TIMM9P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA double-strand break processing (GO:0000729)6.40367118
2regulation of mitochondrial translation (GO:0070129)5.34186659
3piRNA metabolic process (GO:0034587)4.51642180
4regulation of mitotic spindle checkpoint (GO:1903504)4.48804255
5regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)4.48804255
6heparin biosynthetic process (GO:0030210)4.37743448
7heparin metabolic process (GO:0030202)4.37743448
8inositol phosphate catabolic process (GO:0071545)4.32542053
9rRNA catabolic process (GO:0016075)4.26478766
10neural tube formation (GO:0001841)4.25637513
11ubiquinone biosynthetic process (GO:0006744)4.25096707
12histone H2A acetylation (GO:0043968)4.17662385
13ubiquinone metabolic process (GO:0006743)4.12174726
14DNA methylation involved in gamete generation (GO:0043046)3.86489894
15male meiosis (GO:0007140)3.76877199
16DNA catabolic process, exonucleolytic (GO:0000738)3.76140807
17synapsis (GO:0007129)3.67931727
18phosphorylated carbohydrate dephosphorylation (GO:0046838)3.65643633
19inositol phosphate dephosphorylation (GO:0046855)3.65643633
20microtubule depolymerization (GO:0007019)3.64875112
21regulation of glucokinase activity (GO:0033131)3.52850109
22regulation of hexokinase activity (GO:1903299)3.52850109
23sleep (GO:0030431)3.50708919
24cellular response to interleukin-15 (GO:0071350)3.47138132
25presynaptic membrane organization (GO:0097090)3.45907026
26quinone biosynthetic process (GO:1901663)3.43166869
27glyoxylate metabolic process (GO:0046487)3.38897226
28protein neddylation (GO:0045116)3.26951123
29regulation of timing of cell differentiation (GO:0048505)3.24690320
30exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.23434939
31mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.20480128
32termination of RNA polymerase III transcription (GO:0006386)3.19818685
33transcription elongation from RNA polymerase III promoter (GO:0006385)3.19818685
34positive regulation of cell cycle checkpoint (GO:1901978)3.18611858
35mitochondrion distribution (GO:0048311)3.15683785
36tryptophan metabolic process (GO:0006568)3.13797375
37positive regulation of cardiac muscle cell differentiation (GO:2000727)3.10191138
38polyol catabolic process (GO:0046174)3.08252612
39DNA integration (GO:0015074)3.04785362
40regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.04163488
41L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.04041028
42protein K11-linked deubiquitination (GO:0035871)3.04015220
43male meiosis I (GO:0007141)3.01726496
44protein complex biogenesis (GO:0070271)3.01397024
45ncRNA catabolic process (GO:0034661)3.01250056
46nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.00901146
47negative regulation of meiotic cell cycle (GO:0051447)2.95933929
48chromatin remodeling at centromere (GO:0031055)2.93398746
49mitochondrial respiratory chain complex assembly (GO:0033108)2.92885151
50indolalkylamine metabolic process (GO:0006586)2.92208988
51peptidyl-histidine modification (GO:0018202)2.91735018
52interferon-gamma production (GO:0032609)2.90994305
53mitochondrion morphogenesis (GO:0070584)2.88722979
54regulation of nuclear cell cycle DNA replication (GO:0033262)2.88251355
55amino acid salvage (GO:0043102)2.87243397
56L-methionine salvage (GO:0071267)2.87243397
57L-methionine biosynthetic process (GO:0071265)2.87243397
58regulation of development, heterochronic (GO:0040034)2.87028455
59intra-S DNA damage checkpoint (GO:0031573)2.84813057
60recombinational repair (GO:0000725)2.83172607
61protein-cofactor linkage (GO:0018065)2.82759632
62mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.82448874
63mitochondrial respiratory chain complex I assembly (GO:0032981)2.82448874
64NADH dehydrogenase complex assembly (GO:0010257)2.82448874
65non-recombinational repair (GO:0000726)2.81904212
66double-strand break repair via nonhomologous end joining (GO:0006303)2.81904212
67epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.81099307
68DNA replication-dependent nucleosome organization (GO:0034723)2.80946717
69DNA replication-dependent nucleosome assembly (GO:0006335)2.80946717
70double-strand break repair via homologous recombination (GO:0000724)2.80842386
71ventricular trabecula myocardium morphogenesis (GO:0003222)2.80741875
72pseudouridine synthesis (GO:0001522)2.74221058
73rRNA transcription (GO:0009303)2.72298681
74RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.72236267
75negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.71155600
76histone exchange (GO:0043486)2.70741746
77CENP-A containing nucleosome assembly (GO:0034080)2.69302753
78meiotic nuclear division (GO:0007126)2.67932639
79transcription from RNA polymerase III promoter (GO:0006383)2.66259754
80transcription from mitochondrial promoter (GO:0006390)2.64993373
81postreplication repair (GO:0006301)2.64024305
82DNA damage response, detection of DNA damage (GO:0042769)2.63900801
83mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.63357489
84telomere maintenance via telomerase (GO:0007004)2.62211174
85chromosome organization involved in meiosis (GO:0070192)2.58965417
86spliceosomal snRNP assembly (GO:0000387)2.55614816
87adenosine metabolic process (GO:0046085)2.55506773
88centriole replication (GO:0007099)2.55083908
89lysine catabolic process (GO:0006554)2.53851443
90lysine metabolic process (GO:0006553)2.53851443
91negative regulation of DNA-dependent DNA replication (GO:2000104)2.52889089
92regulation of spindle checkpoint (GO:0090231)2.51534720
93translesion synthesis (GO:0019985)2.51482308
94epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.50868691
95methionine biosynthetic process (GO:0009086)2.50152047
96proteasome assembly (GO:0043248)2.47890697
97positive regulation of mitochondrial fission (GO:0090141)2.47721954
98sequestering of actin monomers (GO:0042989)2.47712716
99GTP biosynthetic process (GO:0006183)2.47350041
100cullin deneddylation (GO:0010388)2.47019021

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.01376235
2ZNF274_21170338_ChIP-Seq_K562_Hela3.52099999
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.48328420
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.88326584
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.81320634
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.76372361
7IGF1R_20145208_ChIP-Seq_DFB_Human2.67746494
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.67228886
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.66209146
10FUS_26573619_Chip-Seq_HEK293_Human2.50335551
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.40367214
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.33299910
13TAF15_26573619_Chip-Seq_HEK293_Human2.31996665
14CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.27916235
15ELK1_19687146_ChIP-ChIP_HELA_Human2.10582942
16EWS_26573619_Chip-Seq_HEK293_Human2.08453236
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.07316909
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.99519198
19E2F4_17652178_ChIP-ChIP_JURKAT_Human1.99176855
20RBPJ_22232070_ChIP-Seq_NCS_Mouse1.88996119
21SALL1_21062744_ChIP-ChIP_HESCs_Human1.87062690
22P300_19829295_ChIP-Seq_ESCs_Human1.85526537
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.85198891
24ER_23166858_ChIP-Seq_MCF-7_Human1.75355681
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.74464557
26MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.74389377
27CREB1_15753290_ChIP-ChIP_HEK293T_Human1.72571771
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71036985
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.66775542
30VDR_22108803_ChIP-Seq_LS180_Human1.64741031
31VDR_23849224_ChIP-Seq_CD4+_Human1.62392911
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.58914285
33CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.57699473
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57570473
35AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56842527
36GBX2_23144817_ChIP-Seq_PC3_Human1.54723508
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.54472412
38TP53_22573176_ChIP-Seq_HFKS_Human1.53160992
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52537099
40BCAT_22108803_ChIP-Seq_LS180_Human1.51262700
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.51031437
42BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.49138272
43UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.49072749
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47752145
45ESR1_15608294_ChIP-ChIP_MCF-7_Human1.44457158
46CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.44224941
47JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42633387
48MYC_18940864_ChIP-ChIP_HL60_Human1.41660833
49POU5F1_16153702_ChIP-ChIP_HESCs_Human1.40940405
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40809697
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.38371163
52SMAD4_21799915_ChIP-Seq_A2780_Human1.38167061
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.37785712
54RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37735944
55TCF4_23295773_ChIP-Seq_U87_Human1.37235047
56ETS1_20019798_ChIP-Seq_JURKAT_Human1.32912767
57SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30814601
58SUZ12_27294783_Chip-Seq_NPCs_Mouse1.30659310
59GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.29681369
60NANOG_18555785_Chip-Seq_ESCs_Mouse1.28965327
61MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.28656751
62TCF4_22108803_ChIP-Seq_LS180_Human1.27088132
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.26936036
64AR_25329375_ChIP-Seq_VCAP_Human1.26571098
65EZH2_27294783_Chip-Seq_NPCs_Mouse1.25248681
66NFE2_27457419_Chip-Seq_LIVER_Mouse1.23176641
67SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20034896
68CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19083528
69FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17549758
70TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.16601323
71ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16519950
72STAT3_23295773_ChIP-Seq_U87_Human1.14876093
73RUNX2_22187159_ChIP-Seq_PCA_Human1.14383342
74E2F7_22180533_ChIP-Seq_HELA_Human1.13468784
75OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12988086
76FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.12949083
77RNF2_27304074_Chip-Seq_NSC_Mouse1.10470078
78TAL1_26923725_Chip-Seq_HPCs_Mouse1.10176065
79SMAD4_21741376_ChIP-Seq_EPCs_Human1.09594811
80P53_22387025_ChIP-Seq_ESCs_Mouse1.09055760
81CBP_20019798_ChIP-Seq_JUKART_Human1.08103577
82IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08103577
83CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07288385
84SRF_21415370_ChIP-Seq_HL-1_Mouse1.06353158
85CRX_20693478_ChIP-Seq_RETINA_Mouse1.05141389
86EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.04137990
87NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03733581
88SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.02590633
89DCP1A_22483619_ChIP-Seq_HELA_Human1.02366878
90CMYC_18555785_Chip-Seq_ESCs_Mouse1.01929586
91NOTCH1_21737748_ChIP-Seq_TLL_Human1.01347766
92KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.00766040
93EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00698861
94FLI1_21867929_ChIP-Seq_TH2_Mouse1.00127343
95E2F1_18555785_Chip-Seq_ESCs_Mouse0.99003979
96P300_18555785_Chip-Seq_ESCs_Mouse0.98276070
97KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97610353
98SALL4_22934838_ChIP-ChIP_CD34+_Human0.97606950
99PCGF2_27294783_Chip-Seq_NPCs_Mouse0.94518647
100OCT4_21477851_ChIP-Seq_ESCs_Mouse0.93931277

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.91898429
2MP0002102_abnormal_ear_morphology3.86645879
3MP0004043_abnormal_pH_regulation3.80444927
4MP0008877_abnormal_DNA_methylation3.05285179
5MP0005360_urolithiasis2.90195449
6MP0002736_abnormal_nociception_after2.90094113
7MP0005171_absent_coat_pigmentation2.73320982
8MP0001968_abnormal_touch/_nociception2.52606390
9MP0008058_abnormal_DNA_repair2.29237717
10MP0006054_spinal_hemorrhage2.24732383
11MP0003718_maternal_effect2.14669213
12MP0004885_abnormal_endolymph2.13504749
13MP0010094_abnormal_chromosome_stability2.03429283
14MP0005253_abnormal_eye_physiology2.01994644
15MP0002822_catalepsy1.99669268
16MP0000569_abnormal_digit_pigmentation1.99177362
17MP0009697_abnormal_copulation1.96537875
18MP0006292_abnormal_olfactory_placode1.93235995
19MP0001188_hyperpigmentation1.89559075
20MP0003195_calcinosis1.88332500
21MP0005623_abnormal_meninges_morphology1.82851395
22MP0005174_abnormal_tail_pigmentation1.78513268
23MP0004147_increased_porphyrin_level1.75993768
24MP0003693_abnormal_embryo_hatching1.73605549
25MP0000372_irregular_coat_pigmentation1.72405420
26MP0005551_abnormal_eye_electrophysiolog1.69121996
27MP0005503_abnormal_tendon_morphology1.66902788
28MP0001501_abnormal_sleep_pattern1.61531755
29MP0006072_abnormal_retinal_apoptosis1.60337577
30MP0005075_abnormal_melanosome_morpholog1.59691198
31MP0002653_abnormal_ependyma_morphology1.56097769
32MP0003890_abnormal_embryonic-extraembry1.53531140
33MP0005187_abnormal_penis_morphology1.48239741
34MP0008057_abnormal_DNA_replication1.47184513
35MP0000371_diluted_coat_color1.43846583
36MP0002095_abnormal_skin_pigmentation1.35324254
37MP0002160_abnormal_reproductive_system1.34406205
38MP0000465_gastrointestinal_hemorrhage1.34366423
39MP0005646_abnormal_pituitary_gland1.33331618
40MP0001270_distended_abdomen1.32900023
41MP0000647_abnormal_sebaceous_gland1.31910569
42MP0002751_abnormal_autonomic_nervous1.27269359
43MP0009745_abnormal_behavioral_response1.26798453
44MP0005389_reproductive_system_phenotype1.26468417
45MP0001486_abnormal_startle_reflex1.23298566
46MP0002876_abnormal_thyroid_physiology1.22918402
47MP0005386_behavior/neurological_phenoty1.22782515
48MP0004924_abnormal_behavior1.22782515
49MP0008995_early_reproductive_senescence1.20211719
50MP0001919_abnormal_reproductive_system1.19406592
51MP0002098_abnormal_vibrissa_morphology1.15020961
52MP0005645_abnormal_hypothalamus_physiol1.14119518
53MP0001929_abnormal_gametogenesis1.11764959
54MP0000015_abnormal_ear_pigmentation1.11504633
55MP0003698_abnormal_male_reproductive1.11277032
56MP0002210_abnormal_sex_determination1.10552908
57MP0000427_abnormal_hair_cycle1.08119122
58MP0000778_abnormal_nervous_system1.06200958
59MP0000653_abnormal_sex_gland1.06084794
60MP0003119_abnormal_digestive_system1.05984022
61MP0000631_abnormal_neuroendocrine_gland1.05517956
62MP0002075_abnormal_coat/hair_pigmentati1.05477346
63MP0000462_abnormal_digestive_system1.05419562
64MP0002909_abnormal_adrenal_gland1.04185288
65MP0005084_abnormal_gallbladder_morpholo1.02533784
66MP0001145_abnormal_male_reproductive1.02091274
67MP0002837_dystrophic_cardiac_calcinosis0.98946703
68MP0001119_abnormal_female_reproductive0.98895540
69MP0003011_delayed_dark_adaptation0.97265654
70MP0005394_taste/olfaction_phenotype0.95809127
71MP0005499_abnormal_olfactory_system0.95809127
72MP0004142_abnormal_muscle_tone0.94826826
73MP0002064_seizures0.94663300
74MP0002233_abnormal_nose_morphology0.92255451
75MP0008873_increased_physiological_sensi0.91911879
76MP0003937_abnormal_limbs/digits/tail_de0.87869921
77MP0010307_abnormal_tumor_latency0.86393037
78MP0009046_muscle_twitch0.86127526
79MP0002184_abnormal_innervation0.85800300
80MP0008789_abnormal_olfactory_epithelium0.85607283
81MP0001764_abnormal_homeostasis0.85378965
82MP0000049_abnormal_middle_ear0.85081510
83MP0008875_abnormal_xenobiotic_pharmacok0.82112123
84MP0006276_abnormal_autonomic_nervous0.80600598
85MP0008932_abnormal_embryonic_tissue0.77585220
86MP0004215_abnormal_myocardial_fiber0.77276308
87MP0003111_abnormal_nucleus_morphology0.77195999
88MP0005395_other_phenotype0.76191026
89MP0001727_abnormal_embryo_implantation0.74154812
90MP0001529_abnormal_vocalization0.72838909
91MP0003567_abnormal_fetal_cardiomyocyte0.72705671
92MP0002272_abnormal_nervous_system0.71124655
93MP0002063_abnormal_learning/memory/cond0.69582358
94MP0005408_hypopigmentation0.67553100
95MP0002557_abnormal_social/conspecific_i0.64557919
96MP0001186_pigmentation_phenotype0.63981024
97MP0002396_abnormal_hematopoietic_system0.63271342
98MP0000613_abnormal_salivary_gland0.63041459
99MP0002067_abnormal_sensory_capabilities0.62801344
100MP0002111_abnormal_tail_morphology0.62736549

Predicted human phenotypes

RankGene SetZ-score
1Hyperventilation (HP:0002883)3.83489133
2Acute necrotizing encephalopathy (HP:0006965)3.54966224
3Colon cancer (HP:0003003)3.41900186
4Abnormality of the astrocytes (HP:0100707)3.35664398
5Astrocytoma (HP:0009592)3.35664398
6Ependymoma (HP:0002888)3.35082714
7Nephronophthisis (HP:0000090)3.34388926
8Progressive macrocephaly (HP:0004481)3.30920802
9Abnormal mitochondria in muscle tissue (HP:0008316)3.15706926
10Acute encephalopathy (HP:0006846)3.06021554
11Hypothermia (HP:0002045)3.05057883
12Mitochondrial inheritance (HP:0001427)2.86402621
13Renal cortical cysts (HP:0000803)2.84824722
14Absent speech (HP:0001344)2.84774880
15Focal seizures (HP:0007359)2.80313272
16Abnormality of the renal medulla (HP:0100957)2.78331475
17Focal motor seizures (HP:0011153)2.76883373
18Abnormality of the renal cortex (HP:0011035)2.69877881
19Glioma (HP:0009733)2.68804674
20Increased CSF lactate (HP:0002490)2.61683486
21Broad-based gait (HP:0002136)2.61122731
22Pancreatic cysts (HP:0001737)2.57921964
23Chromsome breakage (HP:0040012)2.55856580
24Methylmalonic acidemia (HP:0002912)2.54407271
25Stomach cancer (HP:0012126)2.53694833
26Drooling (HP:0002307)2.44633386
27Abnormality of midbrain morphology (HP:0002418)2.44511248
28Molar tooth sign on MRI (HP:0002419)2.44511248
29Abnormality of chromosome stability (HP:0003220)2.42707350
30Pancreatic fibrosis (HP:0100732)2.38443238
31Neonatal respiratory distress (HP:0002643)2.38043230
32Hypoproteinemia (HP:0003075)2.35220109
33Methylmalonic aciduria (HP:0012120)2.26979642
34Cerebral edema (HP:0002181)2.26659811
35Bony spicule pigmentary retinopathy (HP:0007737)2.25374098
36Excessive salivation (HP:0003781)2.22340538
37Adactyly (HP:0009776)2.20458476
38Aplasia/Hypoplasia of the uvula (HP:0010293)2.19836072
39Abnormality of the fetal cardiovascular system (HP:0010948)2.19571365
40Abnormal umbilical cord blood vessels (HP:0011403)2.19571365
41Single umbilical artery (HP:0001195)2.19571365
42Generalized hypopigmentation of hair (HP:0011358)2.18957138
43Meckel diverticulum (HP:0002245)2.16714681
44Oligodactyly (hands) (HP:0001180)2.14600570
45True hermaphroditism (HP:0010459)2.13825527
46Radial bowing (HP:0002986)2.10349023
47Neoplasm of the heart (HP:0100544)2.10062021
48Glycosuria (HP:0003076)2.09276470
49Abnormality of urine glucose concentration (HP:0011016)2.09276470
50Abnormality of the ileum (HP:0001549)2.07098399
51Dialeptic seizures (HP:0011146)2.07074249
52Protruding tongue (HP:0010808)2.06421509
53Fair hair (HP:0002286)2.04824151
54Volvulus (HP:0002580)2.04221769
55Abnormality of alanine metabolism (HP:0010916)2.03041363
56Hyperalaninemia (HP:0003348)2.03041363
57Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.03041363
58Papillary thyroid carcinoma (HP:0002895)2.02220736
59Thyroiditis (HP:0100646)2.02104858
60Abnormality of serum amino acid levels (HP:0003112)2.01445630
61Neoplasm of the peripheral nervous system (HP:0100007)2.01000085
62Unsteady gait (HP:0002317)1.98702951
63Hepatic necrosis (HP:0002605)1.97766104
64Abnormality of the columella (HP:0009929)1.97661797
65Redundant skin (HP:0001582)1.94738296
66Abnormality of aspartate family amino acid metabolism (HP:0010899)1.93737287
67Chronic hepatic failure (HP:0100626)1.92270218
68Lactic acidosis (HP:0003128)1.91997617
69Hypoplastic labia majora (HP:0000059)1.91511000
70Chromosomal breakage induced by crosslinking agents (HP:0003221)1.91025168
71Hepatocellular necrosis (HP:0001404)1.88282180
72Absent phalangeal crease (HP:0006109)1.84809250
73Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.84007068
74Abnormality of the preputium (HP:0100587)1.83830732
75Homocystinuria (HP:0002156)1.81672438
76Abnormality of homocysteine metabolism (HP:0010919)1.81672438
77Furrowed tongue (HP:0000221)1.80297325
78Increased serum lactate (HP:0002151)1.79151087
79Aplasia/Hypoplasia of the tibia (HP:0005772)1.78245052
80Occipital encephalocele (HP:0002085)1.76749303
81Hamartoma of the eye (HP:0010568)1.75758585
82Respiratory failure (HP:0002878)1.75563370
83Combined immunodeficiency (HP:0005387)1.74019096
84Abnormality of macular pigmentation (HP:0008002)1.72173120
85Clubbing of toes (HP:0100760)1.71966274
86Congenital stationary night blindness (HP:0007642)1.71770516
87Abnormal finger flexion creases (HP:0006143)1.71446523
88Abnormality of the labia majora (HP:0012881)1.70005880
89Bell-shaped thorax (HP:0001591)1.69395007
90Sloping forehead (HP:0000340)1.67987946
91Short 5th finger (HP:0009237)1.67813997
92Congenital hepatic fibrosis (HP:0002612)1.66155934
93Postaxial foot polydactyly (HP:0001830)1.65404168
94Lethargy (HP:0001254)1.65051612
95Albinism (HP:0001022)1.64976457
96Stomatitis (HP:0010280)1.64629556
97Abnormality of methionine metabolism (HP:0010901)1.64454673
98Tubulointerstitial nephritis (HP:0001970)1.63370505
99Hyperglycinuria (HP:0003108)1.63311165
100Narrow forehead (HP:0000341)1.63081508

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK133.36340396
2EPHA43.27967381
3CCNB13.25189598
4BRSK23.19496197
5TXK3.00530829
6MAP3K42.94999162
7FRK2.68799864
8CASK2.49501730
9CDK32.43327972
10STK162.31766253
11CLK12.00803787
12MAP2K71.97180703
13PIK3CG1.80977372
14MARK11.79767517
15GRK11.66262030
16BUB11.57367847
17PLK41.50998576
18AKT31.45949279
19NTRK31.45722865
20PDK21.40310104
21WNK41.36009535
22MAP4K21.35108820
23WNK31.34225940
24VRK11.31120752
25ZAK1.29407509
26SRPK11.28686959
27MST41.25291685
28ADRBK21.22271093
29SCYL21.20264153
30ERBB31.17602052
31UHMK11.16451273
32CAMKK21.16314142
33TTK1.15261967
34BRSK11.07080147
35DYRK21.06894642
36PLK11.05971294
37TNIK1.03082688
38OXSR10.99127591
39STK390.98810469
40BCR0.98511344
41GRK60.96482953
42CSNK1G30.93745375
43TEC0.90848073
44STK38L0.90169136
45NEK10.88808464
46FER0.88666154
47MKNK20.86083342
48PLK30.86046414
49CSNK1A1L0.83136176
50CSNK1G20.81078395
51MAP2K20.80803553
52ATR0.78106721
53PAK30.76801733
54PTK2B0.76685058
55NME10.74568600
56NUAK10.74126391
57BMPR1B0.73640123
58CSNK1G10.72945170
59ATM0.72070802
60IKBKB0.70965372
61KIT0.70118374
62INSRR0.69064859
63MAP2K10.68994038
64MAP3K60.66967611
65CDK80.65365936
66CDC70.63960737
67CAMK40.61455243
68ABL20.59313821
69IRAK10.58167914
70MINK10.56778444
71WEE10.56732738
72MAP3K70.55264466
73OBSCN0.53655188
74PBK0.52275677
75TLK10.51761658
76MKNK10.50240342
77TRIM280.50138659
78LYN0.48074720
79NTRK20.47489101
80MAP3K50.46293801
81TYK20.44347706
82PAK60.43955366
83SGK20.43896982
84PKN10.43678408
85CSNK2A10.41840419
86FES0.40177198
87EIF2AK10.40007557
88PIM10.39944913
89CSNK2A20.38231731
90MAP3K30.38220963
91PLK20.37909911
92EIF2AK30.37285187
93JAK30.37041844
94CSNK1D0.36320255
95YES10.35500298
96ROCK10.35123519
97IGF1R0.35035151
98RPS6KA40.33567680
99CHEK20.33480648
100PRKACA0.32444955

Predicted pathways (KEGG)

RankGene SetZ-score
1Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001304.47467276
2Non-homologous end-joining_Homo sapiens_hsa034503.83641490
3RNA polymerase_Homo sapiens_hsa030202.86753277
4Homologous recombination_Homo sapiens_hsa034402.83951143
5Oxidative phosphorylation_Homo sapiens_hsa001902.74578491
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.66652561
7Proteasome_Homo sapiens_hsa030502.46761932
8Fanconi anemia pathway_Homo sapiens_hsa034602.44291887
9Parkinsons disease_Homo sapiens_hsa050122.31795569
10Basal transcription factors_Homo sapiens_hsa030222.25290289
11Phototransduction_Homo sapiens_hsa047442.15609662
12DNA replication_Homo sapiens_hsa030301.92197343
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.86176206
14RNA degradation_Homo sapiens_hsa030181.78547495
15Mismatch repair_Homo sapiens_hsa034301.78328489
16Pyrimidine metabolism_Homo sapiens_hsa002401.76692323
17Nucleotide excision repair_Homo sapiens_hsa034201.74718974
18Propanoate metabolism_Homo sapiens_hsa006401.73548240
19Huntingtons disease_Homo sapiens_hsa050161.73501986
20Taste transduction_Homo sapiens_hsa047421.61320715
21Selenocompound metabolism_Homo sapiens_hsa004501.60848507
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.57698522
23Spliceosome_Homo sapiens_hsa030401.52402637
24Ether lipid metabolism_Homo sapiens_hsa005651.50818150
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.48258875
26Alzheimers disease_Homo sapiens_hsa050101.44917687
27Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.40668044
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.38688177
29Steroid biosynthesis_Homo sapiens_hsa001001.34400099
30Cyanoamino acid metabolism_Homo sapiens_hsa004601.32653636
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.30612315
32RNA transport_Homo sapiens_hsa030131.28588458
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28554109
34Protein export_Homo sapiens_hsa030601.25966072
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.23850744
36Primary bile acid biosynthesis_Homo sapiens_hsa001201.22503604
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.17182465
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.16831602
39Base excision repair_Homo sapiens_hsa034101.13829652
40One carbon pool by folate_Homo sapiens_hsa006701.10980995
41Linoleic acid metabolism_Homo sapiens_hsa005911.10900745
42Nicotine addiction_Homo sapiens_hsa050331.09952643
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.08518696
44Purine metabolism_Homo sapiens_hsa002301.08073776
45Fatty acid biosynthesis_Homo sapiens_hsa000611.05942524
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.03168232
47Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.98624271
48Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.98378859
49Pyruvate metabolism_Homo sapiens_hsa006200.88861468
50Ribosome_Homo sapiens_hsa030100.87635488
51Tryptophan metabolism_Homo sapiens_hsa003800.84356802
52Circadian entrainment_Homo sapiens_hsa047130.83958041
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83437793
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.80842998
55Nitrogen metabolism_Homo sapiens_hsa009100.80572218
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.79036211
57Olfactory transduction_Homo sapiens_hsa047400.78546583
58Metabolic pathways_Homo sapiens_hsa011000.71596766
59Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.69770969
60Systemic lupus erythematosus_Homo sapiens_hsa053220.62762311
61Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.57495102
62Lysine degradation_Homo sapiens_hsa003100.56962477
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.55647735
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55079127
65Sphingolipid metabolism_Homo sapiens_hsa006000.54326126
66Alcoholism_Homo sapiens_hsa050340.54153039
67Glutamatergic synapse_Homo sapiens_hsa047240.53628726
68Inositol phosphate metabolism_Homo sapiens_hsa005620.53552565
69Choline metabolism in cancer_Homo sapiens_hsa052310.52244687
70Cell cycle_Homo sapiens_hsa041100.51494454
71Fatty acid degradation_Homo sapiens_hsa000710.50844543
72Long-term depression_Homo sapiens_hsa047300.49363889
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.49071340
74Serotonergic synapse_Homo sapiens_hsa047260.48799738
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48426299
76Retinol metabolism_Homo sapiens_hsa008300.46004031
77Cardiac muscle contraction_Homo sapiens_hsa042600.44804409
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44255771
79beta-Alanine metabolism_Homo sapiens_hsa004100.40092476
80Butanoate metabolism_Homo sapiens_hsa006500.39252417
81p53 signaling pathway_Homo sapiens_hsa041150.37300042
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34812923
83Melanoma_Homo sapiens_hsa052180.34496682
84Epstein-Barr virus infection_Homo sapiens_hsa051690.33826672
85Fatty acid metabolism_Homo sapiens_hsa012120.33782994
86Sulfur metabolism_Homo sapiens_hsa009200.28522199
87Circadian rhythm_Homo sapiens_hsa047100.28392332
88Regulation of autophagy_Homo sapiens_hsa041400.27887071
89Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27399583
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27228518
91Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26363992
92Colorectal cancer_Homo sapiens_hsa052100.25005163
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24042984
94Dopaminergic synapse_Homo sapiens_hsa047280.22967347
95mRNA surveillance pathway_Homo sapiens_hsa030150.22152218
96Caffeine metabolism_Homo sapiens_hsa002320.20433739
97Glycerophospholipid metabolism_Homo sapiens_hsa005640.20183906
98Peroxisome_Homo sapiens_hsa041460.19849872
99Oocyte meiosis_Homo sapiens_hsa041140.18185587
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.16563490

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »