TMEM131

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)5.06912515
2cytoplasmic mRNA processing body assembly (GO:0033962)4.32096059
3negative regulation of histone methylation (GO:0031061)4.29810109
4nuclear pore complex assembly (GO:0051292)4.24282320
5hypotonic response (GO:0006971)4.16014177
6mitotic sister chromatid cohesion (GO:0007064)4.09958271
7positive regulation of histone deacetylation (GO:0031065)3.94233206
8nuclear pore organization (GO:0006999)3.90906240
9heterochromatin organization (GO:0070828)3.86782776
10NLS-bearing protein import into nucleus (GO:0006607)3.69289943
11hemidesmosome assembly (GO:0031581)3.53306045
12pore complex assembly (GO:0046931)3.48570980
13skin morphogenesis (GO:0043589)3.48242332
14regulation of histone H3-K9 methylation (GO:0051570)3.42339173
15regulation of translational fidelity (GO:0006450)3.36612791
16protein localization to endosome (GO:0036010)3.18429745
17glucocorticoid receptor signaling pathway (GO:0042921)3.16793865
18RNA stabilization (GO:0043489)3.15830117
19mRNA stabilization (GO:0048255)3.15830117
20positive regulation of SMAD protein import into nucleus (GO:0060391)3.06359872
21cell adhesion mediated by integrin (GO:0033627)3.05683100
22embryonic process involved in female pregnancy (GO:0060136)3.04694567
23regulation of RNA export from nucleus (GO:0046831)3.04394214
24chromatin assembly (GO:0031497)2.99641724
25positive regulation of gene expression, epigenetic (GO:0045815)2.98511795
26histone H3-K9 demethylation (GO:0033169)2.97795510
27positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.91652904
28positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.91652904
29positive regulation of mitotic sister chromatid separation (GO:1901970)2.91652904
30receptor recycling (GO:0001881)2.88394871
31regulation of sister chromatid cohesion (GO:0007063)2.83223855
32response to UV-C (GO:0010225)2.82122398
33barbed-end actin filament capping (GO:0051016)2.81704342
34corticosteroid receptor signaling pathway (GO:0031958)2.81287431
35histone H3-K4 methylation (GO:0051568)2.80240428
36intracellular estrogen receptor signaling pathway (GO:0030520)2.78778443
37regulation of DNA endoreduplication (GO:0032875)2.78465171
38sister chromatid segregation (GO:0000819)2.75886919
39peptidyl-lysine dimethylation (GO:0018027)2.74708506
40positive regulation of mRNA catabolic process (GO:0061014)2.74093836
41mesodermal cell differentiation (GO:0048333)2.73220527
42desmosome organization (GO:0002934)2.70635709
43determination of adult lifespan (GO:0008340)2.70374151
44positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.67207762
45regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.67207762
46negative regulation of chromatin modification (GO:1903309)2.64822258
47regulation of extracellular matrix disassembly (GO:0010715)2.64451475
48regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.64167513
49positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.64167513
50stress fiber assembly (GO:0043149)2.62972738
51histone H2A monoubiquitination (GO:0035518)2.62193889
52positive regulation of protein deacetylation (GO:0090312)2.60824688
53regulation of NFAT protein import into nucleus (GO:0051532)2.60801390
54regulation of mRNA catabolic process (GO:0061013)2.59196736
55positive regulation of erythrocyte differentiation (GO:0045648)2.58398579
56insulin-like growth factor receptor signaling pathway (GO:0048009)2.58109213
57negative regulation of histone modification (GO:0031057)2.57090059
58COPII vesicle coating (GO:0048208)2.56908856
59negative regulation of translation, ncRNA-mediated (GO:0040033)2.56722580
60regulation of translation, ncRNA-mediated (GO:0045974)2.56722580
61negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.56722580
62regulation of stem cell maintenance (GO:2000036)2.56187989
63cytoskeletal anchoring at plasma membrane (GO:0007016)2.55723068
64histone H3-K36 demethylation (GO:0070544)2.55022396
65regulation of SMAD protein import into nucleus (GO:0060390)2.54018009
66apoptotic process involved in morphogenesis (GO:0060561)2.52757679
67protein localization to kinetochore (GO:0034501)2.52506388
68mitotic nuclear envelope disassembly (GO:0007077)2.51997969
69regulation of erythrocyte differentiation (GO:0045646)2.51399052
70negative regulation of anoikis (GO:2000811)2.50579262
71histone H3-K4 trimethylation (GO:0080182)2.49694805
72histone lysine demethylation (GO:0070076)2.49403450
73regulation of mitotic spindle organization (GO:0060236)2.49204264
74response to laminar fluid shear stress (GO:0034616)2.49139769
75adherens junction assembly (GO:0034333)2.48756065
76dosage compensation (GO:0007549)2.48621493
77regulation of nucleobase-containing compound transport (GO:0032239)2.48528900
78negative regulation of erythrocyte differentiation (GO:0045647)2.47108642
79DNA duplex unwinding (GO:0032508)2.47089418
80negative regulation of DNA repair (GO:0045738)2.46556080
81positive regulation of chromosome segregation (GO:0051984)2.46386798
82DNA geometric change (GO:0032392)2.45593861
83trophectodermal cell differentiation (GO:0001829)2.45459746
84gene silencing (GO:0016458)2.44401405
85mitotic G1 DNA damage checkpoint (GO:0031571)2.44030821
86hippo signaling (GO:0035329)2.42978106
87COPI coating of Golgi vesicle (GO:0048205)2.42478004
88Golgi transport vesicle coating (GO:0048200)2.42478004
89histone lysine methylation (GO:0034968)2.42307737
90regulation of histone H3-K4 methylation (GO:0051569)2.41254493
91membrane disassembly (GO:0030397)2.41097153
92nuclear envelope disassembly (GO:0051081)2.41097153
93positive regulation of extracellular matrix organization (GO:1903055)2.40990046
94positive regulation of RNA splicing (GO:0033120)2.40806613
95regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.40699415
96focal adhesion assembly (GO:0048041)2.39453637
97cell-substrate adherens junction assembly (GO:0007045)2.39453637
98germinal center formation (GO:0002467)2.39444310
99embryonic hemopoiesis (GO:0035162)2.39049907
100protein localization to chromosome, centromeric region (GO:0071459)2.38009285
101gene silencing by RNA (GO:0031047)2.37698532
102peptidyl-lysine trimethylation (GO:0018023)2.36983367
103L-alpha-amino acid transmembrane transport (GO:1902475)2.36918111
104pinocytosis (GO:0006907)2.36279593
105regulation of gamma-delta T cell differentiation (GO:0045586)2.35513796
106mitotic sister chromatid segregation (GO:0000070)2.35234353
107mammary gland epithelial cell proliferation (GO:0033598)2.34667983
108positive regulation of gamma-delta T cell activation (GO:0046645)2.34665253
109DNA unwinding involved in DNA replication (GO:0006268)2.33954505
110regulation of gene silencing by RNA (GO:0060966)2.33883905
111regulation of posttranscriptional gene silencing (GO:0060147)2.33883905
112regulation of gene silencing by miRNA (GO:0060964)2.33883905
113anterior/posterior axis specification, embryo (GO:0008595)2.33500824
114mitotic chromosome condensation (GO:0007076)2.32412721
115growth hormone receptor signaling pathway (GO:0060396)2.32151069
116negative regulation of fatty acid transport (GO:2000192)2.31684386
117regulation of translational termination (GO:0006449)2.31411419
118regulation of histone methylation (GO:0031060)2.30332594
119histone demethylation (GO:0016577)2.30194840
120negative regulation of gene silencing (GO:0060969)2.29817358
121regulation of histone H3-K27 methylation (GO:0061085)2.29634402
122cell-substrate junction assembly (GO:0007044)2.29629608
123regulation of chromatin silencing (GO:0031935)2.28755055
124histone H4-K12 acetylation (GO:0043983)2.28673992
125regulation of necroptotic process (GO:0060544)2.28176044
126positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.27265870
127positive regulation of Cdc42 GTPase activity (GO:0043089)2.24670712
128membrane protein ectodomain proteolysis (GO:0006509)2.23953368
129cortical actin cytoskeleton organization (GO:0030866)2.23630041
130antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.22528855
131regulation of early endosome to late endosome transport (GO:2000641)2.21940104
132coronary vasculature morphogenesis (GO:0060977)2.21347732
133definitive hemopoiesis (GO:0060216)2.19922860
134regulation of cholesterol homeostasis (GO:2000188)2.19756640
135peptidyl-threonine modification (GO:0018210)2.18644508
136endodermal cell differentiation (GO:0035987)2.17777820
137membrane raft organization (GO:0031579)2.17335069
138negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.15757085
139maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.15350819
140regulation of extracellular matrix organization (GO:1903053)2.14399068
141bundle of His cell to Purkinje myocyte communication (GO:0086069)2.13385805
142peptidyl-threonine phosphorylation (GO:0018107)2.11831992
143regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.10042822
144negative regulation of myotube differentiation (GO:0010832)2.09948007
145antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.09757489
146dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.09436547
147gland morphogenesis (GO:0022612)2.09053149
148vesicle coating (GO:0006901)2.08017886
149lipid translocation (GO:0034204)2.07631522
150phospholipid translocation (GO:0045332)2.07631522
151semaphorin-plexin signaling pathway (GO:0071526)2.07547768
152pericardium development (GO:0060039)2.06436455
153negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.05759417
154protein retention in ER lumen (GO:0006621)2.05710249
155regulation of ARF protein signal transduction (GO:0032012)2.05547925
156response to muramyl dipeptide (GO:0032495)2.04753653
157embryonic camera-type eye morphogenesis (GO:0048596)2.04575363
158mannose metabolic process (GO:0006013)2.04441272
159chondrocyte development (GO:0002063)2.04284507
160negative regulation of protein localization to plasma membrane (GO:1903077)2.03863074
161detection of molecule of bacterial origin (GO:0032490)2.03817778
162iron ion import (GO:0097286)2.03010385
163phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.02909996
164regulation of anoikis (GO:2000209)2.02568200
165epithelial cell-cell adhesion (GO:0090136)2.02376947
166regulation of lipid kinase activity (GO:0043550)2.01977833
167positive regulation of blood vessel endothelial cell migration (GO:0043536)2.01233714
168cortical cytoskeleton organization (GO:0030865)1.99949610
169basement membrane organization (GO:0071711)1.99343526
170detection of other organism (GO:0098543)1.98754794
171surfactant homeostasis (GO:0043129)1.98632192
172antigen processing and presentation of endogenous antigen (GO:0019883)1.97716470
173endocytic recycling (GO:0032456)1.97434536
174substrate-dependent cell migration (GO:0006929)1.97051386
175positive regulation of cellular amide metabolic process (GO:0034250)1.95824372
176SMAD protein complex assembly (GO:0007183)1.94608434
177cellular response to fluid shear stress (GO:0071498)1.94094193
178positive regulation of membrane protein ectodomain proteolysis (GO:0051044)1.93719528
179regulation of transforming growth factor beta2 production (GO:0032909)1.93703227
180embryonic retina morphogenesis in camera-type eye (GO:0060059)1.93282417
181negative regulation of keratinocyte proliferation (GO:0010839)1.91989023
182activation of Rac GTPase activity (GO:0032863)1.90790486
183response to fluid shear stress (GO:0034405)1.90772631
184planar cell polarity pathway involved in neural tube closure (GO:0090179)1.90420621
185positive regulation of receptor recycling (GO:0001921)1.88819141

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.06210435
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.81366328
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.58391920
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.06906115
5MYC_22102868_ChIP-Seq_BL_Human3.66099119
6GATA1_22025678_ChIP-Seq_K562_Human2.65714269
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.47761716
8* TCF7_22412390_ChIP-Seq_EML_Mouse2.44257037
9SMAD_19615063_ChIP-ChIP_OVARY_Human2.31594383
10KDM2B_26808549_Chip-Seq_DND41_Human2.30869689
11KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.23019817
12KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.18347760
13VDR_21846776_ChIP-Seq_THP-1_Human2.13975370
14KDM2B_26808549_Chip-Seq_SUP-B15_Human2.06590098
15SALL1_21062744_ChIP-ChIP_HESCs_Human1.99761580
16FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.98794831
17SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.94522174
18TP63_17297297_ChIP-ChIP_HaCaT_Human1.92856492
19E2F4_17652178_ChIP-ChIP_JURKAT_Human1.90686546
20SCL_19346495_ChIP-Seq_HPC-7_Human1.87634673
21TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.86377444
22MAF_26560356_Chip-Seq_TH1_Human1.86317031
23ZNF217_24962896_ChIP-Seq_MCF-7_Human1.83278819
24Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.81232956
25STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.79468826
26ELK3_25401928_ChIP-Seq_HUVEC_Human1.79432186
27SOX9_24532713_ChIP-Seq_HFSC_Mouse1.77602564
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.72717148
29TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.72283389
30GATA1_19941826_ChIP-Seq_K562_Human1.71265787
31CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.70886346
32* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.70293550
33* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.69046923
34ZFP281_27345836_Chip-Seq_ESCs_Mouse1.68203615
35SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.68041134
36CTNNB1_20460455_ChIP-Seq_HCT116_Human1.66672525
37ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.66529083
38UTX_26944678_Chip-Seq_JUKART_Human1.65952860
39KDM2B_26808549_Chip-Seq_JURKAT_Human1.61396281
40* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.60182705
41BP1_19119308_ChIP-ChIP_Hs578T_Human1.60101452
42RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.58700342
43SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.58054250
44SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.58054250
45* FOXA2_19822575_ChIP-Seq_HepG2_Human1.57801587
46TRIM28_21343339_ChIP-Seq_HEK293_Human1.57173192
47ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.56689607
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.54398167
49ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.53710423
50RARG_19884340_ChIP-ChIP_MEFs_Mouse1.53374362
51ESR1_20079471_ChIP-ChIP_T-47D_Human1.52171410
52DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.52018523
53* GATA1_19941827_ChIP-Seq_MEL_Mouse1.51858957
54IRF8_22096565_ChIP-ChIP_GC-B_Human1.50908362
55NCOR1_26117541_ChIP-Seq_K562_Human1.50125669
56NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.49070175
57P300_27058665_Chip-Seq_ZR-75-30cells_Human1.48719292
58GATA2_21666600_ChIP-Seq_HMVEC_Human1.47510483
59CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47436971
60SOX2_27498859_Chip-Seq_STOMACH_Mouse1.47122785
61NFIB_24661679_ChIP-Seq_LUNG_Mouse1.46973347
62ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.46355295
63ZFP281_18757296_ChIP-ChIP_E14_Mouse1.45693409
64MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.45395001
65PPAR_26484153_Chip-Seq_NCI-H1993_Human1.44196246
66SALL4_18804426_ChIP-ChIP_XEN_Mouse1.42884320
67STAT6_21828071_ChIP-Seq_BEAS2B_Human1.42476258
68TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.41867540
69KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.41412829
70* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.40152858
71TBX20_22080862_ChIP-Seq_HEART_Mouse1.39676238
72TBX20_22328084_ChIP-Seq_HEART_Mouse1.39676238
73E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.38090076
74NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.38018269
75* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37629791
76EP300_21415370_ChIP-Seq_HL-1_Mouse1.37280573
77KDM2B_26808549_Chip-Seq_K562_Human1.36544287
78E2F1_21310950_ChIP-Seq_MCF-7_Human1.35899655
79EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35833228
80FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.35817762
81SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.35195372
82MYB_26560356_Chip-Seq_TH1_Human1.35134620
83TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.34597903
84FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.33999179
85STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.32879215
86PKCTHETA_26484144_Chip-Seq_BREAST_Human1.30758053
87ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.30694389
88VDR_24787735_ChIP-Seq_THP-1_Human1.30486476
89* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.30485863
90MYB_26560356_Chip-Seq_TH2_Human1.30085484
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29203503
92SPI1_23127762_ChIP-Seq_K562_Human1.28216466
93VDR_24763502_ChIP-Seq_THP-1_Human1.27707865
94* CIITA_25753668_ChIP-Seq_RAJI_Human1.27082170
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.26358642
96TP63_19390658_ChIP-ChIP_HaCaT_Human1.26292100
97* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.25071557
98WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.21798985
99THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.21622491
100GATA6_25053715_ChIP-Seq_YYC3_Human1.20661692
101WT1_19549856_ChIP-ChIP_CCG9911_Human1.20131468
102ATF3_27146783_Chip-Seq_COLON_Human1.19658148
103TCF4_18268006_ChIP-ChIP_LS174T_Human1.18761997
104NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.18435346
105RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.18380591
106* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.18226795
107* RACK7_27058665_Chip-Seq_MCF-7_Human1.18011799
108TP53_16413492_ChIP-PET_HCT116_Human1.17836787
109* BRD4_25478319_ChIP-Seq_HGPS_Human1.16922305
110HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15120043
111AHR_22903824_ChIP-Seq_MCF-7_Human1.13919351
112PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13297955
113KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.12815927
114KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.12815927
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.12815927
116HIF1A_21447827_ChIP-Seq_MCF-7_Human1.11837889
117LXR_22158963_ChIP-Seq_LIVER_Mouse1.11508039
118ESR1_15608294_ChIP-ChIP_MCF-7_Human1.11407306
119RUNX_20019798_ChIP-Seq_JUKART_Human1.11277635
120UBF1/2_26484160_Chip-Seq_HMECs_Human1.11210471
121FOXO3_23340844_ChIP-Seq_DLD1_Human1.11000617
122MYB_21317192_ChIP-Seq_ERMYB_Mouse1.10347707
123IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.09914303
124POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09848118
125CHD1_26751641_Chip-Seq_LNCaP_Human1.07843478
126VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.07087891
127ZNF263_19887448_ChIP-Seq_K562_Human1.06436474
128RUNX1_22412390_ChIP-Seq_EML_Mouse1.05940714
129FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.05918214
130* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.05850888
131GATA1_22383799_ChIP-Seq_G1ME_Mouse1.05452096
132GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04270519
133CJUN_26792858_Chip-Seq_BT549_Human1.03660795
134NANOG_21062744_ChIP-ChIP_HESCs_Human1.03429241
135CREB1_26743006_Chip-Seq_LNCaP_Human1.03094413
136NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.03017815
137RUNX1_27514584_Chip-Seq_MCF-7_Human1.02991384
138GATA2_19941826_ChIP-Seq_K562_Human1.02245685
139STAT3_1855785_ChIP-Seq_MESCs_Mouse1.02109069
140FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.01488591
141CDX2_20551321_ChIP-Seq_CACO-2_Human1.00889386
142IRF8_27001747_Chip-Seq_BMDM_Mouse0.98908700
143MAF_26560356_Chip-Seq_TH2_Human0.98676032
144TFEB_21752829_ChIP-Seq_HELA_Human0.97902273
145ESR1_21235772_ChIP-Seq_MCF-7_Human0.96982042
146CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.95955368
147SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.95677071
148FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95335294
149CLOCK_20551151_ChIP-Seq_293T_Human0.94884647
150* TP63_23658742_ChIP-Seq_EP156T_Human0.94222924

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.88160803
2MP0003705_abnormal_hypodermis_morpholog3.80712443
3MP0005076_abnormal_cell_differentiation3.45731373
4MP0008438_abnormal_cutaneous_collagen3.23184881
5MP0005409_darkened_coat_color3.05396144
6MP0003300_gastrointestinal_ulcer2.87791268
7MP0010307_abnormal_tumor_latency2.75375397
8MP0005451_abnormal_body_composition2.68960149
9MP0000569_abnormal_digit_pigmentation2.46159209
10MP0005275_abnormal_skin_tensile2.29610755
11MP0009278_abnormal_bone_marrow2.21221001
12MP0003566_abnormal_cell_adhesion2.15904347
13MP0003303_peritoneal_inflammation2.13254606
14MP0003111_abnormal_nucleus_morphology2.07343739
15MP0002877_abnormal_melanocyte_morpholog1.98158293
16MP0010234_abnormal_vibrissa_follicle1.92401283
17MP0004272_abnormal_basement_membrane1.86800252
18MP0001545_abnormal_hematopoietic_system1.86118658
19MP0005397_hematopoietic_system_phenotyp1.86118658
20MP0002009_preneoplasia1.81206024
21MP0004197_abnormal_fetal_growth/weight/1.81086027
22MP0010094_abnormal_chromosome_stability1.75482750
23MP0004808_abnormal_hematopoietic_stem1.73328430
24MP0008057_abnormal_DNA_replication1.72603469
25MP0002086_abnormal_extraembryonic_tissu1.68053352
26MP0000733_abnormal_muscle_development1.67583949
27MP0005257_abnormal_intraocular_pressure1.66825680
28MP0003191_abnormal_cellular_cholesterol1.64649340
29MP0001958_emphysema1.60904187
30MP0003183_abnormal_peptide_metabolism1.60566572
31MP0003077_abnormal_cell_cycle1.59260754
32MP0000350_abnormal_cell_proliferation1.57861183
33MP0004264_abnormal_extraembryonic_tissu1.56050490
34MP0002084_abnormal_developmental_patter1.53021066
35MP0003984_embryonic_growth_retardation1.52178909
36MP0002088_abnormal_embryonic_growth/wei1.51259131
37MP0003436_decreased_susceptibility_to1.50833428
38MP0008961_abnormal_basal_metabolism1.49902553
39MP0001730_embryonic_growth_arrest1.49179437
40MP0003950_abnormal_plasma_membrane1.48299867
41MP0001672_abnormal_embryogenesis/_devel1.47371720
42MP0005380_embryogenesis_phenotype1.47371720
43MP0003828_pulmonary_edema1.45017491
44MP0001849_ear_inflammation1.43911123
45MP0002896_abnormal_bone_mineralization1.43807088
46MP0003045_fibrosis1.43252540
47MP0002060_abnormal_skin_morphology1.42278021
48MP0005623_abnormal_meninges_morphology1.41684442
49MP0002396_abnormal_hematopoietic_system1.40275782
50MP0003787_abnormal_imprinting1.36447228
51MP0004233_abnormal_muscle_weight1.36038416
52MP0002925_abnormal_cardiovascular_devel1.34175402
53MP0002398_abnormal_bone_marrow1.33742471
54MP0003172_abnormal_lysosome_physiology1.33470341
55MP0005023_abnormal_wound_healing1.33196877
56MP0002796_impaired_skin_barrier1.30268671
57MP0005058_abnormal_lysosome_morphology1.30100259
58MP0001697_abnormal_embryo_size1.29768918
59MP0004957_abnormal_blastocyst_morpholog1.28934575
60MP0002085_abnormal_embryonic_tissue1.28738248
61MP0003091_abnormal_cell_migration1.28464004
62MP0002166_altered_tumor_susceptibility1.28165914
63MP0002998_abnormal_bone_remodeling1.27811576
64MP0004185_abnormal_adipocyte_glucose1.26831224
65MP0003123_paternal_imprinting1.26415739
66MP0001915_intracranial_hemorrhage1.25992618
67MP0004510_myositis1.25932667
68MP0003279_aneurysm1.25314970
69MP0000751_myopathy1.23057637
70MP0001800_abnormal_humoral_immune1.21303911
71MP0010368_abnormal_lymphatic_system1.20916130
72MP0009703_decreased_birth_body1.20771345
73MP0000703_abnormal_thymus_morphology1.19652283
74MP0004858_abnormal_nervous_system1.19204762
75MP0003868_abnormal_feces_composition1.17735237
76MP0009780_abnormal_chondrocyte_physiolo1.17579382
77MP0006054_spinal_hemorrhage1.15239929
78MP0002080_prenatal_lethality1.14800211
79MP0002722_abnormal_immune_system1.14712729
80MP0000490_abnormal_crypts_of1.14030225
81MP0008770_decreased_survivor_rate1.13949457
82MP0004947_skin_inflammation1.09885988
83MP0008260_abnormal_autophagy1.09512442
84MP0003121_genomic_imprinting1.09007030
85MP0000685_abnormal_immune_system1.07486114
86MP0002006_tumorigenesis1.07215272
87MP0000767_abnormal_smooth_muscle1.05203263
88MP0003656_abnormal_erythrocyte_physiolo1.04933637
89MP0003453_abnormal_keratinocyte_physiol1.03883918
90MP0000266_abnormal_heart_morphology1.02731312
91MP0003890_abnormal_embryonic-extraembry1.02629785
92MP0010630_abnormal_cardiac_muscle1.01956463
93MP0000428_abnormal_craniofacial_morphol0.99850017
94MP0002168_other_aberrant_phenotype0.97627748
95MP0001293_anophthalmia0.97196132
96MP0000689_abnormal_spleen_morphology0.96903481
97MP0010678_abnormal_skin_adnexa0.96148602
98MP0001790_abnormal_immune_system0.93587207
99MP0005387_immune_system_phenotype0.93587207
100MP0009672_abnormal_birth_weight0.93250699
101MP0004087_abnormal_muscle_fiber0.93109789
102MP0005164_abnormal_response_to0.93064714
103MP0003448_altered_tumor_morphology0.92571615
104MP0008004_abnormal_stomach_pH0.92070110
105MP0000858_altered_metastatic_potential0.90361627
106MP0001533_abnormal_skeleton_physiology0.90315548
107MP0003567_abnormal_fetal_cardiomyocyte0.89907332
108MP0005310_abnormal_salivary_gland0.89765143
109MP0001216_abnormal_epidermal_layer0.89703993
110MP0003693_abnormal_embryo_hatching0.89218033
111MP0001784_abnormal_fluid_regulation0.89095471
112MP0002452_abnormal_antigen_presenting0.89080317
113MP0009053_abnormal_anal_canal0.88877321
114MP0000313_abnormal_cell_death0.88617003
115MP0003935_abnormal_craniofacial_develop0.87813383
116MP0008877_abnormal_DNA_methylation0.87719550
117MP0002019_abnormal_tumor_incidence0.87647406
118MP0009115_abnormal_fat_cell0.86909243
119MP0008007_abnormal_cellular_replicative0.86850367
120MP0000716_abnormal_immune_system0.85924238
121MP0002971_abnormal_brown_adipose0.85719893
122MP0001851_eye_inflammation0.84776343
123MP0002429_abnormal_blood_cell0.84740681
124MP0005464_abnormal_platelet_physiology0.84467346
125MP0003763_abnormal_thymus_physiology0.84178627
126MP0005621_abnormal_cell_physiology0.82907650
127MP0001666_abnormal_nutrient_absorption0.82805105
128MP0003119_abnormal_digestive_system0.82378372
129MP0005375_adipose_tissue_phenotype0.82145265
130MP0010155_abnormal_intestine_physiology0.81369626
131MP0002092_abnormal_eye_morphology0.81273804
132MP0000432_abnormal_head_morphology0.80742748
133MP0005187_abnormal_penis_morphology0.80622487
134MP0001835_abnormal_antigen_presentation0.80247558
135MP0000759_abnormal_skeletal_muscle0.80155292
136MP0009384_cardiac_valve_regurgitation0.78937466
137MP0003115_abnormal_respiratory_system0.78438488
138MP0009840_abnormal_foam_cell0.78196550
139MP0002697_abnormal_eye_size0.78018051
140MP0005666_abnormal_adipose_tissue0.77362499
141MP0002089_abnormal_postnatal_growth/wei0.77140688
142MP0000477_abnormal_intestine_morphology0.77114146
143MP0000537_abnormal_urethra_morphology0.76934687
144MP0002419_abnormal_innate_immunity0.76866183
145MP0000003_abnormal_adipose_tissue0.75939521
146MP0006138_congestive_heart_failure0.74824186
147MP0005025_abnormal_response_to0.69333456
148MP0003941_abnormal_skin_development0.69236088
149MP0005501_abnormal_skin_physiology0.69149545
150MP0000627_abnormal_mammary_gland0.68289286
151MP0005503_abnormal_tendon_morphology0.65880103
152MP0000579_abnormal_nail_morphology0.65262617

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)3.76476292
2Macroorchidism (HP:0000053)3.29706137
3Short 4th metacarpal (HP:0010044)3.19198940
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.19198940
5Arterial tortuosity (HP:0005116)3.17219862
6Heterotopia (HP:0002282)3.15432009
7Flat acetabular roof (HP:0003180)3.04191569
8Vascular tortuosity (HP:0004948)3.02686393
9Atrophic scars (HP:0001075)2.81671385
10Volvulus (HP:0002580)2.79844959
11Premature rupture of membranes (HP:0001788)2.75574850
12Aortic dissection (HP:0002647)2.70067106
13Cerebral aneurysm (HP:0004944)2.69404603
14Long eyelashes (HP:0000527)2.64223269
15Abnormality of the astrocytes (HP:0100707)2.56319228
16Astrocytoma (HP:0009592)2.56319228
17Prominent nose (HP:0000448)2.53848027
18Ependymoma (HP:0002888)2.52341943
19Hyperacusis (HP:0010780)2.51022696
20Poikilocytosis (HP:0004447)2.44596785
21Neoplasm of the oral cavity (HP:0100649)2.44537305
22Broad palm (HP:0001169)2.44016339
23Right ventricular cardiomyopathy (HP:0011663)2.39694079
24Malignant gastrointestinal tract tumors (HP:0006749)2.35953899
25Gastrointestinal carcinoma (HP:0002672)2.35953899
26Abnormality of the 4th metacarpal (HP:0010012)2.35472496
27Peritonitis (HP:0002586)2.34151808
28Shallow orbits (HP:0000586)2.31739780
29Osteolytic defects of the phalanges of the hand (HP:0009771)2.30788385
30Osteolytic defects of the hand bones (HP:0009699)2.30788385
31Increased nuchal translucency (HP:0010880)2.26636179
32Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.23862706
33Supernumerary ribs (HP:0005815)2.21929876
34Trigonocephaly (HP:0000243)2.21480813
35Exercise-induced myalgia (HP:0003738)2.17082751
36Urethral obstruction (HP:0000796)2.16951865
37Transitional cell carcinoma of the bladder (HP:0006740)2.16945197
38Enlarged penis (HP:0000040)2.16306685
39Narrow palate (HP:0000189)2.15817928
40Neonatal short-limb short stature (HP:0008921)2.13891589
41Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.12203000
42Leiomyosarcoma (HP:0100243)2.11912576
43Uterine leiomyosarcoma (HP:0002891)2.11912576
44Glioma (HP:0009733)2.10732437
45Increased variability in muscle fiber diameter (HP:0003557)2.10303660
46Spondylolisthesis (HP:0003302)2.09449802
47Centrally nucleated skeletal muscle fibers (HP:0003687)2.08747454
48Absent frontal sinuses (HP:0002688)2.08341363
49Cervical subluxation (HP:0003308)2.07438795
50Overgrowth (HP:0001548)2.07209688
51Reticulocytosis (HP:0001923)2.06626382
52Type 1 muscle fiber predominance (HP:0003803)2.05803835
53Truncal obesity (HP:0001956)2.05459587
54Medulloblastoma (HP:0002885)2.04218610
55Ankyloglossia (HP:0010296)2.04124329
56Autoimmune thrombocytopenia (HP:0001973)2.03583659
57Rectal prolapse (HP:0002035)2.02429466
58Bladder carcinoma (HP:0002862)2.00125922
59Bladder neoplasm (HP:0009725)2.00125922
60Fragile skin (HP:0001030)1.99675490
61Bilateral sensorineural hearing impairment (HP:0008619)1.99045859
62Wormian bones (HP:0002645)1.98155271
63Advanced eruption of teeth (HP:0006288)1.97516356
64Deviation of the thumb (HP:0009603)1.97293289
65Abnormality of skeletal muscle fiber size (HP:0012084)1.97125145
66Increased density of long bones (HP:0006392)1.96048003
67Eczematoid dermatitis (HP:0000976)1.93945640
68Thin bony cortex (HP:0002753)1.93890983
69Mitral stenosis (HP:0001718)1.93692628
70Deep venous thrombosis (HP:0002625)1.93122404
71Broad thumb (HP:0011304)1.92960080
72Dysmetric saccades (HP:0000641)1.91929460
73Natal tooth (HP:0000695)1.91461988
74Mitral valve prolapse (HP:0001634)1.88985658
75Basal cell carcinoma (HP:0002671)1.87711765
76Milia (HP:0001056)1.87070673
77Neoplasm of striated muscle (HP:0009728)1.85776640
78Increased connective tissue (HP:0009025)1.85416973
79Abnormality of carpal bone ossification (HP:0006257)1.85407398
80Broad face (HP:0000283)1.85082460
81Papillary thyroid carcinoma (HP:0002895)1.84978058
82Proximal placement of thumb (HP:0009623)1.84953692
83Skin tags (HP:0010609)1.84815740
84Subacute progressive viral hepatitis (HP:0006572)1.84197815
85Aortic aneurysm (HP:0004942)1.83344959
86Deep philtrum (HP:0002002)1.82621736
87Aneurysm (HP:0002617)1.81631432
88Dislocated radial head (HP:0003083)1.80581704
89Vertebral compression fractures (HP:0002953)1.80499043
90Asymmetry of the thorax (HP:0001555)1.79938031
91Polycythemia (HP:0001901)1.79871888
92Obsessive-compulsive behavior (HP:0000722)1.79732244
93Supernumerary bones of the axial skeleton (HP:0009144)1.79651351
94Abnormal ossification of hand bones (HP:0005921)1.79239898
95Abnormality of the acetabulum (HP:0003170)1.78407964
96Mitral regurgitation (HP:0001653)1.77405888
97Obstructive sleep apnea (HP:0002870)1.77178775
98Genu recurvatum (HP:0002816)1.76693276
99Hyperkalemia (HP:0002153)1.76005210
100Blue sclerae (HP:0000592)1.74983016
101Short 5th finger (HP:0009237)1.74648375
102Joint laxity (HP:0001388)1.73405852
103Spinal rigidity (HP:0003306)1.73183217
104Abnormality of the nasal septum (HP:0000419)1.72799961
105Acanthocytosis (HP:0001927)1.72333740
106Skull defect (HP:0001362)1.71792301
107Anal stenosis (HP:0002025)1.71176723
108Dilatation of the ascending aorta (HP:0005111)1.70740547
109Recurrent viral infections (HP:0004429)1.69679894
110Overlapping toe (HP:0001845)1.69607686
111Short middle phalanx of the 5th finger (HP:0004220)1.69384600
112Cupped ribs (HP:0000887)1.69118346
113Abnormality of the thoracic spine (HP:0100711)1.68633447
114Limited elbow extension (HP:0001377)1.68511154
115Alopecia of scalp (HP:0002293)1.68454720
116Syringomyelia (HP:0003396)1.66810172
117Spinal cord lesions (HP:0100561)1.66810172
118Ulnar bowing (HP:0003031)1.66770702
119Thoracolumbar scoliosis (HP:0002944)1.66539907
120Coarse hair (HP:0002208)1.66051109
121Biliary tract neoplasm (HP:0100574)1.65879931
122Short phalanx of the thumb (HP:0009660)1.65349862
123Abnormality of the distal phalanx of the thumb (HP:0009617)1.64944247
124Abnormality of oral frenula (HP:0000190)1.64882755
125Smooth philtrum (HP:0000319)1.64676505
126Renal duplication (HP:0000075)1.63829939
127Uterine neoplasm (HP:0010784)1.63727669
128Short nail (HP:0001799)1.63669679
129Low anterior hairline (HP:0000294)1.63231392
130High pitched voice (HP:0001620)1.63151565
131Bladder diverticulum (HP:0000015)1.62968218
132Cellulitis (HP:0100658)1.62834378
133Pseudobulbar signs (HP:0002200)1.62479764
134Lymphangioma (HP:0100764)1.62329589
135Thick nail (HP:0001805)1.62123917
136Vertebral arch anomaly (HP:0008438)1.61408769
137Abnormality of the peritoneum (HP:0002585)1.61406541
138Disproportionate tall stature (HP:0001519)1.59874491
139Cutis marmorata (HP:0000965)1.59712274
140Ulnar deviation of the wrist (HP:0003049)1.59308949
141Abnormality of the lumbar spine (HP:0100712)1.59243853
142Abnormality of the radial head (HP:0003995)1.58967848
143Hemorrhage of the eye (HP:0011885)1.58911298
144Asymmetric septal hypertrophy (HP:0001670)1.58313734
145Mildly elevated creatine phosphokinase (HP:0008180)1.57690058
146Neoplasm of the heart (HP:0100544)1.56938846
147Gingivitis (HP:0000230)1.56432254
148Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.56299213
149Ectopic kidney (HP:0000086)1.55413392
150Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.55316869
151Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.54645432
152Abnormal number of incisors (HP:0011064)1.54299756
153Rhabdomyosarcoma (HP:0002859)1.54102912
154Upper limb amyotrophy (HP:0009129)1.53883142
155Distal upper limb amyotrophy (HP:0007149)1.53883142
156Hyporeflexia of lower limbs (HP:0002600)1.53426162
157Tibial bowing (HP:0002982)1.53199982
158Abnormal hand bone ossification (HP:0010660)1.53084512
159Mucopolysacchariduria (HP:0008155)1.53053330
160Urinary glycosaminoglycan excretion (HP:0003541)1.53053330
161Insomnia (HP:0100785)1.52849999
162Depressed nasal tip (HP:0000437)1.52634732
163Hematochezia (HP:0002573)1.52615112
164Protrusio acetabuli (HP:0003179)1.51833976
165Renovascular hypertension (HP:0100817)1.51449336
166Colitis (HP:0002583)1.51113665
167Ankle contracture (HP:0006466)1.51099080
168Distal lower limb amyotrophy (HP:0008944)1.51054697
169Fatigue (HP:0012378)1.49441160
170Cafe-au-lait spot (HP:0000957)1.48820911
171Achilles tendon contracture (HP:0001771)1.48778354
172Bowel diverticulosis (HP:0005222)1.48276447
173Scanning speech (HP:0002168)1.47398146
174Difficulty running (HP:0009046)1.46764693
175Abnormality of the Achilles tendon (HP:0005109)1.46657382
176Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.45248164
177Emphysema (HP:0002097)1.44470655

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.50251608
2TRIB33.24947703
3PKN23.21773386
4MAP3K103.01625925
5PRPF4B2.81136929
6EEF2K2.80924205
7BRD42.17807376
8ERN12.11436628
9CAMK1D2.05888255
10MAP4K11.88923519
11CAMK1G1.80533249
12CDK61.70916523
13BMX1.70030300
14CDC71.64465011
15MAP3K141.63932221
16ALK1.63359790
17NEK91.62659275
18PTK61.62343647
19MST1R1.62041545
20STK101.59315243
21ICK1.58907087
22LATS11.55328453
23NEK21.53730239
24MTOR1.53293328
25MAP3K131.50424633
26RIPK11.49624155
27TAOK11.43206927
28SIK11.39733662
29MAP3K21.38719768
30SMG11.36234525
31STK31.33274324
32PDGFRA1.30269430
33STK41.29054427
34JAK11.26919962
35TRPM71.26337202
36RIPK41.25892858
37SIK21.25767170
38CDK41.20730124
39FGFR31.20519842
40AKT31.20261491
41TTN1.18246684
42SCYL21.18237922
43LRRK21.10885124
44MET1.08552120
45MAP2K31.05679444
46DMPK1.02178470
47PTK21.00060298
48CHUK0.98139830
49LATS20.97120232
50MARK20.96230608
51SGK30.95656617
52MAP3K70.95542870
53PDGFRB0.95128193
54EPHB10.94730048
55PIM10.94557950
56EPHA20.92042345
57JAK30.91989309
58PIK3CG0.91343165
59MAPK110.89035116
60YES10.88428313
61MAP3K80.88343887
62FGFR40.87964711
63SGK20.87259982
64TYK20.86865477
65CDK90.83387474
66CHEK10.82282104
67MAP3K30.81353238
68RET0.80648799
69STK380.80394047
70MAP3K10.80164885
71CDC42BPA0.79184301
72GRK60.78604097
73NLK0.78495312
74JAK20.78212605
75FGFR10.77215969
76ATR0.75731554
77MOS0.75508677
78RPS6KB20.74399954
79PRKCH0.72713995
80TAOK30.71612958
81TTK0.70909135
82KSR10.70642522
83BLK0.70612230
84ATM0.68890358
85HCK0.68684307
86PAK20.68592994
87RPS6KA20.67098176
88DYRK1B0.66925193
89CDK20.65612900
90LMTK20.64335560
91MAP3K60.64321893
92WNK10.63406678
93NTRK10.63010861
94CDK70.61898752
95RPS6KA40.61399049
96EPHA30.60370187
97CLK10.57758306
98TYRO30.57415534
99STK240.57404218
100CSK0.56410391
101CSNK1D0.55812044
102MAPK70.53930399
103CSF1R0.53440360
104PDPK10.53346892
105DDR20.53337670
106HIPK20.53118950
107IRAK30.52578864
108CHEK20.51793586
109PRKAA20.51701569
110PRKDC0.51562994
111MAPK10.51459258
112PRKD20.50849165
113MAPK140.50833396
114PIK3CA0.50666022
115TGFBR20.50660494
116ROCK20.49473648
117AKT10.49220410
118PAK40.49195565
119RPS6KL10.48886100
120RPS6KC10.48886100
121SIK30.48142809
122SYK0.46099474
123TBK10.45837556
124KSR20.45829399
125EGFR0.44516257
126PDK10.44232009
127FLT30.44097286
128MELK0.43441945
129RPS6KA10.42824724
130CDK10.42767924
131SGK2230.41655162
132SGK4940.41655162
133ERBB20.41354299
134TAOK20.41255058
135ZAP700.41054370
136GSK3B0.40449188
137IKBKB0.40374699
138IKBKE0.40371863
139NEK10.40356277
140CAMK40.40156617
141MAP3K90.40082616
142BTK0.39357115
143MAPK100.39301057
144OBSCN0.38256445
145PRKD30.38224857

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052201.87451520
2Lysine degradation_Homo sapiens_hsa003101.75044631
3Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.67536386
4mTOR signaling pathway_Homo sapiens_hsa041501.67189241
5B cell receptor signaling pathway_Homo sapiens_hsa046621.61997026
6MicroRNAs in cancer_Homo sapiens_hsa052061.58369011
7Adherens junction_Homo sapiens_hsa045201.56655146
8Small cell lung cancer_Homo sapiens_hsa052221.44293854
9Acute myeloid leukemia_Homo sapiens_hsa052211.40778137
10Endometrial cancer_Homo sapiens_hsa052131.40333369
11Non-small cell lung cancer_Homo sapiens_hsa052231.38064893
12Proteoglycans in cancer_Homo sapiens_hsa052051.37962736
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.36939762
14Thyroid hormone signaling pathway_Homo sapiens_hsa049191.32388714
15Notch signaling pathway_Homo sapiens_hsa043301.31649231
16Dorso-ventral axis formation_Homo sapiens_hsa043201.30118637
17Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.27918642
18Colorectal cancer_Homo sapiens_hsa052101.27658703
19Viral myocarditis_Homo sapiens_hsa054161.27593796
20Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.27385072
21Neurotrophin signaling pathway_Homo sapiens_hsa047221.24583709
22Other glycan degradation_Homo sapiens_hsa005111.24384542
23Pancreatic cancer_Homo sapiens_hsa052121.22349962
24Primary immunodeficiency_Homo sapiens_hsa053401.21514585
25Toxoplasmosis_Homo sapiens_hsa051451.20379709
26Osteoclast differentiation_Homo sapiens_hsa043801.20307519
27mRNA surveillance pathway_Homo sapiens_hsa030151.18918749
28AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16691468
29Leishmaniasis_Homo sapiens_hsa051401.13012116
30Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.11969820
31Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11434192
32HTLV-I infection_Homo sapiens_hsa051661.11268047
33Glioma_Homo sapiens_hsa052141.11235208
34Hepatitis B_Homo sapiens_hsa051611.10299070
35Viral carcinogenesis_Homo sapiens_hsa052031.09917785
36Insulin resistance_Homo sapiens_hsa049311.09468665
37Type II diabetes mellitus_Homo sapiens_hsa049301.08770072
38NF-kappa B signaling pathway_Homo sapiens_hsa040641.08564467
39Focal adhesion_Homo sapiens_hsa045101.07755525
40Herpes simplex infection_Homo sapiens_hsa051681.06074299
41Measles_Homo sapiens_hsa051621.04944371
42Prostate cancer_Homo sapiens_hsa052151.04125482
43Basal cell carcinoma_Homo sapiens_hsa052171.01738736
44Apoptosis_Homo sapiens_hsa042101.00414470
45Longevity regulating pathway - mammal_Homo sapiens_hsa042110.99945885
46Central carbon metabolism in cancer_Homo sapiens_hsa052300.99661932
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98940860
48Bladder cancer_Homo sapiens_hsa052190.98053562
49p53 signaling pathway_Homo sapiens_hsa041150.97906762
50T cell receptor signaling pathway_Homo sapiens_hsa046600.97020143
51Cell cycle_Homo sapiens_hsa041100.96682099
52Leukocyte transendothelial migration_Homo sapiens_hsa046700.96362744
53Jak-STAT signaling pathway_Homo sapiens_hsa046300.95621300
54Thyroid cancer_Homo sapiens_hsa052160.95403151
55Influenza A_Homo sapiens_hsa051640.94822206
56Renal cell carcinoma_Homo sapiens_hsa052110.92784851
57VEGF signaling pathway_Homo sapiens_hsa043700.92553274
58Platelet activation_Homo sapiens_hsa046110.92067975
59FoxO signaling pathway_Homo sapiens_hsa040680.91203766
60GnRH signaling pathway_Homo sapiens_hsa049120.90646457
61Hippo signaling pathway_Homo sapiens_hsa043900.89792260
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87751812
63Hematopoietic cell lineage_Homo sapiens_hsa046400.87574364
64Regulation of actin cytoskeleton_Homo sapiens_hsa048100.87241666
65HIF-1 signaling pathway_Homo sapiens_hsa040660.87126371
66Toll-like receptor signaling pathway_Homo sapiens_hsa046200.86417406
67TNF signaling pathway_Homo sapiens_hsa046680.86056574
68Prolactin signaling pathway_Homo sapiens_hsa049170.86004066
69Glycosaminoglycan degradation_Homo sapiens_hsa005310.85304365
70Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85184713
71Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.84407186
72Dilated cardiomyopathy_Homo sapiens_hsa054140.83710945
73Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.83291442
74Pathways in cancer_Homo sapiens_hsa052000.82219628
75Insulin signaling pathway_Homo sapiens_hsa049100.80959320
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.80858140
77AMPK signaling pathway_Homo sapiens_hsa041520.80836283
78Estrogen signaling pathway_Homo sapiens_hsa049150.80673546
79Amoebiasis_Homo sapiens_hsa051460.80124651
80Antigen processing and presentation_Homo sapiens_hsa046120.78584068
81Staphylococcus aureus infection_Homo sapiens_hsa051500.78553255
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77647385
83Intestinal immune network for IgA production_Homo sapiens_hsa046720.77217672
84Chemokine signaling pathway_Homo sapiens_hsa040620.76686569
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.74983439
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.74558858
87RNA transport_Homo sapiens_hsa030130.73995723
88TGF-beta signaling pathway_Homo sapiens_hsa043500.73434079
89Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72582118
90Complement and coagulation cascades_Homo sapiens_hsa046100.72430070
91Carbohydrate digestion and absorption_Homo sapiens_hsa049730.71488945
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.71108563
93ErbB signaling pathway_Homo sapiens_hsa040120.70384037
94Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.70310412
95MAPK signaling pathway_Homo sapiens_hsa040100.69969076
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68884554
97ECM-receptor interaction_Homo sapiens_hsa045120.68316101
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67646610
99Long-term potentiation_Homo sapiens_hsa047200.66974604
100Protein digestion and absorption_Homo sapiens_hsa049740.66728403
101Wnt signaling pathway_Homo sapiens_hsa043100.66402534
102Inositol phosphate metabolism_Homo sapiens_hsa005620.65231439
103Choline metabolism in cancer_Homo sapiens_hsa052310.64847863
104Tuberculosis_Homo sapiens_hsa051520.64629608
105RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64222698
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.63434949
107Shigellosis_Homo sapiens_hsa051310.62456969
108Endocytosis_Homo sapiens_hsa041440.62205584
109NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60795087
110Rap1 signaling pathway_Homo sapiens_hsa040150.60722872
111One carbon pool by folate_Homo sapiens_hsa006700.60514984
112Malaria_Homo sapiens_hsa051440.60385927
113Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.59616116
114Nitrogen metabolism_Homo sapiens_hsa009100.59580782
115Prion diseases_Homo sapiens_hsa050200.59262945
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58803574
117Hepatitis C_Homo sapiens_hsa051600.58399758
118Hedgehog signaling pathway_Homo sapiens_hsa043400.57746562
119Lysosome_Homo sapiens_hsa041420.57744949
120Non-homologous end-joining_Homo sapiens_hsa034500.57542296
121Renin-angiotensin system_Homo sapiens_hsa046140.57512144
122Pertussis_Homo sapiens_hsa051330.56136410
123Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55666575
124PI3K-Akt signaling pathway_Homo sapiens_hsa041510.55344068
125Sphingolipid metabolism_Homo sapiens_hsa006000.54343462
126Glucagon signaling pathway_Homo sapiens_hsa049220.52694758

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