TMEM145

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of calcium ion-dependent exocytosis (GO:0045956)6.44720779
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.37079111
3synaptic vesicle maturation (GO:0016188)6.25475467
4locomotory exploration behavior (GO:0035641)5.85716319
5vocalization behavior (GO:0071625)5.50792122
6synaptic vesicle exocytosis (GO:0016079)5.45933563
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.39892439
8regulation of synaptic vesicle exocytosis (GO:2000300)5.35804533
9behavioral response to nicotine (GO:0035095)5.29304891
10glutamate secretion (GO:0014047)5.28947151
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.15276784
12cellular potassium ion homeostasis (GO:0030007)4.99893298
13protein localization to synapse (GO:0035418)4.92620686
14layer formation in cerebral cortex (GO:0021819)4.91735547
15synaptic vesicle docking involved in exocytosis (GO:0016081)4.84393882
16neurotransmitter secretion (GO:0007269)4.83925522
17sodium ion export (GO:0071436)4.79770168
18positive regulation of synapse maturation (GO:0090129)4.77272505
19cerebellar Purkinje cell differentiation (GO:0021702)4.73894126
20ionotropic glutamate receptor signaling pathway (GO:0035235)4.72342062
21cerebellar granule cell differentiation (GO:0021707)4.67248420
22regulation of synaptic vesicle transport (GO:1902803)4.65059728
23neuron cell-cell adhesion (GO:0007158)4.49652774
24gamma-aminobutyric acid transport (GO:0015812)4.49297826
25synaptic transmission, glutamatergic (GO:0035249)4.48417682
26exploration behavior (GO:0035640)4.47660267
27regulation of glutamate receptor signaling pathway (GO:1900449)4.46076655
28regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.44733203
29neuronal action potential propagation (GO:0019227)4.38506271
30axon ensheathment in central nervous system (GO:0032291)4.37858562
31central nervous system myelination (GO:0022010)4.37858562
32glutamate receptor signaling pathway (GO:0007215)4.37278247
33synaptic vesicle endocytosis (GO:0048488)4.10220672
34G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.06516912
35cell communication by electrical coupling (GO:0010644)4.00041476
36neuron-neuron synaptic transmission (GO:0007270)3.99525821
37cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.99264669
38dendritic spine morphogenesis (GO:0060997)3.97722682
39neurotransmitter-gated ion channel clustering (GO:0072578)3.95044219
40serotonin metabolic process (GO:0042428)3.91751308
41neuromuscular process controlling posture (GO:0050884)3.90866151
42regulation of neuronal synaptic plasticity (GO:0048168)3.90351894
43long-term memory (GO:0007616)3.88208848
44neuron recognition (GO:0008038)3.87213575
45neurotransmitter transport (GO:0006836)3.84475641
46axonal fasciculation (GO:0007413)3.83240212
47dendrite morphogenesis (GO:0048813)3.82985308
48regulation of synapse structural plasticity (GO:0051823)3.82647321
49cell differentiation in hindbrain (GO:0021533)3.82497668
50regulation of long-term neuronal synaptic plasticity (GO:0048169)3.77235126
51gamma-aminobutyric acid signaling pathway (GO:0007214)3.75363854
52primary amino compound metabolic process (GO:1901160)3.71459775
53regulation of synapse maturation (GO:0090128)3.67587275
54membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.64719269
55membrane hyperpolarization (GO:0060081)3.61477509
56regulation of neurotransmitter secretion (GO:0046928)3.61427876
57positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.60139859
58positive regulation of membrane potential (GO:0045838)3.59611780
59regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.59502257
60cell migration in hindbrain (GO:0021535)3.57906180
61proline transport (GO:0015824)3.55211171
62postsynaptic membrane organization (GO:0001941)3.52340472
63regulation of neurotransmitter levels (GO:0001505)3.52171770
64neuromuscular process controlling balance (GO:0050885)3.51169160
65regulation of postsynaptic membrane potential (GO:0060078)3.50602693
66negative regulation of microtubule polymerization (GO:0031115)3.50575345
67regulation of excitatory postsynaptic membrane potential (GO:0060079)3.50224846
68potassium ion homeostasis (GO:0055075)3.48273434
69presynaptic membrane assembly (GO:0097105)3.45772285
70auditory behavior (GO:0031223)3.43761674
71membrane depolarization during action potential (GO:0086010)3.43679640
72activation of protein kinase A activity (GO:0034199)3.42646597
73presynaptic membrane organization (GO:0097090)3.39148999
74synapse assembly (GO:0007416)3.35481381
75regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.34928817
76regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.34715615
77response to auditory stimulus (GO:0010996)3.33544456
78pyrimidine nucleobase catabolic process (GO:0006208)3.31571266
79transmission of nerve impulse (GO:0019226)3.29238928
80innervation (GO:0060384)3.27322422
81positive regulation of synaptic transmission, GABAergic (GO:0032230)3.26900939
82mating behavior (GO:0007617)3.24938771
83adult walking behavior (GO:0007628)3.24744720
84neuromuscular synaptic transmission (GO:0007274)3.23244010
85regulation of neurotransmitter transport (GO:0051588)3.22177581
86regulation of ARF protein signal transduction (GO:0032012)3.21017077
87glycine transport (GO:0015816)3.20791050
88regulation of calcium ion-dependent exocytosis (GO:0017158)3.18626522
89membrane depolarization (GO:0051899)3.18597211
90regulation of vesicle fusion (GO:0031338)3.18507523
91potassium ion import (GO:0010107)3.18411889
92establishment of nucleus localization (GO:0040023)3.14972445
93cerebellar Purkinje cell layer development (GO:0021680)3.14348696
94positive regulation of dendritic spine development (GO:0060999)3.10329518
95nucleobase catabolic process (GO:0046113)3.09678731
96cellular sodium ion homeostasis (GO:0006883)3.08472616
97regulation of synaptic transmission, glutamatergic (GO:0051966)3.08012864
98regulation of synaptic plasticity (GO:0048167)3.04303173
99positive regulation of potassium ion transmembrane transport (GO:1901381)3.03993531
100negative regulation of synaptic transmission, GABAergic (GO:0032229)3.03977726
101synapse organization (GO:0050808)3.03157460
102neuron remodeling (GO:0016322)3.02892341
103positive regulation of synapse assembly (GO:0051965)3.02810313
104axon cargo transport (GO:0008088)3.01809678
105mechanosensory behavior (GO:0007638)3.00326337
106positive regulation of dendritic spine morphogenesis (GO:0061003)3.00247300
107central nervous system projection neuron axonogenesis (GO:0021952)3.00107367
108regulation of respiratory system process (GO:0044065)2.97159326
109neuromuscular process (GO:0050905)2.97101503
110positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.96848536
111nephron epithelium morphogenesis (GO:0072088)2.94579393
112nephron tubule morphogenesis (GO:0072078)2.94579393
113startle response (GO:0001964)2.93927343
114intraspecies interaction between organisms (GO:0051703)2.93747296
115fucose catabolic process (GO:0019317)2.91982639
116L-fucose metabolic process (GO:0042354)2.91982639
117L-fucose catabolic process (GO:0042355)2.91982639
118neuronal action potential (GO:0019228)2.91038541
119indole-containing compound metabolic process (GO:0042430)2.90879743
120regulation of voltage-gated calcium channel activity (GO:1901385)2.89655397
121behavioral response to ethanol (GO:0048149)2.88791508
122negative regulation of cytosolic calcium ion concentration (GO:0051481)2.81973470
123regulation of neurotransmitter uptake (GO:0051580)2.81109070
124detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.75385528
125adult behavior (GO:0030534)2.72389707
126protein polyglutamylation (GO:0018095)2.70329409
127mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.69766082
128mitochondrial respiratory chain complex I assembly (GO:0032981)2.69766082
129NADH dehydrogenase complex assembly (GO:0010257)2.69766082
130spinal cord motor neuron differentiation (GO:0021522)2.69258139
131positive regulation of oligodendrocyte differentiation (GO:0048714)2.63816107
132synaptic transmission (GO:0007268)2.63595731
133calcium ion-dependent exocytosis (GO:0017156)2.62235768
134potassium ion transmembrane transport (GO:0071805)2.58542899
135cellular potassium ion transport (GO:0071804)2.58542899
136cAMP catabolic process (GO:0006198)2.57824486
137action potential (GO:0001508)2.57742165
138neuron maturation (GO:0042551)2.57367065
139negative regulation of telomere maintenance (GO:0032205)2.56913069

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.78850410
2GBX2_23144817_ChIP-Seq_PC3_Human3.10512051
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.08466907
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.04120627
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.01390595
6* REST_21632747_ChIP-Seq_MESCs_Mouse2.97949343
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82800463
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82800463
9DROSHA_22980978_ChIP-Seq_HELA_Human2.77232671
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74063546
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.66520925
12CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.64494201
13EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.62280547
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.61566037
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.59296308
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.58943988
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.54918259
18REST_18959480_ChIP-ChIP_MESCs_Mouse2.52850000
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.48749232
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.47468409
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.46932433
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.41092363
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.40867062
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40425247
25RARB_27405468_Chip-Seq_BRAIN_Mouse2.38383863
26EED_16625203_ChIP-ChIP_MESCs_Mouse2.37888587
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.34661537
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.23444319
29VDR_22108803_ChIP-Seq_LS180_Human2.11482278
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.09366285
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.06177500
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81666525
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.77437546
34AR_21572438_ChIP-Seq_LNCaP_Human1.73672739
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65629355
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53483113
37RING1B_27294783_Chip-Seq_ESCs_Mouse1.51099944
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50315242
39DNAJC2_21179169_ChIP-ChIP_NT2_Human1.49270555
40ZFP281_18757296_ChIP-ChIP_E14_Mouse1.47919506
41* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.47627337
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.45085625
43HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.44490337
44KDM2B_26808549_Chip-Seq_K562_Human1.44422057
45RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37173448
46MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36028996
47SMAD4_21799915_ChIP-Seq_A2780_Human1.35530058
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34749194
49EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32645025
50CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.32424846
51RING1B_27294783_Chip-Seq_NPCs_Mouse1.31752616
52EWS_26573619_Chip-Seq_HEK293_Human1.31154099
53RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30893407
54FUS_26573619_Chip-Seq_HEK293_Human1.30504859
55PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.30318619
56ETV2_25802403_ChIP-Seq_MESCs_Mouse1.29665620
57RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.27982825
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.27485994
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27113026
60AR_19668381_ChIP-Seq_PC3_Human1.26649033
61CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26424512
62* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.26320101
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.22716913
64* ZNF274_21170338_ChIP-Seq_K562_Hela1.21737707
65ER_23166858_ChIP-Seq_MCF-7_Human1.18008412
66WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.17866724
67P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17411507
68FLI1_27457419_Chip-Seq_LIVER_Mouse1.17135406
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.16917381
70MYC_18940864_ChIP-ChIP_HL60_Human1.16728316
71TP53_22573176_ChIP-Seq_HFKS_Human1.15935636
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15372538
73OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.15281118
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14659787
75RNF2_27304074_Chip-Seq_NSC_Mouse1.13896190
76IRF1_19129219_ChIP-ChIP_H3396_Human1.12696827
77TAF15_26573619_Chip-Seq_HEK293_Human1.11778924
78NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11705784
79WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11180038
80GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09683593
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08310712
82IGF1R_20145208_ChIP-Seq_DFB_Human1.07973423
83ZFP281_27345836_Chip-Seq_ESCs_Mouse1.06703823
84TET1_21490601_ChIP-Seq_MESCs_Mouse1.06309349
85BCAT_22108803_ChIP-Seq_LS180_Human1.06112323
86AR_25329375_ChIP-Seq_VCAP_Human1.05998489
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05782054
88SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.04649268
89NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03940080
90TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.02571524
91CBP_20019798_ChIP-Seq_JUKART_Human1.01894033
92IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01894033
93STAT3_23295773_ChIP-Seq_U87_Human1.01277668
94SMAD3_21741376_ChIP-Seq_ESCs_Human1.01096930
95PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00478570
96TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.00291863
97FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00076775
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99901575
99YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99871791
100NCOR_22424771_ChIP-Seq_293T_Human0.98698645
101ZFP57_27257070_Chip-Seq_ESCs_Mouse0.98039791
102ERA_21632823_ChIP-Seq_H3396_Human0.97326379
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96991919
104TAF2_19829295_ChIP-Seq_ESCs_Human0.96976972
105CTCF_27219007_Chip-Seq_Bcells_Human0.96227766
106TP53_20018659_ChIP-ChIP_R1E_Mouse0.95608604
107* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.95377914
108P300_19829295_ChIP-Seq_ESCs_Human0.95124001
109GATA3_21878914_ChIP-Seq_MCF-7_Human0.94942612
110SMAD3_21741376_ChIP-Seq_EPCs_Human0.94441303
111CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94107000
112MYC_19829295_ChIP-Seq_ESCs_Human0.93297162
113MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92715658
114SMAD4_21741376_ChIP-Seq_HESCs_Human0.92509779
115PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91826926
116SOX2_19829295_ChIP-Seq_ESCs_Human0.91486453
117NANOG_19829295_ChIP-Seq_ESCs_Human0.91486453
118AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91410591
119DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.89481520
120TOP2B_26459242_ChIP-Seq_MCF-7_Human0.89176334
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89074434
122TCF4_23295773_ChIP-Seq_U87_Human0.88352910
123ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.87954044
124THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87587716
125ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.85355220
126ARNT_22903824_ChIP-Seq_MCF-7_Human0.85064718
127OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84688235
128TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81396640
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.81396640
130AHR_22903824_ChIP-Seq_MCF-7_Human0.81279614
131KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80966817
132EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.80297539
133* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.80224426
134TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78247906
135ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77540062
136RUNX2_22187159_ChIP-Seq_PCA_Human0.77215512
137SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.76914163
138SMAD_19615063_ChIP-ChIP_OVARY_Human0.76856371

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.90806442
2MP0003880_abnormal_central_pattern4.33738253
3MP0003635_abnormal_synaptic_transmissio3.97387247
4MP0005423_abnormal_somatic_nervous3.95127342
5MP0009046_muscle_twitch3.54710658
6MP0004270_analgesia3.30504326
7MP0002063_abnormal_learning/memory/cond3.06615467
8MP0002064_seizures2.95625093
9MP0009745_abnormal_behavioral_response2.92894897
10MP0001968_abnormal_touch/_nociception2.72703713
11MP0002734_abnormal_mechanical_nocicepti2.67752168
12MP0002272_abnormal_nervous_system2.55454457
13MP0002572_abnormal_emotion/affect_behav2.52543688
14MP0001486_abnormal_startle_reflex2.37638595
15MP0003136_yellow_coat_color2.34914437
16MP0008569_lethality_at_weaning2.33070528
17MP0002184_abnormal_innervation2.30810128
18MP0002735_abnormal_chemical_nociception2.29175569
19MP0000778_abnormal_nervous_system2.25809695
20MP0001440_abnormal_grooming_behavior2.18344320
21MP0002067_abnormal_sensory_capabilities2.14009180
22MP0002733_abnormal_thermal_nociception2.11597318
23MP0002736_abnormal_nociception_after2.02193528
24MP0006276_abnormal_autonomic_nervous2.01548595
25MP0001501_abnormal_sleep_pattern1.94956321
26MP0001970_abnormal_pain_threshold1.94068618
27MP0001984_abnormal_olfaction1.93742292
28MP0005645_abnormal_hypothalamus_physiol1.91737354
29MP0002557_abnormal_social/conspecific_i1.88141736
30MP0003122_maternal_imprinting1.87160661
31MP0004811_abnormal_neuron_physiology1.86765694
32MP0000955_abnormal_spinal_cord1.84794903
33MP0003329_amyloid_beta_deposits1.84739779
34MP0004145_abnormal_muscle_electrophysio1.73847996
35MP0001502_abnormal_circadian_rhythm1.72795728
36MP0004858_abnormal_nervous_system1.71449465
37MP0005551_abnormal_eye_electrophysiolog1.70470303
38MP0005386_behavior/neurological_phenoty1.65911523
39MP0004924_abnormal_behavior1.65911523
40MP0002909_abnormal_adrenal_gland1.63466205
41MP0002882_abnormal_neuron_morphology1.62199753
42MP0004885_abnormal_endolymph1.61906453
43MP0008877_abnormal_DNA_methylation1.59657948
44MP0002102_abnormal_ear_morphology1.56961913
45MP0001485_abnormal_pinna_reflex1.55012457
46MP0009780_abnormal_chondrocyte_physiolo1.52165029
47MP0002066_abnormal_motor_capabilities/c1.48580766
48MP0001986_abnormal_taste_sensitivity1.45954379
49MP0004142_abnormal_muscle_tone1.45585003
50MP0003879_abnormal_hair_cell1.43478775
51MP0004133_heterotaxia1.41083168
52MP0001905_abnormal_dopamine_level1.38210509
53MP0004043_abnormal_pH_regulation1.32980076
54MP0006292_abnormal_olfactory_placode1.32501431
55MP0004147_increased_porphyrin_level1.31721899
56MP0002152_abnormal_brain_morphology1.30510785
57MP0006072_abnormal_retinal_apoptosis1.28221676
58MP0005646_abnormal_pituitary_gland1.23169408
59MP0000569_abnormal_digit_pigmentation1.21743167
60MP0003633_abnormal_nervous_system1.20368433
61MP0002638_abnormal_pupillary_reflex1.18944985
62MP0008961_abnormal_basal_metabolism1.15717204
63MP0004742_abnormal_vestibular_system1.15178960
64MP0002938_white_spotting1.14957865
65MP0002229_neurodegeneration1.14225166
66MP0005394_taste/olfaction_phenotype1.11381791
67MP0005499_abnormal_olfactory_system1.11381791
68MP0003787_abnormal_imprinting1.10863496
69MP0002837_dystrophic_cardiac_calcinosis1.09309264
70MP0003631_nervous_system_phenotype1.09019668
71MP0005253_abnormal_eye_physiology1.05751684
72MP0003195_calcinosis1.05415125
73MP0003283_abnormal_digestive_organ1.04636322
74MP0002752_abnormal_somatic_nervous1.03969381
75MP0008875_abnormal_xenobiotic_pharmacok1.03938880
76MP0003632_abnormal_nervous_system1.01609670
77MP0000631_abnormal_neuroendocrine_gland1.01081011
78MP0003646_muscle_fatigue1.01013892
79MP0009379_abnormal_foot_pigmentation1.00931581
80MP0000026_abnormal_inner_ear1.00631789
81MP0002069_abnormal_eating/drinking_beha0.98998712
82MP0002653_abnormal_ependyma_morphology0.98026181
83MP0002876_abnormal_thyroid_physiology0.96257256
84MP0003634_abnormal_glial_cell0.93221923
85MP0000751_myopathy0.91868719
86MP0004233_abnormal_muscle_weight0.89840545
87MP0003137_abnormal_impulse_conducting0.89159521
88MP0005187_abnormal_penis_morphology0.87333466
89MP0010386_abnormal_urinary_bladder0.85801263
90MP0003119_abnormal_digestive_system0.85409334
91MP0003861_abnormal_nervous_system0.84609558
92MP0003121_genomic_imprinting0.83519433
93MP0002090_abnormal_vision0.83497974
94MP0008872_abnormal_physiological_respon0.82339934
95MP0003011_delayed_dark_adaptation0.81943063
96MP0002160_abnormal_reproductive_system0.81208065
97MP0002089_abnormal_postnatal_growth/wei0.80674011
98MP0002163_abnormal_gland_morphology0.78082647
99MP0001963_abnormal_hearing_physiology0.78022916
100MP0004215_abnormal_myocardial_fiber0.75553967
101MP0000013_abnormal_adipose_tissue0.74381019
102MP0002822_catalepsy0.74361665
103MP0000604_amyloidosis0.72916034
104MP0002928_abnormal_bile_duct0.72486119
105MP0001299_abnormal_eye_distance/0.72197209
106MP0003123_paternal_imprinting0.71814221
107MP0004085_abnormal_heartbeat0.71776113
108MP0001529_abnormal_vocalization0.71427006
109MP0005167_abnormal_blood-brain_barrier0.70616935
110MP0005410_abnormal_fertilization0.69981045
111MP0005379_endocrine/exocrine_gland_phen0.69543957
112MP0008995_early_reproductive_senescence0.68882159
113MP0000427_abnormal_hair_cycle0.68768147
114MP0004130_abnormal_muscle_cell0.67929572
115MP0005448_abnormal_energy_balance0.67458692
116MP0003698_abnormal_male_reproductive0.67352345
117MP0003172_abnormal_lysosome_physiology0.66960546
118MP0010769_abnormal_survival0.66938533
119MP0001177_atelectasis0.65105821
120MP0010770_preweaning_lethality0.64769857
121MP0002082_postnatal_lethality0.64769857
122MP0003690_abnormal_glial_cell0.63875857
123MP0010768_mortality/aging0.63707423
124MP0002234_abnormal_pharynx_morphology0.62103697
125MP0005623_abnormal_meninges_morphology0.61281550
126MP0005195_abnormal_posterior_eye0.60514923
127MP0000534_abnormal_ureter_morphology0.60165167
128MP0001188_hyperpigmentation0.59855345
129MP0005535_abnormal_body_temperature0.59305266
130MP0001943_abnormal_respiration0.59204802
131MP0000920_abnormal_myelination0.58919127

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.64531608
2Myokymia (HP:0002411)5.48510714
3Visual hallucinations (HP:0002367)5.38005023
4Progressive cerebellar ataxia (HP:0002073)5.23735337
5Focal seizures (HP:0007359)5.09046181
6Action tremor (HP:0002345)4.53510843
7Epileptic encephalopathy (HP:0200134)4.51778745
8Supranuclear gaze palsy (HP:0000605)4.01618264
9Febrile seizures (HP:0002373)4.01123966
10Atonic seizures (HP:0010819)3.87123559
11Absence seizures (HP:0002121)3.74594500
12Mutism (HP:0002300)3.66112507
13Genetic anticipation (HP:0003743)3.54372278
14Abnormal eating behavior (HP:0100738)3.53753112
15Hemiparesis (HP:0001269)3.53163979
16Ankle clonus (HP:0011448)3.48515387
17True hermaphroditism (HP:0010459)3.43886873
18Broad-based gait (HP:0002136)3.41161534
19Molar tooth sign on MRI (HP:0002419)3.41068188
20Abnormality of midbrain morphology (HP:0002418)3.41068188
21Gaze-evoked nystagmus (HP:0000640)3.40112520
22Dialeptic seizures (HP:0011146)3.30300174
23Dysdiadochokinesis (HP:0002075)3.30065511
24Hemiplegia (HP:0002301)3.29666341
25Polyphagia (HP:0002591)3.29398877
26Generalized tonic-clonic seizures (HP:0002069)3.22675704
27Abnormality of the lower motor neuron (HP:0002366)3.22428508
28Pancreatic cysts (HP:0001737)3.21534387
29Poor eye contact (HP:0000817)3.18455625
30Depression (HP:0000716)3.17507251
31Agitation (HP:0000713)3.09631094
32Truncal ataxia (HP:0002078)3.07850356
33Pancreatic fibrosis (HP:0100732)3.06288723
34Impaired smooth pursuit (HP:0007772)3.05800889
35Nephronophthisis (HP:0000090)2.94433115
36Abnormality of binocular vision (HP:0011514)2.89019538
37Diplopia (HP:0000651)2.89019538
38Impaired social interactions (HP:0000735)2.88797262
39Abnormal social behavior (HP:0012433)2.88797262
40Dysmetria (HP:0001310)2.87300220
41Abnormality of ocular smooth pursuit (HP:0000617)2.86579980
42Failure to thrive in infancy (HP:0001531)2.80413207
43Scanning speech (HP:0002168)2.78826696
44Excessive salivation (HP:0003781)2.77734093
45Drooling (HP:0002307)2.77734093
46Abnormality of alanine metabolism (HP:0010916)2.73308598
47Hyperalaninemia (HP:0003348)2.73308598
48Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.73308598
49Postural instability (HP:0002172)2.72809115
50Intention tremor (HP:0002080)2.71205136
51Amyotrophic lateral sclerosis (HP:0007354)2.70981277
52Type II lissencephaly (HP:0007260)2.69903066
53Central scotoma (HP:0000603)2.66106097
54Anxiety (HP:0000739)2.62022528
55Spastic gait (HP:0002064)2.61349175
56Ventricular fibrillation (HP:0001663)2.59581359
57Dysmetric saccades (HP:0000641)2.59131479
58Congenital stationary night blindness (HP:0007642)2.58578899
59Urinary bladder sphincter dysfunction (HP:0002839)2.58143077
60Insomnia (HP:0100785)2.51143003
61Abnormality of the renal medulla (HP:0100957)2.51010192
62Pendular nystagmus (HP:0012043)2.50834340
63Impaired vibration sensation in the lower limbs (HP:0002166)2.49679990
64Status epilepticus (HP:0002133)2.43455549
65Inability to walk (HP:0002540)2.43352656
66Abnormality of the corticospinal tract (HP:0002492)2.42160227
67Amblyopia (HP:0000646)2.38257606
68Papilledema (HP:0001085)2.36477214
69Neoplasm of the heart (HP:0100544)2.35160660
70Polydipsia (HP:0001959)2.33894098
71Abnormal drinking behavior (HP:0030082)2.33894098
72Cystic liver disease (HP:0006706)2.33786728
73EEG with generalized epileptiform discharges (HP:0011198)2.33527018
74Epileptiform EEG discharges (HP:0011182)2.30857670
75Gait imbalance (HP:0002141)2.30241031
76Abnormality of macular pigmentation (HP:0008002)2.24234842
77Limb dystonia (HP:0002451)2.23964520
78Bradykinesia (HP:0002067)2.23391919
79Medial flaring of the eyebrow (HP:0010747)2.22955545
80Sclerocornea (HP:0000647)2.22596978
81Tetraplegia (HP:0002445)2.22334275
82Attenuation of retinal blood vessels (HP:0007843)2.20843247
83Neuroendocrine neoplasm (HP:0100634)2.20432761
84Dynein arm defect of respiratory motile cilia (HP:0012255)2.19090502
85Absent/shortened dynein arms (HP:0200106)2.19090502
86Urinary urgency (HP:0000012)2.18456712
87Neurofibrillary tangles (HP:0002185)2.18292482
88Optic nerve hypoplasia (HP:0000609)2.18086020
89Morphological abnormality of the pyramidal tract (HP:0002062)2.17806110
90Abolished electroretinogram (ERG) (HP:0000550)2.17369374
91Torticollis (HP:0000473)2.16672545
92Stereotypic behavior (HP:0000733)2.16615282
93Hypsarrhythmia (HP:0002521)2.15811149
94Progressive inability to walk (HP:0002505)2.15757096
95Fetal akinesia sequence (HP:0001989)2.10255702
96Pointed chin (HP:0000307)2.10187480
97Abnormality of the renal cortex (HP:0011035)2.10175743
98Large for gestational age (HP:0001520)2.09261191
99Sleep apnea (HP:0010535)2.09011643
100Hypoventilation (HP:0002791)2.07844040
101Clonus (HP:0002169)2.07721864
102Specific learning disability (HP:0001328)2.07230034
103Pheochromocytoma (HP:0002666)2.04293697
104Megalencephaly (HP:0001355)2.04266463
105Lissencephaly (HP:0001339)2.03609913
106Decreased central vision (HP:0007663)2.02045918
107Polyuria (HP:0000103)2.01257627
108Focal dystonia (HP:0004373)2.00964234
109Lower limb muscle weakness (HP:0007340)2.00561718
110Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.99644760
111Tubular atrophy (HP:0000092)1.99319639
112Chronic hepatic failure (HP:0100626)1.98496950
113Acute necrotizing encephalopathy (HP:0006965)1.96818544
114Hyperventilation (HP:0002883)1.96381890
115Abnormality of saccadic eye movements (HP:0000570)1.95832871
116Retinal dysplasia (HP:0007973)1.95439354
117Neuronal loss in central nervous system (HP:0002529)1.95374729
118Limb ataxia (HP:0002070)1.95137073
119Cerebral inclusion bodies (HP:0100314)1.93993448
120Esotropia (HP:0000565)1.93959062
121Gait ataxia (HP:0002066)1.92967971
122Partial agenesis of the corpus callosum (HP:0001338)1.89868456
123Absent speech (HP:0001344)1.89614572
124Horizontal nystagmus (HP:0000666)1.89502367
125Furrowed tongue (HP:0000221)1.89030838
126Patellar aplasia (HP:0006443)1.88580598
127Aplasia/Hypoplasia of the tibia (HP:0005772)1.88578307
128Hyperacusis (HP:0010780)1.87812839
129Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.87625538
130Akinesia (HP:0002304)1.87285633
131Aplasia/Hypoplasia of the brainstem (HP:0007362)1.86431559
132Hypoplasia of the brainstem (HP:0002365)1.86431559
133Birth length less than 3rd percentile (HP:0003561)1.85315839
134Concave nail (HP:0001598)1.85026784
135Aplasia/Hypoplasia of the patella (HP:0006498)1.84790817
136Postural tremor (HP:0002174)1.84622928
137Congenital primary aphakia (HP:0007707)1.84324772
138Cerebral hypomyelination (HP:0006808)1.83939614
139Spastic tetraplegia (HP:0002510)1.83398683
140Mitochondrial inheritance (HP:0001427)1.81956155
141Psychosis (HP:0000709)1.81915209
142Severe muscular hypotonia (HP:0006829)1.80729838
143Abnormal EKG (HP:0003115)1.78646585
144Anencephaly (HP:0002323)1.78567283
145Optic disc pallor (HP:0000543)1.78499474
146Abnormality of the diencephalon (HP:0010662)1.78476901
147Confusion (HP:0001289)1.78165462
148Apathy (HP:0000741)1.77226320
149Craniofacial dystonia (HP:0012179)1.76864801
150Septo-optic dysplasia (HP:0100842)1.76336560
151Progressive macrocephaly (HP:0004481)1.76241982
152Elfin facies (HP:0004428)1.76204744
153Incomplete penetrance (HP:0003829)1.75874099
154Cerebellar dysplasia (HP:0007033)1.75323070
155Metabolic alkalosis (HP:0200114)1.74745164
156Abnormal respiratory epithelium morphology (HP:0012253)1.73140678
157Abnormal respiratory motile cilium morphology (HP:0005938)1.73140678
158Dyskinesia (HP:0100660)1.71877351
159Nephrogenic diabetes insipidus (HP:0009806)1.69090209
160Abnormal rod and cone electroretinograms (HP:0008323)1.68002837
161Keratoconus (HP:0000563)1.66239147
162Increased corneal curvature (HP:0100692)1.66239147

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.92862417
2MAP3K93.89590860
3NTRK33.40483012
4BMPR1B2.99010794
5MINK12.97394432
6MAP3K42.93207994
7PAK62.84602619
8NTRK22.74260204
9WNK42.69377640
10ADRBK22.67625473
11ACVR1B2.54809501
12FRK2.32154091
13DAPK22.31974616
14MAP2K72.23562239
15CAMKK11.99030061
16WNK31.97336135
17CAMKK21.84017220
18MAP2K41.82364148
19TLK11.79449644
20PHKG21.75306596
21PHKG11.75306596
22RIPK11.75248968
23KSR11.74642028
24STK381.73184423
25MAP4K21.71884926
26GRK11.68261764
27EPHA41.63088941
28MAPK131.58847641
29UHMK11.57690146
30SIK21.55286838
31CDK191.54769674
32ZAK1.54410003
33CDK51.52918237
34INSRR1.50636039
35PRKD31.48067084
36KSR21.38323706
37MAP3K121.37166336
38GRK51.25869716
39TYRO31.24698165
40NTRK11.23143956
41MAPK151.22489922
42PRKCG1.20855688
43PNCK1.17833747
44TNIK1.17808815
45CASK1.16671919
46TGFBR11.13944393
47CDK181.13175759
48ADRBK11.11895089
49STK391.10674940
50CDK151.10522730
51LATS21.09729251
52NEK11.08450426
53DYRK1A1.08432818
54PRPF4B1.07447407
55DAPK11.06486223
56CDK141.03280465
57PLK20.99100667
58ERBB30.98917595
59ALK0.98283429
60STK110.97630160
61CDK11A0.97371546
62SGK2230.95834404
63SGK4940.95834404
64EPHB20.95063265
65CAMK10.93802114
66SIK30.92103987
67WNK10.91635562
68WEE10.90501677
69MARK20.90288973
70LMTK20.89930694
71MAP2K60.89722734
72CAMK1G0.87863621
73TAOK10.86958748
74MAPKAPK50.85207758
75ICK0.84742034
76PAK30.82509600
77RET0.81697242
78DYRK20.79487094
79PRKCH0.77743685
80PINK10.77427997
81CSNK1G20.75935815
82MAP2K20.73244907
83CDC42BPA0.73120430
84CAMK2A0.72111302
85FES0.67505849
86PRKCZ0.64982711
87SGK20.63982897
88TRIM280.63490155
89CAMK1D0.63337383
90RPS6KA50.62774748
91OXSR10.60756823
92SGK10.60495284
93SGK30.59944904
94MAP2K10.59259495
95ERBB20.58575922
96CAMK40.57289586
97NEK20.55687246
98BCR0.55409208
99RPS6KA30.53399097
100CAMK2B0.52790886
101PRKACA0.51763059
102MAP3K20.51297672
103RPS6KA20.51069063
104BRSK10.50816180
105NUAK10.50049833
106FYN0.49486392
107PIK3CA0.48644494
108PKN10.48498424
109TAOK30.48447472
110BCKDK0.48258308
111SCYL20.47441705
112MAPK100.47080139
113PRKCA0.46952905
114PRKCI0.46434677
115RIPK40.46228026
116FER0.45682597
117VRK10.44457182
118PRKCQ0.44431398
119PRKAA10.43787682
120MAPK90.43261240
121CAMK2G0.40752979
122ROCK20.39892107
123CAMK2D0.39126033
124TXK0.38719652
125TIE10.38320057
126NME10.36960748
127MAPK80.36725282
128RPS6KA60.36199393
129FGFR20.36068025
130PRKG10.35829139
131IRAK20.35454765
132MAPK120.34302678
133CSNK1G30.34232051
134LIMK10.33931986
135PRKCE0.33064376
136PRKCB0.32610165

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.29735739
2Synaptic vesicle cycle_Homo sapiens_hsa047213.63725043
3GABAergic synapse_Homo sapiens_hsa047272.94187475
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76803245
5Glutamatergic synapse_Homo sapiens_hsa047242.72298878
6Circadian entrainment_Homo sapiens_hsa047132.70856331
7Morphine addiction_Homo sapiens_hsa050322.46540498
8Oxidative phosphorylation_Homo sapiens_hsa001902.40227125
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.37822234
10Long-term potentiation_Homo sapiens_hsa047202.37754709
11Olfactory transduction_Homo sapiens_hsa047402.16792218
12Insulin secretion_Homo sapiens_hsa049112.09277966
13Salivary secretion_Homo sapiens_hsa049702.06856168
14Dopaminergic synapse_Homo sapiens_hsa047281.99467971
15Amphetamine addiction_Homo sapiens_hsa050311.98966814
16Taste transduction_Homo sapiens_hsa047421.93538523
17Parkinsons disease_Homo sapiens_hsa050121.88452136
18Cholinergic synapse_Homo sapiens_hsa047251.84826125
19Long-term depression_Homo sapiens_hsa047301.83110680
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.79245222
21Gastric acid secretion_Homo sapiens_hsa049711.73578719
22Linoleic acid metabolism_Homo sapiens_hsa005911.73108389
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.72525593
24Butanoate metabolism_Homo sapiens_hsa006501.69331906
25alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.69023389
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.66320442
27Oxytocin signaling pathway_Homo sapiens_hsa049211.57192088
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55265590
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.52509335
30Type II diabetes mellitus_Homo sapiens_hsa049301.45723752
31Serotonergic synapse_Homo sapiens_hsa047261.44093252
32Alzheimers disease_Homo sapiens_hsa050101.43481589
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.43335271
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41572755
35Cocaine addiction_Homo sapiens_hsa050301.40104530
36Renin secretion_Homo sapiens_hsa049241.39333778
37Ether lipid metabolism_Homo sapiens_hsa005651.38717455
38Axon guidance_Homo sapiens_hsa043601.38531212
39Gap junction_Homo sapiens_hsa045401.37322243
40Calcium signaling pathway_Homo sapiens_hsa040201.33823502
41GnRH signaling pathway_Homo sapiens_hsa049121.30346209
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.28668358
43Phototransduction_Homo sapiens_hsa047441.27253903
44Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.22879452
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17513514
46cAMP signaling pathway_Homo sapiens_hsa040241.15792382
47Collecting duct acid secretion_Homo sapiens_hsa049661.15217014
48Estrogen signaling pathway_Homo sapiens_hsa049151.10947968
49Cardiac muscle contraction_Homo sapiens_hsa042601.10276250
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.10048571
51Huntingtons disease_Homo sapiens_hsa050161.09372860
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.03974803
53Tryptophan metabolism_Homo sapiens_hsa003801.03867151
54Selenocompound metabolism_Homo sapiens_hsa004501.01277403
55cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95347717
56RNA polymerase_Homo sapiens_hsa030200.92535888
57Oocyte meiosis_Homo sapiens_hsa041140.92323096
58Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91558991
59Pancreatic secretion_Homo sapiens_hsa049720.90382249
60Melanogenesis_Homo sapiens_hsa049160.90297841
61ErbB signaling pathway_Homo sapiens_hsa040120.89795248
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.89356347
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.89255707
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.86159247
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.85250636
66Dilated cardiomyopathy_Homo sapiens_hsa054140.84960915
67Circadian rhythm_Homo sapiens_hsa047100.83337891
68Glioma_Homo sapiens_hsa052140.81377803
69Thyroid hormone synthesis_Homo sapiens_hsa049180.81168927
70Fanconi anemia pathway_Homo sapiens_hsa034600.79524787
71Protein export_Homo sapiens_hsa030600.79517927
72Histidine metabolism_Homo sapiens_hsa003400.79350967
73Vibrio cholerae infection_Homo sapiens_hsa051100.76506894
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.75885412
75Homologous recombination_Homo sapiens_hsa034400.74873436
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74607210
77mTOR signaling pathway_Homo sapiens_hsa041500.74184563
78Regulation of autophagy_Homo sapiens_hsa041400.73371698
79MAPK signaling pathway_Homo sapiens_hsa040100.72490585
80Choline metabolism in cancer_Homo sapiens_hsa052310.71660923
81Vascular smooth muscle contraction_Homo sapiens_hsa042700.71074538
82Dorso-ventral axis formation_Homo sapiens_hsa043200.69247262
83Cyanoamino acid metabolism_Homo sapiens_hsa004600.68955106
84Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68298716
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.67829518
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.67031732
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66888089
88Bile secretion_Homo sapiens_hsa049760.65811392
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.65525083
90beta-Alanine metabolism_Homo sapiens_hsa004100.63792988
91Sulfur relay system_Homo sapiens_hsa041220.63408206
92Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63286585
93Nitrogen metabolism_Homo sapiens_hsa009100.63037748
94Inositol phosphate metabolism_Homo sapiens_hsa005620.61594951
95Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61174253
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60430979
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60239125
98Basal transcription factors_Homo sapiens_hsa030220.60068764
99Endometrial cancer_Homo sapiens_hsa052130.59835045
100Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59332800
101Endocytosis_Homo sapiens_hsa041440.55753388
102Ribosome_Homo sapiens_hsa030100.55386181
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54718136
104Caffeine metabolism_Homo sapiens_hsa002320.53672951
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52510148
106Alcoholism_Homo sapiens_hsa050340.51970700
107Peroxisome_Homo sapiens_hsa041460.50013547
108ABC transporters_Homo sapiens_hsa020100.48932701
109VEGF signaling pathway_Homo sapiens_hsa043700.48466121
110Glucagon signaling pathway_Homo sapiens_hsa049220.48433398
111RNA degradation_Homo sapiens_hsa030180.46881228
112Renal cell carcinoma_Homo sapiens_hsa052110.45950624
113Propanoate metabolism_Homo sapiens_hsa006400.45147247
114Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44602384
115Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43872179
116Colorectal cancer_Homo sapiens_hsa052100.43767109
117Mineral absorption_Homo sapiens_hsa049780.43708764
118Insulin signaling pathway_Homo sapiens_hsa049100.42886295
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.42680115
120Wnt signaling pathway_Homo sapiens_hsa043100.41898803
121Primary bile acid biosynthesis_Homo sapiens_hsa001200.41766797
122Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.41363936
123Ras signaling pathway_Homo sapiens_hsa040140.41005025
124Arachidonic acid metabolism_Homo sapiens_hsa005900.40773647
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40008320
126Arginine and proline metabolism_Homo sapiens_hsa003300.39727872
127Rap1 signaling pathway_Homo sapiens_hsa040150.37188978
128Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36302711
129Central carbon metabolism in cancer_Homo sapiens_hsa052300.35885836
130Basal cell carcinoma_Homo sapiens_hsa052170.35801776
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35587879
132Steroid hormone biosynthesis_Homo sapiens_hsa001400.35162555
133Ovarian steroidogenesis_Homo sapiens_hsa049130.35109371
134Hedgehog signaling pathway_Homo sapiens_hsa043400.34479799
135Fatty acid biosynthesis_Homo sapiens_hsa000610.34178538
136Purine metabolism_Homo sapiens_hsa002300.34046326
137Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32917963
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32010795
139Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31003423
140Glycerophospholipid metabolism_Homo sapiens_hsa005640.30877410
141AMPK signaling pathway_Homo sapiens_hsa041520.30300678
142Prion diseases_Homo sapiens_hsa050200.26800059
143Non-small cell lung cancer_Homo sapiens_hsa052230.26621142

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