Rank | Gene Set | Z-score |
---|---|---|
1 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.62850341 |
2 | neural tube formation (GO:0001841) | 4.84397789 |
3 | nucleobase catabolic process (GO:0046113) | 4.33493017 |
4 | neuron cell-cell adhesion (GO:0007158) | 4.22709231 |
5 | presynaptic membrane assembly (GO:0097105) | 4.08586942 |
6 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.87355813 |
7 | postsynaptic membrane organization (GO:0001941) | 3.84912863 |
8 | olfactory bulb development (GO:0021772) | 3.83594537 |
9 | mRNA splice site selection (GO:0006376) | 3.82074118 |
10 | axonal fasciculation (GO:0007413) | 3.81133886 |
11 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.79382710 |
12 | neuron recognition (GO:0008038) | 3.78818376 |
13 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.76916634 |
14 | somite development (GO:0061053) | 3.69341218 |
15 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.64949834 |
16 | glutamate receptor signaling pathway (GO:0007215) | 3.62550240 |
17 | presynaptic membrane organization (GO:0097090) | 3.60534946 |
18 | protein localization to synapse (GO:0035418) | 3.57774888 |
19 | sympathetic nervous system development (GO:0048485) | 3.56582807 |
20 | forebrain neuron differentiation (GO:0021879) | 3.52040883 |
21 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.48171945 |
22 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.48171945 |
23 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.48171945 |
24 | vocalization behavior (GO:0071625) | 3.45174010 |
25 | spinal cord development (GO:0021510) | 3.43652755 |
26 | retinal ganglion cell axon guidance (GO:0031290) | 3.43178166 |
27 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.42847934 |
28 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.41720642 |
29 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.40820641 |
30 | intraciliary transport (GO:0042073) | 3.36426135 |
31 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.34411610 |
32 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.34154285 |
33 | histone H3-K4 trimethylation (GO:0080182) | 3.33445842 |
34 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.30575851 |
35 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.29244380 |
36 | synaptic transmission, glutamatergic (GO:0035249) | 3.29037279 |
37 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.26745376 |
38 | pre-miRNA processing (GO:0031054) | 3.25884704 |
39 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.21250545 |
40 | regulation of development, heterochronic (GO:0040034) | 3.21116934 |
41 | locomotory exploration behavior (GO:0035641) | 3.20745377 |
42 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.17193877 |
43 | DNA double-strand break processing (GO:0000729) | 3.10883250 |
44 | dendritic spine morphogenesis (GO:0060997) | 3.10158011 |
45 | regulation of respiratory system process (GO:0044065) | 3.08504436 |
46 | positive regulation of synapse assembly (GO:0051965) | 3.04326180 |
47 | regulation of timing of cell differentiation (GO:0048505) | 3.03137569 |
48 | response to pheromone (GO:0019236) | 3.02924153 |
49 | epithelial cilium movement (GO:0003351) | 3.02147267 |
50 | central nervous system neuron axonogenesis (GO:0021955) | 3.01604668 |
51 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.01179667 |
52 | neuron-neuron synaptic transmission (GO:0007270) | 2.96886894 |
53 | dendrite morphogenesis (GO:0048813) | 2.94946847 |
54 | exploration behavior (GO:0035640) | 2.94196593 |
55 | resolution of meiotic recombination intermediates (GO:0000712) | 2.92389323 |
56 | transmission of nerve impulse (GO:0019226) | 2.88950176 |
57 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.86392541 |
58 | nonmotile primary cilium assembly (GO:0035058) | 2.82827496 |
59 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.82794771 |
60 | spinal cord motor neuron differentiation (GO:0021522) | 2.82205981 |
61 | gastrulation with mouth forming second (GO:0001702) | 2.82165697 |
62 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.81380771 |
63 | protein localization to cilium (GO:0061512) | 2.80814660 |
64 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 2.78438989 |
65 | regulation of synapse assembly (GO:0051963) | 2.77354071 |
66 | regulation of respiratory gaseous exchange (GO:0043576) | 2.77034380 |
67 | layer formation in cerebral cortex (GO:0021819) | 2.76355173 |
68 | negative regulation of DNA recombination (GO:0045910) | 2.75868397 |
69 | startle response (GO:0001964) | 2.74957029 |
70 | microtubule anchoring (GO:0034453) | 2.74753694 |
71 | cornea development in camera-type eye (GO:0061303) | 2.74704321 |
72 | establishment of nucleus localization (GO:0040023) | 2.73933343 |
73 | replication fork processing (GO:0031297) | 2.73011932 |
74 | cerebral cortex cell migration (GO:0021795) | 2.72675192 |
75 | cell differentiation in spinal cord (GO:0021515) | 2.72162088 |
76 | synaptic vesicle exocytosis (GO:0016079) | 2.72005708 |
77 | centriole replication (GO:0007099) | 2.71107131 |
78 | neuronal stem cell maintenance (GO:0097150) | 2.69471368 |
79 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.68793059 |
80 | DNA damage response, detection of DNA damage (GO:0042769) | 2.68571876 |
81 | otic vesicle formation (GO:0030916) | 2.68381964 |
82 | long-term memory (GO:0007616) | 2.68227116 |
83 | DNA topological change (GO:0006265) | 2.67994279 |
84 | dendrite development (GO:0016358) | 2.67669457 |
85 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.67432457 |
86 | appendage development (GO:0048736) | 2.67081393 |
87 | limb development (GO:0060173) | 2.67081393 |
88 | cerebellum development (GO:0021549) | 2.66826081 |
89 | positive regulation of synapse maturation (GO:0090129) | 2.64657566 |
90 | neuron fate determination (GO:0048664) | 2.64242875 |
91 | behavioral response to ethanol (GO:0048149) | 2.62484148 |
92 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.61958850 |
93 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.61531615 |
94 | microtubule depolymerization (GO:0007019) | 2.61526546 |
95 | histone H2A acetylation (GO:0043968) | 2.61209275 |
96 | cilium organization (GO:0044782) | 2.60942637 |
97 | limb bud formation (GO:0060174) | 2.60886736 |
98 | cilium assembly (GO:0042384) | 2.60537819 |
99 | negative regulation of axon extension (GO:0030517) | 2.60428909 |
100 | innervation (GO:0060384) | 2.60270436 |
101 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.60224746 |
102 | behavioral defense response (GO:0002209) | 2.59142625 |
103 | behavioral fear response (GO:0001662) | 2.59142625 |
104 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.58659595 |
105 | regulation of growth hormone secretion (GO:0060123) | 2.57045428 |
106 | synapse assembly (GO:0007416) | 2.56965132 |
107 | regulation of synapse maturation (GO:0090128) | 2.56433587 |
108 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.55999883 |
109 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.55892932 |
110 | cilium movement (GO:0003341) | 2.55703980 |
111 | cardiac ventricle formation (GO:0003211) | 2.53811782 |
112 | head development (GO:0060322) | 2.53810736 |
113 | regulation of postsynaptic membrane potential (GO:0060078) | 2.52453278 |
114 | regulation of synapse organization (GO:0050807) | 2.50665969 |
115 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.50525460 |
116 | spinal cord association neuron differentiation (GO:0021527) | 2.50510720 |
117 | dentate gyrus development (GO:0021542) | 2.49936589 |
118 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.49060489 |
119 | mechanosensory behavior (GO:0007638) | 2.48350597 |
120 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.48089803 |
121 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.47766121 |
122 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.47573857 |
123 | cochlea development (GO:0090102) | 2.47165897 |
124 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.46973825 |
125 | kinetochore assembly (GO:0051382) | 2.46340616 |
126 | pancreas development (GO:0031016) | 2.46074292 |
127 | cilium morphogenesis (GO:0060271) | 2.45201506 |
128 | neuronal action potential propagation (GO:0019227) | 2.45063466 |
129 | fear response (GO:0042596) | 2.45047922 |
130 | regulation of collateral sprouting (GO:0048670) | 2.44753781 |
131 | microtubule polymerization or depolymerization (GO:0031109) | 2.44585132 |
132 | negative regulation of axon guidance (GO:1902668) | 2.44444382 |
133 | establishment of mitochondrion localization (GO:0051654) | 2.44120365 |
134 | histone H3-K9 methylation (GO:0051567) | 2.42687608 |
135 | behavioral response to nicotine (GO:0035095) | 2.42219305 |
136 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.41446715 |
137 | cranial nerve structural organization (GO:0021604) | 2.40982304 |
138 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.40907319 |
139 | synaptic vesicle endocytosis (GO:0048488) | 2.39982316 |
140 | regulation of telomere maintenance (GO:0032204) | 2.39559716 |
141 | cranial nerve morphogenesis (GO:0021602) | 2.39420013 |
142 | lateral sprouting from an epithelium (GO:0060601) | 2.39094526 |
143 | embryonic epithelial tube formation (GO:0001838) | 2.39086181 |
144 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.39070446 |
145 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.38595116 |
146 | positive regulation of dendritic spine development (GO:0060999) | 2.38019319 |
147 | neuronal ion channel clustering (GO:0045161) | 2.37811028 |
148 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.37609650 |
149 | hippocampus development (GO:0021766) | 2.37575037 |
150 | ncRNA catabolic process (GO:0034661) | 2.37298483 |
151 | cardiac chamber formation (GO:0003207) | 2.36816278 |
152 | cell migration in hindbrain (GO:0021535) | 2.36586397 |
153 | regulation of axon guidance (GO:1902667) | 2.35969915 |
154 | kidney morphogenesis (GO:0060993) | 2.35817063 |
155 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.34568432 |
156 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.34164877 |
157 | cell differentiation involved in kidney development (GO:0061005) | 2.34066023 |
158 | peptidyl-lysine trimethylation (GO:0018023) | 2.33874615 |
159 | hindbrain development (GO:0030902) | 2.33517187 |
160 | response to histamine (GO:0034776) | 2.32976196 |
161 | * regulation of mRNA splicing, via spliceosome (GO:0048024) | 2.32881355 |
162 | learning (GO:0007612) | 2.32478278 |
163 | glial cell proliferation (GO:0014009) | 2.31808826 |
164 | auditory behavior (GO:0031223) | 2.29684741 |
165 | long-term synaptic potentiation (GO:0060291) | 2.29596419 |
166 | positive regulation of membrane potential (GO:0045838) | 2.28499123 |
167 | mitotic sister chromatid cohesion (GO:0007064) | 2.27707278 |
168 | righting reflex (GO:0060013) | 2.24515046 |
169 | membrane hyperpolarization (GO:0060081) | 2.23902159 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.79308227 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.03527899 |
3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.87744721 |
4 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.83500131 |
5 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.61742294 |
6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.56572222 |
7 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.50492547 |
8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.42114398 |
9 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.41688357 |
10 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.41531017 |
11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.34310825 |
12 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.27413833 |
13 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.26666381 |
14 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.26666381 |
15 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.25085073 |
16 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.20808611 |
17 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.15388926 |
18 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.13087717 |
19 | FUS_26573619_Chip-Seq_HEK293_Human | 2.12601251 |
20 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.12364333 |
21 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.04282084 |
22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.03906076 |
23 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.01215762 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.99625752 |
25 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.97681447 |
26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.96761046 |
27 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.95599892 |
28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.94830546 |
29 | VDR_22108803_ChIP-Seq_LS180_Human | 1.93221832 |
30 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.92329467 |
31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.90023483 |
32 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.86821147 |
33 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.86277933 |
34 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.85526474 |
35 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.84396257 |
36 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.82976904 |
37 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.81024177 |
38 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.78597123 |
39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.76624777 |
40 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.76171648 |
41 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.72149565 |
42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.70273834 |
43 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.66295339 |
44 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.58287668 |
45 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.56773822 |
46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.56079888 |
47 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.56029690 |
48 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.55066767 |
49 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.54425396 |
50 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.54028573 |
51 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.53403410 |
52 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.51410033 |
53 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.50863246 |
54 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.49579915 |
55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.49273773 |
56 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.43504098 |
57 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.40887723 |
58 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.39722956 |
59 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39722956 |
60 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.38798159 |
61 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.37479622 |
62 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.36956098 |
63 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.32452220 |
64 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.31716336 |
65 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.31269500 |
66 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.29632423 |
67 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.29632423 |
68 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.29209148 |
69 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.28041122 |
70 | AR_25329375_ChIP-Seq_VCAP_Human | 1.27603076 |
71 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.27467600 |
72 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27461057 |
73 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.26557976 |
74 | STAT3_23295773_ChIP-Seq_U87_Human | 1.26515369 |
75 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25944801 |
76 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.24808948 |
77 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.24719572 |
78 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.24397391 |
79 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.23897117 |
80 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.23375401 |
81 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.23196985 |
82 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.23130118 |
83 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.22817792 |
84 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.22769607 |
85 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.22440068 |
86 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.22133804 |
87 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.21731058 |
88 | TCF4_23295773_ChIP-Seq_U87_Human | 1.20543496 |
89 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19801829 |
90 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18510041 |
91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17466807 |
92 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.17300637 |
93 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.17181367 |
94 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.16999714 |
95 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.15941618 |
96 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.15262055 |
97 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.15011617 |
98 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14971884 |
99 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.14886164 |
100 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.14353657 |
101 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.13840821 |
102 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.13820379 |
103 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.13482492 |
104 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.13399168 |
105 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.13165857 |
106 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12059456 |
107 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.11784531 |
108 | TP53_16413492_ChIP-PET_HCT116_Human | 1.11357520 |
109 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.10454977 |
110 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.10292776 |
111 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.10114449 |
112 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.08542558 |
113 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.08494393 |
114 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.06630829 |
115 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.06619233 |
116 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.06427774 |
117 | AR_19668381_ChIP-Seq_PC3_Human | 1.06078358 |
118 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.06040784 |
119 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05931797 |
120 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.05435672 |
121 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.04981961 |
122 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.04774837 |
123 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.03662040 |
124 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.03631172 |
125 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02525452 |
126 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01946594 |
127 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.00737048 |
128 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.00154425 |
129 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.99633763 |
130 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.99240638 |
131 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.98128259 |
132 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.97180626 |
133 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.97164390 |
134 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.95050194 |
135 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.94555238 |
136 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.94149992 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 3.79830272 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.38607734 |
3 | MP0005423_abnormal_somatic_nervous | 2.83687421 |
4 | MP0003635_abnormal_synaptic_transmissio | 2.65594562 |
5 | MP0006292_abnormal_olfactory_placode | 2.64024263 |
6 | MP0003787_abnormal_imprinting | 2.58199504 |
7 | MP0008877_abnormal_DNA_methylation | 2.45181297 |
8 | MP0000778_abnormal_nervous_system | 2.43533101 |
9 | MP0001188_hyperpigmentation | 2.25830338 |
10 | MP0003122_maternal_imprinting | 2.25055693 |
11 | MP0002063_abnormal_learning/memory/cond | 2.24521893 |
12 | MP0009745_abnormal_behavioral_response | 2.21630946 |
13 | MP0004133_heterotaxia | 2.19446100 |
14 | MP0002572_abnormal_emotion/affect_behav | 2.05392655 |
15 | MP0003121_genomic_imprinting | 2.04884734 |
16 | MP0001486_abnormal_startle_reflex | 2.01343941 |
17 | MP0004270_analgesia | 2.00814161 |
18 | MP0001293_anophthalmia | 1.97379659 |
19 | MP0005409_darkened_coat_color | 1.94988476 |
20 | MP0002064_seizures | 1.87052234 |
21 | MP0002184_abnormal_innervation | 1.83657516 |
22 | MP0001968_abnormal_touch/_nociception | 1.82799206 |
23 | MP0006276_abnormal_autonomic_nervous | 1.74926190 |
24 | MP0002557_abnormal_social/conspecific_i | 1.72565758 |
25 | MP0000569_abnormal_digit_pigmentation | 1.72420799 |
26 | MP0000631_abnormal_neuroendocrine_gland | 1.71636370 |
27 | MP0002272_abnormal_nervous_system | 1.71251858 |
28 | MP0002067_abnormal_sensory_capabilities | 1.68559543 |
29 | MP0002938_white_spotting | 1.64450049 |
30 | MP0002822_catalepsy | 1.64359833 |
31 | MP0005248_abnormal_Harderian_gland | 1.62105045 |
32 | MP0005646_abnormal_pituitary_gland | 1.61902795 |
33 | MP0001529_abnormal_vocalization | 1.59498883 |
34 | MP0008057_abnormal_DNA_replication | 1.59385699 |
35 | MP0006072_abnormal_retinal_apoptosis | 1.59295748 |
36 | MP0009046_muscle_twitch | 1.59273149 |
37 | MP0004885_abnormal_endolymph | 1.57277946 |
38 | MP0001286_abnormal_eye_development | 1.56645043 |
39 | MP0001984_abnormal_olfaction | 1.54967910 |
40 | MP0002734_abnormal_mechanical_nocicepti | 1.54581597 |
41 | MP0002102_abnormal_ear_morphology | 1.51587782 |
42 | MP0003119_abnormal_digestive_system | 1.50930048 |
43 | MP0005645_abnormal_hypothalamus_physiol | 1.49308313 |
44 | MP0005394_taste/olfaction_phenotype | 1.48551453 |
45 | MP0005499_abnormal_olfactory_system | 1.48551453 |
46 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46850415 |
47 | MP0002736_abnormal_nociception_after | 1.46795278 |
48 | MP0002638_abnormal_pupillary_reflex | 1.39957505 |
49 | MP0001502_abnormal_circadian_rhythm | 1.39793419 |
50 | MP0000049_abnormal_middle_ear | 1.39690630 |
51 | MP0004924_abnormal_behavior | 1.39321800 |
52 | MP0005386_behavior/neurological_phenoty | 1.39321800 |
53 | MP0005551_abnormal_eye_electrophysiolog | 1.38406033 |
54 | MP0002735_abnormal_chemical_nociception | 1.38372942 |
55 | MP0000955_abnormal_spinal_cord | 1.35325609 |
56 | MP0002697_abnormal_eye_size | 1.33791157 |
57 | MP0008058_abnormal_DNA_repair | 1.33659365 |
58 | MP0002882_abnormal_neuron_morphology | 1.33296379 |
59 | MP0008789_abnormal_olfactory_epithelium | 1.32476124 |
60 | MP0002152_abnormal_brain_morphology | 1.23047027 |
61 | MP0003938_abnormal_ear_development | 1.22953170 |
62 | MP0005253_abnormal_eye_physiology | 1.22825672 |
63 | MP0008569_lethality_at_weaning | 1.21673904 |
64 | MP0003385_abnormal_body_wall | 1.19278434 |
65 | MP0003861_abnormal_nervous_system | 1.19068838 |
66 | MP0002751_abnormal_autonomic_nervous | 1.18584876 |
67 | MP0001501_abnormal_sleep_pattern | 1.16856578 |
68 | MP0002653_abnormal_ependyma_morphology | 1.15906776 |
69 | MP0000566_synostosis | 1.15591942 |
70 | MP0004811_abnormal_neuron_physiology | 1.14513911 |
71 | MP0005367_renal/urinary_system_phenotyp | 1.13831649 |
72 | MP0000516_abnormal_urinary_system | 1.13831649 |
73 | MP0000647_abnormal_sebaceous_gland | 1.12407455 |
74 | MP0001485_abnormal_pinna_reflex | 1.11763740 |
75 | MP0001440_abnormal_grooming_behavior | 1.06941738 |
76 | MP0005171_absent_coat_pigmentation | 1.06518089 |
77 | MP0003890_abnormal_embryonic-extraembry | 1.06436161 |
78 | MP0008995_early_reproductive_senescence | 1.06056087 |
79 | MP0004742_abnormal_vestibular_system | 1.04605377 |
80 | MP0002752_abnormal_somatic_nervous | 1.03434122 |
81 | MP0000026_abnormal_inner_ear | 1.03344000 |
82 | MP0003123_paternal_imprinting | 1.02757224 |
83 | MP0009703_decreased_birth_body | 1.02732708 |
84 | MP0010094_abnormal_chromosome_stability | 1.01806941 |
85 | MP0002733_abnormal_thermal_nociception | 1.01074848 |
86 | MP0002234_abnormal_pharynx_morphology | 0.98638178 |
87 | MP0001970_abnormal_pain_threshold | 0.97951609 |
88 | MP0002249_abnormal_larynx_morphology | 0.96616889 |
89 | MP0002066_abnormal_motor_capabilities/c | 0.95989798 |
90 | MP0009379_abnormal_foot_pigmentation | 0.95635140 |
91 | MP0003942_abnormal_urinary_system | 0.95559354 |
92 | MP0001963_abnormal_hearing_physiology | 0.94674368 |
93 | MP0002092_abnormal_eye_morphology | 0.92939262 |
94 | MP0003937_abnormal_limbs/digits/tail_de | 0.92697054 |
95 | MP0001299_abnormal_eye_distance/ | 0.91145126 |
96 | MP0002084_abnormal_developmental_patter | 0.91121073 |
97 | MP0003755_abnormal_palate_morphology | 0.90820843 |
98 | MP0005174_abnormal_tail_pigmentation | 0.90549034 |
99 | MP0002095_abnormal_skin_pigmentation | 0.89364312 |
100 | MP0001324_abnormal_eye_pigmentation | 0.89268135 |
101 | MP0003136_yellow_coat_color | 0.88898671 |
102 | MP0009250_abnormal_appendicular_skeleto | 0.88833151 |
103 | MP0002116_abnormal_craniofacial_bone | 0.88115765 |
104 | MP0001905_abnormal_dopamine_level | 0.87982468 |
105 | MP0003935_abnormal_craniofacial_develop | 0.87599547 |
106 | MP0004142_abnormal_muscle_tone | 0.86825480 |
107 | MP0002177_abnormal_outer_ear | 0.86210469 |
108 | MP0004197_abnormal_fetal_growth/weight/ | 0.85390944 |
109 | MP0000015_abnormal_ear_pigmentation | 0.85288382 |
110 | MP0002081_perinatal_lethality | 0.83204839 |
111 | MP0004134_abnormal_chest_morphology | 0.82152177 |
112 | MP0000537_abnormal_urethra_morphology | 0.80890011 |
113 | MP0002009_preneoplasia | 0.80858328 |
114 | MP0010030_abnormal_orbit_morphology | 0.80719511 |
115 | MP0004145_abnormal_muscle_electrophysio | 0.79440478 |
116 | MP0005187_abnormal_penis_morphology | 0.78754159 |
117 | MP0003943_abnormal_hepatobiliary_system | 0.78737179 |
118 | MP0002233_abnormal_nose_morphology | 0.78466233 |
119 | MP0003195_calcinosis | 0.77580511 |
120 | MP0001346_abnormal_lacrimal_gland | 0.77240158 |
121 | MP0005391_vision/eye_phenotype | 0.76966082 |
122 | MP0003137_abnormal_impulse_conducting | 0.76204144 |
123 | MP0003878_abnormal_ear_physiology | 0.75534487 |
124 | MP0005377_hearing/vestibular/ear_phenot | 0.75534487 |
125 | MP0005195_abnormal_posterior_eye | 0.72708526 |
126 | MP0001177_atelectasis | 0.72203654 |
127 | MP0002114_abnormal_axial_skeleton | 0.72070183 |
128 | MP0010386_abnormal_urinary_bladder | 0.71731463 |
129 | MP0003315_abnormal_perineum_morphology | 0.69741286 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 3.56113650 |
2 | Epileptic encephalopathy (HP:0200134) | 3.12635871 |
3 | Abnormality of the labia minora (HP:0012880) | 3.09937257 |
4 | Febrile seizures (HP:0002373) | 3.07389500 |
5 | Protruding tongue (HP:0010808) | 2.98063306 |
6 | Pancreatic cysts (HP:0001737) | 2.82582542 |
7 | Short 4th metacarpal (HP:0010044) | 2.76627063 |
8 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.76627063 |
9 | Broad-based gait (HP:0002136) | 2.74022730 |
10 | Colon cancer (HP:0003003) | 2.73447862 |
11 | Cortical dysplasia (HP:0002539) | 2.66870536 |
12 | Progressive cerebellar ataxia (HP:0002073) | 2.61699830 |
13 | Supernumerary spleens (HP:0009799) | 2.57565521 |
14 | Abnormality of the renal medulla (HP:0100957) | 2.55549837 |
15 | Volvulus (HP:0002580) | 2.55089682 |
16 | Focal seizures (HP:0007359) | 2.54391612 |
17 | Vitreoretinal degeneration (HP:0000655) | 2.40381430 |
18 | Drooling (HP:0002307) | 2.36045236 |
19 | Excessive salivation (HP:0003781) | 2.36045236 |
20 | Abnormal lung lobation (HP:0002101) | 2.23568341 |
21 | Postaxial hand polydactyly (HP:0001162) | 2.21876272 |
22 | Postaxial foot polydactyly (HP:0001830) | 2.21537247 |
23 | Atonic seizures (HP:0010819) | 2.20703491 |
24 | Hyperventilation (HP:0002883) | 2.20561668 |
25 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.14092070 |
26 | Abnormal hair whorl (HP:0010721) | 2.14090211 |
27 | Tubulointerstitial nephritis (HP:0001970) | 2.12418283 |
28 | Tented upper lip vermilion (HP:0010804) | 2.09313850 |
29 | Septo-optic dysplasia (HP:0100842) | 2.07865046 |
30 | Bifid tongue (HP:0010297) | 2.07677498 |
31 | Abnormality of the pubic bones (HP:0003172) | 2.07539139 |
32 | Absent speech (HP:0001344) | 2.06707514 |
33 | Obsessive-compulsive behavior (HP:0000722) | 2.06453348 |
34 | Medulloblastoma (HP:0002885) | 2.04075099 |
35 | Papillary thyroid carcinoma (HP:0002895) | 2.03419770 |
36 | Exotropia (HP:0000577) | 2.02620499 |
37 | Aqueductal stenosis (HP:0002410) | 2.02099996 |
38 | Morphological abnormality of the middle ear (HP:0008609) | 2.01866317 |
39 | Cutaneous finger syndactyly (HP:0010554) | 2.00994491 |
40 | Thyroiditis (HP:0100646) | 1.99820098 |
41 | Oligodactyly (hands) (HP:0001180) | 1.99577635 |
42 | Genetic anticipation (HP:0003743) | 1.98079111 |
43 | Midline defect of the nose (HP:0004122) | 1.97852814 |
44 | Hip dysplasia (HP:0001385) | 1.95566383 |
45 | Optic nerve hypoplasia (HP:0000609) | 1.95226509 |
46 | Anencephaly (HP:0002323) | 1.94924792 |
47 | Gastrointestinal atresia (HP:0002589) | 1.94164995 |
48 | Dandy-Walker malformation (HP:0001305) | 1.92285172 |
49 | Gait imbalance (HP:0002141) | 1.91320493 |
50 | Intestinal atresia (HP:0011100) | 1.90667395 |
51 | Autism (HP:0000717) | 1.89234968 |
52 | Neoplasm of the adrenal cortex (HP:0100641) | 1.89128019 |
53 | Broad alveolar ridges (HP:0000187) | 1.88141097 |
54 | Widely spaced teeth (HP:0000687) | 1.87974896 |
55 | Cystic liver disease (HP:0006706) | 1.87934377 |
56 | Meckel diverticulum (HP:0002245) | 1.87548416 |
57 | Abnormality of the renal cortex (HP:0011035) | 1.87359525 |
58 | Cutaneous syndactyly (HP:0012725) | 1.85896017 |
59 | Gaze-evoked nystagmus (HP:0000640) | 1.85279416 |
60 | Poor coordination (HP:0002370) | 1.84732461 |
61 | Scrotal hypoplasia (HP:0000046) | 1.84451442 |
62 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.84380885 |
63 | Abnormality of the 4th metacarpal (HP:0010012) | 1.82728519 |
64 | Truncal ataxia (HP:0002078) | 1.82358939 |
65 | Renal hypoplasia (HP:0000089) | 1.82009583 |
66 | Narrow nasal bridge (HP:0000446) | 1.81870443 |
67 | Blue irides (HP:0000635) | 1.81704874 |
68 | Abnormality of the ileum (HP:0001549) | 1.81679149 |
69 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.81594069 |
70 | Medial flaring of the eyebrow (HP:0010747) | 1.81579734 |
71 | Severe visual impairment (HP:0001141) | 1.81119012 |
72 | Patellar aplasia (HP:0006443) | 1.80847307 |
73 | Anophthalmia (HP:0000528) | 1.80032391 |
74 | Micropenis (HP:0000054) | 1.79853758 |
75 | Inappropriate behavior (HP:0000719) | 1.79515244 |
76 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.79477134 |
77 | Absent eyebrow (HP:0002223) | 1.79198250 |
78 | Acute lymphatic leukemia (HP:0006721) | 1.78923851 |
79 | Abnormality of hair growth rate (HP:0011363) | 1.78156780 |
80 | Slow-growing hair (HP:0002217) | 1.78156780 |
81 | Narrow forehead (HP:0000341) | 1.77923316 |
82 | Labial hypoplasia (HP:0000066) | 1.77244985 |
83 | Stereotypic behavior (HP:0000733) | 1.76609494 |
84 | Neoplasm of the oral cavity (HP:0100649) | 1.75524558 |
85 | True hermaphroditism (HP:0010459) | 1.74302704 |
86 | Renal duplication (HP:0000075) | 1.74101359 |
87 | Absence seizures (HP:0002121) | 1.73126160 |
88 | Bilateral microphthalmos (HP:0007633) | 1.73109508 |
89 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.73040772 |
90 | Renal cortical cysts (HP:0000803) | 1.71851810 |
91 | Amyotrophic lateral sclerosis (HP:0007354) | 1.70783109 |
92 | Glioma (HP:0009733) | 1.70696257 |
93 | Severe Myopia (HP:0011003) | 1.70631871 |
94 | Embryonal renal neoplasm (HP:0011794) | 1.70582419 |
95 | Preaxial hand polydactyly (HP:0001177) | 1.70147030 |
96 | Molar tooth sign on MRI (HP:0002419) | 1.69730580 |
97 | Abnormality of midbrain morphology (HP:0002418) | 1.69730580 |
98 | Abnormal biliary tract physiology (HP:0012439) | 1.69084702 |
99 | Bile duct proliferation (HP:0001408) | 1.69084702 |
100 | Abnormality of the parietal bone (HP:0002696) | 1.68661001 |
101 | Gastroesophageal reflux (HP:0002020) | 1.68365528 |
102 | Thyroid carcinoma (HP:0002890) | 1.68265067 |
103 | Decreased lacrimation (HP:0000633) | 1.68059192 |
104 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.67881992 |
105 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.67881992 |
106 | Scanning speech (HP:0002168) | 1.67365620 |
107 | High anterior hairline (HP:0009890) | 1.67265802 |
108 | Broad foot (HP:0001769) | 1.67243613 |
109 | Short philtrum (HP:0000322) | 1.66841743 |
110 | Rhabdomyosarcoma (HP:0002859) | 1.66261465 |
111 | Growth hormone deficiency (HP:0000824) | 1.66194901 |
112 | Congenital primary aphakia (HP:0007707) | 1.65971174 |
113 | Specific learning disability (HP:0001328) | 1.65929271 |
114 | Hyperglycinemia (HP:0002154) | 1.65248612 |
115 | Deeply set eye (HP:0000490) | 1.65139362 |
116 | Hemiparesis (HP:0001269) | 1.64706687 |
117 | Abnormality of chromosome stability (HP:0003220) | 1.64589124 |
118 | Abnormality of the parathyroid morphology (HP:0011766) | 1.63884208 |
119 | Hepatoblastoma (HP:0002884) | 1.63670988 |
120 | Severe combined immunodeficiency (HP:0004430) | 1.63620866 |
121 | Abolished electroretinogram (ERG) (HP:0000550) | 1.63503253 |
122 | Nephrogenic diabetes insipidus (HP:0009806) | 1.63417190 |
123 | Gonadotropin excess (HP:0000837) | 1.63240509 |
124 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.63212916 |
125 | Visual hallucinations (HP:0002367) | 1.61876181 |
126 | Thickened helices (HP:0000391) | 1.61793678 |
127 | Heterochromia iridis (HP:0001100) | 1.61241668 |
128 | Alacrima (HP:0000522) | 1.60892146 |
129 | Abnormality of salivation (HP:0100755) | 1.60801268 |
130 | Highly arched eyebrow (HP:0002553) | 1.58550864 |
131 | Genital tract atresia (HP:0001827) | 1.58052443 |
132 | Chronic hepatic failure (HP:0100626) | 1.57998729 |
133 | Lissencephaly (HP:0001339) | 1.57425775 |
134 | Cupped ear (HP:0000378) | 1.56471461 |
135 | Trigonocephaly (HP:0000243) | 1.56335042 |
136 | Thyroid-stimulating hormone excess (HP:0002925) | 1.56239468 |
137 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.55108194 |
138 | Increased nuchal translucency (HP:0010880) | 1.53160560 |
139 | Dialeptic seizures (HP:0011146) | 1.53154300 |
140 | Absent frontal sinuses (HP:0002688) | 1.53001585 |
141 | Vaginal atresia (HP:0000148) | 1.52020436 |
142 | Open mouth (HP:0000194) | 1.51696611 |
143 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.51665578 |
144 | Hypoplasia of the brainstem (HP:0002365) | 1.51665578 |
145 | Anteriorly placed anus (HP:0001545) | 1.51532694 |
146 | Amblyopia (HP:0000646) | 1.51170619 |
147 | Hypoplasia of the maxilla (HP:0000327) | 1.50813575 |
148 | Abnormality of the nasolacrimal system (HP:0000614) | 1.50427320 |
149 | Impaired smooth pursuit (HP:0007772) | 1.49811375 |
150 | Limb dystonia (HP:0002451) | 1.49660610 |
151 | Long nose (HP:0003189) | 1.49135237 |
152 | Elfin facies (HP:0004428) | 1.48164887 |
153 | Megalencephaly (HP:0001355) | 1.48146412 |
154 | Macroorchidism (HP:0000053) | 1.48145252 |
155 | Pancreatic fibrosis (HP:0100732) | 1.47809666 |
156 | Abnormality of the intervertebral disk (HP:0005108) | 1.47712311 |
157 | Embryonal neoplasm (HP:0002898) | 1.47268840 |
158 | Asymmetry of the thorax (HP:0001555) | 1.47025176 |
159 | Abnormality of chromosome segregation (HP:0002916) | 1.46915215 |
160 | Sacral dimple (HP:0000960) | 1.46894311 |
161 | Nephronophthisis (HP:0000090) | 1.46641584 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TNIK | 4.14506425 |
2 | MARK1 | 3.60030550 |
3 | NTRK3 | 3.58442427 |
4 | CASK | 3.37534329 |
5 | EPHA4 | 3.32244493 |
6 | MAPK13 | 2.77674236 |
7 | BRD4 | 2.20325851 |
8 | NTRK2 | 2.17995515 |
9 | SIK2 | 2.17504842 |
10 | FRK | 2.09228791 |
11 | MAP2K7 | 2.00687832 |
12 | TRIM28 | 1.97796281 |
13 | ERBB3 | 1.91563967 |
14 | MAP3K4 | 1.86623736 |
15 | MKNK2 | 1.83808543 |
16 | MKNK1 | 1.82111848 |
17 | PLK4 | 1.66609496 |
18 | PNCK | 1.62620766 |
19 | SRPK1 | 1.59950017 |
20 | UHMK1 | 1.59812512 |
21 | CDC7 | 1.58281086 |
22 | YES1 | 1.56588786 |
23 | DYRK1A | 1.51217937 |
24 | MAP4K2 | 1.43352212 |
25 | SGK2 | 1.41158202 |
26 | MINK1 | 1.37184914 |
27 | ACVR1B | 1.35683033 |
28 | CCNB1 | 1.35041475 |
29 | KSR1 | 1.30835646 |
30 | BMPR1B | 1.26637620 |
31 | CDK3 | 1.22578928 |
32 | LATS1 | 1.20738260 |
33 | EPHA3 | 1.19195175 |
34 | MAP3K12 | 1.15796856 |
35 | CAMK1G | 1.14784937 |
36 | SGK223 | 1.11029815 |
37 | SGK494 | 1.11029815 |
38 | CSNK1G2 | 1.09806361 |
39 | CSNK1A1L | 1.09165486 |
40 | FGFR2 | 1.06158745 |
41 | ZAK | 1.05476738 |
42 | PLK2 | 1.05385469 |
43 | CDK19 | 1.02522088 |
44 | CDK5 | 0.96888896 |
45 | CAMKK2 | 0.93659188 |
46 | STK39 | 0.92642267 |
47 | NLK | 0.91809186 |
48 | CSNK1G3 | 0.91207593 |
49 | RPS6KA4 | 0.91164243 |
50 | WEE1 | 0.90993220 |
51 | BRSK2 | 0.90759555 |
52 | AKT3 | 0.89785164 |
53 | MUSK | 0.89494182 |
54 | WNK3 | 0.87711211 |
55 | PINK1 | 0.83944310 |
56 | CAMK2B | 0.83153994 |
57 | OXSR1 | 0.83043008 |
58 | FES | 0.82680204 |
59 | ADRBK2 | 0.81372671 |
60 | FGFR1 | 0.80857085 |
61 | RIPK4 | 0.80177142 |
62 | STK3 | 0.79469424 |
63 | MARK2 | 0.78917860 |
64 | SGK3 | 0.78526377 |
65 | FLT3 | 0.77896336 |
66 | CAMK1 | 0.75547141 |
67 | SIK3 | 0.74022718 |
68 | SGK1 | 0.73217303 |
69 | CSNK1G1 | 0.72858899 |
70 | DYRK2 | 0.72724887 |
71 | PRPF4B | 0.71011975 |
72 | STK38L | 0.70490371 |
73 | CAMK4 | 0.69679594 |
74 | ADRBK1 | 0.68655665 |
75 | TAF1 | 0.67234631 |
76 | RPS6KA2 | 0.66923615 |
77 | MAP2K4 | 0.66392194 |
78 | MAP3K7 | 0.66310925 |
79 | CDK8 | 0.66014639 |
80 | CDC42BPA | 0.65915613 |
81 | CAMK2A | 0.64926870 |
82 | WNK1 | 0.64877319 |
83 | GRK1 | 0.64072837 |
84 | INSRR | 0.63673269 |
85 | PAK3 | 0.63561803 |
86 | PRKCG | 0.63525235 |
87 | NUAK1 | 0.62721257 |
88 | ERBB2 | 0.62277206 |
89 | ATM | 0.62207584 |
90 | MAP3K10 | 0.62047342 |
91 | DAPK2 | 0.60419114 |
92 | EIF2AK3 | 0.60404901 |
93 | PAK6 | 0.59641448 |
94 | DAPK1 | 0.58874517 |
95 | BCR | 0.58747107 |
96 | CDK18 | 0.57908553 |
97 | TTK | 0.57714263 |
98 | ATR | 0.57424081 |
99 | STK16 | 0.57255946 |
100 | PLK1 | 0.56991863 |
101 | WNK4 | 0.56121303 |
102 | TGFBR1 | 0.55951426 |
103 | DYRK3 | 0.55891838 |
104 | NEK6 | 0.54791404 |
105 | PKN1 | 0.53942627 |
106 | MAP3K6 | 0.53790819 |
107 | HIPK2 | 0.53619688 |
108 | FGFR3 | 0.53603657 |
109 | CDK15 | 0.53349024 |
110 | BRAF | 0.51377945 |
111 | EPHB2 | 0.50988257 |
112 | CDK11A | 0.49568944 |
113 | PIK3CA | 0.48915238 |
114 | CSNK1D | 0.48724803 |
115 | CDK14 | 0.48070693 |
116 | TSSK6 | 0.48065476 |
117 | CAMKK1 | 0.47844903 |
118 | MAPK9 | 0.47762277 |
119 | GSK3B | 0.46763767 |
120 | MAPK15 | 0.46462322 |
121 | PHKG1 | 0.45909020 |
122 | PHKG2 | 0.45909020 |
123 | PRKG1 | 0.44884701 |
124 | PLK3 | 0.44034794 |
125 | DYRK1B | 0.43922991 |
126 | TYRO3 | 0.43492613 |
127 | CDK1 | 0.43449371 |
128 | RPS6KB1 | 0.43142424 |
129 | CSNK1E | 0.42962914 |
130 | PRKCE | 0.41758384 |
131 | CLK1 | 0.41605673 |
132 | PASK | 0.41303686 |
133 | MAPK10 | 0.40505836 |
134 | VRK1 | 0.39899893 |
135 | RPS6KA3 | 0.39449895 |
136 | STK11 | 0.39215983 |
137 | PRKDC | 0.39194792 |
138 | MAP3K9 | 0.38879649 |
139 | BMPR2 | 0.38705787 |
140 | MAPK8 | 0.38632373 |
141 | CHEK2 | 0.33461002 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.60473086 |
2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.48984197 |
3 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.71433381 |
4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.35608751 |
5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.32263463 |
6 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.28538871 |
7 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.26844608 |
8 | Morphine addiction_Homo sapiens_hsa05032 | 2.24358220 |
9 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.15624656 |
10 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.15001143 |
11 | Long-term potentiation_Homo sapiens_hsa04720 | 2.14810187 |
12 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.07540971 |
13 | GABAergic synapse_Homo sapiens_hsa04727 | 2.05325844 |
14 | Basal transcription factors_Homo sapiens_hsa03022 | 2.04080921 |
15 | Protein export_Homo sapiens_hsa03060 | 2.03428518 |
16 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.92029906 |
17 | Taste transduction_Homo sapiens_hsa04742 | 1.86047452 |
18 | Olfactory transduction_Homo sapiens_hsa04740 | 1.83525337 |
19 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.79160759 |
20 | Axon guidance_Homo sapiens_hsa04360 | 1.69688069 |
21 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.65518520 |
22 | Long-term depression_Homo sapiens_hsa04730 | 1.63815216 |
23 | Phototransduction_Homo sapiens_hsa04744 | 1.59050121 |
24 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.55428023 |
25 | Cocaine addiction_Homo sapiens_hsa05030 | 1.51420481 |
26 | Insulin secretion_Homo sapiens_hsa04911 | 1.48785325 |
27 | Renin secretion_Homo sapiens_hsa04924 | 1.46540320 |
28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.43762331 |
29 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.43512599 |
30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.43047502 |
31 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.40869871 |
32 | Salivary secretion_Homo sapiens_hsa04970 | 1.39647510 |
33 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.38207497 |
34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.37583408 |
35 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.36667092 |
36 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.36197523 |
37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.35478976 |
38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.34053470 |
39 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.29344093 |
40 | Gap junction_Homo sapiens_hsa04540 | 1.20198760 |
41 | Melanogenesis_Homo sapiens_hsa04916 | 1.18321111 |
42 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.17517474 |
43 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.17464527 |
44 | RNA transport_Homo sapiens_hsa03013 | 1.16166475 |
45 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.16035367 |
46 | Alcoholism_Homo sapiens_hsa05034 | 1.15864687 |
47 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.15712739 |
48 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.14830478 |
49 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.10824987 |
50 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.10659683 |
51 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.05713895 |
52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.05013545 |
53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.04945348 |
54 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.04838398 |
55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.03644809 |
56 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.03504260 |
57 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00809505 |
58 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.99572457 |
59 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.98526883 |
60 | Colorectal cancer_Homo sapiens_hsa05210 | 0.98265049 |
61 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.96356281 |
62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.96055178 |
63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.94354754 |
64 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.94184979 |
65 | Lysine degradation_Homo sapiens_hsa00310 | 0.94019055 |
66 | Glioma_Homo sapiens_hsa05214 | 0.93281223 |
67 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.93115127 |
68 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.92503186 |
69 | Spliceosome_Homo sapiens_hsa03040 | 0.90640336 |
70 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.88327067 |
71 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.87867356 |
72 | Circadian rhythm_Homo sapiens_hsa04710 | 0.87210457 |
73 | Endometrial cancer_Homo sapiens_hsa05213 | 0.87073466 |
74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.86954853 |
75 | Peroxisome_Homo sapiens_hsa04146 | 0.83954980 |
76 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.82695770 |
77 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.82613364 |
78 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.78787544 |
79 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.78152045 |
80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.77062308 |
81 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.75049098 |
82 | RNA degradation_Homo sapiens_hsa03018 | 0.73842566 |
83 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.72810938 |
84 | Mismatch repair_Homo sapiens_hsa03430 | 0.72233850 |
85 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.71668913 |
86 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.71033971 |
87 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.70800251 |
88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.70715582 |
89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.70607720 |
90 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.70178121 |
91 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.69371758 |
92 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.69193426 |
93 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.67621526 |
94 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.67094910 |
95 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.65477093 |
96 | Adherens junction_Homo sapiens_hsa04520 | 0.65412231 |
97 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65244784 |
98 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.64039681 |
99 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.62862154 |
100 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.62819315 |
101 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.62417357 |
102 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.62383968 |
103 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.61470098 |
104 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.60986232 |
105 | ABC transporters_Homo sapiens_hsa02010 | 0.60614970 |
106 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60436004 |
107 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.57660166 |
108 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.57341215 |
109 | Retinol metabolism_Homo sapiens_hsa00830 | 0.57061866 |
110 | Tight junction_Homo sapiens_hsa04530 | 0.57008597 |
111 | Cell cycle_Homo sapiens_hsa04110 | 0.56632194 |
112 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.56114937 |
113 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55033387 |
114 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.55033027 |
115 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.54186542 |
116 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.53980366 |
117 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.53155673 |
118 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50911301 |
119 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.50893317 |
120 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.49984635 |
121 | Melanoma_Homo sapiens_hsa05218 | 0.49957223 |
122 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.48408741 |
123 | Homologous recombination_Homo sapiens_hsa03440 | 0.47882612 |
124 | Prostate cancer_Homo sapiens_hsa05215 | 0.47601160 |
125 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.47242660 |
126 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.46567396 |
127 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.46395096 |
128 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.45969243 |
129 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.45965916 |
130 | Pathways in cancer_Homo sapiens_hsa05200 | 0.45773070 |
131 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.45159828 |
132 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.44670988 |
133 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44328510 |
134 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42664006 |
135 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.41803363 |
136 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41705926 |
137 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.41347264 |
138 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.41105205 |
139 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.39883602 |
140 | Base excision repair_Homo sapiens_hsa03410 | 0.39586355 |
141 | DNA replication_Homo sapiens_hsa03030 | 0.39411532 |
142 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37331730 |
143 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.30729071 |