TMED7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.13900932
2L-phenylalanine catabolic process (GO:0006559)4.13900932
3hemidesmosome assembly (GO:0031581)4.06016919
4protein retention in ER lumen (GO:0006621)4.04574739
5COPI coating of Golgi vesicle (GO:0048205)3.85007268
6Golgi transport vesicle coating (GO:0048200)3.85007268
7L-phenylalanine metabolic process (GO:0006558)3.70077421
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.70077421
9skin morphogenesis (GO:0043589)3.64658936
10alpha-linolenic acid metabolic process (GO:0036109)3.50704403
11desmosome organization (GO:0002934)3.44527417
12protein hydroxylation (GO:0018126)3.27757863
13protein carboxylation (GO:0018214)3.26286029
14peptidyl-glutamic acid carboxylation (GO:0017187)3.26286029
15regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.25142033
16protein localization to endosome (GO:0036010)3.16715072
17peptidyl-proline hydroxylation (GO:0019511)3.13704460
18aromatic amino acid family catabolic process (GO:0009074)3.10240085
19cysteine metabolic process (GO:0006534)3.09387137
20iron ion import (GO:0097286)3.09353713
21regulation of transforming growth factor beta1 production (GO:0032908)3.08579784
22regulation of transforming growth factor beta2 production (GO:0032909)3.03715804
23collagen fibril organization (GO:0030199)3.02226937
24sulfur amino acid catabolic process (GO:0000098)3.02214911
25UDP-N-acetylglucosamine metabolic process (GO:0006047)3.02142911
26myelin maintenance (GO:0043217)2.95636093
27retina vasculature morphogenesis in camera-type eye (GO:0061299)2.90611186
28paraxial mesoderm development (GO:0048339)2.89549608
29regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.88495043
30homocysteine metabolic process (GO:0050667)2.87553207
31bile acid biosynthetic process (GO:0006699)2.86618790
32sequestering of extracellular ligand from receptor (GO:0035581)2.86172492
33negative regulation of fibrinolysis (GO:0051918)2.79915239
34drug transmembrane transport (GO:0006855)2.79704075
35wound healing, spreading of epidermal cells (GO:0035313)2.79698292
36chondrocyte proliferation (GO:0035988)2.79204255
37endodermal cell differentiation (GO:0035987)2.79143073
38plasma lipoprotein particle clearance (GO:0034381)2.79007334
39long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.77403221
40membrane budding (GO:0006900)2.76653483
41complement activation, alternative pathway (GO:0006957)2.75885595
42cell adhesion mediated by integrin (GO:0033627)2.75873806
43glyoxylate metabolic process (GO:0046487)2.75212718
44nuclear pore complex assembly (GO:0051292)2.74016732
45COPII vesicle coating (GO:0048208)2.73669262
46response to lipoprotein particle (GO:0055094)2.72965359
47triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.71903219
48bundle of His cell to Purkinje myocyte communication (GO:0086069)2.71228317
49negative regulation of anoikis (GO:2000811)2.71068505
50negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.70702048
51nucleotide-sugar biosynthetic process (GO:0009226)2.70408944
52mesodermal cell differentiation (GO:0048333)2.70261516
534-hydroxyproline metabolic process (GO:0019471)2.69024556
54fatty-acyl-CoA biosynthetic process (GO:0046949)2.66735128
55bile acid metabolic process (GO:0008206)2.66240162
56negative regulation of protein activation cascade (GO:2000258)2.64684380
57intestinal cholesterol absorption (GO:0030299)2.64225340
58cellular zinc ion homeostasis (GO:0006882)2.64143047
59regulation of fibrinolysis (GO:0051917)2.62975086
60low-density lipoprotein particle clearance (GO:0034383)2.61761249
61fatty acid elongation (GO:0030497)2.61341412
62reverse cholesterol transport (GO:0043691)2.60943249
63membrane protein ectodomain proteolysis (GO:0006509)2.60692559
64negative regulation of complement activation (GO:0045916)2.60374120
65protein N-linked glycosylation via asparagine (GO:0018279)2.58866891
66regulation of plasminogen activation (GO:0010755)2.58657366
67regulation of protein activation cascade (GO:2000257)2.58416998
68negative regulation of protein localization to plasma membrane (GO:1903077)2.57619929
69peptidyl-asparagine modification (GO:0018196)2.56311711
70negative regulation of chondrocyte differentiation (GO:0032331)2.56307752
71cellular modified amino acid catabolic process (GO:0042219)2.55539795
72apoptotic cell clearance (GO:0043277)2.55269528
73cell-substrate junction assembly (GO:0007044)2.53738047
74substrate-dependent cell migration (GO:0006929)2.53534248
75regulation of cholesterol homeostasis (GO:2000188)2.53503634
76regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.53438800
77cholesterol efflux (GO:0033344)2.53196766
78high-density lipoprotein particle remodeling (GO:0034375)2.52214552
79regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.52005732
80positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.51964729
81very long-chain fatty acid metabolic process (GO:0000038)2.50684408
82ER to Golgi vesicle-mediated transport (GO:0006888)2.50571371
83urea metabolic process (GO:0019627)2.49494527
84urea cycle (GO:0000050)2.49494527
85regulation of transforming growth factor beta production (GO:0071634)2.49304456
86maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.49078558
87protein N-linked glycosylation (GO:0006487)2.47558553
88tyrosine metabolic process (GO:0006570)2.46845769
89regulation of complement activation (GO:0030449)2.45120583
90chondrocyte development (GO:0002063)2.44657492
91endoplasmic reticulum unfolded protein response (GO:0030968)2.44208263
92positive regulation of nuclease activity (GO:0032075)2.44055945
93hippo signaling (GO:0035329)2.43712271
94short-chain fatty acid metabolic process (GO:0046459)2.42716217
95central nervous system myelination (GO:0022010)2.42614261
96axon ensheathment in central nervous system (GO:0032291)2.42614261
97glutamate metabolic process (GO:0006536)2.42239197
98ER-nucleus signaling pathway (GO:0006984)2.41845730
99growth hormone receptor signaling pathway (GO:0060396)2.41714932
100positive regulation of glycolytic process (GO:0045821)2.41670793
101asymmetric protein localization (GO:0008105)2.40645985
102protein localization to cell surface (GO:0034394)2.40594691
103negative regulation of neurotransmitter secretion (GO:0046929)2.40373824
104Golgi organization (GO:0007030)2.39784380
105regulation of lipoprotein metabolic process (GO:0050746)2.39416499
106regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.38819288
107response to methylmercury (GO:0051597)2.38545051
108fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.37994762
109intestinal absorption (GO:0050892)2.37967053
110retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.37782494
111gap junction assembly (GO:0016264)2.37770767
112activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.37080827
113sequestering of metal ion (GO:0051238)2.37004344
114cellular ketone body metabolic process (GO:0046950)2.36851743
115nuclear pore organization (GO:0006999)2.36774127
116fibrinolysis (GO:0042730)2.35423713
117very-low-density lipoprotein particle assembly (GO:0034379)2.35406717
118macroautophagy (GO:0016236)2.34699630
119lipoprotein metabolic process (GO:0042157)2.34450302
120endoplasmic reticulum organization (GO:0007029)2.34263362
121cellular response to unfolded protein (GO:0034620)2.34030785
122regulation of extracellular matrix disassembly (GO:0010715)2.33165316
123epithelial cell-cell adhesion (GO:0090136)2.31404353
124positive regulation of osteoblast proliferation (GO:0033690)2.31391901
125positive regulation of glycoprotein metabolic process (GO:1903020)2.31140689
126vesicle coating (GO:0006901)2.31108156
127cellular response to vitamin D (GO:0071305)2.31028117
128negative regulation of fatty acid transport (GO:2000192)2.30793790
129phospholipid homeostasis (GO:0055091)2.30237123
130protein-lipid complex assembly (GO:0065005)2.30035867
131smooth muscle tissue development (GO:0048745)2.29315001
132cellular copper ion homeostasis (GO:0006878)2.28681057
133regulation of membrane protein ectodomain proteolysis (GO:0051043)2.28565002
134triglyceride homeostasis (GO:0070328)2.28287530
135acylglycerol homeostasis (GO:0055090)2.28287530
136ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.28215778
137endocrine pancreas development (GO:0031018)2.27609148
138ER overload response (GO:0006983)2.26118794
139zinc ion transmembrane transport (GO:0071577)2.25951791
140acyl-CoA biosynthetic process (GO:0071616)2.25505305
141thioester biosynthetic process (GO:0035384)2.25505305
142cell migration involved in sprouting angiogenesis (GO:0002042)2.25337747
143fatty-acyl-CoA metabolic process (GO:0035337)2.25168193
144adhesion of symbiont to host cell (GO:0044650)2.25081233
145virion attachment to host cell (GO:0019062)2.25081233
146lysine metabolic process (GO:0006553)2.24967727
147lysine catabolic process (GO:0006554)2.24967727
148midgut development (GO:0007494)2.24760547
149protein-lipid complex remodeling (GO:0034368)2.23757319
150macromolecular complex remodeling (GO:0034367)2.23757319
151plasma lipoprotein particle remodeling (GO:0034369)2.23757319
152mesenchymal-epithelial cell signaling (GO:0060638)2.23704797
153kynurenine metabolic process (GO:0070189)2.23585430
154bile acid and bile salt transport (GO:0015721)2.23144779
155G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.22941491
156long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.22817847
157cholesterol transport (GO:0030301)2.22811823
158sterol transport (GO:0015918)2.22811823
159positive regulation of fatty acid beta-oxidation (GO:0032000)2.22123944
160regulation of cholesterol biosynthetic process (GO:0045540)2.22108491
161cytoskeletal anchoring at plasma membrane (GO:0007016)2.21837495
162cellular response to vitamin (GO:0071295)2.21728444
163sterol homeostasis (GO:0055092)2.21551239
164localization within membrane (GO:0051668)2.21143603
165epoxygenase P450 pathway (GO:0019373)2.21035562
166dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.20999577
167zinc ion transport (GO:0006829)2.20363816
168lipid translocation (GO:0034204)2.20319664
169phospholipid translocation (GO:0045332)2.20319664
170embryonic process involved in female pregnancy (GO:0060136)2.19714554
171nitrogen cycle metabolic process (GO:0071941)2.19567117
172tryptophan metabolic process (GO:0006568)2.19253067
173keratan sulfate catabolic process (GO:0042340)2.19088745
174substrate adhesion-dependent cell spreading (GO:0034446)2.19054619
175regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.18956424
176morphogenesis of an epithelial sheet (GO:0002011)2.17703284
177hypotonic response (GO:0006971)2.17272315

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.30883860
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.26438349
3RXR_22158963_ChIP-Seq_LIVER_Mouse3.23883543
4LXR_22158963_ChIP-Seq_LIVER_Mouse3.10734523
5TRIM28_21343339_ChIP-Seq_HEK293_Human2.90239184
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.88290725
7PPARA_22158963_ChIP-Seq_LIVER_Mouse2.71021502
8AR_21909140_ChIP-Seq_LNCAP_Human2.62926440
9PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.47606077
10CLOCK_20551151_ChIP-Seq_293T_Human2.15279935
11BRD4_25478319_ChIP-Seq_HGPS_Human2.12560463
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.10160500
13CDX2_19796622_ChIP-Seq_MESCs_Mouse2.03209413
14GATA1_22025678_ChIP-Seq_K562_Human2.01768124
15TP63_17297297_ChIP-ChIP_HaCaT_Human2.00846965
16NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.97896651
17HIF1A_21447827_ChIP-Seq_MCF-7_Human1.95264458
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.87716815
19ZNF217_24962896_ChIP-Seq_MCF-7_Human1.84913319
20NRF2_20460467_ChIP-Seq_MEFs_Mouse1.84545629
21NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.84545629
22ZNF263_19887448_ChIP-Seq_K562_Human1.78119780
23FOXO3_23340844_ChIP-Seq_DLD1_Human1.77790810
24FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.76286592
25SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.73196099
26SALL1_21062744_ChIP-ChIP_HESCs_Human1.72519900
27RBPJ_22232070_ChIP-Seq_NCS_Mouse1.69307604
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.68672003
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.67410342
30SOX2_27498859_Chip-Seq_STOMACH_Mouse1.66783938
31FOXA2_19822575_ChIP-Seq_HepG2_Human1.59764243
32NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.59660957
33KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.59232329
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.58869475
35BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.55537873
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.54880570
37Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.53693547
38PIAS1_25552417_ChIP-Seq_VCAP_Human1.48587755
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.48377313
40SOX2_20726797_ChIP-Seq_SW620_Human1.43805685
41EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.42788537
42AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.41895583
43AR_21572438_ChIP-Seq_LNCaP_Human1.41763937
44SALL4_18804426_ChIP-ChIP_XEN_Mouse1.39542361
45TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.38134159
46SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35201747
47RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.34695848
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34083221
49PPAR_26484153_Chip-Seq_NCI-H1993_Human1.34056001
50ESR2_21235772_ChIP-Seq_MCF-7_Human1.33633735
51FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.31508443
52TP53_16413492_ChIP-PET_HCT116_Human1.30848429
53SOX17_20123909_ChIP-Seq_XEN_Mouse1.30563433
54SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.29109870
55OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27170452
56KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.26970402
57CJUN_26792858_Chip-Seq_BT549_Human1.26818910
58CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.22636001
59SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.22067181
60EP300_21415370_ChIP-Seq_HL-1_Mouse1.21174004
61VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.19363448
62TCF4_18268006_ChIP-ChIP_LS174T_Human1.18217744
63TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17886030
64TP53_18474530_ChIP-ChIP_U2OS_Human1.17817657
65CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.17380731
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.13978549
67FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.12165210
68GATA4_25053715_ChIP-Seq_YYC3_Human1.11490632
69STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.10691313
70FOXA1_25552417_ChIP-Seq_VCAP_Human1.10676017
71ESR1_20079471_ChIP-ChIP_T-47D_Human1.10582971
72TP63_23658742_ChIP-Seq_EP156T_Human1.09525232
73ESR1_21235772_ChIP-Seq_MCF-7_Human1.09352875
74AHR_22903824_ChIP-Seq_MCF-7_Human1.09152139
75GATA2_21666600_ChIP-Seq_HMVEC_Human1.07949121
76ARNT_22903824_ChIP-Seq_MCF-7_Human1.07511398
77ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.06807245
78TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05640813
79BCAT_22108803_ChIP-Seq_LS180_Human1.05483775
80RXR_22108803_ChIP-Seq_LS180_Human1.05447913
81HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.05342079
82EGR1_19374776_ChIP-ChIP_THP-1_Human1.04738629
83SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04733769
84CDX2_22108803_ChIP-Seq_LS180_Human1.04614322
85FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03434518
86FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03368070
87TAF15_26573619_Chip-Seq_HEK293_Human1.02859396
88TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.02483314
89CDX2_20551321_ChIP-Seq_CACO-2_Human1.01228928
90MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.00674704
91BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.00529732
92TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.00477464
93NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.00402859
94TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.99825396
95ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.99414501
96RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99325363
97GATA3_24758297_ChIP-Seq_MCF-7_Human0.99276100
98YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99153154
99ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98923040
100ZFP57_27257070_Chip-Seq_ESCs_Mouse0.98704423
101HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.98544012
102SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.97426341
103ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.97219016
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96620237
105NANOG_18555785_Chip-Seq_ESCs_Mouse0.96592990
106NFIB_24661679_ChIP-Seq_LUNG_Mouse0.96564959
107PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.96277936
108PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.95399459
109WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.94734678
110POU3F2_20337985_ChIP-ChIP_501MEL_Human0.94720564
111SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.93901017
112NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93893967
113ZFX_18555785_ChIP-Seq_MESCs_Mouse0.93485575
114SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.93476845
115NR3C1_23031785_ChIP-Seq_PC12_Mouse0.93147438
116JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93042690
117TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92680286
118NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.92322269
119SMAD3_21741376_ChIP-Seq_EPCs_Human0.92204598
120VDR_24787735_ChIP-Seq_THP-1_Human0.90799624
121FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.90279705
122IRF8_27001747_Chip-Seq_BMDM_Mouse0.89765571
123CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.89172063
124TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88459593
125WT1_25993318_ChIP-Seq_PODOCYTE_Human0.88375077
126MTF2_20144788_ChIP-Seq_MESCs_Mouse0.88281610
127RARG_19884340_ChIP-ChIP_MEFs_Mouse0.86643388
128RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.86254671
129P300_27058665_Chip-Seq_ZR-75-30cells_Human0.85878935
130GBX2_23144817_ChIP-Seq_PC3_Human0.84454253
131PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.82892483
132PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.82240825
133SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.81543239
134SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.81543239
135GATA1_19941826_ChIP-Seq_K562_Human0.80777958
136SOX2_21211035_ChIP-Seq_LN229_Gbm0.78972780
137STAT3_23295773_ChIP-Seq_U87_Human0.78605982
138CTNNB1_20460455_ChIP-Seq_HCT116_Human0.78525489
139TBX20_22328084_ChIP-Seq_HEART_Mouse0.78351785

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.22809899
2MP0005360_urolithiasis4.18183299
3MP0010234_abnormal_vibrissa_follicle3.25914481
4MP0005085_abnormal_gallbladder_physiolo3.22371510
5MP0008438_abnormal_cutaneous_collagen3.14035303
6MP0003300_gastrointestinal_ulcer3.13139644
7MP0005365_abnormal_bile_salt3.08679506
8MP0003252_abnormal_bile_duct3.00054028
9MP0003195_calcinosis2.93625422
10MP0003705_abnormal_hypodermis_morpholog2.84597886
11MP0003941_abnormal_skin_development2.78767796
12MP0001666_abnormal_nutrient_absorption2.43189203
13MP0008875_abnormal_xenobiotic_pharmacok2.26103286
14MP0010678_abnormal_skin_adnexa2.25587861
15MP0005058_abnormal_lysosome_morphology2.20572510
16MP0009384_cardiac_valve_regurgitation2.05639211
17MP0003690_abnormal_glial_cell1.97732227
18MP0009780_abnormal_chondrocyte_physiolo1.96981886
19MP0000920_abnormal_myelination1.86321127
20MP0002877_abnormal_melanocyte_morpholog1.84416688
21MP0005083_abnormal_biliary_tract1.82278921
22MP0010329_abnormal_lipoprotein_level1.79247209
23MP0009840_abnormal_foam_cell1.76713756
24MP0003191_abnormal_cellular_cholesterol1.75066189
25MP0004043_abnormal_pH_regulation1.69162523
26MP0004272_abnormal_basement_membrane1.68123617
27MP0002138_abnormal_hepatobiliary_system1.67805659
28MP0010368_abnormal_lymphatic_system1.62510117
29MP0005275_abnormal_skin_tensile1.60514292
30MP0000604_amyloidosis1.57920268
31MP0000383_abnormal_hair_follicle1.54251357
32MP0005023_abnormal_wound_healing1.49498055
33MP0006054_spinal_hemorrhage1.48532305
34MP0003868_abnormal_feces_composition1.46966380
35MP0002896_abnormal_bone_mineralization1.44804905
36MP0002118_abnormal_lipid_homeostasis1.40635340
37MP0005332_abnormal_amino_acid1.38922543
38MP0005409_darkened_coat_color1.34195349
39MP0005220_abnormal_exocrine_pancreas1.29745742
40MP0003329_amyloid_beta_deposits1.28732986
41MP0003279_aneurysm1.27805283
42MP0003806_abnormal_nucleotide_metabolis1.27010387
43MP0009643_abnormal_urine_homeostasis1.26012397
44MP0000462_abnormal_digestive_system1.24812894
45MP0003172_abnormal_lysosome_physiology1.24656700
46MP0009697_abnormal_copulation1.24073147
47MP0002295_abnormal_pulmonary_circulatio1.23847809
48MP0001915_intracranial_hemorrhage1.21178522
49MP0005623_abnormal_meninges_morphology1.21098429
50MP0000762_abnormal_tongue_morphology1.19045715
51MP0000013_abnormal_adipose_tissue1.18869736
52MP0004185_abnormal_adipocyte_glucose1.18129402
53MP0000609_abnormal_liver_physiology1.14946912
54MP0003283_abnormal_digestive_organ1.13135998
55MP0001958_emphysema1.12601953
56MP0001299_abnormal_eye_distance/1.10697620
57MP0003566_abnormal_cell_adhesion1.08247715
58MP0002254_reproductive_system_inflammat1.07475895
59MP0004019_abnormal_vitamin_homeostasis1.04604805
60MP0000767_abnormal_smooth_muscle1.02754537
61MP0005408_hypopigmentation1.00453654
62MP0002060_abnormal_skin_morphology1.00229777
63MP0003453_abnormal_keratinocyte_physiol0.99706096
64MP0001944_abnormal_pancreas_morphology0.99699641
65MP0003075_altered_response_to0.98966122
66MP0004233_abnormal_muscle_weight0.97541669
67MP0003385_abnormal_body_wall0.96690231
68MP0003183_abnormal_peptide_metabolism0.94657121
69MP0000003_abnormal_adipose_tissue0.94276464
70MP0003091_abnormal_cell_migration0.93837920
71MP0002090_abnormal_vision0.93802951
72MP0005584_abnormal_enzyme/coenzyme_acti0.93469640
73MP0002009_preneoplasia0.93019209
74MP0004885_abnormal_endolymph0.92447729
75MP0003950_abnormal_plasma_membrane0.92274885
76MP0000537_abnormal_urethra_morphology0.91961217
77MP0001765_abnormal_ion_homeostasis0.91731218
78MP0005197_abnormal_uvea_morphology0.91639555
79MP0003634_abnormal_glial_cell0.90419406
80MP0003890_abnormal_embryonic-extraembry0.88338381
81MP0003221_abnormal_cardiomyocyte_apopto0.86338811
82MP0002909_abnormal_adrenal_gland0.86205149
83MP0003045_fibrosis0.85690722
84MP0005164_abnormal_response_to0.85227363
85MP0001243_abnormal_dermal_layer0.84578472
86MP0010352_gastrointestinal_tract_polyps0.84032342
87MP0003303_peritoneal_inflammation0.83892020
88MP0005165_increased_susceptibility_to0.83873810
89MP0004782_abnormal_surfactant_physiolog0.83598677
90MP0001542_abnormal_bone_strength0.82534119
91MP0002928_abnormal_bile_duct0.81899816
92MP0005451_abnormal_body_composition0.80989377
93MP0004264_abnormal_extraembryonic_tissu0.80654075
94MP0002078_abnormal_glucose_homeostasis0.79975175
95MP0004130_abnormal_muscle_cell0.79788363
96MP0005187_abnormal_penis_morphology0.79629488
97MP0005508_abnormal_skeleton_morphology0.79619707
98MP0001177_atelectasis0.79468943
99MP0000427_abnormal_hair_cycle0.79052838
100MP0001216_abnormal_epidermal_layer0.79037241
101MP0002269_muscular_atrophy0.78763860
102MP0003656_abnormal_erythrocyte_physiolo0.77344478
103MP0002693_abnormal_pancreas_physiology0.76439427
104MP0000627_abnormal_mammary_gland0.75112464
105MP0010386_abnormal_urinary_bladder0.74016528
106MP0005621_abnormal_cell_physiology0.73905828
107MP0002086_abnormal_extraembryonic_tissu0.73784699
108MP0009053_abnormal_anal_canal0.73028104
109MP0004947_skin_inflammation0.72724217
110MP0002168_other_aberrant_phenotype0.72657643
111MP0000534_abnormal_ureter_morphology0.72218026
112MP0002697_abnormal_eye_size0.71894726
113MP0000377_abnormal_hair_follicle0.71630834
114MP0001756_abnormal_urination0.71589027
115MP0000569_abnormal_digit_pigmentation0.71298148
116MP0000467_abnormal_esophagus_morphology0.71295353
117MP0000432_abnormal_head_morphology0.71229023
118MP0005248_abnormal_Harderian_gland0.70969513
119MP0003937_abnormal_limbs/digits/tail_de0.70587248
120MP0001849_ear_inflammation0.69927508
121MP0000428_abnormal_craniofacial_morphol0.69812764
122MP0004134_abnormal_chest_morphology0.69040072
123MP0002084_abnormal_developmental_patter0.67785815
124MP0000733_abnormal_muscle_development0.67486295
125MP0001661_extended_life_span0.67365192
126MP0002796_impaired_skin_barrier0.66868015
127MP0008004_abnormal_stomach_pH0.66731287
128MP0000465_gastrointestinal_hemorrhage0.66485196
129MP0005319_abnormal_enzyme/_coenzyme0.66437148
130MP0001879_abnormal_lymphatic_vessel0.66391282
131MP0005501_abnormal_skin_physiology0.66327367
132MP0002166_altered_tumor_susceptibility0.65662427
133MP0002998_abnormal_bone_remodeling0.65308600
134MP0005375_adipose_tissue_phenotype0.65174238
135MP0006082_CNS_inflammation0.64777457
136MP0005193_abnormal_anterior_eye0.64756859
137MP0002092_abnormal_eye_morphology0.63862343
138MP0001881_abnormal_mammary_gland0.63032505
139MP0005257_abnormal_intraocular_pressure0.62898755
140MP0003755_abnormal_palate_morphology0.61930419
141MP0004484_altered_response_of0.61696826
142MP0002098_abnormal_vibrissa_morphology0.61251831
143MP0000579_abnormal_nail_morphology0.61167937
144MP0005503_abnormal_tendon_morphology0.60366968
145MP0005636_abnormal_mineral_homeostasis0.60163058
146MP0000647_abnormal_sebaceous_gland0.60021111
147MP0010771_integument_phenotype0.59633966
148MP0003632_abnormal_nervous_system0.59365277
149MP0002136_abnormal_kidney_physiology0.58942290

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)4.37796714
2Deep venous thrombosis (HP:0002625)4.19288328
3Protrusio acetabuli (HP:0003179)3.94580250
4Xanthomatosis (HP:0000991)3.74204940
5Abnormality of aromatic amino acid family metabolism (HP:0004338)3.53008877
6Atrophic scars (HP:0001075)3.34911273
7Abnormality of the common coagulation pathway (HP:0010990)3.32628693
8Neurofibrillary tangles (HP:0002185)3.31895739
9Complement deficiency (HP:0004431)3.20693771
10Hypoglycemic coma (HP:0001325)3.19694007
11Hypoglycemic seizures (HP:0002173)3.05264890
12Cerebral inclusion bodies (HP:0100314)3.01436408
13Abnormality of the intrinsic pathway (HP:0010989)3.01089223
14Abnormality of monocarboxylic acid metabolism (HP:0010996)2.93718202
15Ketoacidosis (HP:0001993)2.88255695
16Epidermoid cyst (HP:0200040)2.87080891
17Hyperinsulinemic hypoglycemia (HP:0000825)2.84007807
18Papillary thyroid carcinoma (HP:0002895)2.80720239
19Ankle contracture (HP:0006466)2.76884647
20Tetraparesis (HP:0002273)2.76585888
21Dysostosis multiplex (HP:0000943)2.72728571
22Hyperlipoproteinemia (HP:0010980)2.72704237
23Abnormality of dentin (HP:0010299)2.69380293
24Short nail (HP:0001799)2.68948673
25Ketosis (HP:0001946)2.65195488
26Prolonged partial thromboplastin time (HP:0003645)2.64580619
27Fat malabsorption (HP:0002630)2.64420857
28Right ventricular cardiomyopathy (HP:0011663)2.60441354
29Premature rupture of membranes (HP:0001788)2.59262324
30Cervical subluxation (HP:0003308)2.58861847
31Wormian bones (HP:0002645)2.57839366
32Urinary glycosaminoglycan excretion (HP:0003541)2.57518924
33Mucopolysacchariduria (HP:0008155)2.57518924
34Vascular calcification (HP:0004934)2.49866133
35Vertebral compression fractures (HP:0002953)2.49081407
36Macroorchidism (HP:0000053)2.48459594
37Hypobetalipoproteinemia (HP:0003563)2.46756290
38Conjugated hyperbilirubinemia (HP:0002908)2.43620310
39Back pain (HP:0003418)2.43169456
40Skin nodule (HP:0200036)2.38192227
41Myocardial infarction (HP:0001658)2.36863886
42Termporal pattern (HP:0011008)2.36421426
43Insidious onset (HP:0003587)2.36421426
44Asymmetry of the thorax (HP:0001555)2.36140661
45Symptomatic seizures (HP:0011145)2.35575936
46Turricephaly (HP:0000262)2.35030897
47Abnormality of glutamine family amino acid metabolism (HP:0010902)2.34904751
48Abnormality of mucopolysaccharide metabolism (HP:0011020)2.33712529
49Abnormality of polysaccharide metabolism (HP:0011012)2.33712529
50Abnormality of glycosaminoglycan metabolism (HP:0004371)2.33712529
51Follicular hyperkeratosis (HP:0007502)2.31957794
52Aortic aneurysm (HP:0004942)2.29624839
53Protuberant abdomen (HP:0001538)2.28417811
54Buphthalmos (HP:0000557)2.26028732
55Abnormality of complement system (HP:0005339)2.21023067
56Ankyloglossia (HP:0010296)2.20336499
57Soft skin (HP:0000977)2.19658866
58Thyroid carcinoma (HP:0002890)2.18428816
59Hematochezia (HP:0002573)2.18070408
60Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.16700502
61Fragile skin (HP:0001030)2.16445185
62Joint hemorrhage (HP:0005261)2.16104445
63Pterygium (HP:0001059)2.15159029
64Degeneration of the lateral corticospinal tracts (HP:0002314)2.14240250
65Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.14240250
66Spastic diplegia (HP:0001264)2.12885251
67Abnormality of sulfur amino acid metabolism (HP:0004339)2.12553540
68Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.10423833
69Hypolipoproteinemia (HP:0010981)2.08963052
70Hepatocellular carcinoma (HP:0001402)2.08931504
71Increased cerebral lipofuscin (HP:0011813)2.07399924
72Intention tremor (HP:0002080)2.03861284
73Flat acetabular roof (HP:0003180)2.03591505
74Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.03063483
75Abnormal delivery (HP:0001787)2.02966830
76Hypoalphalipoproteinemia (HP:0003233)2.01623825
77Coronal craniosynostosis (HP:0004440)2.01122226
78Vertebral arch anomaly (HP:0008438)1.99530838
79Abdominal distention (HP:0003270)1.99513033
80Abnormality of carpal bone ossification (HP:0006257)1.99087320
81Increased CSF protein (HP:0002922)1.98417826
82Peritonitis (HP:0002586)1.97689733
83Epiphyseal dysplasia (HP:0002656)1.97202049
84Abnormality of aspartate family amino acid metabolism (HP:0010899)1.96911243
85Osteolytic defects of the phalanges of the hand (HP:0009771)1.96457862
86Osteolytic defects of the hand bones (HP:0009699)1.96457862
87Pheochromocytoma (HP:0002666)1.96346470
88Subacute progressive viral hepatitis (HP:0006572)1.96229353
89Peripheral demyelination (HP:0011096)1.95401565
90Mitral valve prolapse (HP:0001634)1.93813109
91Abnormality of oral frenula (HP:0000190)1.93313709
92Thin bony cortex (HP:0002753)1.92990338
93Abnormality of the acetabulum (HP:0003170)1.92813498
94Hypophosphatemic rickets (HP:0004912)1.92780112
95Increased circulating renin level (HP:0000848)1.92349412
96Hyperextensible skin (HP:0000974)1.91022238
97Focal segmental glomerulosclerosis (HP:0000097)1.90858068
98Arterial tortuosity (HP:0005116)1.90309302
99Spinal rigidity (HP:0003306)1.89023172
100Retinal atrophy (HP:0001105)1.88610912
101Cerebral aneurysm (HP:0004944)1.88052773
102Abnormality of the pancreatic islet cells (HP:0006476)1.87316066
103Abnormality of endocrine pancreas physiology (HP:0012093)1.87316066
104Esophageal varix (HP:0002040)1.86232099
105Bladder diverticulum (HP:0000015)1.86113019
106Aortic dissection (HP:0002647)1.84754247
107Orthostatic hypotension (HP:0001278)1.84124757
108Hyperglycemia (HP:0003074)1.83757078
109Mildly elevated creatine phosphokinase (HP:0008180)1.83703340
110Microglossia (HP:0000171)1.83518113
111Hemorrhage of the eye (HP:0011885)1.83445881
112Overgrowth (HP:0001548)1.83344040
113Glomerulosclerosis (HP:0000096)1.82707368
114Glomerulonephritis (HP:0000099)1.82501396
115Vacuolated lymphocytes (HP:0001922)1.81563092
116Mitral stenosis (HP:0001718)1.80678351
117Syringomyelia (HP:0003396)1.80614040
118Spinal cord lesions (HP:0100561)1.80614040
119Steatorrhea (HP:0002570)1.80345134
120Amyloidosis (HP:0011034)1.80015329
121Pancreatic islet-cell hyperplasia (HP:0004510)1.79346522
122Dilatation of the ascending aorta (HP:0005111)1.79204008
123Absent frontal sinuses (HP:0002688)1.78956027
124Abnormality of proline metabolism (HP:0010907)1.78467545
125Hydroxyprolinuria (HP:0003080)1.78467545
126Abnormality of the distal phalanges of the toes (HP:0010182)1.78159308
127Blue sclerae (HP:0000592)1.78016676
128Abnormality of purine metabolism (HP:0004352)1.77589529
129Vascular tortuosity (HP:0004948)1.77582620
130Hypokalemic alkalosis (HP:0001949)1.77162571
131Visceral angiomatosis (HP:0100761)1.76983014
132Cardiovascular calcification (HP:0011915)1.75450469
133Abnormality of the lumbar spine (HP:0100712)1.73433880
134Increased neuronal autofluorescent lipopigment (HP:0002074)1.73300698
135Shallow orbits (HP:0000586)1.73210087
136Abnormality of methionine metabolism (HP:0010901)1.72957111
137Relative macrocephaly (HP:0004482)1.72775756
138Hypercholesterolemia (HP:0003124)1.71952798
139Congenital glaucoma (HP:0001087)1.71514331
140Broad metatarsal (HP:0001783)1.70697151
141Femoral bowing (HP:0002980)1.70278033
142Axonal loss (HP:0003447)1.69514987
143Advanced eruption of teeth (HP:0006288)1.68873611
144Spondylolisthesis (HP:0003302)1.68867574
145Natal tooth (HP:0000695)1.68462397
146Abnormal foot bone ossification (HP:0010675)1.66540801
147Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.64960794
148Long toe (HP:0010511)1.64563968
149Breech presentation (HP:0001623)1.64266014
150Abnormal ossification of hand bones (HP:0005921)1.63393331
151Osteopenia (HP:0000938)1.62807390
152Proximal tubulopathy (HP:0000114)1.60810463
153Ovoid vertebral bodies (HP:0003300)1.60539760
154Pulmonic stenosis (HP:0001642)1.60374309
155Limb-girdle muscle atrophy (HP:0003797)1.60035385
156Limb-girdle muscle weakness (HP:0003325)1.59291863
157Chondrocalcinosis (HP:0000934)1.58609565
158Periodontitis (HP:0000704)1.58597944
159Aneurysm (HP:0002617)1.57603442
160Elbow flexion contracture (HP:0002987)1.57106187
161Knee flexion contracture (HP:0006380)1.55630055
162Wrist flexion contracture (HP:0001239)1.55071089
163Glucose intolerance (HP:0000833)1.54790838

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.03724567
2FRK2.95041186
3PKN22.93692672
4TRIB32.75403125
5FGFR22.64432121
6EPHB12.62314572
7MAP3K22.54857029
8ERBB32.50225386
9SCYL22.48478264
10INSRR2.39471158
11TAOK32.37830718
12PTK62.33904779
13MET2.25358715
14EIF2AK32.19243196
15LATS12.10507146
16LATS22.08821987
17EPHA22.01847917
18OXSR11.90260267
19RIPK11.84405370
20WNK41.82399394
21SIK11.81954031
22PDGFRA1.81793847
23PAK41.80159603
24EIF2AK11.78484447
25DDR21.73896152
26MAP3K61.70591650
27ERN11.67436894
28STK38L1.67380222
29LMTK21.59566108
30MYLK1.57892502
31MST1R1.53188306
32TSSK61.50039025
33TESK11.43126114
34NEK11.40992775
35NTRK11.40791199
36AKT31.35506736
37CAMK1D1.33718909
38RET1.26657913
39ERBB41.24736372
40MAP3K121.23587960
41PAK31.20506413
42BRSK21.20287193
43CAMK1G1.19815937
44FGFR41.19364135
45PDGFRB1.19109398
46PTK21.18637982
47BMPR21.18047512
48MAPK151.15427237
49JAK11.14696440
50TRIM281.14365900
51KSR21.12459819
52YES11.11215698
53TTN1.09047158
54STK241.08527183
55TGFBR21.07263756
56CSNK1A1L1.06235242
57WNK11.05589747
58HIPK21.04324783
59TTK1.03797628
60MST41.02584737
61TAF11.02359157
62EPHA31.02282570
63FLT31.01179681
64LRRK21.00559082
65PLK20.98618923
66GSK3A0.96219720
67IRAK30.95276364
68PBK0.94910747
69PKN10.92751510
70JAK20.92540798
71FGR0.91022964
72KSR10.90448739
73PAK20.89798089
74PDPK10.89749931
75BMX0.88620601
76NEK90.87776210
77TRPM70.86241991
78BCR0.86017329
79BRD40.83901108
80FGFR10.82497719
81STK380.82001077
82EPHB20.81159431
83CSK0.80396170
84DYRK1B0.79238679
85PRKCH0.78503555
86MAP3K30.78356288
87FER0.77441486
88CAMKK10.76456859
89MOS0.75792912
90MAP3K10.73012629
91CDK60.72595824
92STK30.72419463
93PDK10.72327773
94PRKD10.71853106
95PRKG20.70978374
96CSNK1G20.69680707
97LIMK10.68946763
98MAP3K90.66688797
99FGFR30.66453793
100PLK30.66077580
101CAMKK20.63719265
102ICK0.63223971
103INSR0.62631292
104TYK20.62264671
105PRKCQ0.62169695
106EGFR0.61776825
107ITK0.61691486
108NUAK10.60643201
109MAPKAPK50.57850449
110CSNK1G10.56182200
111DMPK0.56027541
112RPS6KA40.55545110
113TYRO30.54956585
114IGF1R0.54274088
115SRPK10.53853175
116NEK60.53511416
117PRKCE0.52271342
118FYN0.52267897
119PASK0.52213956
120WNK30.50280658
121PIK3CA0.50188104
122ERBB20.47222043
123CSNK1G30.46564502
124STK100.46222927
125MAP3K50.45955599
126CAMK2B0.44772635
127CSF1R0.43963821
128MELK0.42450989
129JAK30.42428941
130ABL10.42350155
131AKT20.42117288
132SRC0.42100791
133EEF2K0.41827312
134EIF2AK20.41155753
135ROCK20.40580414
136CASK0.39615350
137TBK10.38568653
138MAP2K20.38478706
139CAMK2D0.38156784
140ROCK10.33000598
141MAP3K80.32624725
142ARAF0.32608661
143PIK3CG0.28906678
144MAP3K40.27335970
145DYRK30.26210517
146CAMK2G0.25527605
147RAF10.24741937

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.83981224
2Sulfur metabolism_Homo sapiens_hsa009202.77905422
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.50969265
4Primary bile acid biosynthesis_Homo sapiens_hsa001202.46484918
5Vitamin B6 metabolism_Homo sapiens_hsa007502.40008390
6Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.91529976
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.88648548
8Steroid biosynthesis_Homo sapiens_hsa001001.79472350
9Complement and coagulation cascades_Homo sapiens_hsa046101.77917550
10Butanoate metabolism_Homo sapiens_hsa006501.77674840
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.69390998
12Tryptophan metabolism_Homo sapiens_hsa003801.67428275
13Arginine biosynthesis_Homo sapiens_hsa002201.63567688
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59886024
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.54630244
16Fatty acid degradation_Homo sapiens_hsa000711.54499875
17Bile secretion_Homo sapiens_hsa049761.49051660
18Selenocompound metabolism_Homo sapiens_hsa004501.46877096
19Histidine metabolism_Homo sapiens_hsa003401.42912411
20Fatty acid metabolism_Homo sapiens_hsa012121.32222127
21Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.31326254
22Caffeine metabolism_Homo sapiens_hsa002321.30456340
23PPAR signaling pathway_Homo sapiens_hsa033201.27709565
24Fatty acid elongation_Homo sapiens_hsa000621.27483134
25Staphylococcus aureus infection_Homo sapiens_hsa051501.26888165
26Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.26312885
27Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.24438984
28Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.21263587
29Propanoate metabolism_Homo sapiens_hsa006401.20133115
30Thyroid cancer_Homo sapiens_hsa052161.18228779
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.16863106
32ABC transporters_Homo sapiens_hsa020101.13858646
33Central carbon metabolism in cancer_Homo sapiens_hsa052301.13436754
34Lysosome_Homo sapiens_hsa041421.12857315
35Small cell lung cancer_Homo sapiens_hsa052221.12609531
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.12575454
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.10705173
38Fat digestion and absorption_Homo sapiens_hsa049751.10224481
39Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.08644305
40Other glycan degradation_Homo sapiens_hsa005111.08190917
41Peroxisome_Homo sapiens_hsa041461.06607613
42Galactose metabolism_Homo sapiens_hsa000521.06049873
43Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.03686289
44Hippo signaling pathway_Homo sapiens_hsa043901.02415249
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01009674
46TGF-beta signaling pathway_Homo sapiens_hsa043500.99240930
47ECM-receptor interaction_Homo sapiens_hsa045120.97868324
48Folate biosynthesis_Homo sapiens_hsa007900.97555756
49Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.96213466
50Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.95738840
51Carbon metabolism_Homo sapiens_hsa012000.94369626
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.92145249
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90237249
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89787314
55Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.89465582
56Biosynthesis of amino acids_Homo sapiens_hsa012300.89013554
57Circadian rhythm_Homo sapiens_hsa047100.88536977
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.87932474
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87576440
60Starch and sucrose metabolism_Homo sapiens_hsa005000.87485058
61Prion diseases_Homo sapiens_hsa050200.86359264
62Fructose and mannose metabolism_Homo sapiens_hsa000510.85609347
63Chemical carcinogenesis_Homo sapiens_hsa052040.83962961
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.81439728
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78325875
66Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76515352
67Focal adhesion_Homo sapiens_hsa045100.76274660
68Dorso-ventral axis formation_Homo sapiens_hsa043200.75679118
69Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75103955
70Type II diabetes mellitus_Homo sapiens_hsa049300.73826605
71beta-Alanine metabolism_Homo sapiens_hsa004100.73549285
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.72348158
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72151123
74Protein digestion and absorption_Homo sapiens_hsa049740.71895647
75Vitamin digestion and absorption_Homo sapiens_hsa049770.70827561
76Amoebiasis_Homo sapiens_hsa051460.70367918
77Renal cell carcinoma_Homo sapiens_hsa052110.68917448
78PI3K-Akt signaling pathway_Homo sapiens_hsa041510.68508667
79Thyroid hormone synthesis_Homo sapiens_hsa049180.67973085
80Insulin resistance_Homo sapiens_hsa049310.66330380
81Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64497808
82Glycosaminoglycan degradation_Homo sapiens_hsa005310.64261677
83Pentose phosphate pathway_Homo sapiens_hsa000300.63007238
84Dilated cardiomyopathy_Homo sapiens_hsa054140.62666503
85MicroRNAs in cancer_Homo sapiens_hsa052060.61582297
86Lysine degradation_Homo sapiens_hsa003100.61400315
87Proteoglycans in cancer_Homo sapiens_hsa052050.61150750
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60310196
89Retinol metabolism_Homo sapiens_hsa008300.60073480
90Fatty acid biosynthesis_Homo sapiens_hsa000610.57533522
91Endometrial cancer_Homo sapiens_hsa052130.57446095
92Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.56185096
93Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56129252
94Phenylalanine metabolism_Homo sapiens_hsa003600.56067055
95Arginine and proline metabolism_Homo sapiens_hsa003300.54894811
96Mineral absorption_Homo sapiens_hsa049780.54726886
97Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.54027459
98Glucagon signaling pathway_Homo sapiens_hsa049220.53286054
99Pancreatic secretion_Homo sapiens_hsa049720.52931932
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.52225281
101Protein export_Homo sapiens_hsa030600.52065535
102Inositol phosphate metabolism_Homo sapiens_hsa005620.51986392
103Sphingolipid metabolism_Homo sapiens_hsa006000.51567632
104Gap junction_Homo sapiens_hsa045400.51238999
105Tyrosine metabolism_Homo sapiens_hsa003500.50195132
106Glutathione metabolism_Homo sapiens_hsa004800.48572552
107Adipocytokine signaling pathway_Homo sapiens_hsa049200.48364829
108Ether lipid metabolism_Homo sapiens_hsa005650.47782079
109Cysteine and methionine metabolism_Homo sapiens_hsa002700.47725849
110p53 signaling pathway_Homo sapiens_hsa041150.44160766
111Estrogen signaling pathway_Homo sapiens_hsa049150.42769710
112Tight junction_Homo sapiens_hsa045300.42288063
113Renin-angiotensin system_Homo sapiens_hsa046140.42004528
114Malaria_Homo sapiens_hsa051440.41663146
115Bladder cancer_Homo sapiens_hsa052190.40903918
116Adherens junction_Homo sapiens_hsa045200.39601600
117Pancreatic cancer_Homo sapiens_hsa052120.38390645
118Chronic myeloid leukemia_Homo sapiens_hsa052200.38206840
119Prostate cancer_Homo sapiens_hsa052150.37563862
120Glycerolipid metabolism_Homo sapiens_hsa005610.37420861
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.37348063
122Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37300485
123Phagosome_Homo sapiens_hsa041450.37223344
124Renin secretion_Homo sapiens_hsa049240.34937943
125N-Glycan biosynthesis_Homo sapiens_hsa005100.34167225
126Glioma_Homo sapiens_hsa052140.34005830
127Insulin secretion_Homo sapiens_hsa049110.33387535
128Pyruvate metabolism_Homo sapiens_hsa006200.33244098
129Axon guidance_Homo sapiens_hsa043600.33180147
130Platelet activation_Homo sapiens_hsa046110.33004445
131Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32570309
132Ovarian steroidogenesis_Homo sapiens_hsa049130.31862850
133Endocytosis_Homo sapiens_hsa041440.31684814
134Vibrio cholerae infection_Homo sapiens_hsa051100.31675040
135Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.30682226
136Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.30399952
137AMPK signaling pathway_Homo sapiens_hsa041520.30050309

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