TMEM150C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular visceral epithelial cell development (GO:0072015)6.10990810
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.69430543
3synaptic vesicle maturation (GO:0016188)5.48253170
4glomerular epithelial cell development (GO:0072310)5.41061803
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.37313797
6locomotory exploration behavior (GO:0035641)4.75116936
7synaptic vesicle exocytosis (GO:0016079)4.74775892
8glutamate secretion (GO:0014047)4.63989718
9cellular ketone body metabolic process (GO:0046950)4.62331732
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.60377560
11regulation of synaptic vesicle exocytosis (GO:2000300)4.49043501
12vocalization behavior (GO:0071625)4.46864707
13protein localization to synapse (GO:0035418)4.37776628
14synaptic vesicle docking involved in exocytosis (GO:0016081)4.34716531
15regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.32302407
16glomerular basement membrane development (GO:0032836)4.17207125
17ketone body metabolic process (GO:1902224)4.17065174
18regulation of glutamate receptor signaling pathway (GO:1900449)4.11676295
19regulation of synaptic vesicle transport (GO:1902803)4.09704625
20neuron cell-cell adhesion (GO:0007158)4.01028566
21exploration behavior (GO:0035640)3.94992854
22ionotropic glutamate receptor signaling pathway (GO:0035235)3.86915308
23regulation of neuronal synaptic plasticity (GO:0048168)3.76299783
24neuron recognition (GO:0008038)3.74258320
25synaptic transmission, glutamatergic (GO:0035249)3.69754778
26neurotransmitter secretion (GO:0007269)3.69527432
27cellular potassium ion homeostasis (GO:0030007)3.69145026
28proline transport (GO:0015824)3.68738881
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.64490016
30layer formation in cerebral cortex (GO:0021819)3.59357200
31activation of protein kinase A activity (GO:0034199)3.58960381
32regulation of long-term neuronal synaptic plasticity (GO:0048169)3.57929649
33long-term memory (GO:0007616)3.53669086
34neuronal action potential propagation (GO:0019227)3.49741554
35glutamate receptor signaling pathway (GO:0007215)3.48315857
36regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.48177270
37positive regulation of synaptic transmission, GABAergic (GO:0032230)3.46913157
38neuron-neuron synaptic transmission (GO:0007270)3.46866485
39regulation of synapse structural plasticity (GO:0051823)3.42586862
40sodium ion export (GO:0071436)3.40447382
41axonal fasciculation (GO:0007413)3.37588798
42cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.35284955
43regulation of vesicle fusion (GO:0031338)3.31134648
44innervation (GO:0060384)3.31077534
45neurotransmitter-gated ion channel clustering (GO:0072578)3.22342780
46synaptic vesicle endocytosis (GO:0048488)3.21610358
47dendritic spine morphogenesis (GO:0060997)3.20437588
48regulation of cilium movement (GO:0003352)3.18544881
49high-density lipoprotein particle remodeling (GO:0034375)3.17731997
50positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.17490758
51epithelial cell differentiation involved in kidney development (GO:0035850)3.16677337
52neurotransmitter transport (GO:0006836)3.16260837
53regulation of glucokinase activity (GO:0033131)3.16013588
54regulation of hexokinase activity (GO:1903299)3.16013588
55regulation of excitatory postsynaptic membrane potential (GO:0060079)3.13353806
56positive regulation of membrane potential (GO:0045838)3.12700476
57regulation of neurotransmitter secretion (GO:0046928)3.12439762
58neuromuscular process controlling balance (GO:0050885)3.12236403
59cell communication by electrical coupling (GO:0010644)3.11873144
60regulation of axon guidance (GO:1902667)3.09784713
61glomerulus development (GO:0032835)3.09769804
62regulation of postsynaptic membrane potential (GO:0060078)3.09739161
63gamma-aminobutyric acid transport (GO:0015812)3.09107499
64postsynaptic membrane organization (GO:0001941)3.07703834
65vesicle transport along microtubule (GO:0047496)3.07469474
66dendrite morphogenesis (GO:0048813)3.05406487
67membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.04533913
68positive regulation of synapse maturation (GO:0090129)3.03828601
69regulation of synaptic plasticity (GO:0048167)3.01289775
70reverse cholesterol transport (GO:0043691)2.99976939
71pyrimidine nucleobase catabolic process (GO:0006208)2.99911445
72negative regulation of cytosolic calcium ion concentration (GO:0051481)2.99838142
73cerebellar Purkinje cell differentiation (GO:0021702)2.98822225
74positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.97429340
75chemosensory behavior (GO:0007635)2.94962405
76neuromuscular process controlling posture (GO:0050884)2.93537817
77membrane depolarization during action potential (GO:0086010)2.93238842
78presynaptic membrane assembly (GO:0097105)2.90338877
79neuronal action potential (GO:0019228)2.89256348
80regulation of neurotransmitter transport (GO:0051588)2.87980990
81presynaptic membrane organization (GO:0097090)2.87309699
82membrane hyperpolarization (GO:0060081)2.85796452
83cell migration in hindbrain (GO:0021535)2.85777047
84epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.85261818
85behavioral defense response (GO:0002209)2.85041906
86behavioral fear response (GO:0001662)2.85041906
87organelle transport along microtubule (GO:0072384)2.84417597
88regulation of neurotransmitter levels (GO:0001505)2.84044548
89response to histamine (GO:0034776)2.80756218
90long-term synaptic potentiation (GO:0060291)2.80465272
91positive regulation of neurotransmitter transport (GO:0051590)2.79078966
92regulation of clathrin-mediated endocytosis (GO:2000369)2.76425867
93regulation of axon extension involved in axon guidance (GO:0048841)2.75908741
94cardiac right ventricle morphogenesis (GO:0003215)2.75103347
95membrane depolarization (GO:0051899)2.75060501
96gamma-aminobutyric acid signaling pathway (GO:0007214)2.74810680
97transmission of nerve impulse (GO:0019226)2.74143754
98neuromuscular process (GO:0050905)2.73859452
99startle response (GO:0001964)2.73448584
100glycerophospholipid catabolic process (GO:0046475)2.73125283
101regulation of rhodopsin mediated signaling pathway (GO:0022400)2.72983354
102mating behavior (GO:0007617)2.72445721
103glycine transport (GO:0015816)2.72265563
104regulation of calcium ion-dependent exocytosis (GO:0017158)2.70519725
105regulation of synaptic transmission, glutamatergic (GO:0051966)2.70506159
106response to auditory stimulus (GO:0010996)2.70205587
107positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.70127994
108synaptic transmission (GO:0007268)2.69587568
109regulation of cholesterol esterification (GO:0010872)2.69527724
110synapse assembly (GO:0007416)2.68288610
111positive regulation of potassium ion transmembrane transport (GO:1901381)2.68214766
112dopamine receptor signaling pathway (GO:0007212)2.67124536
113fear response (GO:0042596)2.66935473
114regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.66810191
115bile acid biosynthetic process (GO:0006699)2.66087443
116rhodopsin mediated signaling pathway (GO:0016056)2.65671368
117suckling behavior (GO:0001967)2.64528474
118nucleobase catabolic process (GO:0046113)2.61564465
119detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.60969174
120keratinocyte development (GO:0003334)2.60820616
121axoneme assembly (GO:0035082)2.57803583
122vagina development (GO:0060068)2.57618640
123L-fucose metabolic process (GO:0042354)2.57494695
124L-fucose catabolic process (GO:0042355)2.57494695
125fucose catabolic process (GO:0019317)2.57494695
126heme transport (GO:0015886)2.55502555
127uterus development (GO:0060065)2.53120815
128glycosphingolipid biosynthetic process (GO:0006688)2.52372459
129regulation of microtubule-based movement (GO:0060632)2.51108529
130iron coordination entity transport (GO:1901678)2.50857166
131positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.50604791
132epithelial cilium movement (GO:0003351)2.45549479
133water-soluble vitamin biosynthetic process (GO:0042364)2.44183129
134negative regulation of synaptic transmission, GABAergic (GO:0032229)2.44150073
135cellular response to leptin stimulus (GO:0044320)2.42929046
136piRNA metabolic process (GO:0034587)2.40975289
137positive regulation of glycolytic process (GO:0045821)2.40136292
138C4-dicarboxylate transport (GO:0015740)2.40085079
139serotonin metabolic process (GO:0042428)2.38861750
140G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.37827960
141establishment of pigment granule localization (GO:0051905)2.37403163
142short-chain fatty acid metabolic process (GO:0046459)2.37211319
143nonmotile primary cilium assembly (GO:0035058)2.36716029
144embryonic retina morphogenesis in camera-type eye (GO:0060059)2.33762958
145female genitalia development (GO:0030540)2.32634163
146auditory receptor cell stereocilium organization (GO:0060088)2.31613987
147reflex (GO:0060004)2.30594520
148prostate gland growth (GO:0060736)2.30086941
149cilium movement (GO:0003341)2.30014651
150branched-chain amino acid catabolic process (GO:0009083)2.29328094
151action potential (GO:0001508)2.29216726
152endocrine pancreas development (GO:0031018)2.28178528
153otic vesicle formation (GO:0030916)2.27913314
154cellular biogenic amine catabolic process (GO:0042402)2.26237077
155amine catabolic process (GO:0009310)2.26237077
156regulation of female receptivity (GO:0045924)2.25764317
157nitric oxide mediated signal transduction (GO:0007263)2.25379096
158phospholipid homeostasis (GO:0055091)2.24925288
159detection of light stimulus involved in visual perception (GO:0050908)2.24651148
160detection of light stimulus involved in sensory perception (GO:0050962)2.24651148
161phospholipid efflux (GO:0033700)2.24342096
162norepinephrine metabolic process (GO:0042415)2.23237236
163response to leptin (GO:0044321)2.21885821
164regulation of action potential (GO:0098900)2.21652096
165establishment of melanosome localization (GO:0032401)2.20723294
166pigment granule transport (GO:0051904)2.20603686
167polyol catabolic process (GO:0046174)2.19793185
168pigment granule localization (GO:0051875)2.18248158
169positive regulation of meiosis (GO:0045836)2.17854427
170protein localization to cilium (GO:0061512)2.15746887
171dopamine transport (GO:0015872)2.15376963
172erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.15067276
173L-phenylalanine catabolic process (GO:0006559)2.15067276
174auditory behavior (GO:0031223)2.14858584
175limb bud formation (GO:0060174)2.14248855
176regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.13587046
177intestinal epithelial cell development (GO:0060576)2.13072914
178primary amino compound metabolic process (GO:1901160)2.12069319
179response to dietary excess (GO:0002021)2.11777233
180toxin metabolic process (GO:0009404)2.11507227
181negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.11479266

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.62561602
2GBX2_23144817_ChIP-Seq_PC3_Human3.21008701
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.00837036
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.93805425
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87289614
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64508051
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64508051
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.60163666
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55422383
10* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.51784826
11MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51160366
12* REST_21632747_ChIP-Seq_MESCs_Mouse2.46579463
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.45332704
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38667810
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.35265754
16DROSHA_22980978_ChIP-Seq_HELA_Human2.28573727
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26946350
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.25263150
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.24908693
20ER_23166858_ChIP-Seq_MCF-7_Human2.24505524
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.12918010
22POU3F2_20337985_ChIP-ChIP_501MEL_Human2.11234705
23RARB_27405468_Chip-Seq_BRAIN_Mouse2.05144717
24VDR_22108803_ChIP-Seq_LS180_Human2.04755916
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.03688542
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.99932977
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.94988150
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.93748462
29SALL1_21062744_ChIP-ChIP_HESCs_Human1.83312385
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.82630608
31ESR1_20079471_ChIP-ChIP_T-47D_Human1.65999425
32FUS_26573619_Chip-Seq_HEK293_Human1.65640648
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.65626077
34* SMAD4_21799915_ChIP-Seq_A2780_Human1.64271569
35PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61516969
36NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.59067808
37NR3C1_23031785_ChIP-Seq_PC12_Mouse1.57274906
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56401749
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.56312896
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.55493687
41ZNF274_21170338_ChIP-Seq_K562_Hela1.55323188
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54413526
43ESR1_21235772_ChIP-Seq_MCF-7_Human1.49406252
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.48256916
45BCAT_22108803_ChIP-Seq_LS180_Human1.45262376
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.45187955
47AR_21572438_ChIP-Seq_LNCaP_Human1.43844509
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.42153414
49EWS_26573619_Chip-Seq_HEK293_Human1.40018456
50* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.38595975
51TP53_22573176_ChIP-Seq_HFKS_Human1.37324458
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.36814721
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33692267
54BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32738970
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32573228
56P300_19829295_ChIP-Seq_ESCs_Human1.31028746
57SOX2_21211035_ChIP-Seq_LN229_Gbm1.30102811
58IGF1R_20145208_ChIP-Seq_DFB_Human1.30084421
59TCF4_22108803_ChIP-Seq_LS180_Human1.29375714
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28806906
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.28409896
62CBP_20019798_ChIP-Seq_JUKART_Human1.28409896
63* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26976370
64* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.26937222
65RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26892404
66SMAD_19615063_ChIP-ChIP_OVARY_Human1.26404630
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.26232694
68* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.25728885
69STAT3_23295773_ChIP-Seq_U87_Human1.22869866
70TAF15_26573619_Chip-Seq_HEK293_Human1.22616004
71PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22455239
72EGR1_23403033_ChIP-Seq_LIVER_Mouse1.22348657
73RING1B_27294783_Chip-Seq_NPCs_Mouse1.20836228
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.20427388
75AR_25329375_ChIP-Seq_VCAP_Human1.20351036
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20204464
77KDM2B_26808549_Chip-Seq_K562_Human1.18717715
78* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.18698032
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17878648
80AR_19668381_ChIP-Seq_PC3_Human1.17302223
81* AHR_22903824_ChIP-Seq_MCF-7_Human1.15098514
82SOX2_19829295_ChIP-Seq_ESCs_Human1.14138713
83NANOG_19829295_ChIP-Seq_ESCs_Human1.14138713
84SMAD4_21741376_ChIP-Seq_EPCs_Human1.13988999
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13584751
86PIAS1_25552417_ChIP-Seq_VCAP_Human1.12959399
87TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12817930
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12500294
89CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12365531
90CBX2_27304074_Chip-Seq_ESCs_Mouse1.12265794
91SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11310729
92SMAD3_21741376_ChIP-Seq_HESCs_Human1.10782605
93ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.10728157
94CDX2_19796622_ChIP-Seq_MESCs_Mouse1.10454075
95EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.10011069
96* ARNT_22903824_ChIP-Seq_MCF-7_Human1.09811126
97P53_22387025_ChIP-Seq_ESCs_Mouse1.09385654
98YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08833977
99KLF5_20875108_ChIP-Seq_MESCs_Mouse1.08552082
100GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06654661
101SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06375859
102SMAD4_21741376_ChIP-Seq_HESCs_Human1.05567147
103VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04299355
104TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03958239
105RNF2_27304074_Chip-Seq_NSC_Mouse1.03257666
106TCF4_23295773_ChIP-Seq_U87_Human1.03123991
107SMAD3_21741376_ChIP-Seq_ESCs_Human1.02882050
108HTT_18923047_ChIP-ChIP_STHdh_Human1.02420978
109WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.01639378
110NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01210942
111P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00877460
112EZH2_27294783_Chip-Seq_NPCs_Mouse1.00838305
113FLI1_21867929_ChIP-Seq_TH2_Mouse1.00326843
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97952290
115TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96182611
116RUNX2_22187159_ChIP-Seq_PCA_Human0.95679491
117PRDM14_20953172_ChIP-Seq_ESCs_Human0.94682791
118ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94277283
119DNAJC2_21179169_ChIP-ChIP_NT2_Human0.93383110
120EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.92388815
121TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92105464
122EP300_21415370_ChIP-Seq_HL-1_Mouse0.91886654
123TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91637287
124CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.90277412
125* NANOG_18555785_Chip-Seq_ESCs_Mouse0.89221499
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.88766895
127CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.88015026
128RXR_22108803_ChIP-Seq_LS180_Human0.87578137
129TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87328267
130POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87328267
131UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86638125
132TET1_21490601_ChIP-Seq_MESCs_Mouse0.86615510

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.97373425
2MP0003880_abnormal_central_pattern4.35695506
3MP0003635_abnormal_synaptic_transmissio3.80036436
4MP0004270_analgesia3.45398756
5MP0002063_abnormal_learning/memory/cond3.08311690
6MP0001968_abnormal_touch/_nociception2.98265169
7MP0009745_abnormal_behavioral_response2.94352412
8MP0002735_abnormal_chemical_nociception2.79808186
9MP0005423_abnormal_somatic_nervous2.78004831
10MP0002064_seizures2.71216188
11MP0002734_abnormal_mechanical_nocicepti2.63328234
12MP0002572_abnormal_emotion/affect_behav2.57719704
13MP0009046_muscle_twitch2.56927139
14MP0003195_calcinosis2.51909837
15MP0001486_abnormal_startle_reflex2.50898093
16MP0002272_abnormal_nervous_system2.39736643
17MP0005551_abnormal_eye_electrophysiolog2.27466527
18MP0002736_abnormal_nociception_after2.22985086
19MP0008877_abnormal_DNA_methylation2.20955291
20MP0002733_abnormal_thermal_nociception2.11270896
21MP0001440_abnormal_grooming_behavior2.05810695
22MP0001501_abnormal_sleep_pattern2.04633713
23MP0002184_abnormal_innervation2.02459063
24MP0001970_abnormal_pain_threshold2.01280462
25MP0002909_abnormal_adrenal_gland1.92288584
26MP0006276_abnormal_autonomic_nervous1.92176177
27MP0004858_abnormal_nervous_system1.89558749
28MP0002067_abnormal_sensory_capabilities1.85078686
29MP0000778_abnormal_nervous_system1.84884626
30MP0001984_abnormal_olfaction1.82254199
31MP0010386_abnormal_urinary_bladder1.81874106
32MP0008995_early_reproductive_senescence1.81025176
33MP0009780_abnormal_chondrocyte_physiolo1.79667234
34MP0006072_abnormal_retinal_apoptosis1.79473332
35MP0002822_catalepsy1.66295354
36MP0003787_abnormal_imprinting1.65716148
37MP0004811_abnormal_neuron_physiology1.61315917
38MP0003123_paternal_imprinting1.59254629
39MP0002882_abnormal_neuron_morphology1.58641654
40MP0002557_abnormal_social/conspecific_i1.57126336
41MP0008569_lethality_at_weaning1.57057453
42MP0003329_amyloid_beta_deposits1.55601697
43MP0004885_abnormal_endolymph1.54661964
44MP0010329_abnormal_lipoprotein_level1.54295257
45MP0001502_abnormal_circadian_rhythm1.54077731
46MP0005645_abnormal_hypothalamus_physiol1.51936483
47MP0003011_delayed_dark_adaptation1.51606631
48MP0004133_heterotaxia1.48520358
49MP0003879_abnormal_hair_cell1.48398444
50MP0005623_abnormal_meninges_morphology1.47659449
51MP0008875_abnormal_xenobiotic_pharmacok1.47160115
52MP0000955_abnormal_spinal_cord1.45388444
53MP0004924_abnormal_behavior1.41207074
54MP0005386_behavior/neurological_phenoty1.41207074
55MP0005646_abnormal_pituitary_gland1.37625276
56MP0002229_neurodegeneration1.36589227
57MP0000427_abnormal_hair_cycle1.35819790
58MP0002066_abnormal_motor_capabilities/c1.34544042
59MP0005253_abnormal_eye_physiology1.31818529
60MP0001905_abnormal_dopamine_level1.31043007
61MP0003121_genomic_imprinting1.24787555
62MP0001485_abnormal_pinna_reflex1.19357655
63MP0003283_abnormal_digestive_organ1.19163852
64MP0000639_abnormal_adrenal_gland1.18709321
65MP0002653_abnormal_ependyma_morphology1.18042516
66MP0005085_abnormal_gallbladder_physiolo1.16361292
67MP0003122_maternal_imprinting1.15374926
68MP0003890_abnormal_embryonic-extraembry1.14911499
69MP0002752_abnormal_somatic_nervous1.13312057
70MP0002160_abnormal_reproductive_system1.10180425
71MP0002090_abnormal_vision1.08016648
72MP0005365_abnormal_bile_salt1.07160139
73MP0000462_abnormal_digestive_system1.05198669
74MP0003633_abnormal_nervous_system1.04134216
75MP0002152_abnormal_brain_morphology1.03736098
76MP0000538_abnormal_urinary_bladder1.03617292
77MP0001963_abnormal_hearing_physiology1.02079226
78MP0002102_abnormal_ear_morphology1.01961451
79MP0004043_abnormal_pH_regulation1.01905363
80MP0002751_abnormal_autonomic_nervous0.96161700
81MP0008961_abnormal_basal_metabolism0.96144978
82MP0000383_abnormal_hair_follicle0.94661321
83MP0001944_abnormal_pancreas_morphology0.94495797
84MP0003634_abnormal_glial_cell0.93986005
85MP0001188_hyperpigmentation0.91982794
86MP0003631_nervous_system_phenotype0.90373615
87MP0002277_abnormal_respiratory_mucosa0.90289757
88MP0000013_abnormal_adipose_tissue0.89560992
89MP0005670_abnormal_white_adipose0.88740150
90MP0008872_abnormal_physiological_respon0.88562194
91MP0002638_abnormal_pupillary_reflex0.88444180
92MP0005195_abnormal_posterior_eye0.88241595
93MP0001348_abnormal_lacrimal_gland0.87947732
94MP0002069_abnormal_eating/drinking_beha0.87588065
95MP0005220_abnormal_exocrine_pancreas0.87224429
96MP0005499_abnormal_olfactory_system0.86304257
97MP0005394_taste/olfaction_phenotype0.86304257
98MP0004142_abnormal_muscle_tone0.86004042
99MP0004085_abnormal_heartbeat0.84193988
100MP0000230_abnormal_systemic_arterial0.83949910
101MP0005084_abnormal_gallbladder_morpholo0.82508685
102MP0004742_abnormal_vestibular_system0.82467617
103MP0005535_abnormal_body_temperature0.81030658
104MP0002938_white_spotting0.80071930
105MP0009840_abnormal_foam_cell0.79747697
106MP0001529_abnormal_vocalization0.79653282
107MP0004084_abnormal_cardiac_muscle0.79620999
108MP0000534_abnormal_ureter_morphology0.79394136
109MP0000569_abnormal_digit_pigmentation0.79335289
110MP0000647_abnormal_sebaceous_gland0.78784635
111MP0003878_abnormal_ear_physiology0.78354322
112MP0005377_hearing/vestibular/ear_phenot0.78354322
113MP0005332_abnormal_amino_acid0.78237899
114MP0005367_renal/urinary_system_phenotyp0.78025279
115MP0000516_abnormal_urinary_system0.78025279
116MP0002876_abnormal_thyroid_physiology0.77819932
117MP0004145_abnormal_muscle_electrophysio0.77072656
118MP0004484_altered_response_of0.76614382
119MP0004036_abnormal_muscle_relaxation0.75347332
120MP0005187_abnormal_penis_morphology0.74688617
121MP0001664_abnormal_digestion0.74205472
122MP0003119_abnormal_digestive_system0.73518296
123MP0004019_abnormal_vitamin_homeostasis0.72863084
124MP0004233_abnormal_muscle_weight0.66249907
125MP0008874_decreased_physiological_sensi0.65561283
126MP0001299_abnormal_eye_distance/0.65453154
127MP0003183_abnormal_peptide_metabolism0.64596574
128MP0004215_abnormal_myocardial_fiber0.63367364
129MP0004510_myositis0.62845843
130MP0002234_abnormal_pharynx_morphology0.61617730
131MP0001986_abnormal_taste_sensitivity0.61341598
132MP0003632_abnormal_nervous_system0.61326756
133MP0003137_abnormal_impulse_conducting0.60377239
134MP0000604_amyloidosis0.60214224
135MP0002837_dystrophic_cardiac_calcinosis0.58174571
136MP0000631_abnormal_neuroendocrine_gland0.58001542
137MP0001177_atelectasis0.56858101
138MP0001765_abnormal_ion_homeostasis0.55947263

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.10391991
2Myokymia (HP:0002411)5.81212311
3Visual hallucinations (HP:0002367)4.85143415
4Focal seizures (HP:0007359)4.65466158
5Febrile seizures (HP:0002373)4.07253542
6Epileptic encephalopathy (HP:0200134)4.02082833
7Progressive cerebellar ataxia (HP:0002073)3.86138808
8Chronic hepatic failure (HP:0100626)3.85164819
9Focal segmental glomerulosclerosis (HP:0000097)3.80681167
10Atonic seizures (HP:0010819)3.76335608
11Congenital stationary night blindness (HP:0007642)3.71696405
12Supranuclear gaze palsy (HP:0000605)3.49934389
13Action tremor (HP:0002345)3.45858634
14Absence seizures (HP:0002121)3.45551909
15Central scotoma (HP:0000603)3.22799719
16Abnormality of macular pigmentation (HP:0008002)3.19307641
17Pancreatic cysts (HP:0001737)3.18852938
18Ankle clonus (HP:0011448)3.16935915
19Mesangial abnormality (HP:0001966)3.16468349
20Dialeptic seizures (HP:0011146)3.11580524
21Mutism (HP:0002300)3.11265724
22Generalized tonic-clonic seizures (HP:0002069)3.11185736
23Concave nail (HP:0001598)3.11062706
24Abnormality of midbrain morphology (HP:0002418)3.10813349
25Molar tooth sign on MRI (HP:0002419)3.10813349
26Bony spicule pigmentary retinopathy (HP:0007737)3.10640583
27Medial flaring of the eyebrow (HP:0010747)3.10563759
28True hermaphroditism (HP:0010459)3.10437850
29Ketoacidosis (HP:0001993)3.01240911
30Abnormal rod and cone electroretinograms (HP:0008323)2.92891530
31Glomerulosclerosis (HP:0000096)2.88820938
32Polyphagia (HP:0002591)2.86787007
33Hypothermia (HP:0002045)2.85527192
34Depression (HP:0000716)2.82881215
35Increased circulating renin level (HP:0000848)2.80067871
36Rapidly progressive (HP:0003678)2.76515253
37Pheochromocytoma (HP:0002666)2.71186851
38Hyperinsulinemic hypoglycemia (HP:0000825)2.69560675
39Pancreatic fibrosis (HP:0100732)2.67739291
40Truncal ataxia (HP:0002078)2.67112169
41Abnormal pancreas size (HP:0012094)2.66401586
42Broad-based gait (HP:0002136)2.66368344
43Ketosis (HP:0001946)2.63631447
44Nephrogenic diabetes insipidus (HP:0009806)2.60433010
45Papilledema (HP:0001085)2.59544340
46Abnormality of the lower motor neuron (HP:0002366)2.58377765
47Congenital primary aphakia (HP:0007707)2.57989939
48Hypoglycemic coma (HP:0001325)2.55887031
49Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.53029526
50Poor eye contact (HP:0000817)2.52481851
51Absent rod-and cone-mediated responses on ERG (HP:0007688)2.52236106
52Ventricular fibrillation (HP:0001663)2.50076910
53Anxiety (HP:0000739)2.49890294
54Nephronophthisis (HP:0000090)2.49718277
55Hypomagnesemia (HP:0002917)2.49631761
56Limb dystonia (HP:0002451)2.48029749
57Testicular neoplasm (HP:0010788)2.47259936
58Urinary bladder sphincter dysfunction (HP:0002839)2.44995151
59Renal cortical cysts (HP:0000803)2.44356998
60Abnormality of calcium-phosphate metabolism (HP:0100530)2.44202992
61Drooling (HP:0002307)2.42506062
62Excessive salivation (HP:0003781)2.42506062
63Abnormality of the renal cortex (HP:0011035)2.40948381
64Impaired vibration sensation in the lower limbs (HP:0002166)2.40856200
65Methylmalonic acidemia (HP:0002912)2.40148142
66Abnormal albumin level (HP:0012116)2.39931463
67Hypoalbuminemia (HP:0003073)2.39931463
68Large for gestational age (HP:0001520)2.39839965
69Male pseudohermaphroditism (HP:0000037)2.39346044
70Amblyopia (HP:0000646)2.38709075
71Spontaneous abortion (HP:0005268)2.35268883
72Epileptiform EEG discharges (HP:0011182)2.34446552
73Scotoma (HP:0000575)2.33827514
74Gaze-evoked nystagmus (HP:0000640)2.32870535
75Dyschromatopsia (HP:0007641)2.32294383
76Postural instability (HP:0002172)2.30806501
77Abnormal eating behavior (HP:0100738)2.29920749
78Progressive inability to walk (HP:0002505)2.29740097
79Hypoglycemic seizures (HP:0002173)2.29219019
80Impaired social interactions (HP:0000735)2.28800386
81Abnormal social behavior (HP:0012433)2.28800386
82Agitation (HP:0000713)2.27871563
83EEG with generalized epileptiform discharges (HP:0011198)2.27673682
84Genetic anticipation (HP:0003743)2.27493710
85Gait imbalance (HP:0002141)2.26933842
86Dysmetria (HP:0001310)2.26829794
87Cystic liver disease (HP:0006706)2.24378702
88Neuroendocrine neoplasm (HP:0100634)2.23991537
89Dysdiadochokinesis (HP:0002075)2.23917855
90Stage 5 chronic kidney disease (HP:0003774)2.20586592
91Spastic gait (HP:0002064)2.19774776
92Hyperventilation (HP:0002883)2.19384255
93Enlarged penis (HP:0000040)2.18347580
94Hyperglycinemia (HP:0002154)2.16483851
95Hypsarrhythmia (HP:0002521)2.14917125
96Abnormality of the corticospinal tract (HP:0002492)2.14774764
97Neurofibrillary tangles (HP:0002185)2.11834461
98Urinary urgency (HP:0000012)2.11598964
99Torticollis (HP:0000473)2.10249343
100Abnormality of the renal medulla (HP:0100957)2.09488988
101Retinal atrophy (HP:0001105)2.09348159
102Bradykinesia (HP:0002067)2.08069506
103Gonadal dysgenesis (HP:0000133)2.08037672
104Abolished electroretinogram (ERG) (HP:0000550)2.07252476
105J-shaped sella turcica (HP:0002680)2.07231420
106Intention tremor (HP:0002080)2.05615080
107Hyperglycemia (HP:0003074)2.05011708
108Cerebral inclusion bodies (HP:0100314)2.04614065
109Choroideremia (HP:0001139)2.04528275
110Abnormal drinking behavior (HP:0030082)1.99238090
111Polydipsia (HP:0001959)1.99238090
112Nephrotic syndrome (HP:0000100)1.99166712
113Lower limb muscle weakness (HP:0007340)1.99079835
114Hyperglycinuria (HP:0003108)1.98959326
115Failure to thrive in infancy (HP:0001531)1.97521163
116Absent/shortened dynein arms (HP:0200106)1.96234467
117Dynein arm defect of respiratory motile cilia (HP:0012255)1.96234467
118Aplasia/Hypoplasia of the tibia (HP:0005772)1.95804431
119Megalencephaly (HP:0001355)1.95681227
120Decreased central vision (HP:0007663)1.94991704
121Abnormality of alanine metabolism (HP:0010916)1.94478795
122Hyperalaninemia (HP:0003348)1.94478795
123Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.94478795
124Aplasia/Hypoplasia of the tongue (HP:0010295)1.94158907
125Insomnia (HP:0100785)1.93321743
126Poor coordination (HP:0002370)1.93068376
127Abnormal EKG (HP:0003115)1.92550394
128Inability to walk (HP:0002540)1.92475746
129Tachypnea (HP:0002789)1.92383915
130Disproportionate short-trunk short stature (HP:0003521)1.92053727
131Diplopia (HP:0000651)1.91751461
132Abnormality of binocular vision (HP:0011514)1.91751461
133Tubulointerstitial nephritis (HP:0001970)1.89409712
134Sex reversal (HP:0012245)1.88544482
135Abnormal sex determination (HP:0012244)1.88544482
136Impaired smooth pursuit (HP:0007772)1.87534062
137Abnormality of magnesium homeostasis (HP:0004921)1.87475956
138Genital tract atresia (HP:0001827)1.86434791
139Fetal akinesia sequence (HP:0001989)1.86358080
140Aqueductal stenosis (HP:0002410)1.85736280
141Bundle branch block (HP:0011710)1.85589126
142Hypercortisolism (HP:0001578)1.84914165
143Absent speech (HP:0001344)1.84540818
144Focal dystonia (HP:0004373)1.84210012
145Vaginal atresia (HP:0000148)1.83052405
146Type II lissencephaly (HP:0007260)1.82663300
147Keratoconus (HP:0000563)1.82258191
148Increased corneal curvature (HP:0100692)1.82258191
149Methylmalonic aciduria (HP:0012120)1.81366850
150Degeneration of the lateral corticospinal tracts (HP:0002314)1.81034868
151Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.81034868
152Hemiparesis (HP:0001269)1.80576403
153Abnormality of vitamin B metabolism (HP:0004340)1.80263030
154Tongue fasciculations (HP:0001308)1.80091906
155Abnormal respiratory epithelium morphology (HP:0012253)1.79556228
156Abnormal respiratory motile cilium morphology (HP:0005938)1.79556228
157Hip dysplasia (HP:0001385)1.79301220
158Type II diabetes mellitus (HP:0005978)1.78604331
159Hemiplegia (HP:0002301)1.78330432
160Anosmia (HP:0000458)1.77660456
161Abnormality of the pancreatic islet cells (HP:0006476)1.77574211
162Abnormality of endocrine pancreas physiology (HP:0012093)1.77574211
163Retinal dysplasia (HP:0007973)1.77426194
164Intrahepatic cholestasis (HP:0001406)1.76583075
165Abnormality of serine family amino acid metabolism (HP:0010894)1.74979074
166Abnormality of glycine metabolism (HP:0010895)1.74979074
167Abnormal ciliary motility (HP:0012262)1.73331242
168Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.70540825
169Muscular hypotonia of the trunk (HP:0008936)1.68772762
170Severe muscular hypotonia (HP:0006829)1.67876704
171Abnormality of the vitamin B12 metabolism (HP:0004341)1.67626030
172Polyuria (HP:0000103)1.67088805
173Decreased circulating renin level (HP:0003351)1.64574431
174Cerebellar dysplasia (HP:0007033)1.64472580

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.34867609
2NTRK34.69558800
3MARK13.64804052
4MAP3K93.58721160
5MAP3K43.01045812
6EPHA42.75379654
7TRIM282.74041989
8MINK12.61101483
9MAP2K72.45572848
10BMPR1B2.17771282
11PAK62.13383575
12NTRK12.11536620
13MAP4K22.10270639
14PRKD32.09629073
15FGFR22.06647747
16KSR21.92531537
17GRK51.89672983
18PDK21.82214334
19WNK41.79840991
20DAPK21.77899574
21NTRK21.76683263
22PIK3CA1.64395314
23MAP2K41.62495527
24ADRBK21.60133871
25CDK51.54923055
26MAPK131.54758852
27MAP3K121.53746071
28ACVR1B1.50877056
29CAMKK11.49133355
30OXSR11.47329644
31CASK1.47008107
32PINK11.40960285
33RIPK41.40217157
34ARAF1.37482284
35TAOK31.35354722
36SIK21.35186248
37PHKG11.33997039
38PHKG21.33997039
39PRPF4B1.32157827
40STK381.29059986
41LATS21.27424674
42NUAK11.22521762
43MAP3K21.22228418
44PRKCG1.21037092
45KSR11.20460520
46PLK21.18501480
47BCR1.17155636
48STK391.17052110
49NEK11.16025808
50MAP3K131.14588880
51PAK31.14466237
52CAMK2B1.13776639
53AKT31.12720205
54MAPKAPK31.11529577
55PNCK1.06442205
56SGK4941.05153897
57SGK2231.05153897
58STK38L1.04783981
59RET1.01935240
60DAPK11.01529046
61LMTK21.00977781
62UHMK10.98930294
63CAMKK20.98868241
64CSNK1G10.98470134
65CSNK1G30.97142968
66MUSK0.96123182
67CAMK2A0.93854698
68SGK20.93788068
69TNK20.92563035
70PRKCH0.92065428
71PKN20.89147712
72TNIK0.88222237
73EIF2AK30.85412892
74EPHB20.85373495
75CDK190.85058303
76NME10.84403037
77DYRK20.83875491
78TIE10.83609511
79GRK10.82113845
80CDK180.81390064
81SGK30.81334681
82FES0.80505620
83PRKCE0.80362921
84CDK150.80273221
85CDK140.78927830
86DYRK1A0.78657787
87CSNK1G20.78217278
88FER0.76855135
89WNK10.74865961
90ZAK0.72660131
91STK110.72630608
92CAMK10.70978997
93PBK0.69877017
94SGK10.69185187
95CDK11A0.68307229
96PRKCZ0.66750541
97TAOK10.66266202
98MARK20.66067060
99CDC42BPA0.65710965
100CSNK1D0.64942928
101WNK30.64064260
102CSNK1A10.61538383
103ALK0.59297232
104SIK30.59076737
105PASK0.57206853
106CSNK1A1L0.54729872
107MAP3K10.54309894
108INSRR0.54273070
109PKN10.54144207
110MKNK20.53560664
111PDPK10.53499721
112PRKACA0.53494645
113TYRO30.52885324
114PDK10.52791639
115ERBB30.52711617
116PTK2B0.51724158
117RPS6KA20.51164157
118CAMK2G0.49630871
119BMPR20.48645423
120CAMK2D0.48444154
121TSSK60.47728707
122PRKCI0.47727858
123RAF10.47358942
124CAMK1G0.46952350
125MAP2K10.46619526
126PRKAA10.46594021
127RPS6KA30.45396936
128MAPK100.44035467
129MAPKAPK50.44013879
130MAP3K70.43683647
131RPS6KB10.42457205
132CHUK0.42333951
133PRKCA0.42302158
134ADRBK10.42014792
135PRKAA20.40549047
136PRKACB0.39868221
137MAP3K60.39494469
138MYLK0.38690665
139ROCK10.38517239
140NEK60.37620922
141OBSCN0.37112247
142SCYL20.36924072
143PRKG10.36570194
144CSNK1E0.36155972
145ROCK20.34335368

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.32293369
2Butanoate metabolism_Homo sapiens_hsa006503.26498806
3Phototransduction_Homo sapiens_hsa047443.21600762
4Maturity onset diabetes of the young_Homo sapiens_hsa049503.15892544
5Synaptic vesicle cycle_Homo sapiens_hsa047213.15366849
6Nicotine addiction_Homo sapiens_hsa050333.14120643
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.81213484
8Olfactory transduction_Homo sapiens_hsa047402.80569977
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.66584744
10GABAergic synapse_Homo sapiens_hsa047272.53786152
11Circadian entrainment_Homo sapiens_hsa047132.53195053
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.41969566
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.37745807
14Morphine addiction_Homo sapiens_hsa050322.33650214
15Long-term potentiation_Homo sapiens_hsa047202.32833163
16Glutamatergic synapse_Homo sapiens_hsa047242.28277386
17Amphetamine addiction_Homo sapiens_hsa050312.14549629
18Insulin secretion_Homo sapiens_hsa049112.13453207
19Propanoate metabolism_Homo sapiens_hsa006402.05762559
20Dopaminergic synapse_Homo sapiens_hsa047282.01259886
21Salivary secretion_Homo sapiens_hsa049701.95897720
22Cholinergic synapse_Homo sapiens_hsa047251.89217948
23Taste transduction_Homo sapiens_hsa047421.82568091
24Gastric acid secretion_Homo sapiens_hsa049711.81978467
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.77701984
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.75850515
27Serotonergic synapse_Homo sapiens_hsa047261.69533660
28Tryptophan metabolism_Homo sapiens_hsa003801.62595762
29Caffeine metabolism_Homo sapiens_hsa002321.60542299
30Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.60188004
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.59956407
32Renin secretion_Homo sapiens_hsa049241.58887380
33Fatty acid elongation_Homo sapiens_hsa000621.57569818
34Cocaine addiction_Homo sapiens_hsa050301.54169644
35Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.51905481
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.51843143
37Linoleic acid metabolism_Homo sapiens_hsa005911.50710563
38Nitrogen metabolism_Homo sapiens_hsa009101.47336124
39Oxytocin signaling pathway_Homo sapiens_hsa049211.45896406
40Chemical carcinogenesis_Homo sapiens_hsa052041.41987601
41Fatty acid degradation_Homo sapiens_hsa000711.41880842
42beta-Alanine metabolism_Homo sapiens_hsa004101.41527831
43Collecting duct acid secretion_Homo sapiens_hsa049661.40435410
44Fatty acid metabolism_Homo sapiens_hsa012121.39681437
45alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.38940216
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.36546979
47Calcium signaling pathway_Homo sapiens_hsa040201.35745436
48Long-term depression_Homo sapiens_hsa047301.35447196
49Axon guidance_Homo sapiens_hsa043601.34730843
50Peroxisome_Homo sapiens_hsa041461.33261318
51GnRH signaling pathway_Homo sapiens_hsa049121.32978956
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.29710455
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.28780733
54cAMP signaling pathway_Homo sapiens_hsa040241.25875913
55Gap junction_Homo sapiens_hsa045401.22097164
56Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.21157329
57Type II diabetes mellitus_Homo sapiens_hsa049301.21126720
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19843037
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.15819213
60Estrogen signaling pathway_Homo sapiens_hsa049151.13679110
61Phosphatidylinositol signaling system_Homo sapiens_hsa040701.12688202
62Fat digestion and absorption_Homo sapiens_hsa049751.11152199
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.10654513
64Protein export_Homo sapiens_hsa030601.09269299
65Steroid biosynthesis_Homo sapiens_hsa001001.07935302
66cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05721026
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.05698238
68Vitamin digestion and absorption_Homo sapiens_hsa049771.05632419
69ABC transporters_Homo sapiens_hsa020101.04680915
70Vitamin B6 metabolism_Homo sapiens_hsa007501.04441576
71Glioma_Homo sapiens_hsa052141.04293931
72PPAR signaling pathway_Homo sapiens_hsa033201.01175119
73Vibrio cholerae infection_Homo sapiens_hsa051101.00029244
74Retinol metabolism_Homo sapiens_hsa008300.99431473
75Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.98778254
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.97820460
77Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.97521399
78Oxidative phosphorylation_Homo sapiens_hsa001900.97130987
79Melanogenesis_Homo sapiens_hsa049160.93303372
80Thyroid hormone synthesis_Homo sapiens_hsa049180.93208233
81ErbB signaling pathway_Homo sapiens_hsa040120.91758797
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.90103566
83Dilated cardiomyopathy_Homo sapiens_hsa054140.89470519
84Ether lipid metabolism_Homo sapiens_hsa005650.86949140
85Histidine metabolism_Homo sapiens_hsa003400.85033846
86Cardiac muscle contraction_Homo sapiens_hsa042600.84514301
87Dorso-ventral axis formation_Homo sapiens_hsa043200.82216281
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.80126871
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79025985
90Pancreatic secretion_Homo sapiens_hsa049720.78420185
91Oocyte meiosis_Homo sapiens_hsa041140.77417241
92Sphingolipid metabolism_Homo sapiens_hsa006000.75615665
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.75004800
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74936247
95Choline metabolism in cancer_Homo sapiens_hsa052310.72076686
96Sulfur metabolism_Homo sapiens_hsa009200.70401544
97Circadian rhythm_Homo sapiens_hsa047100.68543190
98Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68375471
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67519893
100Ras signaling pathway_Homo sapiens_hsa040140.67518804
101MAPK signaling pathway_Homo sapiens_hsa040100.67362402
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.66090536
103mTOR signaling pathway_Homo sapiens_hsa041500.65576484
104Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65162835
105Glutathione metabolism_Homo sapiens_hsa004800.62110770
106VEGF signaling pathway_Homo sapiens_hsa043700.62050317
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.61751525
108Thyroid hormone signaling pathway_Homo sapiens_hsa049190.61190181
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60729964
110Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59502869
111Tyrosine metabolism_Homo sapiens_hsa003500.58311030
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56539847
113Selenocompound metabolism_Homo sapiens_hsa004500.56404872
114Arginine and proline metabolism_Homo sapiens_hsa003300.55786063
115SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55526648
116Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.55268034
117Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55181486
118Endometrial cancer_Homo sapiens_hsa052130.55004987
119Rap1 signaling pathway_Homo sapiens_hsa040150.54816239
120Renal cell carcinoma_Homo sapiens_hsa052110.53683672
121Endocytosis_Homo sapiens_hsa041440.53617796
122Glucagon signaling pathway_Homo sapiens_hsa049220.53336413
123Parkinsons disease_Homo sapiens_hsa050120.53068976
124Inositol phosphate metabolism_Homo sapiens_hsa005620.51004837
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50149689
126Arachidonic acid metabolism_Homo sapiens_hsa005900.50087119
127Metabolic pathways_Homo sapiens_hsa011000.49205746
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49071683
129Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.48689885
130Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47408957
131Mineral absorption_Homo sapiens_hsa049780.46982361
132Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44666032
133Type I diabetes mellitus_Homo sapiens_hsa049400.44140710
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.43156878
135Pyruvate metabolism_Homo sapiens_hsa006200.43041297
136Basal transcription factors_Homo sapiens_hsa030220.42904348
137Insulin signaling pathway_Homo sapiens_hsa049100.41941823
138Non-small cell lung cancer_Homo sapiens_hsa052230.41174553
139Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40057331
140Alcoholism_Homo sapiens_hsa050340.39566649
141Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.39492262
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39262911
143Chemokine signaling pathway_Homo sapiens_hsa040620.38192989
144Ovarian steroidogenesis_Homo sapiens_hsa049130.37145969
145Wnt signaling pathway_Homo sapiens_hsa043100.33471841
146Prolactin signaling pathway_Homo sapiens_hsa049170.32028793
147Glycerophospholipid metabolism_Homo sapiens_hsa005640.31623525
148Bile secretion_Homo sapiens_hsa049760.31350319
149Regulation of autophagy_Homo sapiens_hsa041400.30562044
150Rheumatoid arthritis_Homo sapiens_hsa053230.29096845
151AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.27621300
152Tight junction_Homo sapiens_hsa045300.27505817

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