THSD7A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.27682086
2glomerular visceral epithelial cell development (GO:0072015)5.12100065
3nucleobase catabolic process (GO:0046113)4.97062955
4glomerular epithelial cell development (GO:0072310)4.69963188
5central nervous system neuron axonogenesis (GO:0021955)4.29719858
6behavioral response to nicotine (GO:0035095)4.21548657
7glomerular basement membrane development (GO:0032836)4.21410632
8regulation of short-term neuronal synaptic plasticity (GO:0048172)4.10426872
9neuron cell-cell adhesion (GO:0007158)4.03667752
10establishment of mitochondrion localization (GO:0051654)3.93947379
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.87987775
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.81878674
13negative regulation of dendrite development (GO:2000171)3.78422441
14protein localization to synapse (GO:0035418)3.74430124
15vocalization behavior (GO:0071625)3.73702306
16neuron recognition (GO:0008038)3.70294827
17regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.63269107
18regulation of collateral sprouting (GO:0048670)3.57260654
19ionotropic glutamate receptor signaling pathway (GO:0035235)3.56901120
20synaptic vesicle exocytosis (GO:0016079)3.55029253
21positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.53709871
22axonal fasciculation (GO:0007413)3.48823534
23dendritic spine morphogenesis (GO:0060997)3.43828937
24synaptic transmission, glutamatergic (GO:0035249)3.42245032
25neuron-neuron synaptic transmission (GO:0007270)3.40843966
26establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.40424287
27mitochondrion transport along microtubule (GO:0047497)3.40424287
28axon extension (GO:0048675)3.40352090
29glutamate receptor signaling pathway (GO:0007215)3.39377995
30neural tube formation (GO:0001841)3.36899290
31regulation of glutamate receptor signaling pathway (GO:1900449)3.33989346
32regulation of synaptic vesicle exocytosis (GO:2000300)3.33886028
33locomotory exploration behavior (GO:0035641)3.30944746
34neuronal ion channel clustering (GO:0045161)3.30610919
35neuronal action potential propagation (GO:0019227)3.30477532
36presynaptic membrane assembly (GO:0097105)3.29606863
37regulation of axon guidance (GO:1902667)3.25119471
38negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.20296515
39spinal cord development (GO:0021510)3.19547023
40negative regulation of axon guidance (GO:1902668)3.15874173
41negative regulation of cytosolic calcium ion concentration (GO:0051481)3.14719435
42mechanosensory behavior (GO:0007638)3.14541063
43presynaptic membrane organization (GO:0097090)3.14284537
44synaptic vesicle maturation (GO:0016188)3.14145449
45cell migration in hindbrain (GO:0021535)3.10081610
46transmission of nerve impulse (GO:0019226)3.08316293
47central nervous system myelination (GO:0022010)3.07666894
48axon ensheathment in central nervous system (GO:0032291)3.07666894
49G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06361175
50protein localization to cilium (GO:0061512)3.06269762
51hindbrain development (GO:0030902)3.04906598
52negative regulation of translation, ncRNA-mediated (GO:0040033)3.03105669
53regulation of translation, ncRNA-mediated (GO:0045974)3.03105669
54negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.03105669
55response to auditory stimulus (GO:0010996)3.00711736
56gamma-aminobutyric acid transport (GO:0015812)3.00042941
57neuromuscular synaptic transmission (GO:0007274)2.99753417
58mating behavior (GO:0007617)2.99174709
59behavioral response to ethanol (GO:0048149)2.99157096
60dendrite morphogenesis (GO:0048813)2.98815632
61gamma-aminobutyric acid signaling pathway (GO:0007214)2.98614562
62synaptic vesicle endocytosis (GO:0048488)2.97280866
63cerebellar granule cell differentiation (GO:0021707)2.96946371
64sympathetic nervous system development (GO:0048485)2.95774758
65neurotransmitter-gated ion channel clustering (GO:0072578)2.95719791
66regulation of synapse structural plasticity (GO:0051823)2.94752090
67cerebellar Purkinje cell differentiation (GO:0021702)2.93391627
68glutamate secretion (GO:0014047)2.92174978
69glomerulus development (GO:0032835)2.91853988
70neuron migration (GO:0001764)2.91534828
71regulation of synaptic transmission, glutamatergic (GO:0051966)2.91385833
72regulation of synaptic vesicle transport (GO:1902803)2.90135124
73regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.89694911
74layer formation in cerebral cortex (GO:0021819)2.89387107
75axonogenesis (GO:0007409)2.86468938
76postsynaptic membrane organization (GO:0001941)2.85852391
77regulation of neuronal synaptic plasticity (GO:0048168)2.84982611
78regulation of axon extension involved in axon guidance (GO:0048841)2.84486839
79positive regulation of synapse maturation (GO:0090129)2.83038948
80cerebral cortex radially oriented cell migration (GO:0021799)2.82555168
81neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.81771594
82prepulse inhibition (GO:0060134)2.80282989
83membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80192141
84neuron projection extension (GO:1990138)2.78564731
85kidney morphogenesis (GO:0060993)2.78338537
86forebrain neuron differentiation (GO:0021879)2.78116590
87innervation (GO:0060384)2.77074291
88regulation of long-term neuronal synaptic plasticity (GO:0048169)2.76415190
89neurotransmitter secretion (GO:0007269)2.76118597
90regulation of excitatory postsynaptic membrane potential (GO:0060079)2.76075110
91membrane hyperpolarization (GO:0060081)2.75820247
92startle response (GO:0001964)2.74495717
93retina layer formation (GO:0010842)2.74255837
94central nervous system projection neuron axonogenesis (GO:0021952)2.73296478
95exploration behavior (GO:0035640)2.72580584
96synapse assembly (GO:0007416)2.72294902
97adult walking behavior (GO:0007628)2.72161139
98nonmotile primary cilium assembly (GO:0035058)2.70969070
99positive regulation of dendritic spine morphogenesis (GO:0061003)2.70490275
100cardiac ventricle formation (GO:0003211)2.69981854
101membrane depolarization during action potential (GO:0086010)2.69929674
102regulation of postsynaptic membrane potential (GO:0060078)2.69813640
103synaptic vesicle docking involved in exocytosis (GO:0016081)2.69346178
104positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.69326783
105heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.69260584
106peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.68898026
107dendrite development (GO:0016358)2.68692905
108epithelial cell differentiation involved in kidney development (GO:0035850)2.67593433
109limb bud formation (GO:0060174)2.67086292
110urinary tract smooth muscle contraction (GO:0014848)2.66836814
111regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.66323553
112olfactory bulb development (GO:0021772)2.65643449
113apical protein localization (GO:0045176)2.64329722
114regulation of dendritic spine morphogenesis (GO:0061001)2.63401962
115long-term memory (GO:0007616)2.63207434
116auditory behavior (GO:0031223)2.62975152
117synaptic transmission, cholinergic (GO:0007271)2.62883300
118positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.62597144
119striatum development (GO:0021756)2.62164163
120negative regulation of axonogenesis (GO:0050771)2.61797777
121positive regulation of synapse assembly (GO:0051965)2.61770370
122long-term synaptic potentiation (GO:0060291)2.61454186
123regulation of respiratory system process (GO:0044065)2.61275890
124negative regulation of axon extension (GO:0030517)2.60941892
125regulation of synapse maturation (GO:0090128)2.60904929
126positive regulation of membrane potential (GO:0045838)2.60194347
127response to pheromone (GO:0019236)2.58738223
128substrate-independent telencephalic tangential migration (GO:0021826)2.58738079
129substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.58738079
130negative regulation of neurotransmitter transport (GO:0051589)2.58510253
131retinal ganglion cell axon guidance (GO:0031290)2.55435615
132neuronal action potential (GO:0019228)2.54751855
133behavioral defense response (GO:0002209)2.53854781
134behavioral fear response (GO:0001662)2.53854781
135cardiac chamber formation (GO:0003207)2.53785051
136regulation of neurotransmitter secretion (GO:0046928)2.53114654
137cochlea development (GO:0090102)2.52729409
138cell differentiation in hindbrain (GO:0021533)2.52420390
139cellular potassium ion homeostasis (GO:0030007)2.51985551
140regulation of axon extension (GO:0030516)2.51214504
141synapse organization (GO:0050808)2.50680969
142membrane depolarization (GO:0051899)2.50201673
143synaptic transmission, dopaminergic (GO:0001963)2.49920607
144positive regulation of action potential (GO:0045760)2.49750595
145regulation of neurotransmitter transport (GO:0051588)2.49389943
146regulation of extent of cell growth (GO:0061387)2.48942579
147adult behavior (GO:0030534)2.48890076
148positive regulation of synaptic transmission, GABAergic (GO:0032230)2.48728600
149neuron projection extension involved in neuron projection guidance (GO:1902284)2.48467140
150axon extension involved in axon guidance (GO:0048846)2.48467140
151ganglion development (GO:0061548)2.48231428

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.66847214
2GBX2_23144817_ChIP-Seq_PC3_Human3.85836072
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.91284675
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.86107140
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.85553556
6RBPJ_22232070_ChIP-Seq_NCS_Mouse2.66715112
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.59558557
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.59558557
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.57533398
10EED_16625203_ChIP-ChIP_MESCs_Mouse2.53872813
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.50186909
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.48971513
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.45760915
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41484655
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.35186877
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.28816482
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.14850557
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.13454476
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.11992102
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.07503423
21AR_21572438_ChIP-Seq_LNCaP_Human2.02176501
22TAF15_26573619_Chip-Seq_HEK293_Human1.96404255
23BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.93286615
24DROSHA_22980978_ChIP-Seq_HELA_Human1.92219858
25ZFP57_27257070_Chip-Seq_ESCs_Mouse1.88731615
26PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.87354332
27* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.83607079
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.80287616
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79528081
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.78160411
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.76605034
32REST_21632747_ChIP-Seq_MESCs_Mouse1.76207735
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.75942354
34RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.74496747
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.70163739
36* SMAD4_21799915_ChIP-Seq_A2780_Human1.68432743
37* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.66611096
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.62926865
39EWS_26573619_Chip-Seq_HEK293_Human1.62272785
40* P300_19829295_ChIP-Seq_ESCs_Human1.62076137
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.61266063
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60755037
43* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.60016819
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.58039379
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.55262947
46* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52176883
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49487144
48RARB_27405468_Chip-Seq_BRAIN_Mouse1.48343323
49* SMAD3_21741376_ChIP-Seq_EPCs_Human1.47885024
50* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42980586
51* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.38358905
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.38024154
53* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37853006
54AHR_22903824_ChIP-Seq_MCF-7_Human1.36712563
55* STAT3_23295773_ChIP-Seq_U87_Human1.36081667
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.36078601
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.35497482
58TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33460943
59BCAT_22108803_ChIP-Seq_LS180_Human1.31932731
60NR3C1_23031785_ChIP-Seq_PC12_Mouse1.31792264
61ARNT_22903824_ChIP-Seq_MCF-7_Human1.31739998
62FUS_26573619_Chip-Seq_HEK293_Human1.31315082
63REST_18959480_ChIP-ChIP_MESCs_Mouse1.31234502
64WT1_25993318_ChIP-Seq_PODOCYTE_Human1.30683748
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30485596
66CBP_20019798_ChIP-Seq_JUKART_Human1.30485596
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.29805675
68SOX2_21211035_ChIP-Seq_LN229_Gbm1.28763372
69SMAD_19615063_ChIP-ChIP_OVARY_Human1.28067097
70ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.27342824
71* RNF2_27304074_Chip-Seq_NSC_Mouse1.26529180
72ER_23166858_ChIP-Seq_MCF-7_Human1.24797061
73RING1B_27294783_Chip-Seq_NPCs_Mouse1.24367257
74IGF1R_20145208_ChIP-Seq_DFB_Human1.24026717
75RING1B_27294783_Chip-Seq_ESCs_Mouse1.22458360
76AR_25329375_ChIP-Seq_VCAP_Human1.21837710
77KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.21691397
78CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.21513046
79* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.20619965
80LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18161910
81TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17422924
82IKZF1_21737484_ChIP-ChIP_HCT116_Human1.16984501
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.16663308
84YAP1_20516196_ChIP-Seq_MESCs_Mouse1.16575783
85* TCF4_23295773_ChIP-Seq_U87_Human1.15784645
86SOX9_26525672_Chip-Seq_HEART_Mouse1.15103135
87STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15008047
88* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14876140
89WT1_19549856_ChIP-ChIP_CCG9911_Human1.13752989
90NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.12983361
91NANOG_18555785_Chip-Seq_ESCs_Mouse1.11902562
92EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.11625813
93UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.10239287
94EP300_21415370_ChIP-Seq_HL-1_Mouse1.09913180
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09630634
96AR_19668381_ChIP-Seq_PC3_Human1.09363793
97NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09356901
98RUNX2_22187159_ChIP-Seq_PCA_Human1.09352822
99ERG_21242973_ChIP-ChIP_JURKAT_Human1.08076873
100KDM2B_26808549_Chip-Seq_REH_Human1.05658412
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05219233
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05219233
103TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04026215
104ZNF274_21170338_ChIP-Seq_K562_Hela1.03734065
105TP53_18474530_ChIP-ChIP_U2OS_Human1.02887915
106EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02737883
107P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00816937
108PRDM14_20953172_ChIP-Seq_ESCs_Human1.00108689
109MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99705576
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98839675
111TP53_16413492_ChIP-PET_HCT116_Human0.98405048
112SMAD4_21741376_ChIP-Seq_HESCs_Human0.98209713
113CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98183078
114SMAD3_21741376_ChIP-Seq_HESCs_Human0.97927099
115VDR_22108803_ChIP-Seq_LS180_Human0.97604332
116TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97389732
117EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96707693
118JUN_21703547_ChIP-Seq_K562_Human0.95589397
119* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95353498

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.22213889
2MP0003880_abnormal_central_pattern4.20450874
3MP0003635_abnormal_synaptic_transmissio3.10539405
4MP0004270_analgesia3.00320344
5MP0002822_catalepsy2.58474400
6MP0002063_abnormal_learning/memory/cond2.55747747
7MP0009046_muscle_twitch2.55527671
8MP0009745_abnormal_behavioral_response2.54733507
9MP0001486_abnormal_startle_reflex2.51928278
10MP0002064_seizures2.41329417
11MP0002272_abnormal_nervous_system2.33308780
12MP0002572_abnormal_emotion/affect_behav2.31295618
13MP0000778_abnormal_nervous_system2.22908462
14MP0005423_abnormal_somatic_nervous2.20512151
15MP0001968_abnormal_touch/_nociception2.19849758
16MP0002734_abnormal_mechanical_nocicepti2.16302582
17MP0002735_abnormal_chemical_nociception2.08955045
18MP0003890_abnormal_embryonic-extraembry1.90377761
19MP0002184_abnormal_innervation1.87206658
20MP0006276_abnormal_autonomic_nervous1.86570220
21MP0005551_abnormal_eye_electrophysiolog1.84019940
22MP0005499_abnormal_olfactory_system1.83499951
23MP0002067_abnormal_sensory_capabilities1.80258483
24MP0001299_abnormal_eye_distance/1.67806171
25MP0003121_genomic_imprinting1.67174627
26MP0001440_abnormal_grooming_behavior1.66713079
27MP0008789_abnormal_olfactory_epithelium1.66683812
28MP0005623_abnormal_meninges_morphology1.65582324
29MP0001984_abnormal_olfaction1.64354450
30MP0004885_abnormal_endolymph1.63671789
31MP0001529_abnormal_vocalization1.62188966
32MP0001188_hyperpigmentation1.59423341
33MP0002638_abnormal_pupillary_reflex1.59359233
34MP0002736_abnormal_nociception_after1.56340490
35MP0000955_abnormal_spinal_cord1.55703396
36MP0002882_abnormal_neuron_morphology1.54631289
37MP0002557_abnormal_social/conspecific_i1.53058099
38MP0001970_abnormal_pain_threshold1.52038330
39MP0004742_abnormal_vestibular_system1.50024847
40MP0004924_abnormal_behavior1.49580249
41MP0005386_behavior/neurological_phenoty1.49580249
42MP0000920_abnormal_myelination1.48009673
43MP0002733_abnormal_thermal_nociception1.46868297
44MP0006072_abnormal_retinal_apoptosis1.43158503
45MP0001501_abnormal_sleep_pattern1.41569823
46MP0003787_abnormal_imprinting1.41267210
47MP0004133_heterotaxia1.40018011
48MP0001502_abnormal_circadian_rhythm1.38464419
49MP0004811_abnormal_neuron_physiology1.37895628
50MP0006292_abnormal_olfactory_placode1.36538808
51MP0005409_darkened_coat_color1.36033682
52MP0008569_lethality_at_weaning1.32593915
53MP0010386_abnormal_urinary_bladder1.30730719
54MP0000516_abnormal_urinary_system1.28196528
55MP0005367_renal/urinary_system_phenotyp1.28196528
56MP0005646_abnormal_pituitary_gland1.25873975
57MP0001905_abnormal_dopamine_level1.25844710
58MP0002752_abnormal_somatic_nervous1.23086762
59MP0002066_abnormal_motor_capabilities/c1.22791989
60MP0004272_abnormal_basement_membrane1.20933552
61MP0005171_absent_coat_pigmentation1.19691741
62MP0002751_abnormal_autonomic_nervous1.18294393
63MP0000534_abnormal_ureter_morphology1.16801052
64MP0003119_abnormal_digestive_system1.15295594
65MP0005503_abnormal_tendon_morphology1.13768188
66MP0003122_maternal_imprinting1.13716505
67MP0003634_abnormal_glial_cell1.12011828
68MP0002152_abnormal_brain_morphology1.11593197
69MP0002928_abnormal_bile_duct1.10254368
70MP0000537_abnormal_urethra_morphology1.10209789
71MP0002090_abnormal_vision1.09848295
72MP0003329_amyloid_beta_deposits1.09691564
73MP0009780_abnormal_chondrocyte_physiolo1.08477538
74MP0005187_abnormal_penis_morphology1.07688502
75MP0002229_neurodegeneration1.07350144
76MP0002234_abnormal_pharynx_morphology1.06341765
77MP0004142_abnormal_muscle_tone1.05303514
78MP0005645_abnormal_hypothalamus_physiol1.02943363
79MP0003942_abnormal_urinary_system1.02044984
80MP0001963_abnormal_hearing_physiology1.01783020
81MP0004858_abnormal_nervous_system1.01699774
82MP0001879_abnormal_lymphatic_vessel1.00411270
83MP0003315_abnormal_perineum_morphology1.00073889
84MP0000647_abnormal_sebaceous_gland0.99551522
85MP0001177_atelectasis0.98326561
86MP0002102_abnormal_ear_morphology0.95655656
87MP0000631_abnormal_neuroendocrine_gland0.95606422
88MP0000751_myopathy0.93817330
89MP0005195_abnormal_posterior_eye0.92369878
90MP0003632_abnormal_nervous_system0.91798192
91MP0005253_abnormal_eye_physiology0.91664584
92MP0002233_abnormal_nose_morphology0.91484756
93MP0000569_abnormal_digit_pigmentation0.89774318
94MP0004085_abnormal_heartbeat0.89071060
95MP0003631_nervous_system_phenotype0.88885735
96MP0001286_abnormal_eye_development0.88489555
97MP0003938_abnormal_ear_development0.88283137
98MP0003861_abnormal_nervous_system0.88212312
99MP0000026_abnormal_inner_ear0.86827000
100MP0001346_abnormal_lacrimal_gland0.85886568
101MP0003385_abnormal_body_wall0.85851488
102MP0010368_abnormal_lymphatic_system0.85555348
103MP0004036_abnormal_muscle_relaxation0.84729074
104MP0001485_abnormal_pinna_reflex0.84648361
105MP0002081_perinatal_lethality0.84396563
106MP0002909_abnormal_adrenal_gland0.84183905
107MP0002938_white_spotting0.84081357
108MP0000566_synostosis0.83632582
109MP0003633_abnormal_nervous_system0.82304611
110MP0000462_abnormal_digestive_system0.81857483
111MP0003137_abnormal_impulse_conducting0.81857438
112MP0009250_abnormal_appendicular_skeleto0.81275194
113MP0008877_abnormal_DNA_methylation0.80722143
114MP0002069_abnormal_eating/drinking_beha0.80382693
115MP0004043_abnormal_pH_regulation0.79020382
116MP0001661_extended_life_span0.78588467
117MP0003935_abnormal_craniofacial_develop0.78552489
118MP0004233_abnormal_muscle_weight0.78272358
119MP0010030_abnormal_orbit_morphology0.77319624
120MP0004145_abnormal_muscle_electrophysio0.76661336
121MP0003755_abnormal_palate_morphology0.76604435
122MP0000538_abnormal_urinary_bladder0.75433750
123MP0001293_anophthalmia0.74726256
124MP0002108_abnormal_muscle_morphology0.73200888
125MP0000427_abnormal_hair_cycle0.73025134
126MP0003937_abnormal_limbs/digits/tail_de0.72842904
127MP0005394_taste/olfaction_phenotype0.71729298
128MP0000049_abnormal_middle_ear0.70053091

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.92995460
2Myokymia (HP:0002411)4.23683309
3Epileptic encephalopathy (HP:0200134)3.77716988
4Febrile seizures (HP:0002373)3.73670881
5Focal seizures (HP:0007359)3.71709329
6Progressive cerebellar ataxia (HP:0002073)3.45832600
7Atonic seizures (HP:0010819)3.29158117
8Action tremor (HP:0002345)3.20754001
9Hepatoblastoma (HP:0002884)3.06565385
10Cutaneous finger syndactyly (HP:0010554)3.00698006
11Congenital stationary night blindness (HP:0007642)2.98808422
12Midline defect of the nose (HP:0004122)2.86171462
13Renal hypoplasia (HP:0000089)2.86097638
14Focal segmental glomerulosclerosis (HP:0000097)2.85865306
15Hyperventilation (HP:0002883)2.82910336
16Broad-based gait (HP:0002136)2.82669323
17Pachygyria (HP:0001302)2.80477859
18Chronic hepatic failure (HP:0100626)2.76582789
19Lissencephaly (HP:0001339)2.71324318
20Supranuclear gaze palsy (HP:0000605)2.71277178
21Absence seizures (HP:0002121)2.66465869
22Protruding tongue (HP:0010808)2.63637188
23Excessive salivation (HP:0003781)2.61835568
24Drooling (HP:0002307)2.61835568
25Aqueductal stenosis (HP:0002410)2.61199467
26Nephronophthisis (HP:0000090)2.52589862
27Abnormality of the corticospinal tract (HP:0002492)2.51095230
28Morphological abnormality of the middle ear (HP:0008609)2.49472735
29Degeneration of the lateral corticospinal tracts (HP:0002314)2.47687855
30Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.47687855
31Dialeptic seizures (HP:0011146)2.46647020
32Molar tooth sign on MRI (HP:0002419)2.46324331
33Abnormality of midbrain morphology (HP:0002418)2.46324331
34Aplasia involving bones of the extremities (HP:0009825)2.45862144
35Aplasia involving bones of the upper limbs (HP:0009823)2.45862144
36Aplasia of the phalanges of the hand (HP:0009802)2.45862144
37Cutaneous syndactyly (HP:0012725)2.45854828
38Termporal pattern (HP:0011008)2.45378353
39Insidious onset (HP:0003587)2.45378353
40Absent speech (HP:0001344)2.44526992
41Vitreoretinal degeneration (HP:0000655)2.42598013
42Medial flaring of the eyebrow (HP:0010747)2.40825512
43Generalized tonic-clonic seizures (HP:0002069)2.38128102
44True hermaphroditism (HP:0010459)2.36699056
45Blue irides (HP:0000635)2.35460534
46Pancreatic fibrosis (HP:0100732)2.34113640
47Central scotoma (HP:0000603)2.31078004
48Gaze-evoked nystagmus (HP:0000640)2.28881197
49Abnormality of the renal medulla (HP:0100957)2.27858081
50Coronal craniosynostosis (HP:0004440)2.26966714
51Short 4th metacarpal (HP:0010044)2.26455171
52Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.26455171
53Ankle clonus (HP:0011448)2.26347911
54Exotropia (HP:0000577)2.26111416
55Scanning speech (HP:0002168)2.24214628
56Pancreatic cysts (HP:0001737)2.23030980
57Congenital primary aphakia (HP:0007707)2.22385590
58Abnormality of macular pigmentation (HP:0008002)2.21711659
59Oligodactyly (hands) (HP:0001180)2.20499300
60Hypoventilation (HP:0002791)2.18217567
61Increased corneal curvature (HP:0100692)2.17601543
62Keratoconus (HP:0000563)2.17601543
63Neurofibrillary tangles (HP:0002185)2.16483409
64Spastic gait (HP:0002064)2.16424181
65Dysmetria (HP:0001310)2.14770222
66Nephrogenic diabetes insipidus (HP:0009806)2.14624863
67Hemiparesis (HP:0001269)2.13100146
68Alacrima (HP:0000522)2.12915392
69Polyphagia (HP:0002591)2.11971251
70Truncal ataxia (HP:0002078)2.08722637
71Visual hallucinations (HP:0002367)2.08620584
72Neoplasm of the heart (HP:0100544)2.08382337
73Dysdiadochokinesis (HP:0002075)2.05908099
74Glomerulosclerosis (HP:0000096)2.05712855
75Cupped ear (HP:0000378)2.05645935
76Abnormal eating behavior (HP:0100738)2.04782951
77Aplasia/Hypoplasia of the brainstem (HP:0007362)2.04637773
78Hypoplasia of the brainstem (HP:0002365)2.04637773
79Optic nerve hypoplasia (HP:0000609)2.03224660
80Poor eye contact (HP:0000817)2.03174553
81Hypsarrhythmia (HP:0002521)2.02102694
82Abnormality of the pubic bones (HP:0003172)2.01721348
83Abnormality of salivation (HP:0100755)2.01560622
84Retinal dysplasia (HP:0007973)2.01060570
85Renal cortical cysts (HP:0000803)2.00927622
86Thickened helices (HP:0000391)1.97636098
87Septo-optic dysplasia (HP:0100842)1.96573375
88Amblyopia (HP:0000646)1.96399437
89Shawl scrotum (HP:0000049)1.95682527
90Genetic anticipation (HP:0003743)1.94770652
91Pheochromocytoma (HP:0002666)1.94627430
92Bony spicule pigmentary retinopathy (HP:0007737)1.94314276
93Prolonged QT interval (HP:0001657)1.94282743
94Genital tract atresia (HP:0001827)1.93026840
95Urinary bladder sphincter dysfunction (HP:0002839)1.92178635
96Abnormality of the parietal bone (HP:0002696)1.92172455
97Tented upper lip vermilion (HP:0010804)1.92130050
98Pendular nystagmus (HP:0012043)1.91960911
99Humeroradial synostosis (HP:0003041)1.91686733
100Synostosis involving the elbow (HP:0003938)1.91686733
101Tubulointerstitial nephritis (HP:0001970)1.89644044
102Stage 5 chronic kidney disease (HP:0003774)1.88733087
103Esotropia (HP:0000565)1.88598175
104High anterior hairline (HP:0009890)1.87848869
105Vaginal atresia (HP:0000148)1.87388287
106Agitation (HP:0000713)1.85329155
107Impaired social interactions (HP:0000735)1.85151417
108Abnormal social behavior (HP:0012433)1.85151417
109Impaired vibration sensation in the lower limbs (HP:0002166)1.84223280
110Narrow nasal bridge (HP:0000446)1.82793424
111Labial hypoplasia (HP:0000066)1.82734146
112Onion bulb formation (HP:0003383)1.82596468
113Anteriorly placed anus (HP:0001545)1.82387417
114Widely spaced teeth (HP:0000687)1.82269303
115Anencephaly (HP:0002323)1.82044773
116Poor coordination (HP:0002370)1.81152063
117Decreased lacrimation (HP:0000633)1.80713607
118Abolished electroretinogram (ERG) (HP:0000550)1.80706724
119Intention tremor (HP:0002080)1.80395121
120Anophthalmia (HP:0000528)1.79833249
121Abnormal pancreas size (HP:0012094)1.79667398
122Type II lissencephaly (HP:0007260)1.79302739
123Inability to walk (HP:0002540)1.79166735
124Lower limb muscle weakness (HP:0007340)1.79099356
125Abnormality of the labia minora (HP:0012880)1.78670028
126Gait imbalance (HP:0002141)1.78220915
127Specific learning disability (HP:0001328)1.77122627
128Neoplasm of the adrenal cortex (HP:0100641)1.76840668
129Narrow forehead (HP:0000341)1.76034038
130Inappropriate behavior (HP:0000719)1.76016885
131Fetal akinesia sequence (HP:0001989)1.75768590
132Abnormality of the renal cortex (HP:0011035)1.75535743
133Epileptiform EEG discharges (HP:0011182)1.74719232
134Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.74485635
135Sensory axonal neuropathy (HP:0003390)1.74291226
136Hyperthyroidism (HP:0000836)1.73954189
137Intellectual disability, moderate (HP:0002342)1.73125434
138Decreased central vision (HP:0007663)1.72660277
139Mesangial abnormality (HP:0001966)1.72153017
140Aplasia/Hypoplasia of the sternum (HP:0006714)1.72130207
141Ulnar claw (HP:0001178)1.71753543
142Anxiety (HP:0000739)1.71400895
143Increased circulating renin level (HP:0000848)1.70997489
144Colon cancer (HP:0003003)1.70713458
145Chorioretinal atrophy (HP:0000533)1.70629505
146Limb dystonia (HP:0002451)1.70438780
147Rapidly progressive (HP:0003678)1.69762204
148Volvulus (HP:0002580)1.69285849
149Absent septum pellucidum (HP:0001331)1.69052116
150Chin dimple (HP:0010751)1.68953433
151Depression (HP:0000716)1.68833314
152Polymicrogyria (HP:0002126)1.68044382
153Broad metatarsal (HP:0001783)1.67302379
154Cystic liver disease (HP:0006706)1.67258023
155Micropenis (HP:0000054)1.67212960
156Papillary thyroid carcinoma (HP:0002895)1.66783852
157Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.66658425
158Steppage gait (HP:0003376)1.66481834
159Hypoplasia of the corpus callosum (HP:0002079)1.66364522
160EEG with generalized epileptiform discharges (HP:0011198)1.65937801
161Megalencephaly (HP:0001355)1.65047650
162Abnormal hair whorl (HP:0010721)1.65034075
163Gastroesophageal reflux (HP:0002020)1.64977458
164Urinary urgency (HP:0000012)1.64632949
165Nonprogressive disorder (HP:0003680)1.64166305

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.76592239
2EPHA43.39372081
3MARK13.04536401
4CASK3.02109007
5FRK2.95935720
6STK392.64741631
7MAP3K42.40354871
8OXSR12.24896983
9NTRK12.15274818
10PAK62.12801140
11NTRK22.06184699
12MAP3K91.95858552
13TNIK1.91694223
14MAP2K71.89241450
15PRPF4B1.75191857
16MINK11.75097397
17MAPK131.73317112
18FGFR21.73157867
19PNCK1.63971739
20EPHB21.63083172
21KSR11.56682517
22WNK41.53053950
23SGK4941.42388458
24SGK2231.42388458
25BCR1.35686991
26UHMK11.34748590
27CDK51.34706186
28WNK11.31477275
29CAMK2B1.24337125
30PAK31.23002563
31PKN11.21850750
32ADRBK21.21423153
33DYRK31.20499403
34CAMK1G1.17767704
35PLK21.16487159
36PHKG21.07879080
37PHKG11.07879080
38MARK21.07038575
39NLK1.05939860
40KSR21.04771177
41MAP2K41.03969923
42DAPK21.03218315
43CAMK2A1.02162622
44CDK190.97777448
45AKT30.95625750
46PRKCE0.94409153
47SGK20.93760964
48TIE10.93014278
49EPHB10.91775331
50CDK140.90747568
51CSNK1G20.90196466
52SIK20.88145026
53CDK180.87161845
54IRAK20.86095337
55CDK150.83308372
56DYRK1A0.82986318
57CAMKK20.82723104
58INSRR0.82644816
59MKNK20.82445521
60GRK50.82008935
61FES0.81351723
62TYRO30.79706656
63FER0.79610452
64PRKCG0.78613084
65PRKD30.78217994
66ROCK20.77405205
67WNK30.77178671
68MAP4K20.77030867
69NEK60.75616652
70CSNK1A1L0.75562052
71PRKCZ0.74995415
72CAMK2D0.73608791
73DYRK20.71826911
74CDK11A0.71087166
75EPHA30.70970372
76CDK30.70916258
77CAMK1D0.70742475
78SGK10.69277570
79SIK30.67251854
80MAPKAPK50.66791134
81CAMK10.66614102
82TRIM280.66442367
83LATS20.66138753
84SGK30.65261539
85PRKCH0.64528955
86ROCK10.64523631
87CAMKK10.64214547
88STK110.61050516
89STK380.60976452
90ERBB30.59672834
91CSNK1D0.56611118
92CSNK1G30.56427114
93YES10.55447749
94DMPK0.54458756
95DDR20.54235278
96FYN0.54048578
97ICK0.53354125
98RET0.53256128
99PKN20.52530282
100BMPR1B0.52280625
101LATS10.51506013
102CAMK2G0.51272742
103CSNK1G10.50938448
104PTK2B0.50820732
105MUSK0.50130358
106ERBB20.49107725
107ADRBK10.47775109
108BMPR20.47069849
109PRKG10.46875671
110MAP3K20.46617154
111MAP2K10.46218322
112MAP3K60.45928024
113PINK10.45550751
114PRKACA0.45280981
115FGR0.44596459
116MAPK100.44318178
117DYRK1B0.41511729
118TGFBR10.40664926
119CSNK1E0.40019893
120GRK10.39061290
121MAPK80.36365215
122PRKAA10.34719865
123RPS6KA30.34639402
124NUAK10.34346998
125MKNK10.32839173
126CAMK40.31622476
127CSNK1A10.30280342
128GSK3B0.29297824
129MAPK90.28234200
130RPS6KB10.28100574
131PRKACB0.27578636
132RPS6KA20.27307652
133TAOK30.25814007
134PIK3CA0.25722999

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.37970324
2GABAergic synapse_Homo sapiens_hsa047272.51363388
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.49195243
4Morphine addiction_Homo sapiens_hsa050322.47928197
5Synaptic vesicle cycle_Homo sapiens_hsa047212.39570392
6Circadian entrainment_Homo sapiens_hsa047132.35921015
7Glutamatergic synapse_Homo sapiens_hsa047242.28786818
8Olfactory transduction_Homo sapiens_hsa047402.16117542
9Axon guidance_Homo sapiens_hsa043602.12027665
10Dopaminergic synapse_Homo sapiens_hsa047281.93002175
11Serotonergic synapse_Homo sapiens_hsa047261.88304380
12Amphetamine addiction_Homo sapiens_hsa050311.85367449
13Cholinergic synapse_Homo sapiens_hsa047251.80129057
14Long-term potentiation_Homo sapiens_hsa047201.80080779
15Taste transduction_Homo sapiens_hsa047421.75632181
16Salivary secretion_Homo sapiens_hsa049701.74325614
17Phototransduction_Homo sapiens_hsa047441.72019506
18Cocaine addiction_Homo sapiens_hsa050301.69596454
19Renin secretion_Homo sapiens_hsa049241.63551132
20Long-term depression_Homo sapiens_hsa047301.62616335
21Insulin secretion_Homo sapiens_hsa049111.57566042
22Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.53222325
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.49879264
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46475788
25Oxytocin signaling pathway_Homo sapiens_hsa049211.41306701
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39243464
27Gastric acid secretion_Homo sapiens_hsa049711.38674213
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.37802751
29Calcium signaling pathway_Homo sapiens_hsa040201.35964616
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33542313
31Gap junction_Homo sapiens_hsa045401.33069594
32Dilated cardiomyopathy_Homo sapiens_hsa054141.32463500
33cAMP signaling pathway_Homo sapiens_hsa040241.29466885
34Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.28632463
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.26617030
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23922145
37Butanoate metabolism_Homo sapiens_hsa006501.22448003
38GnRH signaling pathway_Homo sapiens_hsa049121.17960862
39ErbB signaling pathway_Homo sapiens_hsa040121.11915338
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09604243
41Vascular smooth muscle contraction_Homo sapiens_hsa042701.09537394
42Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.08988397
43Collecting duct acid secretion_Homo sapiens_hsa049661.08879056
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.05549602
45Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.02046775
46cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99322767
47Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.97821381
48Hedgehog signaling pathway_Homo sapiens_hsa043400.97814508
49Melanogenesis_Homo sapiens_hsa049160.97099323
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.97015390
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.96003175
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.92745712
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.92726018
54Ras signaling pathway_Homo sapiens_hsa040140.92676327
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.92582304
56Cardiac muscle contraction_Homo sapiens_hsa042600.91750688
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91203459
58Dorso-ventral axis formation_Homo sapiens_hsa043200.89386981
59ECM-receptor interaction_Homo sapiens_hsa045120.89151607
60Ether lipid metabolism_Homo sapiens_hsa005650.88160637
61Glioma_Homo sapiens_hsa052140.88144246
62Renal cell carcinoma_Homo sapiens_hsa052110.84432964
63Rap1 signaling pathway_Homo sapiens_hsa040150.84255257
64Wnt signaling pathway_Homo sapiens_hsa043100.84028489
65Ovarian steroidogenesis_Homo sapiens_hsa049130.83852898
66Vibrio cholerae infection_Homo sapiens_hsa051100.83631549
67Type II diabetes mellitus_Homo sapiens_hsa049300.81903673
68MAPK signaling pathway_Homo sapiens_hsa040100.80728113
69Estrogen signaling pathway_Homo sapiens_hsa049150.79320712
70Choline metabolism in cancer_Homo sapiens_hsa052310.76357381
71Circadian rhythm_Homo sapiens_hsa047100.73268332
72Nitrogen metabolism_Homo sapiens_hsa009100.70258530
73Parkinsons disease_Homo sapiens_hsa050120.69238895
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69145446
75Pancreatic secretion_Homo sapiens_hsa049720.68467036
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65674540
77Alzheimers disease_Homo sapiens_hsa050100.65451338
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64116598
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63107567
80Melanoma_Homo sapiens_hsa052180.62460022
81Basal cell carcinoma_Homo sapiens_hsa052170.62091013
82Oxidative phosphorylation_Homo sapiens_hsa001900.59251611
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58841773
84Propanoate metabolism_Homo sapiens_hsa006400.57587925
85Thyroid hormone synthesis_Homo sapiens_hsa049180.57308573
86Focal adhesion_Homo sapiens_hsa045100.56875511
87Alcoholism_Homo sapiens_hsa050340.56501826
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.55412888
89Adherens junction_Homo sapiens_hsa045200.55333757
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.54473039
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53841849
92Endocytosis_Homo sapiens_hsa041440.53670177
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.53478468
94Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53040779
95Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52036497
96Inositol phosphate metabolism_Homo sapiens_hsa005620.51667775
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50783551
98Hippo signaling pathway_Homo sapiens_hsa043900.50416199
99Oocyte meiosis_Homo sapiens_hsa041140.50276205
100Steroid biosynthesis_Homo sapiens_hsa001000.49649319
101Tight junction_Homo sapiens_hsa045300.49532962
102Regulation of autophagy_Homo sapiens_hsa041400.48704846
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48274895
104TGF-beta signaling pathway_Homo sapiens_hsa043500.47882533
105alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46173234
106VEGF signaling pathway_Homo sapiens_hsa043700.45939690
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45669709
108Basal transcription factors_Homo sapiens_hsa030220.45491474
109ABC transporters_Homo sapiens_hsa020100.45395208
110Linoleic acid metabolism_Homo sapiens_hsa005910.44762316
111Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42877735
112AMPK signaling pathway_Homo sapiens_hsa041520.42756581
113Amoebiasis_Homo sapiens_hsa051460.42575470
114Bile secretion_Homo sapiens_hsa049760.42349035
115Huntingtons disease_Homo sapiens_hsa050160.42067183
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41665185
117Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.41521880
118Retinol metabolism_Homo sapiens_hsa008300.41174913
119Endometrial cancer_Homo sapiens_hsa052130.40130079
120Colorectal cancer_Homo sapiens_hsa052100.39997336
121SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39969291
122Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39793009
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.39746056
124Sphingolipid metabolism_Homo sapiens_hsa006000.39267232
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.36290398
126Pathways in cancer_Homo sapiens_hsa052000.36259138

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