

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | kynurenine metabolic process (GO:0070189) | 7.72899847 |
| 2 | indole-containing compound catabolic process (GO:0042436) | 7.25112370 |
| 3 | indolalkylamine catabolic process (GO:0046218) | 7.25112370 |
| 4 | tryptophan catabolic process (GO:0006569) | 7.25112370 |
| 5 | tryptophan metabolic process (GO:0006568) | 6.79045862 |
| 6 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 5.97560633 |
| 7 | cell wall macromolecule catabolic process (GO:0016998) | 5.64052757 |
| 8 | positive regulation of T cell differentiation in thymus (GO:0033089) | 5.61597177 |
| 9 | DNA deamination (GO:0045006) | 5.54287401 |
| 10 | indolalkylamine metabolic process (GO:0006586) | 5.19464132 |
| 11 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 4.85826773 |
| 12 | cytochrome complex assembly (GO:0017004) | 4.69512486 |
| 13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.69052965 |
| 14 | cell wall macromolecule metabolic process (GO:0044036) | 4.68617406 |
| 15 | preassembly of GPI anchor in ER membrane (GO:0016254) | 4.68522709 |
| 16 | adaptation of signaling pathway (GO:0023058) | 4.66542321 |
| 17 | regulation of regulatory T cell differentiation (GO:0045589) | 4.60087067 |
| 18 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.49658737 |
| 19 | protein polyglutamylation (GO:0018095) | 4.47314569 |
| 20 | histone H2A ubiquitination (GO:0033522) | 4.38057530 |
| 21 | regulation of memory T cell differentiation (GO:0043380) | 4.35987743 |
| 22 | respiratory chain complex IV assembly (GO:0008535) | 4.31427889 |
| 23 | cellular biogenic amine catabolic process (GO:0042402) | 4.22993372 |
| 24 | amine catabolic process (GO:0009310) | 4.22993372 |
| 25 | cytidine deamination (GO:0009972) | 4.07587061 |
| 26 | cytidine metabolic process (GO:0046087) | 4.07587061 |
| 27 | cytidine catabolic process (GO:0006216) | 4.07587061 |
| 28 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 4.06518163 |
| 29 | isotype switching (GO:0045190) | 4.06518163 |
| 30 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 4.06518163 |
| 31 | regulation of T cell differentiation in thymus (GO:0033081) | 4.00879187 |
| 32 | NAD biosynthetic process (GO:0009435) | 3.96115300 |
| 33 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.91157100 |
| 34 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.91157100 |
| 35 | indole-containing compound metabolic process (GO:0042430) | 3.85575499 |
| 36 | regulation of immunoglobulin secretion (GO:0051023) | 3.82776868 |
| 37 | kidney morphogenesis (GO:0060993) | 3.81277510 |
| 38 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.80502199 |
| 39 | DNA double-strand break processing (GO:0000729) | 3.79326208 |
| 40 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.75412651 |
| 41 | cullin deneddylation (GO:0010388) | 3.73747966 |
| 42 | snRNA transcription (GO:0009301) | 3.72731258 |
| 43 | maturation of 5.8S rRNA (GO:0000460) | 3.71934645 |
| 44 | positive regulation of T cell cytokine production (GO:0002726) | 3.71211401 |
| 45 | benzene-containing compound metabolic process (GO:0042537) | 3.64982608 |
| 46 | DNA demethylation (GO:0080111) | 3.59692944 |
| 47 | non-recombinational repair (GO:0000726) | 3.58558466 |
| 48 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.58558466 |
| 49 | aromatic amino acid family catabolic process (GO:0009074) | 3.50558174 |
| 50 | iron ion import (GO:0097286) | 3.48178410 |
| 51 | pseudouridine synthesis (GO:0001522) | 3.46848659 |
| 52 | protein complex biogenesis (GO:0070271) | 3.45892885 |
| 53 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.41307942 |
| 54 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.39936219 |
| 55 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.39697388 |
| 56 | oxidative phosphorylation (GO:0006119) | 3.38260234 |
| 57 | negative regulation of T cell mediated immunity (GO:0002710) | 3.35595132 |
| 58 | protein deneddylation (GO:0000338) | 3.35439481 |
| 59 | cellular response to interferon-beta (GO:0035458) | 3.34172472 |
| 60 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.32583150 |
| 61 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.32583150 |
| 62 | GPI anchor metabolic process (GO:0006505) | 3.27975000 |
| 63 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.27770914 |
| 64 | positive regulation of DNA repair (GO:0045739) | 3.24374939 |
| 65 | interferon-gamma production (GO:0032609) | 3.24154125 |
| 66 | piRNA metabolic process (GO:0034587) | 3.23405664 |
| 67 | response to gravity (GO:0009629) | 3.17617179 |
| 68 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.17543716 |
| 69 | copper ion transport (GO:0006825) | 3.11678836 |
| 70 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.09809269 |
| 71 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.03605082 |
| 72 | negative regulation of T cell differentiation (GO:0045581) | 2.99562184 |
| 73 | GPI anchor biosynthetic process (GO:0006506) | 2.99233845 |
| 74 | ovulation cycle (GO:0042698) | 2.97134751 |
| 75 | response to interferon-beta (GO:0035456) | 2.97020992 |
| 76 | pyridine nucleotide biosynthetic process (GO:0019363) | 2.94453982 |
| 77 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 2.94453982 |
| 78 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.93028445 |
| 79 | response to growth hormone (GO:0060416) | 2.91967131 |
| 80 | negative T cell selection (GO:0043383) | 2.91091516 |
| 81 | histone H2A monoubiquitination (GO:0035518) | 2.90602364 |
| 82 | negative regulation of mRNA processing (GO:0050686) | 2.90139245 |
| 83 | synapsis (GO:0007129) | 2.89309170 |
| 84 | regulation of T cell cytokine production (GO:0002724) | 2.88041597 |
| 85 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.87797908 |
| 86 | positive T cell selection (GO:0043368) | 2.83776158 |
| 87 | B cell activation involved in immune response (GO:0002312) | 2.81543546 |
| 88 | regulation of thymocyte apoptotic process (GO:0070243) | 2.80343373 |
| 89 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.80044817 |
| 90 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.80044817 |
| 91 | NADH dehydrogenase complex assembly (GO:0010257) | 2.80044817 |
| 92 | aromatic amino acid family metabolic process (GO:0009072) | 2.79466567 |
| 93 | lysine catabolic process (GO:0006554) | 2.76912435 |
| 94 | lysine metabolic process (GO:0006553) | 2.76912435 |
| 95 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.73626812 |
| 96 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.70324446 |
| 97 | maturation of SSU-rRNA (GO:0030490) | 2.68393952 |
| 98 | replication fork processing (GO:0031297) | 2.67592892 |
| 99 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.67537353 |
| 100 | somite development (GO:0061053) | 2.67279439 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.12647541 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.29969314 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.18063511 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.13229031 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.03704601 |
| 6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.03315633 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.03116954 |
| 8 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.69612674 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.40072263 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.30083771 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.23248503 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.16901746 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.16262765 |
| 14 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.11596917 |
| 15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.10709334 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.08338811 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.06104813 |
| 18 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.05478151 |
| 19 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 2.04832655 |
| 20 | CBP_20019798_ChIP-Seq_JUKART_Human | 2.04832655 |
| 21 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.02395346 |
| 22 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.01717733 |
| 23 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.00612660 |
| 24 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.93489984 |
| 25 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.91185612 |
| 26 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.83116778 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.82013903 |
| 28 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.79910700 |
| 29 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.78646303 |
| 30 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.70013935 |
| 31 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.68672313 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.68321162 |
| 33 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.66166883 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.65908233 |
| 35 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.65574279 |
| 36 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.64447905 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.56373798 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.56373798 |
| 39 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.55450412 |
| 40 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.54751298 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.50503024 |
| 42 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.49895103 |
| 43 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.49412650 |
| 44 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.48716002 |
| 45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.47243640 |
| 46 | AR_20517297_ChIP-Seq_VCAP_Human | 1.47236054 |
| 47 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.46691889 |
| 48 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.45023672 |
| 49 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.39971423 |
| 50 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.39695384 |
| 51 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.38845997 |
| 52 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.33719863 |
| 53 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32657291 |
| 54 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.32059838 |
| 55 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.30069150 |
| 56 | P300_19829295_ChIP-Seq_ESCs_Human | 1.29701853 |
| 57 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.28904266 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.25725236 |
| 59 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.21331176 |
| 60 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21253776 |
| 61 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.18506925 |
| 62 | GATA3_26560356_Chip-Seq_TH2_Human | 1.17610441 |
| 63 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17475798 |
| 64 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.15228782 |
| 65 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.13759220 |
| 66 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.12626661 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.12345690 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.12345690 |
| 69 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12095054 |
| 70 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.11876847 |
| 71 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.10588386 |
| 72 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10271953 |
| 73 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.06477729 |
| 74 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.05637902 |
| 75 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.04346686 |
| 76 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04206272 |
| 77 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.03149287 |
| 78 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.02591018 |
| 79 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.01889169 |
| 80 | GATA3_26560356_Chip-Seq_TH1_Human | 1.00707111 |
| 81 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.00389058 |
| 82 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.00116141 |
| 83 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.00005644 |
| 84 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.99021502 |
| 85 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98953994 |
| 86 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98741688 |
| 87 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.98406463 |
| 88 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.97800802 |
| 89 | MYB_26560356_Chip-Seq_TH2_Human | 0.97613514 |
| 90 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.96875512 |
| 91 | AR_25329375_ChIP-Seq_VCAP_Human | 0.96870329 |
| 92 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.96258929 |
| 93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94282534 |
| 94 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.93936231 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.93457580 |
| 96 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.92464017 |
| 97 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.92460176 |
| 98 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.92170272 |
| 99 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.91199411 |
| 100 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.90319113 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 5.31626179 |
| 2 | MP0008875_abnormal_xenobiotic_pharmacok | 4.75905446 |
| 3 | MP0001853_heart_inflammation | 3.06948816 |
| 4 | MP0006054_spinal_hemorrhage | 3.02501159 |
| 5 | MP0005671_abnormal_response_to | 2.82665205 |
| 6 | MP0003646_muscle_fatigue | 2.70047406 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.51220535 |
| 8 | MP0001986_abnormal_taste_sensitivity | 2.47787278 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.38305490 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.33643329 |
| 11 | MP0002837_dystrophic_cardiac_calcinosis | 2.24966113 |
| 12 | MP0003252_abnormal_bile_duct | 2.24844352 |
| 13 | MP0003806_abnormal_nucleotide_metabolis | 2.24521564 |
| 14 | MP0005167_abnormal_blood-brain_barrier | 2.12618437 |
| 15 | MP0003866_abnormal_defecation | 2.09409049 |
| 16 | MP0008058_abnormal_DNA_repair | 2.04697319 |
| 17 | MP0005423_abnormal_somatic_nervous | 2.04455998 |
| 18 | MP0002653_abnormal_ependyma_morphology | 2.01974170 |
| 19 | MP0009053_abnormal_anal_canal | 1.99552653 |
| 20 | MP0009780_abnormal_chondrocyte_physiolo | 1.95966707 |
| 21 | MP0010094_abnormal_chromosome_stability | 1.93173759 |
| 22 | MP0002006_tumorigenesis | 1.81651805 |
| 23 | MP0008789_abnormal_olfactory_epithelium | 1.77279672 |
| 24 | MP0008775_abnormal_heart_ventricle | 1.74291077 |
| 25 | MP0004145_abnormal_muscle_electrophysio | 1.73972906 |
| 26 | MP0006292_abnormal_olfactory_placode | 1.72819998 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 1.66714188 |
| 28 | MP0003763_abnormal_thymus_physiology | 1.66381081 |
| 29 | MP0003656_abnormal_erythrocyte_physiolo | 1.65597905 |
| 30 | MP0003011_delayed_dark_adaptation | 1.65521403 |
| 31 | MP0003718_maternal_effect | 1.57271668 |
| 32 | MP0005360_urolithiasis | 1.52109172 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.51261842 |
| 34 | MP0002166_altered_tumor_susceptibility | 1.51024287 |
| 35 | MP0001542_abnormal_bone_strength | 1.49980890 |
| 36 | MP0000537_abnormal_urethra_morphology | 1.45801544 |
| 37 | MP0005253_abnormal_eye_physiology | 1.43526980 |
| 38 | MP0005000_abnormal_immune_tolerance | 1.37011217 |
| 39 | MP0004381_abnormal_hair_follicle | 1.34674344 |
| 40 | MP0005636_abnormal_mineral_homeostasis | 1.32957020 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.31600739 |
| 42 | MP0003186_abnormal_redox_activity | 1.26096561 |
| 43 | MP0009785_altered_susceptibility_to | 1.23130411 |
| 44 | MP0009764_decreased_sensitivity_to | 1.22935300 |
| 45 | MP0001984_abnormal_olfaction | 1.21231869 |
| 46 | MP0010329_abnormal_lipoprotein_level | 1.15558472 |
| 47 | MP0008872_abnormal_physiological_respon | 1.11577893 |
| 48 | MP0002452_abnormal_antigen_presenting | 1.09429064 |
| 49 | MP0002736_abnormal_nociception_after | 1.07906426 |
| 50 | MP0004215_abnormal_myocardial_fiber | 1.07857233 |
| 51 | MP0000372_irregular_coat_pigmentation | 1.06397772 |
| 52 | MP0005394_taste/olfaction_phenotype | 1.04783575 |
| 53 | MP0005499_abnormal_olfactory_system | 1.04783575 |
| 54 | MP0000427_abnormal_hair_cycle | 1.03267485 |
| 55 | MP0001800_abnormal_humoral_immune | 1.02277322 |
| 56 | MP0004947_skin_inflammation | 1.00372033 |
| 57 | MP0002723_abnormal_immune_serum | 1.00094359 |
| 58 | MP0004185_abnormal_adipocyte_glucose | 0.97804789 |
| 59 | MP0001819_abnormal_immune_cell | 0.95488123 |
| 60 | MP0002277_abnormal_respiratory_mucosa | 0.94432509 |
| 61 | MP0002234_abnormal_pharynx_morphology | 0.93749053 |
| 62 | MP0004782_abnormal_surfactant_physiolog | 0.93487277 |
| 63 | MP0000689_abnormal_spleen_morphology | 0.92682360 |
| 64 | MP0005647_abnormal_sex_gland | 0.91897038 |
| 65 | MP0005220_abnormal_exocrine_pancreas | 0.91537778 |
| 66 | MP0002420_abnormal_adaptive_immunity | 0.91128823 |
| 67 | MP0005085_abnormal_gallbladder_physiolo | 0.90880373 |
| 68 | MP0002127_abnormal_cardiovascular_syste | 0.90845176 |
| 69 | MP0010155_abnormal_intestine_physiology | 0.89114584 |
| 70 | MP0002398_abnormal_bone_marrow | 0.87537426 |
| 71 | MP0002638_abnormal_pupillary_reflex | 0.85844020 |
| 72 | MP0003045_fibrosis | 0.85651799 |
| 73 | MP0009765_abnormal_xenobiotic_induced | 0.80944667 |
| 74 | MP0000685_abnormal_immune_system | 0.76879139 |
| 75 | MP0000383_abnormal_hair_follicle | 0.76388647 |
| 76 | MP0002876_abnormal_thyroid_physiology | 0.75473224 |
| 77 | MP0002928_abnormal_bile_duct | 0.74365932 |
| 78 | MP0001765_abnormal_ion_homeostasis | 0.73960830 |
| 79 | MP0005332_abnormal_amino_acid | 0.72968550 |
| 80 | MP0002693_abnormal_pancreas_physiology | 0.72102074 |
| 81 | MP0002102_abnormal_ear_morphology | 0.70379495 |
| 82 | MP0004142_abnormal_muscle_tone | 0.69660817 |
| 83 | MP0000230_abnormal_systemic_arterial | 0.66344033 |
| 84 | MP0001501_abnormal_sleep_pattern | 0.65992042 |
| 85 | MP0010678_abnormal_skin_adnexa | 0.65346981 |
| 86 | MP0001486_abnormal_startle_reflex | 0.65323957 |
| 87 | MP0005389_reproductive_system_phenotype | 0.63668429 |
| 88 | MP0005084_abnormal_gallbladder_morpholo | 0.63582426 |
| 89 | MP0001968_abnormal_touch/_nociception | 0.62198700 |
| 90 | MP0002419_abnormal_innate_immunity | 0.61453096 |
| 91 | MP0000703_abnormal_thymus_morphology | 0.61185240 |
| 92 | MP0004085_abnormal_heartbeat | 0.60146901 |
| 93 | MP0000716_abnormal_immune_system | 0.60109725 |
| 94 | MP0003868_abnormal_feces_composition | 0.58319988 |
| 95 | MP0005171_absent_coat_pigmentation | 0.57651773 |
| 96 | MP0005645_abnormal_hypothalamus_physiol | 0.57627775 |
| 97 | MP0002138_abnormal_hepatobiliary_system | 0.56901362 |
| 98 | MP0000631_abnormal_neuroendocrine_gland | 0.55884301 |
| 99 | MP0001845_abnormal_inflammatory_respons | 0.55200926 |
| 100 | MP0001790_abnormal_immune_system | 0.54969274 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.09368094 |
| 2 | Methylmalonic acidemia (HP:0002912) | 4.78446449 |
| 3 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.81100034 |
| 4 | Pancreatic cysts (HP:0001737) | 3.66828846 |
| 5 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.65908198 |
| 6 | Abnormality of alanine metabolism (HP:0010916) | 3.65908198 |
| 7 | Hyperalaninemia (HP:0003348) | 3.65908198 |
| 8 | Methylmalonic aciduria (HP:0012120) | 3.50343172 |
| 9 | Aplastic anemia (HP:0001915) | 3.24067700 |
| 10 | Severe combined immunodeficiency (HP:0004430) | 3.23289171 |
| 11 | True hermaphroditism (HP:0010459) | 3.15531847 |
| 12 | Duplicated collecting system (HP:0000081) | 3.14297229 |
| 13 | Adactyly (HP:0009776) | 3.10896475 |
| 14 | Abnormality of the middle phalanges of the toes (HP:0010183) | 3.08755150 |
| 15 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 3.07519083 |
| 16 | Abnormality of the renal collecting system (HP:0004742) | 3.07054751 |
| 17 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.05177562 |
| 18 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 3.05084121 |
| 19 | Fibular aplasia (HP:0002990) | 3.00180702 |
| 20 | Clubbing of toes (HP:0100760) | 2.99557674 |
| 21 | Abnormality of the ileum (HP:0001549) | 2.91332611 |
| 22 | Thyroiditis (HP:0100646) | 2.86053859 |
| 23 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.85224030 |
| 24 | Abnormality of vitamin B metabolism (HP:0004340) | 2.83826643 |
| 25 | Meckel diverticulum (HP:0002245) | 2.81042593 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.80393387 |
| 27 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.76393162 |
| 28 | Renal cortical cysts (HP:0000803) | 2.74266790 |
| 29 | Hemiparesis (HP:0001269) | 2.71578213 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.70138158 |
| 31 | Lipid accumulation in hepatocytes (HP:0006561) | 2.66422021 |
| 32 | Increased serum lactate (HP:0002151) | 2.65947842 |
| 33 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.64814945 |
| 34 | Large for gestational age (HP:0001520) | 2.62747899 |
| 35 | Hyperglycinuria (HP:0003108) | 2.61923403 |
| 36 | Hepatocellular necrosis (HP:0001404) | 2.61874203 |
| 37 | Combined immunodeficiency (HP:0005387) | 2.58274382 |
| 38 | Hypoplasia of the uterus (HP:0000013) | 2.56978175 |
| 39 | Mitochondrial inheritance (HP:0001427) | 2.56742275 |
| 40 | Testicular atrophy (HP:0000029) | 2.51991119 |
| 41 | Abnormality of the carotid arteries (HP:0005344) | 2.51279490 |
| 42 | Hepatic necrosis (HP:0002605) | 2.47065864 |
| 43 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.42586240 |
| 44 | Pigmentary retinal degeneration (HP:0001146) | 2.41891213 |
| 45 | IgG deficiency (HP:0004315) | 2.40119048 |
| 46 | Increased CSF lactate (HP:0002490) | 2.39492710 |
| 47 | Nephronophthisis (HP:0000090) | 2.35998388 |
| 48 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.35105671 |
| 49 | Poor head control (HP:0002421) | 2.25050097 |
| 50 | Anomalous pulmonary venous return (HP:0010772) | 2.23298577 |
| 51 | Abnormality of the preputium (HP:0100587) | 2.22860553 |
| 52 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.21977883 |
| 53 | Spastic paraparesis (HP:0002313) | 2.19360203 |
| 54 | Short hallux (HP:0010109) | 2.18089685 |
| 55 | Pheochromocytoma (HP:0002666) | 2.15227067 |
| 56 | Tubulointerstitial fibrosis (HP:0005576) | 2.13835833 |
| 57 | Abnormality of glycine metabolism (HP:0010895) | 2.12225205 |
| 58 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.12225205 |
| 59 | Porencephaly (HP:0002132) | 2.11447540 |
| 60 | Cleft eyelid (HP:0000625) | 2.10784716 |
| 61 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.10090401 |
| 62 | Cystic liver disease (HP:0006706) | 2.06997950 |
| 63 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.05883460 |
| 64 | Abnormality of the renal cortex (HP:0011035) | 2.03738253 |
| 65 | Renal Fanconi syndrome (HP:0001994) | 2.03287544 |
| 66 | Tetraparesis (HP:0002273) | 1.99543594 |
| 67 | Abnormality of vitamin metabolism (HP:0100508) | 1.99227858 |
| 68 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.98038475 |
| 69 | Petechiae (HP:0000967) | 1.97586770 |
| 70 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.95998487 |
| 71 | Progressive microcephaly (HP:0000253) | 1.95944756 |
| 72 | Posterior subcapsular cataract (HP:0007787) | 1.94197466 |
| 73 | Prolonged neonatal jaundice (HP:0006579) | 1.94117546 |
| 74 | Neuroendocrine neoplasm (HP:0100634) | 1.92311722 |
| 75 | Increased intramyocellular lipid droplets (HP:0012240) | 1.92201413 |
| 76 | Neurodegeneration (HP:0002180) | 1.91587107 |
| 77 | Neoplasm of the adrenal gland (HP:0100631) | 1.91253981 |
| 78 | Absent/shortened dynein arms (HP:0200106) | 1.89500543 |
| 79 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.89500543 |
| 80 | Abnormality of the pulmonary veins (HP:0011718) | 1.88702325 |
| 81 | Abolished electroretinogram (ERG) (HP:0000550) | 1.87585240 |
| 82 | Exertional dyspnea (HP:0002875) | 1.86996806 |
| 83 | Stomach cancer (HP:0012126) | 1.85919865 |
| 84 | Abnormality of proline metabolism (HP:0010907) | 1.85735674 |
| 85 | Hydroxyprolinuria (HP:0003080) | 1.85735674 |
| 86 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.85676421 |
| 87 | Congenital, generalized hypertrichosis (HP:0004540) | 1.84957390 |
| 88 | Dysdiadochokinesis (HP:0002075) | 1.83641486 |
| 89 | Abnormality of chromosome stability (HP:0003220) | 1.82750260 |
| 90 | Ketoacidosis (HP:0001993) | 1.82415018 |
| 91 | T lymphocytopenia (HP:0005403) | 1.80032615 |
| 92 | Acute necrotizing encephalopathy (HP:0006965) | 1.79886612 |
| 93 | Abnormality of the diencephalon (HP:0010662) | 1.78784075 |
| 94 | Abnormality of the renal medulla (HP:0100957) | 1.78601984 |
| 95 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.78050551 |
| 96 | Dicarboxylic aciduria (HP:0003215) | 1.78050551 |
| 97 | Molar tooth sign on MRI (HP:0002419) | 1.76986350 |
| 98 | Abnormality of midbrain morphology (HP:0002418) | 1.76986350 |
| 99 | Medial flaring of the eyebrow (HP:0010747) | 1.76557065 |
| 100 | Small intestinal stenosis (HP:0012848) | 1.76218724 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.59412716 |
| 2 | MST4 | 3.77902912 |
| 3 | EIF2AK1 | 3.66068191 |
| 4 | FRK | 3.36793702 |
| 5 | GRK7 | 3.33716043 |
| 6 | TGFBR2 | 2.91249450 |
| 7 | NUAK1 | 2.82644702 |
| 8 | TLK1 | 2.62552812 |
| 9 | MOS | 2.60497167 |
| 10 | ZAK | 2.60296778 |
| 11 | EIF2AK3 | 2.57450960 |
| 12 | EPHA3 | 2.47569603 |
| 13 | STK10 | 2.26039348 |
| 14 | EIF2AK2 | 2.17510989 |
| 15 | VRK2 | 1.87220882 |
| 16 | MAP4K2 | 1.77847984 |
| 17 | GRK5 | 1.67928430 |
| 18 | KIT | 1.57562465 |
| 19 | WNK3 | 1.55529923 |
| 20 | TAOK3 | 1.55351048 |
| 21 | SRPK1 | 1.36990410 |
| 22 | BMPR1B | 1.31139560 |
| 23 | BUB1 | 1.27870769 |
| 24 | ACVR1B | 1.27154302 |
| 25 | MKNK1 | 1.18410664 |
| 26 | CDK8 | 1.12057092 |
| 27 | PHKG2 | 1.10509707 |
| 28 | PHKG1 | 1.10509707 |
| 29 | KDR | 1.08215873 |
| 30 | MAP4K1 | 0.97181925 |
| 31 | GRK1 | 0.96450443 |
| 32 | TGFBR1 | 0.95789035 |
| 33 | SYK | 0.95724437 |
| 34 | ATR | 0.94811083 |
| 35 | OXSR1 | 0.92621539 |
| 36 | DAPK2 | 0.90116758 |
| 37 | RPS6KA5 | 0.83408226 |
| 38 | PIK3CA | 0.82486036 |
| 39 | NEK2 | 0.80523759 |
| 40 | JAK1 | 0.79826286 |
| 41 | NEK1 | 0.78874763 |
| 42 | CHUK | 0.74864063 |
| 43 | MKNK2 | 0.74396072 |
| 44 | PAK6 | 0.73506729 |
| 45 | ITK | 0.73428044 |
| 46 | PASK | 0.71852772 |
| 47 | JAK2 | 0.70818267 |
| 48 | ADRBK1 | 0.69787005 |
| 49 | CSF1R | 0.68388375 |
| 50 | IKBKB | 0.68102958 |
| 51 | INSRR | 0.66513864 |
| 52 | MAP3K14 | 0.66142387 |
| 53 | RPS6KA4 | 0.64619351 |
| 54 | MAPK13 | 0.63552935 |
| 55 | TEC | 0.61332606 |
| 56 | NME1 | 0.60378069 |
| 57 | TSSK6 | 0.59868458 |
| 58 | PLK3 | 0.59516077 |
| 59 | PRKCI | 0.58114364 |
| 60 | LYN | 0.56816001 |
| 61 | CDC7 | 0.53740735 |
| 62 | PRKCQ | 0.53558173 |
| 63 | STK16 | 0.53455851 |
| 64 | VRK1 | 0.53328223 |
| 65 | TESK2 | 0.53118571 |
| 66 | IGF1R | 0.52504012 |
| 67 | TIE1 | 0.52136091 |
| 68 | EPHB1 | 0.51892055 |
| 69 | ADRBK2 | 0.47100606 |
| 70 | LCK | 0.44217840 |
| 71 | FGFR2 | 0.42531005 |
| 72 | TBK1 | 0.41626953 |
| 73 | DMPK | 0.40856358 |
| 74 | FES | 0.35969663 |
| 75 | BCKDK | 0.35449032 |
| 76 | OBSCN | 0.35247102 |
| 77 | PRKCE | 0.35029729 |
| 78 | ABL1 | 0.34168453 |
| 79 | RIPK4 | 0.34116855 |
| 80 | IRAK1 | 0.33194702 |
| 81 | STK39 | 0.32246560 |
| 82 | RAF1 | 0.32109013 |
| 83 | MUSK | 0.31739615 |
| 84 | NTRK3 | 0.31109560 |
| 85 | PDK1 | 0.30045277 |
| 86 | CASK | 0.29673722 |
| 87 | ILK | 0.28417914 |
| 88 | ATM | 0.28239007 |
| 89 | NEK6 | 0.26724844 |
| 90 | DAPK1 | 0.26627690 |
| 91 | ABL2 | 0.26059480 |
| 92 | PLK1 | 0.25166315 |
| 93 | WNK4 | 0.24526845 |
| 94 | STK38L | 0.22867639 |
| 95 | HCK | 0.22736983 |
| 96 | PRKACA | 0.21752038 |
| 97 | CDK6 | 0.21613246 |
| 98 | PRKG1 | 0.20482894 |
| 99 | CSNK1A1L | 0.20412714 |
| 100 | MAPKAPK2 | 0.20311679 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.05607740 |
| 2 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.51382424 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 2.25759310 |
| 4 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.24632040 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 10.4140809 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.93574138 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.92849020 |
| 8 | Protein export_Homo sapiens_hsa03060 | 1.87024566 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 1.86390098 |
| 10 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.85923877 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.82812909 |
| 12 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.65831560 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.63340468 |
| 14 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.63078700 |
| 15 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.62290210 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.60171319 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.59063687 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.54326651 |
| 19 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.43945840 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.42430663 |
| 21 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.33554880 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.31202989 |
| 23 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.26017332 |
| 24 | Asthma_Homo sapiens_hsa05310 | 1.25861668 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.24345352 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.19460171 |
| 27 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.18454645 |
| 28 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.16537866 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.14080606 |
| 30 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.06637687 |
| 31 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.05311035 |
| 32 | Mismatch repair_Homo sapiens_hsa03430 | 1.02793862 |
| 33 | Nicotine addiction_Homo sapiens_hsa05033 | 0.99858748 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 0.91735297 |
| 35 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.90109232 |
| 36 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.88744893 |
| 37 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.88267466 |
| 38 | Olfactory transduction_Homo sapiens_hsa04740 | 0.87280719 |
| 39 | Homologous recombination_Homo sapiens_hsa03440 | 0.84797756 |
| 40 | DNA replication_Homo sapiens_hsa03030 | 0.84462788 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84064491 |
| 42 | Alzheimers disease_Homo sapiens_hsa05010 | 0.83103477 |
| 43 | Allograft rejection_Homo sapiens_hsa05330 | 0.82105748 |
| 44 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.77654891 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.76299566 |
| 46 | Ribosome_Homo sapiens_hsa03010 | 0.74984367 |
| 47 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.74878710 |
| 48 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.67137628 |
| 49 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.66757809 |
| 50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.66510212 |
| 51 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.64735934 |
| 52 | Huntingtons disease_Homo sapiens_hsa05016 | 0.61323507 |
| 53 | Taste transduction_Homo sapiens_hsa04742 | 0.60941385 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.60498975 |
| 55 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.59198019 |
| 56 | Mineral absorption_Homo sapiens_hsa04978 | 0.56689232 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.56195541 |
| 58 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.55013119 |
| 59 | Salivary secretion_Homo sapiens_hsa04970 | 0.54397047 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.53089823 |
| 61 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.52178013 |
| 62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.50951172 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47255381 |
| 64 | Lysine degradation_Homo sapiens_hsa00310 | 0.46557310 |
| 65 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.46293686 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45672384 |
| 67 | GABAergic synapse_Homo sapiens_hsa04727 | 0.43610934 |
| 68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.43155594 |
| 69 | RNA transport_Homo sapiens_hsa03013 | 0.43127455 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42262308 |
| 71 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.40825811 |
| 72 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.40224402 |
| 73 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.39735461 |
| 74 | Basal transcription factors_Homo sapiens_hsa03022 | 0.39559658 |
| 75 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.37983868 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35229095 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34260137 |
| 78 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.33845846 |
| 79 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.31113617 |
| 80 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.30772755 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.28597283 |
| 82 | Morphine addiction_Homo sapiens_hsa05032 | 0.28401606 |
| 83 | Carbon metabolism_Homo sapiens_hsa01200 | 0.27571321 |
| 84 | Legionellosis_Homo sapiens_hsa05134 | 0.27495338 |
| 85 | Malaria_Homo sapiens_hsa05144 | 0.26925090 |
| 86 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.26564627 |
| 87 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.26189141 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.24629012 |
| 89 | Renin secretion_Homo sapiens_hsa04924 | 0.24405092 |
| 90 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.23693991 |
| 91 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.23436780 |
| 92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.23356622 |
| 93 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.21916259 |
| 94 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.20709631 |
| 95 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.20354329 |
| 96 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.19970470 |
| 97 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.19092590 |
| 98 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.18614263 |
| 99 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.18223409 |
| 100 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.15285057 |

