TMEM11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.56590210
2chaperone-mediated protein transport (GO:0072321)5.48331323
3DNA deamination (GO:0045006)5.41011481
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.91158483
5maturation of SSU-rRNA (GO:0030490)4.85667868
6respiratory electron transport chain (GO:0022904)4.73584451
7ribosomal small subunit biogenesis (GO:0042274)4.66555173
8electron transport chain (GO:0022900)4.63810240
9viral transcription (GO:0019083)4.60783399
10protein complex biogenesis (GO:0070271)4.56890745
11proteasome assembly (GO:0043248)4.56671278
12translational termination (GO:0006415)4.54585335
13formation of translation preinitiation complex (GO:0001731)4.52704273
14ribosomal large subunit biogenesis (GO:0042273)4.42678208
15mitochondrial respiratory chain complex assembly (GO:0033108)4.33099544
16NADH dehydrogenase complex assembly (GO:0010257)4.32576800
17mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.32576800
18mitochondrial respiratory chain complex I assembly (GO:0032981)4.32576800
19purine nucleobase biosynthetic process (GO:0009113)4.21400774
20ribonucleoprotein complex biogenesis (GO:0022613)4.21135068
21nucleobase biosynthetic process (GO:0046112)4.20988475
22translational elongation (GO:0006414)4.20017700
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.05486330
24ribosome biogenesis (GO:0042254)4.05419483
25rRNA modification (GO:0000154)4.05099931
26protein neddylation (GO:0045116)4.04514487
27protein targeting to mitochondrion (GO:0006626)4.02964024
28DNA strand elongation involved in DNA replication (GO:0006271)4.01048909
29protein targeting to ER (GO:0045047)4.01003797
30translational initiation (GO:0006413)4.00712170
31cotranslational protein targeting to membrane (GO:0006613)3.94437042
32negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.94097949
33telomere maintenance via semi-conservative replication (GO:0032201)3.92402712
34termination of RNA polymerase III transcription (GO:0006386)3.88138524
35transcription elongation from RNA polymerase III promoter (GO:0006385)3.88138524
36DNA strand elongation (GO:0022616)3.85543067
37rRNA processing (GO:0006364)3.80161641
38protein localization to endoplasmic reticulum (GO:0070972)3.79613904
39ribosome assembly (GO:0042255)3.77836453
40establishment of protein localization to endoplasmic reticulum (GO:0072599)3.77221166
41positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.76647558
42DNA damage response, detection of DNA damage (GO:0042769)3.74492418
43establishment of protein localization to mitochondrion (GO:0072655)3.74246810
44regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.74106510
45translation (GO:0006412)3.72982929
46DNA replication initiation (GO:0006270)3.72019544
47protein localization to mitochondrion (GO:0070585)3.71855547
48anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.71451113
49viral life cycle (GO:0019058)3.70954730
50DNA replication checkpoint (GO:0000076)3.68972790
51pseudouridine synthesis (GO:0001522)3.68605020
52rRNA metabolic process (GO:0016072)3.66771817
53nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65539103
54L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.64944996
55spliceosomal snRNP assembly (GO:0000387)3.63286215
56pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.61266970
57negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.60796087
58negative regulation of ligase activity (GO:0051352)3.60796087
59protein deneddylation (GO:0000338)3.57121154
60DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.56403964
61respiratory chain complex IV assembly (GO:0008535)3.56213191
62cellular component biogenesis (GO:0044085)3.55241521
63oxidative phosphorylation (GO:0006119)3.54404782
64nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.53360710
65cellular protein complex disassembly (GO:0043624)3.52251255
66chromatin remodeling at centromere (GO:0031055)3.51249555
67cullin deneddylation (GO:0010388)3.51151338
68signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.51089609
69intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.51089609
70mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.50718933
71signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.50209869
72signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.50209869
73signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.50209869
74CENP-A containing nucleosome assembly (GO:0034080)3.48766619
75deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.48423969
76exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.48391050
77RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.45665113
78tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.45665113
79telomere maintenance via recombination (GO:0000722)3.45005961
80signal transduction involved in DNA integrity checkpoint (GO:0072401)3.42991485
81signal transduction involved in DNA damage checkpoint (GO:0072422)3.42991485
82cytochrome complex assembly (GO:0017004)3.40634923
83signal transduction involved in cell cycle checkpoint (GO:0072395)3.36943354
84regulation of cellular amino acid metabolic process (GO:0006521)3.36263534
85IMP biosynthetic process (GO:0006188)3.35387890
86inner mitochondrial membrane organization (GO:0007007)3.35323107
87positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.34928173
88antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.29044736
89regulation of mitochondrial translation (GO:0070129)3.28834752
907-methylguanosine mRNA capping (GO:0006370)3.24957882
91regulation of ligase activity (GO:0051340)3.24564413
92ubiquinone biosynthetic process (GO:0006744)3.23340200
93rRNA methylation (GO:0031167)3.22375466
94mitotic metaphase plate congression (GO:0007080)3.21728352
95positive regulation of ligase activity (GO:0051351)3.20158458
96energy coupled proton transport, down electrochemical gradient (GO:0015985)3.19813899
97ATP synthesis coupled proton transport (GO:0015986)3.19813899
98pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.19697235
99DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.19628755
100mitotic recombination (GO:0006312)3.19028976
101base-excision repair, AP site formation (GO:0006285)3.18137562
102G1/S transition of mitotic cell cycle (GO:0000082)3.18041399
103cell cycle G1/S phase transition (GO:0044843)3.18041399
104mitochondrial transport (GO:0006839)3.17596450
105RNA capping (GO:0036260)3.16708504
1067-methylguanosine RNA capping (GO:0009452)3.16708504
107protein-cofactor linkage (GO:0018065)3.16495016
108regulation of cellular amine metabolic process (GO:0033238)3.14055166
109peptidyl-histidine modification (GO:0018202)3.13061318
110establishment of integrated proviral latency (GO:0075713)3.12715277
111telomere maintenance via telomere lengthening (GO:0010833)3.11848441
112L-methionine salvage (GO:0071267)3.10614369
113L-methionine biosynthetic process (GO:0071265)3.10614369
114amino acid salvage (GO:0043102)3.10614369
115protein complex disassembly (GO:0043241)3.09563081
116antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.09290666
117folic acid-containing compound biosynthetic process (GO:0009396)3.07492079
118transcription-coupled nucleotide-excision repair (GO:0006283)3.06279720
119establishment of protein localization to mitochondrial membrane (GO:0090151)3.05805395
120ubiquinone metabolic process (GO:0006743)3.04950504
121sequestering of actin monomers (GO:0042989)3.04196097
122protein K6-linked ubiquitination (GO:0085020)3.03773533
123metallo-sulfur cluster assembly (GO:0031163)3.02735652
124iron-sulfur cluster assembly (GO:0016226)3.02735652
125kinetochore assembly (GO:0051382)3.01955304
126ATP biosynthetic process (GO:0006754)3.01778031
127purine nucleoside triphosphate biosynthetic process (GO:0009145)3.01339444
128regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.01094717
129DNA replication-independent nucleosome assembly (GO:0006336)3.00668009
130DNA replication-independent nucleosome organization (GO:0034724)3.00668009
131regulation of ubiquitin-protein transferase activity (GO:0051438)2.99033268
132macromolecular complex disassembly (GO:0032984)2.98369733
133IMP metabolic process (GO:0046040)2.97648508
134purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.97356218
135negative regulation of protein ubiquitination (GO:0031397)2.97126488
136transcription from RNA polymerase I promoter (GO:0006360)2.96022201
137positive regulation of cell cycle arrest (GO:0071158)2.95354531
138mitotic nuclear envelope disassembly (GO:0007077)2.94668071
139hydrogen ion transmembrane transport (GO:1902600)2.94342621
140mannosylation (GO:0097502)2.93959892
141protein localization to kinetochore (GO:0034501)2.93526714
142nuclear-transcribed mRNA catabolic process (GO:0000956)2.92489595
143establishment of viral latency (GO:0019043)2.88242007
144intracellular protein transmembrane import (GO:0044743)2.85549273
145GTP biosynthetic process (GO:0006183)2.83353809
146DNA catabolic process, exonucleolytic (GO:0000738)2.83094772
147pyrimidine nucleotide catabolic process (GO:0006244)2.81005694

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.81982900
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.50640596
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.02507231
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.73129677
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.51773773
6* EST1_17652178_ChIP-ChIP_JURKAT_Human3.47939997
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.46506836
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.23503298
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.14892444
10* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.01628092
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.97784214
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91687191
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.75955644
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.72388963
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.60983769
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.48270133
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.47522468
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.47047583
19XRN2_22483619_ChIP-Seq_HELA_Human2.43793699
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.42069032
21VDR_23849224_ChIP-Seq_CD4+_Human2.38705809
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35094791
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.34571413
24DCP1A_22483619_ChIP-Seq_HELA_Human2.20703118
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.19324857
26FOXM1_23109430_ChIP-Seq_U2OS_Human2.18016654
27FOXP3_21729870_ChIP-Seq_TREG_Human2.09694543
28GABP_19822575_ChIP-Seq_HepG2_Human2.04141650
29* SRF_21415370_ChIP-Seq_HL-1_Mouse2.03094302
30* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.99498632
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.96761705
32YY1_21170310_ChIP-Seq_MESCs_Mouse1.95265142
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86633102
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.85982826
35TTF2_22483619_ChIP-Seq_HELA_Human1.84305528
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.83516786
37* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.82934739
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73526853
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.73180848
40* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71050946
41TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.70972626
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68576772
43ELK1_19687146_ChIP-ChIP_HELA_Human1.67995953
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.67111741
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65160885
46AR_21909140_ChIP-Seq_LNCAP_Human1.63305737
47* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59574385
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58875846
49ZFX_18555785_ChIP-Seq_MESCs_Mouse1.57385875
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.56650630
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.52234707
52E2F1_21310950_ChIP-Seq_MCF-7_Human1.50215625
53STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47307585
54* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47212222
55CIITA_25753668_ChIP-Seq_RAJI_Human1.45199477
56CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.44212572
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.43122288
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.40192905
59POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.39351864
60ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31501080
61* KDM5A_27292631_Chip-Seq_BREAST_Human1.31053633
62CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.30012762
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29070889
64BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.28091877
65ZNF274_21170338_ChIP-Seq_K562_Hela1.20087838
66MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20008855
67NOTCH1_21737748_ChIP-Seq_TLL_Human1.17770369
68ELK1_22589737_ChIP-Seq_MCF10A_Human1.15843638
69TFEB_21752829_ChIP-Seq_HELA_Human1.11729450
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.11311885
71* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.08799856
72MYC_18940864_ChIP-ChIP_HL60_Human1.07097645
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06777912
74* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.02636483
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02121213
76SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00266059
77MYC_22102868_ChIP-Seq_BL_Human0.99733535
78HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.97957750
79HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97751299
80CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97458114
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97416134
82SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97140020
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.96869904
84* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96633652
85SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96316244
86NANOG_16153702_ChIP-ChIP_HESCs_Human0.96287120
87* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95992305
88OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95538607
89CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94758009
90ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94397269
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94141893
92SOX2_18692474_ChIP-Seq_MEFs_Mouse0.92331241
93SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91790480
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.91347802
95* FOXP1_21924763_ChIP-Seq_HESCs_Human0.89878471
96SOX2_16153702_ChIP-ChIP_HESCs_Human0.89350126
97GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.88254193
98TCF3_18692474_ChIP-Seq_MEFs_Mouse0.87060043
99* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.86829976
100PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.84693876
101SPI1_23547873_ChIP-Seq_NB4_Human0.83563511
102* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.83101272
103TBX5_21415370_ChIP-Seq_HL-1_Mouse0.81797151
104NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.80911801
105PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.80847896
106* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.80415907
107EGR1_19374776_ChIP-ChIP_THP-1_Human0.79797257
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.78482821
109* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75094554
110ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.73444351
111* SOX17_20123909_ChIP-Seq_XEN_Mouse0.73409889
112TP53_22573176_ChIP-Seq_HFKS_Human0.72943692
113CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.72820345
114SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.72566082
115IRF1_19129219_ChIP-ChIP_H3396_Human0.70865717
116POU5F1_16153702_ChIP-ChIP_HESCs_Human0.66692468
117HTT_18923047_ChIP-ChIP_STHdh_Human0.66357195

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.37557064
2MP0004957_abnormal_blastocyst_morpholog4.14243957
3MP0010094_abnormal_chromosome_stability3.59346903
4MP0003111_abnormal_nucleus_morphology3.59291728
5MP0003077_abnormal_cell_cycle3.46850489
6MP0003806_abnormal_nucleotide_metabolis3.29387300
7MP0008058_abnormal_DNA_repair3.07265731
8MP0008007_abnormal_cellular_replicative3.03477292
9MP0006292_abnormal_olfactory_placode2.75767832
10MP0002102_abnormal_ear_morphology2.71505135
11MP0003123_paternal_imprinting2.58112068
12MP0008057_abnormal_DNA_replication2.56066877
13MP0008932_abnormal_embryonic_tissue2.53681905
14MP0001529_abnormal_vocalization2.48974073
15MP0008789_abnormal_olfactory_epithelium2.48617521
16MP0003186_abnormal_redox_activity2.21362542
17MP0002938_white_spotting2.17720055
18MP0004145_abnormal_muscle_electrophysio2.14696174
19MP0002396_abnormal_hematopoietic_system2.10940425
20MP0003786_premature_aging2.06500371
21MP0003136_yellow_coat_color2.02302423
22MP0003718_maternal_effect2.01135997
23MP0001730_embryonic_growth_arrest1.98641320
24MP0006036_abnormal_mitochondrial_physio1.92722847
25MP0003646_muscle_fatigue1.85727354
26MP0000350_abnormal_cell_proliferation1.77756489
27MP0008877_abnormal_DNA_methylation1.76343785
28MP0003315_abnormal_perineum_morphology1.72566280
29MP0005084_abnormal_gallbladder_morpholo1.66739025
30MP0000490_abnormal_crypts_of1.65137380
31MP0005394_taste/olfaction_phenotype1.61683891
32MP0005499_abnormal_olfactory_system1.61683891
33MP0003567_abnormal_fetal_cardiomyocyte1.59816720
34MP0002277_abnormal_respiratory_mucosa1.49808446
35MP0001697_abnormal_embryo_size1.48903487
36MP0003941_abnormal_skin_development1.48537491
37MP0009333_abnormal_splenocyte_physiolog1.48495881
38MP0002132_abnormal_respiratory_system1.46663440
39MP0006035_abnormal_mitochondrial_morpho1.46454483
40MP0010352_gastrointestinal_tract_polyps1.44239188
41MP0005408_hypopigmentation1.42275924
42MP0004147_increased_porphyrin_level1.41883750
43MP0000313_abnormal_cell_death1.41715794
44MP0001545_abnormal_hematopoietic_system1.37605188
45MP0005397_hematopoietic_system_phenotyp1.37605188
46MP0002638_abnormal_pupillary_reflex1.36616797
47MP0004808_abnormal_hematopoietic_stem1.35057729
48MP0002080_prenatal_lethality1.34948438
49MP0002837_dystrophic_cardiac_calcinosis1.34786540
50MP0005380_embryogenesis_phenotype1.33807650
51MP0001672_abnormal_embryogenesis/_devel1.33807650
52MP0003011_delayed_dark_adaptation1.33518464
53MP0004084_abnormal_cardiac_muscle1.32444652
54MP0001905_abnormal_dopamine_level1.31613147
55MP0003984_embryonic_growth_retardation1.29944934
56MP0002019_abnormal_tumor_incidence1.28374693
57MP0008995_early_reproductive_senescence1.27131163
58MP0002088_abnormal_embryonic_growth/wei1.26935619
59MP0002095_abnormal_skin_pigmentation1.26528295
60MP0002736_abnormal_nociception_after1.25466769
61MP0002234_abnormal_pharynx_morphology1.23624377
62MP0005171_absent_coat_pigmentation1.23137827
63MP0001984_abnormal_olfaction1.20463127
64MP0000049_abnormal_middle_ear1.20314107
65MP0000358_abnormal_cell_content/1.13825430
66MP0004142_abnormal_muscle_tone1.12790141
67MP0001293_anophthalmia1.12703226
68MP0005266_abnormal_metabolism1.12453921
69MP0010030_abnormal_orbit_morphology1.12410222
70MP0005075_abnormal_melanosome_morpholog1.08763511
71MP0000750_abnormal_muscle_regeneration1.08103313
72MP0002086_abnormal_extraembryonic_tissu1.08072552
73MP0009379_abnormal_foot_pigmentation1.06603361
74MP0005253_abnormal_eye_physiology1.06449913
75MP0002085_abnormal_embryonic_tissue1.05907039
76MP0006276_abnormal_autonomic_nervous1.04084799
77MP0003763_abnormal_thymus_physiology1.02922652
78MP0006072_abnormal_retinal_apoptosis1.02277512
79MP0001764_abnormal_homeostasis1.01143610
80MP0001853_heart_inflammation0.98989878
81MP0009697_abnormal_copulation0.98725887
82MP0005083_abnormal_biliary_tract0.98719220
83MP0003221_abnormal_cardiomyocyte_apopto0.98183208
84MP0009053_abnormal_anal_canal0.97600713
85MP0003283_abnormal_digestive_organ0.97579904
86MP0005377_hearing/vestibular/ear_phenot0.97106804
87MP0003878_abnormal_ear_physiology0.97106804
88MP0004197_abnormal_fetal_growth/weight/0.93648491
89MP0002160_abnormal_reproductive_system0.93465969
90MP0003137_abnormal_impulse_conducting0.93307894
91MP0002090_abnormal_vision0.91965328
92MP0002210_abnormal_sex_determination0.90755961
93MP0000749_muscle_degeneration0.87488650
94MP0000689_abnormal_spleen_morphology0.86658174
95MP0005330_cardiomyopathy0.86493995
96MP0001929_abnormal_gametogenesis0.86335711
97MP0001145_abnormal_male_reproductive0.86163090
98MP0003195_calcinosis0.86108295
99MP0003566_abnormal_cell_adhesion0.84674921
100MP0002722_abnormal_immune_system0.84466171
101MP0002084_abnormal_developmental_patter0.82765009
102MP0006138_congestive_heart_failure0.82466644
103MP0003119_abnormal_digestive_system0.82066477
104MP0000858_altered_metastatic_potential0.81684004
105MP0004133_heterotaxia0.81443484
106MP0001324_abnormal_eye_pigmentation0.80931289
107MP0002163_abnormal_gland_morphology0.80525849
108MP0000751_myopathy0.80183790
109MP0002233_abnormal_nose_morphology0.79805210
110MP0001119_abnormal_female_reproductive0.78455583
111MP0001188_hyperpigmentation0.78270330
112MP0002398_abnormal_bone_marrow0.77789145
113MP0001542_abnormal_bone_strength0.77672448
114MP0001986_abnormal_taste_sensitivity0.74569997
115MP0002106_abnormal_muscle_physiology0.73980721
116MP0009046_muscle_twitch0.73625686
117MP0000372_irregular_coat_pigmentation0.72965817
118MP0002429_abnormal_blood_cell0.72581729
119MP0002751_abnormal_autonomic_nervous0.72382756
120MP0004215_abnormal_myocardial_fiber0.72377402
121MP0000703_abnormal_thymus_morphology0.71992081
122MP0005384_cellular_phenotype0.71346888
123MP0000653_abnormal_sex_gland0.71326401
124MP0006054_spinal_hemorrhage0.70360063
125MP0001727_abnormal_embryo_implantation0.70347644
126MP0000477_abnormal_intestine_morphology0.69601268
127MP0002111_abnormal_tail_morphology0.67895379
128MP0002269_muscular_atrophy0.67614275
129MP0000631_abnormal_neuroendocrine_gland0.67611229
130MP0005389_reproductive_system_phenotype0.67427384
131MP0008872_abnormal_physiological_respon0.67176910
132MP0002177_abnormal_outer_ear0.66425323
133MP0001968_abnormal_touch/_nociception0.66395107
134MP0000015_abnormal_ear_pigmentation0.65461981
135MP0005332_abnormal_amino_acid0.65288379
136MP0001835_abnormal_antigen_presentation0.64625203
137MP0003828_pulmonary_edema0.63398620
138MP0000343_altered_response_to0.60922206
139MP0003122_maternal_imprinting0.60647144
140MP0005376_homeostasis/metabolism_phenot0.60178246
141MP0005369_muscle_phenotype0.60129310
142MP0003943_abnormal_hepatobiliary_system0.59572641
143MP0005621_abnormal_cell_physiology0.59548822
144MP0005451_abnormal_body_composition0.58833141
145MP0005385_cardiovascular_system_phenoty0.58145708
146MP0001544_abnormal_cardiovascular_syste0.58145708
147MP0010307_abnormal_tumor_latency0.56642220
148MP0002127_abnormal_cardiovascular_syste0.56453570
149MP0004233_abnormal_muscle_weight0.55962161
150MP0000678_abnormal_parathyroid_gland0.55851744
151MP0003121_genomic_imprinting0.54998971
152MP0004782_abnormal_surfactant_physiolog0.54927238
153MP0009672_abnormal_birth_weight0.54880880
154MP0002653_abnormal_ependyma_morphology0.54810419

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.91369797
2Breast hypoplasia (HP:0003187)4.30528758
3Abnormality of cells of the erythroid lineage (HP:0012130)4.28786373
4Reticulocytopenia (HP:0001896)4.11709979
5Abnormal number of erythroid precursors (HP:0012131)4.06997587
6Aplastic anemia (HP:0001915)3.88576911
7Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.69616519
8Microretrognathia (HP:0000308)3.64603963
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.53064372
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.53064372
11Mitochondrial inheritance (HP:0001427)3.48323460
12Acute necrotizing encephalopathy (HP:0006965)3.47347882
13Carpal bone hypoplasia (HP:0001498)3.41605241
14Oral leukoplakia (HP:0002745)3.38639669
15Abnormal mitochondria in muscle tissue (HP:0008316)3.36461679
16Increased CSF lactate (HP:0002490)3.32803085
17Hepatocellular necrosis (HP:0001404)3.26810827
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.25796000
19Hepatic necrosis (HP:0002605)3.24117080
20Increased hepatocellular lipid droplets (HP:0006565)3.18216358
21Increased serum lactate (HP:0002151)3.15321681
22Rough bone trabeculation (HP:0100670)3.14378273
233-Methylglutaconic aciduria (HP:0003535)3.03917516
24Lipid accumulation in hepatocytes (HP:0006561)3.02136450
25Macrocytic anemia (HP:0001972)3.00878757
26Degeneration of anterior horn cells (HP:0002398)2.97443199
27Abnormality of the anterior horn cell (HP:0006802)2.97443199
28Acute encephalopathy (HP:0006846)2.94989362
29Increased intramyocellular lipid droplets (HP:0012240)2.86988576
30Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.86773452
31Abnormal protein N-linked glycosylation (HP:0012347)2.86773452
32Abnormal protein glycosylation (HP:0012346)2.86773452
33Abnormal glycosylation (HP:0012345)2.86773452
34Patellar aplasia (HP:0006443)2.80371379
35Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.79097356
36Abnormality of alanine metabolism (HP:0010916)2.79097356
37Hyperalaninemia (HP:0003348)2.79097356
38Multiple enchondromatosis (HP:0005701)2.77147301
39Cerebral hypomyelination (HP:0006808)2.76178335
40Abnormality of glycolysis (HP:0004366)2.72746583
41Increased serum pyruvate (HP:0003542)2.72746583
42Exercise intolerance (HP:0003546)2.71724927
43Respiratory difficulties (HP:0002880)2.69497793
44Exertional dyspnea (HP:0002875)2.68957070
45Lactic acidosis (HP:0003128)2.68759974
46Pallor (HP:0000980)2.66302913
47Irregular epiphyses (HP:0010582)2.65487109
48Aplasia/Hypoplasia of the patella (HP:0006498)2.65310472
49Progressive muscle weakness (HP:0003323)2.63744199
50Selective tooth agenesis (HP:0001592)2.63330370
51Generalized aminoaciduria (HP:0002909)2.59856798
52Increased muscle lipid content (HP:0009058)2.59316962
53Optic disc pallor (HP:0000543)2.56814133
54Trismus (HP:0000211)2.56521985
55Type I transferrin isoform profile (HP:0003642)2.53324774
56Nemaline bodies (HP:0003798)2.51484308
57Hypoplastic pelvis (HP:0008839)2.47947061
58Progressive macrocephaly (HP:0004481)2.44082675
59Amniotic constriction ring (HP:0009775)2.41429941
60Abnormality of placental membranes (HP:0011409)2.41429941
61Lethargy (HP:0001254)2.37500538
62Renal Fanconi syndrome (HP:0001994)2.37137107
63Reduced antithrombin III activity (HP:0001976)2.36796985
64Abnormality of renal resorption (HP:0011038)2.36365585
65Muscle fiber inclusion bodies (HP:0100299)2.34982855
66Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.32514391
67Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.28542873
68Premature ovarian failure (HP:0008209)2.27984173
69Respiratory failure (HP:0002878)2.27165226
70Colon cancer (HP:0003003)2.24508952
71Methylmalonic aciduria (HP:0012120)2.23112581
72Aplasia/Hypoplasia of the sacrum (HP:0008517)2.22381519
73Pancytopenia (HP:0001876)2.20927377
74Sparse eyelashes (HP:0000653)2.18861063
75Leukodystrophy (HP:0002415)2.18100196
76Secondary amenorrhea (HP:0000869)2.16860900
77Absent thumb (HP:0009777)2.16628665
78Nausea (HP:0002018)2.16337653
79Abnormal trabecular bone morphology (HP:0100671)2.15978317
80Premature graying of hair (HP:0002216)2.15822307
81Methylmalonic acidemia (HP:0002912)2.14686975
8211 pairs of ribs (HP:0000878)2.12023848
83Cerebral edema (HP:0002181)2.11951249
84Breech presentation (HP:0001623)2.09394700
85Chromsome breakage (HP:0040012)2.07416684
86Petechiae (HP:0000967)2.07042844
87Thrombocytosis (HP:0001894)2.05744196
88Exercise-induced muscle cramps (HP:0003710)2.04044451
89Pancreatic cysts (HP:0001737)2.03654879
90Cellular immunodeficiency (HP:0005374)2.01871205
91Microvesicular hepatic steatosis (HP:0001414)2.00580817
92X-linked dominant inheritance (HP:0001423)1.99837642
93Rhabdomyolysis (HP:0003201)1.98875499
94Abnormality of urine glucose concentration (HP:0011016)1.98111561
95Glycosuria (HP:0003076)1.98111561
96Flat capital femoral epiphysis (HP:0003370)1.97754389
97Neoplasm of the pancreas (HP:0002894)1.97666624
98Hypoplasia of the radius (HP:0002984)1.96905590
99CNS demyelination (HP:0007305)1.96694373
100Abnormality of the labia minora (HP:0012880)1.95494064
101Hyperglycinemia (HP:0002154)1.95265947
102Posterior subcapsular cataract (HP:0007787)1.95010759
103Abnormality of the preputium (HP:0100587)1.94966652
104Abnormal lung lobation (HP:0002101)1.93762616
105Abnormality of methionine metabolism (HP:0010901)1.89427067
106Abnormal cartilage morphology (HP:0002763)1.88395096
107Ragged-red muscle fibers (HP:0003200)1.87942366
108Meckel diverticulum (HP:0002245)1.86987953
109Slender long bone (HP:0003100)1.86214654
110Horseshoe kidney (HP:0000085)1.85984559
111Unsteady gait (HP:0002317)1.84208695
112Chromosomal breakage induced by crosslinking agents (HP:0003221)1.83240048
113Poor suck (HP:0002033)1.83130491
114Dicarboxylic aciduria (HP:0003215)1.80479500
115Abnormality of dicarboxylic acid metabolism (HP:0010995)1.80479500
116Cleft eyelid (HP:0000625)1.80365644
117Abnormality of the ileum (HP:0001549)1.80080023
118Emotional lability (HP:0000712)1.77636033
119Absent radius (HP:0003974)1.77299003
120Abnormality of midbrain morphology (HP:0002418)1.76919462
121Molar tooth sign on MRI (HP:0002419)1.76919462
122Muscle fiber atrophy (HP:0100295)1.76699003
123Abnormal number of incisors (HP:0011064)1.76568063
124Areflexia of lower limbs (HP:0002522)1.75723381
125Abnormality of chromosome stability (HP:0003220)1.73979784
126Type 2 muscle fiber atrophy (HP:0003554)1.72861055
127Tongue fasciculations (HP:0001308)1.72176512
128Abnormality of the umbilical cord (HP:0010881)1.71896221
129Bone marrow hypocellularity (HP:0005528)1.71513316
130IgM deficiency (HP:0002850)1.71419254
131Renal cortical cysts (HP:0000803)1.71336413
132Megaloblastic anemia (HP:0001889)1.70831951
133Opisthotonus (HP:0002179)1.70172552
134Pancreatic fibrosis (HP:0100732)1.70093859
135Medial flaring of the eyebrow (HP:0010747)1.67846537
136True hermaphroditism (HP:0010459)1.67344643
137Abnormality of the fovea (HP:0000493)1.66742978
138Progressive microcephaly (HP:0000253)1.65849547
139Aplasia/hypoplasia of the uterus (HP:0008684)1.63850227
140Abnormality of serum amino acid levels (HP:0003112)1.62342709
141Sclerocornea (HP:0000647)1.62310301
142Adrenal hypoplasia (HP:0000835)1.61876881
143Median cleft lip (HP:0000161)1.61415859
144Hypoplasia of the fovea (HP:0007750)1.59079561
145Aplasia/Hypoplasia of the fovea (HP:0008060)1.59079561

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.34236542
2TIE14.28658505
3VRK24.14720094
4WEE13.99477501
5EIF2AK13.56084769
6NME23.48475007
7TSSK62.50142522
8EIF2AK32.33208857
9BCKDK2.30763324
10CDC72.20747111
11TAOK32.15397617
12PIM22.15199777
13PLK42.14444661
14STK162.08452666
15TRIM282.03052002
16NEK12.02605617
17BRSK21.90012089
18SRPK11.86624227
19ACVR1B1.85752984
20CSNK1G31.85534029
21VRK11.71832238
22TTK1.65809625
23KDR1.61721447
24NUAK11.61672321
25PLK11.61260729
26DYRK31.58059283
27ZAK1.55440401
28TESK21.52668427
29TGFBR11.51636583
30CSNK1G11.49253650
31CSNK1A1L1.42947776
32EPHA21.41252837
33CSNK1G21.40154983
34PASK1.38563556
35NEK21.37955679
36TEC1.36664194
37AURKB1.32012146
38BMPR1B1.29359714
39MAP4K21.26464552
40RPS6KA41.26373275
41IRAK31.24993174
42CDK71.24200757
43MAP2K71.23565815
44WNK31.23338116
45NME11.22060751
46CDK81.20008282
47PHKG11.17959187
48PHKG21.17959187
49RPS6KB21.15922987
50MAP3K111.14238959
51BRSK11.13856118
52ATR1.08774623
53MAPKAPK31.07705583
54CCNB11.06627249
55PLK31.05272399
56BRAF1.01724681
57MKNK10.97666133
58ARAF0.97388570
59AURKA0.96029297
60ILK0.93844980
61STK38L0.93451512
62FLT30.92661901
63ADRBK20.91848427
64PINK10.91525940
65MYLK0.90870322
66PAK40.89711712
67BCR0.85151890
68MAP2K30.82657468
69PDK40.81981551
70PDK30.81981551
71PBK0.79106783
72EIF2AK20.77724985
73MAP3K80.76104825
74TLK10.76101808
75CHEK20.75374954
76TESK10.73749424
77PLK20.72219991
78MAP3K120.70510762
79CDK40.68316950
80MUSK0.68028119
81DYRK20.67825636
82CSNK2A10.67588347
83PRKCI0.65758067
84OBSCN0.64500418
85PIK3CG0.64296997
86ERBB30.62119407
87MAP3K30.62112905
88GRK70.60122115
89SIK30.59847955
90EPHB20.59770202
91PIM10.58820717
92CSNK2A20.58647834
93AKT30.58643830
94MKNK20.56685733
95CHEK10.55943341
96STK240.55719798
97GRK10.54491679
98PAK10.54323100
99LMTK20.50532828
100DAPK30.50396947
101ABL20.49820893
102PDK20.48670736
103LRRK20.47534584
104LATS20.44539891
105INSRR0.44464080
106DAPK10.43771659
107ATM0.41864941
108CSNK1A10.41565859
109STK40.41141111
110LIMK10.40958906
111MINK10.39908144
112ERN10.39629563
113GRK50.39394009
114AKT20.38350602
115MAP4K10.37718515
116CDK20.35006603
117MAP3K50.34669718
118MAPK130.34171469
119PRKCG0.33250095
120MAP2K20.32915128
121SCYL20.32060598
122CDK190.31995472
123TAOK20.31980635
124TAF10.30976268
125RAF10.30957828
126PKN10.30312745
127WNK40.30198067
128RPS6KA50.29556530
129STK100.28039795
130MST40.27850611
131ADRBK10.27343599
132ZAP700.27296066
133CAMK2G0.26467490
134CSNK1E0.26357576
135CDK140.24058627

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.42459335
2Proteasome_Homo sapiens_hsa030504.22454289
3DNA replication_Homo sapiens_hsa030304.01984333
4RNA polymerase_Homo sapiens_hsa030203.81289457
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.40813604
6Mismatch repair_Homo sapiens_hsa034303.38917809
7Spliceosome_Homo sapiens_hsa030402.77441774
8Pyrimidine metabolism_Homo sapiens_hsa002402.73583951
9RNA transport_Homo sapiens_hsa030132.59004711
10Base excision repair_Homo sapiens_hsa034102.55492462
11Homologous recombination_Homo sapiens_hsa034402.52759842
12Nucleotide excision repair_Homo sapiens_hsa034202.26558642
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.17803787
14Oxidative phosphorylation_Homo sapiens_hsa001902.16643709
15Parkinsons disease_Homo sapiens_hsa050122.10409215
16One carbon pool by folate_Homo sapiens_hsa006702.06155039
17Cell cycle_Homo sapiens_hsa041101.96299803
18Fatty acid elongation_Homo sapiens_hsa000621.87521556
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.83586703
20Sulfur relay system_Homo sapiens_hsa041221.69424915
21Basal transcription factors_Homo sapiens_hsa030221.68468233
22Huntingtons disease_Homo sapiens_hsa050161.67188847
23RNA degradation_Homo sapiens_hsa030181.62871856
24Protein export_Homo sapiens_hsa030601.52929667
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.49031067
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.48070508
27Fanconi anemia pathway_Homo sapiens_hsa034601.46929910
28Purine metabolism_Homo sapiens_hsa002301.44427051
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.41401359
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.36168078
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.31582553
32Non-homologous end-joining_Homo sapiens_hsa034501.28821342
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.26861894
34Pentose phosphate pathway_Homo sapiens_hsa000301.26231999
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.25926317
36Folate biosynthesis_Homo sapiens_hsa007901.20043669
37p53 signaling pathway_Homo sapiens_hsa041151.17304148
38Fructose and mannose metabolism_Homo sapiens_hsa000511.16343394
39Biosynthesis of amino acids_Homo sapiens_hsa012301.13897532
40Alzheimers disease_Homo sapiens_hsa050101.11945771
41Epstein-Barr virus infection_Homo sapiens_hsa051691.07619518
42Carbon metabolism_Homo sapiens_hsa012001.07618517
43Drug metabolism - other enzymes_Homo sapiens_hsa009831.06238902
44Collecting duct acid secretion_Homo sapiens_hsa049661.01655938
45Steroid biosynthesis_Homo sapiens_hsa001000.94705864
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.94389204
47mRNA surveillance pathway_Homo sapiens_hsa030150.87269812
48Butanoate metabolism_Homo sapiens_hsa006500.84608072
49Vitamin B6 metabolism_Homo sapiens_hsa007500.82674710
50Glutathione metabolism_Homo sapiens_hsa004800.81603965
51Galactose metabolism_Homo sapiens_hsa000520.79739346
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75140347
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72526607
54Legionellosis_Homo sapiens_hsa051340.71172444
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71122834
56Antigen processing and presentation_Homo sapiens_hsa046120.68450662
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66223825
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.65598460
59Herpes simplex infection_Homo sapiens_hsa051680.64392264
60Selenocompound metabolism_Homo sapiens_hsa004500.59266872
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.58617724
62Metabolic pathways_Homo sapiens_hsa011000.57811701
63Cardiac muscle contraction_Homo sapiens_hsa042600.56618351
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.52966031
65Pyruvate metabolism_Homo sapiens_hsa006200.50032490
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48629421
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48591335
68Fatty acid metabolism_Homo sapiens_hsa012120.47778972
69Thyroid cancer_Homo sapiens_hsa052160.47194401
70HIF-1 signaling pathway_Homo sapiens_hsa040660.46970142
71Vibrio cholerae infection_Homo sapiens_hsa051100.43037395
72Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42955124
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.41866709
74Tryptophan metabolism_Homo sapiens_hsa003800.40892062
75Phototransduction_Homo sapiens_hsa047440.40846478
76Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39568882
77Fatty acid degradation_Homo sapiens_hsa000710.38456032
78HTLV-I infection_Homo sapiens_hsa051660.37705019
79Oocyte meiosis_Homo sapiens_hsa041140.35689300
80Viral carcinogenesis_Homo sapiens_hsa052030.34583744
81Phenylalanine metabolism_Homo sapiens_hsa003600.33847294
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33473497
83Systemic lupus erythematosus_Homo sapiens_hsa053220.32511898
84Primary immunodeficiency_Homo sapiens_hsa053400.32360798
85Arachidonic acid metabolism_Homo sapiens_hsa005900.31963267
86Sulfur metabolism_Homo sapiens_hsa009200.31753967
87Chemical carcinogenesis_Homo sapiens_hsa052040.31457929
88Regulation of autophagy_Homo sapiens_hsa041400.31169411
89Primary bile acid biosynthesis_Homo sapiens_hsa001200.30840470
90Arginine and proline metabolism_Homo sapiens_hsa003300.30028125
91Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.26483512
92Propanoate metabolism_Homo sapiens_hsa006400.26311575
93Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.25467768
94Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25422488
95Apoptosis_Homo sapiens_hsa042100.24298860
96N-Glycan biosynthesis_Homo sapiens_hsa005100.22165582
97Intestinal immune network for IgA production_Homo sapiens_hsa046720.21686027
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.20372349
99Nitrogen metabolism_Homo sapiens_hsa009100.16433500
100Synaptic vesicle cycle_Homo sapiens_hsa047210.14499977
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.13562430
102Measles_Homo sapiens_hsa051620.13369416
103Tyrosine metabolism_Homo sapiens_hsa003500.12311879
104Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.12055662
105Acute myeloid leukemia_Homo sapiens_hsa052210.11532158
106Pentose and glucuronate interconversions_Homo sapiens_hsa000400.11115365
107beta-Alanine metabolism_Homo sapiens_hsa004100.10981089
108Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.10502597
109Peroxisome_Homo sapiens_hsa041460.10408636
110Circadian rhythm_Homo sapiens_hsa047100.10332327
111TGF-beta signaling pathway_Homo sapiens_hsa043500.09965513
112Influenza A_Homo sapiens_hsa051640.08577430
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.08379193
114SNARE interactions in vesicular transport_Homo sapiens_hsa041300.07894337
115Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.07321776
116Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.07165422
117Shigellosis_Homo sapiens_hsa051310.07163634
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07098198
119Small cell lung cancer_Homo sapiens_hsa052220.06517515
120Central carbon metabolism in cancer_Homo sapiens_hsa052300.06511702
121NF-kappa B signaling pathway_Homo sapiens_hsa040640.05750216
122Maturity onset diabetes of the young_Homo sapiens_hsa049500.04639223
123Other glycan degradation_Homo sapiens_hsa005110.04428487
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.04329842

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