TMEM184B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1apoptotic cell clearance (GO:0043277)4.07773073
2regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.97642707
3regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.96423667
4hemidesmosome assembly (GO:0031581)3.74376414
5synaptic vesicle docking involved in exocytosis (GO:0016081)3.71787047
6planar cell polarity pathway involved in neural tube closure (GO:0090179)3.67066499
7Golgi transport vesicle coating (GO:0048200)3.66289563
8COPI coating of Golgi vesicle (GO:0048205)3.66289563
9plasma membrane repair (GO:0001778)3.60521713
10cell adhesion mediated by integrin (GO:0033627)3.56922571
11low-density lipoprotein particle clearance (GO:0034383)3.47694522
12stress fiber assembly (GO:0043149)3.44049199
13vascular endothelial growth factor signaling pathway (GO:0038084)3.41782723
14regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.33060216
15negative regulation of fatty acid transport (GO:2000192)3.24555291
16sodium ion export (GO:0071436)3.17728270
17endodermal cell differentiation (GO:0035987)3.16519103
18gonadal mesoderm development (GO:0007506)3.13503631
19basement membrane organization (GO:0071711)3.10219999
20positive regulation of receptor recycling (GO:0001921)3.06105567
21cytoskeletal anchoring at plasma membrane (GO:0007016)2.96140809
22cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.93092113
23protein heterotrimerization (GO:0070208)2.92309420
24maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.92095316
25desmosome organization (GO:0002934)2.90275396
26activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.85770339
27regulation of cholesterol storage (GO:0010885)2.85088864
28protein retention in ER lumen (GO:0006621)2.82899113
29regulation of early endosome to late endosome transport (GO:2000641)2.82794585
30glutamate secretion (GO:0014047)2.82091786
31regulation of extracellular matrix disassembly (GO:0010715)2.80935107
32protein localization to endosome (GO:0036010)2.80547786
33cell migration involved in sprouting angiogenesis (GO:0002042)2.77440368
34neuron projection extension involved in neuron projection guidance (GO:1902284)2.77333793
35axon extension involved in axon guidance (GO:0048846)2.77333793
36activation of Rac GTPase activity (GO:0032863)2.74202415
37peptidyl-proline hydroxylation (GO:0019511)2.72345478
38cell-cell junction maintenance (GO:0045217)2.68902959
39antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.68010720
40antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.68010720
41adherens junction assembly (GO:0034333)2.66981254
42positive regulation of nuclease activity (GO:0032075)2.66183600
43positive regulation of p38MAPK cascade (GO:1900745)2.63418355
44positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.62411403
45substrate-dependent cell migration (GO:0006929)2.61942887
46layer formation in cerebral cortex (GO:0021819)2.60471173
47positive regulation of histone deacetylation (GO:0031065)2.60090381
48blood vessel endothelial cell migration (GO:0043534)2.59048165
49collagen fibril organization (GO:0030199)2.57756771
50regulation of tight junction assembly (GO:2000810)2.57063071
51dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.57002579
52epithelial cell-cell adhesion (GO:0090136)2.56864217
53positive regulation of glycogen biosynthetic process (GO:0045725)2.55118545
54apoptotic process involved in morphogenesis (GO:0060561)2.54326969
55Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.53741858
56endocytic recycling (GO:0032456)2.53666739
57negative regulation of cell size (GO:0045792)2.51929257
58skin morphogenesis (GO:0043589)2.51600595
59atrioventricular valve morphogenesis (GO:0003181)2.51413379
60regulation of ARF protein signal transduction (GO:0032012)2.50167289
61actin filament depolymerization (GO:0030042)2.49471726
62retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.48863693
63regulation of fatty acid beta-oxidation (GO:0031998)2.47441933
64regulation of membrane protein ectodomain proteolysis (GO:0051043)2.46686558
65cell-substrate junction assembly (GO:0007044)2.45761378
66cell volume homeostasis (GO:0006884)2.45675961
67protein hydroxylation (GO:0018126)2.45507317
68positive regulation of endothelial cell apoptotic process (GO:2000353)2.45124552
69negative regulation of chondrocyte differentiation (GO:0032331)2.44017203
70endoplasmic reticulum unfolded protein response (GO:0030968)2.43203632
71protein maturation by protein folding (GO:0022417)2.42651619
72renal filtration (GO:0097205)2.42017491
73positive regulation of fatty acid beta-oxidation (GO:0032000)2.40400285
74negative regulation of catenin import into nucleus (GO:0035414)2.39731745
75actin filament bundle organization (GO:0061572)2.39330027
76actin filament bundle assembly (GO:0051017)2.39330027
77growth hormone receptor signaling pathway (GO:0060396)2.39204854
78regulation of p38MAPK cascade (GO:1900744)2.39187336
79insulin-like growth factor receptor signaling pathway (GO:0048009)2.39184797
80protein targeting to plasma membrane (GO:0072661)2.39179858
81regulation of establishment of planar polarity (GO:0090175)2.37969540
82substrate adhesion-dependent cell spreading (GO:0034446)2.37929075
83semaphorin-plexin signaling pathway (GO:0071526)2.37900932
84cellular potassium ion homeostasis (GO:0030007)2.37629639
85regulation of mammary gland epithelial cell proliferation (GO:0033599)2.36993801
86regulation of nuclease activity (GO:0032069)2.36851833
87vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.36631375
88regulation of cholesterol homeostasis (GO:2000188)2.36578612
89extracellular matrix assembly (GO:0085029)2.36436518
90response to fluid shear stress (GO:0034405)2.35578406
91response to laminar fluid shear stress (GO:0034616)2.34171206
92cellular response to interferon-alpha (GO:0035457)2.32876330
93positive regulation of protein dephosphorylation (GO:0035307)2.32814009
94G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.32719871
95endothelial cell morphogenesis (GO:0001886)2.31657496
96regulation of macrophage cytokine production (GO:0010935)2.31254248
97regulation of integrin activation (GO:0033623)2.31209894
98cellular response to unfolded protein (GO:0034620)2.30832789
99adherens junction organization (GO:0034332)2.29128333
100negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.28927569
101wound healing, spreading of epidermal cells (GO:0035313)2.28893063
102negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.28415394
103modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.27892409
104positive regulation by organism of defense response of other organism involved in symbiotic interact2.27892409
105modulation by symbiont of host immune response (GO:0052553)2.27892409
106positive regulation by symbiont of host defense response (GO:0052509)2.27892409
107modulation by symbiont of host defense response (GO:0052031)2.27892409
108modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.27892409
109positive regulation of synapse maturation (GO:0090129)2.27036471
110endothelial tube morphogenesis (GO:0061154)2.26353139
111morphogenesis of an endothelium (GO:0003159)2.26353139
112positive regulation of blood vessel endothelial cell migration (GO:0043536)2.25889870
113extracellular fibril organization (GO:0043206)2.25747133
114chondrocyte proliferation (GO:0035988)2.25708340
115cell migration involved in heart development (GO:0060973)2.25454505
116cerebellar granule cell differentiation (GO:0021707)2.25029793
117vesicle coating (GO:0006901)2.24677185
118endothelial cell chemotaxis (GO:0035767)2.24029727
119ER-nucleus signaling pathway (GO:0006984)2.23877716
120positive regulation of macrophage cytokine production (GO:0060907)2.23475981
121type B pancreatic cell proliferation (GO:0044342)2.23004490
122axon extension (GO:0048675)2.22794860
123antigen processing and presentation of endogenous antigen (GO:0019883)2.22791111
124retina vasculature morphogenesis in camera-type eye (GO:0061299)2.22722437
125cellular response to vitamin (GO:0071295)2.21617407
126bone trabecula formation (GO:0060346)2.21352385
127mating behavior (GO:0007617)2.21141360
128collagen metabolic process (GO:0032963)2.20885926
129cell-substrate adherens junction assembly (GO:0007045)2.19282305
130focal adhesion assembly (GO:0048041)2.19282305
131endothelial cell migration (GO:0043542)2.18763170
132endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.18658243
133barbed-end actin filament capping (GO:0051016)2.18541529
134positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.18393106
135establishment of endothelial barrier (GO:0061028)2.17851495
136negative regulation of heart growth (GO:0061117)2.17669498
137negative regulation of cardiac muscle tissue growth (GO:0055022)2.17669498
138cortical actin cytoskeleton organization (GO:0030866)2.17122079
139cortical cytoskeleton organization (GO:0030865)2.16663547
140embryo implantation (GO:0007566)2.16497735
141keratan sulfate catabolic process (GO:0042340)2.15786917
142positive regulation of axon extension (GO:0045773)2.15631805
143negative regulation of smooth muscle cell migration (GO:0014912)2.14647183
144cell communication by electrical coupling (GO:0010644)2.14217608
145L-serine transport (GO:0015825)2.14186142
146maternal placenta development (GO:0001893)2.13941549
147neuron projection extension (GO:1990138)2.13698558
148JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.13147546
149cellular response to topologically incorrect protein (GO:0035967)2.12558776
150positive regulation of fatty acid oxidation (GO:0046321)2.12298742
151L-alpha-amino acid transmembrane transport (GO:1902475)2.12290626
152platelet degranulation (GO:0002576)2.11740778
153multicellular organismal macromolecule metabolic process (GO:0044259)2.11731527
154collagen catabolic process (GO:0030574)2.11301139
155heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.09361817
156extracellular matrix disassembly (GO:0022617)2.09014549

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.41168587
2RARG_19884340_ChIP-ChIP_MEFs_Mouse3.31626184
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.00142727
4TP63_17297297_ChIP-ChIP_HaCaT_Human2.92029065
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.83213769
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.62972302
7CLOCK_20551151_ChIP-Seq_293T_Human2.56654015
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.53173663
9TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.23810879
10KDM2B_26808549_Chip-Seq_SUP-B15_Human2.23750476
11THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.22184635
12ELK3_25401928_ChIP-Seq_HUVEC_Human2.20369498
13LXR_22292898_ChIP-Seq_THP-1_Human2.07068665
14ESR2_21235772_ChIP-Seq_MCF-7_Human1.98834062
15RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.97831185
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.89645462
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.89402327
18KDM2B_26808549_Chip-Seq_DND41_Human1.88244469
19TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.77026220
20ERG_21242973_ChIP-ChIP_JURKAT_Human1.75403011
21ZFP281_18757296_ChIP-ChIP_E14_Mouse1.72978530
22KDM2B_26808549_Chip-Seq_K562_Human1.69670253
23RACK7_27058665_Chip-Seq_MCF-7_Human1.69054144
24WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.67466807
25RXR_22158963_ChIP-Seq_LIVER_Mouse1.66686620
26RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.65786304
27TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64688973
28KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.62410741
29PPARA_22158963_ChIP-Seq_LIVER_Mouse1.60501016
30P300_27058665_Chip-Seq_ZR-75-30cells_Human1.56778369
31STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.55831665
32NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.54740912
33ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.53335183
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.50407942
35* LXR_22158963_ChIP-Seq_LIVER_Mouse1.49990790
36* TCF7_22412390_ChIP-Seq_EML_Mouse1.49770839
37IRF8_22096565_ChIP-ChIP_GC-B_Human1.48513914
38SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.48114711
39CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.47558365
40TBX20_22328084_ChIP-Seq_HEART_Mouse1.47172789
41TBX20_22080862_ChIP-Seq_HEART_Mouse1.47172789
42NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.45778849
43TET1_21490601_ChIP-Seq_MESCs_Mouse1.44607712
44HIF1A_21447827_ChIP-Seq_MCF-7_Human1.43406852
45GATA2_21666600_ChIP-Seq_HMVEC_Human1.43348513
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42735738
47EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.42642587
48ATF3_27146783_Chip-Seq_COLON_Human1.40613662
49* TET1_21451524_ChIP-Seq_MESCs_Mouse1.39395926
50ESR1_21235772_ChIP-Seq_MCF-7_Human1.38305218
51KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.36921917
52TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.35819592
53MYC_22102868_ChIP-Seq_BL_Human1.35603914
54SMC4_20622854_ChIP-Seq_HELA_Human1.34847806
55EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.34254631
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.32896815
57CTCF_27219007_Chip-Seq_ERYTHROID_Human1.32685990
58KDM2B_26808549_Chip-Seq_JURKAT_Human1.32643070
59DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.30617127
60SPI1_23127762_ChIP-Seq_K562_Human1.29777189
61SA1_27219007_Chip-Seq_ERYTHROID_Human1.29316997
62P68_20966046_ChIP-Seq_HELA_Human1.28616907
63IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28392838
64SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.27789140
65TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.27004996
66SRY_22984422_ChIP-ChIP_TESTIS_Rat1.24991524
67UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.24485413
68ZFP281_27345836_Chip-Seq_ESCs_Mouse1.24139098
69SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.23680449
70EP300_21415370_ChIP-Seq_HL-1_Mouse1.22959084
71CTCF_27219007_Chip-Seq_Bcells_Human1.22905183
72SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.22727366
73* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.22575220
74NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.21078254
75NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.19846054
76PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.19675907
77FOXO3_23340844_ChIP-Seq_DLD1_Human1.19404794
78FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.19317048
79PPAR_26484153_Chip-Seq_NCI-H1993_Human1.18110864
80ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.17680935
81KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.17454261
82STAT6_21828071_ChIP-Seq_BEAS2B_Human1.16828180
83SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16657684
84EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16654031
85RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16654031
86POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.16239335
87E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.16030950
88VDR_21846776_ChIP-Seq_THP-1_Human1.15286224
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15109741
90SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.14868679
91CJUN_26792858_Chip-Seq_BT549_Human1.13138990
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.12983551
93NFIB_24661679_ChIP-Seq_LUNG_Mouse1.12272176
94IRF8_21731497_ChIP-ChIP_J774_Mouse1.11718080
95ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.11051050
96DROSHA_22980978_ChIP-Seq_HELA_Human1.10755791
97MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.08943683
98ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.08200742
99GATA1_19941826_ChIP-Seq_K562_Human1.07911038
100ZNF263_19887448_ChIP-Seq_K562_Human1.07861126
101BRD4_27068464_Chip-Seq_AML-cells_Mouse1.07165181
102* RARB_27405468_Chip-Seq_BRAIN_Mouse1.07006114
103JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06787342
104MAF_26560356_Chip-Seq_TH1_Human1.06419309
105IRF8_27001747_Chip-Seq_BMDM_Mouse1.06367243
106CREB1_26743006_Chip-Seq_LNCaP_Human1.06149040
107SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.05886895
108MTF2_20144788_ChIP-Seq_MESCs_Mouse1.04993640
109OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.04981441
110GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04386984
111CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.04180037
112CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.04063546
113SMC3_22415368_ChIP-Seq_MEFs_Mouse1.04039348
114TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.03097033
115TP53_22127205_ChIP-Seq_IMR90_Human1.02946940
116P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02623854
117ESR1_20079471_ChIP-ChIP_T-47D_Human1.01954219
118TP53_20018659_ChIP-ChIP_R1E_Mouse1.01076449
119ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00913550
120SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.00827431
121TP63_22573176_ChIP-Seq_HFKS_Human0.99702139
122JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99144601
123SMC1_22415368_ChIP-Seq_MEFs_Mouse0.98285956
124TP53_23651856_ChIP-Seq_MEFs_Mouse0.97581107
125Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.97253710
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.97141976
127SOX9_24532713_ChIP-Seq_HFSC_Mouse0.96802084
128RUNX1_27514584_Chip-Seq_MCF-7_Human0.96760774
129* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.95527224
130RNF2_27304074_Chip-Seq_ESCs_Mouse0.95392337
131UBF1/2_26484160_Chip-Seq_HMECs_Human0.95055015
132CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.94797546
133SUZ12_27294783_Chip-Seq_ESCs_Mouse0.94735189
134FOXA2_19822575_ChIP-Seq_HepG2_Human0.94600743
135MYB_21317192_ChIP-Seq_ERMYB_Mouse0.94392573
136* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.93192584

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.63647704
2MP0003705_abnormal_hypodermis_morpholog4.15944300
3MP0003279_aneurysm2.71084129
4MP0003566_abnormal_cell_adhesion2.57919097
5MP0005275_abnormal_skin_tensile2.53884627
6MP0003300_gastrointestinal_ulcer2.48727651
7MP0004272_abnormal_basement_membrane2.42236442
8MP0004859_abnormal_synaptic_plasticity2.41944777
9MP0010368_abnormal_lymphatic_system2.38576476
10MP0000013_abnormal_adipose_tissue2.23858690
11MP0002877_abnormal_melanocyte_morpholog2.13165479
12MP0003303_peritoneal_inflammation2.07148124
13MP0005623_abnormal_meninges_morphology2.05414924
14MP0010030_abnormal_orbit_morphology2.03402173
15MP0001958_emphysema2.03137817
16MP0005409_darkened_coat_color1.99358007
17MP0005058_abnormal_lysosome_morphology1.96369500
18MP0004510_myositis1.90830074
19MP0004858_abnormal_nervous_system1.89457352
20MP0005076_abnormal_cell_differentiation1.85349658
21MP0003091_abnormal_cell_migration1.85000859
22MP0003283_abnormal_digestive_organ1.83590808
23MP0002837_dystrophic_cardiac_calcinosis1.82477756
24MP0009840_abnormal_foam_cell1.81434619
25MP0005167_abnormal_blood-brain_barrier1.80884820
26MP0008260_abnormal_autophagy1.74990706
27MP0005503_abnormal_tendon_morphology1.73612235
28MP0010352_gastrointestinal_tract_polyps1.73368694
29MP0006054_spinal_hemorrhage1.72248048
30MP0005023_abnormal_wound_healing1.71963729
31MP0000678_abnormal_parathyroid_gland1.65557786
32MP0001879_abnormal_lymphatic_vessel1.62091332
33MP0000003_abnormal_adipose_tissue1.60820786
34MP0004084_abnormal_cardiac_muscle1.60662639
35MP0003045_fibrosis1.55228569
36MP0002249_abnormal_larynx_morphology1.45801586
37MP0009780_abnormal_chondrocyte_physiolo1.45180619
38MP0003172_abnormal_lysosome_physiology1.44030313
39MP0000733_abnormal_muscle_development1.43823047
40MP0000767_abnormal_smooth_muscle1.42888066
41MP0005670_abnormal_white_adipose1.41703160
42MP0005257_abnormal_intraocular_pressure1.40812378
43MP0002909_abnormal_adrenal_gland1.37399521
44MP0008961_abnormal_basal_metabolism1.35990492
45MP0004130_abnormal_muscle_cell1.32074426
46MP0003075_altered_response_to1.31892815
47MP0001533_abnormal_skeleton_physiology1.27598383
48MP0000343_altered_response_to1.27449789
49MP0009278_abnormal_bone_marrow1.27145815
50MP0005375_adipose_tissue_phenotype1.25626022
51MP0002295_abnormal_pulmonary_circulatio1.24531434
52MP0004087_abnormal_muscle_fiber1.23705898
53MP0003453_abnormal_keratinocyte_physiol1.23686187
54MP0002896_abnormal_bone_mineralization1.23123756
55MP0000751_myopathy1.21772583
56MP0009053_abnormal_anal_canal1.21045772
57MP0001542_abnormal_bone_strength1.18012813
58MP0004270_analgesia1.17901904
59MP0000579_abnormal_nail_morphology1.17064637
60MP0000762_abnormal_tongue_morphology1.16592444
61MP0005451_abnormal_body_composition1.15929901
62MP0000750_abnormal_muscle_regeneration1.15116848
63MP0002796_impaired_skin_barrier1.15114327
64MP0002998_abnormal_bone_remodeling1.13464286
65MP0003634_abnormal_glial_cell1.11566412
66MP0003828_pulmonary_edema1.11320676
67MP0010630_abnormal_cardiac_muscle1.11269556
68MP0003191_abnormal_cellular_cholesterol1.08296171
69MP0000537_abnormal_urethra_morphology1.07816439
70MP0000467_abnormal_esophagus_morphology1.07343975
71MP0002168_other_aberrant_phenotype1.06516969
72MP0004185_abnormal_adipocyte_glucose1.05144853
73MP0001849_ear_inflammation1.05129681
74MP0003436_decreased_susceptibility_to1.04512429
75MP0000566_synostosis1.03452274
76MP0005508_abnormal_skeleton_morphology1.01815289
77MP0003252_abnormal_bile_duct1.01418144
78MP0003942_abnormal_urinary_system1.01334973
79MP0006138_congestive_heart_failure1.00759672
80MP0008775_abnormal_heart_ventricle0.98154681
81MP0005330_cardiomyopathy0.97753787
82MP0009384_cardiac_valve_regurgitation0.97395228
83MP0000604_amyloidosis0.96570980
84MP0003448_altered_tumor_morphology0.96552851
85MP0005595_abnormal_vascular_smooth0.96509810
86MP0005385_cardiovascular_system_phenoty0.94580905
87MP0001544_abnormal_cardiovascular_syste0.94580905
88MP0001348_abnormal_lacrimal_gland0.93213725
89MP0002128_abnormal_blood_circulation0.92495358
90MP0005390_skeleton_phenotype0.92141393
91MP0005666_abnormal_adipose_tissue0.91704999
92MP0003879_abnormal_hair_cell0.91478519
93MP0003329_amyloid_beta_deposits0.91455341
94MP0000249_abnormal_blood_vessel0.90694831
95MP0000858_altered_metastatic_potential0.89812447
96MP0000749_muscle_degeneration0.89781148
97MP0002254_reproductive_system_inflammat0.88405326
98MP0002269_muscular_atrophy0.87130626
99MP0010234_abnormal_vibrissa_follicle0.86964397
100MP0000534_abnormal_ureter_morphology0.86754176
101MP0002933_joint_inflammation0.86399894
102MP0002108_abnormal_muscle_morphology0.86236964
103MP0006082_CNS_inflammation0.86189943
104MP0000462_abnormal_digestive_system0.85800150
105MP0002972_abnormal_cardiac_muscle0.85241547
106MP0004947_skin_inflammation0.85041627
107MP0005501_abnormal_skin_physiology0.84869369
108MP0002138_abnormal_hepatobiliary_system0.84219476
109MP0000759_abnormal_skeletal_muscle0.83607854
110MP0001614_abnormal_blood_vessel0.83159038
111MP0002925_abnormal_cardiovascular_devel0.82936298
112MP0003385_abnormal_body_wall0.81398070
113MP0003724_increased_susceptibility_to0.80709020
114MP0005083_abnormal_biliary_tract0.80588712
115MP0000920_abnormal_myelination0.79753740
116MP0004036_abnormal_muscle_relaxation0.79268070
117MP0003115_abnormal_respiratory_system0.79125050
118MP0005165_increased_susceptibility_to0.79007616
119MP0004233_abnormal_muscle_weight0.78559787
120MP0001915_intracranial_hemorrhage0.77685977
121MP0001243_abnormal_dermal_layer0.76710736
122MP0000681_abnormal_thyroid_gland0.76146412
123MP0005164_abnormal_response_to0.75591637
124MP0002060_abnormal_skin_morphology0.74204672
125MP0000266_abnormal_heart_morphology0.74077053
126MP0008569_lethality_at_weaning0.73822139
127MP0005621_abnormal_cell_physiology0.72766412
128MP0003183_abnormal_peptide_metabolism0.72243280
129MP0000747_muscle_weakness0.72218099
130MP0002932_abnormal_joint_morphology0.71889868
131MP0000428_abnormal_craniofacial_morphol0.70934781
132MP0002089_abnormal_postnatal_growth/wei0.69989891
133MP0001299_abnormal_eye_distance/0.69547096
134MP0003635_abnormal_synaptic_transmissio0.66043159
135MP0000163_abnormal_cartilage_morphology0.65753711
136MP0002116_abnormal_craniofacial_bone0.65147959
137MP0002113_abnormal_skeleton_development0.65033957

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.03989032
2Cerebral aneurysm (HP:0004944)4.50137343
3Premature rupture of membranes (HP:0001788)4.40736803
4Shallow orbits (HP:0000586)3.76446934
5Broad metatarsal (HP:0001783)3.28648001
6Peritonitis (HP:0002586)3.27801010
7Obstructive sleep apnea (HP:0002870)3.21976562
8Ankle contracture (HP:0006466)3.12988157
9Distal upper limb amyotrophy (HP:0007149)3.04238836
10Upper limb amyotrophy (HP:0009129)3.04238836
11Aortic dissection (HP:0002647)3.01558578
12Aortic aneurysm (HP:0004942)2.99776399
13Dilatation of the ascending aorta (HP:0005111)2.97820379
14Cervical subluxation (HP:0003308)2.81466937
15Aneurysm (HP:0002617)2.79725295
16Mitral valve prolapse (HP:0001634)2.79073316
17Bladder diverticulum (HP:0000015)2.72033860
18Increased connective tissue (HP:0009025)2.71867558
19Hand muscle atrophy (HP:0009130)2.71788346
20Dysostosis multiplex (HP:0000943)2.66889120
21Increased cerebral lipofuscin (HP:0011813)2.64976999
22Atrophic scars (HP:0001075)2.64369713
23Striae distensae (HP:0001065)2.63862939
24Mucopolysacchariduria (HP:0008155)2.55389329
25Urinary glycosaminoglycan excretion (HP:0003541)2.55389329
26Broad face (HP:0000283)2.51066771
27Distal lower limb amyotrophy (HP:0008944)2.49305818
28Long toe (HP:0010511)2.49278353
29Vascular tortuosity (HP:0004948)2.45304941
30Vertebral compression fractures (HP:0002953)2.44982490
31Abnormality of dentin (HP:0010299)2.43945426
32Mitral regurgitation (HP:0001653)2.43617187
33Genu recurvatum (HP:0002816)2.41719336
34Abnormality of mucopolysaccharide metabolism (HP:0011020)2.40501522
35Abnormality of polysaccharide metabolism (HP:0011012)2.40501522
36Abnormality of glycosaminoglycan metabolism (HP:0004371)2.40501522
37Neurofibrillary tangles (HP:0002185)2.38722240
38Supranuclear gaze palsy (HP:0000605)2.36112458
39Asymmetric septal hypertrophy (HP:0001670)2.34829845
40Lymphangioma (HP:0100764)2.33882905
41Arterial tortuosity (HP:0005116)2.29782377
42Fragile skin (HP:0001030)2.29461013
43Type 1 muscle fiber predominance (HP:0003803)2.28589998
44Distal lower limb muscle weakness (HP:0009053)2.28061458
45Blue sclerae (HP:0000592)2.27777125
46Hypercortisolism (HP:0001578)2.26742099
47Spinal rigidity (HP:0003306)2.25405490
48Cerebral inclusion bodies (HP:0100314)2.24517522
49Lower limb amyotrophy (HP:0007210)2.17760252
50Turricephaly (HP:0000262)2.15787849
51Stridor (HP:0010307)2.15252129
52Increased variability in muscle fiber diameter (HP:0003557)2.13199117
53Long palpebral fissure (HP:0000637)2.13053222
54Wrist flexion contracture (HP:0001239)2.12526067
55Neonatal short-limb short stature (HP:0008921)2.12088029
56Mildly elevated creatine phosphokinase (HP:0008180)2.11996833
57Insomnia (HP:0100785)2.10458124
58Disproportionate tall stature (HP:0001519)2.09224794
59Hypoventilation (HP:0002791)2.07986817
60Camptodactyly of toe (HP:0001836)2.07049730
61Hematochezia (HP:0002573)2.06324358
62Right ventricular cardiomyopathy (HP:0011663)2.05835517
63Mitral stenosis (HP:0001718)2.04537801
64Hyperextensible skin (HP:0000974)2.04229217
65Deep venous thrombosis (HP:0002625)2.02448181
66Soft skin (HP:0000977)2.01868194
67Polycythemia (HP:0001901)2.01007739
68Wormian bones (HP:0002645)2.00750891
69Slender build (HP:0001533)1.98867631
70Nuclear cataract (HP:0100018)1.96996799
71Bowel diverticulosis (HP:0005222)1.96892919
72Enlarged penis (HP:0000040)1.96841489
73Increased neuronal autofluorescent lipopigment (HP:0002074)1.95611971
74Difficulty climbing stairs (HP:0003551)1.94251985
75Natal tooth (HP:0000695)1.93712884
76Follicular hyperkeratosis (HP:0007502)1.91710192
77Muscle fiber splitting (HP:0003555)1.91491863
78Thin bony cortex (HP:0002753)1.91365131
79Abnormality of the distal phalanges of the toes (HP:0010182)1.90693205
80Ectopia lentis (HP:0001083)1.88849682
81Myocardial infarction (HP:0001658)1.88526150
82Hyporeflexia of lower limbs (HP:0002600)1.87930866
83Abnormality of skeletal muscle fiber size (HP:0012084)1.87698305
84Systemic lupus erythematosus (HP:0002725)1.87404802
85Achilles tendon contracture (HP:0001771)1.84008506
86Spondylolisthesis (HP:0003302)1.83663708
87Flat acetabular roof (HP:0003180)1.82877024
88Axonal loss (HP:0003447)1.81405507
89Centrally nucleated skeletal muscle fibers (HP:0003687)1.80847647
90Abnormality of liposaccharide metabolism (HP:0010968)1.80576558
91Abnormality of glycosphingolipid metabolism (HP:0004343)1.80576558
92Abnormality of glycolipid metabolism (HP:0010969)1.80576558
93Esophageal varix (HP:0002040)1.80186696
94Bronchomalacia (HP:0002780)1.77972741
95Osteopenia (HP:0000938)1.77744045
96Coxa vara (HP:0002812)1.77545750
97Difficulty running (HP:0009046)1.77245177
98Ulnar bowing (HP:0003031)1.77135557
99Arnold-Chiari malformation (HP:0002308)1.76589393
100Abnormality of the peritoneum (HP:0002585)1.76366512
101Advanced eruption of teeth (HP:0006288)1.75956621
102Hyperacusis (HP:0010780)1.75912289
103Scapular winging (HP:0003691)1.75470638
104Joint laxity (HP:0001388)1.73990847
105Round ear (HP:0100830)1.73439638
106Abnormality of the Achilles tendon (HP:0005109)1.73200997
107Nonimmune hydrops fetalis (HP:0001790)1.73187436
108Polygenic inheritance (HP:0010982)1.73050872
109Premature skin wrinkling (HP:0100678)1.72050929
110Abnormality of the distal phalanx of the thumb (HP:0009617)1.70871867
111Frequent falls (HP:0002359)1.70305807
112Mesangial abnormality (HP:0001966)1.69626668
113Short nail (HP:0001799)1.69256860
114Bowing of the arm (HP:0006488)1.68953486
115Bowed forearm bones (HP:0003956)1.68953486
116Renal duplication (HP:0000075)1.68569418
117Increased density of long bones (HP:0006392)1.68294769
118Osteolytic defects of the hand bones (HP:0009699)1.68214263
119Osteolytic defects of the phalanges of the hand (HP:0009771)1.68214263
120Abnormality of the acetabulum (HP:0003170)1.67810073
121Trismus (HP:0000211)1.66414728
122Macroorchidism (HP:0000053)1.66211486
123Skin nodule (HP:0200036)1.66024979
124Loss of speech (HP:0002371)1.65855551
125Joint stiffness (HP:0001387)1.65669019
126Interstitial pulmonary disease (HP:0006530)1.65272881
127Spinal cord compression (HP:0002176)1.65010591
128Generalized amyotrophy (HP:0003700)1.64374453
129Overgrowth (HP:0001548)1.64050949
130Flexion contracture of toe (HP:0005830)1.63062673
131Joint contractures involving the joints of the feet (HP:0100492)1.63062673
132Sudden death (HP:0001699)1.62986783
133Biconcave vertebral bodies (HP:0004586)1.62709149
134Congenital glaucoma (HP:0001087)1.62521699
135Deviation of the hallux (HP:0010051)1.61838378
136Back pain (HP:0003418)1.61338238
137Hyperparathyroidism (HP:0000843)1.60813944
138J-shaped sella turcica (HP:0002680)1.59963093
139Hypoglycemic coma (HP:0001325)1.58676426
140Elbow flexion contracture (HP:0002987)1.57805470

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.81349057
2ERN13.87569607
3PKN23.09222250
4RIPK12.83066435
5PRPF4B2.61414088
6TTN2.54883298
7PDGFRA2.46767020
8SMG12.15749298
9SIK12.02222832
10PTK61.94043370
11NTRK11.93232290
12KDR1.88782578
13TGFBR21.80754879
14PRKD31.79820895
15IRAK31.75749872
16ARAF1.71992374
17PTK21.63349485
18DDR21.63273278
19EPHB11.59009563
20KSR21.56687258
21FGFR41.55404887
22MST1R1.52430531
23BMX1.44521637
24MAP3K101.42358535
25TIE11.39816529
26LIMK11.37860473
27CAMK1D1.31308819
28MARK21.29233014
29JAK11.29014728
30EPHB21.28714976
31TAOK21.27543814
32TBK11.26008679
33PAK41.25095101
34PRKCH1.22983415
35TAOK11.21421686
36LATS21.20757959
37LRRK21.18004639
38EEF2K1.12871116
39DMPK1.10336484
40RET1.06010063
41TYK21.05459294
42EPHA31.04770588
43CAMKK11.03735639
44CAMK1G1.03102858
45MAP3K91.01915955
46JAK30.99200932
47FER0.97726947
48MAP3K20.97692405
49MAP3K10.96265788
50PAK60.95604993
51PAK30.91481650
52MYLK0.90058646
53MAP3K60.90032841
54LMTK20.89795438
55SCYL20.89695312
56MTOR0.89149610
57PAK20.88386256
58FLT30.87107857
59PTK2B0.84673259
60MAPKAPK30.84306150
61MET0.83241069
62TESK10.82464246
63LATS10.82226278
64MAP3K130.81816373
65ALK0.80804022
66PDGFRB0.79934988
67EPHA20.79804146
68MAP2K10.77139497
69CSK0.76960722
70ICK0.76794787
71BRAF0.75529649
72FGFR30.74258091
73ROCK20.73242923
74PRKD10.73110135
75CDK120.71752701
76DAPK30.70913161
77DAPK20.70330571
78TESK20.69087604
79PRKG20.68968981
80MOS0.66933593
81EPHA40.66636358
82MAPK150.64749789
83JAK20.63170535
84MAP2K30.62754336
85ILK0.61092846
86MAP3K30.60206335
87ZAP700.59349309
88STK380.59196480
89RPS6KC10.57032930
90RPS6KL10.57032930
91NEK90.56638914
92PRKD20.56567959
93CHUK0.53792683
94FGFR10.53346484
95RPS6KA40.52544700
96CDC42BPA0.52122815
97SIK30.50304878
98EGFR0.49362591
99NTRK30.49359138
100ROCK10.48216686
101PIM20.47526649
102MAP3K70.47462384
103HIPK20.47267280
104SRC0.47013714
105KIT0.46935163
106HCK0.46855790
107SGK30.46432065
108CAMK2G0.46333243
109DYRK1B0.46185550
110MAP3K110.45603205
111TYRO30.45464238
112SIK20.45104690
113MARK10.45101031
114UHMK10.44522040
115PDPK10.44431062
116CDK150.44394089
117NME20.44371612
118CAMKK20.43366825
119MAP3K80.43010820
120RPS6KA20.42801229
121CAMK2B0.42526812
122CDK11A0.42255074
123IRAK20.41865677
124ABL20.41040476
125INSRR0.40971576
126TRPM70.40655684
127MAPK70.40222286
128CDK180.39755703
129ERBB40.39589267
130IKBKE0.38227324
131PAK10.37734161
132CDK60.37521270
133INSR0.37380019
134CAMK10.36425924
135MATK0.35431271
136RPS6KA60.34926199

Predicted pathways (KEGG)

RankGene SetZ-score
1Focal adhesion_Homo sapiens_hsa045101.74963844
2Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.74205337
3Nitrogen metabolism_Homo sapiens_hsa009101.66957286
4ECM-receptor interaction_Homo sapiens_hsa045121.58762626
5Lysosome_Homo sapiens_hsa041421.57552615
6Glycosaminoglycan degradation_Homo sapiens_hsa005311.57306030
7Dilated cardiomyopathy_Homo sapiens_hsa054141.53705875
8Amoebiasis_Homo sapiens_hsa051461.53385860
9Synaptic vesicle cycle_Homo sapiens_hsa047211.49730342
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.47539751
11Vibrio cholerae infection_Homo sapiens_hsa051101.45543884
12Chronic myeloid leukemia_Homo sapiens_hsa052201.44256191
13Proteoglycans in cancer_Homo sapiens_hsa052051.41041263
14Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.38700757
15Type II diabetes mellitus_Homo sapiens_hsa049301.35581717
16Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.30868329
17Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.28447975
18Bladder cancer_Homo sapiens_hsa052191.27819965
19Adherens junction_Homo sapiens_hsa045201.26866970
20Staphylococcus aureus infection_Homo sapiens_hsa051501.22109344
21Long-term potentiation_Homo sapiens_hsa047201.22048054
22Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.21725388
23Insulin resistance_Homo sapiens_hsa049311.21172762
24Axon guidance_Homo sapiens_hsa043601.20238827
25Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.18467228
26Leishmaniasis_Homo sapiens_hsa051401.16797537
27Leukocyte transendothelial migration_Homo sapiens_hsa046701.14854118
28Melanogenesis_Homo sapiens_hsa049161.14054847
29Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.14029863
30Toxoplasmosis_Homo sapiens_hsa051451.13003227
31ErbB signaling pathway_Homo sapiens_hsa040121.12929041
32Adipocytokine signaling pathway_Homo sapiens_hsa049201.12445988
33Osteoclast differentiation_Homo sapiens_hsa043801.12230278
34Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.11576939
35Malaria_Homo sapiens_hsa051441.10765267
36TNF signaling pathway_Homo sapiens_hsa046681.09095216
37Neurotrophin signaling pathway_Homo sapiens_hsa047221.07279662
38Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05526439
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.04843750
40Glioma_Homo sapiens_hsa052141.04137658
41Viral myocarditis_Homo sapiens_hsa054161.04083483
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.03993370
43Thyroid cancer_Homo sapiens_hsa052160.99716266
44Gap junction_Homo sapiens_hsa045400.97733977
45VEGF signaling pathway_Homo sapiens_hsa043700.97635482
46Small cell lung cancer_Homo sapiens_hsa052220.97350826
47Pancreatic cancer_Homo sapiens_hsa052120.96961329
48Prion diseases_Homo sapiens_hsa050200.95510801
49Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.93977746
50Shigellosis_Homo sapiens_hsa051310.93626439
51Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93612111
52Estrogen signaling pathway_Homo sapiens_hsa049150.93137179
53Toll-like receptor signaling pathway_Homo sapiens_hsa046200.92805304
54Arginine biosynthesis_Homo sapiens_hsa002200.92654166
55mTOR signaling pathway_Homo sapiens_hsa041500.91393397
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.89819232
57Renal cell carcinoma_Homo sapiens_hsa052110.87969655
58Pertussis_Homo sapiens_hsa051330.87745452
59Cocaine addiction_Homo sapiens_hsa050300.86897648
60Tight junction_Homo sapiens_hsa045300.86571157
61Gastric acid secretion_Homo sapiens_hsa049710.86243186
62Other glycan degradation_Homo sapiens_hsa005110.86041172
63Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85925890
64Galactose metabolism_Homo sapiens_hsa000520.85345720
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.84985879
66Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84653218
67Insulin signaling pathway_Homo sapiens_hsa049100.84286337
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84101367
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.83439637
70Prolactin signaling pathway_Homo sapiens_hsa049170.82427634
71Inositol phosphate metabolism_Homo sapiens_hsa005620.81980931
72Dorso-ventral axis formation_Homo sapiens_hsa043200.81854641
73Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80578669
74Rap1 signaling pathway_Homo sapiens_hsa040150.80446073
75Salmonella infection_Homo sapiens_hsa051320.80063463
76Platelet activation_Homo sapiens_hsa046110.80055682
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79806919
78Pentose phosphate pathway_Homo sapiens_hsa000300.79471809
79Longevity regulating pathway - mammal_Homo sapiens_hsa042110.79125981
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.78939679
81Bile secretion_Homo sapiens_hsa049760.78426954
82Vitamin B6 metabolism_Homo sapiens_hsa007500.78422564
83Tuberculosis_Homo sapiens_hsa051520.78000807
84Complement and coagulation cascades_Homo sapiens_hsa046100.77829155
85Endocytosis_Homo sapiens_hsa041440.77746191
86Choline metabolism in cancer_Homo sapiens_hsa052310.77208185
87Notch signaling pathway_Homo sapiens_hsa043300.76478289
88PPAR signaling pathway_Homo sapiens_hsa033200.76022299
89Acute myeloid leukemia_Homo sapiens_hsa052210.75877593
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.75789370
91Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.75273974
92Fructose and mannose metabolism_Homo sapiens_hsa000510.73565954
93Insulin secretion_Homo sapiens_hsa049110.73104258
94Chemokine signaling pathway_Homo sapiens_hsa040620.72252688
952-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.71578578
96Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71044154
97Legionellosis_Homo sapiens_hsa051340.69724204
98Basal cell carcinoma_Homo sapiens_hsa052170.69655548
99Apoptosis_Homo sapiens_hsa042100.69292107
100Prostate cancer_Homo sapiens_hsa052150.68353509
101Protein digestion and absorption_Homo sapiens_hsa049740.68198339
102Pathways in cancer_Homo sapiens_hsa052000.68142274
103Endometrial cancer_Homo sapiens_hsa052130.68059093
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68029227
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.66597970
106HIF-1 signaling pathway_Homo sapiens_hsa040660.65932483
107MicroRNAs in cancer_Homo sapiens_hsa052060.65431865
108Aldosterone synthesis and secretion_Homo sapiens_hsa049250.65424141
109MAPK signaling pathway_Homo sapiens_hsa040100.64301334
110Cholinergic synapse_Homo sapiens_hsa047250.64191553
111Melanoma_Homo sapiens_hsa052180.63197609
112Fatty acid degradation_Homo sapiens_hsa000710.62253417
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62204239
114Dopaminergic synapse_Homo sapiens_hsa047280.61963941
115N-Glycan biosynthesis_Homo sapiens_hsa005100.61847811
116Non-small cell lung cancer_Homo sapiens_hsa052230.60962264
117Wnt signaling pathway_Homo sapiens_hsa043100.60914819
118Oxytocin signaling pathway_Homo sapiens_hsa049210.60816294
119Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60746996
120Hepatitis B_Homo sapiens_hsa051610.60247868
121Ras signaling pathway_Homo sapiens_hsa040140.60043702
122Lysine degradation_Homo sapiens_hsa003100.59338725
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.58973132
124Hippo signaling pathway_Homo sapiens_hsa043900.58408236
125Amphetamine addiction_Homo sapiens_hsa050310.58031721
126B cell receptor signaling pathway_Homo sapiens_hsa046620.57949227
127Hedgehog signaling pathway_Homo sapiens_hsa043400.57689279
128cAMP signaling pathway_Homo sapiens_hsa040240.57655596
129Hepatitis C_Homo sapiens_hsa051600.57010736
130AMPK signaling pathway_Homo sapiens_hsa041520.56607223
131GnRH signaling pathway_Homo sapiens_hsa049120.55569072
132Fatty acid metabolism_Homo sapiens_hsa012120.53794212
133cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53235024
134Glucagon signaling pathway_Homo sapiens_hsa049220.52232816
135Thyroid hormone synthesis_Homo sapiens_hsa049180.52119502
136Colorectal cancer_Homo sapiens_hsa052100.49681485
137Phagosome_Homo sapiens_hsa041450.49289447

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