Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal large subunit biogenesis (GO:0042273) | 7.21897006 |
2 | viral transcription (GO:0019083) | 7.02154418 |
3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.81589053 |
4 | translational termination (GO:0006415) | 6.73162766 |
5 | ATP synthesis coupled proton transport (GO:0015986) | 6.47264353 |
6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.47264353 |
7 | ribosomal small subunit assembly (GO:0000028) | 6.32012911 |
8 | ribosomal small subunit biogenesis (GO:0042274) | 6.23084468 |
9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.00784576 |
10 | cotranslational protein targeting to membrane (GO:0006613) | 5.96048872 |
11 | protein targeting to ER (GO:0045047) | 5.92301185 |
12 | protein localization to endoplasmic reticulum (GO:0070972) | 5.90734961 |
13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.81116439 |
14 | translational elongation (GO:0006414) | 5.79958688 |
15 | heterochromatin organization (GO:0070828) | 5.70595998 |
16 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.60911551 |
17 | viral life cycle (GO:0019058) | 5.42095529 |
18 | proteasome assembly (GO:0043248) | 5.39795123 |
19 | cellular protein complex disassembly (GO:0043624) | 5.35507521 |
20 | respiratory electron transport chain (GO:0022904) | 5.31239183 |
21 | translational initiation (GO:0006413) | 5.30422441 |
22 | electron transport chain (GO:0022900) | 5.18455828 |
23 | maturation of 5.8S rRNA (GO:0000460) | 5.07395104 |
24 | maturation of SSU-rRNA (GO:0030490) | 5.05331592 |
25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.88917533 |
26 | DNA deamination (GO:0045006) | 4.81500313 |
27 | translation (GO:0006412) | 4.68055089 |
28 | protein complex disassembly (GO:0043241) | 4.62516460 |
29 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.52960731 |
30 | macromolecular complex disassembly (GO:0032984) | 4.40914282 |
31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.37947500 |
32 | protein neddylation (GO:0045116) | 4.36123309 |
33 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.26796267 |
34 | cellular component biogenesis (GO:0044085) | 4.25502917 |
35 | * protein targeting to mitochondrion (GO:0006626) | 4.20073237 |
36 | termination of RNA polymerase III transcription (GO:0006386) | 4.19378836 |
37 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.19378836 |
38 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.17027083 |
39 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.16406391 |
40 | negative regulation of ligase activity (GO:0051352) | 4.15940449 |
41 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.15940449 |
42 | * establishment of protein localization to mitochondrion (GO:0072655) | 4.13397009 |
43 | protein targeting to membrane (GO:0006612) | 4.13049735 |
44 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.11015138 |
45 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.97128899 |
46 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.95277924 |
47 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.95277924 |
48 | NADH dehydrogenase complex assembly (GO:0010257) | 3.95277924 |
49 | GTP biosynthetic process (GO:0006183) | 3.91896116 |
50 | protein complex biogenesis (GO:0070271) | 3.91418201 |
51 | peptidyl-histidine modification (GO:0018202) | 3.90588812 |
52 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.89103689 |
53 | intracellular protein transmembrane import (GO:0044743) | 3.88945429 |
54 | regulation of mitochondrial translation (GO:0070129) | 3.88428267 |
55 | * chaperone-mediated protein transport (GO:0072321) | 3.87666526 |
56 | spliceosomal snRNP assembly (GO:0000387) | 3.84025676 |
57 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.83386979 |
58 | * protein localization to mitochondrion (GO:0070585) | 3.81112600 |
59 | respiratory chain complex IV assembly (GO:0008535) | 3.74850126 |
60 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.72814386 |
61 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.72814386 |
62 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.70858201 |
63 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.70336752 |
64 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.70336752 |
65 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.70336752 |
66 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.69080874 |
67 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.67346310 |
68 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.64751681 |
69 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.64751681 |
70 | chromatin remodeling at centromere (GO:0031055) | 3.61536634 |
71 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.61403036 |
72 | cytochrome complex assembly (GO:0017004) | 3.59618307 |
73 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.57952715 |
74 | positive regulation of ligase activity (GO:0051351) | 3.57136641 |
75 | UTP biosynthetic process (GO:0006228) | 3.56056585 |
76 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.55386885 |
77 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.51390874 |
78 | rRNA processing (GO:0006364) | 3.50491298 |
79 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.48638395 |
80 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.48633450 |
81 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.48514430 |
82 | CENP-A containing nucleosome assembly (GO:0034080) | 3.48165895 |
83 | 7-methylguanosine mRNA capping (GO:0006370) | 3.41333574 |
84 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.41178079 |
85 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.40634386 |
86 | ribosome biogenesis (GO:0042254) | 3.40390078 |
87 | CTP metabolic process (GO:0046036) | 3.38161434 |
88 | CTP biosynthetic process (GO:0006241) | 3.38161434 |
89 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.37620603 |
90 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.37163720 |
91 | negative regulation of epidermal cell differentiation (GO:0045605) | 3.36928850 |
92 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.36867699 |
93 | protein import into peroxisome matrix (GO:0016558) | 3.35141141 |
94 | inner mitochondrial membrane organization (GO:0007007) | 3.35081328 |
95 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.34349387 |
96 | rRNA metabolic process (GO:0016072) | 3.33492930 |
97 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.31973103 |
98 | 7-methylguanosine RNA capping (GO:0009452) | 3.31485616 |
99 | RNA capping (GO:0036260) | 3.31485616 |
100 | L-serine metabolic process (GO:0006563) | 3.31324063 |
101 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.31235580 |
102 | base-excision repair, AP site formation (GO:0006285) | 3.29785258 |
103 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.29301778 |
104 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.29301778 |
105 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.28938112 |
106 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.27642882 |
107 | cullin deneddylation (GO:0010388) | 3.27264892 |
108 | DNA strand elongation (GO:0022616) | 3.26578122 |
109 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.25635452 |
110 | rRNA modification (GO:0000154) | 3.25515514 |
111 | regulation of cellular amine metabolic process (GO:0033238) | 3.24551132 |
112 | pseudouridine synthesis (GO:0001522) | 3.23180603 |
113 | ATP biosynthetic process (GO:0006754) | 3.21525892 |
114 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.21365329 |
115 | oxidative phosphorylation (GO:0006119) | 3.21035679 |
116 | establishment of integrated proviral latency (GO:0075713) | 3.20756433 |
117 | DNA damage response, detection of DNA damage (GO:0042769) | 3.18769443 |
118 | purine nucleobase biosynthetic process (GO:0009113) | 3.18456459 |
119 | DNA replication checkpoint (GO:0000076) | 3.18276645 |
120 | protein maturation by protein folding (GO:0022417) | 3.18255514 |
121 | regulation of ligase activity (GO:0051340) | 3.16118220 |
122 | formation of translation preinitiation complex (GO:0001731) | 3.15422565 |
123 | hydrogen ion transmembrane transport (GO:1902600) | 3.15259689 |
124 | spliceosomal complex assembly (GO:0000245) | 3.15197417 |
125 | mRNA catabolic process (GO:0006402) | 3.15022949 |
126 | UTP metabolic process (GO:0046051) | 3.13386992 |
127 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.13271609 |
Rank | Gene Set | Z-score |
---|---|---|
1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.52551572 |
2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.50912437 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.32274930 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.30903027 |
5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.19002792 |
6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.09422839 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.05513235 |
8 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.92377421 |
9 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.86099090 |
10 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.52788234 |
11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.32069955 |
12 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.26971587 |
13 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.06902044 |
14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.98395106 |
15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95031647 |
16 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.88257164 |
17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.87420118 |
18 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.81282065 |
19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.80902365 |
20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.79700939 |
21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.79002578 |
22 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.54618729 |
23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.44604072 |
24 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.37447232 |
25 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.26800920 |
26 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.20043085 |
27 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.18034115 |
28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.11039903 |
29 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.03735012 |
30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.01623859 |
31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.98954067 |
32 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.95685643 |
33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.94521047 |
34 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.92684992 |
35 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.91822639 |
36 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.61910024 |
37 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.61180275 |
38 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.60549192 |
39 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.60380722 |
40 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.53274904 |
41 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.49828959 |
42 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.48401929 |
43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.47554607 |
44 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.44519329 |
45 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.41492616 |
46 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39111530 |
47 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.39013749 |
48 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.35666271 |
49 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.35236761 |
50 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.33406619 |
51 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.33111732 |
52 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32147618 |
53 | * YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.30674537 |
54 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.30592686 |
55 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.29740659 |
56 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.29379970 |
57 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.29126188 |
58 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.28972391 |
59 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.28780095 |
60 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.26222093 |
61 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25392394 |
62 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.22717924 |
63 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.19490192 |
64 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.15002758 |
65 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.09708957 |
66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.07548205 |
67 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.06684006 |
68 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.06207137 |
69 | * EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.04975008 |
70 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.04564752 |
71 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.04501294 |
72 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.03244709 |
73 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.02721496 |
74 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.02039728 |
75 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.01806681 |
76 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.01742255 |
77 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.00190257 |
78 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.99979540 |
79 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.99973367 |
80 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.97432928 |
81 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.97284630 |
82 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.96618941 |
83 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.94164101 |
84 | * SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.93448466 |
85 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.91926153 |
86 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.91828277 |
87 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.91524525 |
88 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.91493639 |
89 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.90251214 |
90 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.87678018 |
91 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.87394661 |
92 | * TFEB_21752829_ChIP-Seq_HELA_Human | 0.87023870 |
93 | * RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.86882335 |
94 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.85381483 |
95 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.84762907 |
96 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.83479795 |
97 | * STAT1_20625510_ChIP-Seq_HELA_Human | 0.80931461 |
98 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.80518208 |
99 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.80335042 |
100 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.79900163 |
101 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.79405095 |
102 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.79402182 |
103 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.79136348 |
104 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.79134042 |
105 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.76737293 |
106 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.75831962 |
107 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.75075514 |
108 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.74942723 |
109 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.74486917 |
110 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.73407898 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 5.24118236 |
2 | MP0003693_abnormal_embryo_hatching | 4.32139923 |
3 | MP0003806_abnormal_nucleotide_metabolis | 3.89580121 |
4 | MP0008932_abnormal_embryonic_tissue | 3.20733694 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.10184830 |
6 | MP0003718_maternal_effect | 2.79788159 |
7 | MP0003186_abnormal_redox_activity | 2.56067142 |
8 | MP0001529_abnormal_vocalization | 2.55446844 |
9 | MP0003315_abnormal_perineum_morphology | 2.42337779 |
10 | MP0003011_delayed_dark_adaptation | 2.36367199 |
11 | MP0006036_abnormal_mitochondrial_physio | 2.32286621 |
12 | MP0003111_abnormal_nucleus_morphology | 2.22180270 |
13 | MP0003077_abnormal_cell_cycle | 2.17511069 |
14 | MP0003136_yellow_coat_color | 2.10605586 |
15 | MP0005409_darkened_coat_color | 2.09365204 |
16 | MP0010030_abnormal_orbit_morphology | 2.00801440 |
17 | MP0001905_abnormal_dopamine_level | 1.97668849 |
18 | MP0001727_abnormal_embryo_implantation | 1.93085486 |
19 | MP0001730_embryonic_growth_arrest | 1.78660237 |
20 | MP0001293_anophthalmia | 1.76593011 |
21 | MP0000750_abnormal_muscle_regeneration | 1.62200187 |
22 | MP0006276_abnormal_autonomic_nervous | 1.55145442 |
23 | MP0005451_abnormal_body_composition | 1.53819801 |
24 | MP0006035_abnormal_mitochondrial_morpho | 1.51102002 |
25 | MP0001919_abnormal_reproductive_system | 1.44736692 |
26 | MP0002751_abnormal_autonomic_nervous | 1.44721048 |
27 | MP0002638_abnormal_pupillary_reflex | 1.44669204 |
28 | MP0008260_abnormal_autophagy | 1.44408144 |
29 | MP0001986_abnormal_taste_sensitivity | 1.43820240 |
30 | MP0002736_abnormal_nociception_after | 1.43656762 |
31 | MP0004381_abnormal_hair_follicle | 1.38988487 |
32 | MP0002653_abnormal_ependyma_morphology | 1.38790665 |
33 | MP0010094_abnormal_chromosome_stability | 1.37342447 |
34 | MP0004142_abnormal_muscle_tone | 1.36357600 |
35 | MP0003646_muscle_fatigue | 1.35981140 |
36 | MP0004133_heterotaxia | 1.35530460 |
37 | MP0009840_abnormal_foam_cell | 1.34619463 |
38 | MP0005499_abnormal_olfactory_system | 1.33801803 |
39 | MP0005394_taste/olfaction_phenotype | 1.33801803 |
40 | MP0003941_abnormal_skin_development | 1.32613201 |
41 | MP0002132_abnormal_respiratory_system | 1.30530740 |
42 | MP0003786_premature_aging | 1.29926716 |
43 | MP0000049_abnormal_middle_ear | 1.28911989 |
44 | MP0002102_abnormal_ear_morphology | 1.23942210 |
45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22934923 |
46 | MP0003938_abnormal_ear_development | 1.22856470 |
47 | MP0006292_abnormal_olfactory_placode | 1.19857961 |
48 | MP0005670_abnormal_white_adipose | 1.19831708 |
49 | MP0001764_abnormal_homeostasis | 1.19189822 |
50 | MP0003123_paternal_imprinting | 1.19137161 |
51 | MP0002733_abnormal_thermal_nociception | 1.17828713 |
52 | MP0005332_abnormal_amino_acid | 1.17768147 |
53 | MP0009697_abnormal_copulation | 1.17383097 |
54 | MP0008877_abnormal_DNA_methylation | 1.15908350 |
55 | MP0008058_abnormal_DNA_repair | 1.15174483 |
56 | MP0005408_hypopigmentation | 1.14761233 |
57 | MP0003880_abnormal_central_pattern | 1.14263756 |
58 | MP0005389_reproductive_system_phenotype | 1.14159651 |
59 | MP0002234_abnormal_pharynx_morphology | 1.11702728 |
60 | MP0008995_early_reproductive_senescence | 1.11124925 |
61 | MP0000762_abnormal_tongue_morphology | 1.10371937 |
62 | MP0001188_hyperpigmentation | 1.09377845 |
63 | MP0001853_heart_inflammation | 1.07971330 |
64 | MP0002210_abnormal_sex_determination | 1.07557314 |
65 | MP0001970_abnormal_pain_threshold | 1.06555656 |
66 | MP0002163_abnormal_gland_morphology | 1.04164182 |
67 | MP0006072_abnormal_retinal_apoptosis | 1.03758178 |
68 | MP0000678_abnormal_parathyroid_gland | 1.02990146 |
69 | MP0005636_abnormal_mineral_homeostasis | 1.01814894 |
70 | MP0001968_abnormal_touch/_nociception | 1.01210984 |
71 | MP0003656_abnormal_erythrocyte_physiolo | 1.01196587 |
72 | MP0002139_abnormal_hepatobiliary_system | 0.98373879 |
73 | MP0005379_endocrine/exocrine_gland_phen | 0.97134025 |
74 | MP0001697_abnormal_embryo_size | 0.97004150 |
75 | MP0002938_white_spotting | 0.96547082 |
76 | MP0008057_abnormal_DNA_replication | 0.95506752 |
77 | MP0005083_abnormal_biliary_tract | 0.95414564 |
78 | MP0002160_abnormal_reproductive_system | 0.94705792 |
79 | MP0004019_abnormal_vitamin_homeostasis | 0.94314677 |
80 | MP0005084_abnormal_gallbladder_morpholo | 0.92067742 |
81 | MP0004145_abnormal_muscle_electrophysio | 0.91314965 |
82 | MP0002085_abnormal_embryonic_tissue | 0.90673613 |
83 | MP0001145_abnormal_male_reproductive | 0.90012006 |
84 | MP0000358_abnormal_cell_content/ | 0.89917265 |
85 | MP0004147_increased_porphyrin_level | 0.89046669 |
86 | MP0003937_abnormal_limbs/digits/tail_de | 0.88563808 |
87 | MP0005085_abnormal_gallbladder_physiolo | 0.87496761 |
88 | MP0005266_abnormal_metabolism | 0.86730147 |
89 | MP0008789_abnormal_olfactory_epithelium | 0.86284188 |
90 | MP0002876_abnormal_thyroid_physiology | 0.85100260 |
91 | MP0001542_abnormal_bone_strength | 0.85069553 |
92 | MP0001485_abnormal_pinna_reflex | 0.84665037 |
93 | MP0009333_abnormal_splenocyte_physiolog | 0.83782233 |
94 | MP0000653_abnormal_sex_gland | 0.82550255 |
95 | MP0002837_dystrophic_cardiac_calcinosis | 0.81556037 |
96 | MP0002697_abnormal_eye_size | 0.81036702 |
97 | MP0000372_irregular_coat_pigmentation | 0.80283872 |
98 | MP0005360_urolithiasis | 0.79313311 |
99 | MP0000631_abnormal_neuroendocrine_gland | 0.79186804 |
100 | MP0002735_abnormal_chemical_nociception | 0.79113683 |
101 | MP0009053_abnormal_anal_canal | 0.78607468 |
102 | MP0005380_embryogenesis_phenotype | 0.77538786 |
103 | MP0001672_abnormal_embryogenesis/_devel | 0.77538786 |
104 | MP0002111_abnormal_tail_morphology | 0.76874881 |
105 | MP0001929_abnormal_gametogenesis | 0.76641826 |
106 | MP0000749_muscle_degeneration | 0.76600647 |
107 | MP0003119_abnormal_digestive_system | 0.75704186 |
108 | MP0003121_genomic_imprinting | 0.75137198 |
109 | MP0002249_abnormal_larynx_morphology | 0.74627537 |
110 | MP0002233_abnormal_nose_morphology | 0.74422237 |
111 | MP0000313_abnormal_cell_death | 0.72480075 |
112 | MP0009672_abnormal_birth_weight | 0.72407952 |
113 | MP0002734_abnormal_mechanical_nocicepti | 0.72110746 |
114 | MP0005646_abnormal_pituitary_gland | 0.71565952 |
115 | MP0000490_abnormal_crypts_of | 0.71253590 |
116 | MP0005501_abnormal_skin_physiology | 0.70628025 |
117 | MP0002095_abnormal_skin_pigmentation | 0.69664342 |
118 | MP0005376_homeostasis/metabolism_phenot | 0.69370906 |
119 | MP0002277_abnormal_respiratory_mucosa | 0.68934427 |
120 | MP0002272_abnormal_nervous_system | 0.68642875 |
121 | MP0002084_abnormal_developmental_patter | 0.66814413 |
122 | MP0001881_abnormal_mammary_gland | 0.65140975 |
123 | MP0008875_abnormal_xenobiotic_pharmacok | 0.63983513 |
124 | MP0000858_altered_metastatic_potential | 0.63971926 |
125 | MP0003195_calcinosis | 0.63219268 |
126 | MP0002752_abnormal_somatic_nervous | 0.63094677 |
127 | MP0003221_abnormal_cardiomyocyte_apopto | 0.63001865 |
128 | MP0005330_cardiomyopathy | 0.62975869 |
129 | MP0005381_digestive/alimentary_phenotyp | 0.62965282 |
130 | MP0002822_catalepsy | 0.62888131 |
131 | MP0001286_abnormal_eye_development | 0.62386699 |
132 | MP0001756_abnormal_urination | 0.62217369 |
133 | MP0000350_abnormal_cell_proliferation | 0.61624194 |
134 | MP0008872_abnormal_physiological_respon | 0.61392780 |
135 | MP0003638_abnormal_response/metabolism_ | 0.61258746 |
136 | MP0009250_abnormal_appendicular_skeleto | 0.60966368 |
137 | MP0002080_prenatal_lethality | 0.60905523 |
138 | MP0001663_abnormal_digestive_system | 0.60190243 |
139 | MP0002332_abnormal_exercise_endurance | 0.59995409 |
140 | MP0000920_abnormal_myelination | 0.59770157 |
141 | MP0005075_abnormal_melanosome_morpholog | 0.59640362 |
142 | MP0008007_abnormal_cellular_replicative | 0.59483308 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 6.19934865 |
2 | Mitochondrial inheritance (HP:0001427) | 5.69992607 |
3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.54304924 |
4 | Acute encephalopathy (HP:0006846) | 5.30742123 |
5 | Hepatocellular necrosis (HP:0001404) | 5.25567359 |
6 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 5.24123493 |
7 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 5.24123493 |
8 | Increased CSF lactate (HP:0002490) | 5.08905912 |
9 | Progressive macrocephaly (HP:0004481) | 4.89537756 |
10 | Hepatic necrosis (HP:0002605) | 4.78910620 |
11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.65414075 |
12 | Increased hepatocellular lipid droplets (HP:0006565) | 4.51310665 |
13 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.42077274 |
14 | Reticulocytopenia (HP:0001896) | 4.20368984 |
15 | Abnormal number of erythroid precursors (HP:0012131) | 4.14332636 |
16 | Lipid accumulation in hepatocytes (HP:0006561) | 4.11127531 |
17 | Macrocytic anemia (HP:0001972) | 4.01438291 |
18 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.98003137 |
19 | Cerebral edema (HP:0002181) | 3.93120009 |
20 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.90239178 |
21 | Renal Fanconi syndrome (HP:0001994) | 3.77916905 |
22 | Increased serum lactate (HP:0002151) | 3.67260727 |
23 | Respiratory failure (HP:0002878) | 3.67087920 |
24 | 3-Methylglutaconic aciduria (HP:0003535) | 3.61183687 |
25 | Increased intramyocellular lipid droplets (HP:0012240) | 3.51492687 |
26 | Brushfield spots (HP:0001088) | 3.38751291 |
27 | Exercise intolerance (HP:0003546) | 3.35554458 |
28 | Lactic acidosis (HP:0003128) | 3.31172875 |
29 | Optic disc pallor (HP:0000543) | 3.30316086 |
30 | Cerebral hypomyelination (HP:0006808) | 3.25100802 |
31 | Leukodystrophy (HP:0002415) | 3.12029130 |
32 | Pallor (HP:0000980) | 3.06407603 |
33 | Increased muscle lipid content (HP:0009058) | 3.05221122 |
34 | Abnormality of glycolysis (HP:0004366) | 3.05116928 |
35 | Increased serum pyruvate (HP:0003542) | 3.05116928 |
36 | Exertional dyspnea (HP:0002875) | 3.03122903 |
37 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.86888311 |
38 | CNS demyelination (HP:0007305) | 2.84341938 |
39 | Secondary amenorrhea (HP:0000869) | 2.80665488 |
40 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.69991862 |
41 | Hyperphosphaturia (HP:0003109) | 2.68196980 |
42 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.66387733 |
43 | Premature ovarian failure (HP:0008209) | 2.63142139 |
44 | Respiratory difficulties (HP:0002880) | 2.62116158 |
45 | Amniotic constriction ring (HP:0009775) | 2.59972304 |
46 | Abnormality of placental membranes (HP:0011409) | 2.59972304 |
47 | Lethargy (HP:0001254) | 2.49034439 |
48 | Progressive external ophthalmoplegia (HP:0000590) | 2.48444204 |
49 | Emotional lability (HP:0000712) | 2.44497308 |
50 | Abnormality of renal resorption (HP:0011038) | 2.43207937 |
51 | Reduced antithrombin III activity (HP:0001976) | 2.40159901 |
52 | Methylmalonic aciduria (HP:0012120) | 2.40018110 |
53 | Gonadotropin excess (HP:0000837) | 2.38537337 |
54 | Oral leukoplakia (HP:0002745) | 2.35910803 |
55 | Aplastic anemia (HP:0001915) | 2.32123940 |
56 | Colon cancer (HP:0003003) | 2.30523142 |
57 | Rough bone trabeculation (HP:0100670) | 2.30162748 |
58 | Parakeratosis (HP:0001036) | 2.29947014 |
59 | Poor suck (HP:0002033) | 2.29756948 |
60 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.28699866 |
61 | Abnormality of alanine metabolism (HP:0010916) | 2.28699866 |
62 | Hyperalaninemia (HP:0003348) | 2.28699866 |
63 | Adenoma sebaceum (HP:0009720) | 2.27986381 |
64 | Angiofibromas (HP:0010615) | 2.27986381 |
65 | Abnormal protein glycosylation (HP:0012346) | 2.27731933 |
66 | Abnormal glycosylation (HP:0012345) | 2.27731933 |
67 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.27731933 |
68 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.27731933 |
69 | Concave nail (HP:0001598) | 2.24404364 |
70 | Breast hypoplasia (HP:0003187) | 2.24179683 |
71 | Abnormality of urine glucose concentration (HP:0011016) | 2.23590382 |
72 | Glycosuria (HP:0003076) | 2.23590382 |
73 | Generalized aminoaciduria (HP:0002909) | 2.23300663 |
74 | Degeneration of anterior horn cells (HP:0002398) | 2.22750162 |
75 | Abnormality of the anterior horn cell (HP:0006802) | 2.22750162 |
76 | Absent thumb (HP:0009777) | 2.22641561 |
77 | Abnormal urine phosphate concentration (HP:0012599) | 2.20987974 |
78 | Abnormal hemoglobin (HP:0011902) | 2.19116431 |
79 | Microretrognathia (HP:0000308) | 2.14217625 |
80 | Microvesicular hepatic steatosis (HP:0001414) | 2.12147214 |
81 | Abnormality of serum amino acid levels (HP:0003112) | 2.11590655 |
82 | Cleft eyelid (HP:0000625) | 2.11031493 |
83 | Methylmalonic acidemia (HP:0002912) | 2.05804564 |
84 | Death in infancy (HP:0001522) | 2.05618397 |
85 | Seborrheic dermatitis (HP:0001051) | 2.02953613 |
86 | Poor head control (HP:0002421) | 2.02695859 |
87 | X-linked dominant inheritance (HP:0001423) | 2.00549907 |
88 | Female pseudohermaphroditism (HP:0010458) | 2.00417705 |
89 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.00216991 |
90 | Birth length less than 3rd percentile (HP:0003561) | 1.95269173 |
91 | Epiphyseal stippling (HP:0010655) | 1.91041674 |
92 | Hyperglycinemia (HP:0002154) | 1.91002090 |
93 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88638783 |
94 | Testicular atrophy (HP:0000029) | 1.87514840 |
95 | Sparse eyelashes (HP:0000653) | 1.86000392 |
96 | Delusions (HP:0000746) | 1.85800243 |
97 | Meckel diverticulum (HP:0002245) | 1.85668739 |
98 | Myokymia (HP:0002411) | 1.82654291 |
99 | Abnormal number of incisors (HP:0011064) | 1.81006927 |
100 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.80846142 |
101 | Muscle fiber atrophy (HP:0100295) | 1.79822777 |
102 | Ragged-red muscle fibers (HP:0003200) | 1.79797467 |
103 | Trismus (HP:0000211) | 1.79622659 |
104 | Cerebellar dysplasia (HP:0007033) | 1.78565944 |
105 | Ependymoma (HP:0002888) | 1.78534461 |
106 | Abnormality of the axillary hair (HP:0100134) | 1.78427928 |
107 | Abnormality of secondary sexual hair (HP:0009888) | 1.78427928 |
108 | Facial cleft (HP:0002006) | 1.77945361 |
109 | Progressive muscle weakness (HP:0003323) | 1.76018095 |
110 | Abnormality of the ileum (HP:0001549) | 1.75183740 |
111 | Abnormal trabecular bone morphology (HP:0100671) | 1.74871217 |
112 | Triphalangeal thumb (HP:0001199) | 1.74499007 |
113 | Type I transferrin isoform profile (HP:0003642) | 1.74454364 |
114 | Atelectasis (HP:0100750) | 1.72746180 |
115 | Abnormality of the preputium (HP:0100587) | 1.70167415 |
116 | Megaloblastic anemia (HP:0001889) | 1.68503526 |
117 | Blindness (HP:0000618) | 1.68288535 |
118 | Abnormality of methionine metabolism (HP:0010901) | 1.68006481 |
119 | Horseshoe kidney (HP:0000085) | 1.67843730 |
120 | Septo-optic dysplasia (HP:0100842) | 1.67538492 |
121 | Neuroendocrine neoplasm (HP:0100634) | 1.67034897 |
122 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.65395638 |
123 | Patellar aplasia (HP:0006443) | 1.65392174 |
124 | Opisthotonus (HP:0002179) | 1.64523749 |
125 | Pancytopenia (HP:0001876) | 1.64489510 |
126 | Abnormality of the labia minora (HP:0012880) | 1.63960936 |
127 | Type 2 muscle fiber atrophy (HP:0003554) | 1.63885535 |
128 | Multiple enchondromatosis (HP:0005701) | 1.63764438 |
129 | Hypertensive crisis (HP:0100735) | 1.63067915 |
130 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.62528694 |
131 | Dicarboxylic aciduria (HP:0003215) | 1.62528694 |
132 | Partial duplication of the phalanx of hand (HP:0009999) | 1.62283852 |
133 | Gliosis (HP:0002171) | 1.61918675 |
134 | Partial duplication of thumb phalanx (HP:0009944) | 1.61552397 |
135 | Vomiting (HP:0002013) | 1.59905723 |
136 | External ophthalmoplegia (HP:0000544) | 1.59410546 |
137 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.57672191 |
138 | Depressed nasal ridge (HP:0000457) | 1.57570335 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EIF2AK1 | 6.14955888 |
2 | VRK2 | 5.98503637 |
3 | PBK | 4.46017049 |
4 | EIF2AK3 | 3.95590541 |
5 | NME2 | 3.88171084 |
6 | MAP3K11 | 3.50299267 |
7 | BUB1 | 3.39516616 |
8 | STK16 | 3.17921581 |
9 | TLK1 | 2.98764590 |
10 | WEE1 | 2.84766415 |
11 | ACVR1B | 2.57988074 |
12 | TESK2 | 2.52721846 |
13 | NME1 | 2.24629445 |
14 | BRSK1 | 2.02694945 |
15 | NEK1 | 1.88919392 |
16 | BMPR1B | 1.87680263 |
17 | PDK2 | 1.77983140 |
18 | NUAK1 | 1.70177347 |
19 | TAF1 | 1.67519614 |
20 | ARAF | 1.65923658 |
21 | PIM2 | 1.61900457 |
22 | CASK | 1.58646519 |
23 | SRPK1 | 1.54848281 |
24 | BCKDK | 1.53630989 |
25 | RPS6KA4 | 1.51382372 |
26 | LIMK1 | 1.49086465 |
27 | VRK1 | 1.48193974 |
28 | AURKA | 1.34416825 |
29 | EIF2AK2 | 1.19014459 |
30 | BRAF | 1.13535187 |
31 | TESK1 | 1.13461082 |
32 | MKNK2 | 1.12247361 |
33 | PNCK | 1.11099174 |
34 | CHEK2 | 1.08436551 |
35 | DYRK3 | 1.05238715 |
36 | ABL2 | 1.03121909 |
37 | CDK19 | 0.99749610 |
38 | TGFBR1 | 0.98255826 |
39 | IRAK3 | 0.98236144 |
40 | KDR | 0.96795912 |
41 | MKNK1 | 0.95952229 |
42 | PLK4 | 0.94957522 |
43 | DYRK2 | 0.91475270 |
44 | PAK4 | 0.89941153 |
45 | TSSK6 | 0.88014262 |
46 | DAPK1 | 0.86557745 |
47 | ADRBK1 | 0.85699285 |
48 | RPS6KA5 | 0.84501446 |
49 | STK39 | 0.82748016 |
50 | CSNK1G1 | 0.82621069 |
51 | EPHB1 | 0.82115364 |
52 | IRAK2 | 0.81496732 |
53 | SMG1 | 0.76161933 |
54 | MYLK | 0.74204449 |
55 | CSNK1G2 | 0.72159716 |
56 | PAK1 | 0.71230256 |
57 | DAPK3 | 0.70051538 |
58 | ILK | 0.69617720 |
59 | PLK1 | 0.69203692 |
60 | OXSR1 | 0.68940049 |
61 | MAP4K2 | 0.68131865 |
62 | IRAK4 | 0.68069623 |
63 | PASK | 0.65034170 |
64 | TRIM28 | 0.64797058 |
65 | MAP2K2 | 0.64012223 |
66 | CHEK1 | 0.61492742 |
67 | MAP2K7 | 0.60569259 |
68 | IRAK1 | 0.59219612 |
69 | CSNK2A1 | 0.59058232 |
70 | GRK5 | 0.59048763 |
71 | BCR | 0.58372520 |
72 | WNK3 | 0.57896038 |
73 | CSNK1A1L | 0.57662670 |
74 | EPHA2 | 0.57456019 |
75 | CCNB1 | 0.55087285 |
76 | CDK7 | 0.53764429 |
77 | AURKB | 0.52207487 |
78 | OBSCN | 0.51946292 |
79 | CSNK2A2 | 0.51218741 |
80 | NEK2 | 0.50106560 |
81 | MST4 | 0.49747995 |
82 | GRK1 | 0.48723804 |
83 | WNK4 | 0.46480691 |
84 | UHMK1 | 0.46364895 |
85 | MAP3K12 | 0.44510199 |
86 | ZAK | 0.43105883 |
87 | ATM | 0.41869129 |
88 | MAP3K8 | 0.41408083 |
89 | CAMK2B | 0.41309528 |
90 | ERBB2 | 0.41198451 |
91 | PRKCI | 0.40810613 |
92 | RPS6KA2 | 0.40714936 |
93 | STK38L | 0.40587806 |
94 | CSNK1E | 0.40374641 |
95 | ADRBK2 | 0.40366778 |
96 | RPS6KB2 | 0.40262058 |
97 | TIE1 | 0.39973966 |
98 | SCYL2 | 0.39970668 |
99 | TAOK2 | 0.39784932 |
100 | PHKG1 | 0.38467254 |
101 | PHKG2 | 0.38467254 |
102 | LRRK2 | 0.37605538 |
103 | RPS6KC1 | 0.37360929 |
104 | RPS6KL1 | 0.37360929 |
105 | PTK2B | 0.37240356 |
106 | INSRR | 0.36060077 |
107 | BRSK2 | 0.35434363 |
108 | AKT2 | 0.35363796 |
109 | CDK2 | 0.35081634 |
110 | CSNK1A1 | 0.34437289 |
111 | TTK | 0.34391473 |
112 | MAPKAPK3 | 0.34387443 |
113 | CSNK1G3 | 0.34381275 |
114 | PIK3CG | 0.33883441 |
115 | CDK4 | 0.33178317 |
116 | CDK11A | 0.32041701 |
117 | EPHB2 | 0.31919746 |
118 | CAMK2G | 0.31673437 |
119 | BLK | 0.31081302 |
120 | RPS6KA6 | 0.29734647 |
121 | MARK1 | 0.28817368 |
122 | CDK1 | 0.28607063 |
123 | PRKCG | 0.26938679 |
124 | CDK14 | 0.26749971 |
125 | GRK7 | 0.26477857 |
126 | MAPKAPK5 | 0.26194128 |
127 | PLK3 | 0.26136770 |
128 | MUSK | 0.26063660 |
129 | MAPKAPK2 | 0.25195273 |
130 | STK4 | 0.25139039 |
131 | MAPK7 | 0.25087988 |
132 | ATR | 0.24671564 |
133 | PIM1 | 0.24477736 |
134 | AKT3 | 0.24284235 |
135 | CDC7 | 0.22747843 |
136 | ROCK2 | 0.22640480 |
137 | CDK8 | 0.21124054 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 5.89943148 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.87157997 |
3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.78922519 |
4 | Parkinsons disease_Homo sapiens_hsa05012 | 4.19038467 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.39130211 |
6 | Huntingtons disease_Homo sapiens_hsa05016 | 3.05282127 |
7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.92283668 |
8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.69968747 |
9 | DNA replication_Homo sapiens_hsa03030 | 2.67205227 |
10 | Spliceosome_Homo sapiens_hsa03040 | 2.47993875 |
11 | Mismatch repair_Homo sapiens_hsa03430 | 2.32836571 |
12 | Protein export_Homo sapiens_hsa03060 | 2.26009343 |
13 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.22609802 |
14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.82472694 |
15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.78099575 |
16 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.59899385 |
17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.57139681 |
18 | Homologous recombination_Homo sapiens_hsa03440 | 1.56847627 |
19 | RNA transport_Homo sapiens_hsa03013 | 1.44384187 |
20 | Base excision repair_Homo sapiens_hsa03410 | 1.41730098 |
21 | Sulfur relay system_Homo sapiens_hsa04122 | 1.35668683 |
22 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.34510955 |
23 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.32342977 |
24 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.28624376 |
25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.25807015 |
26 | Purine metabolism_Homo sapiens_hsa00230 | 1.20640757 |
27 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.19282155 |
28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.17625126 |
29 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.17217559 |
30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.09749092 |
31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05471506 |
32 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.98321062 |
33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.97467005 |
34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.91167855 |
35 | Metabolic pathways_Homo sapiens_hsa01100 | 0.87923759 |
36 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.86755245 |
37 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.83814761 |
38 | Peroxisome_Homo sapiens_hsa04146 | 0.83658257 |
39 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.81985843 |
40 | Carbon metabolism_Homo sapiens_hsa01200 | 0.81955672 |
41 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.81250055 |
42 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.78893341 |
43 | Basal transcription factors_Homo sapiens_hsa03022 | 0.78698215 |
44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.77502684 |
45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.74710948 |
46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.73065259 |
47 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.72082861 |
48 | Cell cycle_Homo sapiens_hsa04110 | 0.71759221 |
49 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.71733048 |
50 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.71150537 |
51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71122812 |
52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.70984590 |
53 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.68923411 |
54 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.68800254 |
55 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66345710 |
56 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.64960647 |
57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.63614086 |
58 | RNA degradation_Homo sapiens_hsa03018 | 0.62737752 |
59 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.61954307 |
60 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.59112999 |
61 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.58004785 |
62 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54374866 |
63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52913485 |
64 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.52183447 |
65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52139833 |
66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52128417 |
67 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.52019127 |
68 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.51838297 |
69 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.51734568 |
70 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.51351167 |
71 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.45535768 |
72 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45334707 |
73 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.43207236 |
74 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.42623488 |
75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41153885 |
76 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.40746714 |
77 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.40413742 |
78 | Histidine metabolism_Homo sapiens_hsa00340 | 0.39875754 |
79 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39388542 |
80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.39291753 |
81 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.38131956 |
82 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.38090402 |
83 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38034647 |
84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.29953940 |
85 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.29162444 |
86 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.27840568 |
87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27379735 |
88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26550587 |
89 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.25589679 |
90 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.24940085 |
91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.24836962 |
92 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.24027499 |
93 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.23456156 |
94 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.23112031 |
95 | Alcoholism_Homo sapiens_hsa05034 | 0.21394001 |
96 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.19991055 |
97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.17877929 |
98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.17823819 |
99 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.16683339 |
100 | Phototransduction_Homo sapiens_hsa04744 | 0.16567190 |
101 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.15957910 |
102 | Galactose metabolism_Homo sapiens_hsa00052 | 0.15485809 |
103 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.15423771 |
104 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.14173458 |
105 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.13943982 |
106 | Asthma_Homo sapiens_hsa05310 | 0.10340050 |
107 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.10279945 |
108 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.09670627 |
109 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.09427954 |
110 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.08914360 |
111 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.07407921 |
112 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.06779306 |