:0006188) | 3.81519139 |
23 | DNA unwinding involved in DNA replication (GO:0006268) | 3.81514972 |
24 | mitotic metaphase plate congression (GO:0007080) | 3.80290301 |
25 | mitotic recombination (GO:0006312) | 3.79854540 |
26 | regulation of mitochondrial translation (GO:0070129) | 3.74111166 |
27 | chromatin remodeling at centromere (GO:0031055) | 3.72273178 |
28 | proteasome assembly (GO:0043248) | 3.69267006 |
29 | telomere maintenance via telomere lengthening (GO:0010833) | 3.65230060 |
30 | translational elongation (GO:0006414) | 3.60857482 |
31 | protein maturation by protein folding (GO:0022417) | 3.55786388 |
32 | translational initiation (GO:0006413) | 3.55212556 |
33 | ribosome assembly (GO:0042255) | 3.53690953 |
34 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.51530935 |
35 | spliceosomal snRNP assembly (GO:0000387) | 3.51169527 |
36 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.49487059 |
37 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.43279695 |
38 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.42811754 |
39 | establishment of viral latency (GO:0019043) | 3.41704093 |
40 | rRNA processing (GO:0006364) | 3.39808846 |
41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.37287901 |
42 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.36627571 |
43 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.36627571 |
44 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.35887052 |
45 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.35556785 |
46 | DNA replication-independent nucleosome organization (GO:0034724) | 3.35556785 |
47 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.35257469 |
48 | kinetochore organization (GO:0051383) | 3.35236432 |
49 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.34656040 |
50 | metaphase plate congression (GO:0051310) | 3.34192548 |
51 | IMP metabolic process (GO:0046040) | 3.33934181 |
52 | pentose-phosphate shunt (GO:0006098) | 3.33537429 |
53 | cotranslational protein targeting to membrane (GO:0006613) | 3.33092423 |
54 | protein localization to chromosome, centromeric region (GO:0071459) | 3.32171136 |
55 | protein targeting to ER (GO:0045047) | 3.31828687 |
56 | negative regulation of B cell apoptotic process (GO:0002903) | 3.31023489 |
57 | proline biosynthetic process (GO:0006561) | 3.30288913 |
58 | kinetochore assembly (GO:0051382) | 3.28275310 |
59 | * viral mRNA export from host cell nucleus (GO:0046784) | 3.27643968 |
60 | rRNA metabolic process (GO:0016072) | 3.27073244 |
61 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.26884096 |
62 | mitotic nuclear envelope disassembly (GO:0007077) | 3.26067042 |
63 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.24950314 |
64 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.24748663 |
65 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.24583224 |
66 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.23408155 |
67 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.23408155 |
68 | purine nucleotide salvage (GO:0032261) | 3.22472105 |
69 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.22261804 |
70 | negative regulation of ligase activity (GO:0051352) | 3.19122231 |
71 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.19122231 |
72 | regulation of translational termination (GO:0006449) | 3.18878592 |
73 | rRNA modification (GO:0000154) | 3.18498733 |
74 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.18498531 |
75 | nucleotide salvage (GO:0043173) | 3.17999337 |
76 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.17668210 |
77 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.15419635 |
78 | metallo-sulfur cluster assembly (GO:0031163) | 3.14292304 |
79 | iron-sulfur cluster assembly (GO:0016226) | 3.14292304 |
80 | protein localization to endoplasmic reticulum (GO:0070972) | 3.13706482 |
81 | translation (GO:0006412) | 3.12342418 |
82 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.11493245 |
83 | pseudouridine synthesis (GO:0001522) | 3.10885462 |
84 | NADPH regeneration (GO:0006740) | 3.10769950 |
85 | establishment of chromosome localization (GO:0051303) | 3.10549059 |
86 | viral life cycle (GO:0019058) | 3.10360863 |
87 | cellular protein complex disassembly (GO:0043624) | 3.05918822 |
88 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.05835902 |
89 | cell cycle G1/S phase transition (GO:0044843) | 3.05835902 |
90 | deoxyribonucleotide catabolic process (GO:0009264) | 3.05295358 |
91 | histone arginine methylation (GO:0034969) | 3.03863200 |
92 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.02666082 |
93 | deoxyribose phosphate catabolic process (GO:0046386) | 3.02198567 |
94 | tRNA methylation (GO:0030488) | 3.01857643 |
95 | histone exchange (GO:0043486) | 2.99778051 |
96 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.98809282 |
97 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.98809282 |
98 | nuclear envelope disassembly (GO:0051081) | 2.98671084 |
99 | membrane disassembly (GO:0030397) | 2.98671084 |
100 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.98631246 |
101 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.98631246 |
102 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.98631246 |
103 | nuclear envelope reassembly (GO:0031468) | 2.97715517 |
104 | mitotic nuclear envelope reassembly (GO:0007084) | 2.97715517 |
105 | cellular component biogenesis (GO:0044085) | 2.96993133 |
106 | negative regulation of mRNA processing (GO:0050686) | 2.95561655 |
107 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.93010548 |
108 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.93010548 |
109 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.91030087 |
110 | protein K6-linked ubiquitination (GO:0085020) | 2.90972319 |
111 | glucose catabolic process (GO:0006007) | 2.90394874 |
112 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.89224049 |
113 | base-excision repair (GO:0006284) | 2.89080279 |
114 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.88904036 |
115 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.88872388 |
116 | termination of RNA polymerase III transcription (GO:0006386) | 2.87127978 |
117 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.87127978 |
118 | regulation of spindle organization (GO:0090224) | 2.87113057 |
119 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.86367714 |
120 | 7-methylguanosine mRNA capping (GO:0006370) | 2.86001290 |
121 | mismatch repair (GO:0006298) | 2.85777956 |
122 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.85514847 |
123 | spliceosomal complex assembly (GO:0000245) | 2.84702433 |
124 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.84569715 |
125 | telomere organization (GO:0032200) | 2.83628693 |
126 | RNA capping (GO:0036260) | 2.83012629 |
127 | 7-methylguanosine RNA capping (GO:0009452) | 2.83012629 |
128 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.82792567 |
129 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.80926672 |
130 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.80575427 |
131 | pentose metabolic process (GO:0019321) | 2.79707286 |
132 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.78621452 |
133 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.77855420 |
134 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.77641177 |
135 | rRNA transcription (GO:0009303) | 2.74179089 |
136 | pinocytosis (GO:0006907) | 2.73648051 |
137 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.73018826 |
138 | DNA ligation (GO:0006266) | 2.71879860 |
139 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.68435747 |
140 | peptidyl-arginine methylation (GO:0018216) | 2.66483044 |
141 | peptidyl-arginine N-methylation (GO:0035246) | 2.66483044 |
142 | positive regulation of ligase activity (GO:0051351) | 2.65266238 |
143 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.64697004 |
144 | mitochondrial RNA metabolic process (GO:0000959) | 2.64502282 |
145 | negative regulation of RNA splicing (GO:0033119) | 2.64446168 |
146 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.64211747 |
147 | negative regulation of mRNA metabolic process (GO:1903312) | 2.64203631 |
148 | GDP-mannose metabolic process (GO:0019673) | 2.62237726 |
149 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.62077467 |
150 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.61880491 |
151 | nucleoside salvage (GO:0043174) | 2.61176736 |
152 | base-excision repair, AP site formation (GO:0006285) | 2.60094171 |
153 | mitochondrial calcium ion transport (GO:0006851) | 2.55040748 |
154 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.54603358 |
155 | regulation of translational fidelity (GO:0006450) | 2.53998119 |
156 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.51942330 |
157 | regulation of B cell apoptotic process (GO:0002902) | 2.48883705 |
158 | regulation of ligase activity (GO:0051340) | 2.47278254 |
159 | CTP metabolic process (GO:0046036) | 2.45822632 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.73955191 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.20774900 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.70696937 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.37478401 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.32236321 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.25239674 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.23015621 |
8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.00525700 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.98693633 |
10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.98156769 |
11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.91840880 |
12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.89507864 |
13 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.86174934 |
14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.84193426 |
15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.74113999 |
16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.64643373 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.59723265 |
18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.32885959 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.32090823 |
20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.29413545 |
21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.27620353 |
22 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.26037436 |
23 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.08120078 |
24 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.02934395 |
25 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.02437990 |
26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.00785228 |
27 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.92200551 |
28 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.91508162 |
29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.89201034 |
30 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.88838427 |
31 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.88019371 |
32 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.87102373 |
33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.78294864 |
34 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.78151155 |
35 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.77843754 |
36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74716983 |
37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.72988996 |
38 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.70042345 |
39 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.69042755 |
40 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.68916485 |
41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.68822088 |
42 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.66159614 |
43 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.65436349 |
44 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65029203 |
45 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.59896071 |
46 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.59597533 |
47 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.59361104 |
48 | * TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.59027604 |
49 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.58845873 |
50 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.57872549 |
51 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.55506500 |
52 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.51184829 |
53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.50233531 |
54 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.49743991 |
55 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.48130009 |
56 | MYC_22102868_ChIP-Seq_BL_Human | 1.47846422 |
57 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45649153 |
58 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.43527420 |
59 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.40758311 |
60 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.38863134 |
61 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36980222 |
62 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.33147916 |
63 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.32167692 |
64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.32066168 |
65 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.30617928 |
66 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.29607430 |
67 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.29067128 |
68 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.28868506 |
69 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.28856129 |
70 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.25754822 |
71 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.24647989 |
72 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.24306143 |
73 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.23980219 |
74 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.23409723 |
75 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.22989507 |
76 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.22795994 |
77 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.20286641 |
78 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.17503815 |
79 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.16242054 |
80 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15841028 |
81 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14875594 |
82 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.13121932 |
83 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.12697376 |
84 | * MAF_26560356_Chip-Seq_TH1_Human | 1.12652391 |
85 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.12036702 |
86 | UTX_26944678_Chip-Seq_JUKART_Human | 1.11873425 |
87 | P68_20966046_ChIP-Seq_HELA_Human | 1.11569413 |
88 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.09768106 |
89 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.08995530 |
90 | MAF_26560356_Chip-Seq_TH2_Human | 1.08538263 |
91 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.07763169 |
92 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.07763169 |
93 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.07763169 |
94 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.07664615 |
95 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07330498 |
96 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07237808 |
97 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.05012402 |
98 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04145996 |
99 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.03832013 |
100 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.03133574 |
101 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.02084956 |
102 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.02010179 |
103 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.01461370 |
104 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.01288670 |
105 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.01179570 |
106 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.01168439 |
107 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.00425822 |
108 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.99974788 |
109 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.99875235 |
110 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.99201599 |
111 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.99130738 |
112 | * NCOR1_26117541_ChIP-Seq_K562_Human | 0.98378327 |
113 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98371620 |
114 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.95141725 |
115 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.94788641 |
116 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.93591513 |
117 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.93195845 |
118 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.92660677 |
119 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90647884 |
120 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.87058050 |
121 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.86727548 |
122 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.85446166 |
123 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.84074643 |
124 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.82925071 |
125 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.81309635 |
126 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.80074662 |
127 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.79459813 |
128 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.77673393 |
129 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.77154993 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.65305454 |
2 | MP0010094_abnormal_chromosome_stability | 4.51928526 |
3 | MP0003111_abnormal_nucleus_morphology | 4.38574617 |
4 | MP0004957_abnormal_blastocyst_morpholog | 4.35121686 |
5 | MP0003077_abnormal_cell_cycle | 3.89594126 |
6 | MP0008057_abnormal_DNA_replication | 3.38265052 |
7 | MP0008058_abnormal_DNA_repair | 3.23327581 |
8 | MP0008007_abnormal_cellular_replicative | 2.82928829 |
9 | MP0005058_abnormal_lysosome_morphology | 2.66119607 |
10 | MP0008932_abnormal_embryonic_tissue | 2.57404907 |
11 | MP0002396_abnormal_hematopoietic_system | 2.45595591 |
12 | MP0005451_abnormal_body_composition | 2.20796529 |
13 | MP0003786_premature_aging | 2.07162142 |
14 | MP0001730_embryonic_growth_arrest | 2.06887461 |
15 | MP0000350_abnormal_cell_proliferation | 2.05687927 |
16 | MP0008877_abnormal_DNA_methylation | 2.02476189 |
17 | MP0002254_reproductive_system_inflammat | 1.94839599 |
18 | MP0009840_abnormal_foam_cell | 1.90732568 |
19 | MP0003718_maternal_effect | 1.86159954 |
20 | MP0003806_abnormal_nucleotide_metabolis | 1.83898108 |
21 | MP0003123_paternal_imprinting | 1.83689321 |
22 | MP0010352_gastrointestinal_tract_polyps | 1.81145880 |
23 | MP0000490_abnormal_crypts_of | 1.80441937 |
24 | MP0005397_hematopoietic_system_phenotyp | 1.64822746 |
25 | MP0001545_abnormal_hematopoietic_system | 1.64822746 |
26 | MP0009333_abnormal_splenocyte_physiolog | 1.64375327 |
27 | MP0003191_abnormal_cellular_cholesterol | 1.63558725 |
28 | MP0006035_abnormal_mitochondrial_morpho | 1.57340000 |
29 | MP0002019_abnormal_tumor_incidence | 1.52122856 |
30 | MP0002796_impaired_skin_barrier | 1.50234457 |
31 | MP0009697_abnormal_copulation | 1.49701860 |
32 | MP0001672_abnormal_embryogenesis/_devel | 1.49229807 |
33 | MP0005380_embryogenesis_phenotype | 1.49229807 |
34 | MP0000313_abnormal_cell_death | 1.48126191 |
35 | MP0001697_abnormal_embryo_size | 1.47836785 |
36 | MP0003186_abnormal_redox_activity | 1.45434279 |
37 | MP0002080_prenatal_lethality | 1.43674060 |
38 | MP0010030_abnormal_orbit_morphology | 1.43054657 |
39 | MP0004808_abnormal_hematopoietic_stem | 1.37419543 |
40 | MP0003315_abnormal_perineum_morphology | 1.34846253 |
41 | MP0003984_embryonic_growth_retardation | 1.34713135 |
42 | MP0003763_abnormal_thymus_physiology | 1.33694650 |
43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.33489871 |
44 | MP0002088_abnormal_embryonic_growth/wei | 1.31971320 |
45 | MP0002398_abnormal_bone_marrow | 1.31434790 |
46 | MP0005464_abnormal_platelet_physiology | 1.30855902 |
47 | MP0010307_abnormal_tumor_latency | 1.29505609 |
48 | MP0004133_heterotaxia | 1.27196278 |
49 | MP0000689_abnormal_spleen_morphology | 1.24949958 |
50 | MP0002085_abnormal_embryonic_tissue | 1.22392602 |
51 | MP0005075_abnormal_melanosome_morpholog | 1.22130810 |
52 | MP0002722_abnormal_immune_system | 1.21099149 |
53 | MP0002086_abnormal_extraembryonic_tissu | 1.20198251 |
54 | MP0002132_abnormal_respiratory_system | 1.18043585 |
55 | MP0001849_ear_inflammation | 1.16597500 |
56 | MP0000703_abnormal_thymus_morphology | 1.14019733 |
57 | MP0001835_abnormal_antigen_presentation | 1.13620153 |
58 | MP0003283_abnormal_digestive_organ | 1.10050426 |
59 | MP0003656_abnormal_erythrocyte_physiolo | 1.09703502 |
60 | MP0000678_abnormal_parathyroid_gland | 1.09343240 |
61 | MP0002429_abnormal_blood_cell | 1.09206479 |
62 | MP0002210_abnormal_sex_determination | 1.08073430 |
63 | MP0002084_abnormal_developmental_patter | 1.07743407 |
64 | MP0002877_abnormal_melanocyte_morpholog | 1.07438010 |
65 | MP0000858_altered_metastatic_potential | 1.06998141 |
66 | MP0004185_abnormal_adipocyte_glucose | 1.06026803 |
67 | MP0004197_abnormal_fetal_growth/weight/ | 1.04903651 |
68 | MP0006292_abnormal_olfactory_placode | 1.04146898 |
69 | MP0004947_skin_inflammation | 1.04138802 |
70 | MP0000716_abnormal_immune_system | 1.00610636 |
71 | MP0001873_stomach_inflammation | 0.98604857 |
72 | MP0002160_abnormal_reproductive_system | 0.96850551 |
73 | MP0001145_abnormal_male_reproductive | 0.95986700 |
74 | MP0001293_anophthalmia | 0.94479507 |
75 | MP0001727_abnormal_embryo_implantation | 0.93813762 |
76 | MP0001800_abnormal_humoral_immune | 0.91838894 |
77 | MP0002452_abnormal_antigen_presenting | 0.91233387 |
78 | MP0008469_abnormal_protein_level | 0.90907056 |
79 | MP0001881_abnormal_mammary_gland | 0.89786111 |
80 | MP0001845_abnormal_inflammatory_respons | 0.88928829 |
81 | MP0002420_abnormal_adaptive_immunity | 0.88727068 |
82 | MP0001819_abnormal_immune_cell | 0.87694117 |
83 | MP0001119_abnormal_female_reproductive | 0.87562438 |
84 | MP0005387_immune_system_phenotype | 0.87514454 |
85 | MP0001790_abnormal_immune_system | 0.87514454 |
86 | MP0006082_CNS_inflammation | 0.87149936 |
87 | MP0003303_peritoneal_inflammation | 0.86885266 |
88 | MP0005330_cardiomyopathy | 0.84279470 |
89 | MP0001853_heart_inflammation | 0.83709979 |
90 | MP0005389_reproductive_system_phenotype | 0.82928991 |
91 | MP0009379_abnormal_foot_pigmentation | 0.82721765 |
92 | MP0009764_decreased_sensitivity_to | 0.82527576 |
93 | MP0009278_abnormal_bone_marrow | 0.81886831 |
94 | MP0009785_altered_susceptibility_to | 0.81850309 |
95 | MP0005076_abnormal_cell_differentiation | 0.81346314 |
96 | MP0009931_abnormal_skin_appearance | 0.80785816 |
97 | MP0003075_altered_response_to | 0.80264291 |
98 | MP0003221_abnormal_cardiomyocyte_apopto | 0.78970318 |
99 | MP0001929_abnormal_gametogenesis | 0.78905156 |
100 | MP0000358_abnormal_cell_content/ | 0.78843182 |
101 | MP0002405_respiratory_system_inflammati | 0.78813014 |
102 | MP0003121_genomic_imprinting | 0.78757143 |
103 | MP0000653_abnormal_sex_gland | 0.78431558 |
104 | MP0009672_abnormal_birth_weight | 0.78243236 |
105 | MP0005023_abnormal_wound_healing | 0.76894470 |
106 | MP0002723_abnormal_immune_serum | 0.76123899 |
107 | MP0004782_abnormal_surfactant_physiolog | 0.74965550 |
108 | MP0005671_abnormal_response_to | 0.74770092 |
109 | MP0003453_abnormal_keratinocyte_physiol | 0.74762603 |
110 | MP0004147_increased_porphyrin_level | 0.74713964 |
111 | MP0005000_abnormal_immune_tolerance | 0.73543758 |
112 | MP0000598_abnormal_liver_morphology | 0.73506115 |
113 | MP0003890_abnormal_embryonic-extraembry | 0.73214277 |
114 | MP0003941_abnormal_skin_development | 0.73066437 |
115 | MP0005025_abnormal_response_to | 0.72960587 |
116 | MP0005384_cellular_phenotype | 0.72897686 |
117 | MP0003436_decreased_susceptibility_to | 0.71703112 |
118 | MP0000465_gastrointestinal_hemorrhage | 0.71164911 |
119 | MP0005621_abnormal_cell_physiology | 0.71034401 |
120 | MP0003566_abnormal_cell_adhesion | 0.70372019 |
121 | MP0006036_abnormal_mitochondrial_physio | 0.67608208 |
122 | MP0002148_abnormal_hypersensitivity_rea | 0.65641985 |
123 | MP0000685_abnormal_immune_system | 0.63205181 |
124 | MP0000477_abnormal_intestine_morphology | 0.62716620 |
125 | MP0001919_abnormal_reproductive_system | 0.59202512 |
126 | MP0002111_abnormal_tail_morphology | 0.58653553 |
127 | MP0010155_abnormal_intestine_physiology | 0.58561050 |
128 | MP0005501_abnormal_skin_physiology | 0.58442253 |
129 | MP0003448_altered_tumor_morphology | 0.56204271 |
130 | MP0001764_abnormal_homeostasis | 0.55329212 |
131 | MP0000343_altered_response_to | 0.54755221 |
132 | MP0005174_abnormal_tail_pigmentation | 0.54649156 |
133 | MP0002419_abnormal_innate_immunity | 0.54477079 |
134 | MP0008260_abnormal_autophagy | 0.53714021 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.14158579 |
2 | Reticulocytopenia (HP:0001896) | 4.93568491 |
3 | Breast hypoplasia (HP:0003187) | 4.33212239 |
4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.28048711 |
5 | Abnormal number of erythroid precursors (HP:0012131) | 4.04353645 |
6 | Carpal bone hypoplasia (HP:0001498) | 3.84319158 |
7 | Chromsome breakage (HP:0040012) | 3.72194250 |
8 | Colon cancer (HP:0003003) | 3.68105411 |
9 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.63467586 |
10 | Ragged-red muscle fibers (HP:0003200) | 3.61343341 |
11 | Patellar aplasia (HP:0006443) | 3.36443645 |
12 | Progressive muscle weakness (HP:0003323) | 3.22704456 |
13 | Selective tooth agenesis (HP:0001592) | 3.20788590 |
14 | Agnosia (HP:0010524) | 3.19426147 |
15 | Absent thumb (HP:0009777) | 3.19339841 |
16 | Aplasia/Hypoplasia of the patella (HP:0006498) | 3.12732997 |
17 | Oral leukoplakia (HP:0002745) | 3.11380407 |
18 | Rough bone trabeculation (HP:0100670) | 3.07640254 |
19 | Pallor (HP:0000980) | 3.02894262 |
20 | Cerebral hypomyelination (HP:0006808) | 2.95804792 |
21 | Abnormality of the preputium (HP:0100587) | 2.95367025 |
22 | Vacuolated lymphocytes (HP:0001922) | 2.94847333 |
23 | Macrocytic anemia (HP:0001972) | 2.90070553 |
24 | Degeneration of anterior horn cells (HP:0002398) | 2.89804979 |
25 | Abnormality of the anterior horn cell (HP:0006802) | 2.89804979 |
26 | Meckel diverticulum (HP:0002245) | 2.89524702 |
27 | Vertebral compression fractures (HP:0002953) | 2.84487747 |
28 | Aplastic anemia (HP:0001915) | 2.83376382 |
29 | Duplicated collecting system (HP:0000081) | 2.81845241 |
30 | Abnormality of the ileum (HP:0001549) | 2.81761336 |
31 | Increased cerebral lipofuscin (HP:0011813) | 2.80624719 |
32 | Absent radius (HP:0003974) | 2.77327393 |
33 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.76497986 |
34 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.70539480 |
35 | Trismus (HP:0000211) | 2.68946121 |
36 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.68096747 |
37 | Ependymoma (HP:0002888) | 2.66143858 |
38 | Abnormal gallbladder physiology (HP:0012438) | 2.66105050 |
39 | Cholecystitis (HP:0001082) | 2.66105050 |
40 | Abnormality of chromosome stability (HP:0003220) | 2.63789581 |
41 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.61529119 |
42 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.61529119 |
43 | Abnormality of glycolipid metabolism (HP:0010969) | 2.61529119 |
44 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.60873229 |
45 | Increased IgM level (HP:0003496) | 2.60299409 |
46 | Progressive external ophthalmoplegia (HP:0000590) | 2.58024266 |
47 | Increased intramyocellular lipid droplets (HP:0012240) | 2.56429851 |
48 | Medulloblastoma (HP:0002885) | 2.54423015 |
49 | Absent forearm bone (HP:0003953) | 2.53329571 |
50 | Aplasia involving forearm bones (HP:0009822) | 2.53329571 |
51 | Bone marrow hypocellularity (HP:0005528) | 2.52895975 |
52 | Entropion (HP:0000621) | 2.50895578 |
53 | Microretrognathia (HP:0000308) | 2.47999666 |
54 | Hepatosplenomegaly (HP:0001433) | 2.47612485 |
55 | Type I transferrin isoform profile (HP:0003642) | 2.46992596 |
56 | Multiple enchondromatosis (HP:0005701) | 2.46875390 |
57 | Increased muscle lipid content (HP:0009058) | 2.45499535 |
58 | 11 pairs of ribs (HP:0000878) | 2.44473736 |
59 | Myelodysplasia (HP:0002863) | 2.40509181 |
60 | Increased serum ferritin (HP:0003281) | 2.40433102 |
61 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.38026738 |
62 | Abnormality of the renal collecting system (HP:0004742) | 2.37613149 |
63 | Premature graying of hair (HP:0002216) | 2.36709545 |
64 | 3-Methylglutaconic aciduria (HP:0003535) | 2.36432836 |
65 | Duodenal stenosis (HP:0100867) | 2.34568248 |
66 | Small intestinal stenosis (HP:0012848) | 2.34568248 |
67 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.31360148 |
68 | Hepatic necrosis (HP:0002605) | 2.31192159 |
69 | Mediastinal lymphadenopathy (HP:0100721) | 2.28847341 |
70 | Cellular immunodeficiency (HP:0005374) | 2.28194722 |
71 | Abnormal lung lobation (HP:0002101) | 2.27234569 |
72 | Thrombocytosis (HP:0001894) | 2.27024690 |
73 | Neoplasm of the pancreas (HP:0002894) | 2.26938000 |
74 | Triphalangeal thumb (HP:0001199) | 2.25505774 |
75 | Impulsivity (HP:0100710) | 2.24948179 |
76 | Ectopic kidney (HP:0000086) | 2.24756505 |
77 | Amaurosis fugax (HP:0100576) | 2.24740921 |
78 | Abnormal trabecular bone morphology (HP:0100671) | 2.24661060 |
79 | Lymphoma (HP:0002665) | 2.20803328 |
80 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.20225334 |
81 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.16435066 |
82 | Tracheoesophageal fistula (HP:0002575) | 2.16027298 |
83 | Recurrent abscess formation (HP:0002722) | 2.15547099 |
84 | Progressive neurologic deterioration (HP:0002344) | 2.15322240 |
85 | Loss of speech (HP:0002371) | 2.15017216 |
86 | Mitochondrial inheritance (HP:0001427) | 2.14655964 |
87 | Rhabdomyosarcoma (HP:0002859) | 2.14477304 |
88 | Ureteral duplication (HP:0000073) | 2.14393680 |
89 | Microvesicular hepatic steatosis (HP:0001414) | 2.13497459 |
90 | Cerebral palsy (HP:0100021) | 2.12680858 |
91 | Optic nerve coloboma (HP:0000588) | 2.12625223 |
92 | Hypertensive crisis (HP:0100735) | 2.11806330 |
93 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.11351583 |
94 | Dicarboxylic aciduria (HP:0003215) | 2.11351583 |
95 | Pancytopenia (HP:0001876) | 2.11219456 |
96 | Sloping forehead (HP:0000340) | 2.11212777 |
97 | Increased CSF lactate (HP:0002490) | 2.10980858 |
98 | Poikiloderma (HP:0001029) | 2.08657638 |
99 | Abnormal protein glycosylation (HP:0012346) | 2.08208947 |
100 | Abnormal glycosylation (HP:0012345) | 2.08208947 |
101 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.08208947 |
102 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.08208947 |
103 | Agammaglobulinemia (HP:0004432) | 2.08170168 |
104 | Secondary amenorrhea (HP:0000869) | 2.07563308 |
105 | Increased serum lactate (HP:0002151) | 2.07058624 |
106 | Premature ovarian failure (HP:0008209) | 2.05978534 |
107 | Recurrent viral infections (HP:0004429) | 2.05698517 |
108 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.03461378 |
109 | Lactic acidosis (HP:0003128) | 2.02582649 |
110 | IgM deficiency (HP:0002850) | 2.01676880 |
111 | Irregular epiphyses (HP:0010582) | 2.00520312 |
112 | Gastrointestinal dysmotility (HP:0002579) | 1.98565594 |
113 | Supernumerary spleens (HP:0009799) | 1.98471253 |
114 | Exercise intolerance (HP:0003546) | 1.95935913 |
115 | Testicular atrophy (HP:0000029) | 1.95367759 |
116 | Petechiae (HP:0000967) | 1.95089902 |
117 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.94589793 |
118 | Increased IgE level (HP:0003212) | 1.93117145 |
119 | Abnormality of the duodenum (HP:0002246) | 1.92641671 |
120 | Chronic obstructive pulmonary disease (HP:0006510) | 1.92439667 |
121 | Obstructive lung disease (HP:0006536) | 1.92439667 |
122 | Cleft eyelid (HP:0000625) | 1.91951968 |
123 | Granulocytopenia (HP:0001913) | 1.91498177 |
124 | Atresia of the external auditory canal (HP:0000413) | 1.91069187 |
125 | Reduced antithrombin III activity (HP:0001976) | 1.91010727 |
126 | Neoplasm of the colon (HP:0100273) | 1.90218985 |
127 | Abnormality of DNA repair (HP:0003254) | 1.89771011 |
128 | Clubbing of toes (HP:0100760) | 1.89671872 |
129 | Abnormality of macrophages (HP:0004311) | 1.89666237 |
130 | * Horseshoe kidney (HP:0000085) | 1.89468347 |
131 | Abnormality of the umbilical cord (HP:0010881) | 1.88782828 |
132 | Abnormal number of incisors (HP:0011064) | 1.88618994 |
133 | Nonimmune hydrops fetalis (HP:0001790) | 1.88461559 |
134 | Death in infancy (HP:0001522) | 1.87690645 |
135 | Acute encephalopathy (HP:0006846) | 1.87167574 |
136 | Autoimmune thrombocytopenia (HP:0001973) | 1.85906609 |
137 | Combined immunodeficiency (HP:0005387) | 1.85795423 |
138 | Basal cell carcinoma (HP:0002671) | 1.85771216 |
139 | Fasciculations (HP:0002380) | 1.84120970 |
140 | Rectovaginal fistula (HP:0000143) | 1.84073832 |
141 | Rectal fistula (HP:0100590) | 1.84073832 |
142 | Asplenia (HP:0001746) | 1.83909688 |
143 | Stenosis of the external auditory canal (HP:0000402) | 1.83300071 |
144 | Panhypogammaglobulinemia (HP:0003139) | 1.83183067 |
145 | Cellulitis (HP:0100658) | 1.82444416 |
146 | Muscle fiber atrophy (HP:0100295) | 1.82393913 |
147 | Sparse eyelashes (HP:0000653) | 1.82011821 |
148 | Biconcave vertebral bodies (HP:0004586) | 1.81538416 |
149 | Hypergonadotropic hypogonadism (HP:0000815) | 1.80494299 |
150 | Acute necrotizing encephalopathy (HP:0006965) | 1.80460671 |
151 | Abnormality of reticulocytes (HP:0004312) | 1.78954555 |
152 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.78837352 |
153 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.78837352 |
154 | Abnormality of iron homeostasis (HP:0011031) | 1.78395266 |
155 | Slender long bone (HP:0003100) | 1.78149634 |
156 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.76932607 |
157 | Short thumb (HP:0009778) | 1.76359839 |
158 | Type 2 muscle fiber atrophy (HP:0003554) | 1.75785969 |
159 | Hypoplasia of the radius (HP:0002984) | 1.74687893 |
160 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.74508293 |
161 | Orthostatic hypotension (HP:0001278) | 1.74054500 |
162 | Autoimmune hemolytic anemia (HP:0001890) | 1.74030178 |
163 | Poor head control (HP:0002421) | 1.73653775 |
164 | Hepatocellular necrosis (HP:0001404) | 1.72585681 |
165 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.71223147 |
166 | Single umbilical artery (HP:0001195) | 1.71159267 |
167 | Respiratory difficulties (HP:0002880) | 1.70450243 |
168 | Reticulocytosis (HP:0001923) | 1.70128578 |
169 | Opisthotonus (HP:0002179) | 1.68700470 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.07456277 |
2 | VRK2 | 4.28768912 |
3 | WEE1 | 3.72750680 |
4 | CDC7 | 3.02956770 |
5 | EIF2AK1 | 2.98618810 |
6 | SMG1 | 2.61307248 |
7 | PLK4 | 2.51870553 |
8 | EIF2AK3 | 2.51847772 |
9 | SRPK1 | 2.45337772 |
10 | BRSK2 | 2.42166746 |
11 | TTK | 2.28538940 |
12 | NME2 | 2.25274595 |
13 | BCKDK | 2.20355277 |
14 | NEK2 | 2.17407275 |
15 | ERN1 | 2.10918036 |
16 | TSSK6 | 2.04696899 |
17 | PLK1 | 1.93496428 |
18 | TESK2 | 1.88736743 |
19 | STK16 | 1.85767465 |
20 | RPS6KB2 | 1.82009460 |
21 | PASK | 1.78430454 |
22 | VRK1 | 1.75341885 |
23 | EPHA2 | 1.70472549 |
24 | NEK1 | 1.66582226 |
25 | MKNK1 | 1.65804270 |
26 | AURKB | 1.62484237 |
27 | CDK7 | 1.59203120 |
28 | ATR | 1.51965065 |
29 | BRD4 | 1.47118788 |
30 | TAOK2 | 1.45663281 |
31 | BRSK1 | 1.43643150 |
32 | ACVR1B | 1.43049027 |
33 | DAPK1 | 1.41798944 |
34 | PLK3 | 1.40099307 |
35 | ZAK | 1.39539168 |
36 | SCYL2 | 1.32811481 |
37 | AURKA | 1.31448733 |
38 | IRAK3 | 1.31265718 |
39 | STK4 | 1.30940997 |
40 | DYRK3 | 1.30777993 |
41 | PIM2 | 1.29148574 |
42 | TLK1 | 1.28273233 |
43 | PIM1 | 1.27047930 |
44 | TRIB3 | 1.23277390 |
45 | STK10 | 1.22701553 |
46 | ARAF | 1.21956460 |
47 | CDK4 | 1.21468355 |
48 | CHEK2 | 1.20259768 |
49 | RPS6KA4 | 1.18079600 |
50 | MAP4K1 | 1.16614999 |
51 | BLK | 1.16441839 |
52 | PBK | 1.15153861 |
53 | MAP3K8 | 1.14488043 |
54 | TBK1 | 1.07771619 |
55 | MAP3K10 | 1.04805989 |
56 | MKNK2 | 1.04286904 |
57 | IRAK4 | 1.03053528 |
58 | CHEK1 | 0.97964563 |
59 | KDR | 0.96747197 |
60 | MAP2K3 | 0.90707337 |
61 | EIF2AK2 | 0.89763386 |
62 | MST4 | 0.87816934 |
63 | TESK1 | 0.87255705 |
64 | TGFBR1 | 0.85440148 |
65 | MAP2K2 | 0.83090707 |
66 | ABL2 | 0.81820071 |
67 | PRPF4B | 0.81635120 |
68 | ZAP70 | 0.81075795 |
69 | STK38L | 0.80168669 |
70 | TAF1 | 0.79224822 |
71 | PAK4 | 0.79106974 |
72 | CCNB1 | 0.76425666 |
73 | CSNK2A1 | 0.75924928 |
74 | FLT3 | 0.71923804 |
75 | BTK | 0.71346884 |
76 | CSNK2A2 | 0.71324572 |
77 | JAK3 | 0.69101245 |
78 | CDK12 | 0.68470397 |
79 | DYRK2 | 0.67733799 |
80 | CDK2 | 0.67619210 |
81 | EEF2K | 0.66721993 |
82 | PAK1 | 0.66648522 |
83 | PRKCI | 0.65979343 |
84 | TEC | 0.65193744 |
85 | ATM | 0.64621933 |
86 | IKBKB | 0.63200084 |
87 | LMTK2 | 0.62823941 |
88 | BRAF | 0.60408547 |
89 | DAPK3 | 0.59908071 |
90 | LRRK2 | 0.59209073 |
91 | MATK | 0.55795751 |
92 | CDK8 | 0.55725005 |
93 | RPS6KA5 | 0.53828466 |
94 | YES1 | 0.53751279 |
95 | MAP3K11 | 0.53659137 |
96 | PRKG2 | 0.52982413 |
97 | BMX | 0.51142802 |
98 | CLK1 | 0.50526096 |
99 | MAPK11 | 0.50331219 |
100 | CSNK1G3 | 0.49919883 |
101 | MAP3K6 | 0.48153772 |
102 | TAOK3 | 0.47569039 |
103 | MAP3K3 | 0.47369090 |
104 | MAPKAPK2 | 0.45083175 |
105 | CDK1 | 0.45058904 |
106 | RAF1 | 0.43943281 |
107 | CHUK | 0.41918099 |
108 | NME1 | 0.41828961 |
109 | KIT | 0.41163244 |
110 | MAPKAPK3 | 0.41037828 |
111 | TXK | 0.40665386 |
112 | CDK9 | 0.40522198 |
113 | LIMK1 | 0.40461384 |
114 | STK24 | 0.39789843 |
115 | PDK2 | 0.38843115 |
116 | MAP3K5 | 0.38813823 |
117 | ALK | 0.37934545 |
118 | MAP3K14 | 0.37148476 |
119 | NLK | 0.36748575 |
120 | LYN | 0.35392991 |
121 | RPS6KL1 | 0.35056811 |
122 | RPS6KC1 | 0.35056811 |
123 | CSF1R | 0.35049090 |
124 | TYK2 | 0.35016514 |
125 | ICK | 0.34816944 |
126 | SYK | 0.34224851 |
127 | ILK | 0.31491359 |
128 | MELK | 0.30734285 |
129 | NEK9 | 0.29931153 |
130 | RPS6KA6 | 0.28548815 |
131 | GRK6 | 0.28400610 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.81142631 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.31522603 |
3 | Ribosome_Homo sapiens_hsa03010 | 3.95399494 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.76632212 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.42830584 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 3.29165392 |
7 | Base excision repair_Homo sapiens_hsa03410 | 3.20097480 |
8 | Spliceosome_Homo sapiens_hsa03040 | 3.18194048 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 3.00427108 |
10 | * RNA transport_Homo sapiens_hsa03013 | 2.80227323 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.70195801 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.55187998 |
13 | Cell cycle_Homo sapiens_hsa04110 | 2.40216167 |
14 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.35484812 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.31565120 |
16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.19524280 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.18556889 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.88820716 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.82844503 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.48155284 |
21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.42904533 |
22 | Purine metabolism_Homo sapiens_hsa00230 | 1.38919369 |
23 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.34305625 |
24 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.17248446 |
25 | Protein export_Homo sapiens_hsa03060 | 1.13904588 |
26 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.12957847 |
27 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.11341042 |
28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.10610540 |
29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.94615586 |
30 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.93559485 |
31 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.89659961 |
32 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.88915373 |
33 | Lysosome_Homo sapiens_hsa04142 | 0.87713898 |
34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.84348742 |
35 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.83735511 |
36 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.80320255 |
37 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.78516160 |
38 | Legionellosis_Homo sapiens_hsa05134 | 0.75611769 |
39 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.74013166 |
40 | Parkinsons disease_Homo sapiens_hsa05012 | 0.73409492 |
41 | Huntingtons disease_Homo sapiens_hsa05016 | 0.71466747 |
42 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.70485315 |
43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.70436880 |
44 | Sulfur relay system_Homo sapiens_hsa04122 | 0.70098724 |
45 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.69878216 |
46 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.68679857 |
47 | Viral myocarditis_Homo sapiens_hsa05416 | 0.67946910 |
48 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.65300957 |
49 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.65091688 |
50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.64419372 |
51 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.63546072 |
52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.63445383 |
53 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.62410500 |
54 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.58022444 |
55 | Thyroid cancer_Homo sapiens_hsa05216 | 0.56454335 |
56 | HTLV-I infection_Homo sapiens_hsa05166 | 0.56425473 |
57 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.56324270 |
58 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.55674041 |
59 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.54178823 |
60 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.54153811 |
61 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.53982511 |
62 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.52572510 |
63 | Apoptosis_Homo sapiens_hsa04210 | 0.51916627 |
64 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.50121083 |
65 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.47813598 |
66 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.47441736 |
67 | Salmonella infection_Homo sapiens_hsa05132 | 0.47204730 |
68 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.46832908 |
69 | Shigellosis_Homo sapiens_hsa05131 | 0.46732885 |
70 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.46383796 |
71 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.45426980 |
72 | Galactose metabolism_Homo sapiens_hsa00052 | 0.44430102 |
73 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.44227370 |
74 | Measles_Homo sapiens_hsa05162 | 0.43783580 |
75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43642160 |
76 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.41289172 |
77 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.41122995 |
78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.41001178 |
79 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.40933143 |
80 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.40769980 |
81 | Carbon metabolism_Homo sapiens_hsa01200 | 0.39534473 |
82 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39120923 |
83 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.39005749 |
84 | Other glycan degradation_Homo sapiens_hsa00511 | 0.38329447 |
85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.37920233 |
86 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.36814617 |
87 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36262479 |
88 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.36029306 |
89 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.35124845 |
90 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.35089490 |
91 | Leishmaniasis_Homo sapiens_hsa05140 | 0.34230043 |
92 | Tuberculosis_Homo sapiens_hsa05152 | 0.33969389 |
93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.31997658 |
94 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.31795119 |
95 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.31368897 |
96 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.31244848 |
97 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.30697039 |
98 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.29466847 |
99 | Asthma_Homo sapiens_hsa05310 | 0.29016451 |
100 | Peroxisome_Homo sapiens_hsa04146 | 0.28255337 |
101 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.27986976 |
102 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.26879109 |
103 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.26125092 |
104 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.24653336 |
105 | Influenza A_Homo sapiens_hsa05164 | 0.24089269 |
106 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.23878125 |
107 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.21318786 |
108 | Hepatitis B_Homo sapiens_hsa05161 | 0.21236581 |
109 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.19727034 |
110 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.19298310 |
111 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.16949021 |
112 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.16495791 |
113 | Alcoholism_Homo sapiens_hsa05034 | 0.16368207 |
114 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.15623988 |
115 | Bladder cancer_Homo sapiens_hsa05219 | 0.15034651 |
116 | Alzheimers disease_Homo sapiens_hsa05010 | 0.14151591 |
117 | Allograft rejection_Homo sapiens_hsa05330 | 0.13306730 |
118 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.12393719 |
119 | Pathways in cancer_Homo sapiens_hsa05200 | 0.10390681 |