Rank | Gene Set | Z-score |
---|---|---|
1 | L-amino acid import (GO:0043092) | 5.74598389 |
2 | locomotory exploration behavior (GO:0035641) | 5.17365281 |
3 | amino acid import (GO:0043090) | 4.79402174 |
4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.75761112 |
5 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.72026206 |
6 | synaptic vesicle maturation (GO:0016188) | 4.71087075 |
7 | sodium ion export (GO:0071436) | 4.17241050 |
8 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.13721929 |
9 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.11251263 |
10 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.06403648 |
11 | vocalization behavior (GO:0071625) | 4.00744366 |
12 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.99230316 |
13 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.93939220 |
14 | cerebellar granule cell differentiation (GO:0021707) | 3.90115757 |
15 | layer formation in cerebral cortex (GO:0021819) | 3.88674127 |
16 | regulation of clathrin-mediated endocytosis (GO:2000369) | 3.84372776 |
17 | cellular potassium ion homeostasis (GO:0030007) | 3.83776443 |
18 | glutamate receptor signaling pathway (GO:0007215) | 3.77167293 |
19 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.76974260 |
20 | potassium ion homeostasis (GO:0055075) | 3.76017648 |
21 | positive regulation of synapse maturation (GO:0090129) | 3.74986242 |
22 | synaptic vesicle exocytosis (GO:0016079) | 3.74539738 |
23 | establishment of nucleus localization (GO:0040023) | 3.73524114 |
24 | glutamate secretion (GO:0014047) | 3.70240748 |
25 | neuronal ion channel clustering (GO:0045161) | 3.58568569 |
26 | neuronal action potential propagation (GO:0019227) | 3.53747740 |
27 | synaptic transmission, glutamatergic (GO:0035249) | 3.46990463 |
28 | postsynaptic membrane organization (GO:0001941) | 3.45952574 |
29 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.45356271 |
30 | desmosome organization (GO:0002934) | 3.41612990 |
31 | axon ensheathment in central nervous system (GO:0032291) | 3.41349834 |
32 | central nervous system myelination (GO:0022010) | 3.41349834 |
33 | exploration behavior (GO:0035640) | 3.41341215 |
34 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.40887150 |
35 | cell communication by electrical coupling (GO:0010644) | 3.40359633 |
36 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.38619886 |
37 | negative regulation of hormone metabolic process (GO:0032351) | 3.37166904 |
38 | negative regulation of hormone biosynthetic process (GO:0032353) | 3.37166904 |
39 | regulation of neurotransmitter transport (GO:0051588) | 3.36746326 |
40 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 3.35189376 |
41 | neurotransmitter secretion (GO:0007269) | 3.33005745 |
42 | neuron cell-cell adhesion (GO:0007158) | 3.32891350 |
43 | adult walking behavior (GO:0007628) | 3.32627837 |
44 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.32625852 |
45 | long-term memory (GO:0007616) | 3.30198838 |
46 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.29162815 |
47 | regulation of ARF protein signal transduction (GO:0032012) | 3.24968916 |
48 | regulation of synapse structural plasticity (GO:0051823) | 3.22866367 |
49 | transmission of nerve impulse (GO:0019226) | 3.22570461 |
50 | neuromuscular process controlling balance (GO:0050885) | 3.20977231 |
51 | presynaptic membrane organization (GO:0097090) | 3.20107911 |
52 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.19783561 |
53 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.18353893 |
54 | dendritic spine morphogenesis (GO:0060997) | 3.11550722 |
55 | neurotransmitter uptake (GO:0001504) | 3.09492217 |
56 | regulation of exocytosis (GO:0017157) | 3.05219048 |
57 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.05113191 |
58 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.04792241 |
59 | neuron-neuron synaptic transmission (GO:0007270) | 3.04176219 |
60 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.03022682 |
61 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.02715235 |
62 | gamma-aminobutyric acid transport (GO:0015812) | 3.00462960 |
63 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.98732267 |
64 | proline transport (GO:0015824) | 2.97753762 |
65 | cell differentiation in hindbrain (GO:0021533) | 2.96355654 |
66 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.95953184 |
67 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.94059398 |
68 | regulation of synaptic vesicle transport (GO:1902803) | 2.92372176 |
69 | regulation of synaptic transmission (GO:0050804) | 2.89501215 |
70 | presynaptic membrane assembly (GO:0097105) | 2.89235432 |
71 | retinal cone cell development (GO:0046549) | 2.88666769 |
72 | positive regulation of neurotransmitter transport (GO:0051590) | 2.88600292 |
73 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.87412877 |
74 | establishment of synaptic vesicle localization (GO:0097480) | 2.85448642 |
75 | synaptic vesicle transport (GO:0048489) | 2.85448642 |
76 | vesicle docking involved in exocytosis (GO:0006904) | 2.85401457 |
77 | synaptic vesicle endocytosis (GO:0048488) | 2.85377796 |
78 | acidic amino acid transport (GO:0015800) | 2.80676852 |
79 | positive regulation of fibroblast migration (GO:0010763) | 2.80363500 |
80 | regulation of postsynaptic membrane potential (GO:0060078) | 2.79845021 |
81 | regulation of synaptic plasticity (GO:0048167) | 2.79578345 |
82 | synaptic transmission (GO:0007268) | 2.79394784 |
83 | protein localization to synapse (GO:0035418) | 2.78776266 |
84 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.77713766 |
85 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.74270563 |
86 | positive regulation of membrane potential (GO:0045838) | 2.72083773 |
87 | positive regulation of vesicle fusion (GO:0031340) | 2.71291012 |
88 | regulation of synapse maturation (GO:0090128) | 2.69161999 |
89 | gonadal mesoderm development (GO:0007506) | 2.66841498 |
90 | signal complex assembly (GO:0007172) | 2.60119295 |
91 | activation of protein kinase A activity (GO:0034199) | 2.59948578 |
92 | keratinization (GO:0031424) | 2.54934447 |
93 | long-term synaptic potentiation (GO:0060291) | 2.53131449 |
94 | regulation of vesicle fusion (GO:0031338) | 2.52267617 |
95 | dendritic spine organization (GO:0097061) | 2.52015255 |
96 | auditory behavior (GO:0031223) | 2.51586280 |
97 | hemidesmosome assembly (GO:0031581) | 2.50597611 |
98 | long term synaptic depression (GO:0060292) | 2.49234398 |
99 | establishment of skin barrier (GO:0061436) | 2.49230775 |
100 | prepulse inhibition (GO:0060134) | 2.49041778 |
101 | dendrite morphogenesis (GO:0048813) | 2.48701991 |
102 | chemosensory behavior (GO:0007635) | 2.46963520 |
103 | response to histamine (GO:0034776) | 2.45980502 |
104 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.44970380 |
105 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.44221261 |
106 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.44098854 |
107 | neuromuscular process controlling posture (GO:0050884) | 2.42815463 |
108 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.40885220 |
109 | cellular sodium ion homeostasis (GO:0006883) | 2.40368588 |
110 | behavioral fear response (GO:0001662) | 2.40337250 |
111 | behavioral defense response (GO:0002209) | 2.40337250 |
112 | glycine transport (GO:0015816) | 2.39930347 |
113 | membrane depolarization (GO:0051899) | 2.39721029 |
114 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.39658119 |
115 | membrane depolarization during action potential (GO:0086010) | 2.39317323 |
116 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.39092467 |
117 | vesicle transport along microtubule (GO:0047496) | 2.38909529 |
118 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.38451539 |
119 | neurotransmitter transport (GO:0006836) | 2.37593945 |
120 | positive regulation of dendritic spine development (GO:0060999) | 2.37295104 |
121 | regulation of dendritic spine development (GO:0060998) | 2.37281462 |
122 | nucleus localization (GO:0051647) | 2.33340111 |
123 | neuromuscular process (GO:0050905) | 2.33124888 |
124 | potassium ion import (GO:0010107) | 2.31794880 |
125 | regulation of neurotransmitter levels (GO:0001505) | 2.30045603 |
126 | pre-miRNA processing (GO:0031054) | 2.29566953 |
127 | regulation of neurotransmitter secretion (GO:0046928) | 2.29173477 |
128 | intraspecies interaction between organisms (GO:0051703) | 2.28755998 |
129 | social behavior (GO:0035176) | 2.28755998 |
130 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.25150768 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.03359028 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.23361570 |
3 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.55173122 |
4 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.30316836 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.27090467 |
6 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.26366039 |
7 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.24823146 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.20446818 |
9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.20446818 |
10 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.18940867 |
11 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.06769145 |
12 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.98229947 |
13 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.97712289 |
14 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.89802444 |
15 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.86148116 |
16 | KDM2B_26808549_Chip-Seq_K562_Human | 1.85779278 |
17 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.85707972 |
18 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.85581894 |
19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.84881119 |
20 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.84766358 |
21 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.83224213 |
22 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.80598373 |
23 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.79649074 |
24 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.75551159 |
25 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.73366059 |
26 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.70752757 |
27 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.68432662 |
28 | TP53_16413492_ChIP-PET_HCT116_Human | 1.65394056 |
29 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.64163572 |
30 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.63773463 |
31 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.62932170 |
32 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.62311999 |
33 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.58101902 |
34 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.57650340 |
35 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.57179081 |
36 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.56217546 |
37 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.54524684 |
38 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.53631950 |
39 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.53476059 |
40 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.53111873 |
41 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.51705702 |
42 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.43792418 |
43 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.40812879 |
44 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.39432178 |
45 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.39055378 |
46 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.36579907 |
47 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34594678 |
48 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.34211948 |
49 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.33555626 |
50 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.31801012 |
51 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.30936390 |
52 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.30316629 |
53 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.29750740 |
54 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.27492853 |
55 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27258434 |
56 | RXR_22108803_ChIP-Seq_LS180_Human | 1.27247872 |
57 | * AR_19668381_ChIP-Seq_PC3_Human | 1.25670087 |
58 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.23889584 |
59 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.23665111 |
60 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.22927143 |
61 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.21567285 |
62 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.20619587 |
63 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.19708191 |
64 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.19630862 |
65 | * TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.19575462 |
66 | * POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.19575462 |
67 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.19030118 |
68 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.17632174 |
69 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.15782154 |
70 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.14833826 |
71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.14351664 |
72 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.13817571 |
73 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.13135346 |
74 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.13087323 |
75 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11932363 |
76 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.11632847 |
77 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.09952082 |
78 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.07906765 |
79 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.07232888 |
80 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.07216147 |
81 | * TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06460556 |
82 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.06224307 |
83 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.05019121 |
84 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.04746786 |
85 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04351076 |
86 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.03482384 |
87 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.03462352 |
88 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.03318312 |
89 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02769648 |
90 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.02497321 |
91 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.01685657 |
92 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.01544376 |
93 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.01098064 |
94 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.01087861 |
95 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00799068 |
96 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.00742623 |
97 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.98865243 |
98 | * FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.97808365 |
99 | * STAT3_23295773_ChIP-Seq_U87_Human | 0.97226658 |
100 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.96417045 |
101 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.96339951 |
102 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.94001370 |
103 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.93866696 |
104 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.93823348 |
105 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.93217405 |
106 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.92995331 |
107 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.92798594 |
108 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.92607909 |
109 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.92379613 |
110 | AR_25329375_ChIP-Seq_VCAP_Human | 0.92316065 |
111 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.90459353 |
112 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.90311251 |
113 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.89274707 |
114 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.88695490 |
115 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.88602493 |
116 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.88368092 |
117 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 0.88321251 |
118 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.87811509 |
119 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.86088178 |
120 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.85540945 |
121 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.84144181 |
122 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.83760639 |
123 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.83065904 |
124 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.83010976 |
125 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.82829211 |
126 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.82287589 |
127 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.81957006 |
128 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.81783135 |
129 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.81775119 |
130 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.81408037 |
131 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.80401278 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.11685826 |
2 | MP0003635_abnormal_synaptic_transmissio | 3.46965890 |
3 | MP0009046_muscle_twitch | 3.19061729 |
4 | MP0010234_abnormal_vibrissa_follicle | 2.94643387 |
5 | MP0000569_abnormal_digit_pigmentation | 2.76192247 |
6 | MP0002063_abnormal_learning/memory/cond | 2.61069134 |
7 | MP0003787_abnormal_imprinting | 2.55817244 |
8 | MP0003880_abnormal_central_pattern | 2.49564241 |
9 | MP0002796_impaired_skin_barrier | 2.47264662 |
10 | MP0009745_abnormal_behavioral_response | 2.44691437 |
11 | MP0008569_lethality_at_weaning | 2.37533989 |
12 | MP0002064_seizures | 2.28153728 |
13 | MP0003690_abnormal_glial_cell | 2.24270559 |
14 | MP0004270_analgesia | 2.23005211 |
15 | MP0002572_abnormal_emotion/affect_behav | 2.06876331 |
16 | MP0000579_abnormal_nail_morphology | 2.00084368 |
17 | MP0001984_abnormal_olfaction | 1.93171192 |
18 | MP0000383_abnormal_hair_follicle | 1.89204345 |
19 | MP0010678_abnormal_skin_adnexa | 1.79638165 |
20 | MP0001501_abnormal_sleep_pattern | 1.78954796 |
21 | MP0000920_abnormal_myelination | 1.72275537 |
22 | MP0001968_abnormal_touch/_nociception | 1.71736513 |
23 | MP0005423_abnormal_somatic_nervous | 1.71226468 |
24 | MP0002254_reproductive_system_inflammat | 1.64809224 |
25 | MP0003705_abnormal_hypodermis_morpholog | 1.61963259 |
26 | MP0002272_abnormal_nervous_system | 1.61885904 |
27 | MP0001486_abnormal_startle_reflex | 1.61736864 |
28 | MP0000604_amyloidosis | 1.55879947 |
29 | MP0002734_abnormal_mechanical_nocicepti | 1.53099992 |
30 | MP0001440_abnormal_grooming_behavior | 1.52030389 |
31 | MP0008961_abnormal_basal_metabolism | 1.48384907 |
32 | MP0002184_abnormal_innervation | 1.45671896 |
33 | MP0005076_abnormal_cell_differentiation | 1.44607764 |
34 | MP0003123_paternal_imprinting | 1.44253551 |
35 | MP0004885_abnormal_endolymph | 1.44144433 |
36 | MP0005646_abnormal_pituitary_gland | 1.41085584 |
37 | MP0004858_abnormal_nervous_system | 1.38010011 |
38 | MP0003879_abnormal_hair_cell | 1.36515261 |
39 | MP0001851_eye_inflammation | 1.33729374 |
40 | MP0008877_abnormal_DNA_methylation | 1.32958029 |
41 | MP0004811_abnormal_neuron_physiology | 1.32906876 |
42 | MP0003303_peritoneal_inflammation | 1.32773250 |
43 | MP0002877_abnormal_melanocyte_morpholog | 1.31384155 |
44 | MP0002067_abnormal_sensory_capabilities | 1.29269340 |
45 | MP0005499_abnormal_olfactory_system | 1.25547643 |
46 | MP0005394_taste/olfaction_phenotype | 1.25547643 |
47 | MP0005501_abnormal_skin_physiology | 1.24839882 |
48 | MP0002822_catalepsy | 1.23031968 |
49 | MP0001348_abnormal_lacrimal_gland | 1.22394323 |
50 | MP0002229_neurodegeneration | 1.21539091 |
51 | MP0002557_abnormal_social/conspecific_i | 1.19821624 |
52 | MP0009780_abnormal_chondrocyte_physiolo | 1.19593042 |
53 | MP0002735_abnormal_chemical_nociception | 1.17104918 |
54 | MP0005623_abnormal_meninges_morphology | 1.16194667 |
55 | MP0001849_ear_inflammation | 1.15535533 |
56 | MP0002736_abnormal_nociception_after | 1.14197457 |
57 | MP0001216_abnormal_epidermal_layer | 1.12971134 |
58 | MP0002733_abnormal_thermal_nociception | 1.12784554 |
59 | MP0003121_genomic_imprinting | 1.12382399 |
60 | MP0003634_abnormal_glial_cell | 1.12042258 |
61 | MP0010771_integument_phenotype | 1.11982846 |
62 | MP0001970_abnormal_pain_threshold | 1.11776229 |
63 | MP0003453_abnormal_keratinocyte_physiol | 1.06755256 |
64 | MP0004510_myositis | 1.05793205 |
65 | MP0008057_abnormal_DNA_replication | 1.05579317 |
66 | MP0001346_abnormal_lacrimal_gland | 1.04412604 |
67 | MP0003329_amyloid_beta_deposits | 1.04324513 |
68 | MP0003941_abnormal_skin_development | 1.00331748 |
69 | MP0000955_abnormal_spinal_cord | 0.99656779 |
70 | MP0005275_abnormal_skin_tensile | 0.98826895 |
71 | MP0001963_abnormal_hearing_physiology | 0.98661199 |
72 | MP0003045_fibrosis | 0.96869533 |
73 | MP0004924_abnormal_behavior | 0.96702765 |
74 | MP0005386_behavior/neurological_phenoty | 0.96702765 |
75 | MP0000778_abnormal_nervous_system | 0.94087300 |
76 | MP0002909_abnormal_adrenal_gland | 0.91763137 |
77 | MP0004142_abnormal_muscle_tone | 0.91112856 |
78 | MP0002638_abnormal_pupillary_reflex | 0.91057079 |
79 | MP0000467_abnormal_esophagus_morphology | 0.90482664 |
80 | MP0002152_abnormal_brain_morphology | 0.89541543 |
81 | MP0000647_abnormal_sebaceous_gland | 0.89478757 |
82 | MP0002882_abnormal_neuron_morphology | 0.88535268 |
83 | MP0004185_abnormal_adipocyte_glucose | 0.88385087 |
84 | MP0003632_abnormal_nervous_system | 0.88101730 |
85 | MP0000427_abnormal_hair_cycle | 0.87847942 |
86 | MP0002098_abnormal_vibrissa_morphology | 0.86866544 |
87 | MP0002066_abnormal_motor_capabilities/c | 0.86589288 |
88 | MP0004947_skin_inflammation | 0.84464708 |
89 | MP0001986_abnormal_taste_sensitivity | 0.84445139 |
90 | MP0003172_abnormal_lysosome_physiology | 0.83729357 |
91 | MP0009278_abnormal_bone_marrow | 0.80041203 |
92 | MP0003633_abnormal_nervous_system | 0.78889381 |
93 | MP0003300_gastrointestinal_ulcer | 0.77920794 |
94 | MP0003631_nervous_system_phenotype | 0.77806606 |
95 | MP0004145_abnormal_muscle_electrophysio | 0.77668526 |
96 | MP0003861_abnormal_nervous_system | 0.74823577 |
97 | MP0006082_CNS_inflammation | 0.74184885 |
98 | MP0005551_abnormal_eye_electrophysiolog | 0.72196439 |
99 | MP0008874_decreased_physiological_sensi | 0.71769727 |
100 | MP0002090_abnormal_vision | 0.71607881 |
101 | MP0006276_abnormal_autonomic_nervous | 0.71136092 |
102 | MP0005187_abnormal_penis_morphology | 0.70933150 |
103 | MP0003566_abnormal_cell_adhesion | 0.70348669 |
104 | MP0002060_abnormal_skin_morphology | 0.70165571 |
105 | MP0001177_atelectasis | 0.70094969 |
106 | MP0003075_altered_response_to | 0.70000725 |
107 | MP0008770_decreased_survivor_rate | 0.69665576 |
108 | MP0004043_abnormal_pH_regulation | 0.69184960 |
109 | MP0001299_abnormal_eye_distance/ | 0.69147891 |
110 | MP0000377_abnormal_hair_follicle | 0.68621926 |
111 | MP0001188_hyperpigmentation | 0.68091965 |
112 | MP0001485_abnormal_pinna_reflex | 0.67729202 |
113 | MP0006292_abnormal_olfactory_placode | 0.67509203 |
114 | MP0001502_abnormal_circadian_rhythm | 0.66031983 |
115 | MP0004742_abnormal_vestibular_system | 0.64408245 |
116 | MP0002069_abnormal_eating/drinking_beha | 0.63800138 |
117 | MP0005167_abnormal_blood-brain_barrier | 0.63080008 |
118 | MP0005535_abnormal_body_temperature | 0.62000524 |
119 | MP0010307_abnormal_tumor_latency | 0.59139783 |
120 | MP0003718_maternal_effect | 0.59111650 |
121 | MP0000015_abnormal_ear_pigmentation | 0.59095442 |
122 | MP0003385_abnormal_body_wall | 0.59086197 |
123 | MP0003122_maternal_imprinting | 0.59002653 |
124 | MP0003091_abnormal_cell_migration | 0.57211123 |
125 | MP0000566_synostosis | 0.56546737 |
126 | MP0002234_abnormal_pharynx_morphology | 0.56537553 |
127 | MP0005409_darkened_coat_color | 0.55600325 |
128 | MP0003755_abnormal_palate_morphology | 0.55402706 |
129 | MP0004484_altered_response_of | 0.54681811 |
130 | MP0005645_abnormal_hypothalamus_physiol | 0.54058583 |
131 | MP0002752_abnormal_somatic_nervous | 0.51990806 |
132 | MP0010769_abnormal_survival | 0.48635780 |
133 | MP0001905_abnormal_dopamine_level | 0.48601130 |
134 | MP0003890_abnormal_embryonic-extraembry | 0.46886920 |
135 | MP0002161_abnormal_fertility/fecundity | 0.46820305 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Neurofibrillary tangles (HP:0002185) | 4.63081383 |
2 | Focal motor seizures (HP:0011153) | 4.47029485 |
3 | Progressive cerebellar ataxia (HP:0002073) | 3.81851202 |
4 | Action tremor (HP:0002345) | 3.77828180 |
5 | Focal seizures (HP:0007359) | 3.70262213 |
6 | Myokymia (HP:0002411) | 3.66886855 |
7 | Cerebral inclusion bodies (HP:0100314) | 3.50890479 |
8 | Abnormality of the lower motor neuron (HP:0002366) | 3.49233496 |
9 | Genetic anticipation (HP:0003743) | 3.46078234 |
10 | Dysmetric saccades (HP:0000641) | 3.44603140 |
11 | Visual hallucinations (HP:0002367) | 3.38274808 |
12 | Neuronal loss in central nervous system (HP:0002529) | 3.31315421 |
13 | Spastic gait (HP:0002064) | 3.29527598 |
14 | Annular pancreas (HP:0001734) | 3.16765436 |
15 | Milia (HP:0001056) | 3.09010506 |
16 | Impaired smooth pursuit (HP:0007772) | 3.08718792 |
17 | Atonic seizures (HP:0010819) | 3.07269549 |
18 | Gaze-evoked nystagmus (HP:0000640) | 2.99799315 |
19 | Febrile seizures (HP:0002373) | 2.95333210 |
20 | Tetraplegia (HP:0002445) | 2.89217092 |
21 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.83164268 |
22 | Bradykinesia (HP:0002067) | 2.81036569 |
23 | Cerebral hypomyelination (HP:0006808) | 2.80645292 |
24 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.78087570 |
25 | Dysdiadochokinesis (HP:0002075) | 2.75915429 |
26 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.73168914 |
27 | Pointed chin (HP:0000307) | 2.56703852 |
28 | Peripheral hypomyelination (HP:0007182) | 2.54767437 |
29 | Hemiplegia (HP:0002301) | 2.52953802 |
30 | Lip pit (HP:0100267) | 2.50797749 |
31 | Epileptic encephalopathy (HP:0200134) | 2.49812266 |
32 | Limb dystonia (HP:0002451) | 2.49497451 |
33 | Torticollis (HP:0000473) | 2.48619660 |
34 | Diplopia (HP:0000651) | 2.46947016 |
35 | Abnormality of binocular vision (HP:0011514) | 2.46947016 |
36 | Broad-based gait (HP:0002136) | 2.45754814 |
37 | Status epilepticus (HP:0002133) | 2.45404688 |
38 | Obstructive sleep apnea (HP:0002870) | 2.44953531 |
39 | Spastic tetraparesis (HP:0001285) | 2.40315528 |
40 | Absence seizures (HP:0002121) | 2.37382940 |
41 | Papilledema (HP:0001085) | 2.36417662 |
42 | Ventricular fibrillation (HP:0001663) | 2.35846352 |
43 | Hypotrichosis (HP:0001006) | 2.33351486 |
44 | Abnormality of the corticospinal tract (HP:0002492) | 2.29855431 |
45 | Rigidity (HP:0002063) | 2.29420793 |
46 | Ankyloglossia (HP:0010296) | 2.28673759 |
47 | Epileptiform EEG discharges (HP:0011182) | 2.28293210 |
48 | Shallow orbits (HP:0000586) | 2.22644904 |
49 | Plantar hyperkeratosis (HP:0007556) | 2.21580077 |
50 | Intention tremor (HP:0002080) | 2.20125486 |
51 | Memory impairment (HP:0002354) | 2.17111303 |
52 | Urinary urgency (HP:0000012) | 2.17106856 |
53 | Sleep apnea (HP:0010535) | 2.14000516 |
54 | Truncal ataxia (HP:0002078) | 2.12682125 |
55 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.09982211 |
56 | Spinal canal stenosis (HP:0003416) | 2.09418707 |
57 | Increased IgE level (HP:0003212) | 2.08370802 |
58 | Focal dystonia (HP:0004373) | 2.07976923 |
59 | Dialeptic seizures (HP:0011146) | 2.06763600 |
60 | Dysmetria (HP:0001310) | 2.06129257 |
61 | Choreoathetosis (HP:0001266) | 2.06049368 |
62 | CNS hypomyelination (HP:0003429) | 2.05480994 |
63 | Oligodontia (HP:0000677) | 2.04137394 |
64 | Trigonocephaly (HP:0000243) | 2.03239002 |
65 | EEG with generalized epileptiform discharges (HP:0011198) | 2.02554288 |
66 | Pili torti (HP:0003777) | 2.01730241 |
67 | Palmoplantar hyperkeratosis (HP:0000972) | 2.01097249 |
68 | Inappropriate behavior (HP:0000719) | 2.00869400 |
69 | Anxiety (HP:0000739) | 1.99888726 |
70 | Generalized tonic-clonic seizures (HP:0002069) | 1.99467454 |
71 | Stereotypic behavior (HP:0000733) | 1.99445831 |
72 | Increased circulating renin level (HP:0000848) | 1.98404786 |
73 | Lower limb muscle weakness (HP:0007340) | 1.98224698 |
74 | Disinhibition (HP:0000734) | 1.98220930 |
75 | Gait ataxia (HP:0002066) | 1.97224214 |
76 | Thickened helices (HP:0000391) | 1.96701093 |
77 | Hyperventilation (HP:0002883) | 1.93631093 |
78 | Mutism (HP:0002300) | 1.92875456 |
79 | Hypsarrhythmia (HP:0002521) | 1.92465866 |
80 | Ocular albinism (HP:0001107) | 1.91075641 |
81 | Delusions (HP:0000746) | 1.90625634 |
82 | Impaired vibratory sensation (HP:0002495) | 1.90076845 |
83 | Apathy (HP:0000741) | 1.89365912 |
84 | Poor eye contact (HP:0000817) | 1.87879174 |
85 | Palmar hyperkeratosis (HP:0010765) | 1.87112575 |
86 | Postural tremor (HP:0002174) | 1.87098419 |
87 | Craniofacial dystonia (HP:0012179) | 1.86717604 |
88 | Rapidly progressive (HP:0003678) | 1.85768912 |
89 | Abnormality of oral frenula (HP:0000190) | 1.85024014 |
90 | Sparse scalp hair (HP:0002209) | 1.84705343 |
91 | Depression (HP:0000716) | 1.84218887 |
92 | Slow saccadic eye movements (HP:0000514) | 1.84008083 |
93 | Hyperacusis (HP:0010780) | 1.83509049 |
94 | Narrow palate (HP:0000189) | 1.81625602 |
95 | Abnormality of nail color (HP:0100643) | 1.81031319 |
96 | Abnormality of the periventricular white matter (HP:0002518) | 1.80447883 |
97 | Agnosia (HP:0010524) | 1.79532687 |
98 | Dementia (HP:0000726) | 1.79387148 |
99 | Absent frontal sinuses (HP:0002688) | 1.79345720 |
100 | Limb ataxia (HP:0002070) | 1.79065164 |
101 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.78737788 |
102 | Abnormality of the fingertips (HP:0001211) | 1.77125295 |
103 | Stomatitis (HP:0010280) | 1.76136073 |
104 | Impaired social interactions (HP:0000735) | 1.75684273 |
105 | Abnormal social behavior (HP:0012433) | 1.75684273 |
106 | Iris hypopigmentation (HP:0007730) | 1.74964762 |
107 | Clonus (HP:0002169) | 1.72197621 |
108 | Hemiparesis (HP:0001269) | 1.71597760 |
109 | Absent speech (HP:0001344) | 1.71593762 |
110 | Bundle branch block (HP:0011710) | 1.71375168 |
111 | Aqueductal stenosis (HP:0002410) | 1.71054383 |
112 | Scanning speech (HP:0002168) | 1.71041544 |
113 | Thick nail (HP:0001805) | 1.70610886 |
114 | Lower limb amyotrophy (HP:0007210) | 1.66495540 |
115 | Heterotopia (HP:0002282) | 1.66058774 |
116 | Cerebral aneurysm (HP:0004944) | 1.64934749 |
117 | Male infertility (HP:0003251) | 1.60599568 |
118 | Diminished motivation (HP:0000745) | 1.60077375 |
119 | Postural instability (HP:0002172) | 1.59779552 |
120 | Intellectual disability, profound (HP:0002187) | 1.59769253 |
121 | Insomnia (HP:0100785) | 1.59105555 |
122 | Abnormality of saccadic eye movements (HP:0000570) | 1.58451132 |
123 | Amyotrophic lateral sclerosis (HP:0007354) | 1.57418297 |
124 | Lower limb asymmetry (HP:0100559) | 1.56960363 |
125 | Aplasia of the phalanges of the hand (HP:0009802) | 1.56753434 |
126 | Aplasia involving bones of the extremities (HP:0009825) | 1.56753434 |
127 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.56753434 |
128 | Ankle clonus (HP:0011448) | 1.56187649 |
129 | Excessive salivation (HP:0003781) | 1.56032059 |
130 | Drooling (HP:0002307) | 1.56032059 |
131 | Supranuclear gaze palsy (HP:0000605) | 1.55077367 |
132 | Volvulus (HP:0002580) | 1.53754601 |
133 | Oligodactyly (hands) (HP:0001180) | 1.53718181 |
134 | Atrophic scars (HP:0001075) | 1.53378492 |
135 | Abnormal eating behavior (HP:0100738) | 1.53230341 |
136 | Fragile nails (HP:0001808) | 1.52634176 |
137 | Urethral obstruction (HP:0000796) | 1.52461487 |
138 | Macroorchidism (HP:0000053) | 1.50586569 |
139 | Abnormal blistering of the skin (HP:0008066) | 1.49624979 |
140 | Short 4th metacarpal (HP:0010044) | 1.48632623 |
141 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.48632623 |
142 | Neoplasm of the heart (HP:0100544) | 1.48511936 |
143 | Achilles tendon contracture (HP:0001771) | 1.48486146 |
144 | Papillary thyroid carcinoma (HP:0002895) | 1.48335753 |
145 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.48096807 |
146 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.44769854 |
147 | Obsessive-compulsive behavior (HP:0000722) | 1.44119225 |
148 | Upper limb amyotrophy (HP:0009129) | 1.43862283 |
149 | Distal upper limb amyotrophy (HP:0007149) | 1.43862283 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K9 | 4.05386111 |
2 | NTRK3 | 3.34519923 |
3 | EPHA4 | 2.89959835 |
4 | RIPK1 | 2.70808123 |
5 | EEF2K | 2.52645534 |
6 | KSR2 | 2.41050386 |
7 | MAP3K4 | 2.36466557 |
8 | TAOK1 | 2.26704356 |
9 | UHMK1 | 2.18401400 |
10 | LATS2 | 2.15591603 |
11 | TYRO3 | 2.12041956 |
12 | ARAF | 2.07085685 |
13 | PAK6 | 2.06204872 |
14 | STK38 | 2.02816706 |
15 | NEK6 | 2.00562971 |
16 | DAPK2 | 1.99292765 |
17 | CAMKK1 | 1.98625783 |
18 | PRKD3 | 1.94186461 |
19 | CDK12 | 1.89243169 |
20 | LATS1 | 1.89096189 |
21 | RIPK4 | 1.71756642 |
22 | MINK1 | 1.70699626 |
23 | CASK | 1.64302509 |
24 | MAP3K13 | 1.56361250 |
25 | CAMK1G | 1.49338376 |
26 | CAMKK2 | 1.47433099 |
27 | KSR1 | 1.47190552 |
28 | ALK | 1.46839786 |
29 | DMPK | 1.42926851 |
30 | MAP2K4 | 1.42743460 |
31 | SIK2 | 1.38357484 |
32 | MAP3K2 | 1.33301305 |
33 | STK11 | 1.30523318 |
34 | MAP3K6 | 1.26947343 |
35 | STK24 | 1.26530235 |
36 | FES | 1.17826597 |
37 | MARK2 | 1.13901649 |
38 | RAF1 | 1.11160363 |
39 | CAMK1D | 1.11061870 |
40 | RET | 1.09407834 |
41 | CDK5 | 1.04568089 |
42 | DAPK1 | 1.04218515 |
43 | WNK1 | 1.00870743 |
44 | PRKCH | 0.98901366 |
45 | DYRK1A | 0.97346236 |
46 | MOS | 0.96741005 |
47 | MAP2K7 | 0.96192530 |
48 | PINK1 | 0.95790513 |
49 | CDC7 | 0.94728884 |
50 | BRD4 | 0.94265529 |
51 | PRPF4B | 0.93151323 |
52 | MARK1 | 0.92007345 |
53 | SGK3 | 0.90558675 |
54 | PLK2 | 0.90506581 |
55 | CAMK1 | 0.90467025 |
56 | MAPKAPK3 | 0.90251468 |
57 | TRIB3 | 0.89532458 |
58 | BRAF | 0.89150755 |
59 | CAMK2B | 0.85260409 |
60 | BMX | 0.84317513 |
61 | MAP3K1 | 0.83898225 |
62 | CDK19 | 0.78124536 |
63 | * NTRK2 | 0.77154681 |
64 | MAPK12 | 0.75724685 |
65 | TNIK | 0.75014558 |
66 | SGK2 | 0.74335508 |
67 | PKN1 | 0.74135726 |
68 | PTK2B | 0.73957686 |
69 | CAMK4 | 0.72725610 |
70 | PTK6 | 0.71959135 |
71 | SGK1 | 0.71933882 |
72 | SCYL2 | 0.68335959 |
73 | GRK5 | 0.65700162 |
74 | MAPK10 | 0.64716303 |
75 | FER | 0.63418982 |
76 | MAP3K7 | 0.63329759 |
77 | NTRK1 | 0.61227261 |
78 | MAPK13 | 0.61212118 |
79 | CDK6 | 0.59354255 |
80 | PDK1 | 0.59228613 |
81 | CDK15 | 0.59199068 |
82 | PDGFRA | 0.58921047 |
83 | PRKD2 | 0.58723449 |
84 | CDK18 | 0.57179872 |
85 | STK3 | 0.56996279 |
86 | PTK2 | 0.55932175 |
87 | IRAK2 | 0.55480225 |
88 | RPS6KA3 | 0.53180067 |
89 | CDK11A | 0.52064980 |
90 | CDK9 | 0.51901090 |
91 | PDGFRB | 0.51731054 |
92 | PRKCG | 0.50760070 |
93 | STK39 | 0.50548791 |
94 | PRKCZ | 0.49707520 |
95 | PAK3 | 0.49493695 |
96 | FGFR1 | 0.48005888 |
97 | CDC42BPA | 0.47862562 |
98 | MAPKAPK5 | 0.47051145 |
99 | TAOK3 | 0.47005210 |
100 | JAK1 | 0.46378254 |
101 | NEK2 | 0.45349770 |
102 | BRSK1 | 0.44353565 |
103 | PNCK | 0.44325904 |
104 | TNK2 | 0.43888352 |
105 | CDK14 | 0.43588194 |
106 | PHKG1 | 0.43450454 |
107 | PHKG2 | 0.43450454 |
108 | CSNK1D | 0.42263323 |
109 | FGR | 0.42036149 |
110 | HCK | 0.41251127 |
111 | FYN | 0.41079549 |
112 | PDPK1 | 0.39653189 |
113 | FGFR2 | 0.39612223 |
114 | RPS6KB1 | 0.39466853 |
115 | CDK3 | 0.39072102 |
116 | CSNK1G2 | 0.38236287 |
117 | GSK3B | 0.37820056 |
118 | MAPK8 | 0.37783878 |
119 | JAK2 | 0.37675005 |
120 | CAMK2G | 0.37422859 |
121 | RPS6KB2 | 0.37162452 |
122 | SGK494 | 0.36641409 |
123 | SGK223 | 0.36641409 |
124 | FGFR3 | 0.36108968 |
125 | CAMK2A | 0.36040563 |
126 | STK10 | 0.35135661 |
127 | TRPM7 | 0.34971662 |
128 | ITK | 0.33916447 |
129 | ROCK2 | 0.30939568 |
130 | OXSR1 | 0.29974516 |
131 | PRKCQ | 0.23958602 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.55381555 |
2 | Long-term potentiation_Homo sapiens_hsa04720 | 2.37728266 |
3 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.10861753 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 1.99670743 |
5 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.89112431 |
6 | Olfactory transduction_Homo sapiens_hsa04740 | 1.88195389 |
7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.85838168 |
8 | Long-term depression_Homo sapiens_hsa04730 | 1.82562620 |
9 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.80741526 |
10 | Salivary secretion_Homo sapiens_hsa04970 | 1.70029068 |
11 | Morphine addiction_Homo sapiens_hsa05032 | 1.65200141 |
12 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.61774350 |
13 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.61106727 |
14 | GABAergic synapse_Homo sapiens_hsa04727 | 1.58280123 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.53296660 |
16 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.53023160 |
17 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.51127231 |
18 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.49731735 |
19 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.49242090 |
20 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.43155103 |
21 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.42958394 |
22 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.40991522 |
23 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.40983359 |
24 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.34590751 |
25 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.33963941 |
26 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.30671541 |
27 | Glioma_Homo sapiens_hsa05214 | 1.27008967 |
28 | Renin secretion_Homo sapiens_hsa04924 | 1.24679770 |
29 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.23108111 |
30 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.22849344 |
31 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.21491284 |
32 | * cAMP signaling pathway_Homo sapiens_hsa04024 | 1.16099235 |
33 | Insulin secretion_Homo sapiens_hsa04911 | 1.15665691 |
34 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.14564267 |
35 | Taste transduction_Homo sapiens_hsa04742 | 1.11607239 |
36 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.10420112 |
37 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.09754388 |
38 | Cocaine addiction_Homo sapiens_hsa05030 | 1.08491273 |
39 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.08045663 |
40 | Gap junction_Homo sapiens_hsa04540 | 1.07460714 |
41 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.05632434 |
42 | Melanogenesis_Homo sapiens_hsa04916 | 1.04631259 |
43 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.04001015 |
44 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.02581302 |
45 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.01557794 |
46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.00755523 |
47 | Axon guidance_Homo sapiens_hsa04360 | 0.99709790 |
48 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.97705773 |
49 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.96761543 |
50 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.96640183 |
51 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.96232917 |
52 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.95270072 |
53 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.90558193 |
54 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.89449725 |
55 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.88930594 |
56 | Endometrial cancer_Homo sapiens_hsa05213 | 0.88866052 |
57 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.88484570 |
58 | Colorectal cancer_Homo sapiens_hsa05210 | 0.85003214 |
59 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.82652924 |
60 | * Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.82433113 |
61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.82195668 |
62 | Platelet activation_Homo sapiens_hsa04611 | 0.81464415 |
63 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.77624154 |
64 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.76883458 |
65 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.76750003 |
66 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.75715078 |
67 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.75389215 |
68 | Phototransduction_Homo sapiens_hsa04744 | 0.73532401 |
69 | Adherens junction_Homo sapiens_hsa04520 | 0.72937673 |
70 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.72237769 |
71 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.71535726 |
72 | Endocytosis_Homo sapiens_hsa04144 | 0.71222690 |
73 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.71174359 |
74 | Circadian rhythm_Homo sapiens_hsa04710 | 0.70377702 |
75 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.70156883 |
76 | Prion diseases_Homo sapiens_hsa05020 | 0.69610497 |
77 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.69236804 |
78 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.68660890 |
79 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.68553305 |
80 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.68000301 |
81 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.67982437 |
82 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.67814376 |
83 | * Ras signaling pathway_Homo sapiens_hsa04014 | 0.67404124 |
84 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.66894437 |
85 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.65471547 |
86 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.64577086 |
87 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64470918 |
88 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63922606 |
89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.63081252 |
90 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.62933196 |
91 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.61644669 |
92 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.61040569 |
93 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.60999473 |
94 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.60401468 |
95 | * Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.60286621 |
96 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.58771392 |
97 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.57265531 |
98 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56938680 |
99 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.56634020 |
100 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.55220576 |
101 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.54421072 |
102 | Amoebiasis_Homo sapiens_hsa05146 | 0.53052392 |
103 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.52166733 |
104 | Focal adhesion_Homo sapiens_hsa04510 | 0.51974955 |
105 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.51762325 |
106 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.51671547 |
107 | Bile secretion_Homo sapiens_hsa04976 | 0.51524887 |
108 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51304036 |
109 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.48862251 |
110 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.44588776 |
111 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.43896795 |
112 | Tuberculosis_Homo sapiens_hsa05152 | 0.43236019 |
113 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.43086066 |
114 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.41445518 |
115 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.38324987 |
116 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.37344522 |
117 | Lysosome_Homo sapiens_hsa04142 | 0.37275721 |
118 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.37032024 |
119 | Phagosome_Homo sapiens_hsa04145 | 0.34144079 |
120 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.29481728 |