TMEM170B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)6.01724251
2neurotransmitter-gated ion channel clustering (GO:0072578)5.93663410
3presynaptic membrane organization (GO:0097090)5.35608854
4regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)5.20389310
5postsynaptic membrane organization (GO:0001941)5.16900478
6neuron cell-cell adhesion (GO:0007158)5.06543429
7response to peptidoglycan (GO:0032494)5.02093504
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.86765857
9cellular extravasation (GO:0045123)4.82589158
10positive regulation of gamma-delta T cell activation (GO:0046645)4.78288414
11vocalization behavior (GO:0071625)4.74506308
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.60129043
13modulation by symbiont of host immune response (GO:0052553)4.60129043
14positive regulation by symbiont of host defense response (GO:0052509)4.60129043
15modulation by symbiont of host defense response (GO:0052031)4.60129043
16modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.60129043
17modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.60129043
18positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.59254067
19detection of molecule of bacterial origin (GO:0032490)4.56010649
20protein localization to synapse (GO:0035418)4.53022576
21synaptic vesicle exocytosis (GO:0016079)4.51596698
22synaptic vesicle docking involved in exocytosis (GO:0016081)4.43069905
23microglial cell activation (GO:0001774)4.34159063
24regulation of glutamate receptor signaling pathway (GO:1900449)4.32758459
25neutrophil activation involved in immune response (GO:0002283)4.31260380
26detection of other organism (GO:0098543)4.27202042
27neutrophil mediated immunity (GO:0002446)4.26685901
28positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.26570335
29regulation of synaptic vesicle exocytosis (GO:2000300)4.26249444
30positive regulation of mast cell activation (GO:0033005)4.22817084
31negative regulation of synaptic transmission, GABAergic (GO:0032229)4.17020139
32activated T cell proliferation (GO:0050798)4.15712158
33negative regulation of cell killing (GO:0031342)4.08728318
34negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.08728318
35macrophage activation involved in immune response (GO:0002281)4.08311120
36cerebellar granule cell differentiation (GO:0021707)4.05116500
37regulation of short-term neuronal synaptic plasticity (GO:0048172)3.97843282
38regulation of synaptic vesicle transport (GO:1902803)3.97339000
39ionotropic glutamate receptor signaling pathway (GO:0035235)3.87238351
40mechanosensory behavior (GO:0007638)3.85085927
41glutamate secretion (GO:0014047)3.79076208
42macrophage activation (GO:0042116)3.77867099
43startle response (GO:0001964)3.76628633
44myeloid leukocyte mediated immunity (GO:0002444)3.75460166
45detection of external biotic stimulus (GO:0098581)3.73223339
46synaptic transmission, glutamatergic (GO:0035249)3.71483314
47pyrimidine nucleobase catabolic process (GO:0006208)3.68580999
48neuron-neuron synaptic transmission (GO:0007270)3.67722791
49glutamate receptor signaling pathway (GO:0007215)3.66821597
50detection of bacterium (GO:0016045)3.66037226
51detection of biotic stimulus (GO:0009595)3.64781700
52neuronal action potential propagation (GO:0019227)3.55102177
53positive regulation of mast cell degranulation (GO:0043306)3.47887687
54positive regulation of mast cell activation involved in immune response (GO:0033008)3.47887687
55regulation of mast cell activation (GO:0033003)3.46052150
56regulation of B cell receptor signaling pathway (GO:0050855)3.44766749
57response to muramyl dipeptide (GO:0032495)3.43956331
58membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.43777634
59positive regulation of cellular amide metabolic process (GO:0034250)3.39710463
60response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.38500641
61response to host immune response (GO:0052572)3.38500641
62leukocyte migration involved in inflammatory response (GO:0002523)3.37529578
63negative regulation of interleukin-12 production (GO:0032695)3.37363032
64negative regulation of dendrite morphogenesis (GO:0050774)3.36393964
65auditory behavior (GO:0031223)3.35424064
66gamma-aminobutyric acid signaling pathway (GO:0007214)3.34654413
67neurotransmitter secretion (GO:0007269)3.31639722
68regulation of gamma-delta T cell activation (GO:0046643)3.30960386
69regulation of excitatory postsynaptic membrane potential (GO:0060079)3.29840518
70negative regulation of lymphocyte mediated immunity (GO:0002707)3.28788430
71synapse assembly (GO:0007416)3.26576779
72cell wall macromolecule catabolic process (GO:0016998)3.26327546
73regulation of synaptic transmission, glutamatergic (GO:0051966)3.25162034
74long-term synaptic potentiation (GO:0060291)3.23928392
75neutrophil activation (GO:0042119)3.23852007
76negative regulation of T cell mediated immunity (GO:0002710)3.22222990
77positive regulation of membrane potential (GO:0045838)3.21037424
78cerebral cortex radially oriented cell migration (GO:0021799)3.20077779
79locomotory exploration behavior (GO:0035641)3.18771003
80positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.17168370
81gamma-aminobutyric acid transport (GO:0015812)3.17075819
82regulation of glutamate secretion (GO:0014048)3.16245809
83negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.15394828
84nucleobase catabolic process (GO:0046113)3.14567503
85negative regulation of dendrite development (GO:2000171)3.13157435
86regulation of mast cell degranulation (GO:0043304)3.12226877
87positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.12109786
88response to histamine (GO:0034776)3.11721581
89regulation of postsynaptic membrane potential (GO:0060078)3.09916865
90antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.09657577
91respiratory burst (GO:0045730)3.09451346
92synaptic vesicle maturation (GO:0016188)3.08842783
93regulation of neurotransmitter secretion (GO:0046928)3.07156387
94positive regulation of synapse assembly (GO:0051965)3.04254209
95G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.04202017
96regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.03966528
97synaptic vesicle endocytosis (GO:0048488)3.03838190
98regulation of long-term neuronal synaptic plasticity (GO:0048169)3.03142964
99regulation of synapse maturation (GO:0090128)3.02083360
100response to auditory stimulus (GO:0010996)3.01649933
101regulation of mast cell activation involved in immune response (GO:0033006)3.01609394
102cerebellar Purkinje cell differentiation (GO:0021702)3.01156193
103myeloid cell activation involved in immune response (GO:0002275)2.99839143
104negative regulation of neurotransmitter transport (GO:0051589)2.99830024
105regulation of neuronal synaptic plasticity (GO:0048168)2.99499344
106regulation of regulated secretory pathway (GO:1903305)2.98969083
107inositol phosphate catabolic process (GO:0071545)2.98470250
108positive regulation of neurotransmitter secretion (GO:0001956)2.97891050
109regulation of synapse structural plasticity (GO:0051823)2.95718143
110regulation of leukocyte degranulation (GO:0043300)2.95350500
111positive regulation of synapse maturation (GO:0090129)2.94391977
112phagosome maturation (GO:0090382)2.94296213
113response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.94243727
114response to host (GO:0075136)2.94243727
115response to host defenses (GO:0052200)2.94243727
116regulation of myeloid leukocyte mediated immunity (GO:0002886)2.93820780
117long-term memory (GO:0007616)2.92322132
118negative regulation of erythrocyte differentiation (GO:0045647)2.90766942
119neuron recognition (GO:0008038)2.90732190
120nerve growth factor signaling pathway (GO:0038180)2.89736024
121dendrite development (GO:0016358)2.87189848
122dentate gyrus development (GO:0021542)2.82992840
123granulocyte activation (GO:0036230)2.82175215
124cAMP catabolic process (GO:0006198)2.81530573
125regulation of macrophage cytokine production (GO:0010935)2.81487247
126neurotransmitter uptake (GO:0001504)2.78135966
127neurotransmitter transport (GO:0006836)2.77796653
128exploration behavior (GO:0035640)2.77743015
129regulation of interferon-beta biosynthetic process (GO:0045357)2.77306044
130regulation of neurotransmitter transport (GO:0051588)2.76709165
131regulation of female receptivity (GO:0045924)2.74437541
132regulation of synaptic plasticity (GO:0048167)2.74344132
133positive regulation of neurotransmitter transport (GO:0051590)2.74236578
134regulation of synaptic transmission, GABAergic (GO:0032228)2.73958198
135positive regulation of regulated secretory pathway (GO:1903307)2.70467415
136learning (GO:0007612)2.70436763
137transferrin transport (GO:0033572)2.69826443
138positive regulation of leukocyte degranulation (GO:0043302)2.68815851
139membrane assembly (GO:0071709)2.68025086
140regulation of ARF protein signal transduction (GO:0032012)2.66928381
141negative regulation of B cell mediated immunity (GO:0002713)2.65887387
142negative regulation of immunoglobulin mediated immune response (GO:0002890)2.65887387
143positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.65628933
144positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.63851549
145negative regulation of interleukin-1 beta production (GO:0032691)2.63333901
146negative regulation of leukocyte mediated immunity (GO:0002704)2.63085949
147regulation of interleukin-8 biosynthetic process (GO:0045414)2.62202181
148regulation of synapse assembly (GO:0051963)2.62082211
149positive regulation of macrophage cytokine production (GO:0060907)2.61688751
150membrane depolarization (GO:0051899)2.61013825
151regulation of amino acid transport (GO:0051955)2.60091816
152female mating behavior (GO:0060180)2.59572898
153negative regulation of neurotransmitter secretion (GO:0046929)2.59544428
154positive regulation of synaptic transmission (GO:0050806)2.59284195
155proline transport (GO:0015824)2.58629156
156regulation of beta-amyloid formation (GO:1902003)2.58228424
157establishment of synaptic vesicle localization (GO:0097480)2.57741530
158synaptic vesicle transport (GO:0048489)2.57741530
159central nervous system projection neuron axonogenesis (GO:0021952)2.55807711
160neutrophil chemotaxis (GO:0030593)2.54778537
161killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.54622516
162disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.54622516
163positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.54061993
164cell wall macromolecule metabolic process (GO:0044036)2.54025487
165regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.53859577
166regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.53834640
167cyclic nucleotide catabolic process (GO:0009214)2.52676944
168negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.52643704
169negative regulation of interleukin-1 production (GO:0032692)2.52517250
170G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.52213775
171phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.50346282
172neutrophil migration (GO:1990266)2.48352388
173axonal fasciculation (GO:0007413)2.47789362
174regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.47714426
175regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.46933248
176positive regulation of amino acid transport (GO:0051957)2.46372965
177L-amino acid import (GO:0043092)2.45820350
178regulation of neurotransmitter levels (GO:0001505)2.45746443
179behavioral response to cocaine (GO:0048148)2.45365030
180ferric iron transport (GO:0015682)2.45235265
181trivalent inorganic cation transport (GO:0072512)2.45235265

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.50697568
2GBX2_23144817_ChIP-Seq_PC3_Human4.49704385
3ZFP57_27257070_Chip-Seq_ESCs_Mouse2.61465879
4TAF15_26573619_Chip-Seq_HEK293_Human2.59667933
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.50031549
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.44470202
7BP1_19119308_ChIP-ChIP_Hs578T_Human2.41493050
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.39659577
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.35634072
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.35234066
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.33030959
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.22912072
13IRF8_21731497_ChIP-ChIP_J774_Mouse2.20040769
14CTBP2_25329375_ChIP-Seq_LNCAP_Human2.19957377
15P300_19829295_ChIP-Seq_ESCs_Human2.18611676
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.13642077
17* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.07335975
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.05543411
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.03816235
20STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.03337969
21REST_21632747_ChIP-Seq_MESCs_Mouse2.02476355
22SMAD4_21799915_ChIP-Seq_A2780_Human2.00974027
23* IRF8_27001747_Chip-Seq_BMDM_Mouse1.99322555
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.96435318
25EED_16625203_ChIP-ChIP_MESCs_Mouse1.93146707
26PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.92556391
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.92343440
28JARID2_20075857_ChIP-Seq_MESCs_Mouse1.91102509
29VDR_24787735_ChIP-Seq_THP-1_Human1.90037274
30SMAD_19615063_ChIP-ChIP_OVARY_Human1.88856850
31RNF2_18974828_ChIP-Seq_MESCs_Mouse1.88679051
32EZH2_18974828_ChIP-Seq_MESCs_Mouse1.88679051
33SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.86489815
34AR_21572438_ChIP-Seq_LNCaP_Human1.82229622
35MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.78156219
36* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.75735707
37CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.72852085
38CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.71932818
39MTF2_20144788_ChIP-Seq_MESCs_Mouse1.69665671
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.68540363
41STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.68293396
42SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.67158057
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.67095009
44* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64785678
45MYB_21317192_ChIP-Seq_ERMYB_Mouse1.64149801
46Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.63847502
47IRF8_22096565_ChIP-ChIP_GC-B_Human1.62805078
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.62675231
49* SMAD3_21741376_ChIP-Seq_EPCs_Human1.62654852
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.61889757
51RUNX_20019798_ChIP-Seq_JUKART_Human1.60414145
52EZH2_27294783_Chip-Seq_ESCs_Mouse1.60056266
53FUS_26573619_Chip-Seq_HEK293_Human1.60035095
54REST_18959480_ChIP-ChIP_MESCs_Mouse1.59547535
55ER_23166858_ChIP-Seq_MCF-7_Human1.58631332
56SCL_19346495_ChIP-Seq_HPC-7_Human1.56547725
57IGF1R_20145208_ChIP-Seq_DFB_Human1.55818652
58FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.55570303
59* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.53967384
60SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52120391
61DROSHA_22980978_ChIP-Seq_HELA_Human1.51533703
62BMI1_23680149_ChIP-Seq_NPCS_Mouse1.51042712
63* AR_25329375_ChIP-Seq_VCAP_Human1.50450791
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48122318
65FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.47300985
66* PIAS1_25552417_ChIP-Seq_VCAP_Human1.46197388
67NANOG_18555785_Chip-Seq_ESCs_Mouse1.45217831
68RARB_27405468_Chip-Seq_BRAIN_Mouse1.44765132
69RNF2_27304074_Chip-Seq_NSC_Mouse1.42541708
70* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42328955
71FLI1_27457419_Chip-Seq_LIVER_Mouse1.39566590
72* STAT3_23295773_ChIP-Seq_U87_Human1.38732947
73PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.38163902
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.38154914
75VDR_24763502_ChIP-Seq_THP-1_Human1.37652886
76UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.37202785
77E2F1_18555785_Chip-Seq_ESCs_Mouse1.37080353
78PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.35871331
79* PRDM14_20953172_ChIP-Seq_ESCs_Human1.35174098
80* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.35137310
81TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34035242
82POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34035242
83MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33962789
84P53_22387025_ChIP-Seq_ESCs_Mouse1.33950718
85BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.33620473
86VDR_22108803_ChIP-Seq_LS180_Human1.33591586
87EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.33569818
88TCF4_23295773_ChIP-Seq_U87_Human1.32634082
89PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32211906
90SOX2_21211035_ChIP-Seq_LN229_Gbm1.32141155
91RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31118780
92SUZ12_18555785_Chip-Seq_ESCs_Mouse1.30749925
93ARNT_22903824_ChIP-Seq_MCF-7_Human1.30154111
94RBPJ_22232070_ChIP-Seq_NCS_Mouse1.29200030
95CMYC_18555785_Chip-Seq_ESCs_Mouse1.28374780
96SPI1_23127762_ChIP-Seq_K562_Human1.27559446
97IKZF1_21737484_ChIP-ChIP_HCT116_Human1.26360394
98EWS_26573619_Chip-Seq_HEK293_Human1.24938470
99TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23913989
100SUZ12_27294783_Chip-Seq_NPCs_Mouse1.23836097
101* RUNX2_22187159_ChIP-Seq_PCA_Human1.23697516
102ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.21190231
103CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20334761
104STAT3_18555785_Chip-Seq_ESCs_Mouse1.18793423
105AHR_22903824_ChIP-Seq_MCF-7_Human1.18693979
106FLI1_21867929_ChIP-Seq_TH2_Mouse1.18568857
107SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18322148
108P300_18555785_Chip-Seq_ESCs_Mouse1.18227755
109EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.17948660
110CDX2_19796622_ChIP-Seq_MESCs_Mouse1.16616350
111TP53_18474530_ChIP-ChIP_U2OS_Human1.16478585
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.16183192
113TAL1_26923725_Chip-Seq_HPCs_Mouse1.14527787
114SOX2_18555785_Chip-Seq_ESCs_Mouse1.14321631
115RUNX1_27457419_Chip-Seq_LIVER_Mouse1.14308263
116* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10804245
117NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10264252
118ZNF217_24962896_ChIP-Seq_MCF-7_Human1.09798633
119KDM2B_26808549_Chip-Seq_REH_Human1.08739056
120P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08172382
121NMYC_18555785_Chip-Seq_ESCs_Mouse1.06845833
122PU1_27457419_Chip-Seq_LIVER_Mouse1.06538743
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05925927
124GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05793982
125NFE2_27457419_Chip-Seq_LIVER_Mouse1.05448553
126TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.04555808
127VDR_21846776_ChIP-Seq_THP-1_Human1.03551848
128CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.01487358
129EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00348800
130SALL1_21062744_ChIP-ChIP_HESCs_Human0.99229705
131KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98836024
132BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97780591
133WT1_25993318_ChIP-Seq_PODOCYTE_Human0.97447136
134TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.93763371
135LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91891721
136* PU_27001747_Chip-Seq_BMDM_Mouse0.91453342
137RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.91087356
138SPI1_23547873_ChIP-Seq_NB4_Human0.89932736
139PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89539368
140AR_19668381_ChIP-Seq_PC3_Human0.89381894
141EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89012081

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.57619028
2MP0004859_abnormal_synaptic_plasticity4.38527092
3MP0003635_abnormal_synaptic_transmissio3.42629306
4MP0009745_abnormal_behavioral_response3.10512542
5MP0001188_hyperpigmentation3.02242550
6MP0009046_muscle_twitch2.97937491
7MP0001968_abnormal_touch/_nociception2.96184667
8MP0002063_abnormal_learning/memory/cond2.94678530
9MP0002064_seizures2.84988836
10MP0004270_analgesia2.84657871
11MP0002572_abnormal_emotion/affect_behav2.61957284
12MP0002009_preneoplasia2.59770235
13MP0002736_abnormal_nociception_after2.56626192
14MP0002735_abnormal_chemical_nociception2.55898985
15MP0003787_abnormal_imprinting2.45289529
16MP0005646_abnormal_pituitary_gland2.45046664
17MP0001486_abnormal_startle_reflex2.40868672
18MP0002734_abnormal_mechanical_nocicepti2.35178577
19MP0002272_abnormal_nervous_system2.26650208
20MP0005423_abnormal_somatic_nervous2.25187823
21MP0005409_darkened_coat_color2.23889586
22MP0003183_abnormal_peptide_metabolism2.15361600
23MP0000778_abnormal_nervous_system2.13635122
24MP0004130_abnormal_muscle_cell2.11115439
25MP0005645_abnormal_hypothalamus_physiol2.10382106
26MP0003436_decreased_susceptibility_to2.05464629
27MP0002067_abnormal_sensory_capabilities2.04591656
28MP0003828_pulmonary_edema1.97122756
29MP0001984_abnormal_olfaction1.92376479
30MP0000015_abnormal_ear_pigmentation1.88141400
31MP0002876_abnormal_thyroid_physiology1.81869784
32MP0002822_catalepsy1.77933907
33MP0002733_abnormal_thermal_nociception1.72548263
34MP0006276_abnormal_autonomic_nervous1.70576493
35MP0001970_abnormal_pain_threshold1.69319832
36MP0002557_abnormal_social/conspecific_i1.67189899
37MP0001501_abnormal_sleep_pattern1.66551031
38MP0008569_lethality_at_weaning1.62182729
39MP0002184_abnormal_innervation1.61822422
40MP0004924_abnormal_behavior1.61692761
41MP0005386_behavior/neurological_phenoty1.61692761
42MP0005551_abnormal_eye_electrophysiolog1.61022534
43MP0001440_abnormal_grooming_behavior1.59218017
44MP0001986_abnormal_taste_sensitivity1.56401355
45MP0001502_abnormal_circadian_rhythm1.52298299
46MP0004142_abnormal_muscle_tone1.51482527
47MP0003879_abnormal_hair_cell1.46906219
48MP0001905_abnormal_dopamine_level1.46491489
49MP0006082_CNS_inflammation1.46293363
50MP0009780_abnormal_chondrocyte_physiolo1.45965269
51MP0003136_yellow_coat_color1.45234708
52MP0004811_abnormal_neuron_physiology1.44393634
53MP0005171_absent_coat_pigmentation1.43164654
54MP0001800_abnormal_humoral_immune1.41091901
55MP0001529_abnormal_vocalization1.40108763
56MP0005025_abnormal_response_to1.40094679
57MP0000685_abnormal_immune_system1.33848239
58MP0000604_amyloidosis1.33446387
59MP0002882_abnormal_neuron_morphology1.26666773
60MP0003690_abnormal_glial_cell1.24631517
61MP0002420_abnormal_adaptive_immunity1.23688180
62MP0003633_abnormal_nervous_system1.22544353
63MP0001819_abnormal_immune_cell1.20104875
64MP0004742_abnormal_vestibular_system1.19630208
65MP0002452_abnormal_antigen_presenting1.17942402
66MP0005000_abnormal_immune_tolerance1.17668868
67MP0002723_abnormal_immune_serum1.17565313
68MP0005464_abnormal_platelet_physiology1.16474420
69MP0009278_abnormal_bone_marrow1.15562033
70MP0005394_taste/olfaction_phenotype1.15256431
71MP0005499_abnormal_olfactory_system1.15256431
72MP0002066_abnormal_motor_capabilities/c1.13343742
73MP0001963_abnormal_hearing_physiology1.13040944
74MP0006292_abnormal_olfactory_placode1.11421528
75MP0003121_genomic_imprinting1.11076557
76MP0005248_abnormal_Harderian_gland1.10862429
77MP0004883_abnormal_blood_vessel1.08434948
78MP0000955_abnormal_spinal_cord1.06803009
79MP0003631_nervous_system_phenotype1.03606500
80MP0002229_neurodegeneration1.03411883
81MP0001851_eye_inflammation1.03404249
82MP0000631_abnormal_neuroendocrine_gland1.02141066
83MP0005058_abnormal_lysosome_morphology1.00235639
84MP0002166_altered_tumor_susceptibility0.99449172
85MP0002638_abnormal_pupillary_reflex0.95182364
86MP0005174_abnormal_tail_pigmentation0.91422897
87MP0004885_abnormal_endolymph0.90873178
88MP0005387_immune_system_phenotype0.88852342
89MP0001790_abnormal_immune_system0.88852342
90MP0002152_abnormal_brain_morphology0.88109130
91MP0008789_abnormal_olfactory_epithelium0.86862856
92MP0005253_abnormal_eye_physiology0.86405430
93MP0003172_abnormal_lysosome_physiology0.85848074
94MP0003122_maternal_imprinting0.85027507
95MP0005535_abnormal_body_temperature0.84746023
96MP0004381_abnormal_hair_follicle0.84564366
97MP0008874_decreased_physiological_sensi0.83751072
98MP0000026_abnormal_inner_ear0.83478320
99MP0003646_muscle_fatigue0.82886000
100MP0004484_altered_response_of0.82571087
101MP0000920_abnormal_myelination0.82093256
102MP0001533_abnormal_skeleton_physiology0.81966303
103MP0000569_abnormal_digit_pigmentation0.80676257
104MP0000716_abnormal_immune_system0.80085006
105MP0002751_abnormal_autonomic_nervous0.79356619
106MP0003634_abnormal_glial_cell0.77247752
107MP0002069_abnormal_eating/drinking_beha0.76756201
108MP0009785_altered_susceptibility_to0.76362730
109MP0002090_abnormal_vision0.76017003
110MP0002752_abnormal_somatic_nervous0.75933168
111MP0001324_abnormal_eye_pigmentation0.75655840
112MP0000465_gastrointestinal_hemorrhage0.75070740
113MP0003303_peritoneal_inflammation0.74391401
114MP0002148_abnormal_hypersensitivity_rea0.73475485
115MP0003300_gastrointestinal_ulcer0.71867185
116MP0002398_abnormal_bone_marrow0.71574375
117MP0002133_abnormal_respiratory_system0.70534989
118MP0005388_respiratory_system_phenotype0.70534989
119MP0002928_abnormal_bile_duct0.70185498
120MP0002095_abnormal_skin_pigmentation0.70134125
121MP0002971_abnormal_brown_adipose0.69017262
122MP0008872_abnormal_physiological_respon0.68946223
123MP0002998_abnormal_bone_remodeling0.68885469
124MP0001177_atelectasis0.68116579
125MP0003075_altered_response_to0.67895675
126MP0000372_irregular_coat_pigmentation0.66549769
127MP0003329_amyloid_beta_deposits0.66101513
128MP0003632_abnormal_nervous_system0.64528166
129MP0005195_abnormal_posterior_eye0.63111499
130MP0001835_abnormal_antigen_presentation0.62999134
131MP0002419_abnormal_innate_immunity0.62669686
132MP0009697_abnormal_copulation0.62085511
133MP0005671_abnormal_response_to0.61254403
134MP0003724_increased_susceptibility_to0.60869259
135MP0008260_abnormal_autophagy0.59042323
136MP0000681_abnormal_thyroid_gland0.58798109
137MP0002909_abnormal_adrenal_gland0.57240880

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.96418951
2Hyperventilation (HP:0002883)6.00311762
3Febrile seizures (HP:0002373)5.67976721
4Epileptic encephalopathy (HP:0200134)5.54300732
5Atonic seizures (HP:0010819)4.94713699
6Focal seizures (HP:0007359)4.16130354
7Eczematoid dermatitis (HP:0000976)4.15922135
8Retrobulbar optic neuritis (HP:0100654)4.14135876
9Optic neuritis (HP:0100653)4.14135876
10Broad-based gait (HP:0002136)3.82325285
11Amyloidosis (HP:0011034)3.80772835
12Orchitis (HP:0100796)3.73998540
13Myositis (HP:0100614)3.73337767
14Abnormal hair whorl (HP:0010721)3.69610469
15Stomatitis (HP:0010280)3.68221978
16Abnormality of macrophages (HP:0004311)3.59327991
17Myokymia (HP:0002411)3.55556464
18Gait imbalance (HP:0002141)3.52683062
19Protruding tongue (HP:0010808)3.44660278
20Absence seizures (HP:0002121)3.39632200
21Hemiplegia (HP:0002301)3.37546226
22Progressive cerebellar ataxia (HP:0002073)3.35925813
23Medial flaring of the eyebrow (HP:0010747)3.34988043
24Dialeptic seizures (HP:0011146)3.27012286
25Drooling (HP:0002307)3.21620910
26Excessive salivation (HP:0003781)3.21620910
27Generalized tonic-clonic seizures (HP:0002069)3.20746467
28Hypothermia (HP:0002045)3.16496903
29Recurrent skin infections (HP:0001581)3.15073171
30Nephrogenic diabetes insipidus (HP:0009806)3.14593837
31Congenital primary aphakia (HP:0007707)3.12445505
32Blue irides (HP:0000635)3.00957991
33Fair hair (HP:0002286)2.98970967
34Gaze-evoked nystagmus (HP:0000640)2.93075425
35Keratoconjunctivitis sicca (HP:0001097)2.88253274
36Elevated erythrocyte sedimentation rate (HP:0003565)2.86542828
37Inability to walk (HP:0002540)2.86082288
38Chronic mucocutaneous candidiasis (HP:0002728)2.85891596
39Recurrent cutaneous fungal infections (HP:0011370)2.85891596
40Agitation (HP:0000713)2.81238513
41Difficulty running (HP:0009046)2.77273879
42Postural instability (HP:0002172)2.76739068
43Amyotrophic lateral sclerosis (HP:0007354)2.75822119
44Absent speech (HP:0001344)2.75183531
45Generalized hypopigmentation of hair (HP:0011358)2.73909947
46Gastrointestinal infarctions (HP:0005244)2.72269732
47Recurrent fungal infections (HP:0002841)2.70753677
48Keratoconjunctivitis (HP:0001096)2.67977936
49Progressive inability to walk (HP:0002505)2.65299939
50Fetal akinesia sequence (HP:0001989)2.62089389
51Episodic fever (HP:0001954)2.61494357
52Gingivitis (HP:0000230)2.60753743
53Ankle clonus (HP:0011448)2.59410966
54Thyroid-stimulating hormone excess (HP:0002925)2.58138559
55Disinhibition (HP:0000734)2.56536657
56Poor eye contact (HP:0000817)2.55304364
57Poor coordination (HP:0002370)2.54143290
58Truncal ataxia (HP:0002078)2.53900637
59Polyphagia (HP:0002591)2.50868410
60Visual hallucinations (HP:0002367)2.43831641
61Impaired vibration sensation in the lower limbs (HP:0002166)2.40869842
62Degeneration of the lateral corticospinal tracts (HP:0002314)2.40664434
63Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.40664434
64Abnormality of the corticospinal tract (HP:0002492)2.40301242
65Encephalitis (HP:0002383)2.38777333
66Abnormality of salivation (HP:0100755)2.38399894
67Neuronal loss in central nervous system (HP:0002529)2.36813133
68Genetic anticipation (HP:0003743)2.36174614
69Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.35469772
70Meningitis (HP:0001287)2.33594319
71Gingival bleeding (HP:0000225)2.33034205
72Pheochromocytoma (HP:0002666)2.32533282
73Abnormal eating behavior (HP:0100738)2.31226227
74Scanning speech (HP:0002168)2.30831757
75Arterial thrombosis (HP:0004420)2.29830972
76Vitreoretinal degeneration (HP:0000655)2.28945184
77Hemoptysis (HP:0002105)2.27991429
78Neuroendocrine neoplasm (HP:0100634)2.27050519
79Epileptiform EEG discharges (HP:0011182)2.25457121
80Diplopia (HP:0000651)2.23823200
81Abnormality of binocular vision (HP:0011514)2.23823200
82Papilledema (HP:0001085)2.23578617
83Papillary thyroid carcinoma (HP:0002895)2.23337497
84Recurrent abscess formation (HP:0002722)2.23245542
85Chest pain (HP:0100749)2.20287626
86Stereotypic behavior (HP:0000733)2.15763825
87Urticaria (HP:0001025)2.15679132
88Urinary bladder sphincter dysfunction (HP:0002839)2.15199103
89Specific learning disability (HP:0001328)2.13374675
90Failure to thrive in infancy (HP:0001531)2.13071358
91Pulmonary embolism (HP:0002204)2.11906472
92Dysdiadochokinesis (HP:0002075)2.11630156
93Prolonged bleeding time (HP:0003010)2.10820642
94Hypochromic microcytic anemia (HP:0004840)2.09812932
95Inappropriate behavior (HP:0000719)2.08189623
96Vaginal atresia (HP:0000148)2.07914710
97Supranuclear gaze palsy (HP:0000605)2.07859493
98Vertigo (HP:0002321)2.06834991
99Frequent falls (HP:0002359)2.06800013
100Sleep apnea (HP:0010535)2.05521296
101Increased cerebral lipofuscin (HP:0011813)2.05444064
102Memory impairment (HP:0002354)2.03716391
103Genital tract atresia (HP:0001827)2.03283553
104Amblyopia (HP:0000646)2.03121434
105Decreased central vision (HP:0007663)2.01290951
106Leukocytosis (HP:0001974)2.00268607
107Subaortic stenosis (HP:0001682)1.99718701
108Abnormality of the left ventricular outflow tract (HP:0011103)1.99718701
109Palpebral edema (HP:0100540)1.99323179
110Vasculitis (HP:0002633)1.98961037
111Lower limb muscle weakness (HP:0007340)1.98356708
112Abnormal social behavior (HP:0012433)1.97113162
113Impaired social interactions (HP:0000735)1.97113162
114True hermaphroditism (HP:0010459)1.96163639
115EEG with generalized epileptiform discharges (HP:0011198)1.95153234
116Recurrent bacterial skin infections (HP:0005406)1.94048482
117Neurofibrillary tangles (HP:0002185)1.91952271
118Spontaneous hematomas (HP:0007420)1.91584272
119Abnormality of the endocardium (HP:0004306)1.91057063
120Congenital stationary night blindness (HP:0007642)1.88950060
121Limb dystonia (HP:0002451)1.87827400
122Widely spaced teeth (HP:0000687)1.84716904
123Pulmonary infiltrates (HP:0002113)1.84609601
124Global brain atrophy (HP:0002283)1.84495658
125Truncal obesity (HP:0001956)1.84272358
126Impaired vibratory sensation (HP:0002495)1.83555276
127Gastroesophageal reflux (HP:0002020)1.82300749
128Akinesia (HP:0002304)1.82174551
129Hypsarrhythmia (HP:0002521)1.82110842
130Recurrent gram-negative bacterial infections (HP:0005420)1.82088862
131Thickened helices (HP:0000391)1.79517528
132Spastic gait (HP:0002064)1.79265618
133Mutism (HP:0002300)1.79105511
134Subacute progressive viral hepatitis (HP:0006572)1.77476202
135Action tremor (HP:0002345)1.76409639
136Ocular albinism (HP:0001107)1.76038033
137Obstructive sleep apnea (HP:0002870)1.76002997
138Generalized myoclonic seizures (HP:0002123)1.74964116
139Apathy (HP:0000741)1.74786240
140Dysmetria (HP:0001310)1.74402077
141Aplasia/Hypoplasia of the lens (HP:0008063)1.74125585
142Anxiety (HP:0000739)1.73948227
143Heterochromia iridis (HP:0001100)1.73055419
144Slow saccadic eye movements (HP:0000514)1.72074824
145Diminished motivation (HP:0000745)1.72025791
146Exotropia (HP:0000577)1.71833506
147Depression (HP:0000716)1.68481105
148Intellectual disability, severe (HP:0010864)1.68043964
149Clumsiness (HP:0002312)1.66028903
150Alveolar cell carcinoma (HP:0006519)1.65527457
151Hip dysplasia (HP:0001385)1.65466418
152Submucous cleft hard palate (HP:0000176)1.65383931
153Mediastinal lymphadenopathy (HP:0100721)1.61268291
154Central scotoma (HP:0000603)1.59782023
155Absent eyebrow (HP:0002223)1.59149382
156Obstructive lung disease (HP:0006536)1.58917939
157Chronic obstructive pulmonary disease (HP:0006510)1.58917939
158Urinary urgency (HP:0000012)1.58264251
159Abnormal rod and cone electroretinograms (HP:0008323)1.56054686

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK7.15558129
2PRPF4B3.10992485
3MAP2K72.99153326
4TNIK2.88030208
5MARK12.85000458
6AKT32.54735286
7MAP3K122.41534263
8NTRK32.40111194
9SGK22.31964726
10PLK22.31403178
11SIK32.20612980
12ERBB32.20116527
13EPHA42.19860253
14MAP3K42.07817130
15YES12.02950989
16SGK4941.85018144
17SGK2231.85018144
18CCNB11.77897849
19MAP2K31.75104174
20MAPK131.74939247
21DAPK21.73874233
22BMPR21.70038778
23MINK11.68723208
24RIPK41.67106771
25CDK191.64702399
26CSK1.64391996
27SGK31.64367523
28NTRK21.48524501
29KSR21.45696293
30DAPK11.34932946
31TYK21.32780643
32CAMK1G1.32341870
33ADRBK21.30343880
34GRK71.29776457
35BMPR1B1.23805334
36MAP2K41.23323232
37MAP3K141.21841848
38JAK21.21336707
39PNCK1.19083243
40MAP3K131.12837566
41WNK11.09586946
42TAOK31.08267413
43OXSR11.07906243
44ZAP701.06511538
45GRK61.06367779
46CAMK1D1.04697682
47PINK11.04566546
48HCK1.02808258
49BRD41.01626881
50MARK21.00283429
51PDK10.99073716
52ERBB20.97544573
53TXK0.97289806
54MAP3K90.96645530
55BTK0.93413992
56IRAK10.92452355
57PRKCG0.91622802
58CDK50.90302730
59CSF1R0.89751115
60FES0.85373693
61MUSK0.85276398
62KIT0.84360900
63JAK10.83727971
64TNK20.83121798
65TYRO30.82923106
66MKNK20.82781228
67MAP3K20.82627970
68GRK50.81705971
69CAMKK20.79337959
70PDPK10.77482875
71TEC0.76975321
72IRAK40.76873206
73PRKCE0.76285536
74LYN0.75545572
75MAP3K10.74476056
76CAMK2A0.74296481
77RET0.72700594
78SGK10.71700989
79DYRK20.71141949
80KSR10.69098428
81BCR0.68844765
82BRAF0.67814696
83MAPK120.66277272
84DYRK1A0.64507679
85IKBKE0.64147238
86TAOK10.63609135
87MAP4K10.63601016
88RPS6KA20.63408281
89CAMK2B0.62712897
90RAF10.59942292
91MAP3K70.59792727
92STK160.59724573
93MAPK70.58988485
94EIF2AK20.58621846
95ADRBK10.58415429
96FGFR30.58212901
97MOS0.56014172
98NEK60.55763110
99PAK30.55606621
100UHMK10.55247612
101PHKG20.54808938
102PHKG10.54808938
103LCK0.54249395
104INSRR0.53947341
105CAMKK10.53843187
106PKN10.53679161
107TSSK60.53578406
108CDK80.52193407
109PIK3CG0.51010884
110CAMK40.50424082
111EPHA30.50376184
112ITK0.48655855
113RPS6KB10.48345038
114FRK0.47707646
115PRKCH0.47270140
116MAPK100.47106760
117CDK180.46896424
118WNK30.46520058
119PDK20.45955594
120CDK60.44747195
121SIK20.44613101
122SYK0.44159305
123PDGFRB0.41720243
124PRKG10.41296917
125CDK30.41170387
126CLK10.39949666
127CAMK10.39183463
128CSNK1G20.38025543
129BLK0.37133769
130MAP3K60.37068414
131FGR0.37036782
132MAPK40.36098362
133CDK150.34087442
134IRAK20.34043951
135PRKCZ0.33775683
136ARAF0.31544320
137CDK140.30433498
138PAK60.29673171
139MYLK0.28924219
140PLK30.28007143
141FYN0.26502764
142PRKCB0.25428640
143PRKACA0.24996508
144STK110.24106689
145CDK11A0.24010398
146PTK2B0.23834198
147CAMK2D0.23688825

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.28427693
2Synaptic vesicle cycle_Homo sapiens_hsa047213.49164721
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.92517888
4Morphine addiction_Homo sapiens_hsa050322.83343996
5Olfactory transduction_Homo sapiens_hsa047402.78068075
6Phototransduction_Homo sapiens_hsa047442.74958832
7GABAergic synapse_Homo sapiens_hsa047272.68841719
8Circadian entrainment_Homo sapiens_hsa047132.53296196
9Collecting duct acid secretion_Homo sapiens_hsa049662.41700447
10Glutamatergic synapse_Homo sapiens_hsa047242.39361022
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.13142718
12Long-term potentiation_Homo sapiens_hsa047202.10151372
13Dorso-ventral axis formation_Homo sapiens_hsa043201.95752997
14Serotonergic synapse_Homo sapiens_hsa047261.94106812
15Dopaminergic synapse_Homo sapiens_hsa047281.89540343
16Amphetamine addiction_Homo sapiens_hsa050311.81653249
17B cell receptor signaling pathway_Homo sapiens_hsa046621.80869324
18Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.78212901
19Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.78209031
20Taste transduction_Homo sapiens_hsa047421.68983820
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.66270503
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.64655482
23Cholinergic synapse_Homo sapiens_hsa047251.56706671
24Rheumatoid arthritis_Homo sapiens_hsa053231.54763947
25Salivary secretion_Homo sapiens_hsa049701.54257750
26Long-term depression_Homo sapiens_hsa047301.52805871
27Vibrio cholerae infection_Homo sapiens_hsa051101.44705146
28Renin secretion_Homo sapiens_hsa049241.42111786
29Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.41291965
30Non-small cell lung cancer_Homo sapiens_hsa052231.38171438
31Type I diabetes mellitus_Homo sapiens_hsa049401.37542108
32Insulin secretion_Homo sapiens_hsa049111.35292795
33Calcium signaling pathway_Homo sapiens_hsa040201.31451875
34Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.28863096
35Phagosome_Homo sapiens_hsa041451.27042473
36Cocaine addiction_Homo sapiens_hsa050301.24523326
37SNARE interactions in vesicular transport_Homo sapiens_hsa041301.24365252
38Renal cell carcinoma_Homo sapiens_hsa052111.22748131
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.22435487
40Gastric acid secretion_Homo sapiens_hsa049711.17959416
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.13860256
42Platelet activation_Homo sapiens_hsa046111.08893843
43Phospholipase D signaling pathway_Homo sapiens_hsa040721.08366049
44Axon guidance_Homo sapiens_hsa043601.08056587
45Aldosterone synthesis and secretion_Homo sapiens_hsa049251.07296323
46Choline metabolism in cancer_Homo sapiens_hsa052311.04252764
47Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.04197145
48Acute myeloid leukemia_Homo sapiens_hsa052211.03976748
49Prolactin signaling pathway_Homo sapiens_hsa049171.03584618
50VEGF signaling pathway_Homo sapiens_hsa043701.03429872
51Oxytocin signaling pathway_Homo sapiens_hsa049210.99798988
52cAMP signaling pathway_Homo sapiens_hsa040240.98510947
53ErbB signaling pathway_Homo sapiens_hsa040120.98165581
54Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.91147310
55Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.88845489
56FoxO signaling pathway_Homo sapiens_hsa040680.87603345
57Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.87082496
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.87009391
59Chemokine signaling pathway_Homo sapiens_hsa040620.86531367
60African trypanosomiasis_Homo sapiens_hsa051430.85539661
61mTOR signaling pathway_Homo sapiens_hsa041500.84435032
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.83942804
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83839960
64Tuberculosis_Homo sapiens_hsa051520.82548448
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.78234109
66Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.77599908
67Graft-versus-host disease_Homo sapiens_hsa053320.77215225
68Chronic myeloid leukemia_Homo sapiens_hsa052200.74129376
69Pancreatic cancer_Homo sapiens_hsa052120.73602068
70Gap junction_Homo sapiens_hsa045400.72560023
71Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72485092
72Toxoplasmosis_Homo sapiens_hsa051450.72339955
73Malaria_Homo sapiens_hsa051440.71597372
74Adipocytokine signaling pathway_Homo sapiens_hsa049200.71280102
75Jak-STAT signaling pathway_Homo sapiens_hsa046300.70364903
76Thyroid hormone signaling pathway_Homo sapiens_hsa049190.69849740
77GnRH signaling pathway_Homo sapiens_hsa049120.69765795
78Type II diabetes mellitus_Homo sapiens_hsa049300.69716756
79Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.67860085
80Rap1 signaling pathway_Homo sapiens_hsa040150.67130308
81Hepatitis B_Homo sapiens_hsa051610.65997738
82Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65397452
83Allograft rejection_Homo sapiens_hsa053300.65060610
84Pertussis_Homo sapiens_hsa051330.64299977
85MAPK signaling pathway_Homo sapiens_hsa040100.64003337
86Melanogenesis_Homo sapiens_hsa049160.59565878
87Ether lipid metabolism_Homo sapiens_hsa005650.57157039
88Salmonella infection_Homo sapiens_hsa051320.56988289
89AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.56551536
90cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55709786
91Insulin signaling pathway_Homo sapiens_hsa049100.55501094
92Glioma_Homo sapiens_hsa052140.55371166
93HIF-1 signaling pathway_Homo sapiens_hsa040660.55305199
94TNF signaling pathway_Homo sapiens_hsa046680.54986108
95Leukocyte transendothelial migration_Homo sapiens_hsa046700.54816296
96Leishmaniasis_Homo sapiens_hsa051400.54407343
97Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.54212960
98Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54109196
99Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53383173
100Toll-like receptor signaling pathway_Homo sapiens_hsa046200.52127832
101Staphylococcus aureus infection_Homo sapiens_hsa051500.51986665
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.51724443
103Asthma_Homo sapiens_hsa053100.51006246
104Circadian rhythm_Homo sapiens_hsa047100.50960525
105Ras signaling pathway_Homo sapiens_hsa040140.50680279
106RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.49261764
107Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48786177
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48606000
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.48256196
110Regulation of autophagy_Homo sapiens_hsa041400.48085148
111Endometrial cancer_Homo sapiens_hsa052130.47512569
112Oxidative phosphorylation_Homo sapiens_hsa001900.46998838
113Intestinal immune network for IgA production_Homo sapiens_hsa046720.46818551
114Alzheimers disease_Homo sapiens_hsa050100.45630390
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44659502
116Autoimmune thyroid disease_Homo sapiens_hsa053200.43365006
117Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.42187852
118Osteoclast differentiation_Homo sapiens_hsa043800.39764367
119Vascular smooth muscle contraction_Homo sapiens_hsa042700.37069213
120Inositol phosphate metabolism_Homo sapiens_hsa005620.35372716
121Colorectal cancer_Homo sapiens_hsa052100.35322930
122Estrogen signaling pathway_Homo sapiens_hsa049150.34331891
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.34036756
124NOD-like receptor signaling pathway_Homo sapiens_hsa046210.32746282
125Alcoholism_Homo sapiens_hsa050340.30286705
126Legionellosis_Homo sapiens_hsa051340.28908055
127Ovarian steroidogenesis_Homo sapiens_hsa049130.26722345
128Influenza A_Homo sapiens_hsa051640.25880593
129T cell receptor signaling pathway_Homo sapiens_hsa046600.20516571
130Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.20465955
131Measles_Homo sapiens_hsa051620.19234880
132Hepatitis C_Homo sapiens_hsa051600.18341881

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