TMEM17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.14017570
2chaperone-mediated protein transport (GO:0072321)5.09815411
3ATP synthesis coupled proton transport (GO:0015986)4.91023581
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.91023581
5neuron cell-cell adhesion (GO:0007158)4.72435271
6mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.64077959
7establishment of protein localization to mitochondrial membrane (GO:0090151)4.62413988
8protein neddylation (GO:0045116)4.40335301
9cullin deneddylation (GO:0010388)4.30903921
10behavioral response to nicotine (GO:0035095)4.23813638
11mitochondrial respiratory chain complex I assembly (GO:0032981)4.15441171
12NADH dehydrogenase complex assembly (GO:0010257)4.15441171
13mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.15441171
14proteasome assembly (GO:0043248)4.15363453
15epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.12976724
16epithelial cilium movement (GO:0003351)4.12067615
17protein complex biogenesis (GO:0070271)4.06925680
18protein deneddylation (GO:0000338)4.00639295
19platelet dense granule organization (GO:0060155)3.97710799
20mitochondrial respiratory chain complex assembly (GO:0033108)3.86635662
21respiratory electron transport chain (GO:0022904)3.72016963
22electron transport chain (GO:0022900)3.64517114
23cilium movement (GO:0003341)3.55517147
24respiratory chain complex IV assembly (GO:0008535)3.53426834
25water-soluble vitamin biosynthetic process (GO:0042364)3.47377646
26negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.46527339
27cellular ketone body metabolic process (GO:0046950)3.41471731
28piRNA metabolic process (GO:0034587)3.41240704
29cilium morphogenesis (GO:0060271)3.39779304
30response to histamine (GO:0034776)3.39431596
31transcription elongation from RNA polymerase III promoter (GO:0006385)3.37678979
32termination of RNA polymerase III transcription (GO:0006386)3.37678979
33L-fucose catabolic process (GO:0042355)3.36920121
34fucose catabolic process (GO:0019317)3.36920121
35L-fucose metabolic process (GO:0042354)3.36920121
36indolalkylamine metabolic process (GO:0006586)3.33639169
37regulation of glucokinase activity (GO:0033131)3.33062971
38regulation of hexokinase activity (GO:1903299)3.33062971
39presynaptic membrane assembly (GO:0097105)3.32128571
40sensory perception of smell (GO:0007608)3.30059531
41nonmotile primary cilium assembly (GO:0035058)3.29799605
427-methylguanosine mRNA capping (GO:0006370)3.26540333
43pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.24951759
447-methylguanosine RNA capping (GO:0009452)3.24874475
45RNA capping (GO:0036260)3.24874475
46negative regulation of microtubule polymerization (GO:0031115)3.21277147
47inner mitochondrial membrane organization (GO:0007007)3.19983967
48regulation of cellular amino acid metabolic process (GO:0006521)3.19715732
49cytochrome complex assembly (GO:0017004)3.19217091
50dopamine transport (GO:0015872)3.18664537
51protein polyglutamylation (GO:0018095)3.16144839
52glycerophospholipid catabolic process (GO:0046475)3.15533149
53ketone body metabolic process (GO:1902224)3.14427834
54negative regulation of ligase activity (GO:0051352)3.14247996
55negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.14247996
56positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.13091211
57neurotransmitter uptake (GO:0001504)3.12709713
58protein targeting to mitochondrion (GO:0006626)3.12346580
59establishment of protein localization to mitochondrion (GO:0072655)3.08999467
60negative regulation of telomere maintenance (GO:0032205)3.01836989
61* cilium organization (GO:0044782)3.00863251
62GTP biosynthetic process (GO:0006183)3.00158384
63regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.98457850
64DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.96580880
65tryptophan catabolic process (GO:0006569)2.96572160
66indole-containing compound catabolic process (GO:0042436)2.96572160
67indolalkylamine catabolic process (GO:0046218)2.96572160
68* cilium assembly (GO:0042384)2.95802678
69protein localization to cilium (GO:0061512)2.95111723
70de novo posttranslational protein folding (GO:0051084)2.91430740
71protein localization to mitochondrion (GO:0070585)2.89821868
72axoneme assembly (GO:0035082)2.89203893
73intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.88374193
74signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.88374193
75de novo protein folding (GO:0006458)2.87927159
76regulation of catecholamine metabolic process (GO:0042069)2.87793258
77regulation of dopamine metabolic process (GO:0042053)2.87793258
78signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.85719571
79signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.85719571
80signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.85719571
81response to pheromone (GO:0019236)2.85353920
82preassembly of GPI anchor in ER membrane (GO:0016254)2.85183249
83postsynaptic membrane organization (GO:0001941)2.84902826
84kynurenine metabolic process (GO:0070189)2.84858568
85anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.83553630
86signal transduction involved in cell cycle checkpoint (GO:0072395)2.80711738
87deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.80585279
88inositol phosphate catabolic process (GO:0071545)2.79818530
89regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.79722605
90regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.79722605
91serotonin receptor signaling pathway (GO:0007210)2.78037844
92detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.77409876
93synaptic vesicle exocytosis (GO:0016079)2.76353907
94negative regulation of cytosolic calcium ion concentration (GO:0051481)2.74394518
95signal transduction involved in DNA damage checkpoint (GO:0072422)2.74336744
96signal transduction involved in DNA integrity checkpoint (GO:0072401)2.74336744
97presynaptic membrane organization (GO:0097090)2.74093490
98pyrimidine nucleobase catabolic process (GO:0006208)2.73692594
99regulation of cellular amine metabolic process (GO:0033238)2.73584539
100nucleobase catabolic process (GO:0046113)2.73411274
101axonemal dynein complex assembly (GO:0070286)2.73320476
102intraciliary transport (GO:0042073)2.72590482
103regulation of protein kinase A signaling (GO:0010738)2.70902489
104female mating behavior (GO:0060180)2.70591800
105inositol phosphate dephosphorylation (GO:0046855)2.69848625
106phosphorylated carbohydrate dephosphorylation (GO:0046838)2.69848625
107UTP biosynthetic process (GO:0006228)2.69239976
108detection of light stimulus involved in visual perception (GO:0050908)2.68475403
109detection of light stimulus involved in sensory perception (GO:0050962)2.68475403
110vocalization behavior (GO:0071625)2.68471018
111regulation of neurotransmitter uptake (GO:0051580)2.68452655
112ER overload response (GO:0006983)2.67983442
113L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.67308584
114regulation of synapse structural plasticity (GO:0051823)2.66034147
115hindbrain development (GO:0030902)2.65458154
116mannosylation (GO:0097502)2.65337995
117intracellular protein transmembrane import (GO:0044743)2.65238175
118indole-containing compound metabolic process (GO:0042430)2.64811356
119energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.64553622
120ATP hydrolysis coupled proton transport (GO:0015991)2.64553622
121photoreceptor cell maintenance (GO:0045494)2.64475170
122protein localization to synapse (GO:0035418)2.64309834
123antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.63767293
124positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.63167413
125adult feeding behavior (GO:0008343)2.62940608
126neuron fate determination (GO:0048664)2.62147156
127cilium or flagellum-dependent cell motility (GO:0001539)2.61279241
128neuronal action potential (GO:0019228)2.61017211
129phosphatidylinositol acyl-chain remodeling (GO:0036149)2.60871964
130tryptophan metabolic process (GO:0006568)2.60349981
131regulation of rhodopsin mediated signaling pathway (GO:0022400)2.58446032
132dopamine biosynthetic process (GO:0042416)2.56434566
133guanosine-containing compound biosynthetic process (GO:1901070)2.56216465
134synaptic transmission, dopaminergic (GO:0001963)2.54497344
135histone H2A acetylation (GO:0043968)2.53533942
136positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.53221760
137positive regulation of ligase activity (GO:0051351)2.53203247
138kidney morphogenesis (GO:0060993)2.52654389
139protein K6-linked ubiquitination (GO:0085020)2.52522483
140purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.51818027
141regulation of glutamate secretion (GO:0014048)2.51684862
142pyrimidine nucleotide catabolic process (GO:0006244)2.51649600
143RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.51508056
144tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.51508056
145histone arginine methylation (GO:0034969)2.51291295
146positive regulation of synapse assembly (GO:0051965)2.51135817
147regulation of cilium movement (GO:0003352)2.51105016
148positive regulation of mitochondrial fission (GO:0090141)2.50897562
149reflex (GO:0060004)2.50663513
150nephron epithelium morphogenesis (GO:0072088)2.50375861
151nephron tubule morphogenesis (GO:0072078)2.50375861
152startle response (GO:0001964)2.50182073
153C-terminal protein lipidation (GO:0006501)2.49995362
154neuronal action potential propagation (GO:0019227)2.49765678
155substantia nigra development (GO:0021762)2.49320664
156spliceosomal snRNP assembly (GO:0000387)2.48963453
157synaptic transmission, cholinergic (GO:0007271)2.48379568
158adaptation of signaling pathway (GO:0023058)2.48165791
159retinal ganglion cell axon guidance (GO:0031290)2.47592021
160cornea development in camera-type eye (GO:0061303)2.47546612
161polyol catabolic process (GO:0046174)2.44215055
162behavioral response to ethanol (GO:0048149)2.43570990
163proline transport (GO:0015824)2.43207902
164male meiosis I (GO:0007141)2.42827205
165C-terminal protein amino acid modification (GO:0018410)2.42329958
166DNA methylation involved in gamete generation (GO:0043046)2.42229510
167regulation of action potential (GO:0098900)2.42192832
168alanine transport (GO:0032328)2.42165949
169retinal cone cell development (GO:0046549)2.41580124
170endocrine pancreas development (GO:0031018)2.41409851
171regulation of meiosis I (GO:0060631)2.41185578
172C4-dicarboxylate transport (GO:0015740)2.39849336
173positive regulation of meiosis (GO:0045836)2.37979002
174auditory behavior (GO:0031223)2.35856403
175regulation of microtubule-based movement (GO:0060632)2.34192605
176positive regulation of glycolytic process (GO:0045821)2.32053755
177proton transport (GO:0015992)2.31673930

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse4.09573770
2EZH2_22144423_ChIP-Seq_EOC_Human3.84780984
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.70873210
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.39150161
5ZNF274_21170338_ChIP-Seq_K562_Hela3.17609769
6HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.07875211
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.02159483
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.94394085
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.85451951
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.82955090
11TAF15_26573619_Chip-Seq_HEK293_Human2.76262729
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.63036226
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.61115277
14GBX2_23144817_ChIP-Seq_PC3_Human2.59807365
15PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.58128763
16IGF1R_20145208_ChIP-Seq_DFB_Human2.57906937
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.52480533
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.45071949
19MYC_18555785_ChIP-Seq_MESCs_Mouse2.39599171
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.19686443
21FLI1_27457419_Chip-Seq_LIVER_Mouse2.12034297
22THAP11_20581084_ChIP-Seq_MESCs_Mouse2.10418830
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.07462511
24BMI1_23680149_ChIP-Seq_NPCS_Mouse2.05839942
25SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.97891401
26VDR_22108803_ChIP-Seq_LS180_Human1.94935312
27EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.87870887
28DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.76369475
29DCP1A_22483619_ChIP-Seq_HELA_Human1.74455207
30MYC_18358816_ChIP-ChIP_MESCs_Mouse1.73881336
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.73166596
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.71832062
33ELK1_19687146_ChIP-ChIP_HELA_Human1.71700268
34PCGF2_27294783_Chip-Seq_ESCs_Mouse1.70220967
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.70219745
36SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.70076157
37CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.68492564
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66865446
39FUS_26573619_Chip-Seq_HEK293_Human1.66241371
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.66054497
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.66002499
42VDR_23849224_ChIP-Seq_CD4+_Human1.64822534
43* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.62704185
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.61002824
45SMAD4_21799915_ChIP-Seq_A2780_Human1.60471975
46EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.55780799
47SRF_21415370_ChIP-Seq_HL-1_Mouse1.55500025
48* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.54047672
49TTF2_22483619_ChIP-Seq_HELA_Human1.53456070
50* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.50831433
51* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49977712
52TP53_22573176_ChIP-Seq_HFKS_Human1.49462705
53STAT3_23295773_ChIP-Seq_U87_Human1.48244824
54SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47393252
55BCAT_22108803_ChIP-Seq_LS180_Human1.46415471
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44757642
57REST_21632747_ChIP-Seq_MESCs_Mouse1.44531198
58* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.43765151
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.43206341
60* AR_25329375_ChIP-Seq_VCAP_Human1.43173751
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.41462402
62JARID2_20064375_ChIP-Seq_MESCs_Mouse1.40817689
63SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.39556566
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.38220134
65P300_19829295_ChIP-Seq_ESCs_Human1.37614800
66* TCF4_23295773_ChIP-Seq_U87_Human1.37428347
67SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37421571
68EWS_26573619_Chip-Seq_HEK293_Human1.37327716
69MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.37288254
70POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37190001
71FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.36578352
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.36043461
73PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34887352
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.34561843
75EZH2_27304074_Chip-Seq_ESCs_Mouse1.34173277
76EZH2_27294783_Chip-Seq_NPCs_Mouse1.33501949
77IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32989314
78CBP_20019798_ChIP-Seq_JUKART_Human1.32989314
79SOX2_19829295_ChIP-Seq_ESCs_Human1.32909057
80NANOG_19829295_ChIP-Seq_ESCs_Human1.32909057
81SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.32777787
82NR3C1_21868756_ChIP-Seq_MCF10A_Human1.32760919
83FOXA1_27270436_Chip-Seq_PROSTATE_Human1.32729509
84FOXA1_25329375_ChIP-Seq_VCAP_Human1.32729509
85NFE2_27457419_Chip-Seq_LIVER_Mouse1.31374116
86SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.29773768
87GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28787137
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.27349561
89* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27085058
90EED_16625203_ChIP-ChIP_MESCs_Mouse1.26830336
91GABP_19822575_ChIP-Seq_HepG2_Human1.26799320
92MYC_18940864_ChIP-ChIP_HL60_Human1.26329209
93PCGF2_27294783_Chip-Seq_NPCs_Mouse1.26302500
94MYC_19079543_ChIP-ChIP_MESCs_Mouse1.25817288
95RNF2_27304074_Chip-Seq_NSC_Mouse1.25270201
96* TCF4_22108803_ChIP-Seq_LS180_Human1.24355209
97MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.23212780
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23059690
99FOXP3_21729870_ChIP-Seq_TREG_Human1.22184293
100* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21088074
101HTT_18923047_ChIP-ChIP_STHdh_Human1.20310798
102ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.20200257
103EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20112781
104XRN2_22483619_ChIP-Seq_HELA_Human1.20076833
105ELK1_22589737_ChIP-Seq_MCF10A_Human1.19063678
106GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.18661562
107JARID2_20075857_ChIP-Seq_MESCs_Mouse1.18645448
108P53_22387025_ChIP-Seq_ESCs_Mouse1.17944731
109SMAD4_21741376_ChIP-Seq_EPCs_Human1.16594702
110* REST_18959480_ChIP-ChIP_MESCs_Mouse1.15806025
111TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15233622
112RUNX2_22187159_ChIP-Seq_PCA_Human1.14667241
113* CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.12195849
114FOXA1_21572438_ChIP-Seq_LNCaP_Human1.11979017
115NCOR_22424771_ChIP-Seq_293T_Human1.11778256
116ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.11776929
117PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.11637413
118POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11189274
119EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10826098
120HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10526340
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09211475
122CRX_20693478_ChIP-Seq_RETINA_Mouse1.08917696
123TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08792273
124* AR_20517297_ChIP-Seq_VCAP_Human1.08461454
125GATA3_21878914_ChIP-Seq_MCF-7_Human1.08010501
126STAT3_18555785_Chip-Seq_ESCs_Mouse1.07846767
127JUN_21703547_ChIP-Seq_K562_Human1.07314748
128* FLI1_21867929_ChIP-Seq_TH2_Mouse1.06021835
129CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.06005423
130KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05713782
131* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.05445304
132SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.04759543
133ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03992377
134CDX2_22108803_ChIP-Seq_LS180_Human1.02160236
135TAL1_26923725_Chip-Seq_HPCs_Mouse1.02135848
136ERG_21242973_ChIP-ChIP_JURKAT_Human1.02013418
137* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01521045
138NELFA_20434984_ChIP-Seq_ESCs_Mouse1.01413472
139E2F1_18555785_Chip-Seq_ESCs_Mouse1.00956467
140* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99992070
141TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99850850
142PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99435405
143EZH2_18974828_ChIP-Seq_MESCs_Mouse0.99223828
144RNF2_18974828_ChIP-Seq_MESCs_Mouse0.99223828
145POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97623902
146TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97623902
147CMYC_18555785_Chip-Seq_ESCs_Mouse0.97466077
148SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.96946582
149FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.96437985
150HOXB4_20404135_ChIP-ChIP_EML_Mouse0.95964221
151PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94468490
152* ER_23166858_ChIP-Seq_MCF-7_Human0.93868707
153EZH2_27294783_Chip-Seq_ESCs_Mouse0.93178834
154SOX2_16153702_ChIP-ChIP_HESCs_Human0.92080335
155KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91395672
156SOX9_26525672_Chip-Seq_HEART_Mouse0.91064083
157SUZ12_27294783_Chip-Seq_ESCs_Mouse0.91060615
158IRF1_19129219_ChIP-ChIP_H3396_Human0.90241498
159MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.89010380
160MTF2_20144788_ChIP-Seq_MESCs_Mouse0.87153200
161CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.86772918
162MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.86697844
163SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.85898017
164CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.85304390

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.02755064
2MP0001984_abnormal_olfaction3.75684477
3MP0006292_abnormal_olfactory_placode2.95394288
4MP0001529_abnormal_vocalization2.87565201
5MP0001905_abnormal_dopamine_level2.87399775
6MP0006276_abnormal_autonomic_nervous2.64302292
7MP0002102_abnormal_ear_morphology2.60015061
8MP0005645_abnormal_hypothalamus_physiol2.42915516
9MP0003635_abnormal_synaptic_transmissio2.39101772
10MP0002938_white_spotting2.37095671
11MP0003195_calcinosis2.22312529
12MP0002063_abnormal_learning/memory/cond2.20641475
13MP0009745_abnormal_behavioral_response2.18291279
14MP0004270_analgesia2.16931559
15MP0002572_abnormal_emotion/affect_behav2.16808780
16MP0002272_abnormal_nervous_system2.13085519
17MP0002184_abnormal_innervation2.07081085
18MP0002837_dystrophic_cardiac_calcinosis2.06376867
19MP0002064_seizures2.05723834
20MP0002734_abnormal_mechanical_nocicepti2.04179944
21MP0004142_abnormal_muscle_tone1.99280753
22MP0005423_abnormal_somatic_nervous1.97802303
23MP0004859_abnormal_synaptic_plasticity1.94375795
24MP0001968_abnormal_touch/_nociception1.93888375
25MP0005646_abnormal_pituitary_gland1.88053656
26MP0003122_maternal_imprinting1.87992463
27MP0005551_abnormal_eye_electrophysiolog1.85788063
28MP0000778_abnormal_nervous_system1.85371568
29MP0002067_abnormal_sensory_capabilities1.84739183
30MP0002736_abnormal_nociception_after1.82618706
31MP0002822_catalepsy1.82243184
32MP0002653_abnormal_ependyma_morphology1.79261277
33MP0002638_abnormal_pupillary_reflex1.77931604
34MP0000372_irregular_coat_pigmentation1.75220243
35MP0003136_yellow_coat_color1.74106460
36MP0009046_muscle_twitch1.64576891
37MP0002735_abnormal_chemical_nociception1.60834992
38MP0004147_increased_porphyrin_level1.60288418
39MP0003787_abnormal_imprinting1.60165175
40MP0001188_hyperpigmentation1.58840915
41MP0002928_abnormal_bile_duct1.56762579
42MP0004885_abnormal_endolymph1.56338688
43MP0004145_abnormal_muscle_electrophysio1.53355688
44MP0008872_abnormal_physiological_respon1.52729153
45MP0002557_abnormal_social/conspecific_i1.52660627
46MP0001970_abnormal_pain_threshold1.52400192
47MP0009780_abnormal_chondrocyte_physiolo1.51344348
48MP0002733_abnormal_thermal_nociception1.50930121
49MP0001440_abnormal_grooming_behavior1.48602797
50MP0008875_abnormal_xenobiotic_pharmacok1.47673148
51MP0001486_abnormal_startle_reflex1.46298084
52MP0003123_paternal_imprinting1.44492969
53MP0004924_abnormal_behavior1.43706362
54MP0005386_behavior/neurological_phenoty1.43706362
55MP0000569_abnormal_digit_pigmentation1.41618608
56MP0005174_abnormal_tail_pigmentation1.41583037
57MP0008789_abnormal_olfactory_epithelium1.40859334
58MP0005499_abnormal_olfactory_system1.37371308
59MP0005394_taste/olfaction_phenotype1.37371308
60MP0006072_abnormal_retinal_apoptosis1.34704908
61MP0005253_abnormal_eye_physiology1.32981756
62MP0000631_abnormal_neuroendocrine_gland1.32944381
63MP0003329_amyloid_beta_deposits1.28069297
64MP0003879_abnormal_hair_cell1.27440725
65MP0001501_abnormal_sleep_pattern1.27329015
66MP0002876_abnormal_thyroid_physiology1.25880924
67MP0000427_abnormal_hair_cycle1.23469698
68MP0002752_abnormal_somatic_nervous1.23410788
69MP0005389_reproductive_system_phenotype1.21839305
70MP0002882_abnormal_neuron_morphology1.19647541
71MP0005379_endocrine/exocrine_gland_phen1.18965071
72MP0005075_abnormal_melanosome_morpholog1.17486089
73MP0004811_abnormal_neuron_physiology1.16068134
74MP0010386_abnormal_urinary_bladder1.15418133
75MP0003283_abnormal_digestive_organ1.12443653
76MP0002229_neurodegeneration1.11661962
77MP0002751_abnormal_autonomic_nervous1.09962048
78MP0002693_abnormal_pancreas_physiology1.08637940
79MP0001963_abnormal_hearing_physiology1.07941981
80MP0001727_abnormal_embryo_implantation1.07698342
81MP0004133_heterotaxia1.07295659
82MP0002163_abnormal_gland_morphology1.06330699
83MP0002066_abnormal_motor_capabilities/c1.06068984
84MP0005377_hearing/vestibular/ear_phenot1.05381818
85MP0003878_abnormal_ear_physiology1.05381818
86MP0003121_genomic_imprinting1.05048690
87MP0000015_abnormal_ear_pigmentation1.04343624
88MP0001944_abnormal_pancreas_morphology1.03976103
89MP0005171_absent_coat_pigmentation1.03919825
90MP0001986_abnormal_taste_sensitivity1.03054119
91MP0000026_abnormal_inner_ear1.00436946
92MP0002152_abnormal_brain_morphology0.98963153
93MP0000013_abnormal_adipose_tissue0.96408680
94MP0002095_abnormal_skin_pigmentation0.96180278
95MP0003634_abnormal_glial_cell0.95709858
96MP0000049_abnormal_middle_ear0.94947917
97MP0000383_abnormal_hair_follicle0.94107226
98MP0004215_abnormal_myocardial_fiber0.93704087
99MP0000230_abnormal_systemic_arterial0.93366057
100MP0000566_synostosis0.92701771
101MP0006035_abnormal_mitochondrial_morpho0.92635500
102MP0003938_abnormal_ear_development0.92496926
103MP0002160_abnormal_reproductive_system0.92463022
104MP0010329_abnormal_lipoprotein_level0.92318240
105MP0001502_abnormal_circadian_rhythm0.91997269
106MP0000955_abnormal_spinal_cord0.91868791
107MP0009379_abnormal_foot_pigmentation0.91438024
108MP0005410_abnormal_fertilization0.91066761
109MP0005332_abnormal_amino_acid0.90670473
110MP0004742_abnormal_vestibular_system0.90534027
111MP0003718_maternal_effect0.89315644
112MP0002234_abnormal_pharynx_morphology0.89241245
113MP0003890_abnormal_embryonic-extraembry0.89090872
114MP0005220_abnormal_exocrine_pancreas0.88687948
115MP0004858_abnormal_nervous_system0.87777762
116MP0002277_abnormal_respiratory_mucosa0.86522566
117MP0004043_abnormal_pH_regulation0.85616233
118MP0008058_abnormal_DNA_repair0.83570729
119MP0001485_abnormal_pinna_reflex0.82885755
120MP0005084_abnormal_gallbladder_morpholo0.82882414
121MP0003137_abnormal_impulse_conducting0.82559831
122MP0004019_abnormal_vitamin_homeostasis0.82543852
123MP0002909_abnormal_adrenal_gland0.81547740
124MP0001764_abnormal_homeostasis0.81447149
125MP0001324_abnormal_eye_pigmentation0.80885122
126MP0008932_abnormal_embryonic_tissue0.80270864
127MP0002090_abnormal_vision0.78849778
128MP0002233_abnormal_nose_morphology0.78326196
129MP0005195_abnormal_posterior_eye0.76688121
130MP0003011_delayed_dark_adaptation0.76346078
131MP0000751_myopathy0.76332072
132MP0005187_abnormal_penis_morphology0.72877004
133MP0004957_abnormal_blastocyst_morpholog0.72445849
134MP0006036_abnormal_mitochondrial_physio0.70805167
135MP0008877_abnormal_DNA_methylation0.67472029
136MP0003942_abnormal_urinary_system0.64650284
137MP0003631_nervous_system_phenotype0.63784092

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.71913791
2Abnormal mitochondria in muscle tissue (HP:0008316)4.51286725
3Pancreatic fibrosis (HP:0100732)4.24402887
4Mitochondrial inheritance (HP:0001427)4.16393336
5Nephronophthisis (HP:0000090)3.98348823
6Progressive macrocephaly (HP:0004481)3.92805609
7Acute encephalopathy (HP:0006846)3.76960777
8Hepatocellular necrosis (HP:0001404)3.75065645
9Increased CSF lactate (HP:0002490)3.69226808
10Hypothermia (HP:0002045)3.68161188
11Gait imbalance (HP:0002141)3.36960168
12Congenital primary aphakia (HP:0007707)3.33786853
13Large for gestational age (HP:0001520)3.32182197
14Medial flaring of the eyebrow (HP:0010747)3.26993959
15Abnormality of the renal medulla (HP:0100957)3.25827619
16Type II lissencephaly (HP:0007260)3.25125164
17Febrile seizures (HP:0002373)3.22883035
18Decreased activity of mitochondrial respiratory chain (HP:0008972)3.18352425
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.18352425
20Supernumerary spleens (HP:0009799)3.05597230
21True hermaphroditism (HP:0010459)3.00726755
22Congenital stationary night blindness (HP:0007642)2.98715807
23Pancreatic cysts (HP:0001737)2.96849673
24Abnormality of the renal cortex (HP:0011035)2.95470948
25Increased hepatocellular lipid droplets (HP:0006565)2.94413223
26Retinal dysplasia (HP:0007973)2.92371640
27Limb dystonia (HP:0002451)2.92352021
28Optic disc pallor (HP:0000543)2.91213996
29Nephrogenic diabetes insipidus (HP:0009806)2.90727806
30Genital tract atresia (HP:0001827)2.84059156
31Abnormal drinking behavior (HP:0030082)2.82332308
32Polydipsia (HP:0001959)2.82332308
33Abnormal respiratory motile cilium morphology (HP:0005938)2.81006632
34Abnormal respiratory epithelium morphology (HP:0012253)2.81006632
35Chronic hepatic failure (HP:0100626)2.78574732
36Hepatic necrosis (HP:0002605)2.77268332
37Atonic seizures (HP:0010819)2.72865169
38Abnormal ciliary motility (HP:0012262)2.72670974
39Absent/shortened dynein arms (HP:0200106)2.72499813
40Dynein arm defect of respiratory motile cilia (HP:0012255)2.72499813
41Myokymia (HP:0002411)2.68343131
42Respiratory failure (HP:0002878)2.66885324
43Epileptic encephalopathy (HP:0200134)2.65859771
44Vaginal atresia (HP:0000148)2.64557104
45Tubular atrophy (HP:0000092)2.57973930
46Autoamputation (HP:0001218)2.55309378
47Leukodystrophy (HP:0002415)2.55133179
48Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.54064395
49Lactic acidosis (HP:0003128)2.51779636
50Renal Fanconi syndrome (HP:0001994)2.48784380
51Polyphagia (HP:0002591)2.48586297
52Delusions (HP:0000746)2.47496284
53Molar tooth sign on MRI (HP:0002419)2.45413007
54Abnormality of midbrain morphology (HP:0002418)2.45413007
55Neuroendocrine neoplasm (HP:0100634)2.44760881
56Abnormality of the anterior horn cell (HP:0006802)2.44439142
57Degeneration of anterior horn cells (HP:0002398)2.44439142
58Lipid accumulation in hepatocytes (HP:0006561)2.43928136
59Aplasia/Hypoplasia of the lens (HP:0008063)2.42902918
60Poor suck (HP:0002033)2.41091627
61Increased serum lactate (HP:0002151)2.39470469
62Abnormal respiratory motile cilium physiology (HP:0012261)2.37448256
63Truncal ataxia (HP:0002078)2.37133934
64Exercise intolerance (HP:0003546)2.36615366
65Hyperinsulinemic hypoglycemia (HP:0000825)2.36279643
66Increased intramyocellular lipid droplets (HP:0012240)2.32136389
67Pheochromocytoma (HP:0002666)2.31532875
68Increased serum pyruvate (HP:0003542)2.30576974
69Abnormality of glycolysis (HP:0004366)2.30576974
70Furrowed tongue (HP:0000221)2.28350569
71Occipital encephalocele (HP:0002085)2.27877207
72Hemiparesis (HP:0001269)2.27714026
73Congenital hepatic fibrosis (HP:0002612)2.27692636
74Ketoacidosis (HP:0001993)2.27563081
75Focal motor seizures (HP:0011153)2.24663502
76Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.24259901
77Progressive cerebellar ataxia (HP:0002073)2.24051933
78Optic nerve hypoplasia (HP:0000609)2.22452293
79Aplasia/hypoplasia of the uterus (HP:0008684)2.20976531
80Male pseudohermaphroditism (HP:0000037)2.19353313
81Absence seizures (HP:0002121)2.14305644
82Polyuria (HP:0000103)2.12630848
83Abnormal rod and cone electroretinograms (HP:0008323)2.12156366
84Cerebral edema (HP:0002181)2.12010940
85Gaze-evoked nystagmus (HP:0000640)2.11126213
86Poor coordination (HP:0002370)2.10921643
87Postaxial foot polydactyly (HP:0001830)2.10858564
88Hypomagnesemia (HP:0002917)2.09938587
89Hypoglycemic coma (HP:0001325)2.09607354
90Renal cortical cysts (HP:0000803)2.09500821
91Methylmalonic acidemia (HP:0002912)2.08216224
92Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.07759801
93Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.07720144
94Cerebellar dysplasia (HP:0007033)2.06525378
95Pendular nystagmus (HP:0012043)2.02808549
96Esotropia (HP:0000565)2.02380783
97Aplasia of the musculature (HP:0100854)2.01105305
98Abolished electroretinogram (ERG) (HP:0000550)2.00144467
99Abnormality of the pons (HP:0007361)1.96142282
100Decreased circulating renin level (HP:0003351)1.94506041
101Fetal akinesia sequence (HP:0001989)1.93879129
102Lissencephaly (HP:0001339)1.91726521
103Intestinal atresia (HP:0011100)1.90339571
104Cystic liver disease (HP:0006706)1.89540809
105Rhinitis (HP:0012384)1.89258097
106Congenital sensorineural hearing impairment (HP:0008527)1.89158574
107Abnormality of the labia minora (HP:0012880)1.88865059
108Ketosis (HP:0001946)1.88770195
109Congenital, generalized hypertrichosis (HP:0004540)1.88318111
110Spinal muscular atrophy (HP:0007269)1.88282237
111Aplasia/Hypoplasia of the tongue (HP:0010295)1.87719528
112Microvesicular hepatic steatosis (HP:0001414)1.87654251
113Aplasia/Hypoplasia of the tibia (HP:0005772)1.86656661
114Hypoplasia of the fovea (HP:0007750)1.86408732
115Aplasia/Hypoplasia of the fovea (HP:0008060)1.86408732
116Visual hallucinations (HP:0002367)1.84508993
117Keratoconus (HP:0000563)1.82395459
118Increased corneal curvature (HP:0100692)1.82395459
1193-Methylglutaconic aciduria (HP:0003535)1.82347423
120Epileptiform EEG discharges (HP:0011182)1.81106486
121Emotional lability (HP:0000712)1.80146746
122Bifid tongue (HP:0010297)1.76579468
123Median cleft lip (HP:0000161)1.76115656
124Broad-based gait (HP:0002136)1.76049905
125Glycosuria (HP:0003076)1.75834848
126Abnormality of urine glucose concentration (HP:0011016)1.75834848
127Abnormal biliary tract physiology (HP:0012439)1.75494741
128Bile duct proliferation (HP:0001408)1.75494741
129Atrophy/Degeneration involving motor neurons (HP:0007373)1.75127048
130Sclerocornea (HP:0000647)1.74597773
131Broad foot (HP:0001769)1.74519529
132Inability to walk (HP:0002540)1.74472905
133Abnormality of macular pigmentation (HP:0008002)1.74429422
134Abnormality of the fovea (HP:0000493)1.73946951
135Abnormality of alanine metabolism (HP:0010916)1.72764847
136Hyperalaninemia (HP:0003348)1.72764847
137Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.72764847
138Postaxial hand polydactyly (HP:0001162)1.71721407
139Dialeptic seizures (HP:0011146)1.71648362
140Cerebral hypomyelination (HP:0006808)1.70499724
141Attenuation of retinal blood vessels (HP:0007843)1.70384268
142Abnormality of pain sensation (HP:0010832)1.70011726
143Impaired pain sensation (HP:0007328)1.70011726
144Hypsarrhythmia (HP:0002521)1.69363719
145Anxiety (HP:0000739)1.69223507
146Anencephaly (HP:0002323)1.68030327
147Short tibia (HP:0005736)1.67873414
148Respiratory difficulties (HP:0002880)1.67629738
149Increased muscle lipid content (HP:0009058)1.67104128
150EEG with generalized epileptiform discharges (HP:0011198)1.65299460
151Abnormality of cells of the erythroid lineage (HP:0012130)1.65199045
152Bony spicule pigmentary retinopathy (HP:0007737)1.64845997
153Parakeratosis (HP:0001036)1.63687241
154Hyperventilation (HP:0002883)1.61560005

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.82052284
2CASK4.48175451
3MAP4K23.31341979
4CAMKK23.07517946
5WNK32.70772702
6PLK22.66867714
7VRK12.66271105
8TSSK62.52298995
9PINK12.52192109
10EPHA42.44869801
11BUB12.44429981
12ARAF2.41216698
13MAP3K122.37911491
14ZAK2.14688847
15STK162.03438333
16DAPK11.99307395
17WNK41.98970293
18NME11.96934353
19AKT31.92627532
20TRIM281.86312131
21NUAK11.80949415
22TLK11.73024417
23ACVR1B1.72661157
24PLK31.71752183
25TAOK31.68725105
26DAPK21.67280892
27MAP2K71.66522634
28GRK51.64991145
29MAPKAPK51.62572720
30PNCK1.62074507
31MINK11.60208629
32MST41.57403261
33MARK11.56299773
34MAPK131.55036773
35SIK31.51154620
36BRAF1.49125848
37NTRK31.48868583
38BRSK21.47981211
39CSNK1G21.44548763
40CAMK2B1.43878556
41TESK21.43802626
42PAK31.38359969
43FGFR21.37611060
44INSRR1.34262170
45WEE11.33920728
46BCKDK1.31342986
47CDK191.30818726
48BCR1.28420191
49STK38L1.28202639
50PTK2B1.21513528
51STK391.20733134
52DYRK21.18165448
53CDK81.17131168
54TNIK1.12063617
55YES11.03838409
56MAP3K41.03215245
57UHMK10.99954568
58CAMK2D0.98019700
59PRKCG0.95220479
60CSNK1A1L0.93625981
61BMPR1B0.92731449
62PLK40.92200429
63MAP3K90.90799894
64NTRK10.89800075
65OXSR10.89294540
66MAPK150.89097359
67AURKA0.88465133
68CAMK2A0.87438679
69IRAK20.86067054
70TIE10.85431099
71CDK180.83205925
72CCNB10.79522263
73STK30.78818079
74CDK140.78176919
75CAMK2G0.77877444
76MAP2K60.77234351
77BMPR20.76932334
78MKNK20.75678782
79CDK150.74793673
80EIF2AK10.74330387
81PDK20.74023309
82CAMKK10.72829732
83MOS0.72823032
84PHKG20.72597078
85PHKG10.72597078
86SGK4940.71623711
87SGK2230.71623711
88DYRK1A0.71375973
89ERBB30.69775066
90EIF2AK30.69430098
91TGFBR10.69065824
92ADRBK20.68438698
93PRKCI0.66904264
94CDK11A0.66722154
95PASK0.66506225
96CDK50.65509876
97CSNK1G30.64052027
98MKNK10.64016298
99CSNK1A10.63083185
100ADRBK10.62919753
101GRK70.62637081
102NEK60.61844742
103NTRK20.61358809
104SRPK10.59762704
105LIMK10.59193718
106ROCK20.58839787
107FGR0.58786499
108MUSK0.57986673
109CSNK2A10.57366656
110DAPK30.55626875
111NME20.54184015
112GRK10.52326449
113PAK60.51750817
114STK240.50927379
115CSNK2A20.50885598
116MAPKAPK30.50133735
117CAMK10.49954875
118CDK30.49546395
119NLK0.49289613
120PRKCE0.48973143
121STK110.47694295
122BRSK10.47103002
123CSNK1G10.46853484
124SCYL20.46770703
125SGK20.45484392
126FER0.44698770
127FLT30.44521687
128PRKG10.44441798
129IKBKB0.44437445
130CSNK1D0.43336374
131RPS6KA50.43094226
132PRKCA0.42950405
133TNK20.42883174
134RPS6KB10.42829376
135EPHA30.42335368
136PRKACA0.41767722
137DYRK30.41048380
138PRKCQ0.40109808
139MAP2K40.38155822
140OBSCN0.38133397
141RPS6KA20.37836367
142PRPF4B0.36877094
143VRK20.35476996
144PRKCZ0.32232218
145PRKACB0.31964253
146PLK10.30866702

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.26051133
2Proteasome_Homo sapiens_hsa030504.12968935
3Parkinsons disease_Homo sapiens_hsa050123.71617963
4RNA polymerase_Homo sapiens_hsa030202.86415082
5Alzheimers disease_Homo sapiens_hsa050102.77749265
6Huntingtons disease_Homo sapiens_hsa050162.75088368
7Ribosome_Homo sapiens_hsa030102.73800355
8Nicotine addiction_Homo sapiens_hsa050332.66005553
9Protein export_Homo sapiens_hsa030602.60513043
10Olfactory transduction_Homo sapiens_hsa047402.55587094
11Phototransduction_Homo sapiens_hsa047442.24178704
12Nitrogen metabolism_Homo sapiens_hsa009102.13111508
13Butanoate metabolism_Homo sapiens_hsa006502.11647903
14Collecting duct acid secretion_Homo sapiens_hsa049662.06232467
15Synaptic vesicle cycle_Homo sapiens_hsa047212.02862334
16Tryptophan metabolism_Homo sapiens_hsa003801.78334808
17Serotonergic synapse_Homo sapiens_hsa047261.75311783
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.74953502
19GABAergic synapse_Homo sapiens_hsa047271.72662150
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.70347892
21Vibrio cholerae infection_Homo sapiens_hsa051101.69083094
22Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.64464824
23Pyrimidine metabolism_Homo sapiens_hsa002401.64121877
24DNA replication_Homo sapiens_hsa030301.59102923
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.59053395
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.57009054
27Spliceosome_Homo sapiens_hsa030401.47517270
28Cardiac muscle contraction_Homo sapiens_hsa042601.47216622
29Taste transduction_Homo sapiens_hsa047421.45058625
30Selenocompound metabolism_Homo sapiens_hsa004501.43142847
31Fatty acid elongation_Homo sapiens_hsa000621.42667512
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.42138186
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41875520
34Caffeine metabolism_Homo sapiens_hsa002321.37120411
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.35837411
36Morphine addiction_Homo sapiens_hsa050321.34420973
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33161158
38Dopaminergic synapse_Homo sapiens_hsa047281.29011651
39Primary bile acid biosynthesis_Homo sapiens_hsa001201.25448678
40Circadian entrainment_Homo sapiens_hsa047131.23631682
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23358361
42Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.22829476
43Purine metabolism_Homo sapiens_hsa002301.22575802
44Mismatch repair_Homo sapiens_hsa034301.22039283
45Glutamatergic synapse_Homo sapiens_hsa047241.15744344
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14832357
47Amphetamine addiction_Homo sapiens_hsa050311.14767964
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.13355789
49Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.12865243
50Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.12203560
51Peroxisome_Homo sapiens_hsa041461.11621370
52Nucleotide excision repair_Homo sapiens_hsa034201.10980905
53ABC transporters_Homo sapiens_hsa020101.09876021
54Chemical carcinogenesis_Homo sapiens_hsa052041.09717603
55RNA transport_Homo sapiens_hsa030131.06896522
56beta-Alanine metabolism_Homo sapiens_hsa004101.06525479
57Long-term potentiation_Homo sapiens_hsa047201.04485172
58Steroid biosynthesis_Homo sapiens_hsa001001.03863889
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.02543839
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.98299168
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.97769182
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94876209
63Base excision repair_Homo sapiens_hsa034100.94192324
64Retinol metabolism_Homo sapiens_hsa008300.90793436
65Steroid hormone biosynthesis_Homo sapiens_hsa001400.90165890
66Pentose and glucuronate interconversions_Homo sapiens_hsa000400.87615988
67Homologous recombination_Homo sapiens_hsa034400.84807335
68Pyruvate metabolism_Homo sapiens_hsa006200.83410241
69Folate biosynthesis_Homo sapiens_hsa007900.83263786
70Cocaine addiction_Homo sapiens_hsa050300.81680153
71Basal transcription factors_Homo sapiens_hsa030220.79847496
72Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.77337035
73Cholinergic synapse_Homo sapiens_hsa047250.76624371
74Alcoholism_Homo sapiens_hsa050340.75607197
75Insulin secretion_Homo sapiens_hsa049110.73486728
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.72389876
77Mineral absorption_Homo sapiens_hsa049780.66628267
78N-Glycan biosynthesis_Homo sapiens_hsa005100.66193339
79Metabolic pathways_Homo sapiens_hsa011000.65898482
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63673180
81Calcium signaling pathway_Homo sapiens_hsa040200.63617358
82RNA degradation_Homo sapiens_hsa030180.62725499
83Salivary secretion_Homo sapiens_hsa049700.62312310
84Histidine metabolism_Homo sapiens_hsa003400.61894630
85Oocyte meiosis_Homo sapiens_hsa041140.61748252
86Ovarian steroidogenesis_Homo sapiens_hsa049130.60640179
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60579542
88One carbon pool by folate_Homo sapiens_hsa006700.60493728
89Long-term depression_Homo sapiens_hsa047300.60469807
90Fat digestion and absorption_Homo sapiens_hsa049750.59637481
91Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58616852
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.57649966
93Glutathione metabolism_Homo sapiens_hsa004800.56575663
94Fatty acid degradation_Homo sapiens_hsa000710.53461124
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52957655
96Glycerolipid metabolism_Homo sapiens_hsa005610.51536010
97Renin secretion_Homo sapiens_hsa049240.51523785
98Gap junction_Homo sapiens_hsa045400.50385824
99Phagosome_Homo sapiens_hsa041450.49883305
100Hedgehog signaling pathway_Homo sapiens_hsa043400.49579843
101Sulfur metabolism_Homo sapiens_hsa009200.49288993
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.49067909
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46991207
104Arachidonic acid metabolism_Homo sapiens_hsa005900.46534710
105Ether lipid metabolism_Homo sapiens_hsa005650.45467705
106Cell cycle_Homo sapiens_hsa041100.44481188
107Type I diabetes mellitus_Homo sapiens_hsa049400.44071610
108Epstein-Barr virus infection_Homo sapiens_hsa051690.42035025
109Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41419248
110Fatty acid metabolism_Homo sapiens_hsa012120.40558912
111Sulfur relay system_Homo sapiens_hsa041220.38674449
112alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37467404
113Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.36942377
114Sphingolipid metabolism_Homo sapiens_hsa006000.36292043
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.35547918
116Non-homologous end-joining_Homo sapiens_hsa034500.35073738
117Oxytocin signaling pathway_Homo sapiens_hsa049210.33734818
118Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.33135161
119Arginine and proline metabolism_Homo sapiens_hsa003300.32614040
120Tyrosine metabolism_Homo sapiens_hsa003500.31985952
121Prion diseases_Homo sapiens_hsa050200.31572416
122Linoleic acid metabolism_Homo sapiens_hsa005910.29450548
123Aldosterone synthesis and secretion_Homo sapiens_hsa049250.29110917
124Fanconi anemia pathway_Homo sapiens_hsa034600.29025227
125Phenylalanine metabolism_Homo sapiens_hsa003600.28966855
126Gastric acid secretion_Homo sapiens_hsa049710.28678124
127Axon guidance_Homo sapiens_hsa043600.27982562
128Rheumatoid arthritis_Homo sapiens_hsa053230.26490420
129Propanoate metabolism_Homo sapiens_hsa006400.24749711
130Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.22502937
131Regulation of autophagy_Homo sapiens_hsa041400.21320800
132Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.20666061
133Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.19823597
134Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.19266475
135Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.15997254
136Circadian rhythm_Homo sapiens_hsa047100.15501439

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »