TMCO6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cellular response to interleukin-15 (GO:0071350)5.44328922
2ribosomal small subunit assembly (GO:0000028)5.12333816
3response to interleukin-15 (GO:0070672)5.03813659
4positive regulation of gamma-delta T cell activation (GO:0046645)4.77305809
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.54538529
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.46878214
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.46878214
8regulation of gamma-delta T cell differentiation (GO:0045586)4.32283740
9viral transcription (GO:0019083)4.20279753
10translational termination (GO:0006415)4.05294924
11DNA unwinding involved in DNA replication (GO:0006268)3.96035415
12antigen processing and presentation of endogenous antigen (GO:0019883)3.94490328
13regulation of gamma-delta T cell activation (GO:0046643)3.94149279
14tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.92943948
15RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.92943948
16antigen processing and presentation via MHC class Ib (GO:0002475)3.91674517
17translational elongation (GO:0006414)3.69709144
18DNA strand elongation involved in DNA replication (GO:0006271)3.65960640
19dendritic cell chemotaxis (GO:0002407)3.62750054
20DNA strand elongation (GO:0022616)3.55951347
21telomere maintenance via semi-conservative replication (GO:0032201)3.55288362
22negative regulation of erythrocyte differentiation (GO:0045647)3.53044667
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.48210382
24DNA deamination (GO:0045006)3.46897396
25nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.43120294
26positive regulation of B cell differentiation (GO:0045579)3.41937663
27mucosal-associated lymphoid tissue development (GO:0048537)3.41070960
28Peyers patch development (GO:0048541)3.41070960
29cotranslational protein targeting to membrane (GO:0006613)3.37010563
30protein targeting to ER (GO:0045047)3.35779710
31purine nucleotide salvage (GO:0032261)3.32092962
32DNA replication initiation (GO:0006270)3.29602441
33purine nucleobase biosynthetic process (GO:0009113)3.27855287
34viral mRNA export from host cell nucleus (GO:0046784)3.25029083
35mitochondrial RNA metabolic process (GO:0000959)3.24328729
36positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.21736577
37regulation of B cell differentiation (GO:0045577)3.20460925
38telomere maintenance via recombination (GO:0000722)3.19274980
39regulation of translational fidelity (GO:0006450)3.18124580
40folic acid-containing compound biosynthetic process (GO:0009396)3.17999274
41L-serine metabolic process (GO:0006563)3.17976843
42protein localization to endoplasmic reticulum (GO:0070972)3.17623125
43establishment of protein localization to endoplasmic reticulum (GO:0072599)3.16377042
44viral life cycle (GO:0019058)3.13193609
45GMP metabolic process (GO:0046037)3.09554204
46translational initiation (GO:0006413)3.08421277
47pentose-phosphate shunt (GO:0006098)3.02187616
48cellular protein complex disassembly (GO:0043624)3.01956531
49sulfur amino acid catabolic process (GO:0000098)3.00739641
50ribosomal small subunit biogenesis (GO:0042274)2.99547203
51mitotic chromosome condensation (GO:0007076)2.99011434
52rRNA modification (GO:0000154)2.98184849
53dendritic cell migration (GO:0036336)2.98117388
54tetrahydrofolate metabolic process (GO:0046653)2.97971841
55mitotic recombination (GO:0006312)2.97811337
56pseudouridine synthesis (GO:0001522)2.96347552
57regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.94986060
58folic acid metabolic process (GO:0046655)2.94463359
59folic acid-containing compound metabolic process (GO:0006760)2.90732220
60B cell receptor signaling pathway (GO:0050853)2.86546075
61telomere maintenance via telomere lengthening (GO:0010833)2.85436358
62regulation of B cell receptor signaling pathway (GO:0050855)2.84402144
63nuclear-transcribed mRNA catabolic process (GO:0000956)2.81867518
64maturation of SSU-rRNA (GO:0030490)2.81658150
65protein complex disassembly (GO:0043241)2.80369194
66homocysteine metabolic process (GO:0050667)2.79803752
67negative regulation of B cell apoptotic process (GO:0002903)2.78346164
68mitotic nuclear envelope disassembly (GO:0007077)2.75721375
69DNA ligation (GO:0006266)2.74045999
70NIK/NF-kappaB signaling (GO:0038061)2.73466505
71rRNA methylation (GO:0031167)2.73345607
72deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.71632394
73T cell homeostasis (GO:0043029)2.71553995
74negative regulation of histone methylation (GO:0031061)2.71345787
75serine family amino acid biosynthetic process (GO:0009070)2.71101308
76mRNA catabolic process (GO:0006402)2.70414271
77tRNA modification (GO:0006400)2.68833383
78telomere organization (GO:0032200)2.68033461
79RNA catabolic process (GO:0006401)2.67518891
80telomere maintenance (GO:0000723)2.66928606
81IMP biosynthetic process (GO:0006188)2.64976290
82response to interferon-beta (GO:0035456)2.64340472
83guanosine-containing compound biosynthetic process (GO:1901070)2.63241974
84immunoglobulin mediated immune response (GO:0016064)2.62499568
85CENP-A containing nucleosome assembly (GO:0034080)2.62374565
86negative regulation of RNA splicing (GO:0033119)2.60889786
87formation of translation preinitiation complex (GO:0001731)2.59768332
88peptidyl-lysine dimethylation (GO:0018027)2.59724880
89interferon-gamma production (GO:0032609)2.58901377
90regulation of erythrocyte differentiation (GO:0045646)2.57463801
91B cell mediated immunity (GO:0019724)2.56898675
92macromolecular complex disassembly (GO:0032984)2.56829169
93purine deoxyribonucleotide catabolic process (GO:0009155)2.55222928
94regulation of histone H3-K9 methylation (GO:0051570)2.55202955
95IMP metabolic process (GO:0046040)2.53809519
96nuclear pore organization (GO:0006999)2.51326028
97chromatin remodeling at centromere (GO:0031055)2.51158803
98nuclear envelope disassembly (GO:0051081)2.50838113
99membrane disassembly (GO:0030397)2.50838113
100poly(A)+ mRNA export from nucleus (GO:0016973)2.50293145
101Arp2/3 complex-mediated actin nucleation (GO:0034314)2.49306408
102NADPH regeneration (GO:0006740)2.48657136
103ribosome biogenesis (GO:0042254)2.48630368
104base-excision repair (GO:0006284)2.47824098
105regulation of histone H3-K27 methylation (GO:0061085)2.47798640
106T cell migration (GO:0072678)2.47632836
107neutrophil activation involved in immune response (GO:0002283)2.47191169
108ribosomal large subunit biogenesis (GO:0042273)2.47092381
109pteridine-containing compound biosynthetic process (GO:0042559)2.45086410
110negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.44634344
111regulation of regulatory T cell differentiation (GO:0045589)2.44345251
112positive regulation of granulocyte differentiation (GO:0030854)2.42594650
113translesion synthesis (GO:0019985)2.42145340
114nucleotide salvage (GO:0043173)2.39552045
115negative T cell selection (GO:0043383)2.39484008
116regulation of mitochondrial translation (GO:0070129)2.39338128
117kinetochore assembly (GO:0051382)2.38882067
118negative regulation of cell killing (GO:0031342)2.38801389
119negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.38801389
120snRNA processing (GO:0016180)2.36787405
121ribonucleoprotein complex biogenesis (GO:0022613)2.36650992
122nucleobase biosynthetic process (GO:0046112)2.36576058
123cysteine metabolic process (GO:0006534)2.36199040
124pteridine-containing compound metabolic process (GO:0042558)2.35374086
125DNA strand renaturation (GO:0000733)2.35260178
126defense response to protozoan (GO:0042832)2.34852913
127regulation of alpha-beta T cell proliferation (GO:0046640)2.34464215
128cellular response to interleukin-4 (GO:0071353)2.34024088
129response to peptidoglycan (GO:0032494)2.33692909
130negative thymic T cell selection (GO:0045060)2.33646257
1313-UTR-mediated mRNA stabilization (GO:0070935)2.33159673
132nucleotide-excision repair, DNA gap filling (GO:0006297)2.33002369
133negative regulation of phagocytosis (GO:0050765)2.32979887
134DNA duplex unwinding (GO:0032508)2.32189642
135snRNA metabolic process (GO:0016073)2.31558869
136peptidyl-histidine modification (GO:0018202)2.30634062
137purine-containing compound salvage (GO:0043101)2.30524463
138DNA replication-dependent nucleosome organization (GO:0034723)2.30320796
139DNA replication-dependent nucleosome assembly (GO:0006335)2.30320796
140macrophage differentiation (GO:0030225)2.29821465
141detection of bacterium (GO:0016045)2.29425378
142DNA replication-independent nucleosome organization (GO:0034724)2.29377598
143DNA replication-independent nucleosome assembly (GO:0006336)2.29377598
144intra-S DNA damage checkpoint (GO:0031573)2.29122343
145termination of RNA polymerase II transcription (GO:0006369)2.28804937
146deoxyribose phosphate catabolic process (GO:0046386)2.28706037
147megakaryocyte development (GO:0035855)2.28626656
148DNA geometric change (GO:0032392)2.28548591
149regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.28129267
150metallo-sulfur cluster assembly (GO:0031163)2.27829590
151iron-sulfur cluster assembly (GO:0016226)2.27829590
152positive regulation of megakaryocyte differentiation (GO:0045654)2.25583708
153positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.24538064
154transcription-coupled nucleotide-excision repair (GO:0006283)2.23358695
155pantothenate metabolic process (GO:0015939)2.23069563
156kinetochore organization (GO:0051383)2.22593159
157transcription from mitochondrial promoter (GO:0006390)2.22452121
158detection of other organism (GO:0098543)2.22137983
159regulation of B cell apoptotic process (GO:0002902)2.21758108
160deoxyribonucleotide catabolic process (GO:0009264)2.20718742
161regulation of helicase activity (GO:0051095)2.20559434
162tRNA processing (GO:0008033)2.20554618
163regulation of superoxide anion generation (GO:0032928)2.20139094
164nucleoside salvage (GO:0043174)2.19522197
165UTP biosynthetic process (GO:0006228)2.17506210
166adenosine metabolic process (GO:0046085)2.16089676
167glycine metabolic process (GO:0006544)2.15682832
168cytochrome complex assembly (GO:0017004)2.13822286
169positive regulation by symbiont of host defense response (GO:0052509)2.13778409
170modulation by symbiont of host defense response (GO:0052031)2.13778409
171modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.13778409
172modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.13778409
173positive regulation by organism of defense response of other organism involved in symbiotic interact2.13778409
174modulation by symbiont of host immune response (GO:0052553)2.13778409

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.81663369
2* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.40446350
3MYC_22102868_ChIP-Seq_BL_Human2.98797343
4ELF1_17652178_ChIP-ChIP_JURKAT_Human2.93760490
5MYC_18555785_ChIP-Seq_MESCs_Mouse2.86802843
6FOXM1_23109430_ChIP-Seq_U2OS_Human2.63222648
7IRF8_22096565_ChIP-ChIP_GC-B_Human2.43804166
8* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.40525310
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.36761380
10VDR_21846776_ChIP-Seq_THP-1_Human2.32373895
11* CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.27326919
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.25191966
13IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.20203671
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.18627153
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.13067974
16TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.12730496
17SCL_19346495_ChIP-Seq_HPC-7_Human2.09397122
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.08541786
19* CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.07900040
20MYC_18358816_ChIP-ChIP_MESCs_Mouse2.00293393
21* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.95615978
22EGR1_19374776_ChIP-ChIP_THP-1_Human1.95491546
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.93682982
24EST1_17652178_ChIP-ChIP_JURKAT_Human1.90296762
25MYC_19079543_ChIP-ChIP_MESCs_Mouse1.89449282
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82200585
27ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.80670663
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.79816323
29MYC_19030024_ChIP-ChIP_MESCs_Mouse1.79381155
30VDR_23849224_ChIP-Seq_CD4+_Human1.78959305
31* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.77340884
32CIITA_25753668_ChIP-Seq_RAJI_Human1.74934749
33* XRN2_22483619_ChIP-Seq_HELA_Human1.74369340
34SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.72558091
35MAF_26560356_Chip-Seq_TH1_Human1.71839829
36CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.71815871
37* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70742582
38SPI1_23547873_ChIP-Seq_NB4_Human1.68855870
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.66725435
40MYB_26560356_Chip-Seq_TH2_Human1.66681269
41NELFA_20434984_ChIP-Seq_ESCs_Mouse1.66278121
42UTX_26944678_Chip-Seq_JUKART_Human1.64316701
43ETS1_20019798_ChIP-Seq_JURKAT_Human1.60880470
44ERG_20887958_ChIP-Seq_HPC-7_Mouse1.59954735
45FOXP3_21729870_ChIP-Seq_TREG_Human1.57606074
46MYB_26560356_Chip-Seq_TH1_Human1.55569590
47HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.55400658
48STAT4_19710469_ChIP-ChIP_TH1__Mouse1.52403564
49NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.49334438
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.48775435
51RUNX1_22412390_ChIP-Seq_EML_Mouse1.48297640
52GATA1_22383799_ChIP-Seq_G1ME_Mouse1.47667372
53TCF7_22412390_ChIP-Seq_EML_Mouse1.45174283
54KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.44247748
55IRF8_21731497_ChIP-ChIP_J774_Mouse1.43240070
56PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.42092793
57GABP_19822575_ChIP-Seq_HepG2_Human1.41374294
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.40086435
59E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.39545521
60E2F1_18555785_ChIP-Seq_MESCs_Mouse1.39533537
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39352699
62DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.38189607
63* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.38018816
64NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.37460208
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.37397713
66CREB1_15753290_ChIP-ChIP_HEK293T_Human1.36849679
67TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36718490
68HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.33691258
69TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.33032388
70ZFX_18555785_ChIP-Seq_MESCs_Mouse1.31707442
71NOTCH1_21737748_ChIP-Seq_TLL_Human1.30174285
72MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.29140792
73BRD4_27068464_Chip-Seq_AML-cells_Mouse1.29044801
74VDR_24763502_ChIP-Seq_THP-1_Human1.28989569
75CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28465198
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.28439934
77GATA1_22025678_ChIP-Seq_K562_Human1.27064651
78FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.26164888
79MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.25638628
80MAF_26560356_Chip-Seq_TH2_Human1.25383233
81FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24708333
82NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.22897504
83E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.22799006
84RUNX_20019798_ChIP-Seq_JUKART_Human1.21422793
85YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20837697
86TFEB_21752829_ChIP-Seq_HELA_Human1.20786075
87TTF2_22483619_ChIP-Seq_HELA_Human1.19852442
88FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.18745670
89* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.18256806
90DCP1A_22483619_ChIP-Seq_HELA_Human1.17476182
91SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.17415937
92AR_21909140_ChIP-Seq_LNCAP_Human1.17189329
93* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.14388232
94LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.13761254
95NANOG_18555785_ChIP-Seq_MESCs_Mouse1.13673325
96BCL6_27268052_Chip-Seq_Bcells_Human1.13392764
97ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.12982519
98MYCN_18555785_ChIP-Seq_MESCs_Mouse1.12474141
99CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12358302
100THAP11_20581084_ChIP-Seq_MESCs_Mouse1.12266522
101KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12138017
102PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11673311
103P68_20966046_ChIP-Seq_HELA_Human1.11245880
104STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.09659369
105ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.08896334
106YY1_21170310_ChIP-Seq_MESCs_Mouse1.07596840
107POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07045279
108KDM5A_27292631_Chip-Seq_BREAST_Human1.06498874
109ELF1_20517297_ChIP-Seq_JURKAT_Human1.06366157
110* NCOR1_26117541_ChIP-Seq_K562_Human1.05810595
111MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04994641
112BCOR_27268052_Chip-Seq_Bcells_Human1.04692796
113IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.02607758
114PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01591337
115IRF8_27001747_Chip-Seq_BMDM_Mouse1.01330972
116ELK3_25401928_ChIP-Seq_HUVEC_Human1.01205790
117* SRF_21415370_ChIP-Seq_HL-1_Mouse1.00755544
118KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00586659
119* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.00480254
120STAT3_1855785_ChIP-Seq_MESCs_Mouse0.99920326
121KDM2B_26808549_Chip-Seq_DND41_Human0.99262324
122STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.98769373
123EGR1_23403033_ChIP-Seq_LIVER_Mouse0.98378319
124PPARA_22158963_ChIP-Seq_LIVER_Mouse0.96350424
125* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96217276
126SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.95637480
127CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.95224448
128EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.92282334

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system3.37488915
2MP0001835_abnormal_antigen_presentation3.24613842
3MP0000685_abnormal_immune_system3.09503476
4MP0005671_abnormal_response_to3.07006479
5MP0002132_abnormal_respiratory_system2.99336595
6MP0003763_abnormal_thymus_physiology2.72595067
7MP0003693_abnormal_embryo_hatching2.55632633
8MP0002398_abnormal_bone_marrow2.53810972
9MP0005360_urolithiasis2.50544714
10MP0006054_spinal_hemorrhage2.49306945
11MP0010094_abnormal_chromosome_stability2.47279647
12MP0001800_abnormal_humoral_immune2.47100640
13MP0009785_altered_susceptibility_to2.46504824
14MP0003077_abnormal_cell_cycle2.37490398
15MP0004957_abnormal_blastocyst_morpholog2.25320883
16MP0009333_abnormal_splenocyte_physiolog2.22318370
17MP0005397_hematopoietic_system_phenotyp2.20754786
18MP0001545_abnormal_hematopoietic_system2.20754786
19MP0003111_abnormal_nucleus_morphology2.19210382
20MP0000689_abnormal_spleen_morphology2.16326192
21MP0002420_abnormal_adaptive_immunity2.16236562
22MP0002723_abnormal_immune_serum2.16188605
23MP0003436_decreased_susceptibility_to2.13861402
24MP0005464_abnormal_platelet_physiology2.13703603
25MP0001819_abnormal_immune_cell2.12073569
26MP0002722_abnormal_immune_system2.11155106
27MP0002452_abnormal_antigen_presenting2.10987233
28MP0003786_premature_aging2.09601125
29MP0003656_abnormal_erythrocyte_physiolo2.09310092
30MP0004808_abnormal_hematopoietic_stem2.05244048
31MP0000716_abnormal_immune_system2.04090941
32MP0005000_abnormal_immune_tolerance2.02095321
33MP0005025_abnormal_response_to2.00852672
34MP0000490_abnormal_crypts_of1.96929696
35MP0000703_abnormal_thymus_morphology1.94801321
36MP0002429_abnormal_blood_cell1.90851319
37MP0008058_abnormal_DNA_repair1.89764861
38MP0008057_abnormal_DNA_replication1.80961218
39MP0006035_abnormal_mitochondrial_morpho1.79102424
40MP0008007_abnormal_cellular_replicative1.74780753
41MP0008875_abnormal_xenobiotic_pharmacok1.73404693
42MP0003866_abnormal_defecation1.70732825
43MP0010352_gastrointestinal_tract_polyps1.69816229
44MP0003806_abnormal_nucleotide_metabolis1.68415459
45MP0010155_abnormal_intestine_physiology1.66325914
46MP0002166_altered_tumor_susceptibility1.66211563
47MP0005387_immune_system_phenotype1.65026481
48MP0001790_abnormal_immune_system1.65026481
49MP0003172_abnormal_lysosome_physiology1.64034582
50MP0005083_abnormal_biliary_tract1.64016590
51MP0005075_abnormal_melanosome_morpholog1.63977727
52MP0002419_abnormal_innate_immunity1.61491234
53MP0002405_respiratory_system_inflammati1.61452756
54MP0002148_abnormal_hypersensitivity_rea1.60058892
55MP0002019_abnormal_tumor_incidence1.59763771
56MP0005174_abnormal_tail_pigmentation1.59494692
57MP0001853_heart_inflammation1.53034757
58MP0001661_extended_life_span1.51292672
59MP0008995_early_reproductive_senescence1.48707449
60MP0002006_tumorigenesis1.42757379
61MP0001845_abnormal_inflammatory_respons1.41861041
62MP0002254_reproductive_system_inflammat1.41395066
63MP0009278_abnormal_bone_marrow1.40477523
64MP0008260_abnormal_autophagy1.40180490
65MP0004147_increased_porphyrin_level1.35578765
66MP0006036_abnormal_mitochondrial_physio1.35348283
67MP0001873_stomach_inflammation1.32525543
68MP0000015_abnormal_ear_pigmentation1.31660042
69MP0001730_embryonic_growth_arrest1.28302369
70MP0003300_gastrointestinal_ulcer1.24630502
71MP0009697_abnormal_copulation1.23993708
72MP0005451_abnormal_body_composition1.22764782
73MP0000350_abnormal_cell_proliferation1.22140784
74MP0003878_abnormal_ear_physiology1.20107690
75MP0005377_hearing/vestibular/ear_phenot1.20107690
76MP0003191_abnormal_cellular_cholesterol1.19577068
77MP0000465_gastrointestinal_hemorrhage1.18778248
78MP0003252_abnormal_bile_duct1.18562064
79MP0010307_abnormal_tumor_latency1.18023649
80MP0000313_abnormal_cell_death1.16921118
81MP0003303_peritoneal_inflammation1.16210689
82MP0002277_abnormal_respiratory_mucosa1.15876573
83MP0004947_skin_inflammation1.15075207
84MP0008469_abnormal_protein_level1.14287830
85MP0005365_abnormal_bile_salt1.14013304
86MP0002095_abnormal_skin_pigmentation1.12281495
87MP0002928_abnormal_bile_duct1.06105814
88MP0008877_abnormal_DNA_methylation1.04034648
89MP0005332_abnormal_amino_acid1.02928790
90MP0000858_altered_metastatic_potential1.01764968
91MP0003195_calcinosis0.99668937
92MP0004185_abnormal_adipocyte_glucose0.98223258
93MP0002138_abnormal_hepatobiliary_system0.97213102
94MP0005085_abnormal_gallbladder_physiolo0.96406944
95MP0002653_abnormal_ependyma_morphology0.95767753
96MP0001986_abnormal_taste_sensitivity0.94827488
97MP0009764_decreased_sensitivity_to0.93495768
98MP0005084_abnormal_gallbladder_morpholo0.92808121
99MP0000358_abnormal_cell_content/0.90301439
100MP0004381_abnormal_hair_follicle0.88977550
101MP0002139_abnormal_hepatobiliary_system0.88791963
102MP0000371_diluted_coat_color0.88691118
103MP0000477_abnormal_intestine_morphology0.86607013
104MP0002933_joint_inflammation0.86013402
105MP0002080_prenatal_lethality0.85616987
106MP0005310_abnormal_salivary_gland0.85257703
107MP0003448_altered_tumor_morphology0.84307292
108MP0003724_increased_susceptibility_to0.83683072
109MP0003186_abnormal_redox_activity0.83022553
110MP0009763_increased_sensitivity_to0.81897986
111MP0002089_abnormal_postnatal_growth/wei0.80281964
112MP0003943_abnormal_hepatobiliary_system0.79450987
113MP0005670_abnormal_white_adipose0.79168481
114MP0000598_abnormal_liver_morphology0.76813734
115MP0003718_maternal_effect0.75844179
116MP0001697_abnormal_embryo_size0.75474787
117MP0000609_abnormal_liver_physiology0.75456114
118MP0000343_altered_response_to0.75084873
119MP0009840_abnormal_foam_cell0.75069516
120MP0005319_abnormal_enzyme/_coenzyme0.74787782
121MP0000678_abnormal_parathyroid_gland0.73803022
122MP0006082_CNS_inflammation0.73381663
123MP0009765_abnormal_xenobiotic_induced0.70799668
124MP0008873_increased_physiological_sensi0.68726694
125MP0005076_abnormal_cell_differentiation0.67751075
126MP0005023_abnormal_wound_healing0.65255405
127MP0001915_intracranial_hemorrhage0.64568428
128MP0001533_abnormal_skeleton_physiology0.63613555
129MP0002086_abnormal_extraembryonic_tissu0.62097803
130MP0001764_abnormal_homeostasis0.60513396
131MP0008932_abnormal_embryonic_tissue0.58970142
132MP0002136_abnormal_kidney_physiology0.58739638
133MP0004510_myositis0.53815533
134MP0001293_anophthalmia0.52862232
135MP0010329_abnormal_lipoprotein_level0.52405789
136MP0001663_abnormal_digestive_system0.52140885

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)4.09207535
2Thrombocytosis (HP:0001894)3.92775985
3Aplastic anemia (HP:0001915)3.90078230
4Recurrent viral infections (HP:0004429)3.79817221
5Abnormal number of erythroid precursors (HP:0012131)3.66294834
6Abnormality of cells of the erythroid lineage (HP:0012130)3.54825197
7Abnormal delayed hypersensitivity skin test (HP:0002963)3.53429816
8Abnormality of the heme biosynthetic pathway (HP:0010472)3.47251488
9Panhypogammaglobulinemia (HP:0003139)3.45975796
10Myositis (HP:0100614)3.45944756
11Abnormality of T cell physiology (HP:0011840)3.44963129
12Chronic otitis media (HP:0000389)3.39102434
13Abnormality of T cells (HP:0002843)3.28470900
14Recurrent bronchitis (HP:0002837)3.27295830
15Albinism (HP:0001022)3.21701334
16Chromosomal breakage induced by crosslinking agents (HP:0003221)3.19061655
17Recurrent abscess formation (HP:0002722)3.17251750
18Elevated erythrocyte sedimentation rate (HP:0003565)3.12660128
19Petechiae (HP:0000967)3.09859843
20Amaurosis fugax (HP:0100576)3.09767995
21Reticulocytopenia (HP:0001896)3.09586828
22Recurrent fungal infections (HP:0002841)3.03617804
23Abnormality of the nasal mucosa (HP:0000433)3.03462947
24Spontaneous hematomas (HP:0007420)3.01952972
25Constricted visual fields (HP:0001133)2.98026488
26T lymphocytopenia (HP:0005403)2.97913188
27Prolonged bleeding time (HP:0003010)2.95767241
28Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.90044850
29Abnormality of alanine metabolism (HP:0010916)2.90044850
30Hyperalaninemia (HP:0003348)2.90044850
31Epistaxis (HP:0000421)2.89906356
32Abnormality of pyrimidine metabolism (HP:0004353)2.89267334
33Chromsome breakage (HP:0040012)2.82736333
34Agammaglobulinemia (HP:0004432)2.82621128
35Anorexia (HP:0002039)2.82378272
36Recurrent bacterial skin infections (HP:0005406)2.78393489
37Gastrointestinal inflammation (HP:0004386)2.76612120
38Meningitis (HP:0001287)2.75310095
39Abnormality of T cell number (HP:0011839)2.74575352
40Abnormality of cells of the lymphoid lineage (HP:0012140)2.69255807
41Nasal polyposis (HP:0100582)2.67572410
42Inflammation of the large intestine (HP:0002037)2.67447064
43Abnormality of the fingertips (HP:0001211)2.67433274
44Lymphopenia (HP:0001888)2.66988257
45Poikiloderma (HP:0001029)2.63777110
46Recurrent gram-negative bacterial infections (HP:0005420)2.59089287
47Agnosia (HP:0010524)2.57244036
48Myelodysplasia (HP:0002863)2.57168064
49Abnormal platelet function (HP:0011869)2.55321184
50Impaired platelet aggregation (HP:0003540)2.55321184
51Lymphoma (HP:0002665)2.55184193
52Chronic mucocutaneous candidiasis (HP:0002728)2.53911866
53Recurrent cutaneous fungal infections (HP:0011370)2.53911866
54IgG deficiency (HP:0004315)2.52257084
55Colitis (HP:0002583)2.49231365
56Pustule (HP:0200039)2.48929053
57Hepatocellular necrosis (HP:0001404)2.48686532
58Hypoplasia of the thymus (HP:0000778)2.47661064
59Abnormal umbilical cord blood vessels (HP:0011403)2.46213716
60Single umbilical artery (HP:0001195)2.46213716
61Abnormality of the fetal cardiovascular system (HP:0010948)2.46213716
62Cellulitis (HP:0100658)2.45879935
63Mediastinal lymphadenopathy (HP:0100721)2.45403926
64Retrobulbar optic neuritis (HP:0100654)2.44498448
65Optic neuritis (HP:0100653)2.44498448
66Orchitis (HP:0100796)2.43325905
67Abnormality of DNA repair (HP:0003254)2.41229536
68Eczematoid dermatitis (HP:0000976)2.39253106
69Reduced antithrombin III activity (HP:0001976)2.37583945
70Encephalitis (HP:0002383)2.36980408
71Squamous cell carcinoma (HP:0002860)2.36453259
72Obstructive lung disease (HP:0006536)2.35674248
73Chronic obstructive pulmonary disease (HP:0006510)2.35674248
74Abnormality of B cell number (HP:0010975)2.35642623
75B lymphocytopenia (HP:0010976)2.35642623
76Abnormality of homocysteine metabolism (HP:0010919)2.34882568
77Homocystinuria (HP:0002156)2.34882568
78Abnormality of sulfur amino acid metabolism (HP:0004339)2.34816541
79Decreased electroretinogram (ERG) amplitude (HP:0000654)2.34443855
80Recurrent skin infections (HP:0001581)2.31913454
81Type I transferrin isoform profile (HP:0003642)2.31207627
82Abnormality of serum amino acid levels (HP:0003112)2.30353125
83Oral leukoplakia (HP:0002745)2.27650847
84Granulocytopenia (HP:0001913)2.27442784
85Gingival bleeding (HP:0000225)2.26733780
86Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.25822538
87Hematochezia (HP:0002573)2.25529270
88Microvesicular hepatic steatosis (HP:0001414)2.24888814
89Colon cancer (HP:0003003)2.24208785
90Hepatic necrosis (HP:0002605)2.24003578
91Gastrointestinal stroma tumor (HP:0100723)2.23234424
92Joint hemorrhage (HP:0005261)2.22097399
93Birth length less than 3rd percentile (HP:0003561)2.21976847
94Pallor (HP:0000980)2.20469870
95Recurrent sinusitis (HP:0011108)2.19780651
96Fatigue (HP:0012378)2.18825892
97Prolonged partial thromboplastin time (HP:0003645)2.18271258
98Vasculitis (HP:0002633)2.15145415
99Increased serum lactate (HP:0002151)2.11634981
100Chest pain (HP:0100749)2.09981310
101Hypochromic anemia (HP:0001931)2.07646627
102Ragged-red muscle fibers (HP:0003200)2.07397180
103Premature ovarian failure (HP:0008209)2.06258572
104Macrocytic anemia (HP:0001972)2.05998168
105Acute myeloid leukemia (HP:0004808)2.05792778
106Basal cell carcinoma (HP:0002671)2.05595349
107Acute hepatic failure (HP:0006554)2.05385669
108Abnormal biliary tract physiology (HP:0012439)2.03966309
109Bile duct proliferation (HP:0001408)2.03966309
110Cellular immunodeficiency (HP:0005374)2.03429938
111Pulmonary fibrosis (HP:0002206)2.02133263
112Increased serum ferritin (HP:0003281)2.01542329
113Abnormality of the preputium (HP:0100587)2.01368248
114Abnormality of reticulocytes (HP:0004312)1.99807319
115Hemoptysis (HP:0002105)1.99381972
116Abnormality of methionine metabolism (HP:0010901)1.98197991
117Polycythemia (HP:0001901)1.97088707
118Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.97019865
119Hyperglycinemia (HP:0002154)1.96974747
120Keratoconjunctivitis sicca (HP:0001097)1.96810864
121Attenuation of retinal blood vessels (HP:0007843)1.95461396
122Gastrointestinal infarctions (HP:0005244)1.94517284
123Arterial thrombosis (HP:0004420)1.94428197
124Pancytopenia (HP:0001876)1.93935164
125Abnormality of macrophages (HP:0004311)1.92941358
126Thrombophlebitis (HP:0004418)1.92775893
127Abnormality of iron homeostasis (HP:0011031)1.91718670
12811 pairs of ribs (HP:0000878)1.91696979
129Combined immunodeficiency (HP:0005387)1.90857392
130Interstitial pulmonary disease (HP:0006530)1.89972834
131Leukopenia (HP:0001882)1.89601916
132Hypochromic microcytic anemia (HP:0004840)1.88594791
133Bone marrow hypocellularity (HP:0005528)1.88227608
134Stomatitis (HP:0010280)1.87528233
135Hyperbilirubinemia (HP:0002904)1.87389123
136Bronchitis (HP:0012387)1.86754714
137Increased IgE level (HP:0003212)1.86668500
138Microcytic anemia (HP:0001935)1.86022236
139Hepatocellular carcinoma (HP:0001402)1.85895932
140Selective tooth agenesis (HP:0001592)1.85536648
141Increased density of long bones (HP:0006392)1.84713317
142Spastic diplegia (HP:0001264)1.84441882
143Abnormality of the ileum (HP:0001549)1.84269839
144Neutropenia (HP:0001875)1.83551090
145Abnormal protein glycosylation (HP:0012346)1.83387363
146Abnormal glycosylation (HP:0012345)1.83387363
147Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.83387363
148Abnormal protein N-linked glycosylation (HP:0012347)1.83387363
149Pulmonary embolism (HP:0002204)1.81412547
150Abnormality of monocarboxylic acid metabolism (HP:0010996)1.81126995
151Meckel diverticulum (HP:0002245)1.80129852
152Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.77873834
153Hypobetalipoproteinemia (HP:0003563)1.77118432
154Abnormality of chromosome stability (HP:0003220)1.74348040
155Urticaria (HP:0001025)1.72271787

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.82157382
2MAP4K13.69519943
3EEF2K3.06827374
4SMG12.75294259
5FLT32.59173605
6JAK32.56485665
7TGFBR22.24644359
8BTK2.23172839
9TYK22.18235658
10MAP3K102.10883270
11TGFBR12.09857701
12ZAP702.09503883
13BUB12.09075431
14NME22.01452213
15CDC71.99400620
16STK101.93491323
17SRPK11.89120649
18TAOK31.88294702
19KIT1.83156471
20ZAK1.82940270
21WEE11.75354984
22GRK61.75255787
23LRRK21.75209264
24MAP4K21.71400356
25NEK21.68176017
26MAPKAPK31.64568484
27IRAK41.64269135
28RIPK41.62587954
29BRSK21.59124003
30TAF11.58332468
31PKN21.58127253
32NME11.57874134
33MAP3K131.55534396
34CSF1R1.49505056
35RPS6KB21.49370924
36NEK11.47611531
37BLK1.44000736
38PASK1.43568901
39RPS6KA41.42649708
40MAP3K31.39374570
41CDK91.37696635
42SCYL21.36409715
43TEC1.36313129
44ERN11.34790379
45WNK41.25377935
46MAP3K81.24418479
47VRK11.22657698
48DYRK31.20157896
49NUAK11.19527295
50CDK121.19336950
51IKBKE1.19157679
52PIM11.18530748
53TBK11.18307358
54SYK1.15403143
55TXK1.14812396
56BRD41.14616755
57ACVR1B1.14613434
58ATR1.10173616
59HIPK21.05174347
60CLK11.04804080
61CDK41.03177948
62LCK1.01776660
63FGFR41.01571106
64MAP3K140.96921653
65TAOK10.92723449
66CDK70.92697806
67ITK0.91139048
68LYN0.86709327
69EIF2AK10.85971724
70MST40.85807138
71IKBKB0.84685248
72FGR0.83761785
73MAP2K30.83683504
74OXSR10.82455998
75TSSK60.80150246
76TESK20.80030057
77JAK20.79834614
78MAP3K70.76702326
79PBK0.76026703
80CCNB10.75364672
81HCK0.74642772
82BRSK10.73118893
83EPHB10.71185237
84CDK190.68661172
85MAP2K20.67341662
86TLK10.67253269
87MARK30.67166303
88PTK60.65929102
89STK40.65465833
90KDR0.64687867
91NLK0.64636449
92IRAK30.64304064
93AURKA0.63669559
94RAF10.61411030
95JAK10.60897267
96STK160.59692933
97FES0.58147079
98MATK0.57212162
99EIF2AK20.57098003
100PLK40.56645937
101MELK0.55948106
102BCKDK0.55041284
103AURKB0.54618963
104CHEK10.54608845
105CHUK0.53416160
106RPS6KA60.53392734
107CDK60.53244430
108KSR20.52709379
109STK390.52507561
110PIM20.50866463
111RPS6KC10.49828093
112RPS6KL10.49828093
113MAP3K110.48071395
114DYRK1B0.47308886
115CSK0.45586511
116ICK0.45205742
117TTK0.45124162
118PAK40.45020970
119MAP3K60.44286178
120PLK30.44016942
121PLK10.41233599
122DAPK10.40751903
123YES10.40333087
124TNK20.39571316
125SIK10.37820945
126MAPK110.37774060
127TRPM70.36925733
128MAP2K60.36356305
129CHEK20.36307241
130STK240.36119781
131ATM0.34963662
132MAP3K50.33912799

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.38907236
2Mismatch repair_Homo sapiens_hsa034303.40707545
3Ribosome_Homo sapiens_hsa030103.26735457
4Primary immunodeficiency_Homo sapiens_hsa053402.89784966
5Base excision repair_Homo sapiens_hsa034102.77173598
6Spliceosome_Homo sapiens_hsa030402.58405918
7Homologous recombination_Homo sapiens_hsa034402.28933137
8Antigen processing and presentation_Homo sapiens_hsa046122.17084872
9Nucleotide excision repair_Homo sapiens_hsa034202.11390951
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.96532181
11One carbon pool by folate_Homo sapiens_hsa006701.95358024
12RNA polymerase_Homo sapiens_hsa030201.90349312
13Sulfur relay system_Homo sapiens_hsa041221.88914293
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.77285864
15Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.74696656
162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.74397240
17Non-homologous end-joining_Homo sapiens_hsa034501.72239705
18Cell cycle_Homo sapiens_hsa041101.69511041
19Pyrimidine metabolism_Homo sapiens_hsa002401.69224001
20RNA transport_Homo sapiens_hsa030131.68119816
21Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.64613635
22B cell receptor signaling pathway_Homo sapiens_hsa046621.63854944
23RNA degradation_Homo sapiens_hsa030181.63669185
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.59506700
25Herpes simplex infection_Homo sapiens_hsa051681.59287161
26Pentose phosphate pathway_Homo sapiens_hsa000301.53480408
27Leishmaniasis_Homo sapiens_hsa051401.48554227
28Measles_Homo sapiens_hsa051621.47056078
29NF-kappa B signaling pathway_Homo sapiens_hsa040641.38887232
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.37018821
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.30635139
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26242456
33Hematopoietic cell lineage_Homo sapiens_hsa046401.23735058
34RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.22734358
35Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.21887572
36Systemic lupus erythematosus_Homo sapiens_hsa053221.18788693
37Proteasome_Homo sapiens_hsa030501.16645325
38Legionellosis_Homo sapiens_hsa051341.15222543
39Fanconi anemia pathway_Homo sapiens_hsa034601.15114930
40Arginine biosynthesis_Homo sapiens_hsa002201.14086911
41p53 signaling pathway_Homo sapiens_hsa041151.14028672
42Viral carcinogenesis_Homo sapiens_hsa052031.13688107
43Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.13544451
44Acute myeloid leukemia_Homo sapiens_hsa052211.07464949
45Cyanoamino acid metabolism_Homo sapiens_hsa004601.06525226
46Transcriptional misregulation in cancer_Homo sapiens_hsa052021.04777159
47Selenocompound metabolism_Homo sapiens_hsa004501.01923186
48Intestinal immune network for IgA production_Homo sapiens_hsa046721.01453186
49Epstein-Barr virus infection_Homo sapiens_hsa051690.98773200
50Peroxisome_Homo sapiens_hsa041460.96071106
51Retinol metabolism_Homo sapiens_hsa008300.94449414
52Osteoclast differentiation_Homo sapiens_hsa043800.92675308
53mRNA surveillance pathway_Homo sapiens_hsa030150.92114484
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91559403
55T cell receptor signaling pathway_Homo sapiens_hsa046600.90718565
56HTLV-I infection_Homo sapiens_hsa051660.90449839
57Influenza A_Homo sapiens_hsa051640.89397579
58Basal transcription factors_Homo sapiens_hsa030220.89264876
59Apoptosis_Homo sapiens_hsa042100.87555850
60Jak-STAT signaling pathway_Homo sapiens_hsa046300.87312560
61Shigellosis_Homo sapiens_hsa051310.87273883
62Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.86587722
63Notch signaling pathway_Homo sapiens_hsa043300.83808580
64Hepatitis B_Homo sapiens_hsa051610.82582162
65Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.82365115
66NOD-like receptor signaling pathway_Homo sapiens_hsa046210.80856333
67Fructose and mannose metabolism_Homo sapiens_hsa000510.80828656
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.80711653
69Chronic myeloid leukemia_Homo sapiens_hsa052200.79031196
70Pancreatic cancer_Homo sapiens_hsa052120.77654146
71Biosynthesis of amino acids_Homo sapiens_hsa012300.74619822
72Other glycan degradation_Homo sapiens_hsa005110.74587722
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74331167
74Glycosaminoglycan degradation_Homo sapiens_hsa005310.74029604
75Autoimmune thyroid disease_Homo sapiens_hsa053200.73806560
76Purine metabolism_Homo sapiens_hsa002300.73681468
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.73167702
78Phenylalanine metabolism_Homo sapiens_hsa003600.73018221
79Complement and coagulation cascades_Homo sapiens_hsa046100.72489958
80Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.69363579
81N-Glycan biosynthesis_Homo sapiens_hsa005100.68714120
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.67855846
83Chemokine signaling pathway_Homo sapiens_hsa040620.67571123
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.66901269
85Folate biosynthesis_Homo sapiens_hsa007900.66335474
86Graft-versus-host disease_Homo sapiens_hsa053320.65270140
87Staphylococcus aureus infection_Homo sapiens_hsa051500.64367925
88Chemical carcinogenesis_Homo sapiens_hsa052040.63985213
89Pertussis_Homo sapiens_hsa051330.63875923
90Toll-like receptor signaling pathway_Homo sapiens_hsa046200.63607967
91Caffeine metabolism_Homo sapiens_hsa002320.62909599
92Glutathione metabolism_Homo sapiens_hsa004800.62161407
93Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61946906
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.61785971
95Metabolic pathways_Homo sapiens_hsa011000.61552869
96Platelet activation_Homo sapiens_hsa046110.61400329
97Drug metabolism - other enzymes_Homo sapiens_hsa009830.61369285
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.60224926
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.58448192
100Regulation of autophagy_Homo sapiens_hsa041400.58376916
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58360613
102Toxoplasmosis_Homo sapiens_hsa051450.57793965
103Butanoate metabolism_Homo sapiens_hsa006500.57649460
104Tyrosine metabolism_Homo sapiens_hsa003500.57156558
105Arachidonic acid metabolism_Homo sapiens_hsa005900.56738943
106Colorectal cancer_Homo sapiens_hsa052100.56454225
107Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55197835
108ABC transporters_Homo sapiens_hsa020100.55186417
109Fatty acid degradation_Homo sapiens_hsa000710.55133151
110Thyroid cancer_Homo sapiens_hsa052160.52859623
111Viral myocarditis_Homo sapiens_hsa054160.49912365
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48892943
113Pyruvate metabolism_Homo sapiens_hsa006200.48679810
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.46351160
115Leukocyte transendothelial migration_Homo sapiens_hsa046700.44518846
116Galactose metabolism_Homo sapiens_hsa000520.44491381
117Propanoate metabolism_Homo sapiens_hsa006400.44216907
118Tuberculosis_Homo sapiens_hsa051520.43714936
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43092667
120Lysine degradation_Homo sapiens_hsa003100.42861446
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.42160709
122Carbon metabolism_Homo sapiens_hsa012000.42076869
123Protein export_Homo sapiens_hsa030600.39627658
124Type I diabetes mellitus_Homo sapiens_hsa049400.38797479
125Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.38700691
126Non-small cell lung cancer_Homo sapiens_hsa052230.38692134
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.37276137
128Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35307936
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33958297
130Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33007887
131Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.29505017
132Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29288863
133Allograft rejection_Homo sapiens_hsa053300.28852339
134Alcoholism_Homo sapiens_hsa050340.28568353
135Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.28116892

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