TIMM17A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.18995860
2ATP synthesis coupled proton transport (GO:0015986)5.71388285
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.71388285
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.68120255
5protein neddylation (GO:0045116)5.51067409
6proteasome assembly (GO:0043248)5.49400982
7establishment of protein localization to mitochondrial membrane (GO:0090151)5.23687272
8respiratory electron transport chain (GO:0022904)4.89530558
9termination of RNA polymerase III transcription (GO:0006386)4.77779295
10transcription elongation from RNA polymerase III promoter (GO:0006385)4.77779295
11electron transport chain (GO:0022900)4.77197535
12chaperone-mediated protein transport (GO:0072321)4.76804724
137-methylguanosine mRNA capping (GO:0006370)4.60085894
14RNA capping (GO:0036260)4.48693927
157-methylguanosine RNA capping (GO:0009452)4.48693927
16CENP-A containing nucleosome assembly (GO:0034080)4.46775984
17chromatin remodeling at centromere (GO:0031055)4.33118350
18regulation of mitochondrial translation (GO:0070129)4.31762961
19negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.29623356
20positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.14594601
21cullin deneddylation (GO:0010388)4.13880892
22L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.13762622
23purine nucleobase biosynthetic process (GO:0009113)4.05018274
24regulation of cellular amino acid metabolic process (GO:0006521)4.00710477
25rRNA modification (GO:0000154)4.00303248
26regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.99484549
27anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.99276004
28transcription elongation from RNA polymerase I promoter (GO:0006362)3.98743321
29negative regulation of ligase activity (GO:0051352)3.95448891
30negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.95448891
31ribosome assembly (GO:0042255)3.90680919
32protein complex biogenesis (GO:0070271)3.86111670
33mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.81030712
34mitochondrial respiratory chain complex I assembly (GO:0032981)3.81030712
35NADH dehydrogenase complex assembly (GO:0010257)3.81030712
36establishment of integrated proviral latency (GO:0075713)3.78737458
37termination of RNA polymerase I transcription (GO:0006363)3.78469869
38DNA replication checkpoint (GO:0000076)3.77454245
39protein deneddylation (GO:0000338)3.77148941
40L-methionine salvage (GO:0071267)3.75406479
41L-methionine biosynthetic process (GO:0071265)3.75406479
42amino acid salvage (GO:0043102)3.75406479
43histone exchange (GO:0043486)3.69884760
44transcription from RNA polymerase I promoter (GO:0006360)3.69801491
45positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.65171722
46* protein targeting to mitochondrion (GO:0006626)3.62282344
47* establishment of protein localization to mitochondrion (GO:0072655)3.60525511
48DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.52124202
49mitochondrial respiratory chain complex assembly (GO:0033108)3.50236484
50positive regulation of ligase activity (GO:0051351)3.48448995
51signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.47421583
52signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.47421583
53signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.47421583
54positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)3.45711550
55nucleobase biosynthetic process (GO:0046112)3.45660751
56intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.44322267
57signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.44322267
58* protein localization to mitochondrion (GO:0070585)3.43565488
59guanosine-containing compound biosynthetic process (GO:1901070)3.43422745
60signal transduction involved in DNA integrity checkpoint (GO:0072401)3.40939633
61signal transduction involved in DNA damage checkpoint (GO:0072422)3.40939633
62telomere maintenance via semi-conservative replication (GO:0032201)3.38866494
63transcription initiation from RNA polymerase I promoter (GO:0006361)3.38758495
64signal transduction involved in cell cycle checkpoint (GO:0072395)3.35978648
65metaphase plate congression (GO:0051310)3.31894315
66DNA double-strand break processing (GO:0000729)3.31675868
67ribosome biogenesis (GO:0042254)3.30297085
68DNA strand elongation involved in DNA replication (GO:0006271)3.27350577
69regulation of mitotic spindle checkpoint (GO:1903504)3.26946817
70regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.26946817
71blastocyst development (GO:0001824)3.25365440
72positive regulation of mitochondrial fission (GO:0090141)3.24554171
73mitochondrial RNA metabolic process (GO:0000959)3.23617292
74IMP biosynthetic process (GO:0006188)3.23460817
75exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.23180535
76GTP biosynthetic process (GO:0006183)3.23149709
77G1/S transition of mitotic cell cycle (GO:0000082)3.20740164
78cell cycle G1/S phase transition (GO:0044843)3.20740164
79regulation of ubiquitin-protein transferase activity (GO:0051438)3.20490410
80nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.20223860
81DNA replication-independent nucleosome assembly (GO:0006336)3.18969746
82DNA replication-independent nucleosome organization (GO:0034724)3.18969746
83DNA catabolic process, exonucleolytic (GO:0000738)3.18944786
84ribosomal large subunit biogenesis (GO:0042273)3.16931587
85transcription elongation from RNA polymerase II promoter (GO:0006368)3.16266403
86transcription from mitochondrial promoter (GO:0006390)3.15637791
87DNA strand elongation (GO:0022616)3.13827067
88kinetochore assembly (GO:0051382)3.13236432
89cellular component biogenesis (GO:0044085)3.12684080
90peptidyl-histidine modification (GO:0018202)3.12595460
91cytochrome complex assembly (GO:0017004)3.11461808
92establishment of viral latency (GO:0019043)3.11230870
93protein-cofactor linkage (GO:0018065)3.11019518
94mitotic metaphase plate congression (GO:0007080)3.09137785
95translation (GO:0006412)3.08891614
96regulation of cellular amine metabolic process (GO:0033238)3.08477526
97regulation of ligase activity (GO:0051340)3.08399477
98kinetochore organization (GO:0051383)3.07163611
99DNA-templated transcription, elongation (GO:0006354)3.07087869
100ribonucleoprotein complex biogenesis (GO:0022613)3.04169674
101rRNA methylation (GO:0031167)3.03102209
102antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.01767352
103formation of translation preinitiation complex (GO:0001731)3.00790651
104long-chain fatty acid biosynthetic process (GO:0042759)2.99302316
105nucleobase-containing small molecule interconversion (GO:0015949)2.99147207
106DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.97836534
107maturation of 5.8S rRNA (GO:0000460)2.97480559
108negative regulation of protein ubiquitination (GO:0031397)2.97007778
109hydrogen ion transmembrane transport (GO:1902600)2.95316623
110telomere maintenance via recombination (GO:0000722)2.95116750
111amino acid activation (GO:0043038)2.94393590
112purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.93756887
113rRNA processing (GO:0006364)2.93222316
114spliceosomal snRNP assembly (GO:0000387)2.91259795
115purine nucleoside triphosphate biosynthetic process (GO:0009145)2.87291521
116rRNA metabolic process (GO:0016072)2.86287082
117ATP biosynthetic process (GO:0006754)2.85358937
118positive regulation of viral transcription (GO:0050434)2.82395813
119response to redox state (GO:0051775)2.81964057
120UTP biosynthetic process (GO:0006228)2.78123110
121oxidative phosphorylation (GO:0006119)2.77471295
122pseudouridine synthesis (GO:0001522)2.75153512
123transcription-coupled nucleotide-excision repair (GO:0006283)2.74497655
124* mitochondrial transport (GO:0006839)2.74181081
125DNA deamination (GO:0045006)2.73752345
126antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.73694431
127respiratory chain complex IV assembly (GO:0008535)2.72964197
128NADH metabolic process (GO:0006734)2.72404476
129GMP metabolic process (GO:0046037)2.70788507
130ubiquinone biosynthetic process (GO:0006744)2.67743937
131quinone biosynthetic process (GO:1901663)2.67743937
132positive regulation of cell cycle arrest (GO:0071158)2.67542968
133DNA damage response, detection of DNA damage (GO:0042769)2.65199372

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.45224711
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.13772247
3E2F7_22180533_ChIP-Seq_HELA_Human4.69574970
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.24976393
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.14332598
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.99436520
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.82283411
8CREB1_15753290_ChIP-ChIP_HEK293T_Human3.77443873
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.74503701
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.29686018
11* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.17457134
12* MYC_18555785_ChIP-Seq_MESCs_Mouse3.08803642
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.01402219
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.00323486
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.47870604
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.43726065
17* VDR_23849224_ChIP-Seq_CD4+_Human2.34904166
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.26026279
19THAP11_20581084_ChIP-Seq_MESCs_Mouse2.25461416
20* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.20944610
21SRF_21415370_ChIP-Seq_HL-1_Mouse2.18713792
22YY1_21170310_ChIP-Seq_MESCs_Mouse2.17114581
23* PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.09626509
24ELK1_19687146_ChIP-ChIP_HELA_Human1.97555697
25DCP1A_22483619_ChIP-Seq_HELA_Human1.95654732
26FOXM1_23109430_ChIP-Seq_U2OS_Human1.89788857
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88495458
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.85782759
29FOXP3_21729870_ChIP-Seq_TREG_Human1.73993661
30* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.72714833
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72710067
32GABP_19822575_ChIP-Seq_HepG2_Human1.69474476
33ELK1_22589737_ChIP-Seq_MCF10A_Human1.69304346
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.66784376
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.66595925
36XRN2_22483619_ChIP-Seq_HELA_Human1.65619302
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.64781370
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.63969742
39* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.62147357
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.59180428
41TTF2_22483619_ChIP-Seq_HELA_Human1.56622202
42E2F1_21310950_ChIP-Seq_MCF-7_Human1.56018429
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43718703
44VDR_22108803_ChIP-Seq_LS180_Human1.41401148
45CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.39808246
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.38760906
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.38480519
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.37158533
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.35646644
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.35456134
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32892829
52POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.31636108
53MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.31083193
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.30725543
55* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.28378216
56ZNF274_21170338_ChIP-Seq_K562_Hela1.27752070
57FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.27529459
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27349009
59* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.26578523
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25067689
61* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.22237864
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.18700314
63ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15268040
64CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.14773448
65FUS_26573619_Chip-Seq_HEK293_Human1.14754394
66DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.14485510
67AR_21909140_ChIP-Seq_LNCAP_Human1.09869466
68SOX17_20123909_ChIP-Seq_XEN_Mouse1.09740853
69E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06818845
70SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.04351964
71* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98531584
72ELF1_17652178_ChIP-ChIP_JURKAT_Human0.97667938
73ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97361612
74* TAF15_26573619_Chip-Seq_HEK293_Human0.96135636
75NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.95046935
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94991765
77* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.94973811
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94605744
79SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.94304547
80KAP1_22055183_ChIP-Seq_ESCs_Mouse0.93249857
81ELF5_23300383_ChIP-Seq_T47D_Human0.92772602
82TFEB_21752829_ChIP-Seq_HELA_Human0.92364034
83MYC_18940864_ChIP-ChIP_HL60_Human0.90869862
84ER_23166858_ChIP-Seq_MCF-7_Human0.90134825
85SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.89974606
86IRF1_19129219_ChIP-ChIP_H3396_Human0.89293531
87BMI1_23680149_ChIP-Seq_NPCS_Mouse0.89063513
88FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.89033658
89CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.86081586
90KDM5A_27292631_Chip-Seq_BREAST_Human0.83759783
91* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.83187848
92POU3F2_20337985_ChIP-ChIP_501MEL_Human0.82703685
93EWS_26573619_Chip-Seq_HEK293_Human0.82493557
94PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.82209879
95GBX2_23144817_ChIP-Seq_PC3_Human0.81483487
96SOX2_16153702_ChIP-ChIP_HESCs_Human0.77395805
97EZH2_27294783_Chip-Seq_NPCs_Mouse0.76520258
98CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.76184070
99NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.75461232
100SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.75417860
101SUZ12_27294783_Chip-Seq_NPCs_Mouse0.75043938
102CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.74864940
103FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.74819720
104TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.74255937
105RBPJ_22232070_ChIP-Seq_NCS_Mouse0.73592871
106HTT_18923047_ChIP-ChIP_STHdh_Human0.72883144
107KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.70182612
108SALL4_22934838_ChIP-ChIP_CD34+_Human0.69541542
109CTBP2_25329375_ChIP-Seq_LNCAP_Human0.69504308
110NANOG_16153702_ChIP-ChIP_HESCs_Human0.69024880
111EOMES_21245162_ChIP-Seq_HESCs_Human0.68748776
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.68123474
113NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.67878522
114SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.67552432
115GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.66780993
116TP53_22573176_ChIP-Seq_HFKS_Human0.66252947
117RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.66041250
118IGF1R_20145208_ChIP-Seq_DFB_Human0.65190208
119MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.65031453
120* NFE2_27457419_Chip-Seq_LIVER_Mouse0.64599362
121ZFX_18555785_ChIP-Seq_MESCs_Mouse0.64471284
122PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.64406415
123JUN_21703547_ChIP-Seq_K562_Human0.64138287
124POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.63657023
125TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.62948444
126REST_19997604_ChIP-ChIP_NEURONS_Mouse0.62515301
127SOX2_18555785_ChIP-Seq_MESCs_Mouse0.61693783

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis4.98762167
2MP0003880_abnormal_central_pattern3.61197799
3MP0003718_maternal_effect3.22292277
4MP0001529_abnormal_vocalization3.03888278
5MP0003693_abnormal_embryo_hatching2.66194191
6MP0001905_abnormal_dopamine_level2.62194458
7MP0003646_muscle_fatigue2.44225862
8MP0008260_abnormal_autophagy2.33255921
9MP0005408_hypopigmentation2.31681493
10MP0008007_abnormal_cellular_replicative2.29333183
11MP0004957_abnormal_blastocyst_morpholog2.22895400
12MP0006276_abnormal_autonomic_nervous2.11873509
13MP0009046_muscle_twitch2.07039063
14MP0004084_abnormal_cardiac_muscle2.03776893
15MP0002938_white_spotting1.97343952
16MP0008932_abnormal_embryonic_tissue1.93350894
17MP0002163_abnormal_gland_morphology1.93027152
18MP0003136_yellow_coat_color1.91917338
19MP0008877_abnormal_DNA_methylation1.91672800
20MP0003123_paternal_imprinting1.87325059
21MP0001440_abnormal_grooming_behavior1.86201934
22MP0006035_abnormal_mitochondrial_morpho1.84816608
23MP0008875_abnormal_xenobiotic_pharmacok1.81644066
24MP0000749_muscle_degeneration1.78733761
25MP0004036_abnormal_muscle_relaxation1.74093329
26MP0006036_abnormal_mitochondrial_physio1.74021457
27MP0003950_abnormal_plasma_membrane1.72183664
28MP0002837_dystrophic_cardiac_calcinosis1.70608554
29MP0004270_analgesia1.66564523
30MP0003111_abnormal_nucleus_morphology1.65941915
31MP0002734_abnormal_mechanical_nocicepti1.64407406
32MP0003786_premature_aging1.63070970
33MP0002272_abnormal_nervous_system1.59768087
34MP0002736_abnormal_nociception_after1.57477664
35MP0004215_abnormal_myocardial_fiber1.55618462
36MP0005171_absent_coat_pigmentation1.55514215
37MP0001968_abnormal_touch/_nociception1.55217909
38MP0004145_abnormal_muscle_electrophysio1.54684546
39MP0004142_abnormal_muscle_tone1.52746657
40MP0001485_abnormal_pinna_reflex1.50168295
41MP0008057_abnormal_DNA_replication1.49603333
42MP0008058_abnormal_DNA_repair1.46298814
43MP0002064_seizures1.42470558
44MP0003315_abnormal_perineum_morphology1.41263305
45MP0001188_hyperpigmentation1.39868101
46MP0001542_abnormal_bone_strength1.37274654
47MP0000750_abnormal_muscle_regeneration1.36987975
48MP0003077_abnormal_cell_cycle1.35183947
49MP0005377_hearing/vestibular/ear_phenot1.34301777
50MP0003878_abnormal_ear_physiology1.34301777
51MP0005075_abnormal_melanosome_morpholog1.33851723
52MP0003890_abnormal_embryonic-extraembry1.31961874
53MP0009745_abnormal_behavioral_response1.31796605
54MP0000358_abnormal_cell_content/1.31626824
55MP0002095_abnormal_skin_pigmentation1.26858820
56MP0005330_cardiomyopathy1.25705972
57MP0001486_abnormal_startle_reflex1.24904930
58MP0010094_abnormal_chromosome_stability1.24675495
59MP0000747_muscle_weakness1.21884729
60MP0001764_abnormal_homeostasis1.18701104
61MP0002102_abnormal_ear_morphology1.18187378
62MP0004147_increased_porphyrin_level1.18114872
63MP0004484_altered_response_of1.17759966
64MP0005451_abnormal_body_composition1.16987216
65MP0002090_abnormal_vision1.16283796
66MP0001501_abnormal_sleep_pattern1.15819132
67MP0000350_abnormal_cell_proliferation1.15481581
68MP0001986_abnormal_taste_sensitivity1.15356099
69MP0005253_abnormal_eye_physiology1.14953150
70MP0001661_extended_life_span1.14806091
71MP0004924_abnormal_behavior1.14526697
72MP0005386_behavior/neurological_phenoty1.14526697
73MP0002876_abnormal_thyroid_physiology1.13874478
74MP0004742_abnormal_vestibular_system1.13142049
75MP0000751_myopathy1.12739237
76MP0002735_abnormal_chemical_nociception1.11427287
77MP0002067_abnormal_sensory_capabilities1.09537774
78MP0002572_abnormal_emotion/affect_behav1.08979450
79MP0001727_abnormal_embryo_implantation1.08274503
80MP0008872_abnormal_physiological_respon1.07004737
81MP0005423_abnormal_somatic_nervous1.06130457
82MP0005084_abnormal_gallbladder_morpholo1.05887543
83MP0001697_abnormal_embryo_size1.05437035
84MP0000372_irregular_coat_pigmentation1.05041613
85MP0003635_abnormal_synaptic_transmissio1.04986251
86MP0003137_abnormal_impulse_conducting1.04645804
87MP0003938_abnormal_ear_development1.04021737
88MP0005379_endocrine/exocrine_gland_phen1.03585623
89MP0000015_abnormal_ear_pigmentation1.01772782
90MP0000566_synostosis1.01243752
91MP0001970_abnormal_pain_threshold1.00365611
92MP0005395_other_phenotype1.00006977
93MP0003221_abnormal_cardiomyocyte_apopto0.99915597
94MP0001929_abnormal_gametogenesis0.97082756
95MP0009697_abnormal_copulation0.95621614
96MP0001963_abnormal_hearing_physiology0.91587762
97MP0001324_abnormal_eye_pigmentation0.91019553
98MP0003879_abnormal_hair_cell0.90759321
99MP0002638_abnormal_pupillary_reflex0.89651971
100MP0002106_abnormal_muscle_physiology0.89573359
101MP0006292_abnormal_olfactory_placode0.88947790
102MP0005620_abnormal_muscle_contractility0.87655753
103MP0001293_anophthalmia0.87020274
104MP0002972_abnormal_cardiac_muscle0.86645490
105MP0003195_calcinosis0.86471404
106MP0000647_abnormal_sebaceous_gland0.86395226
107MP0003567_abnormal_fetal_cardiomyocyte0.86325652
108MP0000313_abnormal_cell_death0.83913539
109MP0000920_abnormal_myelination0.83576238
110MP0005551_abnormal_eye_electrophysiolog0.83394023
111MP0006138_congestive_heart_failure0.83393233
112MP0002080_prenatal_lethality0.82243037
113MP0010030_abnormal_orbit_morphology0.82124822
114MP0009379_abnormal_foot_pigmentation0.81780746
115MP0005174_abnormal_tail_pigmentation0.81675810
116MP0006072_abnormal_retinal_apoptosis0.81662633
117MP0002332_abnormal_exercise_endurance0.81521627
118MP0003186_abnormal_redox_activity0.81375331
119MP0004043_abnormal_pH_regulation0.80938387
120MP0005410_abnormal_fertilization0.80349969
121MP0005266_abnormal_metabolism0.79936675
122MP0001730_embryonic_growth_arrest0.79616926
123MP0002063_abnormal_learning/memory/cond0.79504790
124MP0002160_abnormal_reproductive_system0.79470520
125MP0005389_reproductive_system_phenotype0.79029691
126MP0003941_abnormal_skin_development0.78695270
127MP0002229_neurodegeneration0.78477547
128MP0000653_abnormal_sex_gland0.78336831
129MP0003937_abnormal_limbs/digits/tail_de0.77563329
130MP0005380_embryogenesis_phenotype0.77382085
131MP0001672_abnormal_embryogenesis/_devel0.77382085
132MP0005369_muscle_phenotype0.77147596
133MP0002210_abnormal_sex_determination0.76929437
134MP0002234_abnormal_pharynx_morphology0.76673383
135MP0005332_abnormal_amino_acid0.76552956
136MP0002066_abnormal_motor_capabilities/c0.75592631
137MP0001145_abnormal_male_reproductive0.74220053
138MP0002085_abnormal_embryonic_tissue0.73183176
139MP0003011_delayed_dark_adaptation0.71039729
140MP0002084_abnormal_developmental_patter0.70164047
141MP0000371_diluted_coat_color0.68502502
142MP0001881_abnormal_mammary_gland0.67359779
143MP0001119_abnormal_female_reproductive0.66830161
144MP0005187_abnormal_penis_morphology0.64203746
145MP0001853_heart_inflammation0.63651970
146MP0002282_abnormal_trachea_morphology0.63230500
147MP0005197_abnormal_uvea_morphology0.60357270
148MP0010307_abnormal_tumor_latency0.58677150
149MP0000427_abnormal_hair_cycle0.58569616
150MP0001186_pigmentation_phenotype0.58188052
151MP0004233_abnormal_muscle_weight0.57068681
152MP0008995_early_reproductive_senescence0.56916367
153MP0000569_abnormal_digit_pigmentation0.55826688
154MP0001984_abnormal_olfaction0.53149514
155MP0002088_abnormal_embryonic_growth/wei0.53093771
156MP0003698_abnormal_male_reproductive0.52921154

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.40766682
2Abnormal mitochondria in muscle tissue (HP:0008316)4.80392474
3Mitochondrial inheritance (HP:0001427)4.79128221
4Progressive macrocephaly (HP:0004481)4.43155664
5Increased CSF lactate (HP:0002490)4.36566346
6Increased serum pyruvate (HP:0003542)4.33265671
7Abnormality of glycolysis (HP:0004366)4.33265671
8Cerebral hypomyelination (HP:0006808)4.28535565
9Hepatocellular necrosis (HP:0001404)4.21894322
10Acute encephalopathy (HP:0006846)4.19063610
11Increased hepatocellular lipid droplets (HP:0006565)3.86377556
12Hepatic necrosis (HP:0002605)3.65273907
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.50559125
14Breast hypoplasia (HP:0003187)3.38417116
15Carpal bone hypoplasia (HP:0001498)3.37883217
16Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.35014509
17Lipid accumulation in hepatocytes (HP:0006561)3.30187358
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.25009647
193-Methylglutaconic aciduria (HP:0003535)3.21678207
20Increased serum lactate (HP:0002151)3.13599242
21Birth length less than 3rd percentile (HP:0003561)3.11881552
22Respiratory failure (HP:0002878)3.09560124
23Renal Fanconi syndrome (HP:0001994)2.98127107
24Type I transferrin isoform profile (HP:0003642)2.97449161
25Abnormality of methionine metabolism (HP:0010901)2.97075277
26Exercise intolerance (HP:0003546)2.91979479
27Lactic acidosis (HP:0003128)2.89774771
28Methylmalonic acidemia (HP:0002912)2.89561617
29Parakeratosis (HP:0001036)2.78295376
30Leukodystrophy (HP:0002415)2.76106714
31Cerebral edema (HP:0002181)2.74021752
32Degeneration of anterior horn cells (HP:0002398)2.70256214
33Abnormality of the anterior horn cell (HP:0006802)2.70256214
34CNS hypomyelination (HP:0003429)2.69459046
35Rough bone trabeculation (HP:0100670)2.69023815
36Muscle fiber splitting (HP:0003555)2.65859147
37Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.65123249
38Decreased activity of mitochondrial respiratory chain (HP:0008972)2.65123249
39Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.64276486
40Abnormality of alanine metabolism (HP:0010916)2.64276486
41Hyperalaninemia (HP:0003348)2.64276486
42Optic disc pallor (HP:0000543)2.63706750
43CNS demyelination (HP:0007305)2.59014943
44Reduced antithrombin III activity (HP:0001976)2.57685829
45Pheochromocytoma (HP:0002666)2.57240619
46Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.56189147
47Increased intramyocellular lipid droplets (HP:0012240)2.54342475
48Neuroendocrine neoplasm (HP:0100634)2.50604185
49Irregular epiphyses (HP:0010582)2.46055455
50Abnormal glycosylation (HP:0012345)2.45612676
51Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.45612676
52Abnormal protein N-linked glycosylation (HP:0012347)2.45612676
53Abnormal protein glycosylation (HP:0012346)2.45612676
54Aplastic anemia (HP:0001915)2.44966356
55Abnormality of the labia minora (HP:0012880)2.44943496
56Respiratory difficulties (HP:0002880)2.43288968
57Congenital, generalized hypertrichosis (HP:0004540)2.39636538
58Abnormality of aspartate family amino acid metabolism (HP:0010899)2.39258687
59Emotional lability (HP:0000712)2.31613116
60Meckel diverticulum (HP:0002245)2.31459091
61Generalized aminoaciduria (HP:0002909)2.30837540
62Exertional dyspnea (HP:0002875)2.25458980
63Aplasia/Hypoplasia involving the musculature (HP:0001460)2.23508433
64Delusions (HP:0000746)2.22610241
65Aplasia/Hypoplasia of the uvula (HP:0010293)2.22402318
66Abnormality of the ileum (HP:0001549)2.22215965
67Macrocytic anemia (HP:0001972)2.21202509
68Congenital ichthyosiform erythroderma (HP:0007431)2.18031913
69Abnormality of the pons (HP:0007361)2.16699278
70Microvesicular hepatic steatosis (HP:0001414)2.14748442
71Abnormal trabecular bone morphology (HP:0100671)2.14685059
72Abnormality of serum amino acid levels (HP:0003112)2.14359123
73Areflexia of lower limbs (HP:0002522)2.14091890
74Hypoplasia of the pons (HP:0012110)2.13746059
75Chromosomal breakage induced by crosslinking agents (HP:0003221)2.11787867
76Oral leukoplakia (HP:0002745)2.10258368
77Abnormal lung lobation (HP:0002101)2.09109012
78Megaloblastic anemia (HP:0001889)2.08711569
79Focal motor seizures (HP:0011153)2.08570109
80Postnatal microcephaly (HP:0005484)2.08026023
81Hypoplasia of the fovea (HP:0007750)2.07249409
82Aplasia/Hypoplasia of the fovea (HP:0008060)2.07249409
83Abnormality of chromosome stability (HP:0003220)2.05055418
84Hypoplasia of the capital femoral epiphysis (HP:0003090)2.04873694
85Unsteady gait (HP:0002317)2.04306884
86Progressive external ophthalmoplegia (HP:0000590)2.03643092
87Chromsome breakage (HP:0040012)2.00613128
88Ureteral duplication (HP:0000073)1.99017267
89Abnormality of the preputium (HP:0100587)1.98777948
90Increased muscle lipid content (HP:0009058)1.97969588
91Muscle hypertrophy of the lower extremities (HP:0008968)1.96631763
92Multiple enchondromatosis (HP:0005701)1.95715387
93Abnormality of renal resorption (HP:0011038)1.95645237
94Secondary amenorrhea (HP:0000869)1.94993491
95X-linked dominant inheritance (HP:0001423)1.94854984
96Absent radius (HP:0003974)1.94741622
97Short tibia (HP:0005736)1.93528080
98Abnormality of the fovea (HP:0000493)1.92384386
99Volvulus (HP:0002580)1.91026676
100Pancreatic cysts (HP:0001737)1.89020807
101External ophthalmoplegia (HP:0000544)1.86735212
102Lethargy (HP:0001254)1.85207295
103Pancytopenia (HP:0001876)1.84581998
104Absent forearm bone (HP:0003953)1.83417262
105Aplasia involving forearm bones (HP:0009822)1.83417262
106Abnormality of the umbilical cord (HP:0010881)1.82528955
107Testicular atrophy (HP:0000029)1.81974533
108Absent epiphyses (HP:0010577)1.81894841
109Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.81894841
110Aplasia/hypoplasia of the uterus (HP:0008684)1.81766117
111Sensory axonal neuropathy (HP:0003390)1.80835831
112Adrenal hypoplasia (HP:0000835)1.80236669
113Rimmed vacuoles (HP:0003805)1.79117708
114Methylmalonic aciduria (HP:0012120)1.78910839
115Abnormality of sulfur amino acid metabolism (HP:0004339)1.78463880
116Double outlet right ventricle (HP:0001719)1.77998294
117Congenital malformation of the right heart (HP:0011723)1.77998294
118Pancreatic fibrosis (HP:0100732)1.76974271
119Molar tooth sign on MRI (HP:0002419)1.76894553
120Abnormality of midbrain morphology (HP:0002418)1.76894553
121Amniotic constriction ring (HP:0009775)1.76687435
122Abnormality of placental membranes (HP:0011409)1.76687435
123Patchy hypopigmentation of hair (HP:0011365)1.75848626
124Duodenal stenosis (HP:0100867)1.75745467
125Small intestinal stenosis (HP:0012848)1.75745467
126Impulsivity (HP:0100710)1.74863771
127Abnormality of the vitamin B12 metabolism (HP:0004341)1.73942691
128Medial flaring of the eyebrow (HP:0010747)1.73619954
129Calf muscle hypertrophy (HP:0008981)1.72790693
130Abnormal number of erythroid precursors (HP:0012131)1.71704523
131Aplasia/Hypoplasia of the tibia (HP:0005772)1.71618045
132Hyperglycinemia (HP:0002154)1.68210797
133Sparse eyelashes (HP:0000653)1.67801615
134Stenosis of the external auditory canal (HP:0000402)1.67734631
135Palpitations (HP:0001962)1.64850985
136Abnormality of homocysteine metabolism (HP:0010919)1.64668146
137Autoamputation (HP:0001218)1.64405137
138Aplasia/Hypoplasia of the patella (HP:0006498)1.63987254
139Spastic paraparesis (HP:0002313)1.63793928
140Patellar aplasia (HP:0006443)1.63716809
141Premature ovarian failure (HP:0008209)1.63632339
142Aplasia of the musculature (HP:0100854)1.62856285
143Split foot (HP:0001839)1.60664620
144Glycosuria (HP:0003076)1.59410058
145Abnormality of urine glucose concentration (HP:0011016)1.59410058
146Progressive muscle weakness (HP:0003323)1.58767853
147Abnormal hair whorl (HP:0010721)1.58696508

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.63838127
2VRK23.09426861
3STK163.07411337
4EIF2AK12.90204079
5WEE12.78357495
6PNCK2.58561312
7AKT32.50105522
8CDC72.47706469
9NME12.45436449
10TSSK62.45148728
11TRIM282.37941643
12STK392.32587481
13PLK42.12363999
14ARAF2.09953882
15SRPK12.08086111
16CASK1.90518700
17PBK1.85300536
18OXSR11.85193992
19EIF2AK31.83848640
20ZAK1.82459328
21NME21.76377767
22BRSK21.68068761
23BCR1.66907621
24PINK11.58480790
25PDK31.52559591
26PDK41.52559591
27PLK31.52197061
28OBSCN1.51635489
29MKNK11.48488119
30EPHA21.43373285
31MAP3K121.39713761
32MKNK21.39654293
33VRK11.39147400
34PDK21.33266395
35MST41.33243733
36STK38L1.30716276
37BRAF1.30338764
38CCNB11.27430184
39LIMK11.18147183
40MYLK1.16488360
41ERBB31.10321362
42BRSK11.08685284
43PLK11.05621707
44NEK61.05207468
45PLK21.02753451
46PIM20.99674703
47TNIK0.99642030
48TTK0.97373147
49AURKA0.95519913
50WNK40.94719252
51TAF10.91957734
52NEK10.91179848
53MUSK0.90243358
54EIF2AK20.89410143
55MAP2K70.87288386
56GRK70.84768478
57TLK10.80966742
58MAPKAPK50.80960968
59STK240.80347489
60IRAK30.79749370
61CSNK1G30.79748154
62WNK30.77557511
63CAMK2D0.77382435
64CAMK2B0.73771058
65ATR0.73514161
66TESK20.70593963
67ERBB40.68415416
68STK30.67377060
69MARK10.67132691
70ADRBK20.66943257
71GRK50.65970218
72DYRK20.65663124
73MAP4K20.64954414
74CHEK20.61523994
75FRK0.61013014
76CAMK2G0.59143740
77EPHA40.58986936
78SIK30.58703304
79BCKDK0.58639356
80BMPR1B0.58357492
81ALK0.57879984
82CDK190.57414694
83PRKCG0.57210420
84LATS20.56743923
85ACVR1B0.55661110
86GRK10.54897362
87PAK40.54651458
88CAMK2A0.53014296
89CDK70.52833776
90MAP3K40.52790657
91BMPR20.52679284
92PAK10.52547845
93AURKB0.51733103
94STK40.51386726
95ABL20.51067024
96CHEK10.50616689
97ATM0.50234975
98NUAK10.50229002
99TGFBR20.50037975
100CAMKK20.49040857
101CDK30.48551519
102CSNK2A10.47837596
103CSNK1G10.47387087
104RPS6KA50.47256362
105PRKCE0.47241618
106PRKCI0.47080334
107CSNK2A20.46856791
108INSRR0.45728372
109ILK0.44541803
110MST1R0.44466833
111CDK140.43278404
112CLK10.42662392
113CSNK1G20.41860631
114TGFBR10.41295457
115PKN10.39314580
116CSNK1A10.38925814
117NTRK30.36478782
118CSNK1E0.36191445
119NEK20.34906347
120PASK0.34703976
121CSNK1A1L0.34327788
122DAPK10.33556651
123CDK180.32378391
124PRKACA0.32280024
125STK100.31388240
126ROCK20.30451428
127PAK30.29826675
128CDK150.29113363
129MINK10.28723074
130CDK10.28591363
131CDK80.27076891
132ADRBK10.25315164
133FGFR10.23357600

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.83127132
2Oxidative phosphorylation_Homo sapiens_hsa001904.63409997
3RNA polymerase_Homo sapiens_hsa030204.16392876
4Parkinsons disease_Homo sapiens_hsa050123.92136744
5Vitamin B6 metabolism_Homo sapiens_hsa007503.40856308
6Huntingtons disease_Homo sapiens_hsa050163.02928237
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.01471425
8Alzheimers disease_Homo sapiens_hsa050102.76163361
9Ribosome_Homo sapiens_hsa030102.68045369
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.47909371
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.19715291
12Cardiac muscle contraction_Homo sapiens_hsa042602.10705498
13Pyrimidine metabolism_Homo sapiens_hsa002401.96213888
14One carbon pool by folate_Homo sapiens_hsa006701.93447917
15Collecting duct acid secretion_Homo sapiens_hsa049661.92470095
16Basal transcription factors_Homo sapiens_hsa030221.86906352
17RNA transport_Homo sapiens_hsa030131.85598772
18Protein export_Homo sapiens_hsa030601.85333380
19Spliceosome_Homo sapiens_hsa030401.62303566
20Regulation of autophagy_Homo sapiens_hsa041401.60764742
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59036787
22Homologous recombination_Homo sapiens_hsa034401.58316581
23Fatty acid elongation_Homo sapiens_hsa000621.52917347
24Purine metabolism_Homo sapiens_hsa002301.50735646
25Nucleotide excision repair_Homo sapiens_hsa034201.42673657
26Mismatch repair_Homo sapiens_hsa034301.31457713
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.31363192
28DNA replication_Homo sapiens_hsa030301.28920963
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23703767
30Sulfur relay system_Homo sapiens_hsa041221.22167225
31Steroid biosynthesis_Homo sapiens_hsa001001.19646321
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.16764396
33Nicotine addiction_Homo sapiens_hsa050331.10750341
34Vibrio cholerae infection_Homo sapiens_hsa051101.09394073
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.02893405
36RNA degradation_Homo sapiens_hsa030181.02651936
37Ether lipid metabolism_Homo sapiens_hsa005651.00812919
38Cell cycle_Homo sapiens_hsa041100.98146266
39Selenocompound metabolism_Homo sapiens_hsa004500.97552140
40Synaptic vesicle cycle_Homo sapiens_hsa047210.96734919
41Fanconi anemia pathway_Homo sapiens_hsa034600.95960902
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.95721713
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.94113525
44Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.89935584
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.89734878
46Rheumatoid arthritis_Homo sapiens_hsa053230.83935000
47Oocyte meiosis_Homo sapiens_hsa041140.83842971
48Metabolic pathways_Homo sapiens_hsa011000.80794965
49Linoleic acid metabolism_Homo sapiens_hsa005910.80712674
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.80201615
51Arachidonic acid metabolism_Homo sapiens_hsa005900.78513593
52Epstein-Barr virus infection_Homo sapiens_hsa051690.72191030
53Phototransduction_Homo sapiens_hsa047440.70608802
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.68867045
55Carbon metabolism_Homo sapiens_hsa012000.67094829
56SNARE interactions in vesicular transport_Homo sapiens_hsa041300.65929763
57Glycerophospholipid metabolism_Homo sapiens_hsa005640.64052748
58Sphingolipid metabolism_Homo sapiens_hsa006000.62984613
59Pentose phosphate pathway_Homo sapiens_hsa000300.62368309
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62348514
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.60802623
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.59624508
63Folate biosynthesis_Homo sapiens_hsa007900.59540711
64Glutathione metabolism_Homo sapiens_hsa004800.58784273
65Base excision repair_Homo sapiens_hsa034100.58407860
66Peroxisome_Homo sapiens_hsa041460.58319946
67Fructose and mannose metabolism_Homo sapiens_hsa000510.57835119
68Non-homologous end-joining_Homo sapiens_hsa034500.55996963
69Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55885422
70N-Glycan biosynthesis_Homo sapiens_hsa005100.54955203
71Caffeine metabolism_Homo sapiens_hsa002320.54271638
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.54152931
73Sulfur metabolism_Homo sapiens_hsa009200.53375455
74Serotonergic synapse_Homo sapiens_hsa047260.53242203
75Pyruvate metabolism_Homo sapiens_hsa006200.52368854
76Tryptophan metabolism_Homo sapiens_hsa003800.51213068
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.50863307
78Nitrogen metabolism_Homo sapiens_hsa009100.49900097
79Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48723056
802-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.48561449
81Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.48161905
82Taste transduction_Homo sapiens_hsa047420.46652754
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45434204
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43841227
85Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43015375
86Arginine and proline metabolism_Homo sapiens_hsa003300.42513072
87Fatty acid metabolism_Homo sapiens_hsa012120.42382032
88Chemical carcinogenesis_Homo sapiens_hsa052040.41446920
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40049872
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38914601
91GABAergic synapse_Homo sapiens_hsa047270.38780768
92Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.38690102
93Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.38511581
94Butanoate metabolism_Homo sapiens_hsa006500.38147150
95p53 signaling pathway_Homo sapiens_hsa041150.36606567
96mRNA surveillance pathway_Homo sapiens_hsa030150.35931293
97Fatty acid degradation_Homo sapiens_hsa000710.35051686
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34979285
99Propanoate metabolism_Homo sapiens_hsa006400.32800359
100Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32666900
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.32196736
102Primary bile acid biosynthesis_Homo sapiens_hsa001200.32123057
103Vitamin digestion and absorption_Homo sapiens_hsa049770.31768797
104Circadian rhythm_Homo sapiens_hsa047100.31278281
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28978282
106Autoimmune thyroid disease_Homo sapiens_hsa053200.28773466
107Biosynthesis of amino acids_Homo sapiens_hsa012300.28281455
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28032634
109Phagosome_Homo sapiens_hsa041450.27449401
110Mineral absorption_Homo sapiens_hsa049780.26841305
111Amphetamine addiction_Homo sapiens_hsa050310.25381347
112Tight junction_Homo sapiens_hsa045300.24791231
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.23506880
114beta-Alanine metabolism_Homo sapiens_hsa004100.23022567
115Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.22289125
116Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.21500260
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.20517121
118Dilated cardiomyopathy_Homo sapiens_hsa054140.19266839
119Morphine addiction_Homo sapiens_hsa050320.18940254
120Calcium signaling pathway_Homo sapiens_hsa040200.18517185
121Retinol metabolism_Homo sapiens_hsa008300.17078239
122TGF-beta signaling pathway_Homo sapiens_hsa043500.15003620
123Legionellosis_Homo sapiens_hsa051340.14638220
124Long-term depression_Homo sapiens_hsa047300.14636082
125Graft-versus-host disease_Homo sapiens_hsa053320.12816736
126Tyrosine metabolism_Homo sapiens_hsa003500.11481819
127Glutamatergic synapse_Homo sapiens_hsa047240.11268258
128Type I diabetes mellitus_Homo sapiens_hsa049400.09322013
129Dopaminergic synapse_Homo sapiens_hsa047280.08778112
130Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.07680713

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