

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of integrated proviral latency (GO:0075713) | 4.96020159 |
| 2 | ribosome assembly (GO:0042255) | 4.49421265 |
| 3 | chromatin remodeling at centromere (GO:0031055) | 4.38413830 |
| 4 | CENP-A containing nucleosome assembly (GO:0034080) | 4.37582484 |
| 5 | DNA double-strand break processing (GO:0000729) | 4.23956906 |
| 6 | nuclear pore organization (GO:0006999) | 4.03972778 |
| 7 | nuclear pore complex assembly (GO:0051292) | 4.03121458 |
| 8 | mitotic metaphase plate congression (GO:0007080) | 3.90716398 |
| 9 | histone exchange (GO:0043486) | 3.86700623 |
| 10 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.79270845 |
| 11 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.79270845 |
| 12 | DNA damage response, detection of DNA damage (GO:0042769) | 3.79116052 |
| 13 | proteasome assembly (GO:0043248) | 3.77117780 |
| 14 | protein neddylation (GO:0045116) | 3.71445855 |
| 15 | regulation of helicase activity (GO:0051095) | 3.65917696 |
| 16 | DNA replication checkpoint (GO:0000076) | 3.64290926 |
| 17 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.63419941 |
| 18 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.62434534 |
| 19 | establishment of viral latency (GO:0019043) | 3.61054592 |
| 20 | DNA replication-independent nucleosome organization (GO:0034724) | 3.59858502 |
| 21 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.59858502 |
| 22 | spindle checkpoint (GO:0031577) | 3.53708614 |
| 23 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.53383856 |
| 24 | negative regulation of sister chromatid segregation (GO:0033046) | 3.53383856 |
| 25 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.53383856 |
| 26 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.53383856 |
| 27 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.53383856 |
| 28 | cullin deneddylation (GO:0010388) | 3.52997239 |
| 29 | mitotic spindle checkpoint (GO:0071174) | 3.52576730 |
| 30 | metaphase plate congression (GO:0051310) | 3.51352492 |
| 31 | IMP biosynthetic process (GO:0006188) | 3.50591841 |
| 32 | regulation of centriole replication (GO:0046599) | 3.49831955 |
| 33 | protein localization to kinetochore (GO:0034501) | 3.48091475 |
| 34 | negative regulation of chromosome segregation (GO:0051985) | 3.44869978 |
| 35 | non-recombinational repair (GO:0000726) | 3.41970980 |
| 36 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.41970980 |
| 37 | negative regulation of DNA recombination (GO:0045910) | 3.37587113 |
| 38 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.30915207 |
| 39 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.28881901 |
| 40 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.28881901 |
| 41 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.28863922 |
| 42 | histone mRNA metabolic process (GO:0008334) | 3.24600040 |
| 43 | pre-miRNA processing (GO:0031054) | 3.24147603 |
| 44 | IMP metabolic process (GO:0046040) | 3.22896045 |
| 45 | protein deneddylation (GO:0000338) | 3.20531545 |
| 46 | mitotic spindle assembly checkpoint (GO:0007094) | 3.20378591 |
| 47 | purine nucleobase biosynthetic process (GO:0009113) | 3.19522476 |
| 48 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.18838544 |
| 49 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.18838544 |
| 50 | regulation of sister chromatid segregation (GO:0033045) | 3.18838544 |
| 51 | spindle assembly checkpoint (GO:0071173) | 3.15513968 |
| 52 | DNA ligation (GO:0006266) | 3.12630030 |
| 53 | regulation of chromosome segregation (GO:0051983) | 3.10033861 |
| 54 | paraxial mesoderm development (GO:0048339) | 3.07005506 |
| 55 | chaperone-mediated protein transport (GO:0072321) | 3.05403004 |
| 56 | telomere maintenance via telomerase (GO:0007004) | 3.03367058 |
| 57 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.01278001 |
| 58 | negative regulation of ligase activity (GO:0051352) | 3.01278001 |
| 59 | RNA-dependent DNA replication (GO:0006278) | 3.00590351 |
| 60 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.99857947 |
| 61 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.99389322 |
| 62 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.99389322 |
| 63 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.97429893 |
| 64 | mitotic G2/M transition checkpoint (GO:0044818) | 2.96131388 |
| 65 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.94575616 |
| 66 | establishment of chromosome localization (GO:0051303) | 2.91952106 |
| 67 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.91324880 |
| 68 | nucleobase biosynthetic process (GO:0046112) | 2.90708726 |
| 69 | presynaptic membrane assembly (GO:0097105) | 2.90102852 |
| 70 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.85912778 |
| 71 | protein complex localization (GO:0031503) | 2.85480665 |
| 72 | pore complex assembly (GO:0046931) | 2.85129710 |
| 73 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.84576763 |
| 74 | response to X-ray (GO:0010165) | 2.82217465 |
| 75 | anterior/posterior axis specification, embryo (GO:0008595) | 2.82068763 |
| 76 | maturation of 5.8S rRNA (GO:0000460) | 2.80522161 |
| 77 | negative regulation of mitosis (GO:0045839) | 2.78762453 |
| 78 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.76318216 |
| 79 | mitotic nuclear envelope disassembly (GO:0007077) | 2.74845169 |
| 80 | L-serine metabolic process (GO:0006563) | 2.70779618 |
| 81 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.66840067 |
| 82 | respiratory chain complex IV assembly (GO:0008535) | 2.65912451 |
| 83 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.64316641 |
| 84 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.64316641 |
| 85 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.63411705 |
| 86 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.62756053 |
| 87 | regulation of coenzyme metabolic process (GO:0051196) | 2.62692511 |
| 88 | regulation of cofactor metabolic process (GO:0051193) | 2.62692511 |
| 89 | female gonad development (GO:0008585) | 2.62495620 |
| 90 | protein localization to chromosome, centromeric region (GO:0071459) | 2.62348756 |
| 91 | lactate metabolic process (GO:0006089) | 2.61884397 |
| 92 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.61404115 |
| 93 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) | 2.61347517 |
| 94 | cellular protein complex localization (GO:0034629) | 2.61218676 |
| 95 | nuclear envelope disassembly (GO:0051081) | 2.60525104 |
| 96 | membrane disassembly (GO:0030397) | 2.60525104 |
| 97 | ATP-dependent chromatin remodeling (GO:0043044) | 2.60076792 |
| 98 | tRNA aminoacylation for protein translation (GO:0006418) | 2.60023308 |
| 99 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.59960192 |
| 100 | ventricular cardiac muscle cell development (GO:0055015) | 2.59458526 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.28457815 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.79432142 |
| 3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.20191161 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.09592634 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.85231990 |
| 6 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.63203687 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.61049915 |
| 8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.47979955 |
| 9 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.44303118 |
| 10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.29835728 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.28841338 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.21051254 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.20270574 |
| 14 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.19913490 |
| 15 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.19045609 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.16410025 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.15088478 |
| 18 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.01672099 |
| 19 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.99081931 |
| 20 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.90179202 |
| 21 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.85717688 |
| 22 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.85572780 |
| 23 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.85039388 |
| 24 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.83905018 |
| 25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.82727937 |
| 26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.76477852 |
| 27 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.75379220 |
| 28 | P300_19829295_ChIP-Seq_ESCs_Human | 1.73428968 |
| 29 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.67832248 |
| 30 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.67791141 |
| 31 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.66683230 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.64027894 |
| 33 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.60392190 |
| 34 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.58723784 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.58581633 |
| 36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.57264842 |
| 37 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.55739572 |
| 38 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.55111152 |
| 39 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.52753388 |
| 40 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.52494334 |
| 41 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.47793877 |
| 42 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.45838063 |
| 43 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.44780935 |
| 44 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.42504293 |
| 45 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.42112325 |
| 46 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.40607133 |
| 47 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.38506659 |
| 48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.38289856 |
| 49 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.38179409 |
| 50 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.36193164 |
| 51 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.35638942 |
| 52 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.34954857 |
| 53 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.34676662 |
| 54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34430672 |
| 55 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.33488587 |
| 56 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.32263491 |
| 57 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.29865166 |
| 58 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29686586 |
| 59 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.29110073 |
| 60 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.25133705 |
| 61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.23272005 |
| 62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.20009489 |
| 63 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.18592624 |
| 64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.18478831 |
| 65 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17973840 |
| 66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.16218509 |
| 67 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.14286007 |
| 68 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.13361122 |
| 69 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.12656386 |
| 70 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.11914885 |
| 71 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.10830652 |
| 72 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.10558468 |
| 73 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.08404365 |
| 74 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.08404365 |
| 75 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.08404365 |
| 76 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.08175173 |
| 77 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.07944092 |
| 78 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.07540887 |
| 79 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.06379348 |
| 80 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.06301546 |
| 81 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.05774347 |
| 82 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.05438971 |
| 83 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.04736925 |
| 84 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.04474469 |
| 85 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03344912 |
| 86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.02270652 |
| 87 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.02153013 |
| 88 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01630984 |
| 89 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.99296890 |
| 90 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.98896845 |
| 91 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.98733209 |
| 92 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.98361520 |
| 93 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.98274167 |
| 94 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.98009479 |
| 95 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.97601314 |
| 96 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95251800 |
| 97 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95130366 |
| 98 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.94512549 |
| 99 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92337944 |
| 100 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.92198571 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003941_abnormal_skin_development | 4.27533061 |
| 2 | MP0004957_abnormal_blastocyst_morpholog | 3.29322296 |
| 3 | MP0003890_abnormal_embryonic-extraembry | 2.90998800 |
| 4 | MP0010094_abnormal_chromosome_stability | 2.90202445 |
| 5 | MP0008057_abnormal_DNA_replication | 2.87905154 |
| 6 | MP0008058_abnormal_DNA_repair | 2.84350898 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.56189874 |
| 8 | MP0008932_abnormal_embryonic_tissue | 2.46561034 |
| 9 | MP0002102_abnormal_ear_morphology | 2.44531592 |
| 10 | MP0003111_abnormal_nucleus_morphology | 2.42521154 |
| 11 | MP0002254_reproductive_system_inflammat | 2.39297364 |
| 12 | MP0003077_abnormal_cell_cycle | 2.17679627 |
| 13 | MP0003718_maternal_effect | 2.16151318 |
| 14 | MP0009697_abnormal_copulation | 2.12962644 |
| 15 | MP0001188_hyperpigmentation | 2.10672330 |
| 16 | MP0008007_abnormal_cellular_replicative | 2.04851592 |
| 17 | MP0001529_abnormal_vocalization | 1.98049460 |
| 18 | MP0010352_gastrointestinal_tract_polyps | 1.94525390 |
| 19 | MP0001293_anophthalmia | 1.93719016 |
| 20 | MP0008877_abnormal_DNA_methylation | 1.90791301 |
| 21 | MP0003567_abnormal_fetal_cardiomyocyte | 1.84661352 |
| 22 | MP0009672_abnormal_birth_weight | 1.82913652 |
| 23 | MP0003119_abnormal_digestive_system | 1.76546149 |
| 24 | MP0003937_abnormal_limbs/digits/tail_de | 1.76134851 |
| 25 | MP0001177_atelectasis | 1.75374832 |
| 26 | MP0001730_embryonic_growth_arrest | 1.71597365 |
| 27 | MP0006054_spinal_hemorrhage | 1.67613019 |
| 28 | MP0006072_abnormal_retinal_apoptosis | 1.50849078 |
| 29 | MP0003121_genomic_imprinting | 1.50801025 |
| 30 | MP0003123_paternal_imprinting | 1.48019226 |
| 31 | MP0002084_abnormal_developmental_patter | 1.46329731 |
| 32 | MP0001672_abnormal_embryogenesis/_devel | 1.41701704 |
| 33 | MP0005380_embryogenesis_phenotype | 1.41701704 |
| 34 | MP0001984_abnormal_olfaction | 1.41435094 |
| 35 | MP0002233_abnormal_nose_morphology | 1.40266003 |
| 36 | MP0009703_decreased_birth_body | 1.39921042 |
| 37 | MP0001697_abnormal_embryo_size | 1.38681213 |
| 38 | MP0002085_abnormal_embryonic_tissue | 1.38461443 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.37591488 |
| 40 | MP0002697_abnormal_eye_size | 1.35333774 |
| 41 | MP0003122_maternal_imprinting | 1.34906728 |
| 42 | MP0002938_white_spotting | 1.34287107 |
| 43 | MP0002751_abnormal_autonomic_nervous | 1.33646191 |
| 44 | MP0001286_abnormal_eye_development | 1.33427859 |
| 45 | MP0005248_abnormal_Harderian_gland | 1.28259500 |
| 46 | MP0005367_renal/urinary_system_phenotyp | 1.27968883 |
| 47 | MP0000516_abnormal_urinary_system | 1.27968883 |
| 48 | MP0002090_abnormal_vision | 1.27064975 |
| 49 | MP0010386_abnormal_urinary_bladder | 1.24317761 |
| 50 | MP0000350_abnormal_cell_proliferation | 1.22953482 |
| 51 | MP0001299_abnormal_eye_distance/ | 1.21056964 |
| 52 | MP0003984_embryonic_growth_retardation | 1.19009002 |
| 53 | MP0003195_calcinosis | 1.18881377 |
| 54 | MP0004270_analgesia | 1.18408565 |
| 55 | MP0002088_abnormal_embryonic_growth/wei | 1.18248121 |
| 56 | MP0004197_abnormal_fetal_growth/weight/ | 1.14864831 |
| 57 | MP0000647_abnormal_sebaceous_gland | 1.12647458 |
| 58 | MP0003221_abnormal_cardiomyocyte_apopto | 1.11263710 |
| 59 | MP0002736_abnormal_nociception_after | 1.09107017 |
| 60 | MP0004133_heterotaxia | 1.08616795 |
| 61 | MP0002111_abnormal_tail_morphology | 1.04957216 |
| 62 | MP0010234_abnormal_vibrissa_follicle | 1.02423109 |
| 63 | MP0002080_prenatal_lethality | 1.01609025 |
| 64 | MP0004215_abnormal_myocardial_fiber | 0.99338349 |
| 65 | MP0010307_abnormal_tumor_latency | 0.99335564 |
| 66 | MP0000537_abnormal_urethra_morphology | 0.98356925 |
| 67 | MP0003880_abnormal_central_pattern | 0.97645961 |
| 68 | MP0005253_abnormal_eye_physiology | 0.94383987 |
| 69 | MP0004272_abnormal_basement_membrane | 0.92595608 |
| 70 | MP0002086_abnormal_extraembryonic_tissu | 0.90805571 |
| 71 | MP0000358_abnormal_cell_content/ | 0.90791006 |
| 72 | MP0003787_abnormal_imprinting | 0.89613686 |
| 73 | MP0003861_abnormal_nervous_system | 0.88114731 |
| 74 | MP0000428_abnormal_craniofacial_morphol | 0.86271471 |
| 75 | MP0003755_abnormal_palate_morphology | 0.85840222 |
| 76 | MP0008789_abnormal_olfactory_epithelium | 0.84490544 |
| 77 | MP0003786_premature_aging | 0.81912472 |
| 78 | MP0003186_abnormal_redox_activity | 0.81478313 |
| 79 | MP0006292_abnormal_olfactory_placode | 0.81456948 |
| 80 | MP0003136_yellow_coat_color | 0.81269230 |
| 81 | MP0005187_abnormal_penis_morphology | 0.80652719 |
| 82 | MP0003385_abnormal_body_wall | 0.79087490 |
| 83 | MP0005391_vision/eye_phenotype | 0.78421132 |
| 84 | MP0000372_irregular_coat_pigmentation | 0.78300215 |
| 85 | MP0001486_abnormal_startle_reflex | 0.77501429 |
| 86 | MP0003935_abnormal_craniofacial_develop | 0.75088830 |
| 87 | MP0001915_intracranial_hemorrhage | 0.74350881 |
| 88 | MP0005395_other_phenotype | 0.73953581 |
| 89 | MP0005408_hypopigmentation | 0.73888509 |
| 90 | MP0003806_abnormal_nucleotide_metabolis | 0.73584023 |
| 91 | MP0000432_abnormal_head_morphology | 0.73057816 |
| 92 | MP0000579_abnormal_nail_morphology | 0.72029484 |
| 93 | MP0001324_abnormal_eye_pigmentation | 0.71936056 |
| 94 | MP0002184_abnormal_innervation | 0.69858201 |
| 95 | MP0002092_abnormal_eye_morphology | 0.69501080 |
| 96 | MP0002081_perinatal_lethality | 0.67024740 |
| 97 | MP0009046_muscle_twitch | 0.66821400 |
| 98 | MP0000631_abnormal_neuroendocrine_gland | 0.66632855 |
| 99 | MP0002734_abnormal_mechanical_nocicepti | 0.66457128 |
| 100 | MP0001485_abnormal_pinna_reflex | 0.65655156 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 3.89826462 |
| 2 | Colon cancer (HP:0003003) | 3.66254003 |
| 3 | Cortical dysplasia (HP:0002539) | 3.40441756 |
| 4 | Papillary thyroid carcinoma (HP:0002895) | 3.05854452 |
| 5 | Ependymoma (HP:0002888) | 3.04191956 |
| 6 | Rhabdomyosarcoma (HP:0002859) | 3.00860966 |
| 7 | Abnormal lung lobation (HP:0002101) | 3.00363995 |
| 8 | Abnormality of methionine metabolism (HP:0010901) | 2.94073596 |
| 9 | Medulloblastoma (HP:0002885) | 2.86597724 |
| 10 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.78360967 |
| 11 | Biliary tract neoplasm (HP:0100574) | 2.72744452 |
| 12 | Embryonal renal neoplasm (HP:0011794) | 2.72728060 |
| 13 | Absent eyebrow (HP:0002223) | 2.67947232 |
| 14 | Agnosia (HP:0010524) | 2.67789217 |
| 15 | Thyroid carcinoma (HP:0002890) | 2.65120737 |
| 16 | Methylmalonic acidemia (HP:0002912) | 2.60119828 |
| 17 | Glioma (HP:0009733) | 2.59027505 |
| 18 | Hypoglycemic seizures (HP:0002173) | 2.55207047 |
| 19 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.54708106 |
| 20 | Acute necrotizing encephalopathy (HP:0006965) | 2.49780593 |
| 21 | Increased hepatocellular lipid droplets (HP:0006565) | 2.49656904 |
| 22 | Abnormality of chromosome stability (HP:0003220) | 2.48721330 |
| 23 | Abnormality of the astrocytes (HP:0100707) | 2.42953512 |
| 24 | Astrocytoma (HP:0009592) | 2.42953512 |
| 25 | Increased serum pyruvate (HP:0003542) | 2.39801982 |
| 26 | Neoplasm of the small intestine (HP:0100833) | 2.39395057 |
| 27 | Acute encephalopathy (HP:0006846) | 2.36378464 |
| 28 | Neoplasm of the adrenal gland (HP:0100631) | 2.35140390 |
| 29 | Neoplasm of the colon (HP:0100273) | 2.34839551 |
| 30 | Progressive macrocephaly (HP:0004481) | 2.34296363 |
| 31 | Abnormality of serum amino acid levels (HP:0003112) | 2.33771574 |
| 32 | Postnatal microcephaly (HP:0005484) | 2.32258481 |
| 33 | Intestinal atresia (HP:0011100) | 2.32160961 |
| 34 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.31815580 |
| 35 | Spastic diplegia (HP:0001264) | 2.27866388 |
| 36 | Meckel diverticulum (HP:0002245) | 2.25724317 |
| 37 | Stenosis of the external auditory canal (HP:0000402) | 2.25067242 |
| 38 | Septo-optic dysplasia (HP:0100842) | 2.24873998 |
| 39 | Hepatoblastoma (HP:0002884) | 2.23327215 |
| 40 | Hypoglycemic coma (HP:0001325) | 2.20322023 |
| 41 | Degeneration of anterior horn cells (HP:0002398) | 2.18160638 |
| 42 | Abnormality of the anterior horn cell (HP:0006802) | 2.18160638 |
| 43 | Bifid tongue (HP:0010297) | 2.16205943 |
| 44 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.14583616 |
| 45 | Ovarian neoplasm (HP:0100615) | 2.14107877 |
| 46 | Abnormality of glycolysis (HP:0004366) | 2.13693334 |
| 47 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.13600595 |
| 48 | Megaloblastic anemia (HP:0001889) | 2.13100754 |
| 49 | Abnormality of the ileum (HP:0001549) | 2.13072714 |
| 50 | Abnormal hair whorl (HP:0010721) | 2.12522755 |
| 51 | Birth length less than 3rd percentile (HP:0003561) | 2.11423666 |
| 52 | Lipid accumulation in hepatocytes (HP:0006561) | 2.10839567 |
| 53 | Breast carcinoma (HP:0003002) | 2.10609976 |
| 54 | Uterine neoplasm (HP:0010784) | 2.09281046 |
| 55 | Hyperglycinemia (HP:0002154) | 2.02342194 |
| 56 | Myelomeningocele (HP:0002475) | 2.00944472 |
| 57 | Neoplasm of striated muscle (HP:0009728) | 1.95693090 |
| 58 | Chromsome breakage (HP:0040012) | 1.93774766 |
| 59 | Supernumerary spleens (HP:0009799) | 1.91191913 |
| 60 | Volvulus (HP:0002580) | 1.90651546 |
| 61 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.90217278 |
| 62 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.89549142 |
| 63 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.89407259 |
| 64 | Facial cleft (HP:0002006) | 1.88624709 |
| 65 | Neoplasm of the rectum (HP:0100743) | 1.87595958 |
| 66 | Shoulder girdle muscle weakness (HP:0003547) | 1.86853947 |
| 67 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.85810136 |
| 68 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.85810136 |
| 69 | Genital tract atresia (HP:0001827) | 1.84509760 |
| 70 | Increased CSF lactate (HP:0002490) | 1.83130154 |
| 71 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.83118209 |
| 72 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.83118209 |
| 73 | Leukodystrophy (HP:0002415) | 1.82789526 |
| 74 | Absent hair (HP:0002298) | 1.80881898 |
| 75 | Neuroendocrine neoplasm (HP:0100634) | 1.80605451 |
| 76 | Small intestinal stenosis (HP:0012848) | 1.80343181 |
| 77 | Duodenal stenosis (HP:0100867) | 1.80343181 |
| 78 | Gonadotropin excess (HP:0000837) | 1.80126971 |
| 79 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.80025871 |
| 80 | Gastrointestinal carcinoma (HP:0002672) | 1.80025871 |
| 81 | Cerebral edema (HP:0002181) | 1.79612771 |
| 82 | Neoplasm of the thyroid gland (HP:0100031) | 1.79286092 |
| 83 | Aqueductal stenosis (HP:0002410) | 1.79083717 |
| 84 | Abnormality of the duodenum (HP:0002246) | 1.78581011 |
| 85 | Methylmalonic aciduria (HP:0012120) | 1.78553537 |
| 86 | Vaginal atresia (HP:0000148) | 1.77197374 |
| 87 | Angiofibromas (HP:0010615) | 1.76725572 |
| 88 | Adenoma sebaceum (HP:0009720) | 1.76725572 |
| 89 | Neoplasm of the adrenal cortex (HP:0100641) | 1.76158385 |
| 90 | Multiple enchondromatosis (HP:0005701) | 1.75381722 |
| 91 | Progressive inability to walk (HP:0002505) | 1.75058704 |
| 92 | Homocystinuria (HP:0002156) | 1.72570779 |
| 93 | Abnormality of homocysteine metabolism (HP:0010919) | 1.72570779 |
| 94 | Gastrointestinal atresia (HP:0002589) | 1.71404460 |
| 95 | Symptomatic seizures (HP:0011145) | 1.71073528 |
| 96 | Renal Fanconi syndrome (HP:0001994) | 1.70006206 |
| 97 | Type I transferrin isoform profile (HP:0003642) | 1.69453933 |
| 98 | Mitochondrial inheritance (HP:0001427) | 1.68802824 |
| 99 | Scrotal hypoplasia (HP:0000046) | 1.68489850 |
| 100 | Abnormality of vitamin B metabolism (HP:0004340) | 1.68295165 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 3.43493791 |
| 2 | SRPK1 | 3.33406398 |
| 3 | MKNK2 | 3.13493866 |
| 4 | TRIM28 | 3.04519373 |
| 5 | MKNK1 | 2.76576098 |
| 6 | BUB1 | 2.76242588 |
| 7 | TTK | 2.72243040 |
| 8 | EIF2AK3 | 2.63334810 |
| 9 | MST4 | 2.60500220 |
| 10 | PLK3 | 2.51661828 |
| 11 | TNIK | 2.44579035 |
| 12 | CDC7 | 2.25218474 |
| 13 | BCR | 2.19448067 |
| 14 | WNK3 | 2.14536586 |
| 15 | EIF2AK1 | 2.13451542 |
| 16 | NEK1 | 2.12591656 |
| 17 | PBK | 1.98365757 |
| 18 | ZAK | 1.87454632 |
| 19 | MAP3K4 | 1.83656341 |
| 20 | STK38L | 1.81228863 |
| 21 | PLK4 | 1.79403171 |
| 22 | ERBB3 | 1.67902291 |
| 23 | BRSK2 | 1.66678532 |
| 24 | TAF1 | 1.52623713 |
| 25 | MAP3K12 | 1.51209185 |
| 26 | CASK | 1.46274764 |
| 27 | WEE1 | 1.39009420 |
| 28 | ACVR1B | 1.35507062 |
| 29 | BMPR1B | 1.28437381 |
| 30 | MAP2K7 | 1.27754013 |
| 31 | NUAK1 | 1.26872875 |
| 32 | STK16 | 1.25790197 |
| 33 | PLK2 | 1.25391507 |
| 34 | PLK1 | 1.25277541 |
| 35 | CSNK1G1 | 1.24485699 |
| 36 | MAP4K2 | 1.21007216 |
| 37 | STK3 | 1.20774559 |
| 38 | CSNK1G2 | 1.17242255 |
| 39 | LATS1 | 1.12579961 |
| 40 | DYRK3 | 1.06207052 |
| 41 | ALK | 1.03784135 |
| 42 | VRK2 | 1.02461362 |
| 43 | CSNK1G3 | 1.02434046 |
| 44 | VRK1 | 1.02258387 |
| 45 | FRK | 1.00001104 |
| 46 | DYRK2 | 0.96839673 |
| 47 | STK24 | 0.96612979 |
| 48 | FGFR2 | 0.94916070 |
| 49 | CSNK1A1L | 0.94434746 |
| 50 | NME1 | 0.94301729 |
| 51 | FGFR1 | 0.93239443 |
| 52 | ERBB4 | 0.92039789 |
| 53 | LATS2 | 0.91132968 |
| 54 | PNCK | 0.88111233 |
| 55 | RPS6KA4 | 0.86420162 |
| 56 | PASK | 0.82058377 |
| 57 | PAK4 | 0.79090224 |
| 58 | YES1 | 0.77772595 |
| 59 | EIF2AK2 | 0.76695039 |
| 60 | OXSR1 | 0.75807456 |
| 61 | BRD4 | 0.68930178 |
| 62 | GRK1 | 0.68531747 |
| 63 | MINK1 | 0.68039139 |
| 64 | ATM | 0.66162667 |
| 65 | SIK3 | 0.65953219 |
| 66 | PDK2 | 0.65290282 |
| 67 | BRSK1 | 0.62338589 |
| 68 | NLK | 0.61239053 |
| 69 | ATR | 0.60930119 |
| 70 | PRKCE | 0.56970003 |
| 71 | FLT3 | 0.55202474 |
| 72 | CHEK2 | 0.54997809 |
| 73 | CDK6 | 0.54783678 |
| 74 | CSNK1E | 0.53623663 |
| 75 | PRKCG | 0.50092482 |
| 76 | AURKB | 0.47544547 |
| 77 | CDK3 | 0.47087168 |
| 78 | CDK19 | 0.46701030 |
| 79 | TGFBR1 | 0.45194076 |
| 80 | FER | 0.41530546 |
| 81 | NEK2 | 0.40589319 |
| 82 | PAK3 | 0.40462932 |
| 83 | CHEK1 | 0.38533022 |
| 84 | EPHA4 | 0.38405517 |
| 85 | STK4 | 0.36784894 |
| 86 | CSNK2A1 | 0.36693050 |
| 87 | CLK1 | 0.35040009 |
| 88 | DAPK1 | 0.34375358 |
| 89 | STK39 | 0.34125030 |
| 90 | CSNK2A2 | 0.33958977 |
| 91 | CDK1 | 0.33797145 |
| 92 | KSR1 | 0.32984230 |
| 93 | PRKDC | 0.32210582 |
| 94 | MAP3K5 | 0.31811592 |
| 95 | CDK18 | 0.31634412 |
| 96 | MAP2K4 | 0.29141658 |
| 97 | CDK14 | 0.28300559 |
| 98 | EGFR | 0.28299234 |
| 99 | TIE1 | 0.28187585 |
| 100 | MARK1 | 0.27847099 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protein export_Homo sapiens_hsa03060 | 3.77293553 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.77261816 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.22861965 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.02077972 |
| 5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.83638895 |
| 6 | RNA transport_Homo sapiens_hsa03013 | 2.40675569 |
| 7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.36826757 |
| 8 | Basal transcription factors_Homo sapiens_hsa03022 | 2.29304185 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.25684735 |
| 10 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.06691125 |
| 11 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.03394303 |
| 12 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.02336508 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.00901725 |
| 14 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.95064596 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.94381696 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.92308436 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.90842887 |
| 18 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.89281937 |
| 19 | Cell cycle_Homo sapiens_hsa04110 | 1.86465315 |
| 20 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.83742830 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.78459396 |
| 22 | Parkinsons disease_Homo sapiens_hsa05012 | 1.68128049 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.65785358 |
| 24 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.65744168 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.57377869 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.55817588 |
| 27 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.53656949 |
| 28 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.52920040 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.46383823 |
| 30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.44737879 |
| 31 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.28376395 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.27016794 |
| 33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.26768341 |
| 34 | Base excision repair_Homo sapiens_hsa03410 | 1.22130556 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.20485623 |
| 36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.20249974 |
| 37 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.15846167 |
| 38 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.11002087 |
| 39 | Alzheimers disease_Homo sapiens_hsa05010 | 1.01702062 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.00149811 |
| 41 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.99979995 |
| 42 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.97729833 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.95069686 |
| 44 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.92108711 |
| 45 | Nicotine addiction_Homo sapiens_hsa05033 | 0.91065908 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.88871224 |
| 47 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.85759114 |
| 48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.85327150 |
| 49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.81367827 |
| 50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.81346388 |
| 51 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.80670220 |
| 52 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.79903964 |
| 53 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.74239380 |
| 54 | Adherens junction_Homo sapiens_hsa04520 | 0.74207726 |
| 55 | Carbon metabolism_Homo sapiens_hsa01200 | 0.73546244 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.73268128 |
| 57 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.72441262 |
| 58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.70341742 |
| 59 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.70286441 |
| 60 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68732432 |
| 61 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.67057806 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66867058 |
| 63 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.65621653 |
| 64 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.64517214 |
| 65 | Tight junction_Homo sapiens_hsa04530 | 0.59855325 |
| 66 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.58487712 |
| 67 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.57972399 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57279395 |
| 69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.55875318 |
| 70 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.52174297 |
| 71 | Thyroid cancer_Homo sapiens_hsa05216 | 0.51241279 |
| 72 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.50724664 |
| 73 | GABAergic synapse_Homo sapiens_hsa04727 | 0.49861141 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47936968 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.47068386 |
| 76 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.44715793 |
| 77 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.42045912 |
| 78 | Taste transduction_Homo sapiens_hsa04742 | 0.41106541 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38862026 |
| 80 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.38012017 |
| 81 | Ribosome_Homo sapiens_hsa03010 | 0.37602622 |
| 82 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.36474136 |
| 83 | Peroxisome_Homo sapiens_hsa04146 | 0.34330744 |
| 84 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32763938 |
| 85 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.32142114 |
| 86 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.32112462 |
| 87 | Colorectal cancer_Homo sapiens_hsa05210 | 0.31255330 |
| 88 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.31212750 |
| 89 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.31000442 |
| 90 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.30681304 |
| 91 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.29714430 |
| 92 | Long-term depression_Homo sapiens_hsa04730 | 0.26890530 |
| 93 | Circadian rhythm_Homo sapiens_hsa04710 | 0.26561152 |
| 94 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.23011802 |
| 95 | Gap junction_Homo sapiens_hsa04540 | 0.22384040 |
| 96 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.20764067 |
| 97 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.18093251 |
| 98 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.17972884 |
| 99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.16805960 |
| 100 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.14383074 |

