TMEM164

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to peptidoglycan (GO:0032494)4.46811976
2detection of other organism (GO:0098543)4.11879260
3detection of molecule of bacterial origin (GO:0032490)3.91892792
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.91403268
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.91403268
6detection of bacterium (GO:0016045)3.79923530
7detection of external biotic stimulus (GO:0098581)3.70097095
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.52475051
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.52475051
10positive regulation by organism of defense response of other organism involved in symbiotic interact3.52475051
11modulation by symbiont of host immune response (GO:0052553)3.52475051
12positive regulation by symbiont of host defense response (GO:0052509)3.52475051
13modulation by symbiont of host defense response (GO:0052031)3.52475051
14antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.50353001
15regulation of mast cell degranulation (GO:0043304)3.47039889
16neutrophil activation (GO:0042119)3.46029262
17negative regulation of fatty acid transport (GO:2000192)3.37921527
18positive regulation of gamma-delta T cell activation (GO:0046645)3.35574706
19antigen processing and presentation of endogenous antigen (GO:0019883)3.30408239
20positive regulation of histone deacetylation (GO:0031065)3.30118360
21regulation of myeloid leukocyte mediated immunity (GO:0002886)3.29465049
22positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.28391537
23positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.25675376
24granulocyte activation (GO:0036230)3.23755560
25positive regulation of Cdc42 GTPase activity (GO:0043089)3.23686731
26detection of biotic stimulus (GO:0009595)3.22218922
27positive regulation of cellular amide metabolic process (GO:0034250)3.14972258
28mannose metabolic process (GO:0006013)3.13637247
29negative regulation of interleukin-12 production (GO:0032695)3.13607703
30regulation of mast cell activation involved in immune response (GO:0033006)3.10863617
31macrophage activation (GO:0042116)3.07826567
32lipopolysaccharide-mediated signaling pathway (GO:0031663)3.05732512
33negative regulation of phagocytosis (GO:0050765)2.96456128
34Golgi transport vesicle coating (GO:0048200)2.96290845
35COPI coating of Golgi vesicle (GO:0048205)2.96290845
36definitive hemopoiesis (GO:0060216)2.95926863
37regulation of regulated secretory pathway (GO:1903305)2.93298703
38surfactant homeostasis (GO:0043129)2.90760294
39germinal center formation (GO:0002467)2.89558300
40negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.85721438
41germ cell migration (GO:0008354)2.84878936
42regulation of interferon-beta biosynthetic process (GO:0045357)2.84247199
43negative regulation of lymphocyte mediated immunity (GO:0002707)2.84141496
44positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.83856136
45antigen processing and presentation via MHC class Ib (GO:0002475)2.82607219
46regulation of gamma-delta T cell differentiation (GO:0045586)2.82390872
47myeloid cell activation involved in immune response (GO:0002275)2.82335442
48leukocyte aggregation (GO:0070486)2.76040767
49embryonic process involved in female pregnancy (GO:0060136)2.75920126
50positive regulation of mast cell activation (GO:0033005)2.74924072
51apoptotic cell clearance (GO:0043277)2.72499237
52leukocyte migration involved in inflammatory response (GO:0002523)2.72417907
53microglial cell activation (GO:0001774)2.72178550
54regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.68249714
55RNA stabilization (GO:0043489)2.67100245
56mRNA stabilization (GO:0048255)2.67100245
57positive regulation of regulated secretory pathway (GO:1903307)2.66803624
58positive regulation of leukocyte degranulation (GO:0043302)2.66478355
59pinocytosis (GO:0006907)2.63982849
60negative regulation of granulocyte differentiation (GO:0030853)2.63536871
61epithelial cell differentiation involved in prostate gland development (GO:0060742)2.63131582
62negative regulation of T cell mediated immunity (GO:0002710)2.62535625
63B cell receptor signaling pathway (GO:0050853)2.62332627
64positive regulation of B cell differentiation (GO:0045579)2.61480106
65negative regulation of leukocyte mediated immunity (GO:0002704)2.61285096
66regulation of gamma-delta T cell activation (GO:0046643)2.60921044
67regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.60187709
68sequestering of metal ion (GO:0051238)2.59069139
69macrophage activation involved in immune response (GO:0002281)2.58473553
70cellular response to thyroid hormone stimulus (GO:0097067)2.57983244
71response to interleukin-15 (GO:0070672)2.57591009
72regulation of necroptotic process (GO:0060544)2.56573791
733-UTR-mediated mRNA stabilization (GO:0070935)2.54371279
74cell adhesion mediated by integrin (GO:0033627)2.54200448
75glucocorticoid receptor signaling pathway (GO:0042921)2.54144158
76neutrophil mediated immunity (GO:0002446)2.54080593
77regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.53420512
78positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.52591361
79neutrophil activation involved in immune response (GO:0002283)2.52243961
80regulation of mast cell activation (GO:0033003)2.50890984
81endothelial tube morphogenesis (GO:0061154)2.49520890
82morphogenesis of an endothelium (GO:0003159)2.49520890
83positive regulation of receptor recycling (GO:0001921)2.49337497
84regulation of T-helper 2 cell differentiation (GO:0045628)2.48802838
85vascular endothelial growth factor signaling pathway (GO:0038084)2.48403386
86response to host (GO:0075136)2.47506962
87response to host defenses (GO:0052200)2.47506962
88response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.47506962
89T cell apoptotic process (GO:0070231)2.47124774
90Arp2/3 complex-mediated actin nucleation (GO:0034314)2.43774643
91positive regulation of mast cell degranulation (GO:0043306)2.41942259
92positive regulation of mast cell activation involved in immune response (GO:0033008)2.41942259
93leukocyte degranulation (GO:0043299)2.41340925
94negative regulation of toll-like receptor signaling pathway (GO:0034122)2.41223941
95regulation of B cell receptor signaling pathway (GO:0050855)2.39301300
96positive regulation of protein deacetylation (GO:0090312)2.38767412
97regulation of platelet aggregation (GO:0090330)2.38208057
98JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.38173607
99response to host immune response (GO:0052572)2.37770641
100response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.37770641
101positive regulation of tumor necrosis factor production (GO:0032760)2.37380646
102leukocyte cell-cell adhesion (GO:0007159)2.36936480
103endodermal cell differentiation (GO:0035987)2.36738716
104amyloid precursor protein catabolic process (GO:0042987)2.36358146
105regulation of interleukin-12 biosynthetic process (GO:0045075)2.36303809
106NADPH regeneration (GO:0006740)2.35398180
107negative regulation of erythrocyte differentiation (GO:0045647)2.34959195
108axon extension involved in axon guidance (GO:0048846)2.34813433
109neuron projection extension involved in neuron projection guidance (GO:1902284)2.34813433
110cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.32730156
111actin filament polymerization (GO:0030041)2.32534487
112hepatocyte apoptotic process (GO:0097284)2.31908874
113glycosphingolipid catabolic process (GO:0046479)2.31589919
114positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.30859027
115coronary vasculature morphogenesis (GO:0060977)2.30851499
116regulation of macrophage cytokine production (GO:0010935)2.28908220
117regulation of erythrocyte differentiation (GO:0045646)2.28718003
118DNA unwinding involved in DNA replication (GO:0006268)2.25840557
119corticosteroid receptor signaling pathway (GO:0031958)2.25576867
120cellular extravasation (GO:0045123)2.23910196
121immunoglobulin mediated immune response (GO:0016064)2.21574353
122positive regulation of nuclease activity (GO:0032075)2.19364290
123pentose-phosphate shunt (GO:0006098)2.18639513
124substrate-dependent cell migration (GO:0006929)2.17504157
125activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.16966096
126negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.16767202
127negative regulation of cell killing (GO:0031342)2.16767202
128response to muramyl dipeptide (GO:0032495)2.15981955
129positive regulation of blood vessel endothelial cell migration (GO:0043536)2.15770606
130maternal placenta development (GO:0001893)2.13254977
131receptor catabolic process (GO:0032801)2.12522921
132megakaryocyte development (GO:0035855)2.12486440
133dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.11974638
134peptidyl-lysine dimethylation (GO:0018027)2.11062923
135response to fluid shear stress (GO:0034405)2.10928022
136negative regulation of stress fiber assembly (GO:0051497)2.08631777
137positive regulation of interferon-alpha production (GO:0032727)2.08056669
138integrin-mediated signaling pathway (GO:0007229)2.07558480
139regulation of B cell differentiation (GO:0045577)2.06903085
140natural killer cell differentiation (GO:0001779)2.06857946
141response to laminar fluid shear stress (GO:0034616)2.06713644
142regulation of leukocyte degranulation (GO:0043300)2.06221837
143positive regulation of cell adhesion mediated by integrin (GO:0033630)2.06049062
144positive thymic T cell selection (GO:0045059)2.05526777
145protein localization to endosome (GO:0036010)2.05504872
146insulin-like growth factor receptor signaling pathway (GO:0048009)2.05177787
147cortical actin cytoskeleton organization (GO:0030866)2.05138600
148mitotic chromosome condensation (GO:0007076)2.03955447
149cellular response to zinc ion (GO:0071294)2.02473557
150respiratory burst (GO:0045730)2.02191134
151epithelial cell-cell adhesion (GO:0090136)2.02072064
152positive regulation of p38MAPK cascade (GO:1900745)2.01654722
153production of molecular mediator involved in inflammatory response (GO:0002532)2.00987637

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.69581172
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.54941857
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.68301442
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.36281158
5MYC_22102868_ChIP-Seq_BL_Human3.04491642
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.02097508
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.96009860
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.68081163
9VDR_21846776_ChIP-Seq_THP-1_Human2.65306168
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.57508904
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.55713804
12MYB_21317192_ChIP-Seq_ERMYB_Mouse2.47451445
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.29185287
14IRF8_21731497_ChIP-ChIP_J774_Mouse2.28005567
15* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.27205754
16FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.25480084
17SCL_19346495_ChIP-Seq_HPC-7_Human2.24761208
18* TCF7_22412390_ChIP-Seq_EML_Mouse2.21782209
19VDR_24763502_ChIP-Seq_THP-1_Human2.08084447
20BRD4_27068464_Chip-Seq_AML-cells_Mouse2.07406290
21ELK3_25401928_ChIP-Seq_HUVEC_Human2.03698914
22ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.97206260
23IRF8_27001747_Chip-Seq_BMDM_Mouse1.96586581
24MAF_26560356_Chip-Seq_TH1_Human1.93602623
25UTX_26944678_Chip-Seq_JUKART_Human1.87218848
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.82637954
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.82207821
28KDM2B_26808549_Chip-Seq_DND41_Human1.81672460
29ESR2_21235772_ChIP-Seq_MCF-7_Human1.80900393
30KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.79225599
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.79160942
32THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.78998142
33VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77938367
34MYB_26560356_Chip-Seq_TH2_Human1.75408266
35* SPI1_23127762_ChIP-Seq_K562_Human1.74115945
36CLOCK_20551151_ChIP-Seq_293T_Human1.71392688
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.67246374
38RUNX1_22412390_ChIP-Seq_EML_Mouse1.67157875
39KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.66322021
40STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.63878969
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.60259979
42STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.60019369
43SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.55797445
44RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.52592840
45* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.51863006
46* SPI1_23547873_ChIP-Seq_NB4_Human1.50772682
47HIF1A_21447827_ChIP-Seq_MCF-7_Human1.50327556
48RARG_19884340_ChIP-ChIP_MEFs_Mouse1.48538389
49E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.47302922
50FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.46777938
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.45823326
52IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.45502151
53MYB_26560356_Chip-Seq_TH1_Human1.45309292
54IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.44646065
55EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.44280520
56TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.44072553
57* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.43106012
58ESR1_20079471_ChIP-ChIP_T-47D_Human1.42784241
59RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.38863887
60KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.38777420
61TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38702541
62MAF_26560356_Chip-Seq_TH2_Human1.36740671
63STAT4_19710469_ChIP-ChIP_TH1__Mouse1.36133937
64Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.34870027
65RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.34204036
66KDM2B_26808549_Chip-Seq_K562_Human1.32398238
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.30140853
68RACK7_27058665_Chip-Seq_MCF-7_Human1.30083369
69P300_27058665_Chip-Seq_ZR-75-30cells_Human1.28590679
70RUNX_20019798_ChIP-Seq_JUKART_Human1.28337893
71SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.28281381
72NCOR1_26117541_ChIP-Seq_K562_Human1.26261192
73ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.24922212
74AR_21909140_ChIP-Seq_LNCAP_Human1.24767720
75GATA1_22025678_ChIP-Seq_K562_Human1.24680103
76CTCF_27219007_Chip-Seq_ERYTHROID_Human1.21906552
77SOX2_27498859_Chip-Seq_STOMACH_Mouse1.21830433
78FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.21653594
79TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19552677
80FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.17910489
81ATF3_27146783_Chip-Seq_COLON_Human1.16423477
82* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.16270079
83CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16145970
84E2F4_17652178_ChIP-ChIP_JURKAT_Human1.15985199
85KDM2B_26808549_Chip-Seq_JURKAT_Human1.15787454
86TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.14764350
87FOXO3_23340844_ChIP-Seq_DLD1_Human1.14635144
88SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.13887043
89SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.13887043
90GATA6_25053715_ChIP-Seq_YYC3_Human1.12872833
91LXR_22292898_ChIP-Seq_THP-1_Human1.12428791
92PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12303601
93LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.12063632
94PU_27001747_Chip-Seq_BMDM_Mouse1.11919530
95GATA2_22383799_ChIP-Seq_G1ME_Mouse1.10498363
96CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09574515
97ESR1_21235772_ChIP-Seq_MCF-7_Human1.09555412
98GATA1_19941826_ChIP-Seq_K562_Human1.08798975
99PPARA_22158963_ChIP-Seq_LIVER_Mouse1.08607833
100GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08423448
101CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.08106971
102PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07924224
103E2F1_21310950_ChIP-Seq_MCF-7_Human1.07651759
104VDR_24787735_ChIP-Seq_THP-1_Human1.07603365
105SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07250968
106DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.07218525
107GATA2_21666600_ChIP-Seq_HMVEC_Human1.06461429
108TRIM28_21343339_ChIP-Seq_HEK293_Human1.05770493
109GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05558586
110EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.05203838
111RXR_22158963_ChIP-Seq_LIVER_Mouse1.05132200
112GATA1_19941827_ChIP-Seq_MEL_Mouse1.03821648
113GATA3_27048872_Chip-Seq_THYMUS_Human1.02810064
114SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01788731
115SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99246798
116GATA2_19941826_ChIP-Seq_K562_Human0.98588038
117MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.98536791
118RUNX1_27514584_Chip-Seq_MCF-7_Human0.98105423
119* TBX20_22080862_ChIP-Seq_HEART_Mouse0.97116949
120* TBX20_22328084_ChIP-Seq_HEART_Mouse0.97116949
121GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96513434
122ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.96455643
123FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.95558208
124UBF1/2_26484160_Chip-Seq_HMECs_Human0.95270232

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003191_abnormal_cellular_cholesterol3.02097751
2MP0005451_abnormal_body_composition3.01414921
3MP0003300_gastrointestinal_ulcer2.80902810
4MP0003705_abnormal_hypodermis_morpholog2.65846603
5MP0006054_spinal_hemorrhage2.60972332
6MP0003303_peritoneal_inflammation2.60959459
7MP0009278_abnormal_bone_marrow2.47430453
8MP0010352_gastrointestinal_tract_polyps2.36252741
9MP0008260_abnormal_autophagy2.29808624
10MP0001958_emphysema2.17138204
11MP0003566_abnormal_cell_adhesion2.13175508
12MP0004808_abnormal_hematopoietic_stem2.09323235
13MP0008438_abnormal_cutaneous_collagen2.01222009
14MP0003436_decreased_susceptibility_to1.99977121
15MP0005076_abnormal_cell_differentiation1.98920206
16MP0004782_abnormal_surfactant_physiolog1.91467593
17MP0002396_abnormal_hematopoietic_system1.80336751
18MP0002877_abnormal_melanocyte_morpholog1.77412341
19MP0003279_aneurysm1.70665624
20MP0005409_darkened_coat_color1.69928242
21MP0004947_skin_inflammation1.69465994
22MP0010234_abnormal_vibrissa_follicle1.66073895
23MP0002166_altered_tumor_susceptibility1.65211402
24MP0005058_abnormal_lysosome_morphology1.64661849
25MP0000569_abnormal_digit_pigmentation1.63851746
26MP0005464_abnormal_platelet_physiology1.62597499
27MP0001835_abnormal_antigen_presentation1.60072839
28MP0000465_gastrointestinal_hemorrhage1.59497279
29MP0004264_abnormal_extraembryonic_tissu1.59278335
30MP0009840_abnormal_foam_cell1.59210456
31MP0004381_abnormal_hair_follicle1.58224055
32MP0001545_abnormal_hematopoietic_system1.57684054
33MP0005397_hematopoietic_system_phenotyp1.57684054
34MP0010307_abnormal_tumor_latency1.52705868
35MP0006082_CNS_inflammation1.51937178
36MP0000685_abnormal_immune_system1.51723213
37MP0008004_abnormal_stomach_pH1.46915860
38MP0000537_abnormal_urethra_morphology1.40883134
39MP0002419_abnormal_innate_immunity1.40175675
40MP0000490_abnormal_crypts_of1.39958347
41MP0001873_stomach_inflammation1.39605390
42MP0010368_abnormal_lymphatic_system1.37939928
43MP0003656_abnormal_erythrocyte_physiolo1.34514075
44MP0005666_abnormal_adipose_tissue1.33859555
45MP0002452_abnormal_antigen_presenting1.33091203
46MP0005275_abnormal_skin_tensile1.32724653
47MP0002132_abnormal_respiratory_system1.32229393
48MP0001879_abnormal_lymphatic_vessel1.29340299
49MP0010155_abnormal_intestine_physiology1.28993794
50MP0002796_impaired_skin_barrier1.28235420
51MP0002405_respiratory_system_inflammati1.27987684
52MP0002006_tumorigenesis1.27282693
53MP0001533_abnormal_skeleton_physiology1.25227774
54MP0005025_abnormal_response_to1.22851439
55MP0005023_abnormal_wound_healing1.21430040
56MP0004510_myositis1.19815881
57MP0002420_abnormal_adaptive_immunity1.18812331
58MP0001800_abnormal_humoral_immune1.18667252
59MP0001819_abnormal_immune_cell1.18607006
60MP0005000_abnormal_immune_tolerance1.18370474
61MP0003448_altered_tumor_morphology1.17509837
62MP0000767_abnormal_smooth_muscle1.17378555
63MP0001849_ear_inflammation1.16896969
64MP0002398_abnormal_bone_marrow1.15936517
65MP0005387_immune_system_phenotype1.15828226
66MP0001790_abnormal_immune_system1.15828226
67MP0004883_abnormal_blood_vessel1.14300402
68MP0003075_altered_response_to1.11436871
69MP0000858_altered_metastatic_potential1.10927704
70MP0003172_abnormal_lysosome_physiology1.10869995
71MP0003828_pulmonary_edema1.10501781
72MP0000343_altered_response_to1.09833644
73MP0000733_abnormal_muscle_development1.09754227
74MP0009785_altered_susceptibility_to1.08667779
75MP0004130_abnormal_muscle_cell1.04070957
76MP0002723_abnormal_immune_serum1.03680073
77MP0005083_abnormal_biliary_tract1.02316131
78MP0002009_preneoplasia1.02233137
79MP0008469_abnormal_protein_level1.01712126
80MP0004084_abnormal_cardiac_muscle0.99061662
81MP0001851_eye_inflammation0.98691342
82MP0003567_abnormal_fetal_cardiomyocyte0.98117750
83MP0003183_abnormal_peptide_metabolism0.97982480
84MP0009115_abnormal_fat_cell0.96211060
85MP0002722_abnormal_immune_system0.95734408
86MP0000716_abnormal_immune_system0.95317072
87MP0002933_joint_inflammation0.95009891
88MP0005164_abnormal_response_to0.93757588
89MP0010630_abnormal_cardiac_muscle0.93521792
90MP0002925_abnormal_cardiovascular_devel0.93015252
91MP0003091_abnormal_cell_migration0.92578220
92MP0000689_abnormal_spleen_morphology0.92107457
93MP0001845_abnormal_inflammatory_respons0.91889926
94MP0004185_abnormal_adipocyte_glucose0.90656360
95MP0002429_abnormal_blood_cell0.90143257
96MP0004233_abnormal_muscle_weight0.89104378
97MP0005375_adipose_tissue_phenotype0.89021028
98MP0002971_abnormal_brown_adipose0.88088711
99MP0003329_amyloid_beta_deposits0.87757846
100MP0003866_abnormal_defecation0.87359513
101MP0004272_abnormal_basement_membrane0.87081388
102MP0000604_amyloidosis0.86929226
103MP0002148_abnormal_hypersensitivity_rea0.86449106
104MP0003763_abnormal_thymus_physiology0.86295174
105MP0005248_abnormal_Harderian_gland0.85929124
106MP0004858_abnormal_nervous_system0.85067005
107MP0003724_increased_susceptibility_to0.84319019
108MP0002060_abnormal_skin_morphology0.83396978
109MP0003123_paternal_imprinting0.83368665
110MP0001915_intracranial_hemorrhage0.83174129
111MP0000703_abnormal_thymus_morphology0.82469545
112MP0004197_abnormal_fetal_growth/weight/0.82205793
113MP0002998_abnormal_bone_remodeling0.81871471
114MP0009333_abnormal_splenocyte_physiolog0.81803393
115MP0009053_abnormal_anal_canal0.80779189
116MP0003221_abnormal_cardiomyocyte_apopto0.79980913
117MP0001853_heart_inflammation0.79783036
118MP0005310_abnormal_salivary_gland0.79709220
119MP0002086_abnormal_extraembryonic_tissu0.79095595
120MP0003115_abnormal_respiratory_system0.78095716
121MP0005167_abnormal_blood-brain_barrier0.77353179
122MP0005390_skeleton_phenotype0.77280029
123MP0005671_abnormal_response_to0.77077576
124MP0009931_abnormal_skin_appearance0.77025603
125MP0009764_decreased_sensitivity_to0.76914680
126MP0005166_decreased_susceptibility_to0.76532793
127MP0001614_abnormal_blood_vessel0.76360738
128MP0000609_abnormal_liver_physiology0.76207541
129MP0001175_abnormal_lung_morphology0.76199974
130MP0002128_abnormal_blood_circulation0.75902790
131MP0003453_abnormal_keratinocyte_physiol0.75795228
132MP0003690_abnormal_glial_cell0.74443929
133MP0003795_abnormal_bone_structure0.73140723
134MP0002088_abnormal_embryonic_growth/wei0.71098657
135MP0010030_abnormal_orbit_morphology0.70723952

Predicted human phenotypes

RankGene SetZ-score
1Interstitial pulmonary disease (HP:0006530)4.01075088
2Eczematoid dermatitis (HP:0000976)3.65799356
3Recurrent abscess formation (HP:0002722)3.57095225
4Orchitis (HP:0100796)3.31550876
5Cerebral aneurysm (HP:0004944)3.24724668
6Recurrent bacterial skin infections (HP:0005406)3.07673753
7Chronic obstructive pulmonary disease (HP:0006510)2.95368214
8Obstructive lung disease (HP:0006536)2.95368214
9Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.85475119
10Short 4th metacarpal (HP:0010044)2.85475119
11Subacute progressive viral hepatitis (HP:0006572)2.77293770
12Hematochezia (HP:0002573)2.75571415
13Optic neuritis (HP:0100653)2.69539420
14Retrobulbar optic neuritis (HP:0100654)2.69539420
15Gastrointestinal infarctions (HP:0005244)2.69078898
16Hyperacusis (HP:0010780)2.67187867
17Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.66327456
18Aortic aneurysm (HP:0004942)2.62001352
19Recurrent skin infections (HP:0001581)2.60397375
20Ankle contracture (HP:0006466)2.59119001
21Gingival bleeding (HP:0000225)2.57911712
22Epistaxis (HP:0000421)2.55989530
23Increased cerebral lipofuscin (HP:0011813)2.53824546
24Cellulitis (HP:0100658)2.53232215
25Polycythemia (HP:0001901)2.51454443
26Protrusio acetabuli (HP:0003179)2.51108244
27Urticaria (HP:0001025)2.47288640
28Ulnar bowing (HP:0003031)2.38403335
29Asymmetry of the thorax (HP:0001555)2.37360344
30Centrally nucleated skeletal muscle fibers (HP:0003687)2.36976517
31Loss of speech (HP:0002371)2.35423816
32Osteolytic defects of the hand bones (HP:0009699)2.33802944
33Osteolytic defects of the phalanges of the hand (HP:0009771)2.33802944
34Amyloidosis (HP:0011034)2.32963073
35Chronic otitis media (HP:0000389)2.32098903
36Meningitis (HP:0001287)2.30301717
37Abnormality of glycolipid metabolism (HP:0010969)2.30113614
38Abnormality of liposaccharide metabolism (HP:0010968)2.30113614
39Abnormality of glycosphingolipid metabolism (HP:0004343)2.30113614
40Distal lower limb muscle weakness (HP:0009053)2.29521830
41Gastrointestinal inflammation (HP:0004386)2.28993133
42Increased density of long bones (HP:0006392)2.25628553
43Shallow orbits (HP:0000586)2.23188931
44Inflammation of the large intestine (HP:0002037)2.22666037
45Purpura (HP:0000979)2.19979639
46Thin bony cortex (HP:0002753)2.18579796
47Aortic dissection (HP:0002647)2.17812100
48Recurrent viral infections (HP:0004429)2.17726857
49Periodontitis (HP:0000704)2.17049352
50Stomatitis (HP:0010280)2.15687922
51Colitis (HP:0002583)2.14336817
52Recurrent fungal infections (HP:0002841)2.13537050
53Asymmetric septal hypertrophy (HP:0001670)2.12501567
54Enlarged penis (HP:0000040)2.11472146
55Renal duplication (HP:0000075)2.11084490
56Flat acetabular roof (HP:0003180)2.08723380
57Abnormality of the 4th metacarpal (HP:0010012)2.08295409
58Long toe (HP:0010511)2.08109136
59Spontaneous hematomas (HP:0007420)2.07783890
60Bicuspid aortic valve (HP:0001647)2.07460695
61Metaphyseal cupping (HP:0003021)2.07406486
62Abnormality of the fingertips (HP:0001211)2.06558170
63Fatigue (HP:0012378)2.06511814
64Mitral valve prolapse (HP:0001634)2.06497295
65Dilatation of the ascending aorta (HP:0005111)2.05918784
66Hepatosplenomegaly (HP:0001433)2.05011658
67Keratoconjunctivitis sicca (HP:0001097)2.04920177
68Cervical subluxation (HP:0003308)2.03600707
69Autoimmune thrombocytopenia (HP:0001973)2.03334403
70Episodic fever (HP:0001954)2.02150171
71Broad metatarsal (HP:0001783)2.02064178
72Encephalitis (HP:0002383)2.00755856
73Increased neuronal autofluorescent lipopigment (HP:0002074)2.00296727
74Distal lower limb amyotrophy (HP:0008944)2.00231992
75Chronic mucocutaneous candidiasis (HP:0002728)1.99948740
76Recurrent cutaneous fungal infections (HP:0011370)1.99948740
77Disinhibition (HP:0000734)1.98005398
78Abnormal delayed hypersensitivity skin test (HP:0002963)1.97892780
79Viral hepatitis (HP:0006562)1.95903601
80Recurrent gram-negative bacterial infections (HP:0005420)1.95800013
81Thrombocytosis (HP:0001894)1.95775648
82Abnormality of macrophages (HP:0004311)1.95231488
83Slow saccadic eye movements (HP:0000514)1.94652095
84Aneurysm (HP:0002617)1.93453998
85Macroorchidism (HP:0000053)1.93137831
86Increased connective tissue (HP:0009025)1.93098836
87Increased mean platelet volume (HP:0011877)1.92847747
88Segmental peripheral demyelination/remyelination (HP:0003481)1.92472240
89Vasculitis (HP:0002633)1.90651025
90Increased serum ferritin (HP:0003281)1.90458526
91Persistence of primary teeth (HP:0006335)1.90164853
92Malnutrition (HP:0004395)1.87989139
93Gingivitis (HP:0000230)1.87772785
94Bladder diverticulum (HP:0000015)1.85789294
95Abnormality of polysaccharide metabolism (HP:0011012)1.85607179
96Abnormality of glycosaminoglycan metabolism (HP:0004371)1.85607179
97Abnormality of mucopolysaccharide metabolism (HP:0011020)1.85607179
98Difficulty running (HP:0009046)1.85464604
99Osteomyelitis (HP:0002754)1.84895087
100Hallux valgus (HP:0001822)1.84447565
101Rectal prolapse (HP:0002035)1.83977100
102Spondylolisthesis (HP:0003302)1.83491420
103Deviation of the hallux (HP:0010051)1.82816069
104Micronodular cirrhosis (HP:0001413)1.82721147
105Radial bowing (HP:0002986)1.82255449
106Hypertriglyceridemia (HP:0002155)1.81731330
107Petechiae (HP:0000967)1.80409069
108Lymphangioma (HP:0100764)1.80383980
109Myocardial infarction (HP:0001658)1.80218744
110Increased IgE level (HP:0003212)1.79875543
111Abnormality of skeletal muscle fiber size (HP:0012084)1.78266799
112Broad palm (HP:0001169)1.78214792
113Spinal cord lesions (HP:0100561)1.77857388
114Syringomyelia (HP:0003396)1.77857388
115Myositis (HP:0100614)1.77541673
116Hyporeflexia of lower limbs (HP:0002600)1.77260794
117Atrophic scars (HP:0001075)1.76822971
118Premature rupture of membranes (HP:0001788)1.76601120
119Pustule (HP:0200039)1.75166497
120Menorrhagia (HP:0000132)1.74644803
121Keratoconjunctivitis (HP:0001096)1.72227328
122Dysostosis multiplex (HP:0000943)1.72034311
123Broad face (HP:0000283)1.71880436
124Arterial tortuosity (HP:0005116)1.71516429
125Prolonged bleeding time (HP:0003010)1.71089166
126Increased variability in muscle fiber diameter (HP:0003557)1.70628036
127Exercise-induced myalgia (HP:0003738)1.70527379
128Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.69741211
129Peritonitis (HP:0002586)1.68973663
130High pitched voice (HP:0001620)1.68757125
131Arterial thrombosis (HP:0004420)1.68743347
132Polygenic inheritance (HP:0010982)1.68663550
133Abnormality of iron homeostasis (HP:0011031)1.68564176
134Exostoses (HP:0100777)1.68481666
135Bowing of the arm (HP:0006488)1.67908152
136Bowed forearm bones (HP:0003956)1.67908152
137Elfin facies (HP:0004428)1.67857315
138Bowel diverticulosis (HP:0005222)1.67475810
139Hemorrhage of the eye (HP:0011885)1.67339369
140Chest pain (HP:0100749)1.67242390
141Striae distensae (HP:0001065)1.67197892
142Hemoptysis (HP:0002105)1.66475128
143Urinary glycosaminoglycan excretion (HP:0003541)1.66173657
144Mucopolysacchariduria (HP:0008155)1.66173657
145Mediastinal lymphadenopathy (HP:0100721)1.65188218
146Abnormal platelet volume (HP:0011876)1.65153675
147Cutaneous melanoma (HP:0012056)1.64511493
148Elevated erythrocyte sedimentation rate (HP:0003565)1.62861198
149Camptodactyly of toe (HP:0001836)1.61134835
150Disproportionate tall stature (HP:0001519)1.60736014
151Vascular tortuosity (HP:0004948)1.60268607
152Abnormality of the thoracic spine (HP:0100711)1.59653527
153Renovascular hypertension (HP:0100817)1.59169754
154Vacuolated lymphocytes (HP:0001922)1.58796678
155Abnormal platelet function (HP:0011869)1.56919636
156Impaired platelet aggregation (HP:0003540)1.56919636
157Verrucae (HP:0200043)1.55582695
158Papilloma (HP:0012740)1.55582695
159Milia (HP:0001056)1.55547794
160Subaortic stenosis (HP:0001682)1.55196324

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.94021133
2PKN24.36871755
3RIPK43.90728963
4EEF2K3.52590098
5PRPF4B3.39192536
6MAP3K103.00981285
7TTN2.38550135
8PTK62.33354030
9ERN12.27678707
10IRAK42.20578959
11LRRK22.06248620
12RIPK11.99009134
13SMG11.96489442
14STK101.94825112
15TGFBR21.91222877
16KSR21.70622217
17MAP4K11.69280033
18ZAP701.65947185
19IRAK31.65666253
20MAP2K31.58399652
21FLT31.54690767
22PAK41.52323004
23PDGFRA1.52071793
24SCYL21.50695027
25KIT1.49489009
26MAP3K11.44294978
27JAK31.41242946
28TGFBR11.36453498
29MAP3K61.33119541
30BTK1.31940371
31LATS11.30996295
32MAP3K141.29674720
33ICK1.28610562
34CDK61.28467899
35TYK21.26808696
36SIK11.25694477
37CDK121.22618295
38TNK21.22233793
39TRPM71.21087541
40TBK11.20358432
41YES11.18481982
42MAP3K131.16437994
43PDPK11.14372470
44ILK1.11967015
45IRAK21.11544425
46EPHB11.09998663
47STK241.09135574
48MARK21.08241230
49TAOK21.08156378
50PDGFRB1.07707339
51CAMK1D1.05434325
52NEK21.05182873
53BLK1.04515572
54RPS6KA41.03242362
55FGFR31.03080040
56MAP3K111.01347340
57IRAK11.00617881
58SIK31.00442796
59TAOK30.98555641
60JAK10.98302800
61RPS6KB20.96961511
62FGR0.94775510
63CSF1R0.94174638
64STK30.94103291
65PDK10.92824830
66STK40.91959009
67PASK0.91112802
68RET0.88261030
69DMPK0.84538503
70HCK0.84032391
71MAP3K80.83725539
72TIE10.83500436
73MAP3K30.81262241
74JAK20.79339242
75NEK90.78858570
76TESK20.78699560
77BMX0.78495819
78LMTK20.78348068
79KDR0.77848362
80ITK0.76936370
81MATK0.75458883
82HIPK20.75403037
83TEC0.73641671
84GRK60.73246718
85RPS6KA20.72668344
86CDC42BPA0.72317739
87TESK10.72166800
88MAPK120.70807567
89TAOK10.70411078
90PRKD20.69863556
91CAMK1G0.67941899
92CDK40.67432910
93ALK0.66515212
94SGK30.65814834
95FGFR40.65176414
96SYK0.64697396
97SIK20.64461518
98PIM10.64052997
99PAK20.63759239
100DDR20.63756211
101MTOR0.63746497
102BMPR20.62084402
103MAP2K20.61675128
104CHUK0.61526083
105CDC70.61081462
106NME20.60770792
107CLK10.60038359
108EPHA30.59889788
109PTK20.59096662
110MAP3K70.58873496
111PRKCH0.58667559
112LCK0.54509545
113KSR10.53764671
114EGFR0.52949275
115CSK0.52041827
116FGFR10.51678616
117RPS6KC10.51333021
118RPS6KL10.51333021
119RPS6KA60.50781969
120MAP2K40.50299324
121RAF10.48983028
122BRSK20.44988412
123MARK30.43259624
124CDK90.43220385
125FES0.41252317
126LYN0.40365631
127PRKG20.39782333
128MAP3K20.38696431
129RPS6KA10.38481714
130EPHB20.37893613
131IKBKE0.37441430
132MAPKAPK20.37156360
133MAP2K10.36864225
134MAP3K50.36559373
135MAPKAPK30.36346243
136DYRK1B0.36330458
137FYN0.35219761

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.28308994
2Chronic myeloid leukemia_Homo sapiens_hsa052202.05089681
3Osteoclast differentiation_Homo sapiens_hsa043801.83979949
4Leukocyte transendothelial migration_Homo sapiens_hsa046701.66826749
5Small cell lung cancer_Homo sapiens_hsa052221.64991516
6AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.64142941
7Toxoplasmosis_Homo sapiens_hsa051451.61582414
8B cell receptor signaling pathway_Homo sapiens_hsa046621.61523791
9Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.56764183
10Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.55589313
11Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.55086446
12Viral myocarditis_Homo sapiens_hsa054161.49434806
13Platelet activation_Homo sapiens_hsa046111.48445675
14Pancreatic cancer_Homo sapiens_hsa052121.48026878
15Focal adhesion_Homo sapiens_hsa045101.38587727
16Proteoglycans in cancer_Homo sapiens_hsa052051.38577795
17Lysosome_Homo sapiens_hsa041421.34964110
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.33930474
19Glycosaminoglycan degradation_Homo sapiens_hsa005311.33353231
20Acute myeloid leukemia_Homo sapiens_hsa052211.30495961
21Adherens junction_Homo sapiens_hsa045201.30216910
22Antigen processing and presentation_Homo sapiens_hsa046121.29706667
23Pertussis_Homo sapiens_hsa051331.26066008
24Legionellosis_Homo sapiens_hsa051341.25630742
25Apoptosis_Homo sapiens_hsa042101.25619288
26Non-small cell lung cancer_Homo sapiens_hsa052231.25436823
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.25375920
28Tuberculosis_Homo sapiens_hsa051521.24531592
29NF-kappa B signaling pathway_Homo sapiens_hsa040641.21321622
30Neurotrophin signaling pathway_Homo sapiens_hsa047221.20963360
31TNF signaling pathway_Homo sapiens_hsa046681.20164077
32MicroRNAs in cancer_Homo sapiens_hsa052061.19244070
33Endometrial cancer_Homo sapiens_hsa052131.18632617
34Hepatitis B_Homo sapiens_hsa051611.18260403
35Amoebiasis_Homo sapiens_hsa051461.18145039
36Shigellosis_Homo sapiens_hsa051311.17751663
37Pentose phosphate pathway_Homo sapiens_hsa000301.15136745
38Measles_Homo sapiens_hsa051621.15045268
39Colorectal cancer_Homo sapiens_hsa052101.15008521
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.14864987
41ECM-receptor interaction_Homo sapiens_hsa045121.14692924
42Malaria_Homo sapiens_hsa051441.12015622
43Hematopoietic cell lineage_Homo sapiens_hsa046401.11143751
44HTLV-I infection_Homo sapiens_hsa051661.09151228
45Prolactin signaling pathway_Homo sapiens_hsa049171.06931800
46Notch signaling pathway_Homo sapiens_hsa043301.06637495
47Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.06280220
48VEGF signaling pathway_Homo sapiens_hsa043701.06107690
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.06034574
50Influenza A_Homo sapiens_hsa051641.05876901
51mTOR signaling pathway_Homo sapiens_hsa041501.05212206
52Viral carcinogenesis_Homo sapiens_hsa052031.03992745
53Central carbon metabolism in cancer_Homo sapiens_hsa052301.03923073
54Insulin resistance_Homo sapiens_hsa049311.03663950
55Transcriptional misregulation in cancer_Homo sapiens_hsa052021.03151902
56Salmonella infection_Homo sapiens_hsa051321.01303510
57Thyroid cancer_Homo sapiens_hsa052160.99614509
58Other glycan degradation_Homo sapiens_hsa005110.99463989
59NOD-like receptor signaling pathway_Homo sapiens_hsa046210.98732177
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.98678879
61Choline metabolism in cancer_Homo sapiens_hsa052310.98659595
62Herpes simplex infection_Homo sapiens_hsa051680.98406253
63ErbB signaling pathway_Homo sapiens_hsa040120.97812988
64Inositol phosphate metabolism_Homo sapiens_hsa005620.97792050
65Bladder cancer_Homo sapiens_hsa052190.97110639
66Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.96740992
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.93929024
68GnRH signaling pathway_Homo sapiens_hsa049120.92173495
69Chemokine signaling pathway_Homo sapiens_hsa040620.90665463
70Glioma_Homo sapiens_hsa052140.88253497
71T cell receptor signaling pathway_Homo sapiens_hsa046600.87556939
72Galactose metabolism_Homo sapiens_hsa000520.86885969
73Regulation of actin cytoskeleton_Homo sapiens_hsa048100.86597731
74HIF-1 signaling pathway_Homo sapiens_hsa040660.84960264
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.84867142
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.83002077
77Cell cycle_Homo sapiens_hsa041100.82013614
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81342558
79Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.80903272
80N-Glycan biosynthesis_Homo sapiens_hsa005100.80506419
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.80231234
82Carbohydrate digestion and absorption_Homo sapiens_hsa049730.80069012
83Pathways in cancer_Homo sapiens_hsa052000.78582043
84Longevity regulating pathway - mammal_Homo sapiens_hsa042110.77968487
85Fructose and mannose metabolism_Homo sapiens_hsa000510.77748411
86Renin-angiotensin system_Homo sapiens_hsa046140.76933846
87Hepatitis C_Homo sapiens_hsa051600.76875981
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76745119
89Prostate cancer_Homo sapiens_hsa052150.76431124
90Primary immunodeficiency_Homo sapiens_hsa053400.76388248
91Phagosome_Homo sapiens_hsa041450.76013203
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75408652
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.73867787
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.72546110
95Dilated cardiomyopathy_Homo sapiens_hsa054140.71560213
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.71503973
97TGF-beta signaling pathway_Homo sapiens_hsa043500.70317624
98AMPK signaling pathway_Homo sapiens_hsa041520.68324194
99FoxO signaling pathway_Homo sapiens_hsa040680.68122512
100p53 signaling pathway_Homo sapiens_hsa041150.65685598
101Staphylococcus aureus infection_Homo sapiens_hsa051500.65140387
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65120624
103Renal cell carcinoma_Homo sapiens_hsa052110.64903937
104Rap1 signaling pathway_Homo sapiens_hsa040150.64459327
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64032821
106Hippo signaling pathway_Homo sapiens_hsa043900.61159510
107Endocytosis_Homo sapiens_hsa041440.60857322
108Graft-versus-host disease_Homo sapiens_hsa053320.60389200
109Intestinal immune network for IgA production_Homo sapiens_hsa046720.60304744
110Estrogen signaling pathway_Homo sapiens_hsa049150.59733702
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59712141
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.58804972
113Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.57602085
114Insulin signaling pathway_Homo sapiens_hsa049100.57518324
115Allograft rejection_Homo sapiens_hsa053300.56759729
116Glycerophospholipid metabolism_Homo sapiens_hsa005640.56174517
117Type II diabetes mellitus_Homo sapiens_hsa049300.56001869
118African trypanosomiasis_Homo sapiens_hsa051430.55520265
119Dorso-ventral axis formation_Homo sapiens_hsa043200.52704872
120Autoimmune thyroid disease_Homo sapiens_hsa053200.50764323

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