TINCR

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of water loss via skin (GO:0033561)9.91910371
2keratinocyte proliferation (GO:0043616)7.99019802
3sphingoid metabolic process (GO:0046519)7.38422772
4keratinization (GO:0031424)7.35308920
5multicellular organismal water homeostasis (GO:0050891)6.77295184
6keratinocyte differentiation (GO:0030216)6.60935855
7sphingosine metabolic process (GO:0006670)6.42027971
8diol metabolic process (GO:0034311)5.83242831
9regulation of phospholipase A2 activity (GO:0032429)5.80208858
10water homeostasis (GO:0030104)5.63039434
11hemidesmosome assembly (GO:0031581)5.54082101
12long-chain fatty acid biosynthetic process (GO:0042759)5.43577869
13fatty acid elongation (GO:0030497)5.36661620
14epidermal cell differentiation (GO:0009913)5.35127339
15interferon-gamma secretion (GO:0072643)5.30258882
16regulation of ruffle assembly (GO:1900027)5.16173294
17keratinocyte development (GO:0003334)5.09228180
18molting cycle (GO:0042303)5.02474056
19hair cycle (GO:0042633)5.02474056
20regulation of cell proliferation involved in kidney development (GO:1901722)4.92379388
21bundle of His cell to Purkinje myocyte communication (GO:0086069)4.89781544
22detection of bacterium (GO:0016045)4.88311317
23viral transcription (GO:0019083)4.87837390
24glucosamine-containing compound catabolic process (GO:1901072)4.86363251
25regulation of chemokine secretion (GO:0090196)4.68666003
26epidermis development (GO:0008544)4.65420783
27behavioral response to nicotine (GO:0035095)4.63173904
28positive regulation of interleukin-8 secretion (GO:2000484)4.59005020
29translational termination (GO:0006415)4.57793476
30cornea development in camera-type eye (GO:0061303)4.35141636
31peptide cross-linking (GO:0018149)4.32661350
32ribosomal small subunit biogenesis (GO:0042274)4.27835113
33positive regulation of chemokine secretion (GO:0090197)4.26589476
34detection of other organism (GO:0098543)4.09585122
35positive regulation of interleukin-4 production (GO:0032753)3.93677254
36intermediate filament organization (GO:0045109)3.91529518
37regulation of hypersensitivity (GO:0002883)3.76034893
38regulation of transforming growth factor beta1 production (GO:0032908)3.59722854
39negative regulation of interferon-gamma production (GO:0032689)3.59265216
40viral life cycle (GO:0019058)3.51195792
41long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.44980314
42SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.44537134
43cellular protein complex disassembly (GO:0043624)3.44141403
44translational elongation (GO:0006414)3.43398596
45response to pheromone (GO:0019236)3.42507115
46protein targeting to ER (GO:0045047)3.42252996
47skin morphogenesis (GO:0043589)3.42187204
48negative regulation of interleukin-2 production (GO:0032703)3.41895977
49cotranslational protein targeting to membrane (GO:0006613)3.38957724
50regulation of interleukin-8 secretion (GO:2000482)3.38404278
51cyclooxygenase pathway (GO:0019371)3.37476882
52negative regulation of kidney development (GO:0090185)3.36174137
53chemical homeostasis within a tissue (GO:0048875)3.35430665
54establishment of protein localization to endoplasmic reticulum (GO:0072599)3.33973074
55ectoderm development (GO:0007398)3.29299662
56piRNA metabolic process (GO:0034587)3.28514431
57cardiac right ventricle morphogenesis (GO:0003215)3.28210656
58gland morphogenesis (GO:0022612)3.27940691
59nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.27775644
60polarized epithelial cell differentiation (GO:0030859)3.25227334
61atrioventricular valve morphogenesis (GO:0003181)3.24766994
62retinal metabolic process (GO:0042574)3.22615883
63eyelid development in camera-type eye (GO:0061029)3.21579370
64G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.20046632
65maturation of SSU-rRNA (GO:0030490)3.20045902
66phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.19772917
67negative regulation of stress fiber assembly (GO:0051497)3.19658970
68protein localization to endoplasmic reticulum (GO:0070972)3.14544190
69phosphatidylinositol acyl-chain remodeling (GO:0036149)3.13550067
70phospholipid scrambling (GO:0017121)3.11966718
71negative regulation of keratinocyte proliferation (GO:0010839)3.05837437
72prostanoid biosynthetic process (GO:0046457)3.04838018
73prostaglandin biosynthetic process (GO:0001516)3.04838018
74detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.04309091
75establishment of tissue polarity (GO:0007164)3.03604525
76establishment of planar polarity (GO:0001736)3.03604525
77negative regulation of T cell mediated immunity (GO:0002710)3.00330124
78negative regulation of acute inflammatory response (GO:0002674)2.98468528
79positive regulation of glomerulus development (GO:0090193)2.98224416
80lateral sprouting from an epithelium (GO:0060601)2.97357719
81T-helper cell differentiation (GO:0042093)2.96250129
82CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.96250129
83phosphatidylserine acyl-chain remodeling (GO:0036150)2.92022921
84L-fucose catabolic process (GO:0042355)2.90992462
85fucose catabolic process (GO:0019317)2.90992462
86L-fucose metabolic process (GO:0042354)2.90992462
87regulation of somitogenesis (GO:0014807)2.90745584
88positive regulation of triglyceride biosynthetic process (GO:0010867)2.89431464
89sympathetic nervous system development (GO:0048485)2.86372094
90heart valve morphogenesis (GO:0003179)2.86178821
91linoleic acid metabolic process (GO:0043651)2.83180546
92regulation of glomerular filtration (GO:0003093)2.83135559
93protein complex disassembly (GO:0043241)2.81948578
94regulation of interleukin-4 production (GO:0032673)2.80600858
95regulation of triglyceride biosynthetic process (GO:0010866)2.80513824
96lipoxygenase pathway (GO:0019372)2.79499521
97ribosomal small subunit assembly (GO:0000028)2.79344831
98surfactant homeostasis (GO:0043129)2.77837871
99sphingolipid biosynthetic process (GO:0030148)2.76723977
100limb bud formation (GO:0060174)2.75972287
101DNA deamination (GO:0045006)2.74906886
102regulation of natural killer cell differentiation (GO:0032823)2.74322778
103glomerular visceral epithelial cell development (GO:0072015)2.73498884
104inflammatory response to antigenic stimulus (GO:0002437)2.73225085
105fatty-acyl-CoA metabolic process (GO:0035337)2.73079022
106detection of light stimulus involved in visual perception (GO:0050908)2.71555502
107detection of light stimulus involved in sensory perception (GO:0050962)2.71555502
108intestinal epithelial cell development (GO:0060576)2.71042553
109ubiquinone biosynthetic process (GO:0006744)2.71034792
110estrogen biosynthetic process (GO:0006703)2.70508813
111positive regulation of Cdc42 GTPase activity (GO:0043089)2.69775263
112regulation of acute inflammatory response to antigenic stimulus (GO:0002864)2.69007476
113regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.68337203
114DNA methylation involved in gamete generation (GO:0043046)2.67460555
115intermediate filament cytoskeleton organization (GO:0045104)2.67093921
116ceramide catabolic process (GO:0046514)2.65404641
117phosphatidylcholine acyl-chain remodeling (GO:0036151)2.65370677
118regulation of hippo signaling (GO:0035330)2.61973246
119intermediate filament-based process (GO:0045103)2.61759170
120nephron tubule morphogenesis (GO:0072078)2.61517894
121nephron epithelium morphogenesis (GO:0072088)2.61517894
122water-soluble vitamin biosynthetic process (GO:0042364)2.58431826
123cochlea development (GO:0090102)2.58195685
124auditory receptor cell stereocilium organization (GO:0060088)2.55566309
125ubiquinone metabolic process (GO:0006743)2.55498397
126regulation of keratinocyte proliferation (GO:0010837)2.46686507
127positive regulation of meiotic cell cycle (GO:0051446)2.45959448
128multicellular organism reproduction (GO:0032504)2.44820795
129regulation of mesoderm development (GO:2000380)2.43960870
130purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.43067560
1313-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.43067560
132reflex (GO:0060004)2.42740309
133epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.42543295
134phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.41948102
135tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.39694908
136RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.39694908
137regulation of nuclear cell cycle DNA replication (GO:0033262)2.38528819
138pattern specification involved in kidney development (GO:0061004)2.36516227
139regulation of action potential (GO:0098900)2.36146382
140mannosylation (GO:0097502)2.31752431
141rRNA modification (GO:0000154)2.31258583
142positive regulation of keratinocyte differentiation (GO:0045618)2.30739228
143respiratory chain complex IV assembly (GO:0008535)2.29771297
144nucleoside transmembrane transport (GO:1901642)2.29647240
145glycerophospholipid catabolic process (GO:0046475)2.29509569
146preassembly of GPI anchor in ER membrane (GO:0016254)2.28682592
147negative regulation of reactive oxygen species metabolic process (GO:2000378)2.25987108
148meiotic chromosome segregation (GO:0045132)2.23983586
149positive regulation of epidermal cell differentiation (GO:0045606)2.23907972
150platelet dense granule organization (GO:0060155)2.23460321
151establishment of protein localization to mitochondrial membrane (GO:0090151)2.23213376
152indolalkylamine metabolic process (GO:0006586)2.22832761
153regulation of heart rate by cardiac conduction (GO:0086091)2.22531253
154phospholipid catabolic process (GO:0009395)2.22456398
155basic amino acid transport (GO:0015802)2.21349913
156norepinephrine metabolic process (GO:0042415)2.20832881
157mitochondrial respiratory chain complex I assembly (GO:0032981)2.20307232
158NADH dehydrogenase complex assembly (GO:0010257)2.20307232
159mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.20307232
160GPI anchor metabolic process (GO:0006505)2.19596428
161adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.19505836
162somite development (GO:0061053)2.19436092
163sulfation (GO:0051923)2.18893452
164axoneme assembly (GO:0035082)2.18334006
165protein import into peroxisome matrix (GO:0016558)2.18263730
166desmosome organization (GO:0002934)13.0505851
167establishment of skin barrier (GO:0061436)10.4586128

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse6.45101727
2ZNF274_21170338_ChIP-Seq_K562_Hela3.49645929
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.46354671
4SOX9_24532713_ChIP-Seq_HFSC_Mouse2.91251467
5P63_26484246_Chip-Seq_KERATINOCYTES_Human2.88626744
6ESR1_21235772_ChIP-Seq_MCF-7_Human2.23878416
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.15569254
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.10294388
9TP63_17297297_ChIP-ChIP_HaCaT_Human14.4935670
10ESR2_21235772_ChIP-Seq_MCF-7_Human1.98839758
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.94082357
12ZNF217_24962896_ChIP-Seq_MCF-7_Human1.91359092
13FOXO3_23340844_ChIP-Seq_DLD1_Human1.91305042
14SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.90285831
15ZNF263_19887448_ChIP-Seq_K562_Human1.87025509
16SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.77744732
17SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.77744732
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.73810007
19HOXB7_26014856_ChIP-Seq_BT474_Human1.71165056
20ERA_21632823_ChIP-Seq_H3396_Human1.65338976
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65066085
22GATA3_21878914_ChIP-Seq_MCF-7_Human1.60020743
23CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.57972886
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.53906926
25FOXA1_27270436_Chip-Seq_PROSTATE_Human1.52133810
26FOXA1_25329375_ChIP-Seq_VCAP_Human1.52133810
27GABP_17652178_ChIP-ChIP_JURKAT_Human1.52031274
28NOTCH1_21737748_ChIP-Seq_TLL_Human1.50510119
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50170605
30ER_23166858_ChIP-Seq_MCF-7_Human1.49229987
31KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.47220841
32EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.46391272
33SOX2_20726797_ChIP-Seq_SW620_Human1.45520087
34TCF4_18268006_ChIP-ChIP_LS174T_Human1.44586300
35KLF5_25053715_ChIP-Seq_YYC3_Human1.43033486
36RUNX1_27514584_Chip-Seq_MCF-7_Human1.41563422
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41521378
38TP63_23658742_ChIP-Seq_EP156T_Human1.38226283
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.37162926
40E2F1_20622854_ChIP-Seq_HELA_Human1.35729295
41CJUN_26792858_Chip-Seq_BT549_Human1.31909321
42EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.31599856
43CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.31279713
44AR_21572438_ChIP-Seq_LNCaP_Human1.30703018
45AHR_22903824_ChIP-Seq_MCF-7_Human1.30217521
46CDX2_20551321_ChIP-Seq_CACO-2_Human1.28304521
47TAF2_19829295_ChIP-Seq_ESCs_Human1.27869115
48CTCF_27219007_Chip-Seq_Bcells_Human1.27361113
49P53_21459846_ChIP-Seq_SAOS-2_Human1.27148290
50TDRD3_21172665_ChIP-Seq_MCF-7_Human1.26909020
51JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.25403033
52TP53_22573176_ChIP-Seq_HFKS_Human1.21946783
53FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.21343086
54TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20792070
55TP63_22573176_ChIP-Seq_HFKS_Human1.19833548
56RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19362985
57TP53_20018659_ChIP-ChIP_R1E_Mouse1.19033891
58TP53_18474530_ChIP-ChIP_U2OS_Human1.18342924
59OCT4_20526341_ChIP-Seq_ESCs_Human1.18112749
60RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.16837672
61CTCF_20526341_ChIP-Seq_ESCs_Human1.16549535
62ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16489003
63AR_20517297_ChIP-Seq_VCAP_Human1.15961869
64ZFP57_27257070_Chip-Seq_ESCs_Mouse1.14122577
65REST_21632747_ChIP-Seq_MESCs_Mouse1.13825307
66NANOG_20526341_ChIP-Seq_ESCs_Human1.13421952
67NCOR_22424771_ChIP-Seq_293T_Human1.13156440
68STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.12950527
69SUZ12_27294783_Chip-Seq_ESCs_Mouse1.12890576
70RAC3_21632823_ChIP-Seq_H3396_Human1.12170138
71ESR1_20079471_ChIP-ChIP_T-47D_Human1.11986924
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10583604
73GBX2_23144817_ChIP-Seq_PC3_Human1.10080852
74MYC_19829295_ChIP-Seq_ESCs_Human1.09728099
75BCAT_22108803_ChIP-Seq_LS180_Human1.07977843
76RXR_22108803_ChIP-Seq_LS180_Human1.07943495
77ELF5_23300383_ChIP-Seq_T47D_Human1.07934699
78ETS1_20019798_ChIP-Seq_JURKAT_Human1.06953141
79FOXH1_21741376_ChIP-Seq_ESCs_Human1.06095611
80GATA4_25053715_ChIP-Seq_YYC3_Human1.05228949
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05132634
82EST1_17652178_ChIP-ChIP_JURKAT_Human1.04554979
83EZH2_27304074_Chip-Seq_ESCs_Mouse1.04526084
84BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03399063
85HIF1A_21447827_ChIP-Seq_MCF-7_Human1.02727214
86EED_16625203_ChIP-ChIP_MESCs_Mouse1.02428452
87SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.01416528
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.00707823
89AR_25329375_ChIP-Seq_VCAP_Human1.00700314
90SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.99499915
91GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.98553107
92KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98356745
93CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.98157465
94P68_20966046_ChIP-Seq_HELA_Human0.97726345
95KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.96887477
96ARNT_22903824_ChIP-Seq_MCF-7_Human0.96066909
97BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.95814336
98PHF8_20622854_ChIP-Seq_HELA_Human0.95086209
99PPAR_26484153_Chip-Seq_NCI-H1993_Human0.94436236
100EWS_26573619_Chip-Seq_HEK293_Human0.93957077
101MYC_18940864_ChIP-ChIP_HL60_Human0.93735458
102RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93469756
103SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.93294668
104HTT_18923047_ChIP-ChIP_STHdh_Human0.92289553
105CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.91844392
106ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.91838818
107CDX2_19796622_ChIP-Seq_MESCs_Mouse0.91440091
108RACK7_27058665_Chip-Seq_MCF-7_Human0.90718402
109FUS_26573619_Chip-Seq_HEK293_Human0.89476102
110SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.89309821
111REST_18959480_ChIP-ChIP_MESCs_Mouse0.89305772
112ETV2_25802403_ChIP-Seq_MESCs_Mouse0.89229866
113FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89097732
114RNF2_27304074_Chip-Seq_ESCs_Mouse0.88685450
115EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88387401
116SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87548267
117VDR_22108803_ChIP-Seq_LS180_Human0.87528277
118FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.86823864
119JARID2_20075857_ChIP-Seq_MESCs_Mouse0.86637381
120FOXH1_21741376_ChIP-Seq_EPCs_Human0.86433813
121SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.86070756
122RNF2_18974828_ChIP-Seq_MESCs_Mouse0.85981198
123EZH2_18974828_ChIP-Seq_MESCs_Mouse0.85981198
124NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.85797491
125IGF1R_20145208_ChIP-Seq_DFB_Human0.85704343
126GATA6_25053715_ChIP-Seq_YYC3_Human0.85261956
127FOXM1_26456572_ChIP-Seq_MCF-7_Human0.84591914
128ERG_20517297_ChIP-Seq_VCAP_Human0.84500822
129GATA3_24758297_ChIP-Seq_MCF-7_Human0.83745869
130SMC4_20622854_ChIP-Seq_HELA_Human0.83270301
131EZH2_27294783_Chip-Seq_ESCs_Mouse0.83237330
132UBF1/2_26484160_Chip-Seq_HMECs_Human0.83179883
133SMAD3_21741376_ChIP-Seq_HESCs_Human0.82926384
134NANOG_19829295_ChIP-Seq_ESCs_Human0.82125121
135JARID2_20064375_ChIP-Seq_MESCs_Mouse0.81722639
136SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.80584068
137STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.80156432
138CEBPB_22108803_ChIP-Seq_LS180_Human0.79921381
139PIAS1_25552417_ChIP-Seq_VCAP_Human0.79911307
140TCF4_22108803_ChIP-Seq_LS180_Human0.79488922
141FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.78475515
142GATA6_21074721_ChIP-Seq_CACO-2_Human0.78422513
143SOX2_27498859_Chip-Seq_STOMACH_Mouse0.78310898
144JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76566414
145ATF3_27146783_Chip-Seq_COLON_Human0.75194176
146RNF2_27304074_Chip-Seq_NSC_Mouse0.72755605
147DNAJC2_21179169_ChIP-ChIP_NT2_Human0.71505476
148SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.71154713
149FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.70871327
150SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.70599672
151CBX2_27304074_Chip-Seq_ESCs_Mouse0.70020836
152MTF2_20144788_ChIP-Seq_MESCs_Mouse0.69372294
153RARG_19884340_ChIP-ChIP_MEFs_Mouse0.68993597
154CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.66948028
155WT1_25993318_ChIP-Seq_PODOCYTE_Human0.66943918
156KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.65916404
157KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.65916404
158KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.65916404
159CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.65691394
160SA1_27219007_Chip-Seq_ERYTHROID_Human0.65479825
161TP53_16413492_ChIP-PET_HCT116_Human0.64472122
162P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.63526061
163ERG_21242973_ChIP-ChIP_JURKAT_Human0.63356330
164GATA2_21666600_ChIP-Seq_HMVEC_Human0.61487474
165WT1_19549856_ChIP-ChIP_CCG9911_Human0.60777074
166VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.59586398

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier7.90237613
2MP0003941_abnormal_skin_development5.44150821
3MP0010234_abnormal_vibrissa_follicle5.16595785
4MP0005501_abnormal_skin_physiology4.74210674
5MP0004381_abnormal_hair_follicle4.60547231
6MP0005275_abnormal_skin_tensile4.34233320
7MP0000383_abnormal_hair_follicle3.61540168
8MP0002254_reproductive_system_inflammat3.53606440
9MP0001216_abnormal_epidermal_layer3.50469975
10MP0002060_abnormal_skin_morphology3.49744508
11MP0010678_abnormal_skin_adnexa3.40768192
12MP0003453_abnormal_keratinocyte_physiol3.19140531
13MP0010771_integument_phenotype3.08831613
14MP0002098_abnormal_vibrissa_morphology2.94719005
15MP0002009_preneoplasia2.79062991
16MP0005451_abnormal_body_composition2.76417661
17MP0000647_abnormal_sebaceous_gland2.72953619
18MP0004947_skin_inflammation2.57731669
19MP0000377_abnormal_hair_follicle2.49066513
20MP0005174_abnormal_tail_pigmentation2.42975093
21MP0001346_abnormal_lacrimal_gland2.39752008
22MP0000467_abnormal_esophagus_morphology2.34898938
23MP0000579_abnormal_nail_morphology2.33252988
24MP0009780_abnormal_chondrocyte_physiolo2.32622039
25MP0000566_synostosis2.31774973
26MP0003878_abnormal_ear_physiology2.30099577
27MP0005377_hearing/vestibular/ear_phenot2.30099577
28MP0002653_abnormal_ependyma_morphology2.13609329
29MP0004885_abnormal_endolymph2.09009769
30MP0000427_abnormal_hair_cycle1.94160429
31MP0009379_abnormal_foot_pigmentation1.78628377
32MP0001188_hyperpigmentation1.77981113
33MP0001191_abnormal_skin_condition1.68831714
34MP0009931_abnormal_skin_appearance1.68388385
35MP0003566_abnormal_cell_adhesion1.61191064
36MP0000762_abnormal_tongue_morphology1.48885429
37MP0008872_abnormal_physiological_respon1.47912329
38MP0004185_abnormal_adipocyte_glucose1.45987198
39MP0001851_eye_inflammation1.42209056
40MP0001968_abnormal_touch/_nociception1.41969384
41MP0005551_abnormal_eye_electrophysiolog1.36487811
42MP0002876_abnormal_thyroid_physiology1.34992158
43MP0008875_abnormal_xenobiotic_pharmacok1.33661814
44MP0002938_white_spotting1.32912377
45MP0000367_abnormal_coat/_hair1.32811440
46MP0002837_dystrophic_cardiac_calcinosis1.26905229
47MP0001243_abnormal_dermal_layer1.25409671
48MP0009046_muscle_twitch1.21665213
49MP0001485_abnormal_pinna_reflex1.20810913
50MP0003787_abnormal_imprinting1.19990724
51MP0000015_abnormal_ear_pigmentation1.19489143
52MP0002736_abnormal_nociception_after1.19471773
53MP0001340_abnormal_eyelid_morphology1.15910708
54MP0003136_yellow_coat_color1.13380779
55MP0000516_abnormal_urinary_system1.07259669
56MP0005367_renal/urinary_system_phenotyp1.07259669
57MP0003011_delayed_dark_adaptation1.06953643
58MP0002909_abnormal_adrenal_gland1.06891779
59MP0008877_abnormal_DNA_methylation1.04608673
60MP0004133_heterotaxia1.04110381
61MP0004147_increased_porphyrin_level0.99394301
62MP0000569_abnormal_digit_pigmentation0.99140181
63MP0000631_abnormal_neuroendocrine_gland0.96570726
64MP0001502_abnormal_circadian_rhythm0.95752886
65MP0001984_abnormal_olfaction0.95046765
66MP0002638_abnormal_pupillary_reflex0.93289404
67MP0008004_abnormal_stomach_pH0.92444833
68MP0004782_abnormal_surfactant_physiolog0.91215156
69MP0006292_abnormal_olfactory_placode0.90885555
70MP0005646_abnormal_pituitary_gland0.90314653
71MP0003705_abnormal_hypodermis_morpholog0.89952705
72MP0004742_abnormal_vestibular_system0.89870573
73MP0010352_gastrointestinal_tract_polyps0.89423195
74MP0004142_abnormal_muscle_tone0.88021538
75MP0005076_abnormal_cell_differentiation0.87906398
76MP0001919_abnormal_reproductive_system0.87805437
77MP0002234_abnormal_pharynx_morphology0.86813561
78MP0009745_abnormal_behavioral_response0.85674398
79MP0004043_abnormal_pH_regulation0.83682768
80MP0002160_abnormal_reproductive_system0.83493655
81MP0005423_abnormal_somatic_nervous0.82665222
82MP0002877_abnormal_melanocyte_morpholog0.81537928
83MP0000462_abnormal_digestive_system0.81170788
84MP0002166_altered_tumor_susceptibility0.80099718
85MP0010030_abnormal_orbit_morphology0.79485548
86MP0002006_tumorigenesis0.79151502
87MP0000026_abnormal_inner_ear0.76623190
88MP0005408_hypopigmentation0.76496541
89MP0000627_abnormal_mammary_gland0.75500843
90MP0001986_abnormal_taste_sensitivity0.75065684
91MP0000372_irregular_coat_pigmentation0.72521174
92MP0002184_abnormal_innervation0.71322568
93MP0002277_abnormal_respiratory_mucosa0.69951034
94MP0002572_abnormal_emotion/affect_behav0.69459995
95MP0003436_decreased_susceptibility_to0.69392258
96MP0000465_gastrointestinal_hemorrhage0.68554741
97MP0005171_absent_coat_pigmentation0.68097159
98MP0003195_calcinosis0.68092833
99MP0002177_abnormal_outer_ear0.67516026
100MP0005389_reproductive_system_phenotype0.66985461
101MP0001756_abnormal_urination0.66121304
102MP0003880_abnormal_central_pattern0.66026474
103MP0002210_abnormal_sex_determination0.65771545
104MP0001324_abnormal_eye_pigmentation0.65720469
105MP0005023_abnormal_wound_healing0.64590888
106MP0005253_abnormal_eye_physiology0.64257325
107MP0002557_abnormal_social/conspecific_i0.64091500
108MP0003763_abnormal_thymus_physiology0.63516671
109MP0002272_abnormal_nervous_system0.62034475
110MP0002102_abnormal_ear_morphology0.61001327
111MP0003938_abnormal_ear_development0.60886685
112MP0001944_abnormal_pancreas_morphology0.60882931
113MP0001784_abnormal_fluid_regulation0.58426892
114MP0002751_abnormal_autonomic_nervous0.57562392
115MP0000371_diluted_coat_color0.57446461
116MP0002233_abnormal_nose_morphology0.56181445
117MP0000470_abnormal_stomach_morphology0.56035358
118MP0003191_abnormal_cellular_cholesterol0.53509595
119MP0009384_cardiac_valve_regurgitation0.52186646
120MP0009053_abnormal_anal_canal0.51284836
121MP0002249_abnormal_larynx_morphology0.50593724
122MP0004272_abnormal_basement_membrane0.50231799
123MP0000538_abnormal_urinary_bladder0.47653201
124MP0004019_abnormal_vitamin_homeostasis0.47616981
125MP0002132_abnormal_respiratory_system0.47579453
126MP0005075_abnormal_melanosome_morpholog0.47478488
127MP0002090_abnormal_vision0.47267956
128MP0002148_abnormal_hypersensitivity_rea0.47095345
129MP0003950_abnormal_plasma_membrane0.46514639
130MP0005248_abnormal_Harderian_gland0.45024282
131MP0005409_darkened_coat_color0.45012732
132MP0000613_abnormal_salivary_gland0.43205425
133MP0002282_abnormal_trachea_morphology0.43107329
134MP0003755_abnormal_palate_morphology0.41808678
135MP0008789_abnormal_olfactory_epithelium0.41578005
136MP0003638_abnormal_response/metabolism_0.40651826
137MP0001873_stomach_inflammation0.40365243
138MP0002095_abnormal_skin_pigmentation0.39895038
139MP0004264_abnormal_extraembryonic_tissu0.39768065
140MP0000537_abnormal_urethra_morphology0.39687733
141MP0009250_abnormal_appendicular_skeleto0.38329281
142MP0003315_abnormal_perineum_morphology0.38281556
143MP0010155_abnormal_intestine_physiology0.37159849
144MP0003385_abnormal_body_wall0.34680865
145MP0001849_ear_inflammation0.33853894
146MP0005623_abnormal_meninges_morphology0.33576303
147MP0003936_abnormal_reproductive_system0.33350504
148MP0000432_abnormal_head_morphology0.32431140
149MP0001177_atelectasis0.32309689
150MP0006072_abnormal_retinal_apoptosis0.31932464
151MP0005647_abnormal_sex_gland0.31688362
152MP0005508_abnormal_skeleton_morphology0.31575847
153MP0005499_abnormal_olfactory_system0.29860212
154MP0005394_taste/olfaction_phenotype0.29860212
155MP0000685_abnormal_immune_system0.29646294
156MP0002111_abnormal_tail_morphology0.27715345
157MP0003045_fibrosis0.26741916

Predicted human phenotypes

RankGene SetZ-score
1Congenital nonbullous ichthyosiform erythroderma (HP:0007479)7.25287381
2Congenital ichthyosiform erythroderma (HP:0007431)7.06468498
3Hypotrichosis (HP:0001006)6.90198339
4Lip pit (HP:0100267)6.50417129
5Parakeratosis (HP:0001036)6.20507645
6Woolly hair (HP:0002224)5.68218936
7Onycholysis (HP:0001806)5.56439910
8Increased IgE level (HP:0003212)5.54376090
9Right ventricular cardiomyopathy (HP:0011663)5.28301264
10Plantar hyperkeratosis (HP:0007556)5.22107569
11Fragile nails (HP:0001808)4.99012536
12Erythroderma (HP:0001019)4.95585781
13Erythema (HP:0010783)4.90772746
14Palmoplantar hyperkeratosis (HP:0000972)4.68285705
15Popliteal pterygium (HP:0009756)4.38907532
16Palmar hyperkeratosis (HP:0010765)4.35209821
17Abnormality of secondary sexual hair (HP:0009888)4.17828439
18Abnormality of the axillary hair (HP:0100134)4.17828439
19Hypohidrosis (HP:0000966)3.96108474
20Ectropion (HP:0000656)3.95556353
21Abnormality of nail color (HP:0100643)3.91770131
22Milia (HP:0001056)3.80067193
23Corneal erosion (HP:0200020)3.75988576
24Curly hair (HP:0002212)3.73842505
25Pili torti (HP:0003777)3.71683723
26Hyporeflexia of lower limbs (HP:0002600)3.52447456
27Abnormal blistering of the skin (HP:0008066)3.44866789
28Abnormality of cells of the erythroid lineage (HP:0012130)3.25713566
29Amelogenesis imperfecta (HP:0000705)3.16709198
30Sparse scalp hair (HP:0002209)3.11323726
31Pruritus (HP:0000989)3.06812375
32Gangrene (HP:0100758)3.06288982
33Type II lissencephaly (HP:0007260)3.00941254
34Conjunctival hamartoma (HP:0100780)2.94870387
35Nail dystrophy (HP:0008404)2.89992863
36Sparse eyelashes (HP:0000653)2.86791230
37Hypoplastic labia majora (HP:0000059)2.85401925
38Molar tooth sign on MRI (HP:0002419)2.84583819
39Abnormality of midbrain morphology (HP:0002418)2.84583819
40Acanthosis nigricans (HP:0000956)2.84421784
41Abnormal number of erythroid precursors (HP:0012131)2.81471897
42Ventricular tachycardia (HP:0004756)2.81374745
43Congenital stationary night blindness (HP:0007642)2.78597748
44Distal lower limb muscle weakness (HP:0009053)2.77558374
45Concave nail (HP:0001598)2.76466107
46Anhidrosis (HP:0000970)2.74266725
47Pancreatic cysts (HP:0001737)2.73738926
48Abnormal hemoglobin (HP:0011902)2.70786839
49Pterygium (HP:0001059)2.69372007
50Aplasia cutis congenita (HP:0001057)2.68787453
51Advanced eruption of teeth (HP:0006288)2.68436206
52Thick nail (HP:0001805)2.67753179
53Oligodontia (HP:0000677)2.63626638
54Natal tooth (HP:0000695)2.62924941
55True hermaphroditism (HP:0010459)2.61525899
56Reticulocytopenia (HP:0001896)2.60177432
57Severe Myopia (HP:0011003)2.59626112
58Palmoplantar keratoderma (HP:0000982)2.58649106
59Furrowed tongue (HP:0000221)2.57308995
60Abnormality of the labia majora (HP:0012881)2.56773504
61Abnormality of the salivary glands (HP:0010286)2.49917561
62Duplicated collecting system (HP:0000081)2.48449394
63Septate vagina (HP:0001153)2.46164336
64Congenital, generalized hypertrichosis (HP:0004540)2.38913253
65Abnormality of the renal collecting system (HP:0004742)2.38390408
66Pancreatic fibrosis (HP:0100732)2.36321976
67Abnormal hair laboratory examination (HP:0003328)2.34587766
68Cerebellar dysplasia (HP:0007033)2.32301352
69Areflexia of lower limbs (HP:0002522)2.32244929
70Tubular atrophy (HP:0000092)2.26262043
71Dry skin (HP:0000958)2.24751850
72Pendular nystagmus (HP:0012043)2.24294494
73Large for gestational age (HP:0001520)2.23879286
74Slow-growing hair (HP:0002217)2.22790651
75Abnormality of hair growth rate (HP:0011363)2.22790651
76Stenosis of the external auditory canal (HP:0000402)2.21736552
77Abnormality of the gastric mucosa (HP:0004295)2.20609541
78Macrocytic anemia (HP:0001972)2.17073698
79Brittle hair (HP:0002299)2.16694327
80Nephronophthisis (HP:0000090)2.16495351
81Aplasia/hypoplasia of the uterus (HP:0008684)2.16056347
82Skin pits (HP:0100276)2.15572199
83Abnormal rod and cone electroretinograms (HP:0008323)2.15149642
84Ridged nail (HP:0001807)2.15078193
85Atrophic scars (HP:0001075)2.11065295
86Dehydration (HP:0001944)2.09835653
87Aplasia of the phalanges of the hand (HP:0009802)2.09624897
88Aplasia involving bones of the extremities (HP:0009825)2.09624897
89Aplasia involving bones of the upper limbs (HP:0009823)2.09624897
90Abnormality of alanine metabolism (HP:0010916)2.09518901
91Hyperalaninemia (HP:0003348)2.09518901
92Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.09518901
93Absent eyebrow (HP:0002223)2.05802943
94Hypodontia (HP:0000668)2.04634486
95Birth length less than 3rd percentile (HP:0003561)2.04484485
96Hypoplasia of dental enamel (HP:0006297)2.04470325
97Attenuation of retinal blood vessels (HP:0007843)2.04231014
98Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.00373661
99Conical tooth (HP:0000698)1.98589257
100Polydipsia (HP:0001959)1.95903689
101Abnormal drinking behavior (HP:0030082)1.95903689
102Pustule (HP:0200039)1.94618189
103Labial hypoplasia (HP:0000066)1.93950281
104Abnormality of the renal medulla (HP:0100957)1.93004229
105Patellar aplasia (HP:0006443)1.90201030
106Abnormality of permanent molar morphology (HP:0011071)1.88267478
107Abnormality of the dental root (HP:0006486)1.88267478
108Taurodontia (HP:0000679)1.88267478
109Hypoplasia of the iris (HP:0007676)1.88254330
110Aplasia/Hypoplasia of the patella (HP:0006498)1.86783977
111Malignant hyperthermia (HP:0002047)1.85987870
112Rib fusion (HP:0000902)1.85969644
113Pallor (HP:0000980)1.85847970
114Hypoparathyroidism (HP:0000829)1.85586991
115Blepharitis (HP:0000498)1.82979708
116Cystic liver disease (HP:0006706)1.82705803
117Absent thumb (HP:0009777)1.81942025
118Absent rod-and cone-mediated responses on ERG (HP:0007688)1.80945123
119Ventricular fibrillation (HP:0001663)1.80694975
120Breast hypoplasia (HP:0003187)1.79876746
121Inability to walk (HP:0002540)1.79627398
122Alopecia of scalp (HP:0002293)1.78938709
123Retinal dysplasia (HP:0007973)1.78216878
124Down-sloping shoulders (HP:0200021)1.77186497
125Aplasia/Hypoplasia of the spleen (HP:0010451)1.75658445
126Decreased circulating renin level (HP:0003351)1.75497525
127Abnormality of the renal cortex (HP:0011035)1.74845981
128Upper limb muscle weakness (HP:0003484)1.74027368
129Lack of skin elasticity (HP:0100679)1.73911043
130Corneal dystrophy (HP:0001131)1.73838841
131Hypoplastic female external genitalia (HP:0012815)1.73685523
132Non-midline cleft lip (HP:0100335)1.73630695
133Abnormality of the pons (HP:0007361)1.72750588
134Sclerocornea (HP:0000647)1.72611918
135Asplenia (HP:0001746)1.70637165
136Hypoplasia of the radius (HP:0002984)1.70408993
137Hamartoma of the eye (HP:0010568)1.70108605
138Trismus (HP:0000211)1.68993905
139Fasciculations (HP:0002380)1.67688977
140Hypoplasia of the pons (HP:0012110)1.66985259
141Abnormality of the dental pulp (HP:0006479)1.66674466
142Nasolacrimal duct obstruction (HP:0000579)1.66593148
143Abnormality of molar (HP:0011077)1.66525395
144Abnormality of molar morphology (HP:0011070)1.66525395
145Increased corneal curvature (HP:0100692)1.65860350
146Keratoconus (HP:0000563)1.65860350
147Esophageal atresia (HP:0002032)1.65776122
148Hypoplasia of the uterus (HP:0000013)1.65023904
149Bilateral microphthalmos (HP:0007633)1.64965711
150Bifid scrotum (HP:0000048)1.64809608
151Fatigable weakness (HP:0003473)1.63440751
152Abnormality of the neuromuscular junction (HP:0003398)1.63440751
153Abnormality of the distal phalanges of the toes (HP:0010182)1.63313212
154Male pseudohermaphroditism (HP:0000037)1.63052221
155Hyperventilation (HP:0002883)1.61900630
156Fair hair (HP:0002286)1.61819416
157Hypergammaglobulinemia (HP:0010702)1.59667008
158Anophthalmia (HP:0000528)1.58992450
159Split foot (HP:0001839)1.58778878
160Abnormality of the lacrimal duct (HP:0011481)1.57602222

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST44.98367136
2MST1R4.65794591
3MAP3K34.03099831
4MAPKAPK33.64882815
5MAP3K23.24799249
6WNK43.03806867
7FER2.98574403
8PINK12.62776706
9ADRBK22.62463110
10RPS6KB22.45747030
11NME12.39970006
12STK38L2.18671729
13MAP3K142.18260031
14PIM22.15354931
15LRRK22.07858059
16TLK12.01764546
17MUSK1.92900814
18INSRR1.92893962
19MAPKAPK51.92248014
20ZAK1.87397934
21GRK11.84570485
22TRPM71.83675878
23STK101.81470823
24TGFBR11.78300202
25EPHA31.76274103
26ACVR1B1.71727533
27EPHB21.69320646
28MAPK151.54674796
29ERBB31.53365957
30BCR1.50822966
31MET1.46722172
32MAP3K91.45421862
33ERN11.44107679
34BMPR21.42367255
35TRIM281.40066800
36EPHA21.37713807
37STK31.37596663
38ITK1.37137652
39WNK31.34593284
40DYRK1B1.30776720
41DAPK21.25501722
42CASK1.22193406
43PTK61.21643866
44MAPK131.20459638
45STK241.18769722
46IRAK31.18309718
47NUAK11.15531647
48ADRBK11.11607327
49FGFR21.10677308
50TAOK21.08540180
51IKBKB1.07529282
52NTRK31.06076570
53PHKG21.05964317
54PHKG11.05964317
55IKBKE1.04699605
56FGFR41.02806863
57EPHB11.02671519
58PIK3CA1.01575699
59MAPKAPK21.01490851
60DYRK20.99777347
61WEE10.98848747
62STK390.96912600
63LATS10.96738732
64PRPF4B0.94066753
65MAP2K60.92946810
66CDK190.90378797
67NEK20.90013177
68TYK20.88357963
69EIF2AK20.87467747
70BMPR1B0.86767223
71RIPK40.86187514
72TGFBR20.84801316
73PNCK0.83490962
74MAP3K10.82589078
75TXK0.82253045
76PRKCG0.80131135
77MAP4K20.78155220
78GRK70.77628134
79DMPK0.76908534
80NTRK20.74953818
81HIPK20.74452660
82TNK20.72817525
83YES10.72328697
84CSNK1G10.72181220
85MAP2K20.71792088
86TYRO30.71445240
87PKN10.69363923
88EPHA40.69059186
89FGFR30.67407733
90MAP3K70.64324545
91PRKD10.62479721
92PAK30.62356660
93PIK3CG0.60701135
94SIK10.59795574
95PTK20.59377411
96CHUK0.58797009
97WNK10.58192900
98CSNK1G30.57412655
99TESK10.56740616
100FGFR10.54025974
101CDK30.53938599
102TAOK10.53790150
103CDK60.53124251
104RPS6KB10.52894288
105MAP3K110.51480025
106PRKCI0.50275495
107MAP3K60.49051800
108CSNK1A10.49014215
109MARK20.48877400
110EEF2K0.48226698
111CSNK1G20.47553736
112ROCK20.47044116
113OXSR10.45529376
114PRKCE0.44738130
115NEK60.44516441
116CSNK1A1L0.44367721
117CAMK10.44083484
118BLK0.43987710
119PBK0.43353983
120TAF10.43148874
121BTK0.43148449
122PLK10.42818886
123ERBB20.41967730
124RPS6KA10.41621930
125MAP2K70.41389121
126CAMK2D0.41305834
127CHEK20.40726027
128BMX0.40438632
129PRKD20.40263545
130GRK50.39738178
131LATS20.39507207
132CSNK1E0.39037996
133PRKCZ0.38192433
134MINK10.38022446
135MAP2K10.37335270
136MATK0.36733622
137RPS6KA50.36324190
138CSNK1D0.35142250
139ABL10.35134306
140JAK10.34685729
141PRKAA10.33645441
142LMTK20.33629990
143TTN0.33150835
144MAPK70.32337957
145STK380.32038556
146SGK4940.31648733
147SGK2230.31648733
148NME20.31121879
149RIPK10.30540148
150PRKACA0.30395315
151NLK0.30118809
152PRKCA0.29615717
153STK110.29570373
154GSK3A0.29472057
155PDGFRB0.28001222
156AKT20.27930552
157FRK0.27551770
158MAPK30.27532065
159CAMK2A0.26034306

Predicted pathways (KEGG)

RankGene SetZ-score
1Sphingolipid metabolism_Homo sapiens_hsa006003.93278867
2Ribosome_Homo sapiens_hsa030103.74681482
3Cyanoamino acid metabolism_Homo sapiens_hsa004603.60259277
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.98598350
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.78672091
6Fatty acid elongation_Homo sapiens_hsa000622.69054052
7Linoleic acid metabolism_Homo sapiens_hsa005912.57600854
8Oxidative phosphorylation_Homo sapiens_hsa001902.48687657
9Nitrogen metabolism_Homo sapiens_hsa009102.45818394
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.45035133
11Arachidonic acid metabolism_Homo sapiens_hsa005902.36022707
12Selenocompound metabolism_Homo sapiens_hsa004502.24531406
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.08614511
14Folate biosynthesis_Homo sapiens_hsa007901.90052801
15Maturity onset diabetes of the young_Homo sapiens_hsa049501.87795536
16Retinol metabolism_Homo sapiens_hsa008301.82226923
17Histidine metabolism_Homo sapiens_hsa003401.81015238
18Ether lipid metabolism_Homo sapiens_hsa005651.78089093
19Phenylalanine metabolism_Homo sapiens_hsa003601.68579323
20Sulfur relay system_Homo sapiens_hsa041221.67147982
21Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.63549644
22Regulation of autophagy_Homo sapiens_hsa041401.60649083
23Axon guidance_Homo sapiens_hsa043601.54205680
24Basal transcription factors_Homo sapiens_hsa030221.54011629
25Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.53957286
26Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.53270039
27Parkinsons disease_Homo sapiens_hsa050121.50932952
28Basal cell carcinoma_Homo sapiens_hsa052171.47956777
29Butanoate metabolism_Homo sapiens_hsa006501.45770010
30Phototransduction_Homo sapiens_hsa047441.44783672
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.43117399
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.39845699
33Tight junction_Homo sapiens_hsa045301.32608937
34Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.32515322
35VEGF signaling pathway_Homo sapiens_hsa043701.32373137
36Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.29119957
37Adherens junction_Homo sapiens_hsa045201.28600941
38Sphingolipid signaling pathway_Homo sapiens_hsa040711.27986061
39Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.27972737
40Chemical carcinogenesis_Homo sapiens_hsa052041.27679352
41Tryptophan metabolism_Homo sapiens_hsa003801.23527249
42RNA polymerase_Homo sapiens_hsa030201.19135040
43Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.16211998
44Nicotine addiction_Homo sapiens_hsa050331.15380629
45Fanconi anemia pathway_Homo sapiens_hsa034601.15091356
46Cardiac muscle contraction_Homo sapiens_hsa042601.11768713
47Fatty acid biosynthesis_Homo sapiens_hsa000611.11667007
48Alzheimers disease_Homo sapiens_hsa050101.10809053
49Homologous recombination_Homo sapiens_hsa034401.10681482
50Huntingtons disease_Homo sapiens_hsa050161.10567400
51Hippo signaling pathway_Homo sapiens_hsa043901.08180774
52Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.07951136
53Peroxisome_Homo sapiens_hsa041461.05020724
54p53 signaling pathway_Homo sapiens_hsa041151.04295550
55Pancreatic secretion_Homo sapiens_hsa049721.03407175
56Serotonergic synapse_Homo sapiens_hsa047261.03360587
57Renin secretion_Homo sapiens_hsa049241.02775210
58Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.99950611
59Leukocyte transendothelial migration_Homo sapiens_hsa046700.99412031
60Mineral absorption_Homo sapiens_hsa049780.98708039
61ECM-receptor interaction_Homo sapiens_hsa045120.96409959
62GnRH signaling pathway_Homo sapiens_hsa049120.95152061
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.95151539
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93994866
65Long-term depression_Homo sapiens_hsa047300.93961601
66Olfactory transduction_Homo sapiens_hsa047400.93242583
67Caffeine metabolism_Homo sapiens_hsa002320.93065428
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92785938
69Dorso-ventral axis formation_Homo sapiens_hsa043200.91707876
70MicroRNAs in cancer_Homo sapiens_hsa052060.90449597
71ABC transporters_Homo sapiens_hsa020100.90297714
72Insulin secretion_Homo sapiens_hsa049110.90257024
73Proteoglycans in cancer_Homo sapiens_hsa052050.90134040
74Proteasome_Homo sapiens_hsa030500.89469630
75Hedgehog signaling pathway_Homo sapiens_hsa043400.86723889
76Vitamin digestion and absorption_Homo sapiens_hsa049770.85149258
77Protein export_Homo sapiens_hsa030600.84768069
78Toxoplasmosis_Homo sapiens_hsa051450.84550887
79Ras signaling pathway_Homo sapiens_hsa040140.83175643
80RNA degradation_Homo sapiens_hsa030180.81425148
81Sulfur metabolism_Homo sapiens_hsa009200.81142682
82Hepatitis C_Homo sapiens_hsa051600.80232147
83ErbB signaling pathway_Homo sapiens_hsa040120.79606525
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.77286342
85Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75810232
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.75247658
87Tyrosine metabolism_Homo sapiens_hsa003500.74567785
88Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.74362543
89Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.74099767
90Glutathione metabolism_Homo sapiens_hsa004800.73966967
91Metabolic pathways_Homo sapiens_hsa011000.73815081
92Melanogenesis_Homo sapiens_hsa049160.73806708
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.73340236
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72701312
95NOD-like receptor signaling pathway_Homo sapiens_hsa046210.72004622
96Bladder cancer_Homo sapiens_hsa052190.70672147
97One carbon pool by folate_Homo sapiens_hsa006700.68182728
98Circadian entrainment_Homo sapiens_hsa047130.68104375
99Wnt signaling pathway_Homo sapiens_hsa043100.67344410
100T cell receptor signaling pathway_Homo sapiens_hsa046600.67137798
101Circadian rhythm_Homo sapiens_hsa047100.66400655
102Gastric acid secretion_Homo sapiens_hsa049710.65302629
103Rap1 signaling pathway_Homo sapiens_hsa040150.65126503
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63898286
105TGF-beta signaling pathway_Homo sapiens_hsa043500.63332659
106Glycerolipid metabolism_Homo sapiens_hsa005610.62184910
107Platelet activation_Homo sapiens_hsa046110.61099321
108Taste transduction_Homo sapiens_hsa047420.61092846
109Endometrial cancer_Homo sapiens_hsa052130.60146311
110Amoebiasis_Homo sapiens_hsa051460.59296012
111Choline metabolism in cancer_Homo sapiens_hsa052310.58444208
112Fat digestion and absorption_Homo sapiens_hsa049750.57997798
113Synaptic vesicle cycle_Homo sapiens_hsa047210.57977224
114Ovarian steroidogenesis_Homo sapiens_hsa049130.56206690
115MAPK signaling pathway_Homo sapiens_hsa040100.55879816
116Small cell lung cancer_Homo sapiens_hsa052220.55679054
117Collecting duct acid secretion_Homo sapiens_hsa049660.55563853
118Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.54732817
119Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.53401211
120Morphine addiction_Homo sapiens_hsa050320.53043876
121Acute myeloid leukemia_Homo sapiens_hsa052210.51471389
122Pertussis_Homo sapiens_hsa051330.49740294
123Vascular smooth muscle contraction_Homo sapiens_hsa042700.49163509
124Melanoma_Homo sapiens_hsa052180.47928929
125Glycerophospholipid metabolism_Homo sapiens_hsa005640.47879838
126Propanoate metabolism_Homo sapiens_hsa006400.47701078
127Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47405703
128Salivary secretion_Homo sapiens_hsa049700.46478803
129Dopaminergic synapse_Homo sapiens_hsa047280.46388686
130Steroid biosynthesis_Homo sapiens_hsa001000.45527382
131Calcium signaling pathway_Homo sapiens_hsa040200.44821113
132Prostate cancer_Homo sapiens_hsa052150.44663077
133Pyrimidine metabolism_Homo sapiens_hsa002400.44499952
134Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44404572
135Osteoclast differentiation_Homo sapiens_hsa043800.43979286
136Glutamatergic synapse_Homo sapiens_hsa047240.43696256
137Pathways in cancer_Homo sapiens_hsa052000.43272924
138Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.43258807
139Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.42886379
140Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42571930
141Hematopoietic cell lineage_Homo sapiens_hsa046400.41900180
142Aldosterone synthesis and secretion_Homo sapiens_hsa049250.41516662
143Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40655379
144Inositol phosphate metabolism_Homo sapiens_hsa005620.40061825
145beta-Alanine metabolism_Homo sapiens_hsa004100.39409985
146Oxytocin signaling pathway_Homo sapiens_hsa049210.38292424
147Endocytosis_Homo sapiens_hsa041440.38217467
148Arginine and proline metabolism_Homo sapiens_hsa003300.38126088
149Leishmaniasis_Homo sapiens_hsa051400.36759936
150Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.36313284
151Primary immunodeficiency_Homo sapiens_hsa053400.36002717
152Protein digestion and absorption_Homo sapiens_hsa049740.35805225
153Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33702748
154GABAergic synapse_Homo sapiens_hsa047270.30830710
155Amphetamine addiction_Homo sapiens_hsa050310.27756149

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