Rank | Gene Set | Z-score |
---|---|---|
1 | axonemal dynein complex assembly (GO:0070286) | 9.38870786 |
2 | cilium or flagellum-dependent cell motility (GO:0001539) | 7.18657467 |
3 | motile cilium assembly (GO:0044458) | 6.93596361 |
4 | cilium movement (GO:0003341) | 6.03794333 |
5 | vitamin transmembrane transport (GO:0035461) | 5.91580804 |
6 | intestinal absorption (GO:0050892) | 5.60627873 |
7 | intestinal cholesterol absorption (GO:0030299) | 5.51416035 |
8 | sulfur amino acid catabolic process (GO:0000098) | 5.45563034 |
9 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.16841411 |
10 | epithelial cilium movement (GO:0003351) | 4.80950564 |
11 | bile acid and bile salt transport (GO:0015721) | 4.77349147 |
12 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.72272638 |
13 | intestinal epithelial cell development (GO:0060576) | 4.53381270 |
14 | transcytosis (GO:0045056) | 4.37729685 |
15 | regulation of cholesterol homeostasis (GO:2000188) | 4.35107229 |
16 | multicellular organismal water homeostasis (GO:0050891) | 4.34086010 |
17 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 4.29397012 |
18 | homocysteine metabolic process (GO:0050667) | 4.25887001 |
19 | cysteine metabolic process (GO:0006534) | 4.16272597 |
20 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 4.13191010 |
21 | L-phenylalanine metabolic process (GO:0006558) | 4.12562362 |
22 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 4.12562362 |
23 | epoxygenase P450 pathway (GO:0019373) | 4.12435665 |
24 | oligosaccharide biosynthetic process (GO:0009312) | 4.11198631 |
25 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 4.10039087 |
26 | sperm capacitation (GO:0048240) | 4.09760460 |
27 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.08784519 |
28 | urea cycle (GO:0000050) | 4.07381321 |
29 | urea metabolic process (GO:0019627) | 4.07381321 |
30 | negative regulation of cholesterol transport (GO:0032375) | 4.01610266 |
31 | negative regulation of sterol transport (GO:0032372) | 4.01610266 |
32 | interferon-gamma secretion (GO:0072643) | 4.00517642 |
33 | establishment of apical/basal cell polarity (GO:0035089) | 4.00394299 |
34 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 3.98147079 |
35 | regulation of triglyceride catabolic process (GO:0010896) | 3.96003335 |
36 | regulation of bile acid biosynthetic process (GO:0070857) | 3.94942304 |
37 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.89851295 |
38 | L-phenylalanine catabolic process (GO:0006559) | 3.89851295 |
39 | maintenance of gastrointestinal epithelium (GO:0030277) | 3.85736715 |
40 | drug catabolic process (GO:0042737) | 3.84849631 |
41 | NADH metabolic process (GO:0006734) | 3.84389274 |
42 | ethanol metabolic process (GO:0006067) | 3.84017228 |
43 | phospholipid efflux (GO:0033700) | 3.82437947 |
44 | lung epithelium development (GO:0060428) | 3.81476206 |
45 | flavonoid metabolic process (GO:0009812) | 3.78507087 |
46 | primary alcohol catabolic process (GO:0034310) | 3.74528582 |
47 | regulation of guanylate cyclase activity (GO:0031282) | 3.74166457 |
48 | aromatic amino acid family catabolic process (GO:0009074) | 3.71910572 |
49 | kynurenine metabolic process (GO:0070189) | 3.71554142 |
50 | nitrogen cycle metabolic process (GO:0071941) | 3.68229462 |
51 | complement activation, alternative pathway (GO:0006957) | 3.67959176 |
52 | diterpenoid biosynthetic process (GO:0016102) | 3.67622779 |
53 | glutathione biosynthetic process (GO:0006750) | 3.66774566 |
54 | GDP-mannose metabolic process (GO:0019673) | 3.66473972 |
55 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.65753843 |
56 | axoneme assembly (GO:0035082) | 3.64983493 |
57 | desmosome organization (GO:0002934) | 3.64509202 |
58 | indolalkylamine catabolic process (GO:0046218) | 3.63790731 |
59 | tryptophan catabolic process (GO:0006569) | 3.63790731 |
60 | indole-containing compound catabolic process (GO:0042436) | 3.63790731 |
61 | high-density lipoprotein particle remodeling (GO:0034375) | 3.55203136 |
62 | alpha-linolenic acid metabolic process (GO:0036109) | 3.49427584 |
63 | uronic acid metabolic process (GO:0006063) | 3.49299097 |
64 | glucuronate metabolic process (GO:0019585) | 3.49299097 |
65 | water homeostasis (GO:0030104) | 3.48436436 |
66 | ethanol oxidation (GO:0006069) | 3.47795317 |
67 | regulation of cholesterol esterification (GO:0010872) | 3.44277647 |
68 | bile acid metabolic process (GO:0008206) | 3.43028423 |
69 | renal system process involved in regulation of blood volume (GO:0001977) | 3.42634846 |
70 | cholesterol homeostasis (GO:0042632) | 3.39169620 |
71 | nonribosomal peptide biosynthetic process (GO:0019184) | 3.38176283 |
72 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.37099141 |
73 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.37099141 |
74 | regulation of cell-cell adhesion mediated by cadherin (GO:2000047) | 3.36392528 |
75 | plasma lipoprotein particle assembly (GO:0034377) | 3.35761119 |
76 | sterol homeostasis (GO:0055092) | 3.34053062 |
77 | acylglycerol homeostasis (GO:0055090) | 3.33566350 |
78 | triglyceride homeostasis (GO:0070328) | 3.33566350 |
79 | tryptophan metabolic process (GO:0006568) | 3.32074259 |
80 | COPI coating of Golgi vesicle (GO:0048205) | 3.29579784 |
81 | Golgi transport vesicle coating (GO:0048200) | 3.29579784 |
82 | drug transmembrane transport (GO:0006855) | 3.28961335 |
83 | excretion (GO:0007588) | 3.28077704 |
84 | amino-acid betaine metabolic process (GO:0006577) | 3.27818929 |
85 | sphingomyelin metabolic process (GO:0006684) | 3.27035461 |
86 | proline biosynthetic process (GO:0006561) | 3.26289415 |
87 | regulation of protein activation cascade (GO:2000257) | 3.23847513 |
88 | phospholipid homeostasis (GO:0055091) | 3.22821139 |
89 | plasma lipoprotein particle remodeling (GO:0034369) | 3.21487108 |
90 | protein-lipid complex remodeling (GO:0034368) | 3.21487108 |
91 | macromolecular complex remodeling (GO:0034367) | 3.21487108 |
92 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 3.21368131 |
93 | establishment of monopolar cell polarity (GO:0061162) | 3.21368131 |
94 | cellular glucuronidation (GO:0052695) | 3.20522300 |
95 | left/right pattern formation (GO:0060972) | 3.20473784 |
96 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 3.20310704 |
97 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 3.20310704 |
98 | lipoprotein metabolic process (GO:0042157) | 3.19753174 |
99 | reverse cholesterol transport (GO:0043691) | 3.18816677 |
100 | ear development (GO:0043583) | 3.18147240 |
101 | serine family amino acid catabolic process (GO:0009071) | 3.17536073 |
102 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 3.17253978 |
103 | glyoxylate metabolic process (GO:0046487) | 3.16834978 |
104 | bile acid biosynthetic process (GO:0006699) | 3.15978168 |
105 | hepatocyte apoptotic process (GO:0097284) | 3.15338954 |
106 | drug transport (GO:0015893) | 3.13662301 |
107 | regulation of complement activation (GO:0030449) | 3.11323168 |
108 | digestive system process (GO:0022600) | 3.09293682 |
109 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.09158959 |
110 | primary alcohol metabolic process (GO:0034308) | 3.09080458 |
111 | regulation of interleukin-13 production (GO:0032656) | 3.08860995 |
112 | epithelial structure maintenance (GO:0010669) | 3.07702670 |
113 | sulfate transmembrane transport (GO:1902358) | 3.06898304 |
114 | positive regulation of triglyceride metabolic process (GO:0090208) | 3.06763862 |
115 | hemidesmosome assembly (GO:0031581) | 3.05400206 |
116 | angiotensin maturation (GO:0002003) | 3.04435249 |
117 | cellular ketone body metabolic process (GO:0046950) | 3.04037082 |
118 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.03037173 |
119 | tight junction assembly (GO:0070830) | 3.02214281 |
120 | exogenous drug catabolic process (GO:0042738) | 3.01790339 |
121 | protein-lipid complex assembly (GO:0065005) | 3.01505985 |
122 | gap junction assembly (GO:0016264) | 3.00996200 |
123 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 3.00535473 |
124 | cholesterol efflux (GO:0033344) | 2.98460355 |
125 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.97724414 |
126 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.97724414 |
127 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 2.96909909 |
128 | endocrine process (GO:0050886) | 2.96909909 |
129 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 2.96909909 |
130 | regulation of water loss via skin (GO:0033561) | 2.96714822 |
131 | regulation of interleukin-5 production (GO:0032674) | 2.96237118 |
132 | positive regulation of respiratory burst (GO:0060267) | 2.95567968 |
133 | striated muscle atrophy (GO:0014891) | 2.95475913 |
134 | renal absorption (GO:0070293) | 2.94348738 |
135 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.93977076 |
136 | cellular modified amino acid catabolic process (GO:0042219) | 2.93390597 |
137 | proline metabolic process (GO:0006560) | 2.92042713 |
138 | glutamine family amino acid biosynthetic process (GO:0009084) | 2.91390796 |
139 | sodium ion homeostasis (GO:0055078) | 2.91304543 |
140 | epithelial cell-cell adhesion (GO:0090136) | 2.90771154 |
141 | positive regulation of pseudopodium assembly (GO:0031274) | 2.90734879 |
142 | response to nitrosative stress (GO:0051409) | 2.90438422 |
143 | amyloid precursor protein catabolic process (GO:0042987) | 2.90393151 |
144 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.90385580 |
145 | vitamin transport (GO:0051180) | 2.90195222 |
146 | glutathione derivative metabolic process (GO:1901685) | 2.87785715 |
147 | glutathione derivative biosynthetic process (GO:1901687) | 2.87785715 |
148 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.86242729 |
149 | short-chain fatty acid metabolic process (GO:0046459) | 2.85605825 |
150 | aromatic amino acid family metabolic process (GO:0009072) | 2.81323249 |
151 | fat-soluble vitamin biosynthetic process (GO:0042362) | 2.80959999 |
152 | regulation of respiratory burst (GO:0060263) | 2.80746266 |
153 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.79812543 |
154 | hormone catabolic process (GO:0042447) | 2.78755984 |
155 | negative regulation of fibrinolysis (GO:0051918) | 2.78110327 |
156 | drug metabolic process (GO:0017144) | 2.77744229 |
157 | glycine metabolic process (GO:0006544) | 2.76458464 |
158 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.76395225 |
159 | O-glycan processing (GO:0016266) | 2.76155323 |
160 | establishment of skin barrier (GO:0061436) | 2.75699124 |
161 | phenylpropanoid metabolic process (GO:0009698) | 2.75490535 |
162 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 2.75418153 |
163 | sulfur compound transport (GO:0072348) | 2.72030997 |
164 | protein O-linked glycosylation (GO:0006493) | 2.71477993 |
165 | regulation of systemic arterial blood pressure (GO:0003073) | 2.71217818 |
166 | regulation of viral release from host cell (GO:1902186) | 2.70441927 |
167 | retinoic acid metabolic process (GO:0042573) | 2.68891737 |
168 | regulation of cholesterol metabolic process (GO:0090181) | 2.66265400 |
169 | digestion (GO:0007586) | 2.65889408 |
170 | glomerular epithelial cell development (GO:0072310) | 2.64690326 |
171 | glutathione metabolic process (GO:0006749) | 2.63953096 |
172 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.63414995 |
173 | skeletal muscle adaptation (GO:0043501) | 2.62402685 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 6.29684013 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 6.28827186 |
3 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 4.66281816 |
4 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 4.56743374 |
5 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.71296003 |
6 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 3.60047367 |
7 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 3.44986931 |
8 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 3.08929271 |
9 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.87486957 |
10 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.82723982 |
11 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.66547436 |
12 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.43206475 |
13 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.36331777 |
14 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.32866082 |
15 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.32617265 |
16 | GATA4_25053715_ChIP-Seq_YYC3_Human | 2.31384520 |
17 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.29305865 |
18 | GATA6_25053715_ChIP-Seq_YYC3_Human | 2.16816531 |
19 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.08479970 |
20 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.83113146 |
21 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.80726327 |
22 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.71671668 |
23 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.69504874 |
24 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.64335532 |
25 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.62925109 |
26 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.61289289 |
27 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.59818532 |
28 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.56821243 |
29 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.56276821 |
30 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.51705728 |
31 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.50885039 |
32 | ATF3_27146783_Chip-Seq_COLON_Human | 1.48432181 |
33 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.48324362 |
34 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.47814437 |
35 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.47440580 |
36 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.46222839 |
37 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.45831429 |
38 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.45200403 |
39 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.44922637 |
40 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.44666912 |
41 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.44388847 |
42 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.43254865 |
43 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.42671314 |
44 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.41616892 |
45 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.40680648 |
46 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.39658914 |
47 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.39625522 |
48 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.39089476 |
49 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.35569498 |
50 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.31411091 |
51 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.29950378 |
52 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.29545443 |
53 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.29137080 |
54 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.27932935 |
55 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.25471938 |
56 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.25201405 |
57 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.24570015 |
58 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.24479226 |
59 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.24234110 |
60 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.23773761 |
61 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.23046566 |
62 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.22473660 |
63 | GATA1_22025678_ChIP-Seq_K562_Human | 1.21396949 |
64 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.20841899 |
65 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.20704865 |
66 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.16656496 |
67 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.16517886 |
68 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.16198912 |
69 | SA1_27219007_Chip-Seq_Bcells_Human | 1.15376940 |
70 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.15156356 |
71 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.15044448 |
72 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.14515026 |
73 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.13773347 |
74 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.13424083 |
75 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.12914782 |
76 | KDM2B_26808549_Chip-Seq_K562_Human | 1.12819075 |
77 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.11616178 |
78 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.10438352 |
79 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09734667 |
80 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.08688697 |
81 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.08214240 |
82 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.06699954 |
83 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.05617159 |
84 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.04550885 |
85 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.04161285 |
86 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.03712380 |
87 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.01851570 |
88 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.01718127 |
89 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 1.01439894 |
90 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.01250618 |
91 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.00795997 |
92 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.99387851 |
93 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.99224565 |
94 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.99137658 |
95 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.98988956 |
96 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.98048711 |
97 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.97542212 |
98 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.97542212 |
99 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.96718337 |
100 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.96287875 |
101 | * RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.95747001 |
102 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.95628950 |
103 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.94305471 |
104 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.94001521 |
105 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.93996722 |
106 | * KLF5_25053715_ChIP-Seq_YYC3_Human | 0.92119301 |
107 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.90658907 |
108 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.89190745 |
109 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.88586716 |
110 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.88277030 |
111 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.87924870 |
112 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.87702596 |
113 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.87636780 |
114 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.85415591 |
115 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.85114102 |
116 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.84955381 |
117 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.84955381 |
118 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.84955381 |
119 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.84069866 |
120 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.83614193 |
121 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.83600505 |
122 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.83302597 |
123 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.83285227 |
124 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.81863156 |
125 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.81569781 |
126 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.81517014 |
127 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.80898830 |
128 | GATA2_19941826_ChIP-Seq_K562_Human | 0.79472458 |
129 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.78985394 |
130 | * NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.77374037 |
131 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.76675772 |
132 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.76528676 |
133 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.75416820 |
134 | * P68_20966046_ChIP-Seq_HELA_Human | 0.75273428 |
135 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.74208807 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 5.54836998 |
2 | MP0010234_abnormal_vibrissa_follicle | 4.99162298 |
3 | MP0002139_abnormal_hepatobiliary_system | 4.89303541 |
4 | MP0005085_abnormal_gallbladder_physiolo | 4.38774946 |
5 | MP0005365_abnormal_bile_salt | 3.66921454 |
6 | MP0001666_abnormal_nutrient_absorption | 3.64756852 |
7 | MP0004264_abnormal_extraembryonic_tissu | 3.25590538 |
8 | MP0003252_abnormal_bile_duct | 3.11434070 |
9 | MP0008875_abnormal_xenobiotic_pharmacok | 3.09650830 |
10 | MP0000566_synostosis | 2.97122204 |
11 | MP0003806_abnormal_nucleotide_metabolis | 2.83421938 |
12 | MP0009840_abnormal_foam_cell | 2.71215602 |
13 | MP0004043_abnormal_pH_regulation | 2.46185050 |
14 | MP0000678_abnormal_parathyroid_gland | 2.40448971 |
15 | MP0002796_impaired_skin_barrier | 2.34069651 |
16 | MP0010329_abnormal_lipoprotein_level | 2.25002290 |
17 | MP0002254_reproductive_system_inflammat | 2.24424989 |
18 | MP0003300_gastrointestinal_ulcer | 2.23603767 |
19 | MP0003866_abnormal_defecation | 2.16724737 |
20 | MP0001873_stomach_inflammation | 2.15078860 |
21 | MP0004019_abnormal_vitamin_homeostasis | 2.03052386 |
22 | MP0009780_abnormal_chondrocyte_physiolo | 2.02984245 |
23 | MP0003705_abnormal_hypodermis_morpholog | 2.01892060 |
24 | MP0003183_abnormal_peptide_metabolism | 1.99302163 |
25 | MP0005083_abnormal_biliary_tract | 1.98657896 |
26 | MP0005409_darkened_coat_color | 1.93277815 |
27 | MP0010155_abnormal_intestine_physiology | 1.89141136 |
28 | MP0010352_gastrointestinal_tract_polyps | 1.84496430 |
29 | MP0000537_abnormal_urethra_morphology | 1.77843580 |
30 | MP0000462_abnormal_digestive_system | 1.77651826 |
31 | MP0003191_abnormal_cellular_cholesterol | 1.75627095 |
32 | MP0002132_abnormal_respiratory_system | 1.74873323 |
33 | MP0002138_abnormal_hepatobiliary_system | 1.69601579 |
34 | MP0005501_abnormal_skin_physiology | 1.61437450 |
35 | MP0000477_abnormal_intestine_morphology | 1.57980670 |
36 | MP0010678_abnormal_skin_adnexa | 1.55776884 |
37 | MP0000490_abnormal_crypts_of | 1.52671691 |
38 | MP0002653_abnormal_ependyma_morphology | 1.49914697 |
39 | MP0005332_abnormal_amino_acid | 1.48764386 |
40 | MP0000609_abnormal_liver_physiology | 1.48739790 |
41 | MP0002249_abnormal_larynx_morphology | 1.46975766 |
42 | MP0008004_abnormal_stomach_pH | 1.46585031 |
43 | MP0001663_abnormal_digestive_system | 1.44476166 |
44 | MP0002098_abnormal_vibrissa_morphology | 1.44128682 |
45 | MP0003453_abnormal_keratinocyte_physiol | 1.43861703 |
46 | MP0009643_abnormal_urine_homeostasis | 1.43582156 |
47 | MP0003868_abnormal_feces_composition | 1.42791588 |
48 | MP0005076_abnormal_cell_differentiation | 1.42053593 |
49 | MP0005381_digestive/alimentary_phenotyp | 1.34453942 |
50 | MP0004858_abnormal_nervous_system | 1.33985426 |
51 | MP0002876_abnormal_thyroid_physiology | 1.22314476 |
52 | MP0001216_abnormal_epidermal_layer | 1.22110694 |
53 | MP0002277_abnormal_respiratory_mucosa | 1.21639339 |
54 | MP0002118_abnormal_lipid_homeostasis | 1.21513526 |
55 | MP0004947_skin_inflammation | 1.17869668 |
56 | MP0005319_abnormal_enzyme/_coenzyme | 1.17528675 |
57 | MP0004782_abnormal_surfactant_physiolog | 1.14955366 |
58 | MP0003566_abnormal_cell_adhesion | 1.14841253 |
59 | MP0001664_abnormal_digestion | 1.14756459 |
60 | MP0001849_ear_inflammation | 1.10078433 |
61 | MP0005377_hearing/vestibular/ear_phenot | 1.09879942 |
62 | MP0003878_abnormal_ear_physiology | 1.09879942 |
63 | MP0001346_abnormal_lacrimal_gland | 1.08163465 |
64 | MP0002060_abnormal_skin_morphology | 1.05794614 |
65 | MP0001764_abnormal_homeostasis | 1.05750455 |
66 | MP0006054_spinal_hemorrhage | 1.05351321 |
67 | MP0003283_abnormal_digestive_organ | 1.04128593 |
68 | MP0003879_abnormal_hair_cell | 0.96166823 |
69 | MP0005451_abnormal_body_composition | 0.95080994 |
70 | MP0001881_abnormal_mammary_gland | 0.93660280 |
71 | MP0005636_abnormal_mineral_homeostasis | 0.93491439 |
72 | MP0000377_abnormal_hair_follicle | 0.93034146 |
73 | MP0000681_abnormal_thyroid_gland | 0.91731593 |
74 | MP0000467_abnormal_esophagus_morphology | 0.91648539 |
75 | MP0005058_abnormal_lysosome_morphology | 0.91112189 |
76 | MP0004147_increased_porphyrin_level | 0.90323050 |
77 | MP0003693_abnormal_embryo_hatching | 0.88853529 |
78 | MP0000470_abnormal_stomach_morphology | 0.87726668 |
79 | MP0003718_maternal_effect | 0.87434963 |
80 | MP0005670_abnormal_white_adipose | 0.87366943 |
81 | MP0000383_abnormal_hair_follicle | 0.85726148 |
82 | MP0009379_abnormal_foot_pigmentation | 0.85443347 |
83 | MP0002166_altered_tumor_susceptibility | 0.83953778 |
84 | MP0009053_abnormal_anal_canal | 0.83609875 |
85 | MP0002009_preneoplasia | 0.83334841 |
86 | MP0005666_abnormal_adipose_tissue | 0.82474515 |
87 | MP0001188_hyperpigmentation | 0.79054291 |
88 | MP0004185_abnormal_adipocyte_glucose | 0.78318458 |
89 | MP0000598_abnormal_liver_morphology | 0.77983154 |
90 | MP0010771_integument_phenotype | 0.76795583 |
91 | MP0002136_abnormal_kidney_physiology | 0.75095796 |
92 | MP0001765_abnormal_ion_homeostasis | 0.74770887 |
93 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.73965277 |
94 | MP0003941_abnormal_skin_development | 0.73340887 |
95 | MP0002896_abnormal_bone_mineralization | 0.72574061 |
96 | MP0003436_decreased_susceptibility_to | 0.71929023 |
97 | MP0005310_abnormal_salivary_gland | 0.71244913 |
98 | MP0003195_calcinosis | 0.70821624 |
99 | MP0001485_abnormal_pinna_reflex | 0.70362078 |
100 | MP0000538_abnormal_urinary_bladder | 0.70186455 |
101 | MP0002089_abnormal_postnatal_growth/wei | 0.68948438 |
102 | MP0005166_decreased_susceptibility_to | 0.67320147 |
103 | MP0002909_abnormal_adrenal_gland | 0.67204163 |
104 | MP0008469_abnormal_protein_level | 0.67043380 |
105 | MP0002822_catalepsy | 0.66781294 |
106 | MP0001756_abnormal_urination | 0.66768097 |
107 | MP0000613_abnormal_salivary_gland | 0.66385523 |
108 | MP0009785_altered_susceptibility_to | 0.64962321 |
109 | MP0001845_abnormal_inflammatory_respons | 0.64511634 |
110 | MP0005220_abnormal_exocrine_pancreas | 0.64387074 |
111 | MP0005408_hypopigmentation | 0.64340181 |
112 | MP0002006_tumorigenesis | 0.64327336 |
113 | MP0005023_abnormal_wound_healing | 0.63073155 |
114 | MP0010030_abnormal_orbit_morphology | 0.62807223 |
115 | MP0003315_abnormal_perineum_morphology | 0.62307922 |
116 | MP0008260_abnormal_autophagy | 0.61918944 |
117 | MP0004957_abnormal_blastocyst_morpholog | 0.61148675 |
118 | MP0005248_abnormal_Harderian_gland | 0.60529041 |
119 | MP0003638_abnormal_response/metabolism_ | 0.60306114 |
120 | MP0004133_heterotaxia | 0.59873452 |
121 | MP0009931_abnormal_skin_appearance | 0.59868700 |
122 | MP0005165_increased_susceptibility_to | 0.58913561 |
123 | MP0003186_abnormal_redox_activity | 0.58163253 |
124 | MP0000579_abnormal_nail_morphology | 0.57117668 |
125 | MP0009642_abnormal_blood_homeostasis | 0.56886772 |
126 | MP0005025_abnormal_response_to | 0.55996086 |
127 | MP0000465_gastrointestinal_hemorrhage | 0.54169862 |
128 | MP0009765_abnormal_xenobiotic_induced | 0.53930454 |
129 | MP0000627_abnormal_mammary_gland | 0.52858965 |
130 | MP0005167_abnormal_blood-brain_barrier | 0.52640757 |
131 | MP0005647_abnormal_sex_gland | 0.52226606 |
132 | MP0005084_abnormal_gallbladder_morpholo | 0.49379569 |
133 | MP0008872_abnormal_physiological_respon | 0.49255874 |
134 | MP0005464_abnormal_platelet_physiology | 0.49021342 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 8.49062494 |
2 | Abnormal respiratory epithelium morphology (HP:0012253) | 7.28640932 |
3 | Abnormal respiratory motile cilium morphology (HP:0005938) | 7.28640932 |
4 | Abnormal respiratory motile cilium physiology (HP:0012261) | 7.27374898 |
5 | Absent/shortened dynein arms (HP:0200106) | 6.96295568 |
6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.96295568 |
7 | Abnormal ciliary motility (HP:0012262) | 6.95043130 |
8 | Chronic bronchitis (HP:0004469) | 6.78266745 |
9 | Rhinitis (HP:0012384) | 6.64929272 |
10 | Nasal polyposis (HP:0100582) | 5.46343320 |
11 | Intrahepatic cholestasis (HP:0001406) | 5.40485533 |
12 | Bronchiectasis (HP:0002110) | 5.36816379 |
13 | Right ventricular cardiomyopathy (HP:0011663) | 5.31650085 |
14 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 5.21815045 |
15 | Abnormality of the nasal mucosa (HP:0000433) | 4.80473904 |
16 | Hypobetalipoproteinemia (HP:0003563) | 4.66607186 |
17 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.54980196 |
18 | Ileus (HP:0002595) | 4.40877969 |
19 | Xanthomatosis (HP:0000991) | 4.34107723 |
20 | Malnutrition (HP:0004395) | 4.04392302 |
21 | Decreased circulating renin level (HP:0003351) | 3.98565424 |
22 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.94377561 |
23 | Abnormality of renin-angiotensin system (HP:0000847) | 3.76329201 |
24 | Deep venous thrombosis (HP:0002625) | 3.76118307 |
25 | Fat malabsorption (HP:0002630) | 3.66275531 |
26 | Hyperglycinuria (HP:0003108) | 3.56509081 |
27 | Pustule (HP:0200039) | 3.54331637 |
28 | Conjugated hyperbilirubinemia (HP:0002908) | 3.49912632 |
29 | Pili torti (HP:0003777) | 3.49881205 |
30 | Bronchitis (HP:0012387) | 3.43519379 |
31 | Hypolipoproteinemia (HP:0010981) | 3.41995236 |
32 | Hyperammonemia (HP:0001987) | 3.35747419 |
33 | Infertility (HP:0000789) | 3.28259079 |
34 | Abdominal distention (HP:0003270) | 3.24287095 |
35 | Hydroxyprolinuria (HP:0003080) | 3.10082781 |
36 | Abnormality of proline metabolism (HP:0010907) | 3.10082781 |
37 | Male infertility (HP:0003251) | 3.05795558 |
38 | Abnormality of chloride homeostasis (HP:0011422) | 3.05275360 |
39 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 3.04995862 |
40 | Esophageal varix (HP:0002040) | 3.04021918 |
41 | Abnormality of glycine metabolism (HP:0010895) | 3.03352482 |
42 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.03352482 |
43 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.99512685 |
44 | Epidermoid cyst (HP:0200040) | 2.96301505 |
45 | Hypoglycemic coma (HP:0001325) | 2.90752535 |
46 | Prolonged partial thromboplastin time (HP:0003645) | 2.88902639 |
47 | Recurrent otitis media (HP:0000403) | 2.86954911 |
48 | Flat acetabular roof (HP:0003180) | 2.85183704 |
49 | Hyperlipoproteinemia (HP:0010980) | 2.81152926 |
50 | Hyperaldosteronism (HP:0000859) | 2.80735560 |
51 | Abnormality of purine metabolism (HP:0004352) | 2.76683411 |
52 | Onycholysis (HP:0001806) | 2.75992184 |
53 | Recurrent sinusitis (HP:0011108) | 2.75702193 |
54 | Alkalosis (HP:0001948) | 2.69816417 |
55 | Chronic sinusitis (HP:0011109) | 2.67756094 |
56 | Hyperglycinemia (HP:0002154) | 2.67413819 |
57 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.67297373 |
58 | Acanthocytosis (HP:0001927) | 2.66837463 |
59 | Woolly hair (HP:0002224) | 2.65642389 |
60 | Hypoalphalipoproteinemia (HP:0003233) | 2.65161621 |
61 | Hyperkalemia (HP:0002153) | 2.65127151 |
62 | Abnormal hair laboratory examination (HP:0003328) | 2.62954039 |
63 | Abnormality of nucleobase metabolism (HP:0010932) | 2.61616345 |
64 | Atelectasis (HP:0100750) | 2.61250230 |
65 | Complement deficiency (HP:0004431) | 2.61057366 |
66 | Renal salt wasting (HP:0000127) | 2.60899073 |
67 | Hyponatremia (HP:0002902) | 2.60756219 |
68 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.51929468 |
69 | Dicarboxylic aciduria (HP:0003215) | 2.51929468 |
70 | Villous atrophy (HP:0011473) | 2.50682879 |
71 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.50682879 |
72 | Abnormal cartilage morphology (HP:0002763) | 2.49575512 |
73 | Plantar hyperkeratosis (HP:0007556) | 2.48999619 |
74 | Fragile nails (HP:0001808) | 2.47730524 |
75 | Abnormal tarsal ossification (HP:0008369) | 2.47508505 |
76 | Gout (HP:0001997) | 2.43753764 |
77 | Hypercholesterolemia (HP:0003124) | 2.41082354 |
78 | Hyperactive renin-angiotensin system (HP:0000841) | 2.39839905 |
79 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.37382796 |
80 | Milia (HP:0001056) | 2.35946632 |
81 | Alopecia of scalp (HP:0002293) | 2.35786104 |
82 | Late onset (HP:0003584) | 2.35169440 |
83 | Ketosis (HP:0001946) | 2.33756422 |
84 | Micronodular cirrhosis (HP:0001413) | 2.32804282 |
85 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.31482211 |
86 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.31373904 |
87 | Vertebral clefting (HP:0008428) | 2.26097128 |
88 | Vascular calcification (HP:0004934) | 2.25288893 |
89 | Dehydration (HP:0001944) | 2.25207468 |
90 | Thin bony cortex (HP:0002753) | 2.24582493 |
91 | Biliary tract neoplasm (HP:0100574) | 2.23805631 |
92 | Steatorrhea (HP:0002570) | 2.22530262 |
93 | Bell-shaped thorax (HP:0001591) | 2.19307199 |
94 | Abnormality of vitamin metabolism (HP:0100508) | 2.17818383 |
95 | Abnormal biliary tract morphology (HP:0012440) | 2.17302941 |
96 | Abnormality of the common coagulation pathway (HP:0010990) | 2.17299415 |
97 | Widely patent fontanelles and sutures (HP:0004492) | 2.15621841 |
98 | Tubulointerstitial nephritis (HP:0001970) | 2.14834235 |
99 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.14599435 |
100 | Chronic otitis media (HP:0000389) | 2.13477863 |
101 | Abnormality of the intrinsic pathway (HP:0010989) | 2.12387558 |
102 | Hyperbilirubinemia (HP:0002904) | 2.10938709 |
103 | Abnormality of complement system (HP:0005339) | 2.10611433 |
104 | Distal lower limb muscle weakness (HP:0009053) | 2.09274415 |
105 | Cheilitis (HP:0100825) | 2.08011496 |
106 | Abnormality of the gastric mucosa (HP:0004295) | 2.07904908 |
107 | Hypotension (HP:0002615) | 2.07524110 |
108 | Metabolic alkalosis (HP:0200114) | 2.07170328 |
109 | Amelogenesis imperfecta (HP:0000705) | 2.04778137 |
110 | Pancreatitis (HP:0001733) | 2.02103620 |
111 | Stridor (HP:0010307) | 2.01125533 |
112 | Metabolic acidosis (HP:0001942) | 2.00662013 |
113 | Flattened epiphyses (HP:0003071) | 2.00611022 |
114 | Spinal cord compression (HP:0002176) | 2.00267830 |
115 | Spastic diplegia (HP:0001264) | 1.99916960 |
116 | Distal upper limb amyotrophy (HP:0007149) | 1.98781162 |
117 | Upper limb amyotrophy (HP:0009129) | 1.98781162 |
118 | Lethargy (HP:0001254) | 1.97943382 |
119 | Curly hair (HP:0002212) | 1.97832668 |
120 | Hyperphosphatemia (HP:0002905) | 1.95293939 |
121 | Ketoacidosis (HP:0001993) | 1.94488252 |
122 | Myocardial infarction (HP:0001658) | 1.91751133 |
123 | Cardiovascular calcification (HP:0011915) | 1.91676876 |
124 | Occipital encephalocele (HP:0002085) | 1.91503344 |
125 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.91499692 |
126 | Gastrointestinal dysmotility (HP:0002579) | 1.90658638 |
127 | Abnormality of sodium homeostasis (HP:0010931) | 1.89074923 |
128 | Joint hemorrhage (HP:0005261) | 1.88862461 |
129 | Increased purine levels (HP:0004368) | 1.87570651 |
130 | Hyperuricemia (HP:0002149) | 1.87570651 |
131 | Glycosuria (HP:0003076) | 1.85441886 |
132 | Abnormality of urine glucose concentration (HP:0011016) | 1.85441886 |
133 | Abnormal foot bone ossification (HP:0010675) | 1.83657579 |
134 | Abnormal vertebral ossification (HP:0100569) | 1.82497064 |
135 | Hemorrhage of the eye (HP:0011885) | 1.82134686 |
136 | Cone-rod dystrophy (HP:0000548) | 1.81480663 |
137 | Hyperparathyroidism (HP:0000843) | 1.81390806 |
138 | Renal tubular acidosis (HP:0001947) | 1.80523991 |
139 | Abnormal hemoglobin (HP:0011902) | 1.79924348 |
140 | Abnormality of the dental root (HP:0006486) | 1.79875808 |
141 | Taurodontia (HP:0000679) | 1.79875808 |
142 | Abnormality of permanent molar morphology (HP:0011071) | 1.79875808 |
143 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.78317259 |
144 | Hepatocellular carcinoma (HP:0001402) | 1.77902103 |
145 | Abnormality of methionine metabolism (HP:0010901) | 1.77410264 |
146 | Rectal prolapse (HP:0002035) | 1.77252900 |
147 | Abnormality of the 1st metacarpal (HP:0010009) | 1.76974141 |
148 | Hand muscle atrophy (HP:0009130) | 1.76701166 |
149 | Glomerulosclerosis (HP:0000096) | 1.76571597 |
150 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.76429158 |
151 | Proximal tubulopathy (HP:0000114) | 1.76206375 |
152 | Palpitations (HP:0001962) | 1.76148608 |
153 | Posterior subcapsular cataract (HP:0007787) | 1.75474543 |
154 | Poikilocytosis (HP:0004447) | 1.75457408 |
155 | Abnormality of carpal bone ossification (HP:0006257) | 1.75336236 |
156 | Chronic diarrhea (HP:0002028) | 1.74433275 |
157 | Adrenal overactivity (HP:0002717) | 1.73281402 |
158 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.73213513 |
159 | Focal segmental glomerulosclerosis (HP:0000097) | 1.72435034 |
160 | Diaphragmatic weakness (HP:0009113) | 1.69147465 |
161 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.67452746 |
162 | Progressive sensorineural hearing impairment (HP:0000408) | 1.63822467 |
163 | Bronchomalacia (HP:0002780) | 1.63344830 |
164 | Lip pit (HP:0100267) | 1.61519568 |
165 | Abnormality of potassium homeostasis (HP:0011042) | 1.61095150 |
166 | Abnormality of molar (HP:0011077) | 1.60924632 |
167 | Abnormality of molar morphology (HP:0011070) | 1.60924632 |
168 | Abnormality of the dental pulp (HP:0006479) | 1.60662368 |
169 | Cervical subluxation (HP:0003308) | 1.59082069 |
170 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.59074199 |
171 | Growth hormone excess (HP:0000845) | 1.57715186 |
172 | Wide cranial sutures (HP:0010537) | 1.57658826 |
173 | Bifid scrotum (HP:0000048) | 1.53882283 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 4.73690864 |
2 | MST1R | 4.41467535 |
3 | MST4 | 4.03467175 |
4 | TAOK3 | 3.26458589 |
5 | MAP2K2 | 3.20821422 |
6 | SMG1 | 2.93360882 |
7 | PIK3CA | 2.77428795 |
8 | FRK | 2.75291785 |
9 | ERN1 | 2.44841977 |
10 | EPHB2 | 2.25176271 |
11 | LMTK2 | 2.25114846 |
12 | NUAK1 | 2.15303092 |
13 | PTK6 | 2.10638551 |
14 | EEF2K | 1.88960168 |
15 | STK38L | 1.88881806 |
16 | GRK6 | 1.85278551 |
17 | MAP3K10 | 1.85036833 |
18 | PKN2 | 1.81127678 |
19 | BCKDK | 1.78764952 |
20 | RPS6KB2 | 1.78360153 |
21 | FGFR4 | 1.65583394 |
22 | STK39 | 1.64978633 |
23 | MAP3K2 | 1.63353584 |
24 | SIK1 | 1.60687791 |
25 | ACVR1B | 1.59102623 |
26 | MAP3K7 | 1.58704140 |
27 | PRKG2 | 1.55123284 |
28 | TRIB3 | 1.53825131 |
29 | RIPK1 | 1.49223562 |
30 | NME1 | 1.48279405 |
31 | MET | 1.46948395 |
32 | MAPKAPK3 | 1.28151026 |
33 | STK24 | 1.26729725 |
34 | STK10 | 1.18469594 |
35 | SCYL2 | 1.17745601 |
36 | MAP2K6 | 1.15438399 |
37 | PAK4 | 1.15200112 |
38 | LRRK2 | 1.12970337 |
39 | MATK | 1.12577342 |
40 | NEK6 | 1.11540281 |
41 | TAOK1 | 1.09977894 |
42 | ERBB2 | 1.08868563 |
43 | MAP2K1 | 1.08571206 |
44 | FLT3 | 1.03638184 |
45 | EPHB1 | 1.02500661 |
46 | MUSK | 1.00611940 |
47 | TESK2 | 0.98752516 |
48 | MAP3K8 | 0.97785335 |
49 | OXSR1 | 0.96962676 |
50 | MAP3K3 | 0.95454984 |
51 | FER | 0.94354202 |
52 | PTK2 | 0.93574383 |
53 | KSR2 | 0.92475826 |
54 | PRKCI | 0.89862348 |
55 | LATS1 | 0.88796061 |
56 | MAP3K11 | 0.88688700 |
57 | TYK2 | 0.88180245 |
58 | ERBB4 | 0.88135148 |
59 | DMPK | 0.86133350 |
60 | MAP3K12 | 0.85949750 |
61 | MAPK11 | 0.84956145 |
62 | TTK | 0.83130123 |
63 | TESK1 | 0.82308249 |
64 | WNK4 | 0.80666472 |
65 | TEC | 0.79434778 |
66 | CDK6 | 0.77853251 |
67 | TBK1 | 0.77081564 |
68 | PIK3CG | 0.72472284 |
69 | MAP4K1 | 0.70912172 |
70 | MAP3K1 | 0.70810370 |
71 | CSK | 0.64969544 |
72 | RPS6KA2 | 0.64687931 |
73 | NME2 | 0.63092765 |
74 | CDK4 | 0.62650396 |
75 | MAPK15 | 0.61711740 |
76 | AURKB | 0.61604431 |
77 | CDC42BPA | 0.58533989 |
78 | PBK | 0.57607714 |
79 | MYLK | 0.56050210 |
80 | ILK | 0.55805947 |
81 | RAF1 | 0.52017435 |
82 | MAP3K6 | 0.50717386 |
83 | PRKAA2 | 0.50328028 |
84 | KDR | 0.50122565 |
85 | RET | 0.48745841 |
86 | DYRK1B | 0.48554262 |
87 | MARK2 | 0.47828911 |
88 | MAP2K3 | 0.46013042 |
89 | EPHA3 | 0.45360227 |
90 | JAK2 | 0.44273943 |
91 | DDR2 | 0.44258553 |
92 | IRAK3 | 0.41844652 |
93 | CDK12 | 0.41823655 |
94 | FGFR3 | 0.41640247 |
95 | CAMK2G | 0.41639770 |
96 | BTK | 0.40142940 |
97 | PRKD2 | 0.38817389 |
98 | TRPM7 | 0.38307418 |
99 | NEK2 | 0.37504690 |
100 | PDPK1 | 0.35713183 |
101 | IKBKE | 0.32550579 |
102 | ZAP70 | 0.31619412 |
103 | MAP3K14 | 0.31528899 |
104 | CHUK | 0.31344197 |
105 | ICK | 0.30534905 |
106 | RPS6KC1 | 0.30327100 |
107 | RPS6KL1 | 0.30327100 |
108 | NLK | 0.30124950 |
109 | MAPKAPK2 | 0.29002710 |
110 | PRPF4B | 0.28556015 |
111 | PRKCD | 0.28377943 |
112 | ITK | 0.28111876 |
113 | HIPK2 | 0.27193427 |
114 | PAK1 | 0.27122971 |
115 | MTOR | 0.26530017 |
116 | CDK7 | 0.26110113 |
117 | SRC | 0.26091233 |
118 | AKT2 | 0.25528923 |
119 | BMX | 0.24074390 |
120 | STK38 | 0.23772563 |
121 | GRK1 | 0.23716435 |
122 | NEK1 | 0.23602932 |
123 | BLK | 0.23299376 |
124 | TGFBR2 | 0.22538333 |
125 | NEK9 | 0.22445288 |
126 | GSK3A | 0.21490785 |
127 | RPS6KA4 | 0.21209634 |
128 | PRKCZ | 0.21122205 |
129 | PDK1 | 0.20324062 |
130 | ABL2 | 0.20135909 |
131 | RPS6KA6 | 0.19591575 |
132 | DYRK3 | 0.17787971 |
133 | IRAK1 | 0.17609751 |
134 | CAMK2D | 0.15971117 |
135 | MELK | 0.15763884 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.32358978 |
2 | Fat digestion and absorption_Homo sapiens_hsa04975 | 3.07195005 |
3 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.95391385 |
4 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.72451239 |
5 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.51370565 |
6 | Histidine metabolism_Homo sapiens_hsa00340 | 2.40985406 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.39143171 |
8 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.35211826 |
9 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.35190787 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.29004041 |
11 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.12406634 |
12 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.09796079 |
13 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.08549425 |
14 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.04044252 |
15 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.97913328 |
16 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.96901352 |
17 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.84671468 |
18 | Bile secretion_Homo sapiens_hsa04976 | 1.82146518 |
19 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.80546657 |
20 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.77509980 |
21 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.76141037 |
22 | Mineral absorption_Homo sapiens_hsa04978 | 1.75924873 |
23 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.59834128 |
24 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.57840464 |
25 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.53034580 |
26 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.52269391 |
27 | Galactose metabolism_Homo sapiens_hsa00052 | 1.50703352 |
28 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.50140809 |
29 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.49810966 |
30 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.48027540 |
31 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.47035308 |
32 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.45762068 |
33 | Retinol metabolism_Homo sapiens_hsa00830 | 1.42933725 |
34 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.39563376 |
35 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.38673147 |
36 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.38221717 |
37 | Peroxisome_Homo sapiens_hsa04146 | 1.36211648 |
38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.34599441 |
39 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.33143251 |
40 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.32242938 |
41 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.30558989 |
42 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.25948920 |
43 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.25723055 |
44 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.25541984 |
45 | Carbon metabolism_Homo sapiens_hsa01200 | 1.23586061 |
46 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.22881800 |
47 | ABC transporters_Homo sapiens_hsa02010 | 1.21173604 |
48 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.18121838 |
49 | Sulfur relay system_Homo sapiens_hsa04122 | 1.17266707 |
50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.15739176 |
51 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.12506286 |
52 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.08768469 |
53 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.08404183 |
54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.05090568 |
55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.04178719 |
56 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.03272073 |
57 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.99858538 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.97625340 |
59 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.94845102 |
60 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.93256951 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.92364780 |
62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.91383018 |
63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.88500690 |
64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.85764357 |
65 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.79989689 |
66 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.79369133 |
67 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.78266513 |
68 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.75512227 |
69 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.73058232 |
70 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.72086572 |
71 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.70341425 |
72 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59035621 |
73 | Bladder cancer_Homo sapiens_hsa05219 | 0.58947254 |
74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58413777 |
75 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.58324201 |
76 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.57592234 |
77 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.54304011 |
78 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.49043144 |
79 | Adherens junction_Homo sapiens_hsa04520 | 0.48168744 |
80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.47999586 |
81 | Lysine degradation_Homo sapiens_hsa00310 | 0.47941419 |
82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47694086 |
83 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.46456953 |
84 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.46419870 |
85 | * Tight junction_Homo sapiens_hsa04530 | 0.45938967 |
86 | Thyroid cancer_Homo sapiens_hsa05216 | 0.43953668 |
87 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.43367449 |
88 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.41260038 |
89 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.40787957 |
90 | Hepatitis C_Homo sapiens_hsa05160 | 0.40159351 |
91 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39825930 |
92 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.37967215 |
93 | Other glycan degradation_Homo sapiens_hsa00511 | 0.34941675 |
94 | Ribosome_Homo sapiens_hsa03010 | 0.34699853 |
95 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.34297768 |
96 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.32323927 |
97 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.29636218 |
98 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.29348181 |
99 | Endometrial cancer_Homo sapiens_hsa05213 | 0.29179310 |
100 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.28588909 |
101 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.28453819 |
102 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.27877913 |
103 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.27036075 |
104 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.23372327 |
105 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.23304348 |
106 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.23229247 |
107 | Insulin resistance_Homo sapiens_hsa04931 | 0.22730956 |
108 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.21948681 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.20452573 |
110 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.17783008 |
111 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.14608594 |
112 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.14439315 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.14036239 |
114 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.13885927 |
115 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.13617961 |
116 | Lysosome_Homo sapiens_hsa04142 | 0.13330981 |
117 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.11421723 |
118 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.11209040 |
119 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.09209976 |
120 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.08852282 |
121 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.08286530 |
122 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.08085828 |