TMEM132C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lateral sprouting from an epithelium (GO:0060601)6.49967264
2planar cell polarity pathway involved in neural tube closure (GO:0090179)5.06315795
3cell proliferation involved in metanephros development (GO:0072203)4.74645553
4regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.63893064
5viral transcription (GO:0019083)4.47839045
6mesenchymal cell proliferation (GO:0010463)4.44178522
7lung-associated mesenchyme development (GO:0060484)4.41953700
8regulation of branching involved in prostate gland morphogenesis (GO:0060687)4.22669814
9bone trabecula formation (GO:0060346)4.22174865
10regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)4.21157505
11translational termination (GO:0006415)4.21154060
12outer ear morphogenesis (GO:0042473)4.13398186
13hindlimb morphogenesis (GO:0035137)4.06541195
14craniofacial suture morphogenesis (GO:0097094)4.03688983
15midbrain development (GO:0030901)4.02578614
16embryonic hindlimb morphogenesis (GO:0035116)3.98583544
17G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.92857745
18cell proliferation involved in kidney development (GO:0072111)3.92653149
19endocardial cushion morphogenesis (GO:0003203)3.91641937
20establishment of tissue polarity (GO:0007164)3.83502592
21establishment of planar polarity (GO:0001736)3.83502592
22paraxial mesoderm development (GO:0048339)3.82617288
23mesenchymal-epithelial cell signaling (GO:0060638)3.79841995
24protein heterotrimerization (GO:0070208)3.79111862
25sequestering of extracellular ligand from receptor (GO:0035581)3.78934333
26mesenchyme morphogenesis (GO:0072132)3.78860210
27neuron projection extension involved in neuron projection guidance (GO:1902284)3.76761949
28axon extension involved in axon guidance (GO:0048846)3.76761949
29presynaptic membrane assembly (GO:0097105)3.74656267
30embryonic forelimb morphogenesis (GO:0035115)3.71610986
31somite development (GO:0061053)3.61961012
32proximal/distal pattern formation (GO:0009954)3.58018959
33negative regulation of DNA repair (GO:0045738)3.57385060
34regulation of non-canonical Wnt signaling pathway (GO:2000050)3.56667509
35Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.54818710
36presynaptic membrane organization (GO:0097090)3.54516837
37negative regulation of axon extension involved in axon guidance (GO:0048843)3.54108680
38head development (GO:0060322)3.52447495
39convergent extension (GO:0060026)3.47994304
40cranial suture morphogenesis (GO:0060363)3.46272074
41axonal fasciculation (GO:0007413)3.46087348
42neuronal stem cell maintenance (GO:0097150)3.43188541
43forelimb morphogenesis (GO:0035136)3.41556932
44otic vesicle formation (GO:0030916)3.39588431
45negative regulation of catenin import into nucleus (GO:0035414)3.36930384
46cotranslational protein targeting to membrane (GO:0006613)3.36185421
47regulation of establishment of planar polarity (GO:0090175)3.35583008
48low-density lipoprotein particle clearance (GO:0034383)3.34659212
49cochlea morphogenesis (GO:0090103)3.34009244
50SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.32592606
51endothelial cell chemotaxis (GO:0035767)3.32031969
52postsynaptic membrane organization (GO:0001941)3.29746389
53protein targeting to ER (GO:0045047)3.28215548
54negative regulation of axon guidance (GO:1902668)3.27741526
55organ formation (GO:0048645)3.27018377
56limb bud formation (GO:0060174)3.26521455
57epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.26403909
58embryonic appendage morphogenesis (GO:0035113)3.26110044
59embryonic limb morphogenesis (GO:0030326)3.26110044
60embryonic skeletal joint morphogenesis (GO:0060272)3.25735644
61camera-type eye morphogenesis (GO:0048593)3.24070160
62translational elongation (GO:0006414)3.22961071
63axis elongation (GO:0003401)3.21287115
64non-canonical Wnt signaling pathway (GO:0035567)3.17654837
65positive regulation of smoothened signaling pathway (GO:0045880)3.16468295
66pyrimidine nucleobase catabolic process (GO:0006208)3.16315152
67cellular protein complex disassembly (GO:0043624)3.15860556
68negative regulation of embryonic development (GO:0045992)3.15251205
69positive regulation of vascular permeability (GO:0043117)3.14355631
70neuron recognition (GO:0008038)3.12656214
71appendage morphogenesis (GO:0035107)3.12543102
72limb morphogenesis (GO:0035108)3.12543102
73establishment of protein localization to endoplasmic reticulum (GO:0072599)3.12491030
74regulation of axon guidance (GO:1902667)3.11058329
75embryonic cranial skeleton morphogenesis (GO:0048701)3.10572790
76nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.09557387
77regulation of organ formation (GO:0003156)3.08601653
78artery development (GO:0060840)3.07868193
79branch elongation of an epithelium (GO:0060602)3.06621300
80ribosomal small subunit assembly (GO:0000028)3.06473207
81mesonephros development (GO:0001823)3.06448640
82positive regulation of gastrulation (GO:2000543)3.05388578
83dendritic spine morphogenesis (GO:0060997)3.04927645
84embryonic digit morphogenesis (GO:0042733)3.02257290
85protein localization to endoplasmic reticulum (GO:0070972)3.01063465
86sequestering of actin monomers (GO:0042989)3.00234964
87spinal cord development (GO:0021510)2.99390340
88metanephros development (GO:0001656)2.93270685
89viral life cycle (GO:0019058)2.93069777
90embryonic skeletal system development (GO:0048706)2.90444682
91embryonic retina morphogenesis in camera-type eye (GO:0060059)2.90168701
92positive regulation of synapse assembly (GO:0051965)2.87650045
93dorsal/ventral axis specification (GO:0009950)2.86813441
94establishment of nucleus localization (GO:0040023)2.86548019
95prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.84795670
96anatomical structure regression (GO:0060033)2.84549512
97cellular response to monoamine stimulus (GO:0071868)2.83927920
98cellular response to catecholamine stimulus (GO:0071870)2.83927920
99neuron fate determination (GO:0048664)2.83262872
100neuronal ion channel clustering (GO:0045161)2.82874108
101regulation of mesenchymal cell apoptotic process (GO:2001053)2.82055650
102organ induction (GO:0001759)2.81819692
103regulation of axon extension involved in axon guidance (GO:0048841)2.81475934
104midgut development (GO:0007494)2.80619900
105regulation of heart morphogenesis (GO:2000826)2.80377505
106extracellular negative regulation of signal transduction (GO:1900116)2.80293113
107extracellular regulation of signal transduction (GO:1900115)2.80293113
108retinal ganglion cell axon guidance (GO:0031290)2.78719457
109protein complex disassembly (GO:0043241)2.77861327
110mesenchyme development (GO:0060485)2.77134766
111lens fiber cell development (GO:0070307)2.75819376
112regulation of somitogenesis (GO:0014807)2.75267706
113short-term memory (GO:0007614)2.74984119
114peripheral nervous system axon ensheathment (GO:0032292)2.74637710
115myelination in peripheral nervous system (GO:0022011)2.74637710
116negative chemotaxis (GO:0050919)2.74605222
117type B pancreatic cell development (GO:0003323)2.73702723
118hippo signaling (GO:0035329)2.73610591
119epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.73443334
120respiratory tube development (GO:0030323)2.73143049
121notochord development (GO:0030903)2.72699537
122regulation of cAMP-dependent protein kinase activity (GO:2000479)2.71147831
123positive regulation of mesenchymal cell proliferation (GO:0002053)2.70514881
124palate development (GO:0060021)2.70339345
125embryonic foregut morphogenesis (GO:0048617)2.69347671
126cell migration in hindbrain (GO:0021535)2.69104337
127cartilage morphogenesis (GO:0060536)2.68904189
128negative regulation of chondrocyte differentiation (GO:0032331)2.68523910
129prostate gland epithelium morphogenesis (GO:0060740)2.67213976
130polarized epithelial cell differentiation (GO:0030859)2.67060511
131regulation of mesenchymal cell proliferation (GO:0010464)2.66316728
132thalamus development (GO:0021794)2.66248680
133radial glial cell differentiation (GO:0060019)2.65546422
134mesenchymal cell differentiation (GO:0048762)2.65022981
135regulation of transforming growth factor beta2 production (GO:0032909)2.63574152
136regulation of smoothened signaling pathway (GO:0008589)2.63187775
137cell migration involved in heart development (GO:0060973)2.63070633
138renal system development (GO:0072001)2.62665531
139eyelid development in camera-type eye (GO:0061029)2.62453993
140embryonic digestive tract morphogenesis (GO:0048557)2.61654127
141male genitalia development (GO:0030539)2.60941063
142regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.60568045
143lung epithelium development (GO:0060428)2.59880953
144regulation of mesoderm development (GO:2000380)2.59843195
145positive regulation of epithelial to mesenchymal transition (GO:0010718)2.59520698
146regulation of sister chromatid cohesion (GO:0007063)2.58973573
147branching involved in salivary gland morphogenesis (GO:0060445)2.58695275
148somatic stem cell division (GO:0048103)2.58298832
149cell surface receptor signaling pathway involved in heart development (GO:0061311)2.56514787
150dopaminergic neuron differentiation (GO:0071542)2.55763938
151vasculature development (GO:0001944)2.55333841
152macromolecular complex disassembly (GO:0032984)2.55314471
153metanephric mesenchyme development (GO:0072075)2.55108851
154Notch signaling involved in heart development (GO:0061314)2.55036204
155vocalization behavior (GO:0071625)2.53262621
156epithelial cilium movement (GO:0003351)2.51337371
157regulation of glycogen (starch) synthase activity (GO:2000465)2.49870280
158response to catecholamine (GO:0071869)2.49850278
159response to monoamine (GO:0071867)2.49850278
160cellular response to epinephrine stimulus (GO:0071872)2.48835175
161transmission of nerve impulse (GO:0019226)2.48430664
162skeletal muscle organ development (GO:0060538)2.48216292
163limb development (GO:0060173)2.46613727
164appendage development (GO:0048736)2.46613727
165kidney morphogenesis (GO:0060993)2.45300949
166tongue development (GO:0043586)2.44284410
167regulation of sequestering of triglyceride (GO:0010889)2.43287132
168auditory behavior (GO:0031223)2.41226845
169ionotropic glutamate receptor signaling pathway (GO:0035235)2.40936317
170negative regulation of vascular permeability (GO:0043116)2.40364700
171protein targeting to membrane (GO:0006612)2.39227868
172cGMP biosynthetic process (GO:0006182)2.38936516

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.02734565
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.69863811
3EZH2_22144423_ChIP-Seq_EOC_Human3.34196543
4EED_16625203_ChIP-ChIP_MESCs_Mouse3.20050785
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.97769627
6* EZH2_27304074_Chip-Seq_ESCs_Mouse2.95916087
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87651054
8TP63_19390658_ChIP-ChIP_HaCaT_Human2.84915295
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.83293148
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.76621694
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.76621694
12PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.68958532
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.66892137
14* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.60277311
15BMI1_23680149_ChIP-Seq_NPCS_Mouse2.55322151
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.55118768
17SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.41293637
18RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.37189730
19* CBX2_27304074_Chip-Seq_ESCs_Mouse2.36354432
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.32921657
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.32366548
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.29587914
23GBX2_23144817_ChIP-Seq_PC3_Human2.28743747
24SALL1_21062744_ChIP-ChIP_HESCs_Human2.14210759
25POU5F1_16153702_ChIP-ChIP_HESCs_Human2.02358415
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.79681451
27TP53_20018659_ChIP-ChIP_R1E_Mouse1.79537616
28FOXM1_23109430_ChIP-Seq_U2OS_Human1.77257052
29EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.75643767
30PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.73552287
31ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.73186845
32* EZH2_27294783_Chip-Seq_ESCs_Mouse1.69415503
33WT1_19549856_ChIP-ChIP_CCG9911_Human1.69095463
34FUS_26573619_Chip-Seq_HEK293_Human1.68692030
35RNF2_27304074_Chip-Seq_NSC_Mouse1.63234948
36NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.62847481
37RING1B_27294783_Chip-Seq_NPCs_Mouse1.61676022
38ISL1_27105846_Chip-Seq_CPCs_Mouse1.61060427
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57530220
40CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.53892241
41SUZ12_27294783_Chip-Seq_ESCs_Mouse1.50945071
42* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50330386
43CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.50174735
44RING1B_27294783_Chip-Seq_ESCs_Mouse1.47754257
45WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.45429361
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.45391934
47STAT6_21828071_ChIP-Seq_BEAS2B_Human1.43788457
48TAF15_26573619_Chip-Seq_HEK293_Human1.41258899
49DROSHA_22980978_ChIP-Seq_HELA_Human1.40934304
50* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.40311851
51AR_21572438_ChIP-Seq_LNCaP_Human1.37790894
52KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.37065319
53EWS_26573619_Chip-Seq_HEK293_Human1.36958153
54* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.36857338
55NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.33462590
56* REST_21632747_ChIP-Seq_MESCs_Mouse1.32840321
57TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31055277
58OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.30878132
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.30502960
60* P300_19829295_ChIP-Seq_ESCs_Human1.29780566
61SOX2_16153702_ChIP-ChIP_HESCs_Human1.29050064
62ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28506908
63* SMAD4_21799915_ChIP-Seq_A2780_Human1.26324778
64AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24514673
65TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23236150
66* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.22892221
67* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22272609
68ZFP281_18757296_ChIP-ChIP_E14_Mouse1.19470152
69ZFP57_27257070_Chip-Seq_ESCs_Mouse1.18657279
70POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17949534
71GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17263041
72SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.16232458
73TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15710990
74* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15294228
75CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14414364
76MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14050248
77TRIM28_21343339_ChIP-Seq_HEK293_Human1.13283957
78TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.12770052
79ERG_21242973_ChIP-ChIP_JURKAT_Human1.12686175
80LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11752689
81CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.10138735
82STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09478268
83FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.08546318
84YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08537919
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08403130
86HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08237752
87EP300_21415370_ChIP-Seq_HL-1_Mouse1.07853924
88CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07630946
89* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.06720019
90* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05955552
91KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.05475883
92TBX3_20139965_ChIP-Seq_ESCs_Mouse1.04393909
93* SMAD3_21741376_ChIP-Seq_EPCs_Human1.04169098
94SOX9_26525672_Chip-Seq_HEART_Mouse1.04020070
95TBX3_20139965_ChIP-Seq_MESCs_Mouse1.03886770
96* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.02996236
97SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02282916
98REST_18959480_ChIP-ChIP_MESCs_Mouse1.01554644
99PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.01442062
100WT1_25993318_ChIP-Seq_PODOCYTE_Human1.01375407
101ARNT_22903824_ChIP-Seq_MCF-7_Human1.01080727
102IKZF1_21737484_ChIP-ChIP_HCT116_Human1.00497210
103RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99455651
104CDX2_19796622_ChIP-Seq_MESCs_Mouse0.98973269
105* POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97833794
106* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97833794
107AHR_22903824_ChIP-Seq_MCF-7_Human0.97423438
108GATA1_26923725_Chip-Seq_HPCs_Mouse0.97294687
109TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96500973
110AR_19668381_ChIP-Seq_PC3_Human0.96216523
111RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.95834187
112VDR_22108803_ChIP-Seq_LS180_Human0.95501051
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.95087582
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93931291
115ZFP281_27345836_Chip-Seq_ESCs_Mouse0.93926757
116SMAD_19615063_ChIP-ChIP_OVARY_Human0.93862918
117ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93774064
118* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.93453116
119* TP53_18474530_ChIP-ChIP_U2OS_Human0.93441213
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92453295
121MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.92113854
122SOX2_21211035_ChIP-Seq_LN229_Gbm0.91937692
123CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.91220880
124SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.90594710
125* AR_25329375_ChIP-Seq_VCAP_Human0.90352717
126EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.88896753

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting4.11933884
2MP0009053_abnormal_anal_canal3.29372846
3MP0003123_paternal_imprinting3.22418158
4MP0000537_abnormal_urethra_morphology3.09128409
5MP0009379_abnormal_foot_pigmentation3.02890501
6MP0010030_abnormal_orbit_morphology2.98850087
7MP0003136_yellow_coat_color2.83771225
8MP0005503_abnormal_tendon_morphology2.75050797
9MP0000566_synostosis2.72568378
10MP0009250_abnormal_appendicular_skeleto2.67897189
11MP0003121_genomic_imprinting2.67434588
12MP0003385_abnormal_body_wall2.54400232
13MP0002938_white_spotting2.54155507
14MP0002102_abnormal_ear_morphology2.52630043
15MP0005670_abnormal_white_adipose2.48981235
16MP0002282_abnormal_trachea_morphology2.38624971
17MP0003942_abnormal_urinary_system2.38403431
18MP0003937_abnormal_limbs/digits/tail_de2.34992525
19MP0000049_abnormal_middle_ear2.13965269
20MP0000534_abnormal_ureter_morphology2.05876407
21MP0008438_abnormal_cutaneous_collagen1.98529690
22MP0002249_abnormal_larynx_morphology1.95484955
23MP0005248_abnormal_Harderian_gland1.91829172
24MP0005187_abnormal_penis_morphology1.87485811
25MP0003755_abnormal_palate_morphology1.82091515
26MP0003938_abnormal_ear_development1.81205516
27MP0002638_abnormal_pupillary_reflex1.80882949
28MP0003011_delayed_dark_adaptation1.78147231
29MP0002932_abnormal_joint_morphology1.77465032
30MP0003115_abnormal_respiratory_system1.77283591
31MP0000428_abnormal_craniofacial_morphol1.74330722
32MP0005423_abnormal_somatic_nervous1.70905521
33MP0003283_abnormal_digestive_organ1.68192299
34MP0003878_abnormal_ear_physiology1.65750820
35MP0005377_hearing/vestibular/ear_phenot1.65750820
36MP0004272_abnormal_basement_membrane1.64969688
37MP0002116_abnormal_craniofacial_bone1.62274045
38MP0002233_abnormal_nose_morphology1.56360474
39MP0005666_abnormal_adipose_tissue1.55342584
40MP0003787_abnormal_imprinting1.55146070
41MP0001299_abnormal_eye_distance/1.54146252
42MP0002909_abnormal_adrenal_gland1.53677857
43MP0003935_abnormal_craniofacial_develop1.49696431
44MP0005367_renal/urinary_system_phenotyp1.48019772
45MP0000516_abnormal_urinary_system1.48019772
46MP0003119_abnormal_digestive_system1.47637714
47MP0001293_anophthalmia1.45672991
48MP0003315_abnormal_perineum_morphology1.43966007
49MP0004885_abnormal_endolymph1.38815651
50MP0005275_abnormal_skin_tensile1.37795635
51MP0002109_abnormal_limb_morphology1.37341253
52MP0000778_abnormal_nervous_system1.36737345
53MP0004130_abnormal_muscle_cell1.34795244
54MP0005508_abnormal_skeleton_morphology1.33034376
55MP0000762_abnormal_tongue_morphology1.30767798
56MP0002295_abnormal_pulmonary_circulatio1.30483113
57MP0000462_abnormal_digestive_system1.28088752
58MP0001346_abnormal_lacrimal_gland1.25972255
59MP0001984_abnormal_olfaction1.25588010
60MP0000579_abnormal_nail_morphology1.25278835
61MP0002971_abnormal_brown_adipose1.16389360
62MP0000432_abnormal_head_morphology1.14898457
63MP0002114_abnormal_axial_skeleton1.14119190
64MP0005375_adipose_tissue_phenotype1.13959410
65MP0001879_abnormal_lymphatic_vessel1.13083399
66MP0003861_abnormal_nervous_system1.11486255
67MP0002177_abnormal_outer_ear1.11444913
68MP0002063_abnormal_learning/memory/cond1.08779322
69MP0003941_abnormal_skin_development1.08714982
70MP0002751_abnormal_autonomic_nervous1.06827619
71MP0002115_abnormal_skeleton_extremities1.05684411
72MP0002653_abnormal_ependyma_morphology1.05626939
73MP0001486_abnormal_startle_reflex1.05477727
74MP0001340_abnormal_eyelid_morphology1.05151814
75MP0008877_abnormal_DNA_methylation1.04633946
76MP0001270_distended_abdomen1.04384665
77MP0002111_abnormal_tail_morphology1.03447767
78MP0002085_abnormal_embryonic_tissue1.02484282
79MP0001286_abnormal_eye_development1.02351385
80MP0004142_abnormal_muscle_tone1.02308996
81MP0002184_abnormal_innervation0.99902956
82MP0003959_abnormal_lean_body0.99888377
83MP0000163_abnormal_cartilage_morphology0.99866361
84MP0005257_abnormal_intraocular_pressure0.99644159
85MP0000733_abnormal_muscle_development0.98756503
86MP0000026_abnormal_inner_ear0.97695215
87MP0002108_abnormal_muscle_morphology0.97384845
88MP0000955_abnormal_spinal_cord0.95548442
89MP0004859_abnormal_synaptic_plasticity0.95287935
90MP0004270_analgesia0.95017061
91MP0004133_heterotaxia0.94034904
92MP0002572_abnormal_emotion/affect_behav0.93803639
93MP0008789_abnormal_olfactory_epithelium0.93420395
94MP0000631_abnormal_neuroendocrine_gland0.91966755
95MP0004233_abnormal_muscle_weight0.91589939
96MP0001177_atelectasis0.91058286
97MP0010368_abnormal_lymphatic_system0.90100103
98MP0005171_absent_coat_pigmentation0.89926520
99MP0002734_abnormal_mechanical_nocicepti0.89239771
100MP0009046_muscle_twitch0.88805532
101MP0002735_abnormal_chemical_nociception0.88752822
102MP0002084_abnormal_developmental_patter0.88608626
103MP0001485_abnormal_pinna_reflex0.86924777
104MP0002081_perinatal_lethality0.86389708
105MP0008932_abnormal_embryonic_tissue0.85830969
106MP0002064_seizures0.85449950
107MP0001440_abnormal_grooming_behavior0.85241443
108MP0006276_abnormal_autonomic_nervous0.84792560
109MP0003880_abnormal_central_pattern0.84552521
110MP0002557_abnormal_social/conspecific_i0.83919053
111MP0002876_abnormal_thyroid_physiology0.83306237
112MP0009745_abnormal_behavioral_response0.83263150
113MP0004145_abnormal_muscle_electrophysio0.83259057
114MP0002882_abnormal_neuron_morphology0.82092869
115MP0004197_abnormal_fetal_growth/weight/0.81015030
116MP0002822_catalepsy0.80366348
117MP0000751_myopathy0.79461440
118MP0002697_abnormal_eye_size0.78103377
119MP0002113_abnormal_skeleton_development0.76878274
120MP0004134_abnormal_chest_morphology0.75445168
121MP0003705_abnormal_hypodermis_morpholog0.73306141
122MP0003567_abnormal_fetal_cardiomyocyte0.72976456
123MP0000383_abnormal_hair_follicle0.72592432
124MP0001958_emphysema0.72513344
125MP0006292_abnormal_olfactory_placode0.71724174
126MP0005499_abnormal_olfactory_system0.71571088
127MP0005394_taste/olfaction_phenotype0.71571088
128MP0002089_abnormal_postnatal_growth/wei0.71465810
129MP0009703_decreased_birth_body0.71202521
130MP0002092_abnormal_eye_morphology0.70780783
131MP0002234_abnormal_pharynx_morphology0.70241726
132MP0003635_abnormal_synaptic_transmissio0.70054126
133MP0002152_abnormal_brain_morphology0.68557388
134MP0000767_abnormal_smooth_muscle0.67522380
135MP0004858_abnormal_nervous_system0.67239920
136MP0001175_abnormal_lung_morphology0.62170101

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)5.04407707
2Short 4th metacarpal (HP:0010044)5.04407707
3Abnormality of the parietal bone (HP:0002696)4.52170810
4Midline defect of the nose (HP:0004122)4.33507361
5Abnormality of the 4th metacarpal (HP:0010012)4.17145117
6Shallow orbits (HP:0000586)3.49657157
7Renal duplication (HP:0000075)3.28067322
8Split foot (HP:0001839)3.21146027
9Septo-optic dysplasia (HP:0100842)3.19942510
10Follicular hyperkeratosis (HP:0007502)3.09026805
11Focal motor seizures (HP:0011153)3.00251882
12Neonatal short-limb short stature (HP:0008921)2.99966487
13Broad toe (HP:0001837)2.99769079
14Partial duplication of thumb phalanx (HP:0009944)2.98483437
15Coronal craniosynostosis (HP:0004440)2.89245737
16Abnormality of the nasolacrimal system (HP:0000614)2.84482046
17Short middle phalanx of the 5th finger (HP:0004220)2.81823829
18Trigonocephaly (HP:0000243)2.77601693
19Partial duplication of the phalanx of hand (HP:0009999)2.77096653
20Abnormality of the phalanges of the hallux (HP:0010057)2.68167380
21Abnormality of the labia minora (HP:0012880)2.66021625
22Myokymia (HP:0002411)2.64742172
23Bronchomalacia (HP:0002780)2.64559923
24Abnormal number of incisors (HP:0011064)2.60986037
25Mesomelia (HP:0003027)2.54569551
26Microglossia (HP:0000171)2.50597775
27Bilateral microphthalmos (HP:0007633)2.50295027
28Abnormality of the phalanges of the 2nd finger (HP:0009541)2.49813271
29Narrow nasal bridge (HP:0000446)2.49492543
30Hepatoblastoma (HP:0002884)2.49259866
31Cutaneous finger syndactyly (HP:0010554)2.48933636
32Abnormality of the ischium (HP:0003174)2.46288941
33Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.45739432
34Anophthalmia (HP:0000528)2.44807303
35Ankle contracture (HP:0006466)2.41705906
36Abnormality of the distal phalanx of the thumb (HP:0009617)2.40840662
37Ulnar bowing (HP:0003031)2.40265457
38Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.40203755
39Deformed tarsal bones (HP:0008119)2.38192581
40Down-sloping shoulders (HP:0200021)2.37968511
41Stenosis of the external auditory canal (HP:0000402)2.37220552
42Rib fusion (HP:0000902)2.36150417
43Reticulocytopenia (HP:0001896)2.34940668
44Broad hallux (HP:0010055)2.34798787
45Broad metatarsal (HP:0001783)2.34163543
46Maternal diabetes (HP:0009800)2.30910643
47Abnormality of the 2nd finger (HP:0004100)2.30417328
48Preaxial foot polydactyly (HP:0001841)2.30302377
49Vertebral arch anomaly (HP:0008438)2.30300846
50Abnormality of the lacrimal duct (HP:0011481)2.28628486
51Vascular tortuosity (HP:0004948)2.27601347
52Abnormality of dentin (HP:0010299)2.27131692
53Bifid tongue (HP:0010297)2.25328960
54Hypoplasia of the ulna (HP:0003022)2.25287989
55Calcaneovalgus deformity (HP:0001848)2.25161778
56Congenital, generalized hypertrichosis (HP:0004540)2.22453437
57Broad thumb (HP:0011304)2.21802349
58Sleep apnea (HP:0010535)2.20301943
59Oligodactyly (hands) (HP:0001180)2.19958383
60Buphthalmos (HP:0000557)2.19710496
61Absent septum pellucidum (HP:0001331)2.18321912
62Diastasis recti (HP:0001540)2.17113952
63Abnormality of cells of the erythroid lineage (HP:0012130)2.17070121
64Hypoventilation (HP:0002791)2.15073302
65Cutaneous syndactyly (HP:0012725)2.14469477
66Oligomenorrhea (HP:0000876)2.13529094
67Nasolacrimal duct obstruction (HP:0000579)2.10326230
68Abnormality of the incisor (HP:0000676)2.08552923
69Sparse lateral eyebrow (HP:0005338)2.08344487
70Supernumerary ribs (HP:0005815)2.08329700
71Oligodactyly (HP:0012165)2.07622033
72Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.07119438
73Deviation of the hallux (HP:0010051)2.06768675
74Hypoplastic ischia (HP:0003175)2.03840503
75Pulmonary artery stenosis (HP:0004415)2.03410081
76Turricephaly (HP:0000262)2.03125399
77Tracheomalacia (HP:0002779)2.03083600
78Arterial tortuosity (HP:0005116)2.02155583
79Soft skin (HP:0000977)2.01718683
80Esophageal atresia (HP:0002032)2.01628448
81Abnormality of the diencephalon (HP:0010662)2.01620102
82Broad finger (HP:0001500)2.01489297
83Short phalanx of the thumb (HP:0009660)2.01072278
84Asymmetry of the thorax (HP:0001555)2.00457973
85Short 5th finger (HP:0009237)2.00033019
86Narrow palate (HP:0000189)2.00027112
87Bladder diverticulum (HP:0000015)1.98539936
88Broad phalanges of the hand (HP:0009768)1.98500819
89Anteriorly placed anus (HP:0001545)1.97729562
90Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.97700016
91Abnormal number of erythroid precursors (HP:0012131)1.97458776
92Shawl scrotum (HP:0000049)1.95295341
93Abnormality of the phalanges of the 5th finger (HP:0004213)1.95011634
94Broad phalanx (HP:0006009)1.93630079
95Vitreoretinal degeneration (HP:0000655)1.92874969
96Short hallux (HP:0010109)1.92674154
97Aplasia involving bones of the extremities (HP:0009825)1.92638133
98Aplasia involving bones of the upper limbs (HP:0009823)1.92638133
99Aplasia of the phalanges of the hand (HP:0009802)1.92638133
100Neoplasm of the heart (HP:0100544)1.92117456
101Abnormal respiratory motile cilium physiology (HP:0012261)1.91955099
102Broad long bones (HP:0005622)1.91020499
103Atonic seizures (HP:0010819)1.89929656
104Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.88889640
105Hallux valgus (HP:0001822)1.88303121
106Rhinitis (HP:0012384)1.88184331
107Humeroradial synostosis (HP:0003041)1.88148563
108Synostosis involving the elbow (HP:0003938)1.88148563
109Vertebral clefting (HP:0008428)1.86783969
110Hypoplastic labia majora (HP:0000059)1.85149072
111Supernumerary bones of the axial skeleton (HP:0009144)1.85116606
112Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.84359197
113Renovascular hypertension (HP:0100817)1.82846397
114Increased number of teeth (HP:0011069)1.82539621
115Prominent supraorbital ridges (HP:0000336)1.81807601
116Ectopia lentis (HP:0001083)1.79398955
117Chin dimple (HP:0010751)1.78963922
118Atresia of the external auditory canal (HP:0000413)1.78691157
119Mitral regurgitation (HP:0001653)1.77939798
120Abnormal eating behavior (HP:0100738)1.77594427
121Abnormality of the aortic arch (HP:0012303)1.77291065
122Choanal stenosis (HP:0000452)1.76976992
123Wide anterior fontanel (HP:0000260)1.76888537
124Aplasia/Hypoplasia of the ulna (HP:0006495)1.76763112
125Febrile seizures (HP:0002373)1.76713989
126Missing ribs (HP:0000921)1.76518431
127Protrusio acetabuli (HP:0003179)1.75207031
128Aplasia/Hypoplasia of the hallux (HP:0008362)1.74887452
129Bowing of the arm (HP:0006488)1.74813765
130Bowed forearm bones (HP:0003956)1.74813765
131Hypoplasia of the maxilla (HP:0000327)1.74650050
132Optic nerve hypoplasia (HP:0000609)1.74049300
133Aortic regurgitation (HP:0001659)1.73991383
134Abnormality of the septum pellucidum (HP:0007375)1.73667596
135Labial hypoplasia (HP:0000066)1.73336514
136Mitral valve prolapse (HP:0001634)1.73189804
137Acanthosis nigricans (HP:0000956)1.72821966
138Macrocytic anemia (HP:0001972)1.72033112
139Morphological abnormality of the middle ear (HP:0008609)1.71610945
140Slender build (HP:0001533)1.71606177
141Abnormality of incisor morphology (HP:0011063)1.71109612
142Broad distal phalanx of finger (HP:0009836)1.71108558
143Fibular hypoplasia (HP:0003038)1.71041456
144Sacral dimple (HP:0000960)1.70970027
145Bell-shaped thorax (HP:0001591)1.70400870
146Nephroblastoma (Wilms tumor) (HP:0002667)1.70013681
147Flat capital femoral epiphysis (HP:0003370)1.69259910
148Abnormality of the middle phalanges of the toes (HP:0010183)1.68800883
149Aplasia/Hypoplasia of metatarsal bones (HP:0001964)1.68273725
150Sprengel anomaly (HP:0000912)1.67451716
151Embryonal renal neoplasm (HP:0011794)1.67422190
152Abnormality of the labia majora (HP:0012881)1.67070433
153Intellectual disability, moderate (HP:0002342)1.67035681
154Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.66354219
155Omphalocele (HP:0001539)1.64091366
156Protruding ear (HP:0000411)1.63861506
157Concave nail (HP:0001598)1.63834172
158Abnormality of the middle phalanges of the hand (HP:0009833)1.62124353

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.06142878
2LATS23.62599459
3TNIK3.59954948
4EPHB23.31005742
5EPHA32.81043617
6NTRK12.59111049
7MKNK22.48841776
8KSR12.48479635
9MKNK12.38203251
10DDR22.37242873
11STK38L1.98991021
12CDK81.98335072
13FGFR21.96752190
14AKT31.87369916
15MAPK131.84874291
16TSSK61.78932386
17ERBB41.77889136
18MOS1.75172691
19PLK21.69785947
20CDC71.69459542
21MAP2K71.67103893
22MAP3K41.65220305
23PASK1.58930356
24PLK31.52411493
25CASK1.50775459
26NTRK31.50276926
27PRKD31.44013928
28SRPK11.37653225
29MAP3K121.34083302
30PDGFRA1.33411875
31NTRK21.31950410
32SIK31.24203022
33BUB11.20455143
34MAP3K101.20105448
35VRK21.19288135
36CAMK11.15939456
37MINK11.14137537
38STK31.10099920
39ERBB31.09668894
40MAPK151.07811869
41NEK91.06806518
42CDK51.03888431
43WNK31.03643098
44STK241.03282882
45TIE11.01942970
46RIPK11.01020944
47ROCK21.00134999
48ERBB20.99219034
49DMPK0.96970819
50FGFR10.94236484
51SGK20.93386882
52DYRK20.91446490
53MAP3K90.88843420
54TTK0.87207286
55CAMK1G0.86608830
56KSR20.84969190
57MAP2K40.83234245
58NEK10.82168703
59BMPR1B0.81484126
60MARK10.81389191
61STK110.79828143
62BCR0.79486212
63LRRK20.77244821
64TGFBR10.76795122
65PLK40.76343694
66SIK20.75946101
67PAK60.75860762
68MAPK70.75514677
69FER0.74665308
70WNK10.73945501
71PLK10.72413126
72LMTK20.72386554
73CAMK2B0.71592312
74PNCK0.70850651
75CHEK20.68964562
76TAF10.68962227
77MELK0.67238787
78YES10.67235479
79BRSK10.67043687
80CDK90.65471938
81CDK30.64848818
82NLK0.64585113
83PAK40.64078503
84CSNK1G10.63368217
85UHMK10.61806632
86GRK50.61453468
87PRKCH0.61080282
88CSNK1A1L0.60841479
89STK160.59628047
90PAK20.58039737
91CDK70.58039057
92NEK20.57631587
93CDK180.57272878
94CDK10.56727264
95ROCK10.56500775
96BRD40.56385940
97SIK10.56341651
98PRKCG0.56193060
99CDK120.55402258
100SGK30.55018219
101CDK140.54948234
102PRKCE0.54731664
103PRKCI0.54711982
104PKN10.54223532
105SGK4940.54169083
106SGK2230.54169083
107PAK30.54000448
108STK380.53483810
109LIMK10.53378486
110CSNK1G30.53173220
111PRKG10.52827297
112TRIB30.51794071
113PRKACB0.51777151
114PKN20.51358912
115MAPK40.51267637
116CHEK10.50995029
117BRSK20.48704315
118PDGFRB0.48568009
119CDK150.48070198
120CAMK1D0.47734687
121TLK10.47514716
122PTK60.47323201
123EPHA40.46656344
124BRAF0.46218623
125RPS6KA30.45306443
126CCNB10.43765543
127DYRK1A0.41835608
128CAMK2A0.41379724
129CDK11A0.41212724
130CSNK1G20.40735283
131PRKACG0.40675974
132ADRBK10.40372485
133ATM0.39786922
134PRKACA0.39161610
135VRK10.38314004
136PINK10.38296127
137AURKA0.38217031
138PRKCZ0.38138520
139CAMK2D0.38133719
140CDK20.37857480
141TYRO30.37720949
142CAMKK10.37136485
143IRAK20.36927217
144DAPK30.35004090
145MAP3K60.34881808
146RET0.34849520
147PRKAA10.33811033
148INSR0.33365207
149MAPK100.32146879

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052174.64907528
2Hedgehog signaling pathway_Homo sapiens_hsa043404.08171675
3Ribosome_Homo sapiens_hsa030103.69822611
4Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.67168275
5Hippo signaling pathway_Homo sapiens_hsa043902.60189895
6Wnt signaling pathway_Homo sapiens_hsa043102.25218425
7Nicotine addiction_Homo sapiens_hsa050332.23358716
8Cell cycle_Homo sapiens_hsa041102.07599028
9Melanogenesis_Homo sapiens_hsa049161.98659753
10TGF-beta signaling pathway_Homo sapiens_hsa043501.96338180
11Axon guidance_Homo sapiens_hsa043601.93791411
12Cardiac muscle contraction_Homo sapiens_hsa042601.91515955
13Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.85902186
14Colorectal cancer_Homo sapiens_hsa052101.72049224
15Alzheimers disease_Homo sapiens_hsa050101.68845080
16Oocyte meiosis_Homo sapiens_hsa041141.65333454
17Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.60690414
18Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.60363979
19Synaptic vesicle cycle_Homo sapiens_hsa047211.54085040
20Protein digestion and absorption_Homo sapiens_hsa049741.49321336
21Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.47416090
22ECM-receptor interaction_Homo sapiens_hsa045121.47187361
23GABAergic synapse_Homo sapiens_hsa047271.46638066
24mRNA surveillance pathway_Homo sapiens_hsa030151.44723499
25PPAR signaling pathway_Homo sapiens_hsa033201.44305943
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.44097828
27Endometrial cancer_Homo sapiens_hsa052131.42543308
28Melanoma_Homo sapiens_hsa052181.40269925
29Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.34802300
30Circadian entrainment_Homo sapiens_hsa047131.32424671
31Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.30258777
32Pathways in cancer_Homo sapiens_hsa052001.26888353
33Proteoglycans in cancer_Homo sapiens_hsa052051.25033700
34Adherens junction_Homo sapiens_hsa045201.24796611
35MicroRNAs in cancer_Homo sapiens_hsa052061.22937544
36Dopaminergic synapse_Homo sapiens_hsa047281.18975732
37Long-term depression_Homo sapiens_hsa047301.18823876
38Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.18800765
39Long-term potentiation_Homo sapiens_hsa047201.14528034
40Amphetamine addiction_Homo sapiens_hsa050311.14443644
41Taste transduction_Homo sapiens_hsa047421.14154952
42Gap junction_Homo sapiens_hsa045401.09138184
43Cocaine addiction_Homo sapiens_hsa050301.08372102
44Prostate cancer_Homo sapiens_hsa052151.08123426
45Notch signaling pathway_Homo sapiens_hsa043301.07678634
46Spliceosome_Homo sapiens_hsa030401.07547697
47Glutamatergic synapse_Homo sapiens_hsa047241.07172739
48Morphine addiction_Homo sapiens_hsa050321.03917512
49Glycerolipid metabolism_Homo sapiens_hsa005611.02497024
50Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.00995633
51Estrogen signaling pathway_Homo sapiens_hsa049150.99169068
52Nitrogen metabolism_Homo sapiens_hsa009100.97480944
53Vibrio cholerae infection_Homo sapiens_hsa051100.94262503
54Focal adhesion_Homo sapiens_hsa045100.94176269
55RNA transport_Homo sapiens_hsa030130.93336790
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.91988521
57HTLV-I infection_Homo sapiens_hsa051660.91011110
58Cholinergic synapse_Homo sapiens_hsa047250.90658344
59Collecting duct acid secretion_Homo sapiens_hsa049660.86811983
60Serotonergic synapse_Homo sapiens_hsa047260.84691620
61Renal cell carcinoma_Homo sapiens_hsa052110.84461712
62Tight junction_Homo sapiens_hsa045300.84452251
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82759156
64Dorso-ventral axis formation_Homo sapiens_hsa043200.81952346
65Glioma_Homo sapiens_hsa052140.81063797
66GnRH signaling pathway_Homo sapiens_hsa049120.80632468
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80135284
68ErbB signaling pathway_Homo sapiens_hsa040120.79849037
69Propanoate metabolism_Homo sapiens_hsa006400.78748775
70cGMP-PKG signaling pathway_Homo sapiens_hsa040220.78290834
71Alcoholism_Homo sapiens_hsa050340.76516643
72Histidine metabolism_Homo sapiens_hsa003400.76353406
73Aldosterone synthesis and secretion_Homo sapiens_hsa049250.75525011
74Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75407813
75RNA degradation_Homo sapiens_hsa030180.75300846
76cAMP signaling pathway_Homo sapiens_hsa040240.73978643
77Rap1 signaling pathway_Homo sapiens_hsa040150.73704107
78PI3K-Akt signaling pathway_Homo sapiens_hsa041510.73118694
79Basal transcription factors_Homo sapiens_hsa030220.72228888
80beta-Alanine metabolism_Homo sapiens_hsa004100.71321659
81Phenylalanine metabolism_Homo sapiens_hsa003600.71063319
82Gastric acid secretion_Homo sapiens_hsa049710.70463205
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.70432741
84Chronic myeloid leukemia_Homo sapiens_hsa052200.70207366
85Huntingtons disease_Homo sapiens_hsa050160.70072799
86Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69817239
87Olfactory transduction_Homo sapiens_hsa047400.69488851
88Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.69302219
89Pancreatic cancer_Homo sapiens_hsa052120.68350564
90Small cell lung cancer_Homo sapiens_hsa052220.67796799
91AMPK signaling pathway_Homo sapiens_hsa041520.67699520
92MAPK signaling pathway_Homo sapiens_hsa040100.67523233
93Thyroid cancer_Homo sapiens_hsa052160.66221150
94Renin secretion_Homo sapiens_hsa049240.65433255
95Phototransduction_Homo sapiens_hsa047440.65270681
96Dilated cardiomyopathy_Homo sapiens_hsa054140.64163428
97Bile secretion_Homo sapiens_hsa049760.64017593
98Tyrosine metabolism_Homo sapiens_hsa003500.63791657
99Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63326672
100Central carbon metabolism in cancer_Homo sapiens_hsa052300.63293525
101Insulin secretion_Homo sapiens_hsa049110.63191710
102Ovarian steroidogenesis_Homo sapiens_hsa049130.61343126
103Oxidative phosphorylation_Homo sapiens_hsa001900.59716495
104Parkinsons disease_Homo sapiens_hsa050120.59673828
105Oxytocin signaling pathway_Homo sapiens_hsa049210.58225895
106Prion diseases_Homo sapiens_hsa050200.56719275
107Protein export_Homo sapiens_hsa030600.55725803
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54843910
109Type II diabetes mellitus_Homo sapiens_hsa049300.54720414
110Ras signaling pathway_Homo sapiens_hsa040140.54039886
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.54009329
112Fanconi anemia pathway_Homo sapiens_hsa034600.53905291
113Fatty acid biosynthesis_Homo sapiens_hsa000610.53892392
114Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53517444
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.53475145
116Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.53446226
117Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52347292
118Folate biosynthesis_Homo sapiens_hsa007900.52174058
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.52058724
120Salivary secretion_Homo sapiens_hsa049700.51795440
121Fat digestion and absorption_Homo sapiens_hsa049750.49662931
122Phospholipase D signaling pathway_Homo sapiens_hsa040720.49218270
123Non-small cell lung cancer_Homo sapiens_hsa052230.48780123
124AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46981430
125Pyruvate metabolism_Homo sapiens_hsa006200.46690093
126Butanoate metabolism_Homo sapiens_hsa006500.46119310
127Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45216178
128Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44692279
129Calcium signaling pathway_Homo sapiens_hsa040200.44062629
130Thyroid hormone synthesis_Homo sapiens_hsa049180.43911747
131Amoebiasis_Homo sapiens_hsa051460.43374952
132Vascular smooth muscle contraction_Homo sapiens_hsa042700.43231255
133Circadian rhythm_Homo sapiens_hsa047100.41075477
134Steroid hormone biosynthesis_Homo sapiens_hsa001400.36274114

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