TM9SF3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)5.82568578
2COPI coating of Golgi vesicle (GO:0048205)5.82568578
3protein localization to endosome (GO:0036010)4.34348253
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.29188962
5desmosome organization (GO:0002934)4.10071001
6activation of signaling protein activity involved in unfolded protein response (GO:0006987)4.09757331
7nuclear pore complex assembly (GO:0051292)3.99387395
8positive regulation of nuclease activity (GO:0032075)3.93693443
9apoptotic cell clearance (GO:0043277)3.91931884
10endoplasmic reticulum unfolded protein response (GO:0030968)3.66921642
11bundle of His cell to Purkinje myocyte communication (GO:0086069)3.61870286
12retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.58711394
13cell adhesion mediated by integrin (GO:0033627)3.58618128
14COPII vesicle coating (GO:0048208)3.58293675
15protein retention in ER lumen (GO:0006621)3.52884294
16regulation of nuclease activity (GO:0032069)3.51256149
17cellular response to unfolded protein (GO:0034620)3.49509154
18ER-nucleus signaling pathway (GO:0006984)3.45824359
19nuclear pore organization (GO:0006999)3.40819168
20embryonic process involved in female pregnancy (GO:0060136)3.39102178
21epithelial cell-cell adhesion (GO:0090136)3.33871779
22growth hormone receptor signaling pathway (GO:0060396)3.30182266
23vesicle coating (GO:0006901)3.28742125
24UDP-N-acetylglucosamine metabolic process (GO:0006047)3.20342328
254-hydroxyproline metabolic process (GO:0019471)3.19850630
26insulin-like growth factor receptor signaling pathway (GO:0048009)3.18712624
27ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.18477688
28cellular response to topologically incorrect protein (GO:0035967)3.16415360
29epithelial cell differentiation involved in prostate gland development (GO:0060742)3.15179370
30regulation of transforming growth factor beta1 production (GO:0032908)3.11393565
31N-glycan processing (GO:0006491)3.07974184
32cell-substrate junction assembly (GO:0007044)3.06397374
33branching involved in prostate gland morphogenesis (GO:0060442)3.05239167
34response to endoplasmic reticulum stress (GO:0034976)3.03895718
35gap junction assembly (GO:0016264)3.00915894
36iron ion import (GO:0097286)2.95871486
37paraxial mesoderm development (GO:0048339)2.95715898
38regulation of cholesterol homeostasis (GO:2000188)2.95419971
39sequestering of metal ion (GO:0051238)2.94957907
40regulation of RNA export from nucleus (GO:0046831)2.93981618
41cytoplasmic mRNA processing body assembly (GO:0033962)2.93192768
42negative regulation of fatty acid transport (GO:2000192)2.92401186
43cytoskeletal anchoring at plasma membrane (GO:0007016)2.90619771
44cellular response to vitamin D (GO:0071305)2.89963145
45cellular response to growth hormone stimulus (GO:0071378)2.86419025
46alpha-linolenic acid metabolic process (GO:0036109)2.86208653
47dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.86189914
48planar cell polarity pathway involved in neural tube closure (GO:0090179)2.85615825
49regulation of transforming growth factor beta2 production (GO:0032909)2.84584292
50branching involved in mammary gland duct morphogenesis (GO:0060444)2.81718045
51cellular response to vitamin (GO:0071295)2.79664980
52regulation of nucleobase-containing compound transport (GO:0032239)2.79449605
53adherens junction assembly (GO:0034333)2.78595164
54negative regulation of anoikis (GO:2000811)2.75383364
55hypotonic response (GO:0006971)2.74761321
56transcytosis (GO:0045056)2.74087144
57regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.72004667
58retina vasculature morphogenesis in camera-type eye (GO:0061299)2.70723771
59chondrocyte development (GO:0002063)2.69792967
60positive regulation of histone deacetylation (GO:0031065)2.68488470
61cellular protein complex localization (GO:0034629)2.67267534
62chondrocyte proliferation (GO:0035988)2.67197497
63valine metabolic process (GO:0006573)2.66910139
64mesodermal cell differentiation (GO:0048333)2.66844280
65basement membrane organization (GO:0071711)2.66689548
66hemidesmosome assembly (GO:0031581)2.65946370
67sulfur amino acid catabolic process (GO:0000098)2.65891736
68hormone catabolic process (GO:0042447)2.65370765
69positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.64292665
70very-low-density lipoprotein particle assembly (GO:0034379)2.63750055
71cell-substrate adherens junction assembly (GO:0007045)2.63200669
72focal adhesion assembly (GO:0048041)2.63200669
73surfactant homeostasis (GO:0043129)2.62929800
74membrane protein ectodomain proteolysis (GO:0006509)2.62430713
75Golgi organization (GO:0007030)2.61942596
76intestinal epithelial cell development (GO:0060576)2.60464111
77hippo signaling (GO:0035329)2.60230417
78regulation of early endosome to late endosome transport (GO:2000641)2.59353662
79pore complex assembly (GO:0046931)2.59281894
80germ cell migration (GO:0008354)2.58854900
81mannose metabolic process (GO:0006013)2.58853525
82receptor catabolic process (GO:0032801)2.58392335
83response to unfolded protein (GO:0006986)2.57536931
84negative regulation of protein localization to plasma membrane (GO:1903077)2.57369142
85regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.56626365
86negative regulation of keratinocyte proliferation (GO:0010839)2.55556442
87negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.55252769
88peptidyl-asparagine modification (GO:0018196)2.54705378
89protein N-linked glycosylation via asparagine (GO:0018279)2.54634403
90positive regulation of endothelial cell apoptotic process (GO:2000353)2.54091092
91negative regulation of lipid transport (GO:0032369)2.53566675
92mRNA stabilization (GO:0048255)2.52454860
93RNA stabilization (GO:0043489)2.52454860
94regulation of membrane protein ectodomain proteolysis (GO:0051043)2.51743103
95cortical actin cytoskeleton organization (GO:0030866)2.51633079
96collagen fibril organization (GO:0030199)2.50016015
97mitotic sister chromatid cohesion (GO:0007064)2.49148391
98skin morphogenesis (GO:0043589)2.48814430
99phospholipid translocation (GO:0045332)2.48214780
100lipid translocation (GO:0034204)2.48214780
101positive regulation of establishment of protein localization to plasma membrane (GO:0090004)2.48055634
102exocrine pancreas development (GO:0031017)2.44232545
103positive regulation of protein localization to plasma membrane (GO:1903078)2.43260722
104low-density lipoprotein particle clearance (GO:0034383)2.43194918
105regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.42855505
106positive regulation of glycoprotein metabolic process (GO:1903020)2.41833097
107antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.41763255
108antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.41763255
109regulation of protein localization to plasma membrane (GO:1903076)2.41316859
110regulation of fatty acid beta-oxidation (GO:0031998)2.41140724
111regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.39048966
112response to topologically incorrect protein (GO:0035966)2.38333846
113positive regulation of fatty acid beta-oxidation (GO:0032000)2.37979995
114maternal placenta development (GO:0001893)2.37616374
115dorsal/ventral axis specification (GO:0009950)2.37367108
116regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.36836946
117prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.36722239
118embryonic camera-type eye morphogenesis (GO:0048596)2.36270917
119angiotensin maturation (GO:0002003)2.35914341
120protein N-linked glycosylation (GO:0006487)2.35832804
121establishment of protein localization to Golgi (GO:0072600)2.35569176
122peptidyl-proline hydroxylation (GO:0019511)2.35084918
123cell migration involved in sprouting angiogenesis (GO:0002042)2.34401569
124intestinal absorption (GO:0050892)2.33233145
125regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.33151188
126nucleotide-sugar biosynthetic process (GO:0009226)2.32905665
127stress fiber assembly (GO:0043149)2.32798888
128positive regulation of cellular response to insulin stimulus (GO:1900078)2.31543003
129apical protein localization (GO:0045176)2.31478449
130protein localization to cell surface (GO:0034394)2.31190288
131cell-cell junction assembly (GO:0007043)2.31165657
132wound healing, spreading of epidermal cells (GO:0035313)2.31120086
133protein targeting to Golgi (GO:0000042)2.31104961
134regulation of glucose import in response to insulin stimulus (GO:2001273)2.31022516
135endoplasmic reticulum organization (GO:0007029)2.31019797
136tight junction assembly (GO:0070830)2.30310411
137establishment of apical/basal cell polarity (GO:0035089)2.29568617
138regulation of transforming growth factor beta production (GO:0071634)2.29501263
139negative regulation of DNA repair (GO:0045738)2.29441075
140regulation of anoikis (GO:2000209)2.28884731
141drug transmembrane transport (GO:0006855)2.28407514
142ER overload response (GO:0006983)2.26849903
143regulation of establishment of protein localization to plasma membrane (GO:0090003)2.26793953
144regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.26638070
145notochord development (GO:0030903)2.26278946
146barbed-end actin filament capping (GO:0051016)2.25573310
147protein carboxylation (GO:0018214)2.25538600
148peptidyl-glutamic acid carboxylation (GO:0017187)2.25538600
149negative regulation of chondrocyte differentiation (GO:0032331)2.25225569
150positive regulation of osteoblast proliferation (GO:0033690)2.24666119
151sequestering of extracellular ligand from receptor (GO:0035581)2.24582112
152embryonic retina morphogenesis in camera-type eye (GO:0060059)2.24045668
153multicellular organismal catabolic process (GO:0044243)2.23863969
154receptor recycling (GO:0001881)2.23815324
155multicellular organismal macromolecule metabolic process (GO:0044259)2.23496137
156endodermal cell differentiation (GO:0035987)2.22768731
157localization within membrane (GO:0051668)2.22153238
158collagen metabolic process (GO:0032963)2.22012948
159protein hydroxylation (GO:0018126)2.21854983
160multicellular organismal metabolic process (GO:0044236)2.20933614
161midgut development (GO:0007494)2.20573530
162positive regulation of glycogen biosynthetic process (GO:0045725)2.20482457
163regulation of polysaccharide biosynthetic process (GO:0032885)2.20333948
164glycoprotein catabolic process (GO:0006516)2.19140811
165collagen catabolic process (GO:0030574)2.19084088
166cysteine metabolic process (GO:0006534)2.18959904
167retrograde transport, vesicle recycling within Golgi (GO:0000301)2.18524963

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.08114192
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.63618029
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.45433843
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.42061548
5CLOCK_20551151_ChIP-Seq_293T_Human3.35199702
6* AR_21909140_ChIP-Seq_LNCAP_Human3.32458376
7TRIM28_21343339_ChIP-Seq_HEK293_Human3.22327406
8LXR_22158963_ChIP-Seq_LIVER_Mouse2.53283206
9* RXR_22158963_ChIP-Seq_LIVER_Mouse2.50090537
10STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.40200223
11FOXO3_23340844_ChIP-Seq_DLD1_Human2.31370111
12PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.25833496
13* PPARA_22158963_ChIP-Seq_LIVER_Mouse2.24769861
14E2F7_22180533_ChIP-Seq_HELA_Human2.22959529
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.21274232
16* SOX2_27498859_Chip-Seq_STOMACH_Mouse2.19078966
17SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.17268900
18RARG_19884340_ChIP-ChIP_MEFs_Mouse2.00823233
19GATA1_22025678_ChIP-Seq_K562_Human2.00134088
20SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.94584986
21ZNF217_24962896_ChIP-Seq_MCF-7_Human1.93265290
22EGR1_19374776_ChIP-ChIP_THP-1_Human1.91653311
23PPAR_26484153_Chip-Seq_NCI-H1993_Human1.88203068
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.87705250
25ZNF263_19887448_ChIP-Seq_K562_Human1.86622570
26SOX2_20726797_ChIP-Seq_SW620_Human1.85547132
27ESR2_21235772_ChIP-Seq_MCF-7_Human1.84040120
28* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.81471309
29* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.79789745
30NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.76490545
31ESR1_21235772_ChIP-Seq_MCF-7_Human1.75286637
32ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.74902935
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.72604821
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.71230405
35KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.68670710
36TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.67975989
37* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.65221445
38NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.64575069
39NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.63864553
40NRF2_20460467_ChIP-Seq_MEFs_Mouse1.63864553
41ESR1_20079471_ChIP-ChIP_T-47D_Human1.63830560
42CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.62842703
43FOXM1_23109430_ChIP-Seq_U2OS_Human1.60557875
44SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.59937545
45SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.59937545
46GATA4_25053715_ChIP-Seq_YYC3_Human1.56065982
47TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55663717
48EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.53444191
49GATA6_25053715_ChIP-Seq_YYC3_Human1.53207499
50CJUN_26792858_Chip-Seq_BT549_Human1.52487885
51SALL4_18804426_ChIP-ChIP_XEN_Mouse1.51978069
52* FOXA2_19822575_ChIP-Seq_HepG2_Human1.50740787
53* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.50124475
54* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.49294352
55TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.44705350
56CDX2_20551321_ChIP-Seq_CACO-2_Human1.44212559
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.43926831
58TP53_16413492_ChIP-PET_HCT116_Human1.42996617
59KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.42590007
60* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.41484766
61GATA2_21666600_ChIP-Seq_HMVEC_Human1.41474388
62WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.40736272
63RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.40687076
64STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.39701224
65CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38996186
66BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.38772352
67TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.37394582
68TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.35530366
69ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.32871014
70Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.32410295
71STAT6_21828071_ChIP-Seq_BEAS2B_Human1.32399089
72STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.32385901
73* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.31615826
74POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.30950627
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.30927144
76* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.30893121
77PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.27890363
78SALL1_21062744_ChIP-ChIP_HESCs_Human1.27602681
79TCF4_18268006_ChIP-ChIP_LS174T_Human1.27468332
80CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.26176226
81SMAD_19615063_ChIP-ChIP_OVARY_Human1.24985163
82* BRD4_25478319_ChIP-Seq_HGPS_Human1.23883118
83TCF3_18692474_ChIP-Seq_MEFs_Mouse1.23640874
84STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.21896739
85ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21502538
86FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21054716
87RUNX1_27514584_Chip-Seq_MCF-7_Human1.19716437
88ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.19089619
89FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.19045564
90* EP300_21415370_ChIP-Seq_HL-1_Mouse1.17400373
91KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.17247947
92ATF3_27146783_Chip-Seq_COLON_Human1.17077933
93ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16717593
94CHD1_26751641_Chip-Seq_LNCaP_Human1.16705896
95GATA3_24758297_ChIP-Seq_MCF-7_Human1.16299833
96* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.15567264
97KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14690667
98MYB_21317192_ChIP-Seq_ERMYB_Mouse1.13544866
99TP63_23658742_ChIP-Seq_EP156T_Human1.11930958
100BRD4_27068464_Chip-Seq_AML-cells_Mouse1.11072416
101NFIB_24661679_ChIP-Seq_LUNG_Mouse1.10403690
102PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.10345714
103* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.08875108
104AHR_22903824_ChIP-Seq_MCF-7_Human1.08837744
105FOXA1_25552417_ChIP-Seq_VCAP_Human1.07757213
106PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.07295772
107FOXM1_26456572_ChIP-Seq_MCF-7_Human1.06668671
108NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.06516697
109CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03719952
110* UBF1/2_26484160_Chip-Seq_HMECs_Human1.03254398
111RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.02763669
112RXR_22108803_ChIP-Seq_LS180_Human1.02523113
113HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.02090444
114SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.01938731
115RACK7_27058665_Chip-Seq_MCF-7_Human1.01505624
116HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01003453
117ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00396986
118* TBX20_22080862_ChIP-Seq_HEART_Mouse0.99372954
119* TBX20_22328084_ChIP-Seq_HEART_Mouse0.99372954
120TCF7_22412390_ChIP-Seq_EML_Mouse0.98844163
121ELK3_25401928_ChIP-Seq_HUVEC_Human0.98333546
122DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.98047021
123KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.97830582
124ARNT_22903824_ChIP-Seq_MCF-7_Human0.97586771
125YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96996913
126TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.94715385

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle4.92643558
2MP0003300_gastrointestinal_ulcer4.30451620
3MP0008438_abnormal_cutaneous_collagen3.70770608
4MP0003705_abnormal_hypodermis_morpholog3.65589880
5MP0002139_abnormal_hepatobiliary_system3.17290127
6MP0006054_spinal_hemorrhage2.90604341
7MP0010352_gastrointestinal_tract_polyps2.67405677
8MP0003941_abnormal_skin_development2.52222489
9MP0003252_abnormal_bile_duct2.26812390
10MP0005275_abnormal_skin_tensile2.26398346
11MP0002877_abnormal_melanocyte_morpholog2.24112045
12MP0009780_abnormal_chondrocyte_physiolo2.19365923
13MP0005409_darkened_coat_color2.18816822
14MP0005360_urolithiasis2.09875354
15MP0002166_altered_tumor_susceptibility2.04859511
16MP0009384_cardiac_valve_regurgitation2.01768955
17MP0001666_abnormal_nutrient_absorption2.00148318
18MP0004272_abnormal_basement_membrane1.96968295
19MP0005365_abnormal_bile_salt1.96079138
20MP0000537_abnormal_urethra_morphology1.89863807
21MP0003566_abnormal_cell_adhesion1.80419173
22MP0002896_abnormal_bone_mineralization1.74549572
23MP0005257_abnormal_intraocular_pressure1.73108187
24MP0010678_abnormal_skin_adnexa1.68656013
25MP0003191_abnormal_cellular_cholesterol1.54273081
26MP0005058_abnormal_lysosome_morphology1.50470445
27MP0001958_emphysema1.49605330
28MP0004185_abnormal_adipocyte_glucose1.49113981
29MP0005220_abnormal_exocrine_pancreas1.47495630
30MP0005085_abnormal_gallbladder_physiolo1.46723398
31MP0005076_abnormal_cell_differentiation1.45766332
32MP0002060_abnormal_skin_morphology1.44967464
33MP0004782_abnormal_surfactant_physiolog1.43760901
34MP0003045_fibrosis1.43695921
35MP0005501_abnormal_skin_physiology1.41843781
36MP0000013_abnormal_adipose_tissue1.38807829
37MP0004264_abnormal_extraembryonic_tissu1.37786164
38MP0005623_abnormal_meninges_morphology1.36559819
39MP0003868_abnormal_feces_composition1.35719898
40MP0000762_abnormal_tongue_morphology1.33663309
41MP0002006_tumorigenesis1.26904534
42MP0003303_peritoneal_inflammation1.25460565
43MP0004858_abnormal_nervous_system1.22760614
44MP0003091_abnormal_cell_migration1.22105910
45MP0002086_abnormal_extraembryonic_tissu1.19319485
46MP0005023_abnormal_wound_healing1.18403588
47MP0001730_embryonic_growth_arrest1.16101965
48MP0010329_abnormal_lipoprotein_level1.16075455
49MP0001299_abnormal_eye_distance/1.15384451
50MP0004957_abnormal_blastocyst_morpholog1.14372113
51MP0002098_abnormal_vibrissa_morphology1.12288963
52MP0003183_abnormal_peptide_metabolism1.08878874
53MP0003890_abnormal_embryonic-extraembry1.08614712
54MP0001915_intracranial_hemorrhage1.08391681
55MP0004130_abnormal_muscle_cell1.06092553
56MP0003984_embryonic_growth_retardation1.06027138
57MP0002009_preneoplasia1.05701358
58MP0008004_abnormal_stomach_pH1.05436606
59MP0000627_abnormal_mammary_gland1.05054873
60MP0002909_abnormal_adrenal_gland1.04715665
61MP0001765_abnormal_ion_homeostasis1.04423678
62MP0003195_calcinosis1.04250102
63MP0000428_abnormal_craniofacial_morphol1.04073778
64MP0009643_abnormal_urine_homeostasis1.03502242
65MP0003453_abnormal_keratinocyte_physiol1.03039571
66MP0008875_abnormal_xenobiotic_pharmacok1.02966271
67MP0000003_abnormal_adipose_tissue1.02490915
68MP0002088_abnormal_embryonic_growth/wei1.01800938
69MP0005380_embryogenesis_phenotype1.00799824
70MP0001672_abnormal_embryogenesis/_devel1.00799824
71MP0005408_hypopigmentation0.99836426
72MP0001944_abnormal_pancreas_morphology0.99282746
73MP0005083_abnormal_biliary_tract0.99005192
74MP0000465_gastrointestinal_hemorrhage0.98901759
75MP0000604_amyloidosis0.98790912
76MP0001873_stomach_inflammation0.97871365
77MP0009053_abnormal_anal_canal0.97388645
78MP0005666_abnormal_adipose_tissue0.97284375
79MP0000767_abnormal_smooth_muscle0.96585830
80MP0002295_abnormal_pulmonary_circulatio0.96402340
81MP0002084_abnormal_developmental_patter0.95104502
82MP0004043_abnormal_pH_regulation0.95089581
83MP0002697_abnormal_eye_size0.94847704
84MP0008057_abnormal_DNA_replication0.94380437
85MP0005375_adipose_tissue_phenotype0.92813892
86MP0003950_abnormal_plasma_membrane0.92389436
87MP0004947_skin_inflammation0.92022046
88MP0009672_abnormal_birth_weight0.91978455
89MP0000534_abnormal_ureter_morphology0.91623004
90MP0000609_abnormal_liver_physiology0.89722238
91MP0003283_abnormal_digestive_organ0.88824315
92MP0000432_abnormal_head_morphology0.88767687
93MP0001756_abnormal_urination0.87777804
94MP0000467_abnormal_esophagus_morphology0.86986945
95MP0000462_abnormal_digestive_system0.86262455
96MP0000733_abnormal_muscle_development0.85518515
97MP0001881_abnormal_mammary_gland0.84966655
98MP0005621_abnormal_cell_physiology0.83472353
99MP0000579_abnormal_nail_morphology0.83059502
100MP0000350_abnormal_cell_proliferation0.82944080
101MP0002928_abnormal_bile_duct0.81950473
102MP0002925_abnormal_cardiovascular_devel0.81557414
103MP0010155_abnormal_intestine_physiology0.81118700
104MP0005503_abnormal_tendon_morphology0.81080698
105MP0003315_abnormal_perineum_morphology0.80915844
106MP0000377_abnormal_hair_follicle0.80710299
107MP0002168_other_aberrant_phenotype0.80059925
108MP0006138_congestive_heart_failure0.79691362
109MP0005187_abnormal_penis_morphology0.79582622
110MP0001879_abnormal_lymphatic_vessel0.79093466
111MP0002796_impaired_skin_barrier0.78511302
112MP0002085_abnormal_embryonic_tissue0.77861781
113MP0002118_abnormal_lipid_homeostasis0.77820807
114MP0003279_aneurysm0.77202961
115MP0001243_abnormal_dermal_layer0.76858157
116MP0003385_abnormal_body_wall0.76609849
117MP0003115_abnormal_respiratory_system0.76008438
118MP0005332_abnormal_amino_acid0.75748461
119MP0000490_abnormal_crypts_of0.75674086
120MP0010368_abnormal_lymphatic_system0.74923899
121MP0001533_abnormal_skeleton_physiology0.74445703
122MP0003448_altered_tumor_morphology0.74013419
123MP0000858_altered_metastatic_potential0.73589783
124MP0005167_abnormal_blood-brain_barrier0.73533240
125MP0001849_ear_inflammation0.73445607
126MP0004233_abnormal_muscle_weight0.73188327
127MP0003795_abnormal_bone_structure0.73077000
128MP0002092_abnormal_eye_morphology0.72520858
129MP0002080_prenatal_lethality0.72381490
130MP0003828_pulmonary_edema0.72025833
131MP0003866_abnormal_defecation0.71419921
132MP0010630_abnormal_cardiac_muscle0.71241158
133MP0002115_abnormal_skeleton_extremities0.71061291
134MP0001614_abnormal_blood_vessel0.70835322
135MP0000477_abnormal_intestine_morphology0.69866322
136MP0001697_abnormal_embryo_size0.68950022
137MP0002998_abnormal_bone_remodeling0.68271728
138MP0000383_abnormal_hair_follicle0.67562507
139MP0010307_abnormal_tumor_latency0.67105407
140MP0000613_abnormal_salivary_gland0.65436412
141MP0002136_abnormal_kidney_physiology0.65110762
142MP0003329_amyloid_beta_deposits0.64918188
143MP0005310_abnormal_salivary_gland0.64769546
144MP0000569_abnormal_digit_pigmentation0.64024429
145MP0002254_reproductive_system_inflammat0.63639241
146MP0001216_abnormal_epidermal_layer0.63449512
147MP0005248_abnormal_Harderian_gland0.62185005
148MP0000163_abnormal_cartilage_morphology0.61897715

Predicted human phenotypes

RankGene SetZ-score
1Aortic aneurysm (HP:0004942)3.47094070
2Premature rupture of membranes (HP:0001788)3.38519355
3Aortic dissection (HP:0002647)3.35619304
4Subacute progressive viral hepatitis (HP:0006572)3.20854283
5Cerebral aneurysm (HP:0004944)3.13749580
6Protrusio acetabuli (HP:0003179)3.13551226
7Hematochezia (HP:0002573)3.01150162
8Mitral valve prolapse (HP:0001634)2.88596683
9Rectal prolapse (HP:0002035)2.76204700
10Atrophic scars (HP:0001075)2.72987992
11Osteolytic defects of the phalanges of the hand (HP:0009771)2.70655328
12Osteolytic defects of the hand bones (HP:0009699)2.70655328
13Cervical subluxation (HP:0003308)2.66317144
14Neonatal short-limb short stature (HP:0008921)2.56278454
15Deep venous thrombosis (HP:0002625)2.52125410
16Abnormality of the distal phalanx of the thumb (HP:0009617)2.50459948
17Peritonitis (HP:0002586)2.48592504
18Aneurysm (HP:0002617)2.46803413
19Abnormality of the intrinsic pathway (HP:0010989)2.46687672
20Abnormality of the common coagulation pathway (HP:0010990)2.46321578
21Dilatation of the ascending aorta (HP:0005111)2.46273388
22Macroorchidism (HP:0000053)2.44971501
23Thin bony cortex (HP:0002753)2.42510135
24Abnormal foot bone ossification (HP:0010675)2.42168156
25Syringomyelia (HP:0003396)2.40752623
26Spinal cord lesions (HP:0100561)2.40752623
27Arterial tortuosity (HP:0005116)2.39062924
28Urinary glycosaminoglycan excretion (HP:0003541)2.38643512
29Mucopolysacchariduria (HP:0008155)2.38643512
30Shallow orbits (HP:0000586)2.35259208
31Buphthalmos (HP:0000557)2.34931446
32Tetraparesis (HP:0002273)2.34110103
33Ankle contracture (HP:0006466)2.32685678
34Short nail (HP:0001799)2.31682282
35Abnormality of carpal bone ossification (HP:0006257)2.31007454
36Vascular tortuosity (HP:0004948)2.24613730
37Papilledema (HP:0001085)2.23961707
38Intrahepatic cholestasis (HP:0001406)2.22575798
39Absent frontal sinuses (HP:0002688)2.22264953
40Vertebral compression fractures (HP:0002953)2.22212535
41Back pain (HP:0003418)2.21903290
42Thoracolumbar scoliosis (HP:0002944)2.20752161
43Myocardial infarction (HP:0001658)2.20439586
44Dysostosis multiplex (HP:0000943)2.17079672
45Ankyloglossia (HP:0010296)2.16036776
46Ulnar bowing (HP:0003031)2.14648581
47Vertebral arch anomaly (HP:0008438)2.14596772
48Abnormality of oral frenula (HP:0000190)2.14400253
49Spastic diplegia (HP:0001264)2.13812852
50Severe short stature (HP:0003510)2.12886315
51Increased mean platelet volume (HP:0011877)2.12637091
52Abdominal distention (HP:0003270)2.12519788
53Fragile skin (HP:0001030)2.12006522
54Abnormal ossification of hand bones (HP:0005921)2.11554555
55Epiphyseal dysplasia (HP:0002656)2.10966447
56Flat acetabular roof (HP:0003180)2.10591455
57Exostoses (HP:0100777)2.07815542
58Micronodular cirrhosis (HP:0001413)2.05045406
59Curly hair (HP:0002212)2.04114965
60Papillary thyroid carcinoma (HP:0002895)2.03496010
61Abnormality of the distal phalanges of the toes (HP:0010182)2.03398725
62Lymphangioma (HP:0100764)2.02945302
63Xanthomatosis (HP:0000991)2.02482561
64Focal segmental glomerulosclerosis (HP:0000097)2.02163447
65Abnormality of the lumbar spine (HP:0100712)2.01378677
66Hyperextensible skin (HP:0000974)2.00892333
67Abnormality of glycosaminoglycan metabolism (HP:0004371)1.99832663
68Abnormality of mucopolysaccharide metabolism (HP:0011020)1.99832663
69Abnormality of polysaccharide metabolism (HP:0011012)1.99832663
70Enlarged penis (HP:0000040)1.99693236
71Protuberant abdomen (HP:0001538)1.99480711
72Abnormality of the acetabulum (HP:0003170)1.98334201
73Overgrowth (HP:0001548)1.97663699
74Increased density of long bones (HP:0006392)1.95248408
75Missing ribs (HP:0000921)1.94440410
76Abnormality of dentin (HP:0010299)1.91847610
77Wormian bones (HP:0002645)1.91374364
78Hallux valgus (HP:0001822)1.91121702
79Increased CSF protein (HP:0002922)1.90697847
80Right ventricular cardiomyopathy (HP:0011663)1.90129573
81Radial bowing (HP:0002986)1.89810031
82Deviation of the hallux (HP:0010051)1.89509219
83Cardiovascular calcification (HP:0011915)1.89255874
84Scapular winging (HP:0003691)1.86899522
85Hypoglycemic coma (HP:0001325)1.86443512
86Upper limb amyotrophy (HP:0009129)1.84936232
87Distal upper limb amyotrophy (HP:0007149)1.84936232
88Broad ribs (HP:0000885)1.84762331
89Insidious onset (HP:0003587)1.84561332
90Termporal pattern (HP:0011008)1.84561332
91Abnormal hand bone ossification (HP:0010660)1.84513582
92Bladder diverticulum (HP:0000015)1.83826286
93Glomerulosclerosis (HP:0000096)1.83778693
94Abnormality of the Achilles tendon (HP:0005109)1.83638601
95Spinal cord compression (HP:0002176)1.83429439
96Advanced eruption of teeth (HP:0006288)1.82211792
97Abnormal platelet volume (HP:0011876)1.82134205
98Broad metatarsal (HP:0001783)1.82074412
99Hand muscle atrophy (HP:0009130)1.81789850
100Persistence of primary teeth (HP:0006335)1.81353577
101Vertebral hypoplasia (HP:0008417)1.80748837
102Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.80748837
103Achilles tendon contracture (HP:0001771)1.80054928
104Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.79472182
105Abnormal vertebral ossification (HP:0100569)1.79168328
106Abnormal tarsal ossification (HP:0008369)1.78749431
107Visceral angiomatosis (HP:0100761)1.78587919
108Abnormality of proline metabolism (HP:0010907)1.76366058
109Hydroxyprolinuria (HP:0003080)1.76366058
110Mitral stenosis (HP:0001718)1.75865106
111Esophageal varix (HP:0002040)1.74364736
112Tibial bowing (HP:0002982)1.73401919
113Asymmetry of the thorax (HP:0001555)1.73372207
114Abnormal cartilage morphology (HP:0002763)1.73311394
115Striae distensae (HP:0001065)1.73009250
116Genu recurvatum (HP:0002816)1.72822763
117Abnormality of glutamine family amino acid metabolism (HP:0010902)1.72733095
118Hemangiomatosis (HP:0007461)1.72532722
119Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.72523689
120Bowed forearm bones (HP:0003956)1.72367012
121Bowing of the arm (HP:0006488)1.72367012
122Cupped ribs (HP:0000887)1.71809549
123Blue sclerae (HP:0000592)1.70617525
124Malignant gastrointestinal tract tumors (HP:0006749)1.70453711
125Gastrointestinal carcinoma (HP:0002672)1.70453711
126Breech presentation (HP:0001623)1.69664845
127Joint laxity (HP:0001388)1.69056359
128Congenital glaucoma (HP:0001087)1.68788295
129Soft skin (HP:0000977)1.68360877
130Abnormality of the gastric mucosa (HP:0004295)1.68219669
131Turricephaly (HP:0000262)1.67669435
132Arnold-Chiari malformation (HP:0002308)1.67662479
133Hepatocellular carcinoma (HP:0001402)1.67542428
134Chondrocalcinosis (HP:0000934)1.67435917
135Vascular calcification (HP:0004934)1.66712653
136Long toe (HP:0010511)1.65639453
137Complement deficiency (HP:0004431)1.64520775
138Relative macrocephaly (HP:0004482)1.64320726
139Vertebral clefting (HP:0008428)1.63728443
140Germ cell neoplasia (HP:0100728)1.61719425
141Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.61207957
142Abnormal delivery (HP:0001787)1.61094947
143Natal tooth (HP:0000695)1.60218404
144Mildly elevated creatine phosphokinase (HP:0008180)1.60039908
145Abnormality of monocarboxylic acid metabolism (HP:0010996)1.58926432
146Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.58165382
147Abnormality of Sharpey fibers (HP:0100685)1.57671670
148Deviation of the thumb (HP:0009603)1.56475199
149Cubitus valgus (HP:0002967)1.55672237
150Biliary tract neoplasm (HP:0100574)1.55436004
151Conjugated hyperbilirubinemia (HP:0002908)1.54588958
152Coronal craniosynostosis (HP:0004440)1.53941161
153Mitral regurgitation (HP:0001653)1.52971903
154Hyperacusis (HP:0010780)1.52533944
155Broad face (HP:0000283)1.51287109
156Spinal rigidity (HP:0003306)1.51218593
157Disproportionate tall stature (HP:0001519)1.51125665
158Abnormality of the phalanges of the hallux (HP:0010057)1.50831110
159Cerebral inclusion bodies (HP:0100314)1.50769488

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.54284506
2TRIB33.93790453
3PKN23.54351810
4SCYL22.97743512
5LATS12.90316899
6CDK122.86750860
7LATS22.84563537
8PTK62.61040630
9EEF2K2.37096353
10PDGFRA2.29648800
11ERN12.29285409
12MAP3K22.28282197
13TTN2.24388247
14SIK12.23323975
15RIPK12.19924444
16DDR22.07099770
17TAOK32.05518177
18LRRK21.92699274
19FGFR21.82268964
20STK241.76335999
21SMG11.75156278
22ICK1.70558525
23LMTK21.63603046
24MST41.60455411
25BRD41.55779473
26STK391.52648931
27STK38L1.50101701
28EPHB11.49053383
29MST1R1.48888594
30MET1.42644126
31FER1.41710411
32TGFBR21.38002392
33PRPF4B1.37396302
34AKT31.36355494
35RET1.35707774
36PDGFRB1.31978487
37MAP3K101.23621191
38FGFR31.19610752
39PTK21.16057919
40PAK21.16020639
41TSSK61.14548513
42TRPM71.13366831
43NEK91.12312241
44CDK61.11389123
45STK101.11285640
46IRAK31.10348237
47STK31.07475226
48TTK1.07179990
49NUAK11.06438667
50FGFR41.04626746
51EPHB21.02623375
52FLT31.02437714
53YES11.02163974
54MAP3K31.00123529
55JAK10.97650051
56EIF2AK30.94735109
57MAP3K140.93704335
58WNK40.91667569
59INSRR0.90344073
60BMX0.89907540
61CAMK1D0.89739588
62PAK30.89486472
63EIF2AK10.89242799
64TAF10.87652321
65KSR20.85519898
66CAMKK10.85386398
67NTRK10.82979377
68JAK20.82973847
69PIK3CA0.81267530
70DMPK0.80967599
71PBK0.78603861
72PRKCH0.76791394
73MAP3K120.76287905
74PNCK0.75236605
75JAK30.74825976
76MKNK10.74642674
77MAP3K130.74582627
78MYLK0.73797070
79PAK40.73730677
80FGFR10.73572328
81ERBB30.73154006
82DYRK1B0.71683199
83HIPK20.71605897
84KSR10.70667465
85MKNK20.70008931
86CAMK1G0.69523772
87MAP3K60.69119304
88ITK0.68713783
89PASK0.66093965
90CAMKK20.63728575
91BCKDK0.63164773
92TESK10.62988258
93BRSK20.62280205
94EPHA30.62225381
95GSK3A0.61884630
96EPHA20.59355374
97PRKG20.58112207
98MTOR0.57981445
99PRKD10.57640457
100MAP3K90.57429935
101MOS0.56315720
102MAP3K70.55749984
103SGK30.55055703
104EGFR0.54815799
105ROCK20.53898367
106MAP3K80.53141666
107TGFBR10.51892507
108NEK60.51663275
109CSF1R0.51647352
110MAP2K30.51182800
111RPS6KB20.50623674
112MAP2K10.49801413
113SRPK10.48312107
114CSK0.47331049
115ALK0.46907514
116ERBB40.46897673
117WNK10.46539240
118PDPK10.46496576
119IGF1R0.45703674
120INSR0.45515233
121CDC42BPA0.45389248
122OXSR10.44846187
123PIK3CG0.44782149
124BCR0.44589542
125CDK70.44043374
126NLK0.44027661
127PDK10.43452671
128MAP3K10.43277460
129ROCK10.42205272
130TYRO30.42182250
131STK380.41671704
132MAP2K20.41419425
133RPS6KA40.40575288
134LIMK10.40122906
135MELK0.39858371
136CDK90.39845946
137CSNK1A1L0.39724639
138ILK0.38252650
139PDK20.37965041
140ERBB20.37764968
141TYK20.37537380
142FYN0.37145893
143CLK10.36652986
144NEK20.36363243
145ARAF0.34576829
146RPS6KB10.34466009

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.32991649
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.73451810
3Sulfur metabolism_Homo sapiens_hsa009202.64990452
4Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.47229951
5ECM-receptor interaction_Homo sapiens_hsa045121.83374653
6Maturity onset diabetes of the young_Homo sapiens_hsa049501.82049631
7Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.72035880
8Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.67985465
9Focal adhesion_Homo sapiens_hsa045101.65331975
10Protein digestion and absorption_Homo sapiens_hsa049741.49704447
11N-Glycan biosynthesis_Homo sapiens_hsa005101.47402241
12Amoebiasis_Homo sapiens_hsa051461.26880228
13Caffeine metabolism_Homo sapiens_hsa002321.26462048
14Proteoglycans in cancer_Homo sapiens_hsa052051.25317096
15Fatty acid degradation_Homo sapiens_hsa000711.24664023
16Adherens junction_Homo sapiens_hsa045201.23962809
17Small cell lung cancer_Homo sapiens_hsa052221.23830845
18Leukocyte transendothelial migration_Homo sapiens_hsa046701.23143987
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.23007852
20Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.20945105
21Cyanoamino acid metabolism_Homo sapiens_hsa004601.20740496
22Bile secretion_Homo sapiens_hsa049761.19620616
23Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.19481419
24Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.19186795
25Chronic myeloid leukemia_Homo sapiens_hsa052201.18010725
26Arginine biosynthesis_Homo sapiens_hsa002201.17605142
27Insulin resistance_Homo sapiens_hsa049311.14972264
28Primary bile acid biosynthesis_Homo sapiens_hsa001201.14434334
29Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.14394370
30Other glycan degradation_Homo sapiens_hsa005111.13023067
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.09396777
32Vitamin digestion and absorption_Homo sapiens_hsa049771.08374688
33Renin-angiotensin system_Homo sapiens_hsa046141.07224780
34Fat digestion and absorption_Homo sapiens_hsa049751.06995190
35Carbohydrate digestion and absorption_Homo sapiens_hsa049731.06507587
36Pentose and glucuronate interconversions_Homo sapiens_hsa000401.06245063
37Pancreatic cancer_Homo sapiens_hsa052121.06169000
38Thyroid hormone synthesis_Homo sapiens_hsa049181.06056394
39Selenocompound metabolism_Homo sapiens_hsa004501.04634497
40PPAR signaling pathway_Homo sapiens_hsa033201.03805781
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.03801610
42Bladder cancer_Homo sapiens_hsa052191.00578810
43Platelet activation_Homo sapiens_hsa046110.98272999
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.97060311
45Tryptophan metabolism_Homo sapiens_hsa003800.97004747
46Sphingolipid metabolism_Homo sapiens_hsa006000.96078754
47Lysosome_Homo sapiens_hsa041420.95244435
48Starch and sucrose metabolism_Homo sapiens_hsa005000.94849650
49Colorectal cancer_Homo sapiens_hsa052100.94634171
50Thyroid hormone signaling pathway_Homo sapiens_hsa049190.93584667
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.93241521
52Complement and coagulation cascades_Homo sapiens_hsa046100.91810194
53Prostate cancer_Homo sapiens_hsa052150.91247171
54Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89497999
55ErbB signaling pathway_Homo sapiens_hsa040120.88951010
56Endometrial cancer_Homo sapiens_hsa052130.88153745
57Pancreatic secretion_Homo sapiens_hsa049720.87640648
58mTOR signaling pathway_Homo sapiens_hsa041500.87345570
59Fatty acid metabolism_Homo sapiens_hsa012120.85863212
60Tight junction_Homo sapiens_hsa045300.84504164
61Toxoplasmosis_Homo sapiens_hsa051450.82422171
62Glioma_Homo sapiens_hsa052140.82400429
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.81933432
64Protein export_Homo sapiens_hsa030600.78721059
65ABC transporters_Homo sapiens_hsa020100.77478319
66Galactose metabolism_Homo sapiens_hsa000520.77212908
67Propanoate metabolism_Homo sapiens_hsa006400.77051764
68Adipocytokine signaling pathway_Homo sapiens_hsa049200.76466697
69Fatty acid biosynthesis_Homo sapiens_hsa000610.75846195
70Pathways in cancer_Homo sapiens_hsa052000.75518105
71Acute myeloid leukemia_Homo sapiens_hsa052210.73827201
72Glycosaminoglycan degradation_Homo sapiens_hsa005310.73652321
73Renal cell carcinoma_Homo sapiens_hsa052110.72796464
74Choline metabolism in cancer_Homo sapiens_hsa052310.71004388
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70719391
76Estrogen signaling pathway_Homo sapiens_hsa049150.69390119
77Non-small cell lung cancer_Homo sapiens_hsa052230.69043008
78Lysine degradation_Homo sapiens_hsa003100.68210266
79Histidine metabolism_Homo sapiens_hsa003400.67760446
80Fructose and mannose metabolism_Homo sapiens_hsa000510.66525123
81Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66477565
82AMPK signaling pathway_Homo sapiens_hsa041520.66350748
83Type II diabetes mellitus_Homo sapiens_hsa049300.66000334
84Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.65558815
85Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64074653
86Melanoma_Homo sapiens_hsa052180.63866175
87Phosphatidylinositol signaling system_Homo sapiens_hsa040700.62361559
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61748603
89VEGF signaling pathway_Homo sapiens_hsa043700.60846084
90GnRH signaling pathway_Homo sapiens_hsa049120.59670542
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.59565895
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.58757543
93Prolactin signaling pathway_Homo sapiens_hsa049170.58666634
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58099416
95Butanoate metabolism_Homo sapiens_hsa006500.57936144
96mRNA surveillance pathway_Homo sapiens_hsa030150.57364124
97Dorso-ventral axis formation_Homo sapiens_hsa043200.57119538
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56761648
99Endocytosis_Homo sapiens_hsa041440.56700601
100Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56446192
101Notch signaling pathway_Homo sapiens_hsa043300.56439912
102Antigen processing and presentation_Homo sapiens_hsa046120.56328310
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55518428
104FoxO signaling pathway_Homo sapiens_hsa040680.55179985
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.54701300
106Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54405355
107MicroRNAs in cancer_Homo sapiens_hsa052060.54240558
108Hepatitis C_Homo sapiens_hsa051600.53301185
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.53284288
110Thyroid cancer_Homo sapiens_hsa052160.52926085
111PI3K-Akt signaling pathway_Homo sapiens_hsa041510.52038396
112Mineral absorption_Homo sapiens_hsa049780.50842080
113HIF-1 signaling pathway_Homo sapiens_hsa040660.50620411
114Shigellosis_Homo sapiens_hsa051310.49949674
115Gap junction_Homo sapiens_hsa045400.49682989
116Glycerolipid metabolism_Homo sapiens_hsa005610.49666922
117Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49656936
118Phospholipase D signaling pathway_Homo sapiens_hsa040720.49200159
119Gastric acid secretion_Homo sapiens_hsa049710.49118374
120Wnt signaling pathway_Homo sapiens_hsa043100.48882541
121TGF-beta signaling pathway_Homo sapiens_hsa043500.48225372
122Insulin signaling pathway_Homo sapiens_hsa049100.48196898
123Dilated cardiomyopathy_Homo sapiens_hsa054140.47704605
124Long-term potentiation_Homo sapiens_hsa047200.47572435
125Staphylococcus aureus infection_Homo sapiens_hsa051500.46974442
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.46894060
127Hippo signaling pathway_Homo sapiens_hsa043900.45298127
128Vibrio cholerae infection_Homo sapiens_hsa051100.44944555
129B cell receptor signaling pathway_Homo sapiens_hsa046620.43328873
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.43285037
131Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.42441090
132Osteoclast differentiation_Homo sapiens_hsa043800.42305826
133Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41973106
134Rap1 signaling pathway_Homo sapiens_hsa040150.40958589
135Renin secretion_Homo sapiens_hsa049240.39843417
136Prion diseases_Homo sapiens_hsa050200.39674517
137Inositol phosphate metabolism_Homo sapiens_hsa005620.39549199

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