TMEM108

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)5.91332081
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.77821674
3neuron cell-cell adhesion (GO:0007158)5.34747594
4pyrimidine nucleobase catabolic process (GO:0006208)5.20454869
5ionotropic glutamate receptor signaling pathway (GO:0035235)5.15882117
6synaptic transmission, glutamatergic (GO:0035249)4.85125980
7synaptic vesicle docking involved in exocytosis (GO:0016081)4.64459501
8presynaptic membrane assembly (GO:0097105)4.64305732
9glutamate receptor signaling pathway (GO:0007215)4.56845035
10protein localization to synapse (GO:0035418)4.54319596
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.35981351
12neuron recognition (GO:0008038)4.33264011
13presynaptic membrane organization (GO:0097090)4.28762243
14exploration behavior (GO:0035640)4.24644474
15G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.19187748
16nucleobase catabolic process (GO:0046113)4.16437231
17regulation of synaptic vesicle exocytosis (GO:2000300)4.09012080
18regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.08774031
19response to pheromone (GO:0019236)4.07994892
20positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.05543310
21regulation of synaptic vesicle transport (GO:1902803)4.04819566
22neuron-neuron synaptic transmission (GO:0007270)4.03620594
23negative regulation of synaptic transmission, glutamatergic (GO:0051967)4.01568996
24synaptic vesicle exocytosis (GO:0016079)4.01106185
25axonal fasciculation (GO:0007413)3.99265565
26glutamate secretion (GO:0014047)3.94860103
27regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.91712055
28behavioral response to nicotine (GO:0035095)3.88605568
29synaptic vesicle maturation (GO:0016188)3.85384671
30cerebral cortex radially oriented cell migration (GO:0021799)3.82807899
31activated T cell proliferation (GO:0050798)3.75454970
32dendrite morphogenesis (GO:0048813)3.72484483
33vocalization behavior (GO:0071625)3.71568088
34negative regulation of axon guidance (GO:1902668)3.64019689
35pyrimidine dimer repair (GO:0006290)3.61724138
36regulation of glutamate receptor signaling pathway (GO:1900449)3.56744041
37postsynaptic membrane organization (GO:0001941)3.55958956
38auditory behavior (GO:0031223)3.51558295
39transmission of nerve impulse (GO:0019226)3.50554891
40negative regulation of axon extension involved in axon guidance (GO:0048843)3.50148843
41long-term memory (GO:0007616)3.45162092
42neuromuscular synaptic transmission (GO:0007274)3.42723127
43regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.40220926
44synapse assembly (GO:0007416)3.38251565
45regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.37883675
46regulation of axon guidance (GO:1902667)3.37543122
47positive regulation of actin filament depolymerization (GO:0030836)3.33314908
48long-term synaptic potentiation (GO:0060291)3.32556858
49neurotransmitter-gated ion channel clustering (GO:0072578)3.32262173
50central nervous system projection neuron axonogenesis (GO:0021952)3.31175301
51positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.30900218
52amino acid import (GO:0043090)3.29707295
53regulation of synaptic transmission, glutamatergic (GO:0051966)3.28509049
54regulation of axon extension involved in axon guidance (GO:0048841)3.25690405
55negative regulation of axon extension (GO:0030517)3.25558948
56positive regulation of synapse maturation (GO:0090129)3.20678746
57cellular sodium ion homeostasis (GO:0006883)3.18436655
58mechanosensory behavior (GO:0007638)3.18386280
59innervation (GO:0060384)3.12488425
60cerebellar granule cell differentiation (GO:0021707)3.11202120
61gamma-aminobutyric acid signaling pathway (GO:0007214)3.06979789
62behavioral fear response (GO:0001662)3.06502699
63behavioral defense response (GO:0002209)3.06502699
64regulation of neuronal synaptic plasticity (GO:0048168)3.05075884
65cerebellar Purkinje cell differentiation (GO:0021702)3.04068635
66positive regulation of synapse assembly (GO:0051965)3.02986000
67positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.02812412
68sympathetic nervous system development (GO:0048485)3.02679929
69negative regulation of synaptic transmission, GABAergic (GO:0032229)3.02604664
70neurotransmitter secretion (GO:0007269)3.01487525
71regulation of vesicle fusion (GO:0031338)2.98763208
72regulation of respiratory system process (GO:0044065)2.98016455
73neuronal action potential (GO:0019228)2.97960136
74negative regulation of cytosolic calcium ion concentration (GO:0051481)2.97732039
75regulation of neurotransmitter secretion (GO:0046928)2.97630806
76regulation of excitatory postsynaptic membrane potential (GO:0060079)2.96687073
77positive regulation of dendritic spine morphogenesis (GO:0061003)2.96484017
78L-amino acid import (GO:0043092)2.95742433
79limb bud formation (GO:0060174)2.94482231
80regulation of postsynaptic membrane potential (GO:0060078)2.94390426
81establishment of mitochondrion localization (GO:0051654)2.92477208
82fear response (GO:0042596)2.92000164
83regulation of synapse structural plasticity (GO:0051823)2.91322730
84membrane hyperpolarization (GO:0060081)2.91178994
85calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.90638969
86retinal ganglion cell axon guidance (GO:0031290)2.90379086
87neuronal ion channel clustering (GO:0045161)2.89412275
88axon ensheathment in central nervous system (GO:0032291)2.86476466
89central nervous system myelination (GO:0022010)2.86476466
90retinal cone cell development (GO:0046549)2.85739252
91dendritic spine morphogenesis (GO:0060997)2.85244701
92positive regulation of synaptic transmission, GABAergic (GO:0032230)2.85134306
93regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.85133459
94response to redox state (GO:0051775)2.84250829
95neuronal action potential propagation (GO:0019227)2.83972146
96negative regulation of axonogenesis (GO:0050771)2.83717997
97opioid receptor signaling pathway (GO:0038003)2.83050712
98negative regulation of neurotransmitter secretion (GO:0046929)2.81594934
99adult walking behavior (GO:0007628)2.78762817
100behavioral response to ethanol (GO:0048149)2.78392513
101response to auditory stimulus (GO:0010996)2.77689567
102regulation of respiratory gaseous exchange (GO:0043576)2.75503752
103positive regulation of membrane potential (GO:0045838)2.74846931
104positive regulation of meiosis (GO:0045836)2.74427183
105glycosphingolipid biosynthetic process (GO:0006688)2.73072806
106spinal cord development (GO:0021510)2.72595050
107membrane depolarization during action potential (GO:0086010)2.72091804
108cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.71889496
109negative regulation of astrocyte differentiation (GO:0048712)2.70555745
110cell communication by electrical coupling (GO:0010644)2.70149558
111regulation of synaptic plasticity (GO:0048167)2.69938094
112regulation of dendritic spine morphogenesis (GO:0061001)2.69281631
113regulation of neurotransmitter transport (GO:0051588)2.67914826
114startle response (GO:0001964)2.67812854
115positive regulation of potassium ion transmembrane transport (GO:1901381)2.67695407
116regulation of long-term neuronal synaptic plasticity (GO:0048169)2.67496225
117urinary tract smooth muscle contraction (GO:0014848)2.66722275
118regulation of calcium ion-dependent exocytosis (GO:0017158)2.66689857
119regulation of synapse assembly (GO:0051963)2.65498769
120central nervous system neuron axonogenesis (GO:0021955)2.63596490
121regulation of synapse maturation (GO:0090128)2.63550495
122cell migration in hindbrain (GO:0021535)2.63331203
123gamma-aminobutyric acid transport (GO:0015812)2.62930557
124dendrite development (GO:0016358)2.62767904
125calcium ion import (GO:0070509)2.62765007
126learning (GO:0007612)2.61511842
127epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.60763380
128membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.60660596
129synaptic vesicle endocytosis (GO:0048488)2.59742364
130synapse organization (GO:0050808)2.56593516
131hippocampus development (GO:0021766)2.55853336
132regulation of dendritic spine development (GO:0060998)2.47381091
133cerebral cortex cell migration (GO:0021795)2.46101964
134synaptic transmission, cholinergic (GO:0007271)2.44504135
135adult behavior (GO:0030534)2.44184988
136membrane depolarization (GO:0051899)2.43818194
137positive regulation of dendritic spine development (GO:0060999)2.39806128
138short-term memory (GO:0007614)2.38871490
139nonmotile primary cilium assembly (GO:0035058)2.38342177
140behavioral response to cocaine (GO:0048148)2.36531414
141C4-dicarboxylate transport (GO:0015740)2.34446233
142regulation of membrane repolarization (GO:0060306)2.33893744
143regulation of synapse organization (GO:0050807)2.32179766
144regulation of action potential (GO:0098900)2.31926705
145epithelial cilium movement (GO:0003351)2.31915192
146regulation of sarcomere organization (GO:0060297)2.30272065
147positive regulation of potassium ion transport (GO:0043268)2.28183667
148positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.27995271

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.37463666
2GBX2_23144817_ChIP-Seq_PC3_Human4.36762009
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.75305934
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.56677845
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55802441
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.44041241
7* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.34398303
8* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.34398303
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.30359326
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.29975225
11IGF1R_20145208_ChIP-Seq_DFB_Human2.26426878
12REST_21632747_ChIP-Seq_MESCs_Mouse2.24851575
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.19331065
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.19004897
15EZH2_27294783_Chip-Seq_ESCs_Mouse2.18552529
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.18538524
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.16117321
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.10317403
19* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.10209647
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.09494103
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.06312338
22* DROSHA_22980978_ChIP-Seq_HELA_Human2.06049541
23AR_21572438_ChIP-Seq_LNCaP_Human1.94890349
24SUZ12_27294783_Chip-Seq_ESCs_Mouse1.94040681
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.87864105
26RARB_27405468_Chip-Seq_BRAIN_Mouse1.84174259
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.84014612
28* REST_18959480_ChIP-ChIP_MESCs_Mouse1.83466640
29* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.83045993
30* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81903824
31SALL1_21062744_ChIP-ChIP_HESCs_Human1.81728805
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.74968824
33SMAD4_21799915_ChIP-Seq_A2780_Human1.70220426
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.66289902
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.63815887
36NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.61688809
37ZNF274_21170338_ChIP-Seq_K562_Hela1.58283804
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54511545
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.54178995
40SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.48028170
41P300_19829295_ChIP-Seq_ESCs_Human1.47465737
42BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44603898
43* STAT3_23295773_ChIP-Seq_U87_Human1.42890381
44TAF15_26573619_Chip-Seq_HEK293_Human1.42625191
45* SOX2_21211035_ChIP-Seq_LN229_Gbm1.40998283
46POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.40779699
47TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40779699
48UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38459893
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38436151
50PIAS1_25552417_ChIP-Seq_VCAP_Human1.38354786
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.38155008
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36853452
53* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36207335
54* CBP_20019798_ChIP-Seq_JUKART_Human1.36207335
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.36006924
56ER_23166858_ChIP-Seq_MCF-7_Human1.34848897
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.32526600
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.32293419
59RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30976534
60RNF2_27304074_Chip-Seq_NSC_Mouse1.30849202
61TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.30251584
62ZNF217_24962896_ChIP-Seq_MCF-7_Human1.29966793
63CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28847479
64SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28652704
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26465216
66FUS_26573619_Chip-Seq_HEK293_Human1.26398161
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26370692
68* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.25992505
69MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.25277231
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.24428331
71AR_25329375_ChIP-Seq_VCAP_Human1.24413330
72TCF4_23295773_ChIP-Seq_U87_Human1.23032732
73PRDM14_20953172_ChIP-Seq_ESCs_Human1.22966895
74BCAT_22108803_ChIP-Seq_LS180_Human1.22156623
75RING1B_27294783_Chip-Seq_ESCs_Mouse1.22105133
76* AR_19668381_ChIP-Seq_PC3_Human1.20930787
77EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20744446
78NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20514016
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20236323
80TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.19851294
81CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16702810
82EP300_21415370_ChIP-Seq_HL-1_Mouse1.16019638
83IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15931802
84SOX9_26525672_Chip-Seq_HEART_Mouse1.13786880
85* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.13737917
86VDR_22108803_ChIP-Seq_LS180_Human1.13396156
87PCGF2_27294783_Chip-Seq_ESCs_Mouse1.12896014
88POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11595049
89TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11418159
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.11078895
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.10978893
92AHR_22903824_ChIP-Seq_MCF-7_Human1.10457680
93LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09889056
94EWS_26573619_Chip-Seq_HEK293_Human1.09844795
95RING1B_27294783_Chip-Seq_NPCs_Mouse1.09295454
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08861533
97* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08366595
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07097557
99P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06302039
100RUNX2_22187159_ChIP-Seq_PCA_Human1.05175014
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05122743
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04392090
103KDM2B_26808549_Chip-Seq_REH_Human1.03396535
104KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02935273
105* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01540230
106SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01214731
107RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.00895709
108TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.00440243
109TAL1_26923725_Chip-Seq_HPCs_Mouse1.00137708
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99713075
111* TCF4_22108803_ChIP-Seq_LS180_Human0.99634258
112FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99463182
113SMAD_19615063_ChIP-ChIP_OVARY_Human0.99364547
114RBPJ_22232070_ChIP-Seq_NCS_Mouse0.99215113
115P53_22387025_ChIP-Seq_ESCs_Mouse0.99189477
116SMAD4_21741376_ChIP-Seq_EPCs_Human0.98757554
117E2F1_18555785_Chip-Seq_ESCs_Mouse0.97603980
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.96978530
119TP53_16413492_ChIP-PET_HCT116_Human0.96620759
120CDX2_19796622_ChIP-Seq_MESCs_Mouse0.95864636
121JUN_21703547_ChIP-Seq_K562_Human0.95187219
122CMYC_18555785_Chip-Seq_ESCs_Mouse0.94173570
123NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93483237
124OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.92526266

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.35889494
2MP0003880_abnormal_central_pattern4.29449567
3MP0003635_abnormal_synaptic_transmissio3.20056851
4MP0002735_abnormal_chemical_nociception3.06851981
5MP0009745_abnormal_behavioral_response2.84766536
6MP0001968_abnormal_touch/_nociception2.82185976
7MP0002736_abnormal_nociception_after2.72109400
8MP0005423_abnormal_somatic_nervous2.70584985
9MP0002063_abnormal_learning/memory/cond2.68131593
10MP0002064_seizures2.61507025
11MP0002572_abnormal_emotion/affect_behav2.49498960
12MP0001440_abnormal_grooming_behavior2.36689237
13MP0002272_abnormal_nervous_system2.28187520
14MP0009046_muscle_twitch2.25436818
15MP0004270_analgesia2.17909979
16MP0000778_abnormal_nervous_system2.16611011
17MP0002102_abnormal_ear_morphology2.00616914
18MP0002734_abnormal_mechanical_nocicepti1.96177061
19MP0002067_abnormal_sensory_capabilities1.95086055
20MP0003787_abnormal_imprinting1.86587693
21MP0001501_abnormal_sleep_pattern1.85584560
22MP0005551_abnormal_eye_electrophysiolog1.82373042
23MP0001486_abnormal_startle_reflex1.81306893
24MP0001529_abnormal_vocalization1.80983752
25MP0003122_maternal_imprinting1.80128315
26MP0002184_abnormal_innervation1.77602957
27MP0002638_abnormal_pupillary_reflex1.76964156
28MP0005171_absent_coat_pigmentation1.73123976
29MP0008877_abnormal_DNA_methylation1.71223623
30MP0001502_abnormal_circadian_rhythm1.68060734
31MP0002822_catalepsy1.66590824
32MP0002557_abnormal_social/conspecific_i1.65046521
33MP0004145_abnormal_muscle_electrophysio1.63842252
34MP0001905_abnormal_dopamine_level1.62910293
35MP0008569_lethality_at_weaning1.60284108
36MP0000955_abnormal_spinal_cord1.58639597
37MP0004142_abnormal_muscle_tone1.58568777
38MP0001188_hyperpigmentation1.54517744
39MP0002882_abnormal_neuron_morphology1.52542956
40MP0001970_abnormal_pain_threshold1.49207282
41MP0006276_abnormal_autonomic_nervous1.47818622
42MP0004858_abnormal_nervous_system1.47795737
43MP0005646_abnormal_pituitary_gland1.46667941
44MP0002653_abnormal_ependyma_morphology1.45520163
45MP0006072_abnormal_retinal_apoptosis1.43665803
46MP0002733_abnormal_thermal_nociception1.41509484
47MP0004924_abnormal_behavior1.39969835
48MP0005386_behavior/neurological_phenoty1.39969835
49MP0006292_abnormal_olfactory_placode1.37648365
50MP0005253_abnormal_eye_physiology1.36524809
51MP0001984_abnormal_olfaction1.34862074
52MP0003121_genomic_imprinting1.33675931
53MP0003172_abnormal_lysosome_physiology1.30322319
54MP0000631_abnormal_neuroendocrine_gland1.29870557
55MP0003136_yellow_coat_color1.28895894
56MP0003646_muscle_fatigue1.27333373
57MP0004742_abnormal_vestibular_system1.18686611
58MP0008789_abnormal_olfactory_epithelium1.18001988
59MP0002066_abnormal_motor_capabilities/c1.17872195
60MP0004811_abnormal_neuron_physiology1.17791011
61MP0002152_abnormal_brain_morphology1.15624138
62MP0004885_abnormal_endolymph1.14580894
63MP0001986_abnormal_taste_sensitivity1.14279589
64MP0005645_abnormal_hypothalamus_physiol1.12645383
65MP0009780_abnormal_chondrocyte_physiolo1.12107773
66MP0004133_heterotaxia1.12026272
67MP0002229_neurodegeneration1.11242712
68MP0005394_taste/olfaction_phenotype1.09580466
69MP0005499_abnormal_olfactory_system1.09580466
70MP0002752_abnormal_somatic_nervous1.07376421
71MP0004043_abnormal_pH_regulation1.06897596
72MP0002837_dystrophic_cardiac_calcinosis1.06101234
73MP0000049_abnormal_middle_ear1.04980572
74MP0003123_paternal_imprinting1.04095023
75MP0003890_abnormal_embryonic-extraembry1.03353454
76MP0001963_abnormal_hearing_physiology1.01578231
77MP0002234_abnormal_pharynx_morphology0.99742889
78MP0001485_abnormal_pinna_reflex0.99530938
79MP0004147_increased_porphyrin_level0.98319137
80MP0000751_myopathy0.97402216
81MP0000462_abnormal_digestive_system0.97094753
82MP0003879_abnormal_hair_cell0.96541774
83MP0005409_darkened_coat_color0.92622333
84MP0003861_abnormal_nervous_system0.92462996
85MP0005187_abnormal_penis_morphology0.92207477
86MP0003119_abnormal_digestive_system0.91959907
87MP0002090_abnormal_vision0.91057527
88MP0005195_abnormal_posterior_eye0.90877544
89MP0000569_abnormal_digit_pigmentation0.90387182
90MP0004085_abnormal_heartbeat0.90321298
91MP0010386_abnormal_urinary_bladder0.90229222
92MP0004233_abnormal_muscle_weight0.89941794
93MP0003137_abnormal_impulse_conducting0.89749443
94MP0003634_abnormal_glial_cell0.89696851
95MP0001299_abnormal_eye_distance/0.89357405
96MP0002751_abnormal_autonomic_nervous0.83242497
97MP0002069_abnormal_eating/drinking_beha0.82596672
98MP0002249_abnormal_larynx_morphology0.82158008
99MP0002938_white_spotting0.81534971
100MP0005623_abnormal_meninges_morphology0.80502885
101MP0002876_abnormal_thyroid_physiology0.78572194
102MP0008961_abnormal_basal_metabolism0.78213768
103MP0000749_muscle_degeneration0.77957516
104MP0003633_abnormal_nervous_system0.77745513
105MP0000920_abnormal_myelination0.77535185
106MP0008872_abnormal_physiological_respon0.76182069
107MP0003937_abnormal_limbs/digits/tail_de0.75648190
108MP0004215_abnormal_myocardial_fiber0.75634107
109MP0000516_abnormal_urinary_system0.75549662
110MP0005367_renal/urinary_system_phenotyp0.75549662
111MP0002909_abnormal_adrenal_gland0.75232040
112MP0005257_abnormal_intraocular_pressure0.75140431
113MP0002233_abnormal_nose_morphology0.75133466
114MP0003632_abnormal_nervous_system0.74990645
115MP0003698_abnormal_male_reproductive0.73458193
116MP0003011_delayed_dark_adaptation0.73140728
117MP0003329_amyloid_beta_deposits0.72557181
118MP0000026_abnormal_inner_ear0.72064751
119MP0005620_abnormal_muscle_contractility0.71323611
120MP0000015_abnormal_ear_pigmentation0.65193627
121MP0001177_atelectasis0.64122760
122MP0003690_abnormal_glial_cell0.63874111
123MP0003183_abnormal_peptide_metabolism0.62279841
124MP0003631_nervous_system_phenotype0.61445482
125MP0002082_postnatal_lethality0.59148439
126MP0010770_preweaning_lethality0.59148439

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.27284402
2Myokymia (HP:0002411)4.74433258
3Decreased circulating renin level (HP:0003351)3.87154577
4Epileptic encephalopathy (HP:0200134)3.79005436
5Increased circulating renin level (HP:0000848)3.58384431
6Atonic seizures (HP:0010819)3.39641627
7Febrile seizures (HP:0002373)3.28842819
8Focal seizures (HP:0007359)3.23422232
9Progressive cerebellar ataxia (HP:0002073)3.19309555
10Hyperactive renin-angiotensin system (HP:0000841)2.92944108
11Broad-based gait (HP:0002136)2.92442005
12Abnormality of the labia minora (HP:0012880)2.91015288
13Abnormality of DNA repair (HP:0003254)2.86655030
14Pancreatic cysts (HP:0001737)2.77564348
15True hermaphroditism (HP:0010459)2.74946282
16Dysdiadochokinesis (HP:0002075)2.73519288
17Limb dystonia (HP:0002451)2.73234587
18Lissencephaly (HP:0001339)2.72846328
19Abnormality of the lower motor neuron (HP:0002366)2.72432120
20Pancreatic fibrosis (HP:0100732)2.66993616
21Visual hallucinations (HP:0002367)2.64818076
22Oligodactyly (hands) (HP:0001180)2.64031381
23Absent speech (HP:0001344)2.59366015
24Amblyopia (HP:0000646)2.59105549
25Gaze-evoked nystagmus (HP:0000640)2.57523820
26Dysmetria (HP:0001310)2.53293416
27Drooling (HP:0002307)2.50009672
28Excessive salivation (HP:0003781)2.50009672
29Abnormality of midbrain morphology (HP:0002418)2.47713923
30Molar tooth sign on MRI (HP:0002419)2.47713923
31Type II lissencephaly (HP:0007260)2.42252343
32Dialeptic seizures (HP:0011146)2.40857328
33Congenital malformation of the right heart (HP:0011723)2.40084575
34Double outlet right ventricle (HP:0001719)2.40084575
35Congenital stationary night blindness (HP:0007642)2.38141033
36Hyperaldosteronism (HP:0000859)2.32263716
37Hyperventilation (HP:0002883)2.32139998
38Absence seizures (HP:0002121)2.30592417
39Gait imbalance (HP:0002141)2.30444124
40Spastic gait (HP:0002064)2.26112767
41Septo-optic dysplasia (HP:0100842)2.24108076
42Retinal dysplasia (HP:0007973)2.21213226
43Fetal akinesia sequence (HP:0001989)2.19353752
44Methylmalonic acidemia (HP:0002912)2.16316963
45Epileptiform EEG discharges (HP:0011182)2.16165664
46Deep palmar crease (HP:0006191)2.15676249
47Bony spicule pigmentary retinopathy (HP:0007737)2.15147982
48Scanning speech (HP:0002168)2.14998888
49Aplasia/Hypoplasia of the brainstem (HP:0007362)2.13692598
50Hypoplasia of the brainstem (HP:0002365)2.13692598
51Calf muscle hypertrophy (HP:0008981)2.12773909
52Abnormality of the renal medulla (HP:0100957)2.12606921
53Medial flaring of the eyebrow (HP:0010747)2.12280988
54Abnormality of renin-angiotensin system (HP:0000847)2.12240855
55Inability to walk (HP:0002540)2.11832130
56Increased corneal curvature (HP:0100692)2.11247932
57Keratoconus (HP:0000563)2.11247932
58Supranuclear gaze palsy (HP:0000605)2.09083622
59Generalized tonic-clonic seizures (HP:0002069)2.08375443
60Anomalous pulmonary venous return (HP:0010772)2.06665922
61Specific learning disability (HP:0001328)2.05634542
62Abnormality of the parathyroid morphology (HP:0011766)2.05384526
63Type 2 muscle fiber atrophy (HP:0003554)2.02747089
64Muscle hypertrophy of the lower extremities (HP:0008968)2.02539640
65Hyperkalemia (HP:0002153)2.01783909
66EEG with generalized epileptiform discharges (HP:0011198)2.00239442
67Abnormal eating behavior (HP:0100738)2.00071490
68Abnormality of chromosome segregation (HP:0002916)1.97910803
69Severe visual impairment (HP:0001141)1.97510696
70Central scotoma (HP:0000603)1.97408193
71Genital tract atresia (HP:0001827)1.97078722
72Stereotypic behavior (HP:0000733)1.97030210
73Protruding tongue (HP:0010808)1.96060822
74Sclerocornea (HP:0000647)1.95989766
75Genetic anticipation (HP:0003743)1.95951948
76Truncus arteriosus (HP:0001660)1.94131270
77Partial agenesis of the corpus callosum (HP:0001338)1.92888128
78Abnormality of calcium-phosphate metabolism (HP:0100530)1.91177922
79Truncal ataxia (HP:0002078)1.90559418
80Hemiparesis (HP:0001269)1.89872956
81Postaxial hand polydactyly (HP:0001162)1.89565492
82Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.88963256
83Ankle clonus (HP:0011448)1.88272063
84Intention tremor (HP:0002080)1.88091030
85Vaginal atresia (HP:0000148)1.87977534
86Oligodactyly (HP:0012165)1.87907787
87Congenital primary aphakia (HP:0007707)1.86318935
88Atelectasis (HP:0100750)1.85867857
89Hypoventilation (HP:0002791)1.85814283
90Widely spaced teeth (HP:0000687)1.85651244
91Cutaneous finger syndactyly (HP:0010554)1.85093131
92Nephronophthisis (HP:0000090)1.81931561
93Anophthalmia (HP:0000528)1.79702466
94Action tremor (HP:0002345)1.79150973
95Renal hypoplasia (HP:0000089)1.78022195
96Polyphagia (HP:0002591)1.77908434
97Aplasia/Hypoplasia of the tongue (HP:0010295)1.76267924
98Blue irides (HP:0000635)1.75792936
99Pachygyria (HP:0001302)1.75572112
100Abnormal rod and cone electroretinograms (HP:0008323)1.75525546
101Intestinal atresia (HP:0011100)1.75459036
102Cystic liver disease (HP:0006706)1.75413177
103Aqueductal stenosis (HP:0002410)1.75292080
104Abnormality of the corticospinal tract (HP:0002492)1.75154473
105Absent septum pellucidum (HP:0001331)1.74207509
106Anencephaly (HP:0002323)1.73641442
107Anterior segment dysgenesis (HP:0007700)1.73378483
108Supernumerary spleens (HP:0009799)1.73272259
109Poor coordination (HP:0002370)1.72851689
110Esotropia (HP:0000565)1.72265036
111Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.72203987
112Abnormality of the renal cortex (HP:0011035)1.71199716
113Rimmed vacuoles (HP:0003805)1.70874462
114Abnormality of macular pigmentation (HP:0008002)1.70525588
115Exotropia (HP:0000577)1.70246907
116Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.70133985
117Failure to thrive in infancy (HP:0001531)1.70132217
118Postaxial foot polydactyly (HP:0001830)1.70098622
119Open mouth (HP:0000194)1.69986823
120Abnormal ciliary motility (HP:0012262)1.69429443
121Nephrogenic diabetes insipidus (HP:0009806)1.69396661
122Abnormal hair whorl (HP:0010721)1.68931309
123Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.68794574
124Hypsarrhythmia (HP:0002521)1.68748344
125Poor suck (HP:0002033)1.68702181
126Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.67625376
127Degeneration of the lateral corticospinal tracts (HP:0002314)1.67625376
128Abnormality of the pulmonary veins (HP:0011718)1.66901564
129Agitation (HP:0000713)1.66744496
130Poor eye contact (HP:0000817)1.66655500
131Steppage gait (HP:0003376)1.66646676
132Pheochromocytoma (HP:0002666)1.66229515
133Entropion (HP:0000621)1.64995403
134Methylmalonic aciduria (HP:0012120)1.64812675
135Neurofibrillary tangles (HP:0002185)1.63015565
136Progressive inability to walk (HP:0002505)1.62741809
137Gastroesophageal reflux (HP:0002020)1.62566009
138Prolonged QT interval (HP:0001657)1.61667251
139Optic nerve hypoplasia (HP:0000609)1.61655573
140Neoplasm of the adrenal cortex (HP:0100641)1.61547448
141Diplopia (HP:0000651)1.60819754
142Abnormality of binocular vision (HP:0011514)1.60819754
143Impaired vibration sensation in the lower limbs (HP:0002166)1.60775586
144Lower limb muscle weakness (HP:0007340)1.60773261
145Nemaline bodies (HP:0003798)1.59939090
146Cerebellar dysplasia (HP:0007033)1.59536532
147Narrow forehead (HP:0000341)1.59506706
148Abolished electroretinogram (ERG) (HP:0000550)1.59357149
149Split foot (HP:0001839)1.59062811
150Broad foot (HP:0001769)1.58865066
151Left ventricular hypertrophy (HP:0001712)1.58530793
152Aplasia/Hypoplasia of the tibia (HP:0005772)1.58274384
153Exercise-induced muscle cramps (HP:0003710)1.57536945
154Hepatoblastoma (HP:0002884)1.57439793
155Muscle fiber atrophy (HP:0100295)1.55161175

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.69248860
2TNIK3.43290098
3EPHA43.33341653
4MARK13.13338337
5FES3.10072082
6MAP3K93.01065342
7CASK2.88236346
8FRK2.78978453
9TYRO32.63713807
10PRPF4B2.57395385
11MAPK132.34100988
12MAP4K22.30859055
13NTRK22.21693513
14MAP3K42.09502236
15WNK32.08174724
16KSR11.85222385
17MARK21.80303273
18MAP2K71.73838839
19BRD41.66599707
20MINK11.65387234
21BMPR1B1.58651916
22KSR21.52457236
23AKT31.48665102
24UHMK11.43252206
25PAK61.40257886
26SIK31.33841998
27BRAF1.33514869
28SGK4941.32508192
29SGK2231.32508192
30ICK1.28115685
31GRK11.27889203
32SIK21.24856835
33INSRR1.17915552
34SGK21.15004679
35ARAF1.14352107
36CAMK2A1.13604283
37ADRBK21.11988950
38MKNK21.10591459
39CSNK1G11.10098514
40PLK21.08168210
41PNCK1.08150103
42PHKG21.07669616
43PHKG11.07669616
44CCNB11.04472058
45CDK51.03812309
46CAMK2B1.02488085
47MUSK1.01222177
48CDC42BPA1.00936708
49CSNK1G30.99071911
50DYRK1A0.99041346
51CDK30.97312452
52MAP3K130.96910683
53OXSR10.96361242
54TRIM280.93523062
55LIMK10.93025173
56FGFR20.92564320
57PKN10.92098365
58NUAK10.91185951
59STK380.87898942
60CSNK1G20.87843187
61PRKCG0.87316287
62PAK30.83781239
63CAMK10.83716252
64CDK180.81979426
65CSNK1A1L0.81595308
66STK390.81382730
67TAOK30.81278444
68CAMK2D0.80796610
69DYRK20.80325344
70PRKD30.80204771
71CDK190.79656903
72CDK150.78775349
73WNK40.77333512
74NEK60.75467947
75VRK10.75056284
76DMPK0.74615758
77PRKD20.73730591
78ERBB30.73539382
79CDK140.73192474
80MAPK150.71961786
81NME10.69968022
82CDK11A0.68666553
83SGK10.67486306
84BCR0.64188280
85SGK30.62461324
86STK38L0.61181796
87ROCK20.59620544
88EPHB10.58433154
89ROCK10.58092526
90MAPKAPK50.56875601
91PINK10.56779730
92PRKCZ0.56120890
93MAP2K40.55831148
94RAF10.55065714
95MAP3K20.54561391
96NTRK10.54442435
97CAMK40.53399221
98PRKCE0.52021855
99ZAK0.51120760
100YES10.50655223
101BCKDK0.50217118
102MKNK10.49349114
103PLK30.47569930
104PDGFRB0.46830547
105WNK10.46050086
106RPS6KB10.44887484
107EPHB20.44553755
108CSNK1D0.44268212
109ADRBK10.44249930
110CAMK1G0.43093897
111CAMKK20.42987414
112PRKG10.42537384
113DAPK20.42306944
114IRAK10.42212387
115CHEK20.41654374
116LATS20.39985128
117PRKCH0.39780677
118CAMK2G0.39678332
119CSNK1A10.39131166
120DYRK30.39043100
121ERBB40.38353588
122RPS6KA30.38066527
123RET0.37968942
124IRAK20.37092896
125FYN0.36530115
126STK110.36436052
127EPHA30.35215574
128GSK3B0.34935434
129OBSCN0.34803341
130PRKACA0.34724563
131CSNK1E0.34062236
132MAP3K60.33517689
133CAMKK10.32904627
134PRKACB0.32900359
135PRKDC0.31072166

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.98197921
2Glutamatergic synapse_Homo sapiens_hsa047243.00292116
3Circadian entrainment_Homo sapiens_hsa047132.98473439
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.96036445
5Synaptic vesicle cycle_Homo sapiens_hsa047212.79319774
6GABAergic synapse_Homo sapiens_hsa047272.57430796
7Long-term potentiation_Homo sapiens_hsa047202.53169586
8Morphine addiction_Homo sapiens_hsa050322.33537598
9Amphetamine addiction_Homo sapiens_hsa050312.23748934
10Long-term depression_Homo sapiens_hsa047302.10164285
11Dopaminergic synapse_Homo sapiens_hsa047282.09589957
12Cholinergic synapse_Homo sapiens_hsa047252.07912063
13Serotonergic synapse_Homo sapiens_hsa047262.05199907
14Axon guidance_Homo sapiens_hsa043601.95236404
15Insulin secretion_Homo sapiens_hsa049111.88108106
16Olfactory transduction_Homo sapiens_hsa047401.79937864
17Phototransduction_Homo sapiens_hsa047441.78703877
18Taste transduction_Homo sapiens_hsa047421.78346477
19Circadian rhythm_Homo sapiens_hsa047101.76184717
20Cocaine addiction_Homo sapiens_hsa050301.69979110
21Butanoate metabolism_Homo sapiens_hsa006501.68560147
22Salivary secretion_Homo sapiens_hsa049701.66223170
23Oxytocin signaling pathway_Homo sapiens_hsa049211.58511250
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.55288626
25Collecting duct acid secretion_Homo sapiens_hsa049661.49885629
26Nitrogen metabolism_Homo sapiens_hsa009101.42663012
27Parkinsons disease_Homo sapiens_hsa050121.41790773
28Calcium signaling pathway_Homo sapiens_hsa040201.40528528
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.35293521
30Vibrio cholerae infection_Homo sapiens_hsa051101.34946145
31Renin secretion_Homo sapiens_hsa049241.32680780
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31910856
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.31624107
34Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.30101504
35Type II diabetes mellitus_Homo sapiens_hsa049301.29518963
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28528337
37Cardiac muscle contraction_Homo sapiens_hsa042601.26235670
38cAMP signaling pathway_Homo sapiens_hsa040241.26033264
39Propanoate metabolism_Homo sapiens_hsa006401.23749022
40GnRH signaling pathway_Homo sapiens_hsa049121.22993339
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.13721779
42Basal transcription factors_Homo sapiens_hsa030221.11527893
43Gastric acid secretion_Homo sapiens_hsa049711.11182187
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11154651
45Vascular smooth muscle contraction_Homo sapiens_hsa042701.10563390
46ErbB signaling pathway_Homo sapiens_hsa040121.10068924
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09488795
48Gap junction_Homo sapiens_hsa045401.06810033
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06195748
50Estrogen signaling pathway_Homo sapiens_hsa049151.04017305
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.02445818
52Ether lipid metabolism_Homo sapiens_hsa005651.01467738
53Choline metabolism in cancer_Homo sapiens_hsa052311.00544877
54Dilated cardiomyopathy_Homo sapiens_hsa054140.95217781
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94017524
56Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93577665
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89529889
58Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89265007
59Steroid biosynthesis_Homo sapiens_hsa001000.87532179
60Ovarian steroidogenesis_Homo sapiens_hsa049130.86273753
61Regulation of autophagy_Homo sapiens_hsa041400.84652061
62Fanconi anemia pathway_Homo sapiens_hsa034600.83725328
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.81814563
64RNA degradation_Homo sapiens_hsa030180.80265189
65Linoleic acid metabolism_Homo sapiens_hsa005910.79154778
66Oocyte meiosis_Homo sapiens_hsa041140.77615714
67Renal cell carcinoma_Homo sapiens_hsa052110.77602344
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75679419
69Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.72930056
70alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.72125921
71Glioma_Homo sapiens_hsa052140.72082501
72Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71198292
73Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69255708
74Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.67748048
75Pancreatic secretion_Homo sapiens_hsa049720.67473547
76Melanogenesis_Homo sapiens_hsa049160.66846984
77Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66465082
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.64773113
79Caffeine metabolism_Homo sapiens_hsa002320.64664943
80Wnt signaling pathway_Homo sapiens_hsa043100.64398064
81Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62197053
82Hippo signaling pathway_Homo sapiens_hsa043900.62001063
83Tryptophan metabolism_Homo sapiens_hsa003800.61505608
84Basal cell carcinoma_Homo sapiens_hsa052170.60561366
85beta-Alanine metabolism_Homo sapiens_hsa004100.60074306
86Oxidative phosphorylation_Homo sapiens_hsa001900.59840892
87Sphingolipid metabolism_Homo sapiens_hsa006000.58203270
88MAPK signaling pathway_Homo sapiens_hsa040100.57045593
89Prion diseases_Homo sapiens_hsa050200.57038849
90Endometrial cancer_Homo sapiens_hsa052130.56445443
91Alzheimers disease_Homo sapiens_hsa050100.56402987
92Ras signaling pathway_Homo sapiens_hsa040140.55901967
93Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55374352
94Thyroid hormone synthesis_Homo sapiens_hsa049180.52457745
95Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51828839
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51529647
97Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50071020
98Alcoholism_Homo sapiens_hsa050340.48736856
99Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47693908
100Colorectal cancer_Homo sapiens_hsa052100.47522767
101Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.47440255
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45806776
103Protein export_Homo sapiens_hsa030600.43992277
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43507972
105ABC transporters_Homo sapiens_hsa020100.43093903
106Peroxisome_Homo sapiens_hsa041460.42745003
107Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42057846
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41701133
109Arginine and proline metabolism_Homo sapiens_hsa003300.41661668
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41500134
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.41346439
112RNA polymerase_Homo sapiens_hsa030200.40425888
113Hedgehog signaling pathway_Homo sapiens_hsa043400.40116828
114Glucagon signaling pathway_Homo sapiens_hsa049220.39998444
115Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.39913374
116Dorso-ventral axis formation_Homo sapiens_hsa043200.38957551
117Fatty acid metabolism_Homo sapiens_hsa012120.38171009
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37591542
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37300138
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.36467618
121Lysine degradation_Homo sapiens_hsa003100.35891933
122TGF-beta signaling pathway_Homo sapiens_hsa043500.35643927
123mTOR signaling pathway_Homo sapiens_hsa041500.35440557
124Huntingtons disease_Homo sapiens_hsa050160.35242858
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34156964
126Glycerophospholipid metabolism_Homo sapiens_hsa005640.34104076
127Inositol phosphate metabolism_Homo sapiens_hsa005620.33747284
128mRNA surveillance pathway_Homo sapiens_hsa030150.30347384
129VEGF signaling pathway_Homo sapiens_hsa043700.30052385
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.29179291
131Endocytosis_Homo sapiens_hsa041440.28167942

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