TMCC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1superoxide anion generation (GO:0042554)4.20084902
2pyrimidine nucleobase catabolic process (GO:0006208)4.18170356
3presynaptic membrane assembly (GO:0097105)4.08988217
4presynaptic membrane organization (GO:0097090)3.80574776
5G-protein coupled receptor internalization (GO:0002031)3.75403381
6embryonic retina morphogenesis in camera-type eye (GO:0060059)3.45968625
7L-amino acid import (GO:0043092)3.34800404
8C4-dicarboxylate transport (GO:0015740)3.33334179
9nucleobase catabolic process (GO:0046113)3.24817956
10axonal fasciculation (GO:0007413)3.24764429
11positive regulation of cellular amide metabolic process (GO:0034250)3.24735071
12retinal ganglion cell axon guidance (GO:0031290)3.17266642
13ionotropic glutamate receptor signaling pathway (GO:0035235)3.13380058
14negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.11666541
15regulation of non-canonical Wnt signaling pathway (GO:2000050)3.05032613
16neuron recognition (GO:0008038)3.03973258
17dendrite morphogenesis (GO:0048813)3.00680475
18histone H3-K4 trimethylation (GO:0080182)2.96161710
19regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.95515082
20regulation of sarcomere organization (GO:0060297)2.94069761
21ganglion development (GO:0061548)2.93059438
22regulation of pigment cell differentiation (GO:0050932)2.91530333
23postsynaptic membrane organization (GO:0001941)2.90183187
24cerebral cortex radially oriented cell migration (GO:0021799)2.89317805
25startle response (GO:0001964)2.88612788
26regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.87282237
27righting reflex (GO:0060013)2.85196963
28Golgi to endosome transport (GO:0006895)2.81662067
29positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.75537091
30glutamate receptor signaling pathway (GO:0007215)2.74574465
31regulation of dendritic spine morphogenesis (GO:0061001)2.71539999
32synapse assembly (GO:0007416)2.71531817
33regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.71274508
34cyclic nucleotide catabolic process (GO:0009214)2.70733919
35glycosphingolipid biosynthetic process (GO:0006688)2.67364529
36positive regulation of neurological system process (GO:0031646)2.64628854
37cilium or flagellum-dependent cell motility (GO:0001539)2.62012344
38central nervous system projection neuron axonogenesis (GO:0021952)2.61195615
39negative regulation of potassium ion transmembrane transport (GO:1901380)2.60311379
40establishment of protein localization to Golgi (GO:0072600)2.59166442
41cAMP catabolic process (GO:0006198)2.57010800
42neuron cell-cell adhesion (GO:0007158)2.56538238
43regulation of cilium movement (GO:0003352)2.53131738
44regulation of male gonad development (GO:2000018)2.52497640
45negative regulation of synaptic transmission, GABAergic (GO:0032229)2.51882467
46positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.51325974
47vesicle transport along microtubule (GO:0047496)2.50061174
48dendritic spine morphogenesis (GO:0060997)2.49360603
49positive regulation of CREB transcription factor activity (GO:0032793)2.48465487
50membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.47236958
51auditory behavior (GO:0031223)2.47141481
52negative regulation of neurotransmitter secretion (GO:0046929)2.46997808
53central nervous system neuron axonogenesis (GO:0021955)2.46267960
54protein targeting to Golgi (GO:0000042)2.46116004
55regulation of timing of cell differentiation (GO:0048505)2.45604822
56central nervous system myelination (GO:0022010)2.44800375
57axon ensheathment in central nervous system (GO:0032291)2.44800375
58otic vesicle formation (GO:0030916)2.44247534
59response to redox state (GO:0051775)2.44180508
60cerebral cortex cell migration (GO:0021795)2.44148144
61synaptic transmission, glutamatergic (GO:0035249)2.42952730
62limb bud formation (GO:0060174)2.42541001
63long-chain fatty acid biosynthetic process (GO:0042759)2.41458716
64layer formation in cerebral cortex (GO:0021819)2.39670706
65import into cell (GO:0098657)2.39649670
66positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.39296103
67amino acid import (GO:0043090)2.38402921
68mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.37925969
69regulation of germinal center formation (GO:0002634)2.37775753
70protein polyglutamylation (GO:0018095)2.36524310
71regulation of microtubule-based movement (GO:0060632)2.35540372
72negative regulation of neurotransmitter transport (GO:0051589)2.35348751
73nonmotile primary cilium assembly (GO:0035058)2.35330778
74negative regulation of cAMP-mediated signaling (GO:0043951)2.35135317
75glycerophospholipid catabolic process (GO:0046475)2.34276866
76reflex (GO:0060004)2.33760695
77G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.33036391
78macroautophagy (GO:0016236)2.31838456
79mesenchymal cell differentiation (GO:0048762)2.31039712
80photoreceptor cell differentiation (GO:0046530)2.30636864
81eye photoreceptor cell differentiation (GO:0001754)2.30636864
82detection of other organism (GO:0098543)2.30450940
83establishment of nucleus localization (GO:0040023)2.29749709
84energy homeostasis (GO:0097009)2.29612548
85protein localization to cilium (GO:0061512)2.29353911
86oligodendrocyte differentiation (GO:0048709)2.28816237
87regulation of glutamate receptor signaling pathway (GO:1900449)2.28778256
88negative regulation of myoblast differentiation (GO:0045662)2.28697046
89retrograde transport, vesicle recycling within Golgi (GO:0000301)2.27799932
90mechanosensory behavior (GO:0007638)2.26386435
91positive regulation of action potential (GO:0045760)2.26257991
92developmental pigmentation (GO:0048066)2.24808390
93adult walking behavior (GO:0007628)2.24033164
94cranial nerve structural organization (GO:0021604)2.23929163
95centriole assembly (GO:0098534)2.23415922
96neutrophil activation (GO:0042119)2.22842200
97interkinetic nuclear migration (GO:0022027)2.22513842
98positive regulation of male gonad development (GO:2000020)2.21840190
99response to host immune response (GO:0052572)2.21309632
100response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.21309632
101negative regulation of translation, ncRNA-mediated (GO:0040033)2.21162277
102regulation of translation, ncRNA-mediated (GO:0045974)2.21162277
103negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.21162277
104low-density lipoprotein particle remodeling (GO:0034374)2.21147512
105neural tube formation (GO:0001841)2.21061463
106neuron-neuron synaptic transmission (GO:0007270)2.20274597
107mesenchymal cell differentiation involved in kidney development (GO:0072161)2.19631877
108mesenchymal cell differentiation involved in renal system development (GO:2001012)2.19631877
109positive regulation of smooth muscle cell migration (GO:0014911)2.19548363
110cranial nerve morphogenesis (GO:0021602)2.19463709
111regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.19384252
112regulation of activation of Janus kinase activity (GO:0010533)2.18609064
113regulation of dendritic spine development (GO:0060998)2.18152404
114DNA integration (GO:0015074)2.17975967
115retina layer formation (GO:0010842)2.17901170
116regulation of platelet aggregation (GO:0090330)2.17818139
117synapse organization (GO:0050808)2.17362044
118superoxide metabolic process (GO:0006801)2.17359944
119establishment of mitochondrion localization (GO:0051654)2.17214208
120nerve growth factor signaling pathway (GO:0038180)2.17106880
121negative regulation of astrocyte differentiation (GO:0048712)2.17049236
122positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.16942418
123extracellular negative regulation of signal transduction (GO:1900116)2.16571060
124extracellular regulation of signal transduction (GO:1900115)2.16571060
125organelle transport along microtubule (GO:0072384)2.16551929
126synaptic vesicle maturation (GO:0016188)2.16185202
127positive regulation of interleukin-1 beta secretion (GO:0050718)2.15936779
128protein localization to synapse (GO:0035418)2.15632154
129gamma-aminobutyric acid transport (GO:0015812)2.15464057
130heart field specification (GO:0003128)2.13735565
131secondary heart field specification (GO:0003139)2.13735565
132vocalization behavior (GO:0071625)2.12940236
133neuron remodeling (GO:0016322)2.12770568
134behavioral response to nicotine (GO:0035095)2.12646764
135protein localization to Golgi apparatus (GO:0034067)2.12252474
136detection of bacterium (GO:0016045)2.12184931
137dendrite development (GO:0016358)2.11872973
138regulation of short-term neuronal synaptic plasticity (GO:0048172)2.11664735
139response to pheromone (GO:0019236)2.11566942
140olfactory bulb development (GO:0021772)2.11566448
141neurofilament cytoskeleton organization (GO:0060052)2.10603884
142androgen biosynthetic process (GO:0006702)2.08299250
143response to auditory stimulus (GO:0010996)2.07660044
144cell proliferation in forebrain (GO:0021846)2.06638597
145specification of organ identity (GO:0010092)2.06444523
146neurotransmitter-gated ion channel clustering (GO:0072578)2.06417516
147regulation of action potential (GO:0098900)2.06207481
148regulation of development, heterochronic (GO:0040034)2.06155210
149inner ear receptor stereocilium organization (GO:0060122)2.05923022
150regulation of potassium ion transmembrane transporter activity (GO:1901016)2.04991654
151neuronal action potential propagation (GO:0019227)2.04931322
152epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.04892247
153negative regulation of stem cell proliferation (GO:2000647)2.02557484
154protein K11-linked deubiquitination (GO:0035871)2.01733268
155microglial cell activation (GO:0001774)1.99537369
156regulation of excitatory postsynaptic membrane potential (GO:0060079)1.99276662
157granulocyte activation (GO:0036230)1.98428119
158regulation of synapse assembly (GO:0051963)1.97426630
159negative regulation of osteoblast proliferation (GO:0033689)1.97415026
160positive regulation of heat generation (GO:0031652)1.97297140
161female gonad development (GO:0008585)1.97290466
162prostate gland growth (GO:0060736)1.97130529
163calcium ion import (GO:0070509)1.96990586
164cell differentiation involved in kidney development (GO:0061005)1.96931163
165spinal cord motor neuron differentiation (GO:0021522)1.96792206
166positive regulation of cardiac muscle cell differentiation (GO:2000727)1.95742062
167detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)1.95511192
168neutrophil activation involved in immune response (GO:0002283)1.95404692
169positive regulation of interleukin-1 secretion (GO:0050716)1.95125449
170germinal center formation (GO:0002467)1.95064496

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.00845703
2EZH2_22144423_ChIP-Seq_EOC_Human3.57142946
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.25505133
4RBPJ_22232070_ChIP-Seq_NCS_Mouse2.63999232
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.61835773
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.50200310
7PCGF2_27294783_Chip-Seq_ESCs_Mouse2.25389603
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.09735692
9CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.07889940
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.06052369
11SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.03576355
12SUZ12_27294783_Chip-Seq_NPCs_Mouse2.02592812
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02345601
14SMAD_19615063_ChIP-ChIP_OVARY_Human2.00936527
15IGF1R_20145208_ChIP-Seq_DFB_Human1.95250846
16JARID2_20064375_ChIP-Seq_MESCs_Mouse1.94153848
17PCGF2_27294783_Chip-Seq_NPCs_Mouse1.87404364
18ZNF274_21170338_ChIP-Seq_K562_Hela1.87079102
19CDX2_19796622_ChIP-Seq_MESCs_Mouse1.86989205
20SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.86210486
21NFE2_27457419_Chip-Seq_LIVER_Mouse1.85366930
22TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.82382808
23NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.81515787
24TAF15_26573619_Chip-Seq_HEK293_Human1.81058972
25NANOG_18555785_Chip-Seq_ESCs_Mouse1.80663798
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76403913
27EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.76199521
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.75737795
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75196540
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.74991842
31P300_19829295_ChIP-Seq_ESCs_Human1.74833185
32E2F1_18555785_Chip-Seq_ESCs_Mouse1.73845635
33PIAS1_25552417_ChIP-Seq_VCAP_Human1.71996336
34SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.71871723
35SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.70828040
36P53_22387025_ChIP-Seq_ESCs_Mouse1.70572213
37EZH2_27294783_Chip-Seq_NPCs_Mouse1.70479056
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.69856967
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.68941216
40SMAD4_21799915_ChIP-Seq_A2780_Human1.67667304
41SUZ12_18555785_Chip-Seq_ESCs_Mouse1.67209261
42VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.65648089
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.63063937
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.58646602
45TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58528712
46CMYC_18555785_Chip-Seq_ESCs_Mouse1.58337268
47BMI1_23680149_ChIP-Seq_NPCS_Mouse1.57158023
48STAT3_18555785_Chip-Seq_ESCs_Mouse1.54628788
49AHR_22903824_ChIP-Seq_MCF-7_Human1.52553151
50EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.52008961
51P300_18555785_Chip-Seq_ESCs_Mouse1.51583901
52EZH2_18974828_ChIP-Seq_MESCs_Mouse1.51154845
53RNF2_18974828_ChIP-Seq_MESCs_Mouse1.51154845
54NMYC_18555785_Chip-Seq_ESCs_Mouse1.46589397
55SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46582328
56ER_23166858_ChIP-Seq_MCF-7_Human1.46538054
57* STAT3_23295773_ChIP-Seq_U87_Human1.45628725
58RNF2_27304074_Chip-Seq_ESCs_Mouse1.44957910
59AR_21572438_ChIP-Seq_LNCaP_Human1.44892573
60JARID2_20075857_ChIP-Seq_MESCs_Mouse1.43791307
61NR3C1_21868756_ChIP-Seq_MCF10A_Human1.43368101
62DROSHA_22980978_ChIP-Seq_HELA_Human1.43210692
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.42382527
64OCT4_18555785_Chip-Seq_ESCs_Mouse1.42156315
65TCF4_18268006_ChIP-ChIP_LS174T_Human1.41593771
66FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.41502504
67RUNX1_27457419_Chip-Seq_LIVER_Mouse1.41383443
68SOX2_18555785_Chip-Seq_ESCs_Mouse1.40925418
69FUS_26573619_Chip-Seq_HEK293_Human1.40602848
70CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39741034
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39618023
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38514901
73TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38514901
74PU1_27457419_Chip-Seq_LIVER_Mouse1.38059647
75RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.37196923
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36541169
77* REST_21632747_ChIP-Seq_MESCs_Mouse1.36160392
78MTF2_20144788_ChIP-Seq_MESCs_Mouse1.35652422
79TCF4_23295773_ChIP-Seq_U87_Human1.33538005
80BCAT_22108803_ChIP-Seq_LS180_Human1.33272649
81TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.32146034
82SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.30878646
83BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.30611518
84EZH2_27294783_Chip-Seq_ESCs_Mouse1.30564942
85CBP_20019798_ChIP-Seq_JUKART_Human1.29217430
86IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29217430
87* SOX2_21211035_ChIP-Seq_LN229_Gbm1.29064622
88TP53_18474530_ChIP-ChIP_U2OS_Human1.28307463
89OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27476233
90KLF4_18555785_Chip-Seq_ESCs_Mouse1.26719112
91ZFX_18555785_Chip-Seq_ESCs_Mouse1.26364276
92CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25781602
93CTCF_18555785_Chip-Seq_ESCs_Mouse1.25773834
94ESRRB_18555785_Chip-Seq_ESCs_Mouse1.25566134
95AR_25329375_ChIP-Seq_VCAP_Human1.24961753
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24159520
97TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23774753
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23526280
99RNF2_27304074_Chip-Seq_NSC_Mouse1.22607413
100OCT4_21477851_ChIP-Seq_ESCs_Mouse1.22305622
101* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.22190645
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21585608
103NRF2_20460467_ChIP-Seq_MEFs_Mouse1.21435128
104NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.21435128
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21350683
106SMAD1_18555785_Chip-Seq_ESCs_Mouse1.21259472
107STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.20480189
108EP300_21415370_ChIP-Seq_HL-1_Mouse1.20237205
109SUZ12_27294783_Chip-Seq_ESCs_Mouse1.19820189
110SMAD3_21741376_ChIP-Seq_HESCs_Human1.19755245
111KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.19739933
112TAL1_26923725_Chip-Seq_HPCs_Mouse1.19335965
113CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19058251
114RUNX2_22187159_ChIP-Seq_PCA_Human1.19020562
115CRX_20693478_ChIP-Seq_RETINA_Mouse1.18926466
116EWS_26573619_Chip-Seq_HEK293_Human1.18440728
117TP53_16413492_ChIP-PET_HCT116_Human1.18180862
118* KDM2B_26808549_Chip-Seq_REH_Human1.16673884
119PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.15115471
120FOXM1_26456572_ChIP-Seq_MCF-7_Human1.14584329
121ARNT_22903824_ChIP-Seq_MCF-7_Human1.14429246
122CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14088248
123LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13838989
124VDR_22108803_ChIP-Seq_LS180_Human1.13429993
125LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11514653
126* FOXA2_19822575_ChIP-Seq_HepG2_Human1.08731771
127FLI1_21867929_ChIP-Seq_TH2_Mouse1.08246409
128NR3C1_23031785_ChIP-Seq_PC12_Mouse1.07474119
129SMAD4_21741376_ChIP-Seq_HESCs_Human1.05381374
130ESR1_20079471_ChIP-ChIP_T-47D_Human1.05211551
131TCF4_22108803_ChIP-Seq_LS180_Human1.04818057
132CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04379343
133MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04327860
134P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03712366
135KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02683133

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.75211139
2MP0003122_maternal_imprinting4.45950181
3MP0001188_hyperpigmentation3.90052927
4MP0005409_darkened_coat_color3.55204700
5MP0003136_yellow_coat_color3.25334890
6MP0003880_abnormal_central_pattern2.96425654
7MP0005171_absent_coat_pigmentation2.76505568
8MP0003195_calcinosis2.68814624
9MP0003121_genomic_imprinting2.66746611
10MP0000566_synostosis2.60036345
11MP0000015_abnormal_ear_pigmentation2.52474887
12MP0001486_abnormal_startle_reflex2.49587228
13MP0006292_abnormal_olfactory_placode2.40454585
14MP0004859_abnormal_synaptic_plasticity2.35760203
15MP0003787_abnormal_imprinting2.28175652
16MP0002102_abnormal_ear_morphology2.16365721
17MP0005645_abnormal_hypothalamus_physiol2.06164635
18MP0009046_muscle_twitch2.03349859
19MP0002735_abnormal_chemical_nociception2.03201397
20MP0002909_abnormal_adrenal_gland2.03047004
21MP0005174_abnormal_tail_pigmentation2.02400915
22MP0005646_abnormal_pituitary_gland1.90033757
23MP0009745_abnormal_behavioral_response1.89253367
24MP0005423_abnormal_somatic_nervous1.88600007
25MP0004742_abnormal_vestibular_system1.85683714
26MP0004381_abnormal_hair_follicle1.83245385
27MP0002876_abnormal_thyroid_physiology1.81865811
28MP0008260_abnormal_autophagy1.75593372
29MP0009780_abnormal_chondrocyte_physiolo1.70100258
30MP0002277_abnormal_respiratory_mucosa1.65320425
31MP0003635_abnormal_synaptic_transmissio1.64190033
32MP0001529_abnormal_vocalization1.63636629
33MP0003890_abnormal_embryonic-extraembry1.62048146
34MP0001968_abnormal_touch/_nociception1.61185694
35MP0000778_abnormal_nervous_system1.58714828
36MP0002572_abnormal_emotion/affect_behav1.51809342
37MP0002067_abnormal_sensory_capabilities1.48640202
38MP0001986_abnormal_taste_sensitivity1.48583981
39MP0002272_abnormal_nervous_system1.46514492
40MP0000920_abnormal_myelination1.45492251
41MP0001502_abnormal_circadian_rhythm1.44937495
42MP0002064_seizures1.41395381
43MP0002063_abnormal_learning/memory/cond1.38867093
44MP0003045_fibrosis1.37197904
45MP0004270_analgesia1.37159534
46MP0002233_abnormal_nose_morphology1.36043850
47MP0003950_abnormal_plasma_membrane1.35918645
48MP0001501_abnormal_sleep_pattern1.33947551
49MP0001346_abnormal_lacrimal_gland1.32507523
50MP0004885_abnormal_endolymph1.30293766
51MP0002736_abnormal_nociception_after1.30007816
52MP0003646_muscle_fatigue1.29566930
53MP0001440_abnormal_grooming_behavior1.28308696
54MP0002734_abnormal_mechanical_nocicepti1.26512376
55MP0005551_abnormal_eye_electrophysiolog1.26414763
56MP0000579_abnormal_nail_morphology1.26119816
57MP0004142_abnormal_muscle_tone1.25591438
58MP0009697_abnormal_copulation1.24320588
59MP0003011_delayed_dark_adaptation1.24084402
60MP0004484_altered_response_of1.22458520
61MP0000383_abnormal_hair_follicle1.20017024
62MP0001963_abnormal_hearing_physiology1.19879731
63MP0005187_abnormal_penis_morphology1.19549228
64MP0000631_abnormal_neuroendocrine_gland1.18710563
65MP0005451_abnormal_body_composition1.18474007
66MP0006276_abnormal_autonomic_nervous1.17241477
67MP0003123_paternal_imprinting1.13856638
68MP0004510_myositis1.13626245
69MP0002557_abnormal_social/conspecific_i1.13012296
70MP0004811_abnormal_neuron_physiology1.11862575
71MP0005394_taste/olfaction_phenotype1.10876944
72MP0005499_abnormal_olfactory_system1.10876944
73MP0000026_abnormal_inner_ear1.07589920
74MP0004133_heterotaxia1.06407233
75MP0004215_abnormal_myocardial_fiber1.04677106
76MP0005257_abnormal_intraocular_pressure1.04299599
77MP0003937_abnormal_limbs/digits/tail_de1.04220913
78MP0005410_abnormal_fertilization1.03067654
79MP0002095_abnormal_skin_pigmentation1.02188477
80MP0009764_decreased_sensitivity_to1.01907499
81MP0010329_abnormal_lipoprotein_level1.01165976
82MP0000749_muscle_degeneration1.00449213
83MP0002152_abnormal_brain_morphology0.99817512
84MP0001984_abnormal_olfaction0.98061360
85MP0008789_abnormal_olfactory_epithelium0.96791128
86MP0010678_abnormal_skin_adnexa0.95041335
87MP0002938_white_spotting0.95027510
88MP0005670_abnormal_white_adipose0.94702919
89MP0002148_abnormal_hypersensitivity_rea0.94645226
90MP0003868_abnormal_feces_composition0.91816581
91MP0001970_abnormal_pain_threshold0.91405384
92MP0002638_abnormal_pupillary_reflex0.91387701
93MP0004145_abnormal_muscle_electrophysio0.91015990
94MP0010386_abnormal_urinary_bladder0.90779369
95MP0001177_atelectasis0.90528348
96MP0002234_abnormal_pharynx_morphology0.90407360
97MP0001286_abnormal_eye_development0.88993183
98MP0002184_abnormal_innervation0.88508814
99MP0005167_abnormal_blood-brain_barrier0.88311428
100MP0000372_irregular_coat_pigmentation0.87860294
101MP0005195_abnormal_posterior_eye0.87767811
102MP0003942_abnormal_urinary_system0.86659284
103MP0003755_abnormal_palate_morphology0.86299447
104MP0002419_abnormal_innate_immunity0.86284025
105MP0009250_abnormal_appendicular_skeleto0.85846129
106MP0000427_abnormal_hair_cycle0.84096715
107MP0002177_abnormal_outer_ear0.83949596
108MP0003690_abnormal_glial_cell0.83204158
109MP0001324_abnormal_eye_pigmentation0.83200969
110MP0003861_abnormal_nervous_system0.83114349
111MP0002066_abnormal_motor_capabilities/c0.82919240
112MP0003632_abnormal_nervous_system0.81840401
113MP0003183_abnormal_peptide_metabolism0.79563125
114MP0003938_abnormal_ear_development0.79295322
115MP0000647_abnormal_sebaceous_gland0.79224165
116MP0001905_abnormal_dopamine_level0.78670183
117MP0005253_abnormal_eye_physiology0.78504259
118MP0004924_abnormal_behavior0.78464499
119MP0005386_behavior/neurological_phenoty0.78464499
120MP0002752_abnormal_somatic_nervous0.78278678
121MP0005379_endocrine/exocrine_gland_phen0.78090191
122MP0002127_abnormal_cardiovascular_syste0.77694585
123MP0001299_abnormal_eye_distance/0.76407969
124MP0002882_abnormal_neuron_morphology0.76148887
125MP0004134_abnormal_chest_morphology0.76045983
126MP0002229_neurodegeneration0.73824998
127MP0004043_abnormal_pH_regulation0.73672406
128MP0006072_abnormal_retinal_apoptosis0.73144393
129MP0005377_hearing/vestibular/ear_phenot0.71524179
130MP0003878_abnormal_ear_physiology0.71524179
131MP0001485_abnormal_pinna_reflex0.71224299
132MP0000955_abnormal_spinal_cord0.70863773
133MP0003935_abnormal_craniofacial_develop0.70634323
134MP0002009_preneoplasia0.69924585
135MP0001835_abnormal_antigen_presentation0.67754166
136MP0002163_abnormal_gland_morphology0.67643891
137MP0008569_lethality_at_weaning0.67548389
138MP0003724_increased_susceptibility_to0.67472924
139MP0002733_abnormal_thermal_nociception0.67142118
140MP0002998_abnormal_bone_remodeling0.65559173
141MP0008877_abnormal_DNA_methylation0.65274817
142MP0005248_abnormal_Harderian_gland0.64096432
143MP0000681_abnormal_thyroid_gland0.63999725
144MP0003631_nervous_system_phenotype0.63959872
145MP0003633_abnormal_nervous_system0.63922174
146MP0008995_early_reproductive_senescence0.62449272

Predicted human phenotypes

RankGene SetZ-score
1Febrile seizures (HP:0002373)4.66609267
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.47320404
3Focal motor seizures (HP:0011153)4.12272792
4Atonic seizures (HP:0010819)3.92453806
5Chromsome breakage (HP:0040012)3.90532178
6Prostate neoplasm (HP:0100787)3.61274964
7Papillary thyroid carcinoma (HP:0002895)3.41994762
8Hepatoblastoma (HP:0002884)3.24884822
9Absent/shortened dynein arms (HP:0200106)3.20834601
10Dynein arm defect of respiratory motile cilia (HP:0012255)3.20834601
11Abnormality of incisor morphology (HP:0011063)2.94879413
12Polyphagia (HP:0002591)2.72831613
13White forelock (HP:0002211)2.70902293
14Duplicated collecting system (HP:0000081)2.70629107
15Abnormality of the nasal septum (HP:0000419)2.68379055
16Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.66575583
17Deep venous thrombosis (HP:0002625)2.62600773
18Congenital sensorineural hearing impairment (HP:0008527)2.60895398
19Septo-optic dysplasia (HP:0100842)2.60143084
20Decreased central vision (HP:0007663)2.59315531
21Fair hair (HP:0002286)2.56929671
22Limb dystonia (HP:0002451)2.56810782
23Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.55939081
24Prolonged partial thromboplastin time (HP:0003645)2.54393246
25Abnormal ciliary motility (HP:0012262)2.53465381
26Patchy hypopigmentation of hair (HP:0011365)2.51665075
27Abnormality of the renal collecting system (HP:0004742)2.50710076
28Gait imbalance (HP:0002141)2.44814658
29Dyschromatopsia (HP:0007641)2.40321437
30Diastasis recti (HP:0001540)2.38702766
31True hermaphroditism (HP:0010459)2.37197405
32Dialeptic seizures (HP:0011146)2.36728503
33Aplasia cutis congenita (HP:0001057)2.35675144
34Broad-based gait (HP:0002136)2.35478350
35Gaze-evoked nystagmus (HP:0000640)2.34944905
36Absent speech (HP:0001344)2.29796303
37Medial flaring of the eyebrow (HP:0010747)2.26801312
38Eczematoid dermatitis (HP:0000976)2.26680808
39Intestinal atresia (HP:0011100)2.25212305
40Epileptic encephalopathy (HP:0200134)2.25152413
41Absence seizures (HP:0002121)2.24192784
42Abnormal hair whorl (HP:0010721)2.23722512
43Mesomelia (HP:0003027)2.20768131
44Generalized hypopigmentation of hair (HP:0011358)2.20018663
45Abnormal respiratory motile cilium physiology (HP:0012261)2.19998116
46Midline defect of the nose (HP:0004122)2.19199726
47Blue irides (HP:0000635)2.18911903
48Hyperventilation (HP:0002883)2.17259676
49Tubulointerstitial nephritis (HP:0001970)2.17084752
50Epidermoid cyst (HP:0200040)2.14831890
51Abnormality of the pubic bones (HP:0003172)2.13330294
52Genital tract atresia (HP:0001827)2.12628760
53Broad alveolar ridges (HP:0000187)2.12599175
54Recurrent abscess formation (HP:0002722)2.12319134
55Vaginal atresia (HP:0000148)2.10808298
56Protruding tongue (HP:0010808)2.06421174
57Sex reversal (HP:0012245)2.06215203
58Abnormal sex determination (HP:0012244)2.06215203
59Hip dysplasia (HP:0001385)2.06081900
60Abnormality of the labia minora (HP:0012880)2.05214974
61Submucous cleft hard palate (HP:0000176)2.04547688
62Lissencephaly (HP:0001339)2.04437413
63Progressive cerebellar ataxia (HP:0002073)2.04168324
64Recurrent gram-negative bacterial infections (HP:0005420)2.03576145
65Small epiphyses (HP:0010585)2.03147034
66Action tremor (HP:0002345)2.02858736
67Absent eyebrow (HP:0002223)2.01393668
68Chronic mucocutaneous candidiasis (HP:0002728)2.00044776
69Recurrent cutaneous fungal infections (HP:0011370)2.00044776
70Optic neuritis (HP:0100653)1.99812671
71Retrobulbar optic neuritis (HP:0100654)1.99812671
72Amyotrophic lateral sclerosis (HP:0007354)1.99640771
73Molar tooth sign on MRI (HP:0002419)1.99488113
74Abnormality of midbrain morphology (HP:0002418)1.99488113
75Ectopic kidney (HP:0000086)1.98642052
76Absent septum pellucidum (HP:0001331)1.95757616
77Labial hypoplasia (HP:0000066)1.95711574
78Obstructive lung disease (HP:0006536)1.95362284
79Chronic obstructive pulmonary disease (HP:0006510)1.95362284
80Chronic hepatic failure (HP:0100626)1.95202753
81Focal seizures (HP:0007359)1.94790312
82Parakeratosis (HP:0001036)1.94623960
83Arthropathy (HP:0003040)1.94394968
84Abnormal respiratory motile cilium morphology (HP:0005938)1.93786601
85Abnormal respiratory epithelium morphology (HP:0012253)1.93786601
86Congenital primary aphakia (HP:0007707)1.93433699
87Volvulus (HP:0002580)1.93316526
88Epileptiform EEG discharges (HP:0011182)1.93005288
89Thyroid carcinoma (HP:0002890)1.92819547
90Abnormality of the prostate (HP:0008775)1.91535568
91Optic nerve hypoplasia (HP:0000609)1.90722217
92EEG with generalized epileptiform discharges (HP:0011198)1.90653503
93Nephronophthisis (HP:0000090)1.89144017
94Conical tooth (HP:0000698)1.88871572
95Widely spaced teeth (HP:0000687)1.88510221
96Hypsarrhythmia (HP:0002521)1.88286342
97Abnormality of the corticospinal tract (HP:0002492)1.86965103
98Clubbing of toes (HP:0100760)1.86220933
99Abnormality of the renal medulla (HP:0100957)1.85603451
100Nephrogenic diabetes insipidus (HP:0009806)1.85204594
101Exotropia (HP:0000577)1.85039772
102Abnormality of the lower motor neuron (HP:0002366)1.84341502
103Osteomalacia (HP:0002749)1.84322282
104Upper limb muscle weakness (HP:0003484)1.83090244
105Decreased muscle mass (HP:0003199)1.82102515
106Recurrent bacterial skin infections (HP:0005406)1.81796548
107Abnormality of the wing of the ilium (HP:0011867)1.80559518
108Pulmonary artery stenosis (HP:0004415)1.79341391
109Exercise-induced muscle cramps (HP:0003710)1.78544999
110Fetal akinesia sequence (HP:0001989)1.78085714
111Congenital stationary night blindness (HP:0007642)1.77779190
112Hypoplastic iliac wings (HP:0002866)1.76842404
113Gingivitis (HP:0000230)1.75961763
114Distal lower limb amyotrophy (HP:0008944)1.75040840
115Absent frontal sinuses (HP:0002688)1.74280754
116Abnormality of the columella (HP:0009929)1.73897879
117Abnormal eating behavior (HP:0100738)1.73354568
118Abnormality of the septum pellucidum (HP:0007375)1.72685707
119Hemiparesis (HP:0001269)1.72501888
120Keratoconus (HP:0000563)1.72134735
121Increased corneal curvature (HP:0100692)1.72134735
122Congenital hepatic fibrosis (HP:0002612)1.72059792
123Calf muscle hypertrophy (HP:0008981)1.72030480
124Recurrent pneumonia (HP:0006532)1.70909104
125Abnormality of the parietal bone (HP:0002696)1.70482240
126Impaired vibration sensation in the lower limbs (HP:0002166)1.70404372
127Scrotal hypoplasia (HP:0000046)1.69842693
128Anomalous pulmonary venous return (HP:0010772)1.69548093
129Decreased lacrimation (HP:0000633)1.69231576
130Generalized tonic-clonic seizures (HP:0002069)1.69045240
131Excessive salivation (HP:0003781)1.68647370
132Drooling (HP:0002307)1.68647370
133Abnormality of the right ventricle (HP:0001707)1.68459669
134Aplasia/Hypoplasia of the sternum (HP:0006714)1.68118866
135Absent hand (HP:0004050)1.68084147
136Duplication of thumb phalanx (HP:0009942)1.67852866
137Hypoplastic nipples (HP:0002557)1.67624147
138Lower limb amyotrophy (HP:0007210)1.67607998
139Pancreatic cysts (HP:0001737)1.67059773
140Popliteal pterygium (HP:0009756)1.66799426
141Alacrima (HP:0000522)1.66791914
142Aplasia/Hypoplasia of the uvula (HP:0010293)1.66769819
143Median cleft lip (HP:0000161)1.66740332
144Pheochromocytoma (HP:0002666)1.66463924
145Urinary urgency (HP:0000012)1.66285738
146Specific learning disability (HP:0001328)1.65387388
147Nonprogressive disorder (HP:0003680)1.64663064
148Thyroid-stimulating hormone excess (HP:0002925)1.64115020
149Reduced antithrombin III activity (HP:0001976)1.63962743
150Hypomagnesemia (HP:0002917)1.63893955
151Inappropriate behavior (HP:0000719)1.63743159
152Muscle hypertrophy of the lower extremities (HP:0008968)1.63515001
153Degeneration of the lateral corticospinal tracts (HP:0002314)1.63417737
154Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.63417737
155Cupped ear (HP:0000378)1.63130401
156Hypothermia (HP:0002045)1.62821902
157Spastic tetraplegia (HP:0002510)1.62482458
158Abnormality of the frontal sinuses (HP:0002687)1.62445671
159Dyskinesia (HP:0100660)1.61921434
160Stomach cancer (HP:0012126)1.59941100
161Abnormality of the incisor (HP:0000676)1.59512129
162Bell-shaped thorax (HP:0001591)1.57452332
163Narrow forehead (HP:0000341)1.57244807
164Lip pit (HP:0100267)1.57235824
165Joint hemorrhage (HP:0005261)1.57043815
166Mediastinal lymphadenopathy (HP:0100721)1.56799416
167Attenuation of retinal blood vessels (HP:0007843)1.56142675
168Abnormality of salivation (HP:0100755)1.56140495
169Renal cortical cysts (HP:0000803)1.55815050
170Hypoplastic labia majora (HP:0000059)1.55812168
171Nasolacrimal duct obstruction (HP:0000579)1.55419812
172Hypoplastic female external genitalia (HP:0012815)1.55315465
173Recurrent fungal infections (HP:0002841)1.55140451
174Chronic diarrhea (HP:0002028)1.54780858
175Abnormality of the renal cortex (HP:0011035)1.54390136
176Poor coordination (HP:0002370)1.54341036
177Akinesia (HP:0002304)1.54265682

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.24154498
2TNIK4.03470471
3STK38L3.66106418
4INSRR2.43230369
5PRPF4B2.25835274
6IRAK42.11236882
7EIF2AK22.08029850
8MAP2K72.04689012
9NTRK32.01827206
10MAP3K141.80158404
11IRAK31.72144853
12EPHA41.71940953
13PAK31.70255557
14MKNK21.69207241
15GRK71.68463963
16TXK1.67364410
17PNCK1.59099582
18NUAK11.51478675
19MAPK131.51027553
20ZAK1.50357531
21SGK21.49996342
22PKN11.48779223
23CAMK1G1.47417838
24ADRBK21.45821998
25SIK31.44507526
26BMPR1B1.43166268
27MAP3K121.40327725
28YES11.40297325
29BRSK21.40241762
30RIPK41.39482901
31MAP3K21.34925142
32NLK1.33377835
33WNK41.29584280
34CAMK1D1.29290914
35CLK11.27886526
36MUSK1.26626746
37CDK31.25907890
38MAP2K41.22232349
39BMPR21.21544671
40CSNK1G21.19286712
41PHKG11.17518581
42PHKG21.17518581
43FGFR31.17423389
44SGK2231.12531531
45SGK4941.12531531
46DYRK21.12089437
47STK391.08728200
48KSR11.07790360
49NEK61.07040142
50TEC1.05285064
51IRAK11.03604044
52TRIM281.03568825
53BRD40.98395100
54EPHA30.97877118
55FGR0.96443366
56SIK20.96066249
57OXSR10.95930814
58OBSCN0.94473408
59MAP4K20.92445216
60SGK30.91953300
61GRK10.91770525
62AKT30.90610369
63MAP3K90.89477033
64WNK10.87712144
65IRAK20.86097974
66BCR0.85851323
67FES0.85687616
68CSNK1G10.85153026
69SGK10.84942706
70BLK0.84932105
71MINK10.84284931
72CAMK10.83646889
73PIK3CA0.82835051
74PRKCE0.80044277
75NTRK20.77280315
76MARK10.77178129
77MAP3K40.76417869
78PLK20.76233534
79DYRK1A0.76045875
80JAK10.74891393
81CAMK2A0.74758241
82FER0.73743054
83STK240.72064426
84DYRK1B0.70922726
85CAMK40.70915501
86MKNK10.67819491
87TGFBR20.67796162
88ROCK10.66007694
89PRKD20.64852304
90CSNK1G30.64339952
91PRKCZ0.63596917
92IKBKE0.62763263
93STK380.61351123
94PRKAA20.61327239
95TRPM70.60786485
96UHMK10.60367840
97MAP3K130.60266277
98PRKG10.59936788
99KSR20.59877327
100CAMK2B0.58781220
101STK110.58205774
102PRKCQ0.57383193
103IKBKB0.55509862
104FGFR20.55450991
105PRKAA10.55281415
106DAPK20.53841762
107PINK10.52735586
108TNK20.52451623
109FGFR10.52430421
110EPHB10.52394594
111ERBB30.51403892
112MAPK70.50331784
113MARK20.50314900
114RET0.49645260
115FGFR40.49118156
116CAMK2D0.47197554
117STK160.47100020
118CSNK1D0.47057168
119DMPK0.46287777
120CSNK1A1L0.46284045
121HCK0.46117003
122MAP3K60.45632052
123DYRK30.45423568
124LYN0.42893620
125RPS6KB10.42535153
126CDK50.41273693
127PIK3CG0.40643993
128WNK30.39100607
129PTK2B0.38879699
130RAF10.38404727
131LATS10.37784032
132MAP3K70.37579978
133ERBB20.36502168
134CSK0.35656144
135FRK0.35620702
136CDK90.35570712
137BRSK10.35126957
138CAMKK20.34889923
139PRKCG0.34824442
140PRKACB0.34514878
141TAOK10.34002502
142TAOK30.33769455

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.83978541
2Morphine addiction_Homo sapiens_hsa050322.06694020
3Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.94324999
4Glutamatergic synapse_Homo sapiens_hsa047241.86702936
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.74499061
6Complement and coagulation cascades_Homo sapiens_hsa046101.70379327
7Phototransduction_Homo sapiens_hsa047441.65256809
8Circadian entrainment_Homo sapiens_hsa047131.62722482
9Nitrogen metabolism_Homo sapiens_hsa009101.57378718
10Taste transduction_Homo sapiens_hsa047421.57285848
11Olfactory transduction_Homo sapiens_hsa047401.55493599
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.52486822
13Ether lipid metabolism_Homo sapiens_hsa005651.49379967
14Serotonergic synapse_Homo sapiens_hsa047261.42659939
15Autoimmune thyroid disease_Homo sapiens_hsa053201.38019251
16Axon guidance_Homo sapiens_hsa043601.37750283
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.37537579
18Calcium signaling pathway_Homo sapiens_hsa040201.37163181
19NF-kappa B signaling pathway_Homo sapiens_hsa040641.36458464
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.34837603
21Graft-versus-host disease_Homo sapiens_hsa053321.31430307
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.27377928
23Sphingolipid metabolism_Homo sapiens_hsa006001.27295938
24Salivary secretion_Homo sapiens_hsa049701.26496911
25GABAergic synapse_Homo sapiens_hsa047271.25528188
26Allograft rejection_Homo sapiens_hsa053301.21981355
27Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.21326362
28Vitamin digestion and absorption_Homo sapiens_hsa049771.19599728
29Hedgehog signaling pathway_Homo sapiens_hsa043401.15919168
30Cholinergic synapse_Homo sapiens_hsa047251.15576033
31cAMP signaling pathway_Homo sapiens_hsa040241.15399893
32Propanoate metabolism_Homo sapiens_hsa006401.13527451
33Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.12617049
34Renin secretion_Homo sapiens_hsa049241.12524030
35Rheumatoid arthritis_Homo sapiens_hsa053231.12456127
36Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.10282172
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09960343
38African trypanosomiasis_Homo sapiens_hsa051431.09915099
39Butanoate metabolism_Homo sapiens_hsa006501.09268875
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09258033
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.07501405
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.06577075
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.06542031
44Amphetamine addiction_Homo sapiens_hsa050311.06299397
45Regulation of autophagy_Homo sapiens_hsa041401.05649711
46Lysine degradation_Homo sapiens_hsa003101.05577985
47Fanconi anemia pathway_Homo sapiens_hsa034601.04599555
48Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.03769116
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02458089
50Histidine metabolism_Homo sapiens_hsa003401.02121895
51Steroid biosynthesis_Homo sapiens_hsa001001.01218531
52Staphylococcus aureus infection_Homo sapiens_hsa051501.00278913
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.99643636
54Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97356491
55Long-term potentiation_Homo sapiens_hsa047200.96681483
56Asthma_Homo sapiens_hsa053100.96553769
57Toll-like receptor signaling pathway_Homo sapiens_hsa046200.96442800
58Chemokine signaling pathway_Homo sapiens_hsa040620.96013123
59Insulin secretion_Homo sapiens_hsa049110.95990520
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95524408
61Aldosterone synthesis and secretion_Homo sapiens_hsa049250.95284793
62Adherens junction_Homo sapiens_hsa045200.94415248
63Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93910681
64Long-term depression_Homo sapiens_hsa047300.93745212
65Synaptic vesicle cycle_Homo sapiens_hsa047210.93476514
66Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.92180606
67Osteoclast differentiation_Homo sapiens_hsa043800.91722911
68Hippo signaling pathway_Homo sapiens_hsa043900.91185761
69Ovarian steroidogenesis_Homo sapiens_hsa049130.90810983
70Malaria_Homo sapiens_hsa051440.90514164
71ABC transporters_Homo sapiens_hsa020100.90417357
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89098533
73Starch and sucrose metabolism_Homo sapiens_hsa005000.88237641
74PPAR signaling pathway_Homo sapiens_hsa033200.88193046
75Hematopoietic cell lineage_Homo sapiens_hsa046400.87137702
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.85797525
77TNF signaling pathway_Homo sapiens_hsa046680.85309067
78Type II diabetes mellitus_Homo sapiens_hsa049300.83433989
79Fatty acid degradation_Homo sapiens_hsa000710.82920899
80Arachidonic acid metabolism_Homo sapiens_hsa005900.82288717
81Dorso-ventral axis formation_Homo sapiens_hsa043200.80879957
82beta-Alanine metabolism_Homo sapiens_hsa004100.79936186
83Inositol phosphate metabolism_Homo sapiens_hsa005620.79377792
84Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79131169
85Cocaine addiction_Homo sapiens_hsa050300.78910056
86Tight junction_Homo sapiens_hsa045300.78299392
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.78128342
88Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.78097725
89Ras signaling pathway_Homo sapiens_hsa040140.77902751
90Circadian rhythm_Homo sapiens_hsa047100.77557337
91Leishmaniasis_Homo sapiens_hsa051400.76775492
92Bile secretion_Homo sapiens_hsa049760.75179368
93Oxytocin signaling pathway_Homo sapiens_hsa049210.75027376
94Vascular smooth muscle contraction_Homo sapiens_hsa042700.73996994
95FoxO signaling pathway_Homo sapiens_hsa040680.73863836
96AMPK signaling pathway_Homo sapiens_hsa041520.73279104
97alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.73100631
98Dopaminergic synapse_Homo sapiens_hsa047280.72802360
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72737730
100Endometrial cancer_Homo sapiens_hsa052130.71758838
101Steroid hormone biosynthesis_Homo sapiens_hsa001400.71729064
102RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.71619268
103Linoleic acid metabolism_Homo sapiens_hsa005910.70904762
104Measles_Homo sapiens_hsa051620.70659912
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69923086
106Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.69862511
107Tuberculosis_Homo sapiens_hsa051520.69820759
108Protein export_Homo sapiens_hsa030600.69448763
109Glucagon signaling pathway_Homo sapiens_hsa049220.69240296
110ErbB signaling pathway_Homo sapiens_hsa040120.68814634
111Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68549668
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68227252
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.67929797
114cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67311919
115Fatty acid metabolism_Homo sapiens_hsa012120.67272875
116Choline metabolism in cancer_Homo sapiens_hsa052310.67232817
117MAPK signaling pathway_Homo sapiens_hsa040100.66641832
118Retinol metabolism_Homo sapiens_hsa008300.65418877
119Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64871041
120Fatty acid biosynthesis_Homo sapiens_hsa000610.64236373
121Phagosome_Homo sapiens_hsa041450.63988579
122Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.62754792
123Renal cell carcinoma_Homo sapiens_hsa052110.62097113
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61521448
125Gap junction_Homo sapiens_hsa045400.61447640
126Wnt signaling pathway_Homo sapiens_hsa043100.61400341
127Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60814304
128Tryptophan metabolism_Homo sapiens_hsa003800.60278898
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60218782
130Arginine biosynthesis_Homo sapiens_hsa002200.59345262
131Gastric acid secretion_Homo sapiens_hsa049710.59102533
132Insulin signaling pathway_Homo sapiens_hsa049100.58502497
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58087941
134Basal cell carcinoma_Homo sapiens_hsa052170.56791026
135Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56474135
136Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55752816
137Rap1 signaling pathway_Homo sapiens_hsa040150.55467879
138Jak-STAT signaling pathway_Homo sapiens_hsa046300.54311915
139Dilated cardiomyopathy_Homo sapiens_hsa054140.54137873
140Melanoma_Homo sapiens_hsa052180.53676642
141Estrogen signaling pathway_Homo sapiens_hsa049150.53246838
1422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.53225168
143Glycerolipid metabolism_Homo sapiens_hsa005610.52266728
144Sphingolipid signaling pathway_Homo sapiens_hsa040710.51934598
145Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51404765
146Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.50680409
147Pancreatic secretion_Homo sapiens_hsa049720.50585982
148Mineral absorption_Homo sapiens_hsa049780.49791301
149Fat digestion and absorption_Homo sapiens_hsa049750.49738261
150Collecting duct acid secretion_Homo sapiens_hsa049660.49351870
151Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49120407
152Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47262352

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