

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 9.79932423 |
| 2 | synaptic vesicle maturation (GO:0016188) | 9.02180406 |
| 3 | glutamate secretion (GO:0014047) | 8.44944280 |
| 4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 7.60916357 |
| 5 | synaptic vesicle exocytosis (GO:0016079) | 7.24328894 |
| 6 | regulation of synaptic vesicle exocytosis (GO:2000300) | 7.07232768 |
| 7 | regulation of synaptic vesicle transport (GO:1902803) | 6.14927732 |
| 8 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.88593781 |
| 9 | cellular potassium ion homeostasis (GO:0030007) | 5.84605253 |
| 10 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.84208218 |
| 11 | neurotransmitter secretion (GO:0007269) | 5.55982884 |
| 12 | regulation of neuronal synaptic plasticity (GO:0048168) | 5.44754526 |
| 13 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.41164501 |
| 14 | sodium ion export (GO:0071436) | 5.28835662 |
| 15 | locomotory exploration behavior (GO:0035641) | 5.23113256 |
| 16 | L-amino acid import (GO:0043092) | 5.06538615 |
| 17 | negative regulation of dendrite morphogenesis (GO:0050774) | 4.96912826 |
| 18 | neuronal action potential propagation (GO:0019227) | 4.89497078 |
| 19 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.84184638 |
| 20 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.70646437 |
| 21 | exploration behavior (GO:0035640) | 4.69038195 |
| 22 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.55075065 |
| 23 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.49885343 |
| 24 | cerebellar granule cell differentiation (GO:0021707) | 4.47551449 |
| 25 | amino acid import (GO:0043090) | 4.45920092 |
| 26 | neurotransmitter transport (GO:0006836) | 4.43020312 |
| 27 | positive regulation of synapse maturation (GO:0090129) | 4.39917153 |
| 28 | regulation of neurotransmitter secretion (GO:0046928) | 4.36270707 |
| 29 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.33245826 |
| 30 | synaptic transmission, glutamatergic (GO:0035249) | 4.30637238 |
| 31 | regulation of synaptic plasticity (GO:0048167) | 4.28727405 |
| 32 | protein localization to synapse (GO:0035418) | 4.27974781 |
| 33 | vocalization behavior (GO:0071625) | 4.23413769 |
| 34 | positive regulation of neurotransmitter secretion (GO:0001956) | 4.22651426 |
| 35 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.15837969 |
| 36 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.09985535 |
| 37 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.08642882 |
| 38 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 4.07165285 |
| 39 | regulation of voltage-gated calcium channel activity (GO:1901385) | 4.06634623 |
| 40 | neuron-neuron synaptic transmission (GO:0007270) | 4.06571410 |
| 41 | positive regulation of neurotransmitter transport (GO:0051590) | 4.05683775 |
| 42 | positive regulation of membrane potential (GO:0045838) | 3.98535636 |
| 43 | synaptic vesicle endocytosis (GO:0048488) | 3.97594102 |
| 44 | positive regulation of dendritic spine development (GO:0060999) | 3.97495134 |
| 45 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.96086853 |
| 46 | regulation of neurotransmitter transport (GO:0051588) | 3.89685995 |
| 47 | regulation of synapse structural plasticity (GO:0051823) | 3.89436102 |
| 48 | neuromuscular process controlling balance (GO:0050885) | 3.89107216 |
| 49 | regulation of neurotransmitter levels (GO:0001505) | 3.85408774 |
| 50 | neuronal ion channel clustering (GO:0045161) | 3.83744767 |
| 51 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.83291141 |
| 52 | potassium ion homeostasis (GO:0055075) | 3.82936022 |
| 53 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.82519379 |
| 54 | regulation of ARF protein signal transduction (GO:0032012) | 3.78235331 |
| 55 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.76405097 |
| 56 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.75043984 |
| 57 | long-term memory (GO:0007616) | 3.71749158 |
| 58 | regulation of postsynaptic membrane potential (GO:0060078) | 3.70205074 |
| 59 | layer formation in cerebral cortex (GO:0021819) | 3.69767795 |
| 60 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.69248328 |
| 61 | glutamate receptor signaling pathway (GO:0007215) | 3.63976379 |
| 62 | cell communication by electrical coupling (GO:0010644) | 3.63049207 |
| 63 | vesicle docking involved in exocytosis (GO:0006904) | 3.59868668 |
| 64 | regulation of vesicle fusion (GO:0031338) | 3.59273608 |
| 65 | regulation of dendritic spine development (GO:0060998) | 3.54280997 |
| 66 | potassium ion import (GO:0010107) | 3.54145176 |
| 67 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.54044457 |
| 68 | dendritic spine morphogenesis (GO:0060997) | 3.53330320 |
| 69 | neuromuscular process controlling posture (GO:0050884) | 3.47461107 |
| 70 | activation of protein kinase A activity (GO:0034199) | 3.46971827 |
| 71 | vesicle docking (GO:0048278) | 3.40006995 |
| 72 | gamma-aminobutyric acid transport (GO:0015812) | 3.38065957 |
| 73 | regulation of synapse maturation (GO:0090128) | 3.37989222 |
| 74 | regulation of synaptic transmission (GO:0050804) | 3.35367475 |
| 75 | proline transport (GO:0015824) | 3.35290482 |
| 76 | membrane depolarization during action potential (GO:0086010) | 3.34942380 |
| 77 | membrane depolarization (GO:0051899) | 3.32916408 |
| 78 | acidic amino acid transport (GO:0015800) | 3.31387186 |
| 79 | long-term synaptic potentiation (GO:0060291) | 3.29737645 |
| 80 | central nervous system myelination (GO:0022010) | 3.27230005 |
| 81 | axon ensheathment in central nervous system (GO:0032291) | 3.27230005 |
| 82 | detection of calcium ion (GO:0005513) | 3.27189931 |
| 83 | response to gravity (GO:0009629) | 3.25839929 |
| 84 | cellular sodium ion homeostasis (GO:0006883) | 3.21043583 |
| 85 | synaptic transmission (GO:0007268) | 3.20366233 |
| 86 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.19728193 |
| 87 | postsynaptic membrane organization (GO:0001941) | 3.18903693 |
| 88 | neuron cell-cell adhesion (GO:0007158) | 3.17919974 |
| 89 | dendritic spine organization (GO:0097061) | 3.15716391 |
| 90 | establishment of synaptic vesicle localization (GO:0097480) | 3.14981511 |
| 91 | synaptic vesicle transport (GO:0048489) | 3.14981511 |
| 92 | neuromuscular process (GO:0050905) | 3.10574214 |
| 93 | dicarboxylic acid transport (GO:0006835) | 3.07242954 |
| 94 | acid secretion (GO:0046717) | 3.06652467 |
| 95 | serotonin metabolic process (GO:0042428) | 3.06538023 |
| 96 | regulation of exocytosis (GO:0017157) | 3.06412474 |
| 97 | neurotransmitter uptake (GO:0001504) | 3.05983428 |
| 98 | phosphorelay signal transduction system (GO:0000160) | 3.05383917 |
| 99 | regulation of dendrite morphogenesis (GO:0048814) | 2.99211869 |
| 100 | positive regulation of dendrite development (GO:1900006) | 2.97957455 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.70726089 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.52004930 |
| 3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.42945252 |
| 4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.33375136 |
| 5 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 3.31783693 |
| 6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.21317448 |
| 7 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.20776043 |
| 8 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.97474624 |
| 9 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.95998333 |
| 10 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.95318888 |
| 11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.93264238 |
| 12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.93264238 |
| 13 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.92755397 |
| 14 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.74724943 |
| 15 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.74252290 |
| 16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.73369305 |
| 17 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.72752475 |
| 18 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.70240334 |
| 19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.64727223 |
| 20 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.64127166 |
| 21 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.61762319 |
| 22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.54028576 |
| 23 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.50353759 |
| 24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.47675750 |
| 25 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.45433886 |
| 26 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.45292576 |
| 27 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.38909994 |
| 28 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.97167541 |
| 29 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.86338271 |
| 30 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.85078039 |
| 31 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.74319019 |
| 32 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.71814387 |
| 33 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.64323822 |
| 34 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.61866910 |
| 35 | KDM2B_26808549_Chip-Seq_K562_Human | 1.59937563 |
| 36 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.54950790 |
| 37 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.49979687 |
| 38 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.43561442 |
| 39 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.42906052 |
| 40 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.41900998 |
| 41 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.41654652 |
| 42 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.40728299 |
| 43 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.39571883 |
| 44 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.34332048 |
| 45 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.30520540 |
| 46 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.26563993 |
| 47 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.26189728 |
| 48 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.26097316 |
| 49 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.23203694 |
| 50 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.19771843 |
| 51 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.18338694 |
| 52 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.16352985 |
| 53 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.11455357 |
| 54 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.09815048 |
| 55 | AR_19668381_ChIP-Seq_PC3_Human | 1.08958663 |
| 56 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.03701531 |
| 57 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.00132696 |
| 58 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.99495090 |
| 59 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.98681086 |
| 60 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.97117296 |
| 61 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.96480832 |
| 62 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.95310555 |
| 63 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.94960488 |
| 64 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.94481269 |
| 65 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 0.94243035 |
| 66 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.94183674 |
| 67 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.93344262 |
| 68 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.92470514 |
| 69 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.92329973 |
| 70 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.92251851 |
| 71 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.91761504 |
| 72 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.90723371 |
| 73 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.90478353 |
| 74 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.88316170 |
| 75 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.87084094 |
| 76 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.86209539 |
| 77 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.86111427 |
| 78 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86035055 |
| 79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.85883724 |
| 80 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.85793233 |
| 81 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.85610756 |
| 82 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.83743180 |
| 83 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.81605291 |
| 84 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.80502857 |
| 85 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.79695117 |
| 86 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.79429511 |
| 87 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.79125017 |
| 88 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.77755794 |
| 89 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 0.76967489 |
| 90 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.76958779 |
| 91 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.76793133 |
| 92 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.75998173 |
| 93 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.75091135 |
| 94 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.74979065 |
| 95 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.73250722 |
| 96 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.73038849 |
| 97 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.72288832 |
| 98 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.71287585 |
| 99 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.70732837 |
| 100 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.70322118 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 7.44353751 |
| 2 | MP0003880_abnormal_central_pattern | 5.70236003 |
| 3 | MP0004270_analgesia | 4.67926635 |
| 4 | MP0003635_abnormal_synaptic_transmissio | 4.28611834 |
| 5 | MP0002064_seizures | 3.92802904 |
| 6 | MP0009745_abnormal_behavioral_response | 3.55412106 |
| 7 | MP0002063_abnormal_learning/memory/cond | 3.42419628 |
| 8 | MP0005423_abnormal_somatic_nervous | 3.33518920 |
| 9 | MP0009046_muscle_twitch | 3.26323596 |
| 10 | MP0002272_abnormal_nervous_system | 3.14387733 |
| 11 | MP0001486_abnormal_startle_reflex | 3.08852792 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.98250640 |
| 13 | MP0002734_abnormal_mechanical_nocicepti | 2.93346237 |
| 14 | MP0002572_abnormal_emotion/affect_behav | 2.84969370 |
| 15 | MP0001501_abnormal_sleep_pattern | 2.67925991 |
| 16 | MP0003329_amyloid_beta_deposits | 2.52989079 |
| 17 | MP0008569_lethality_at_weaning | 2.34950793 |
| 18 | MP0003879_abnormal_hair_cell | 2.30558057 |
| 19 | MP0002735_abnormal_chemical_nociception | 2.19427088 |
| 20 | MP0002736_abnormal_nociception_after | 2.12167938 |
| 21 | MP0001970_abnormal_pain_threshold | 1.93605740 |
| 22 | MP0003787_abnormal_imprinting | 1.85220688 |
| 23 | MP0004811_abnormal_neuron_physiology | 1.76169415 |
| 24 | MP0002733_abnormal_thermal_nociception | 1.73910618 |
| 25 | MP0002067_abnormal_sensory_capabilities | 1.72370135 |
| 26 | MP0009780_abnormal_chondrocyte_physiolo | 1.72065083 |
| 27 | MP0001440_abnormal_grooming_behavior | 1.67356069 |
| 28 | MP0003633_abnormal_nervous_system | 1.67177363 |
| 29 | MP0003690_abnormal_glial_cell | 1.57149304 |
| 30 | MP0000920_abnormal_myelination | 1.55366284 |
| 31 | MP0002557_abnormal_social/conspecific_i | 1.48689740 |
| 32 | MP0002066_abnormal_motor_capabilities/c | 1.48553564 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.44281719 |
| 34 | MP0004924_abnormal_behavior | 1.41030910 |
| 35 | MP0005386_behavior/neurological_phenoty | 1.41030910 |
| 36 | MP0001177_atelectasis | 1.39298981 |
| 37 | MP0000778_abnormal_nervous_system | 1.38926805 |
| 38 | MP0003631_nervous_system_phenotype | 1.36839457 |
| 39 | MP0003123_paternal_imprinting | 1.35063552 |
| 40 | MP0002882_abnormal_neuron_morphology | 1.32588212 |
| 41 | MP0001905_abnormal_dopamine_level | 1.31118439 |
| 42 | MP0000604_amyloidosis | 1.24875057 |
| 43 | MP0000955_abnormal_spinal_cord | 1.24466102 |
| 44 | MP0001502_abnormal_circadian_rhythm | 1.23723796 |
| 45 | MP0004885_abnormal_endolymph | 1.19502488 |
| 46 | MP0006276_abnormal_autonomic_nervous | 1.18399550 |
| 47 | MP0005623_abnormal_meninges_morphology | 1.18059754 |
| 48 | MP0003122_maternal_imprinting | 1.12846882 |
| 49 | MP0002184_abnormal_innervation | 1.11599258 |
| 50 | MP0008877_abnormal_DNA_methylation | 1.09446272 |
| 51 | MP0010386_abnormal_urinary_bladder | 1.07786429 |
| 52 | MP0004742_abnormal_vestibular_system | 1.01546816 |
| 53 | MP0003634_abnormal_glial_cell | 1.01265923 |
| 54 | MP0003075_altered_response_to | 0.99673319 |
| 55 | MP0001963_abnormal_hearing_physiology | 0.98594419 |
| 56 | MP0002638_abnormal_pupillary_reflex | 0.97236890 |
| 57 | MP0002229_neurodegeneration | 0.97100668 |
| 58 | MP0008874_decreased_physiological_sensi | 0.96994983 |
| 59 | MP0001984_abnormal_olfaction | 0.96711937 |
| 60 | MP0002152_abnormal_brain_morphology | 0.95016469 |
| 61 | MP0004147_increased_porphyrin_level | 0.91863209 |
| 62 | MP0001348_abnormal_lacrimal_gland | 0.87982919 |
| 63 | MP0001346_abnormal_lacrimal_gland | 0.83792029 |
| 64 | MP0003632_abnormal_nervous_system | 0.83100416 |
| 65 | MP0003172_abnormal_lysosome_physiology | 0.82832008 |
| 66 | MP0002822_catalepsy | 0.80623241 |
| 67 | MP0001958_emphysema | 0.70843827 |
| 68 | MP0005551_abnormal_eye_electrophysiolog | 0.68792492 |
| 69 | MP0000751_myopathy | 0.66686283 |
| 70 | MP0005535_abnormal_body_temperature | 0.65857820 |
| 71 | MP0001299_abnormal_eye_distance/ | 0.64943794 |
| 72 | MP0002069_abnormal_eating/drinking_beha | 0.62557649 |
| 73 | MP0001485_abnormal_pinna_reflex | 0.61758563 |
| 74 | MP0003137_abnormal_impulse_conducting | 0.60728029 |
| 75 | MP0004130_abnormal_muscle_cell | 0.55220988 |
| 76 | MP0002752_abnormal_somatic_nervous | 0.53140562 |
| 77 | MP0001943_abnormal_respiration | 0.52481653 |
| 78 | MP0003283_abnormal_digestive_organ | 0.51729075 |
| 79 | MP0004085_abnormal_heartbeat | 0.51697953 |
| 80 | MP0005257_abnormal_intraocular_pressure | 0.51475597 |
| 81 | MP0010769_abnormal_survival | 0.50324427 |
| 82 | MP0005499_abnormal_olfactory_system | 0.48937011 |
| 83 | MP0005394_taste/olfaction_phenotype | 0.48937011 |
| 84 | MP0001986_abnormal_taste_sensitivity | 0.48411758 |
| 85 | MP0003956_abnormal_body_size | 0.47880146 |
| 86 | MP0002089_abnormal_postnatal_growth/wei | 0.47798467 |
| 87 | MP0010768_mortality/aging | 0.47422750 |
| 88 | MP0004510_myositis | 0.46452671 |
| 89 | MP0003121_genomic_imprinting | 0.46378438 |
| 90 | MP0003183_abnormal_peptide_metabolism | 0.45822261 |
| 91 | MP0001529_abnormal_vocalization | 0.45360170 |
| 92 | MP0010770_preweaning_lethality | 0.45267298 |
| 93 | MP0002082_postnatal_lethality | 0.45267298 |
| 94 | MP0008872_abnormal_physiological_respon | 0.44774953 |
| 95 | MP0005388_respiratory_system_phenotype | 0.44141468 |
| 96 | MP0002133_abnormal_respiratory_system | 0.44141468 |
| 97 | MP0005166_decreased_susceptibility_to | 0.42627039 |
| 98 | MP0003705_abnormal_hypodermis_morpholog | 0.41393662 |
| 99 | MP0002873_normal_phenotype | 0.39783190 |
| 100 | MP0002090_abnormal_vision | 0.38810540 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 8.56237300 |
| 2 | Focal motor seizures (HP:0011153) | 8.17100807 |
| 3 | Focal seizures (HP:0007359) | 6.61705124 |
| 4 | Febrile seizures (HP:0002373) | 6.14882641 |
| 5 | Atonic seizures (HP:0010819) | 5.92341601 |
| 6 | Action tremor (HP:0002345) | 5.56151044 |
| 7 | Epileptic encephalopathy (HP:0200134) | 5.30206129 |
| 8 | Supranuclear gaze palsy (HP:0000605) | 5.18290638 |
| 9 | Diplopia (HP:0000651) | 5.01886150 |
| 10 | Abnormality of binocular vision (HP:0011514) | 5.01886150 |
| 11 | Ankle clonus (HP:0011448) | 4.61354781 |
| 12 | Generalized tonic-clonic seizures (HP:0002069) | 4.22873300 |
| 13 | Papilledema (HP:0001085) | 4.05508366 |
| 14 | Absence seizures (HP:0002121) | 4.00506241 |
| 15 | Neurofibrillary tangles (HP:0002185) | 3.98829811 |
| 16 | Visual hallucinations (HP:0002367) | 3.94597277 |
| 17 | Torticollis (HP:0000473) | 3.85390145 |
| 18 | Spastic gait (HP:0002064) | 3.85278314 |
| 19 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.79387334 |
| 20 | Dialeptic seizures (HP:0011146) | 3.78299303 |
| 21 | Obstructive sleep apnea (HP:0002870) | 3.75702457 |
| 22 | Dysmetria (HP:0001310) | 3.57989471 |
| 23 | Annular pancreas (HP:0001734) | 3.56819528 |
| 24 | Progressive cerebellar ataxia (HP:0002073) | 3.49742550 |
| 25 | Tetraplegia (HP:0002445) | 3.47248241 |
| 26 | Abnormal eating behavior (HP:0100738) | 3.41884206 |
| 27 | Postural instability (HP:0002172) | 3.41136766 |
| 28 | Mutism (HP:0002300) | 3.34280970 |
| 29 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.33290806 |
| 30 | Neuronal loss in central nervous system (HP:0002529) | 3.30226924 |
| 31 | Truncal ataxia (HP:0002078) | 3.28400640 |
| 32 | Cerebral inclusion bodies (HP:0100314) | 3.28221523 |
| 33 | Focal dystonia (HP:0004373) | 3.23752645 |
| 34 | Intention tremor (HP:0002080) | 3.20926442 |
| 35 | Delusions (HP:0000746) | 3.12140300 |
| 36 | Depression (HP:0000716) | 3.00806815 |
| 37 | Cerebral hypomyelination (HP:0006808) | 2.98877914 |
| 38 | Craniofacial dystonia (HP:0012179) | 2.98329129 |
| 39 | Urinary urgency (HP:0000012) | 2.96494485 |
| 40 | Status epilepticus (HP:0002133) | 2.95579838 |
| 41 | Amblyopia (HP:0000646) | 2.89186442 |
| 42 | Lower limb muscle weakness (HP:0007340) | 2.86695759 |
| 43 | Poor eye contact (HP:0000817) | 2.85707940 |
| 44 | Bradykinesia (HP:0002067) | 2.82629804 |
| 45 | Epileptiform EEG discharges (HP:0011182) | 2.79187602 |
| 46 | Hemiplegia (HP:0002301) | 2.77358490 |
| 47 | Anxiety (HP:0000739) | 2.73230267 |
| 48 | Limb dystonia (HP:0002451) | 2.67683220 |
| 49 | Clonus (HP:0002169) | 2.65548435 |
| 50 | Abnormality of the lower motor neuron (HP:0002366) | 2.62970241 |
| 51 | Akinesia (HP:0002304) | 2.57378588 |
| 52 | Impaired vibratory sensation (HP:0002495) | 2.56023080 |
| 53 | Scanning speech (HP:0002168) | 2.55360029 |
| 54 | Insomnia (HP:0100785) | 2.47505937 |
| 55 | Abnormality of the corticospinal tract (HP:0002492) | 2.46921577 |
| 56 | Apathy (HP:0000741) | 2.41306860 |
| 57 | Dysdiadochokinesis (HP:0002075) | 2.40560044 |
| 58 | Sleep apnea (HP:0010535) | 2.38740305 |
| 59 | Impaired smooth pursuit (HP:0007772) | 2.34029122 |
| 60 | EEG with generalized epileptiform discharges (HP:0011198) | 2.32439033 |
| 61 | Bundle branch block (HP:0011710) | 2.25760196 |
| 62 | Abnormal social behavior (HP:0012433) | 2.24737332 |
| 63 | Impaired social interactions (HP:0000735) | 2.24737332 |
| 64 | Rigidity (HP:0002063) | 2.23319106 |
| 65 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.19295529 |
| 66 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.19295529 |
| 67 | Incomplete penetrance (HP:0003829) | 2.18738099 |
| 68 | Hemiparesis (HP:0001269) | 2.15423746 |
| 69 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.12429279 |
| 70 | Slow saccadic eye movements (HP:0000514) | 2.12182419 |
| 71 | Diminished motivation (HP:0000745) | 2.07775991 |
| 72 | Hypsarrhythmia (HP:0002521) | 2.07767774 |
| 73 | Stereotypic behavior (HP:0000733) | 2.07532039 |
| 74 | Abnormality of saccadic eye movements (HP:0000570) | 2.05522359 |
| 75 | Spastic tetraparesis (HP:0001285) | 2.03051500 |
| 76 | Lower limb amyotrophy (HP:0007210) | 2.02794345 |
| 77 | Rapidly progressive (HP:0003678) | 2.00581511 |
| 78 | Peripheral hypomyelination (HP:0007182) | 1.99860832 |
| 79 | Spinal canal stenosis (HP:0003416) | 1.98762223 |
| 80 | Choreoathetosis (HP:0001266) | 1.98512326 |
| 81 | Upper limb amyotrophy (HP:0009129) | 1.93636671 |
| 82 | Distal upper limb amyotrophy (HP:0007149) | 1.93636671 |
| 83 | Mild short stature (HP:0003502) | 1.92825498 |
| 84 | Lower limb asymmetry (HP:0100559) | 1.91322223 |
| 85 | Gaze-evoked nystagmus (HP:0000640) | 1.89104838 |
| 86 | Hand muscle atrophy (HP:0009130) | 1.88016386 |
| 87 | Heart block (HP:0012722) | 1.85423698 |
| 88 | Memory impairment (HP:0002354) | 1.83686912 |
| 89 | Abnormal atrioventricular conduction (HP:0005150) | 1.78821558 |
| 90 | Aplasia involving bones of the extremities (HP:0009825) | 1.78552654 |
| 91 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.78552654 |
| 92 | Aplasia of the phalanges of the hand (HP:0009802) | 1.78552654 |
| 93 | CNS hypomyelination (HP:0003429) | 1.78075738 |
| 94 | Gait ataxia (HP:0002066) | 1.77998259 |
| 95 | Ventricular fibrillation (HP:0001663) | 1.75733430 |
| 96 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.73421063 |
| 97 | Bronchomalacia (HP:0002780) | 1.71016264 |
| 98 | Absent speech (HP:0001344) | 1.70836854 |
| 99 | Drooling (HP:0002307) | 1.68967127 |
| 100 | Dysmetric saccades (HP:0000641) | 1.68183154 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA4 | 6.95324201 |
| 2 | PAK6 | 4.06312668 |
| 3 | DAPK2 | 4.01562978 |
| 4 | NTRK3 | 3.85837091 |
| 5 | MAP3K9 | 2.73714999 |
| 6 | MARK1 | 2.65214318 |
| 7 | NTRK1 | 2.61893542 |
| 8 | UHMK1 | 2.45700791 |
| 9 | CAMKK1 | 2.36631399 |
| 10 | MINK1 | 2.19125042 |
| 11 | PRKD3 | 2.14925346 |
| 12 | CDK19 | 2.06566804 |
| 13 | RIPK4 | 2.05004508 |
| 14 | LATS2 | 2.02449789 |
| 15 | NTRK2 | 2.00208701 |
| 16 | PLK2 | 1.97314817 |
| 17 | ARAF | 1.96728051 |
| 18 | GRK5 | 1.84736041 |
| 19 | DAPK1 | 1.76398354 |
| 20 | KSR2 | 1.55064864 |
| 21 | MAP3K13 | 1.53349115 |
| 22 | CDK5 | 1.52034767 |
| 23 | CAMK1 | 1.50297753 |
| 24 | MAPK13 | 1.38168832 |
| 25 | CASK | 1.28024293 |
| 26 | PINK1 | 1.26307309 |
| 27 | PRKCH | 1.22343002 |
| 28 | PRKCG | 1.19343547 |
| 29 | BMPR2 | 1.17002354 |
| 30 | CDK15 | 1.14336244 |
| 31 | CDK18 | 1.10728568 |
| 32 | STK38 | 1.05634093 |
| 33 | CDK11A | 1.05476131 |
| 34 | CAMK2B | 1.04917480 |
| 35 | DYRK1A | 1.00032378 |
| 36 | CDK14 | 0.99256823 |
| 37 | CAMKK2 | 0.98898958 |
| 38 | TYRO3 | 0.98114883 |
| 39 | PRPF4B | 0.96707067 |
| 40 | PTK2B | 0.95206956 |
| 41 | RIPK1 | 0.93826526 |
| 42 | MARK2 | 0.92237453 |
| 43 | OXSR1 | 0.91931052 |
| 44 | CAMK2A | 0.91110705 |
| 45 | PAK3 | 0.90962862 |
| 46 | SGK223 | 0.89978574 |
| 47 | SGK494 | 0.89978574 |
| 48 | NEK6 | 0.89789706 |
| 49 | BRSK1 | 0.86396818 |
| 50 | MAPK12 | 0.86251550 |
| 51 | ALK | 0.85354153 |
| 52 | SIK2 | 0.84726628 |
| 53 | STK11 | 0.82752914 |
| 54 | PDK1 | 0.77039734 |
| 55 | BRAF | 0.76405579 |
| 56 | MAP3K11 | 0.76033300 |
| 57 | DAPK3 | 0.75023987 |
| 58 | PHKG2 | 0.71165064 |
| 59 | PHKG1 | 0.71165064 |
| 60 | MAP2K4 | 0.70589884 |
| 61 | PNCK | 0.69730566 |
| 62 | PDPK1 | 0.67288589 |
| 63 | CAMK2G | 0.66666835 |
| 64 | CAMK4 | 0.66061033 |
| 65 | SGK1 | 0.66012342 |
| 66 | LIMK1 | 0.65340135 |
| 67 | MAP3K12 | 0.64873084 |
| 68 | PRKG2 | 0.60070979 |
| 69 | TESK1 | 0.59346492 |
| 70 | SGK2 | 0.58839663 |
| 71 | SGK3 | 0.58037554 |
| 72 | MAPK10 | 0.56833362 |
| 73 | RAF1 | 0.56363248 |
| 74 | MOS | 0.56028042 |
| 75 | KSR1 | 0.55564796 |
| 76 | MAP3K4 | 0.53213212 |
| 77 | PDGFRA | 0.50021185 |
| 78 | SCYL2 | 0.48930914 |
| 79 | RPS6KA3 | 0.48721088 |
| 80 | MAP3K1 | 0.45228293 |
| 81 | CAMK1G | 0.44332655 |
| 82 | PKN1 | 0.42761621 |
| 83 | WNK1 | 0.42634608 |
| 84 | CCNB1 | 0.42264091 |
| 85 | ROCK2 | 0.40542925 |
| 86 | FES | 0.39778273 |
| 87 | PRKCZ | 0.39575819 |
| 88 | FYN | 0.37616457 |
| 89 | CAMK2D | 0.36929211 |
| 90 | MAP2K7 | 0.36517476 |
| 91 | ROCK1 | 0.32380135 |
| 92 | RET | 0.32258487 |
| 93 | JAK1 | 0.32209246 |
| 94 | PRKCA | 0.31625340 |
| 95 | MAP3K2 | 0.30954784 |
| 96 | MAP2K1 | 0.30423052 |
| 97 | FGFR2 | 0.29778705 |
| 98 | MAP2K6 | 0.27845453 |
| 99 | CSNK1G2 | 0.26978024 |
| 100 | MAPK7 | 0.26946512 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 4.19379182 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 4.14713851 |
| 3 | Long-term potentiation_Homo sapiens_hsa04720 | 3.13503049 |
| 4 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.96447911 |
| 5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.71211230 |
| 6 | GABAergic synapse_Homo sapiens_hsa04727 | 2.69768442 |
| 7 | Morphine addiction_Homo sapiens_hsa05032 | 2.55038504 |
| 8 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.53463652 |
| 9 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.52488803 |
| 10 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.50603659 |
| 11 | Insulin secretion_Homo sapiens_hsa04911 | 2.49725180 |
| 12 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.16515885 |
| 13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.15566160 |
| 14 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.12046253 |
| 15 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 2.04564802 |
| 16 | Cocaine addiction_Homo sapiens_hsa05030 | 2.02872509 |
| 17 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.93311542 |
| 18 | Salivary secretion_Homo sapiens_hsa04970 | 1.87475925 |
| 19 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.80260708 |
| 20 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.73703369 |
| 21 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.68696492 |
| 22 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.65828850 |
| 23 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.61515440 |
| 24 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.53598756 |
| 25 | Renin secretion_Homo sapiens_hsa04924 | 1.50440788 |
| 26 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.45838763 |
| 27 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.39133821 |
| 28 | Glioma_Homo sapiens_hsa05214 | 1.35297002 |
| 29 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.35015265 |
| 30 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.34412770 |
| 31 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.27289818 |
| 32 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.22789490 |
| 33 | Melanogenesis_Homo sapiens_hsa04916 | 1.20144662 |
| 34 | Taste transduction_Homo sapiens_hsa04742 | 1.18642724 |
| 35 | Long-term depression_Homo sapiens_hsa04730 | 1.18574618 |
| 36 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.15591420 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.15014229 |
| 38 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.13954883 |
| 39 | Gap junction_Homo sapiens_hsa04540 | 1.11712200 |
| 40 | Olfactory transduction_Homo sapiens_hsa04740 | 1.11359899 |
| 41 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.11160479 |
| 42 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.02494277 |
| 43 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.00600046 |
| 44 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.91518238 |
| 45 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.91470059 |
| 46 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.84301940 |
| 47 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.83912956 |
| 48 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.81516376 |
| 49 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79546723 |
| 50 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.79144209 |
| 51 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.78300419 |
| 52 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.74873191 |
| 53 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74757107 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74733912 |
| 55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.72729282 |
| 56 | Axon guidance_Homo sapiens_hsa04360 | 0.71580538 |
| 57 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.71330986 |
| 58 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.70602856 |
| 59 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.70047827 |
| 60 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.68987406 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.68245596 |
| 62 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.66918613 |
| 63 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.66534891 |
| 64 | Prion diseases_Homo sapiens_hsa05020 | 0.66274951 |
| 65 | Bile secretion_Homo sapiens_hsa04976 | 0.63413787 |
| 66 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.62099580 |
| 67 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.62029532 |
| 68 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61880351 |
| 69 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.60241429 |
| 70 | Phototransduction_Homo sapiens_hsa04744 | 0.58338117 |
| 71 | Endocytosis_Homo sapiens_hsa04144 | 0.57942208 |
| 72 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.56473387 |
| 73 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.54846024 |
| 74 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50255815 |
| 75 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.49015597 |
| 76 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.45255761 |
| 77 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.40887776 |
| 78 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.38579016 |
| 79 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.35087599 |
| 80 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.34701416 |
| 81 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.34243476 |
| 82 | Alcoholism_Homo sapiens_hsa05034 | 0.33828128 |
| 83 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.32933385 |
| 84 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.30111735 |
| 85 | Circadian rhythm_Homo sapiens_hsa04710 | 0.29997519 |
| 86 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29696470 |
| 87 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.27668920 |
| 88 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.27551102 |
| 89 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.26385729 |
| 90 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.25753223 |
| 91 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.22340972 |
| 92 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.21813145 |
| 93 | Tight junction_Homo sapiens_hsa04530 | 0.21153290 |
| 94 | Mineral absorption_Homo sapiens_hsa04978 | 0.19319492 |
| 95 | Alzheimers disease_Homo sapiens_hsa05010 | 0.18813819 |
| 96 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.18494066 |
| 97 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.17475369 |
| 98 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.17296850 |
| 99 | Focal adhesion_Homo sapiens_hsa04510 | 0.17240787 |
| 100 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.16419081 |

