TMEM200A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vocalization behavior (GO:0071625)5.63247953
2neuron cell-cell adhesion (GO:0007158)5.35611416
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.04018687
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.79888809
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.76656057
6protein localization to synapse (GO:0035418)4.70969755
7neuron recognition (GO:0008038)4.63228511
8synaptic vesicle exocytosis (GO:0016079)4.58362686
9sequestering of extracellular ligand from receptor (GO:0035581)4.47370188
10regulation of glutamate receptor signaling pathway (GO:1900449)4.36638693
11ionotropic glutamate receptor signaling pathway (GO:0035235)4.35828396
12axonal fasciculation (GO:0007413)4.28855083
13protein heterotrimerization (GO:0070208)4.27099875
14glutamate secretion (GO:0014047)4.26560149
15chondrocyte proliferation (GO:0035988)4.17488168
16positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.13075696
17cell migration in hindbrain (GO:0021535)4.11384376
18locomotory exploration behavior (GO:0035641)4.11149508
19exploration behavior (GO:0035640)4.02846526
20layer formation in cerebral cortex (GO:0021819)4.00482618
21regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.98530462
22glutamate receptor signaling pathway (GO:0007215)3.97535875
23regulation of synaptic vesicle exocytosis (GO:2000300)3.97535001
24synaptic vesicle maturation (GO:0016188)3.95376154
25negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.92420247
26regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.91857753
27pyrimidine nucleobase catabolic process (GO:0006208)3.91400313
28positive regulation of synapse maturation (GO:0090129)3.89739703
29cell adhesion mediated by integrin (GO:0033627)3.86968935
30cellular response to vitamin D (GO:0071305)3.77141961
31regulation of type B pancreatic cell apoptotic process (GO:2000674)3.76729027
32wound healing, spreading of epidermal cells (GO:0035313)3.70807655
33presynaptic membrane assembly (GO:0097105)3.70720527
34synaptic transmission, glutamatergic (GO:0035249)3.65274480
35dendritic spine morphogenesis (GO:0060997)3.64317671
36substrate-dependent cell migration (GO:0006929)3.64210044
37proline transport (GO:0015824)3.62618119
38regulation of long-term neuronal synaptic plasticity (GO:0048169)3.62190941
39postsynaptic membrane organization (GO:0001941)3.60169384
40neuron-neuron synaptic transmission (GO:0007270)3.58655150
41neurotransmitter-gated ion channel clustering (GO:0072578)3.58571623
42innervation (GO:0060384)3.57796701
43regulation of neuronal synaptic plasticity (GO:0048168)3.53993251
44COPII vesicle coating (GO:0048208)3.51533297
45collagen fibril organization (GO:0030199)3.48651970
46mating behavior (GO:0007617)3.46578281
47regulation of synaptic vesicle transport (GO:1902803)3.44370999
48cellular response to vitamin (GO:0071295)3.44197419
49positive regulation of synapse assembly (GO:0051965)3.40117660
50regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.38784127
51neurotransmitter secretion (GO:0007269)3.38229286
52nucleobase catabolic process (GO:0046113)3.37740274
53startle response (GO:0001964)3.37068511
54negative regulation of synaptic transmission, GABAergic (GO:0032229)3.36285269
55dendrite morphogenesis (GO:0048813)3.35762931
56negative regulation of hormone biosynthetic process (GO:0032353)3.35525547
57skin morphogenesis (GO:0043589)3.34400634
58regulation of excitatory postsynaptic membrane potential (GO:0060079)3.34192841
59negative regulation of microtubule polymerization (GO:0031115)3.32782400
60central nervous system projection neuron axonogenesis (GO:0021952)3.32308583
61neuronal action potential propagation (GO:0019227)3.29960705
62behavioral defense response (GO:0002209)3.29428316
63behavioral fear response (GO:0001662)3.29428316
64smooth muscle tissue development (GO:0048745)3.26967606
65regulation of postsynaptic membrane potential (GO:0060078)3.26778566
66synaptic vesicle endocytosis (GO:0048488)3.26072401
67presynaptic membrane organization (GO:0097090)3.25534632
68regulation of synaptic transmission, glutamatergic (GO:0051966)3.25169271
69synapse assembly (GO:0007416)3.25050162
70endodermal cell differentiation (GO:0035987)3.24962457
71negative regulation of axon extension involved in axon guidance (GO:0048843)3.19228547
72synaptic vesicle docking involved in exocytosis (GO:0016081)3.17857920
73regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.16576590
74positive regulation of gastrulation (GO:2000543)3.15467456
75regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.15427334
76long-term synaptic potentiation (GO:0060291)3.12243554
77fear response (GO:0042596)3.11426461
78ganglion development (GO:0061548)3.10514606
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.10195850
80cell migration involved in sprouting angiogenesis (GO:0002042)3.09992861
81regulation of dendritic spine morphogenesis (GO:0061001)3.08122295
82transmission of nerve impulse (GO:0019226)3.07799313
83negative regulation of axon guidance (GO:1902668)3.07610090
84regulation of synapse assembly (GO:0051963)3.06911010
85regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.05174182
86regulation of synapse structural plasticity (GO:0051823)3.04330391
87regulation of synapse maturation (GO:0090128)3.03998858
88intraspecies interaction between organisms (GO:0051703)3.03786400
89social behavior (GO:0035176)3.03786400
90regulation of vesicle fusion (GO:0031338)2.99634283
91glucocorticoid biosynthetic process (GO:0006704)2.99022611
92synapse organization (GO:0050808)2.97892065
93positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.97553788
94regulation of synaptic plasticity (GO:0048167)2.96095663
95axon extension (GO:0048675)2.95345445
96positive regulation of synaptic transmission, GABAergic (GO:0032230)2.93432803
97regulation of respiratory system process (GO:0044065)2.93283564
98neuron projection extension involved in neuron projection guidance (GO:1902284)2.92906473
99axon extension involved in axon guidance (GO:0048846)2.92906473
100positive regulation of protein autophosphorylation (GO:0031954)2.90183391
101regulation of acrosome reaction (GO:0060046)2.88964931
102membrane depolarization (GO:0051899)2.88893235
103membrane depolarization during action potential (GO:0086010)2.88620779
104negative regulation of dendrite development (GO:2000171)2.86281048
105learning (GO:0007612)2.85184352
106regulation of synapse organization (GO:0050807)2.84169844
107cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.83083784
108regulation of dopamine secretion (GO:0014059)2.82763065
109positive regulation of hormone biosynthetic process (GO:0046886)2.81666516
110negative regulation of hormone metabolic process (GO:0032351)2.80138124
111regulation of neurotransmitter secretion (GO:0046928)2.80052945
112membrane hyperpolarization (GO:0060081)2.77371799
113cerebellar Purkinje cell differentiation (GO:0021702)2.77064173
114toxin metabolic process (GO:0009404)2.76031685
115neurotransmitter transport (GO:0006836)2.75979821
116response to hepatocyte growth factor (GO:0035728)2.74907651
117cellular response to hepatocyte growth factor stimulus (GO:0035729)2.74907651
118regulation of synaptic transmission, GABAergic (GO:0032228)2.74898211
119G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.74372858
120auditory behavior (GO:0031223)2.72794126
121hippocampus development (GO:0021766)2.72788627
122activation of protein kinase A activity (GO:0034199)2.72318231
123central nervous system neuron axonogenesis (GO:0021955)2.72253383
124multi-organism behavior (GO:0051705)2.71136055
125regulation of glutamate secretion (GO:0014048)2.70537592
126regulation of axon extension involved in axon guidance (GO:0048841)2.69905065
127positive regulation of membrane potential (GO:0045838)2.68938285
128response to auditory stimulus (GO:0010996)2.68840529
129long-term memory (GO:0007616)2.68222573
130response to histamine (GO:0034776)2.68187522
131cochlea development (GO:0090102)2.67959328
132establishment of nucleus localization (GO:0040023)2.67332114
133kidney mesenchyme development (GO:0072074)2.66343947
134membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.66177384
135adhesion of symbiont to host (GO:0044406)2.66147222
136response to follicle-stimulating hormone (GO:0032354)2.66134445
137type B pancreatic cell proliferation (GO:0044342)2.65086457
138retinal cone cell development (GO:0046549)2.63645535
139regulation of transforming growth factor beta2 production (GO:0032909)2.63141117
140regulation of hexokinase activity (GO:1903299)2.62690152
141regulation of glucokinase activity (GO:0033131)2.62690152
142negative regulation of cytosolic calcium ion concentration (GO:0051481)2.62027988
143glycerophospholipid catabolic process (GO:0046475)2.61510799
144nodal signaling pathway (GO:0038092)2.61010207
145regulation of male gonad development (GO:2000018)2.60942322
146extracellular matrix assembly (GO:0085029)2.59935665
147COPI coating of Golgi vesicle (GO:0048205)2.59627517
148Golgi transport vesicle coating (GO:0048200)2.59627517
149positive regulation of glycolytic process (GO:0045821)2.59459341
150negative chemotaxis (GO:0050919)2.58214054
151regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.57331965
152bone trabecula formation (GO:0060346)2.55043641
153negative regulation of activin receptor signaling pathway (GO:0032926)2.52287325
154mesenchymal-epithelial cell signaling (GO:0060638)2.51992772
155regulation of gonadotropin secretion (GO:0032276)2.51533866
156type B pancreatic cell development (GO:0003323)2.51146557
157UDP-N-acetylglucosamine metabolic process (GO:0006047)2.49121266
158estrogen biosynthetic process (GO:0006703)2.49049719
159positive regulation of nitric-oxide synthase activity (GO:0051000)2.47552101
160activin receptor signaling pathway (GO:0032924)2.47431502
161extracellular negative regulation of signal transduction (GO:1900116)2.47188015
162extracellular regulation of signal transduction (GO:1900115)2.47188015
163regulation of axon guidance (GO:1902667)2.45714666
164polarized epithelial cell differentiation (GO:0030859)2.45298262
165negative regulation of osteoblast proliferation (GO:0033689)2.44817604
166regulation of steroid hormone biosynthetic process (GO:0090030)2.44787232
167vesicle coating (GO:0006901)2.42445502
168positive regulation of amine transport (GO:0051954)2.41819219
169paraxial mesoderm development (GO:0048339)2.41627095
170wound healing, spreading of cells (GO:0044319)2.41543581
171neuron projection extension (GO:1990138)2.38267822
172heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.33405674
173proteoglycan biosynthetic process (GO:0030166)2.31781289
174inner ear receptor cell development (GO:0060119)2.31182796
175anterior/posterior axis specification, embryo (GO:0008595)2.30029482
176behavioral response to ethanol (GO:0048149)2.28286820
177peptide hormone processing (GO:0016486)2.28266031
178endocrine pancreas development (GO:0031018)2.28158363
179androgen biosynthetic process (GO:0006702)2.26931112
180insulin secretion (GO:0030073)2.26431735
181glomerular visceral epithelial cell development (GO:0072015)2.25820572
182regulation of cAMP-dependent protein kinase activity (GO:2000479)2.25656171
183growth hormone secretion (GO:0030252)2.25576254
184Leydig cell differentiation (GO:0033327)2.25485856
185lymphangiogenesis (GO:0001946)2.25090061
186response to gravity (GO:0009629)2.23211006
187glucocorticoid metabolic process (GO:0008211)2.22934103
188negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.22789312
189actin filament depolymerization (GO:0030042)2.20408152
190urinary tract smooth muscle contraction (GO:0014848)2.20319479
191negative regulation of glycogen metabolic process (GO:0070874)2.19866986

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.15128521
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.67872507
3GBX2_23144817_ChIP-Seq_PC3_Human3.83906736
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.06859403
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02457686
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.96490459
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.76586375
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.69354133
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.68978259
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.68978259
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.64417529
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.57454458
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.55248394
14WT1_19549856_ChIP-ChIP_CCG9911_Human2.52553050
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50899282
16TAF15_26573619_Chip-Seq_HEK293_Human2.47690458
17TRIM28_21343339_ChIP-Seq_HEK293_Human2.44018453
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.41238276
19REST_21632747_ChIP-Seq_MESCs_Mouse2.34827430
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.29009951
21PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.28275478
22* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26432689
23CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18843015
24ZFP57_27257070_Chip-Seq_ESCs_Mouse2.11809983
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.09369565
26SUZ12_27294783_Chip-Seq_ESCs_Mouse2.07547602
27EZH2_27294783_Chip-Seq_ESCs_Mouse2.07494466
28CTBP1_25329375_ChIP-Seq_LNCAP_Human2.06990282
29ZNF274_21170338_ChIP-Seq_K562_Hela2.04278469
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.01041073
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.93549979
32BRD4_25478319_ChIP-Seq_HGPS_Human1.93191477
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.93168455
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89220912
35EP300_21415370_ChIP-Seq_HL-1_Mouse1.88509691
36ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.83875106
37HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.80709581
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.80686545
39BMI1_23680149_ChIP-Seq_NPCS_Mouse1.80580499
40REST_18959480_ChIP-ChIP_MESCs_Mouse1.79568331
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.72242508
42CJUN_26792858_Chip-Seq_BT549_Human1.71960882
43SMAD4_21799915_ChIP-Seq_A2780_Human1.71571963
44P300_19829295_ChIP-Seq_ESCs_Human1.71201646
45RARB_27405468_Chip-Seq_BRAIN_Mouse1.69843142
46FUS_26573619_Chip-Seq_HEK293_Human1.68695795
47IGF1R_20145208_ChIP-Seq_DFB_Human1.66279153
48IKZF1_21737484_ChIP-ChIP_HCT116_Human1.65989394
49CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.65143780
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.63261661
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.61877581
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.60820029
53NRF2_20460467_ChIP-Seq_MEFs_Mouse1.60299875
54NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.60299875
55SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59033507
56DROSHA_22980978_ChIP-Seq_HELA_Human1.57991482
57RNF2_27304074_Chip-Seq_NSC_Mouse1.56897227
58AR_21572438_ChIP-Seq_LNCaP_Human1.56605678
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.54753839
60OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.50556672
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.47066424
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.46933240
63PCGF2_27294783_Chip-Seq_ESCs_Mouse1.46544296
64POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45461541
65FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.43912760
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.39757205
67MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39588374
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39108968
69SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35887663
70AR_25329375_ChIP-Seq_VCAP_Human1.34991894
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.34569354
72PCGF2_27294783_Chip-Seq_NPCs_Mouse1.33403900
73NR3C1_23031785_ChIP-Seq_PC12_Mouse1.33389954
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32852850
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.32514299
76EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.32217514
77SOX2_21211035_ChIP-Seq_LN229_Gbm1.31849129
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30358292
79RING1B_27294783_Chip-Seq_ESCs_Mouse1.30053467
80* EZH2_27294783_Chip-Seq_NPCs_Mouse1.29354230
81JUN_21703547_ChIP-Seq_K562_Human1.23655609
82CDX2_19796622_ChIP-Seq_MESCs_Mouse1.23571093
83VDR_22108803_ChIP-Seq_LS180_Human1.23439750
84UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22363372
85ERG_21242973_ChIP-ChIP_JURKAT_Human1.21114116
86EWS_26573619_Chip-Seq_HEK293_Human1.20016758
87TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18296309
88* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17792414
89ARNT_22903824_ChIP-Seq_MCF-7_Human1.17713092
90TP53_18474530_ChIP-ChIP_U2OS_Human1.16793060
91RING1B_27294783_Chip-Seq_NPCs_Mouse1.16197261
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.14527927
93STAT3_23295773_ChIP-Seq_U87_Human1.14376217
94BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.13532080
95LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12158867
96STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.12100172
97ER_23166858_ChIP-Seq_MCF-7_Human1.10711420
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10379470
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10379470
100SMAD_19615063_ChIP-ChIP_OVARY_Human1.10240016
101TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.09883453
102NFE2_27457419_Chip-Seq_LIVER_Mouse1.09376879
103TBX3_20139965_ChIP-Seq_MESCs_Mouse1.09072655
104YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09064006
105* RUNX2_22187159_ChIP-Seq_PCA_Human1.08958683
106AHR_22903824_ChIP-Seq_MCF-7_Human1.08703421
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08454356
108TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08397119
109GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08023801
110AR_19668381_ChIP-Seq_PC3_Human1.07588814
111TBX3_20139965_ChIP-Seq_ESCs_Mouse1.07347731
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07303327
113P53_22387025_ChIP-Seq_ESCs_Mouse1.04886789
114EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04410089
115TP53_20018659_ChIP-ChIP_R1E_Mouse1.04283457
116TCF4_23295773_ChIP-Seq_U87_Human1.03953393
117WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.03641217
118SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.03536832
119IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.03261396
120NANOG_18555785_Chip-Seq_ESCs_Mouse1.02202279
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01966805
122ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00138837
123PRDM14_20953172_ChIP-Seq_ESCs_Human0.99635659
124KDM2B_26808549_Chip-Seq_REH_Human0.99427763
125MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.97624934
126KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.97356969
127SMAD3_21741376_ChIP-Seq_ESCs_Human0.97304533
128TP53_16413492_ChIP-PET_HCT116_Human0.97135646
129CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96442768
130BCAT_22108803_ChIP-Seq_LS180_Human0.93092419
131TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.92255904
132SOX9_26525672_Chip-Seq_HEART_Mouse0.92135879
133NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91672381
134CBP_20019798_ChIP-Seq_JUKART_Human0.91662465

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.12848548
2MP0004859_abnormal_synaptic_plasticity5.11278561
3MP0003880_abnormal_central_pattern4.41784705
4MP0003635_abnormal_synaptic_transmissio3.47055759
5MP0004270_analgesia3.45512241
6MP0001968_abnormal_touch/_nociception3.28174821
7MP0005275_abnormal_skin_tensile3.04543740
8MP0002735_abnormal_chemical_nociception3.00314420
9MP0002063_abnormal_learning/memory/cond2.95314150
10MP0005257_abnormal_intraocular_pressure2.87798602
11MP0009745_abnormal_behavioral_response2.83251280
12MP0003279_aneurysm2.81397935
13MP0002736_abnormal_nociception_after2.80595311
14MP0004272_abnormal_basement_membrane2.66782499
15MP0006276_abnormal_autonomic_nervous2.61980874
16MP0002734_abnormal_mechanical_nocicepti2.52940806
17MP0002572_abnormal_emotion/affect_behav2.52348787
18MP0002064_seizures2.49032577
19MP0005423_abnormal_somatic_nervous2.35097671
20MP0008877_abnormal_DNA_methylation2.32459260
21MP0000778_abnormal_nervous_system2.27760446
22MP0009384_cardiac_valve_regurgitation2.27071153
23MP0002733_abnormal_thermal_nociception2.25419779
24MP0010368_abnormal_lymphatic_system2.16472493
25MP0002184_abnormal_innervation2.14687958
26MP0002272_abnormal_nervous_system2.13858681
27MP0001440_abnormal_grooming_behavior2.09822976
28MP0001529_abnormal_vocalization2.08323664
29MP0001970_abnormal_pain_threshold2.06509231
30MP0006054_spinal_hemorrhage2.03323507
31MP0001958_emphysema2.03059674
32MP0001501_abnormal_sleep_pattern2.00960581
33MP0001486_abnormal_startle_reflex1.99001927
34MP0003122_maternal_imprinting1.95514555
35MP0002254_reproductive_system_inflammat1.93565735
36MP0009046_muscle_twitch1.90298800
37MP0001542_abnormal_bone_strength1.90252075
38MP0004858_abnormal_nervous_system1.88266266
39MP0008004_abnormal_stomach_pH1.87602691
40MP0002067_abnormal_sensory_capabilities1.85956054
41MP0002822_catalepsy1.83448524
42MP0003705_abnormal_hypodermis_morpholog1.82757630
43MP0003941_abnormal_skin_development1.81508224
44MP0000462_abnormal_digestive_system1.80039246
45MP0003787_abnormal_imprinting1.77164228
46MP0002557_abnormal_social/conspecific_i1.73918418
47MP0009780_abnormal_chondrocyte_physiolo1.68016939
48MP0010352_gastrointestinal_tract_polyps1.67841756
49MP0001188_hyperpigmentation1.64218081
50MP0004811_abnormal_neuron_physiology1.60700523
51MP0005508_abnormal_skeleton_morphology1.53785877
52MP0003329_amyloid_beta_deposits1.51585364
53MP0004924_abnormal_behavior1.51417794
54MP0005386_behavior/neurological_phenoty1.51417794
55MP0005187_abnormal_penis_morphology1.49149030
56MP0000955_abnormal_spinal_cord1.47226578
57MP0002896_abnormal_bone_mineralization1.45925281
58MP0003566_abnormal_cell_adhesion1.42990004
59MP0004134_abnormal_chest_morphology1.41841613
60MP0006072_abnormal_retinal_apoptosis1.41057437
61MP0002882_abnormal_neuron_morphology1.40526420
62MP0001984_abnormal_olfaction1.37795260
63MP0002909_abnormal_adrenal_gland1.36402867
64MP0003879_abnormal_hair_cell1.31440274
65MP0002295_abnormal_pulmonary_circulatio1.29162785
66MP0002060_abnormal_skin_morphology1.29118183
67MP0010386_abnormal_urinary_bladder1.28806871
68MP0001905_abnormal_dopamine_level1.26695330
69MP0000003_abnormal_adipose_tissue1.24720188
70MP0003123_paternal_imprinting1.24201428
71MP0002837_dystrophic_cardiac_calcinosis1.23993994
72MP0003950_abnormal_plasma_membrane1.23101998
73MP0002066_abnormal_motor_capabilities/c1.21793932
74MP0000538_abnormal_urinary_bladder1.17180717
75MP0002152_abnormal_brain_morphology1.15250150
76MP0000631_abnormal_neuroendocrine_gland1.14335964
77MP0004233_abnormal_muscle_weight1.12913296
78MP0005623_abnormal_meninges_morphology1.11884445
79MP0008569_lethality_at_weaning1.11849791
80MP0000569_abnormal_digit_pigmentation1.11548217
81MP0000751_myopathy1.09207468
82MP0002751_abnormal_autonomic_nervous1.07346249
83MP0001944_abnormal_pancreas_morphology1.07161443
84MP0002876_abnormal_thyroid_physiology1.04926080
85MP0001299_abnormal_eye_distance/1.04440250
86MP0002638_abnormal_pupillary_reflex1.01386255
87MP0000767_abnormal_smooth_muscle1.01174710
88MP0002102_abnormal_ear_morphology1.01023070
89MP0003718_maternal_effect0.99235975
90MP0003121_genomic_imprinting0.97241196
91MP0005646_abnormal_pituitary_gland0.96394770
92MP0001502_abnormal_circadian_rhythm0.95011554
93MP0005645_abnormal_hypothalamus_physiol0.94485333
94MP0001243_abnormal_dermal_layer0.94458605
95MP0000639_abnormal_adrenal_gland0.94389559
96MP0002108_abnormal_muscle_morphology0.93513229
97MP0003868_abnormal_feces_composition0.92794694
98MP0002752_abnormal_somatic_nervous0.92298054
99MP0005394_taste/olfaction_phenotype0.90978105
100MP0005499_abnormal_olfactory_system0.90978105
101MP0005595_abnormal_vascular_smooth0.90873910
102MP0008789_abnormal_olfactory_epithelium0.89981673
103MP0003385_abnormal_body_wall0.89707421
104MP0003861_abnormal_nervous_system0.87312464
105MP0002069_abnormal_eating/drinking_beha0.86805891
106MP0004885_abnormal_endolymph0.86728260
107MP0003890_abnormal_embryonic-extraembry0.84735815
108MP0004742_abnormal_vestibular_system0.84271269
109MP0004142_abnormal_muscle_tone0.84165434
110MP0001963_abnormal_hearing_physiology0.83518337
111MP0005551_abnormal_eye_electrophysiolog0.82991501
112MP0004133_heterotaxia0.82732822
113MP0000534_abnormal_ureter_morphology0.82465162
114MP0004085_abnormal_heartbeat0.82422443
115MP0003119_abnormal_digestive_system0.81890237
116MP0003283_abnormal_digestive_organ0.81187454
117MP0003091_abnormal_cell_migration0.81149382
118MP0002177_abnormal_outer_ear0.80200671
119MP0003633_abnormal_nervous_system0.79412733
120MP0005023_abnormal_wound_healing0.79216034
121MP0003942_abnormal_urinary_system0.78747932
122MP0003937_abnormal_limbs/digits/tail_de0.78278473
123MP0009379_abnormal_foot_pigmentation0.77754326
124MP0002234_abnormal_pharynx_morphology0.76738112
125MP0000026_abnormal_inner_ear0.76215263
126MP0001664_abnormal_digestion0.75954294
127MP0003195_calcinosis0.75406677
128MP0003631_nervous_system_phenotype0.74946401
129MP0003137_abnormal_impulse_conducting0.74853055
130MP0003938_abnormal_ear_development0.73859003
131MP0000163_abnormal_cartilage_morphology0.73759578
132MP0000013_abnormal_adipose_tissue0.72812947
133MP0004145_abnormal_muscle_electrophysio0.72576256
134MP0000230_abnormal_systemic_arterial0.71451544
135MP0001756_abnormal_urination0.71175536
136MP0003634_abnormal_glial_cell0.69831659
137MP0001943_abnormal_respiration0.67837801
138MP0005503_abnormal_tendon_morphology0.67076880
139MP0001177_atelectasis0.66233847
140MP0002115_abnormal_skeleton_extremities0.65934952
141MP0003755_abnormal_palate_morphology0.65339489
142MP0005390_skeleton_phenotype0.64741254
143MP0008961_abnormal_basal_metabolism0.64581981
144MP0000428_abnormal_craniofacial_morphol0.64254821
145MP0001879_abnormal_lymphatic_vessel0.64201200
146MP0009250_abnormal_appendicular_skeleto0.64134699
147MP0003315_abnormal_perineum_morphology0.64032884
148MP0002229_neurodegeneration0.63766716
149MP0000537_abnormal_urethra_morphology0.62637947
150MP0002693_abnormal_pancreas_physiology0.62529186
151MP0005395_other_phenotype0.62219314
152MP0002938_white_spotting0.60890329
153MP0000681_abnormal_thyroid_gland0.60436266
154MP0000049_abnormal_middle_ear0.59998147
155MP0008874_decreased_physiological_sensi0.59403508
156MP0010030_abnormal_orbit_morphology0.57498169
157MP0002109_abnormal_limb_morphology0.56423872
158MP0000427_abnormal_hair_cycle0.56336155
159MP0002928_abnormal_bile_duct0.55899501
160MP0002160_abnormal_reproductive_system0.55253005
161MP0000432_abnormal_head_morphology0.55213865
162MP0005389_reproductive_system_phenotype0.54375059

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.15840453
2Premature rupture of membranes (HP:0001788)6.14688227
3Focal seizures (HP:0007359)5.21045188
4Protrusio acetabuli (HP:0003179)5.20879319
5Myokymia (HP:0002411)4.82200990
6Visual hallucinations (HP:0002367)4.53492234
7Atonic seizures (HP:0010819)4.40155431
8Absence seizures (HP:0002121)4.33793784
9Epileptic encephalopathy (HP:0200134)4.26093106
10Abnormality of dentin (HP:0010299)4.14155118
11Follicular hyperkeratosis (HP:0007502)4.10924899
12Ankle contracture (HP:0006466)4.04926468
13Febrile seizures (HP:0002373)3.79534627
14Dialeptic seizures (HP:0011146)3.75699612
15Aortic dissection (HP:0002647)3.68580029
16Wrist flexion contracture (HP:0001239)3.62278303
17Hyperventilation (HP:0002883)3.50378634
18Atrophic scars (HP:0001075)3.47355337
19Soft skin (HP:0000977)3.38407788
20Genu recurvatum (HP:0002816)3.30376044
21Broad metatarsal (HP:0001783)3.26376933
22Progressive cerebellar ataxia (HP:0002073)3.25467749
23Spinal rigidity (HP:0003306)3.25049859
24Bladder diverticulum (HP:0000015)3.17442476
25Broad-based gait (HP:0002136)3.13288953
26Aortic aneurysm (HP:0004942)3.13166901
27Amblyopia (HP:0000646)3.11019152
28Generalized tonic-clonic seizures (HP:0002069)3.08273722
29Insidious onset (HP:0003587)2.97830748
30Termporal pattern (HP:0011008)2.97830748
31Excessive salivation (HP:0003781)2.92228711
32Drooling (HP:0002307)2.92228711
33Wormian bones (HP:0002645)2.87068850
34Enlarged penis (HP:0000040)2.84691062
35Type 1 muscle fiber predominance (HP:0003803)2.83891767
36Action tremor (HP:0002345)2.83097518
37Vascular tortuosity (HP:0004948)2.79504442
38Overgrowth (HP:0001548)2.78355107
39Neonatal short-limb short stature (HP:0008921)2.75989567
40Relative macrocephaly (HP:0004482)2.75229360
41Truncal ataxia (HP:0002078)2.68322438
42Bowel diverticulosis (HP:0005222)2.68228877
43Hypoglycemic seizures (HP:0002173)2.64192046
44Pheochromocytoma (HP:0002666)2.61495445
45Limb dystonia (HP:0002451)2.60025860
46Slender build (HP:0001533)2.58927455
47Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.57311696
48Absent speech (HP:0001344)2.55193703
49Gait imbalance (HP:0002141)2.54241236
50Hypoplasia of the brainstem (HP:0002365)2.49947410
51Aplasia/Hypoplasia of the brainstem (HP:0007362)2.49947410
52Supranuclear gaze palsy (HP:0000605)2.49487341
53Cervical subluxation (HP:0003308)2.48870624
54Peritonitis (HP:0002586)2.47938852
55Cerebral inclusion bodies (HP:0100314)2.46158313
56Agitation (HP:0000713)2.37470405
57Cardiovascular calcification (HP:0011915)2.37362743
58Hypoventilation (HP:0002791)2.35134197
59Fragile skin (HP:0001030)2.34180910
60Progressive inability to walk (HP:0002505)2.33607638
61Arterial tortuosity (HP:0005116)2.31771883
62Poor eye contact (HP:0000817)2.30680734
63Delayed gross motor development (HP:0002194)2.30160123
64Hyperthyroidism (HP:0000836)2.29612103
65Exotropia (HP:0000577)2.28098712
66Anterior segment dysgenesis (HP:0007700)2.27357309
67Hypoglycemic coma (HP:0001325)2.27271237
68Limb-girdle muscle weakness (HP:0003325)2.25365122
69Mitral stenosis (HP:0001718)2.25200784
70Neuroendocrine neoplasm (HP:0100634)2.22478824
71Aqueductal stenosis (HP:0002410)2.21807885
72Impaired social interactions (HP:0000735)2.21151050
73Abnormal social behavior (HP:0012433)2.21151050
74Hyperglycemia (HP:0003074)2.21005089
75Shallow orbits (HP:0000586)2.18921567
76Striae distensae (HP:0001065)2.18453367
77Ankle clonus (HP:0011448)2.17408759
78Hyperextensible skin (HP:0000974)2.16200663
79Aortic valve stenosis (HP:0001650)2.15997912
80Amyotrophic lateral sclerosis (HP:0007354)2.15573715
81Epileptiform EEG discharges (HP:0011182)2.14724278
82Depression (HP:0000716)2.13739906
83Spondylolisthesis (HP:0003302)2.13452323
84Hyperinsulinemic hypoglycemia (HP:0000825)2.10221096
85Heterochromia iridis (HP:0001100)2.09781015
86Abnormal hair whorl (HP:0010721)2.08753481
87Impaired vibration sensation in the lower limbs (HP:0002166)2.08562471
88Abnormality of salivation (HP:0100755)2.08367721
89Abnormality of the corticospinal tract (HP:0002492)2.06751701
90Hydroureter (HP:0000072)2.06105388
91Congenital primary aphakia (HP:0007707)2.05211251
92Mutism (HP:0002300)2.05171187
93Abnormal pancreas size (HP:0012094)2.04099035
94Inability to walk (HP:0002540)2.04085329
95Buphthalmos (HP:0000557)2.03952709
96Congenital glaucoma (HP:0001087)2.03379986
97Polyphagia (HP:0002591)2.03185543
98Medial flaring of the eyebrow (HP:0010747)2.02570012
99Coronal craniosynostosis (HP:0004440)2.02326637
100Protruding tongue (HP:0010808)2.02261400
101Joint laxity (HP:0001388)2.02217724
102EEG with generalized epileptiform discharges (HP:0011198)2.01479675
103Specific learning disability (HP:0001328)2.00429780
104Gaze-evoked nystagmus (HP:0000640)1.99822886
105Metaphyseal dysplasia (HP:0100255)1.98781954
106Genital tract atresia (HP:0001827)1.98070353
107Mildly elevated creatine phosphokinase (HP:0008180)1.97986126
108Fetal akinesia sequence (HP:0001989)1.97921053
109Ovoid vertebral bodies (HP:0003300)1.97071654
110Limited hip movement (HP:0008800)1.96769844
111Abnormality of carpal bone ossification (HP:0006257)1.96766451
112Anxiety (HP:0000739)1.95344958
113Urinary bladder sphincter dysfunction (HP:0002839)1.94968228
114Impaired pain sensation (HP:0007328)1.93536368
115Abnormality of pain sensation (HP:0010832)1.93536368
116Aortic regurgitation (HP:0001659)1.92952247
117Vaginal atresia (HP:0000148)1.92165432
118Round ear (HP:0100830)1.91580459
119Abnormality of the acetabulum (HP:0003170)1.90570306
120Unilateral renal agenesis (HP:0000122)1.90074649
121Mild short stature (HP:0003502)1.89677682
122Failure to thrive in infancy (HP:0001531)1.89245007
123Lissencephaly (HP:0001339)1.89162114
124Hypsarrhythmia (HP:0002521)1.88034992
125Urinary urgency (HP:0000012)1.87200570
126Abnormal eating behavior (HP:0100738)1.86553400
127Neurofibrillary tangles (HP:0002185)1.86288490
128Poor suck (HP:0002033)1.85917241
129Abnormality of abdominal situs (HP:0011620)1.85638599
130Abdominal situs inversus (HP:0003363)1.85638599
131Abnormality of the lower motor neuron (HP:0002366)1.85202173
132Impaired smooth pursuit (HP:0007772)1.83165281
133Insulin-resistant diabetes mellitus (HP:0000831)1.82472161
134Mitral valve prolapse (HP:0001634)1.82295078
135Ulnar claw (HP:0001178)1.82249376
136Abnormality of calcium-phosphate metabolism (HP:0100530)1.82083165
137Broad ribs (HP:0000885)1.81724514
138Papilledema (HP:0001085)1.81598470
139Blue irides (HP:0000635)1.81525115
140Dynein arm defect of respiratory motile cilia (HP:0012255)1.80743874
141Absent/shortened dynein arms (HP:0200106)1.80743874
142Persistence of primary teeth (HP:0006335)1.80152266
143Femoral bowing (HP:0002980)1.80100964
144Abnormal delivery (HP:0001787)1.79476077
145Joint stiffness (HP:0001387)1.79315078
146Hyperphosphatemia (HP:0002905)1.78417471
147Nephrogenic diabetes insipidus (HP:0009806)1.77671787
148Blue sclerae (HP:0000592)1.75512688
149Ectopia lentis (HP:0001083)1.74489987
150Dysdiadochokinesis (HP:0002075)1.73584480
151Insulin resistance (HP:0000855)1.73350026
152Hypothermia (HP:0002045)1.73323885
153Hemiparesis (HP:0001269)1.71607158
154Shoulder girdle muscle weakness (HP:0003547)1.70160493
155Hypercortisolism (HP:0001578)1.70109610
156Osteoarthritis (HP:0002758)1.70012451
157Abnormality of the anterior chamber (HP:0000593)1.69473578
158Narrow nasal bridge (HP:0000446)1.68873307
159Generalized hypotonia (HP:0001290)1.68762760
160Neoplasm of the peripheral nervous system (HP:0100007)1.68683162
161Keratoconus (HP:0000563)1.67908729
162Increased corneal curvature (HP:0100692)1.67908729
163Proximal tubulopathy (HP:0000114)1.67855387
164Akinesia (HP:0002304)1.66341280
165Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.66196100
166Deviation of the hallux (HP:0010051)1.66179672
167Breech presentation (HP:0001623)1.65168926
168Abnormality of the musculature of the pelvis (HP:0001469)1.65039567
169Abnormality of the hip-girdle musculature (HP:0001445)1.65039567
170Hallux valgus (HP:0001822)1.64916652
171Urinary glycosaminoglycan excretion (HP:0003541)1.63983611
172Mucopolysacchariduria (HP:0008155)1.63983611
173Sacral dimple (HP:0000960)1.63973643
174Delusions (HP:0000746)1.63886023
175Increased number of teeth (HP:0011069)1.63705821
176Lower limb muscle weakness (HP:0007340)1.63679063
177Neoplasm of the heart (HP:0100544)1.63191025
178Rapidly progressive (HP:0003678)1.62392058
179Inappropriate behavior (HP:0000719)1.62323484
180Dysmetria (HP:0001310)1.61993925
181Psychosis (HP:0000709)1.61833413
182Aplasia/Hypoplasia of the lens (HP:0008063)1.61218716
183Abnormality of ocular smooth pursuit (HP:0000617)1.61098153
184Bradycardia (HP:0001662)1.61042231
185Abnormality of the pulmonary veins (HP:0011718)1.59946669
186Thoracolumbar scoliosis (HP:0002944)1.58089125
187Osteopenia (HP:0000938)1.57595974
188Long toe (HP:0010511)1.57227319
189Hip contracture (HP:0003273)1.56987853
190Vascular calcification (HP:0004934)1.55478276
191Flared iliac wings (HP:0002869)1.54870307
192Wide anterior fontanel (HP:0000260)1.54754439
193Symptomatic seizures (HP:0011145)1.54674845

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.17299728
2MARK13.85592588
3FRK3.65117734
4CASK3.26239035
5EPHA43.15547476
6MAP3K93.05114004
7MINK12.87940116
8MYLK2.86329726
9MAP3K42.83529469
10PINK12.83321862
11MAP3K122.56309282
12MAP2K72.46822102
13PLK22.35430799
14GRK52.30366112
15KSR12.09196254
16PTK22.02236690
17RIPK41.95396196
18LATS21.92824015
19PAK61.91314608
20STK38L1.86157471
21NTRK21.85579548
22MAPK131.77285913
23MAP2K41.76089138
24PNCK1.74767299
25STK31.69088730
26KSR21.65584336
27TRPM71.62044783
28NTRK11.59364737
29SIK31.57739626
30DAPK21.54588238
31FLT31.41793113
32SIK21.41757983
33LATS11.41298378
34PRKD31.38738931
35NEK91.37553075
36GRK11.36999740
37PTK2B1.34936522
38MAP4K21.34633033
39CDK51.32951584
40PRKD21.29657782
41ERBB31.25803534
42MET1.23628892
43PASK1.20750665
44DYRK21.18323652
45UHMK11.18254273
46PAK31.17269043
47PRKCG1.15218886
48CDK141.13992451
49PAK21.12928692
50BCR1.12275126
51CDK181.11823958
52CAMK2A1.11580868
53AKT31.08499422
54MST41.06352996
55PIK3CG1.05573627
56DYRK31.04159775
57BMPR1B1.03799574
58CSNK1G21.03346026
59FGFR21.02321613
60CDK151.02220046
61MAP3K21.01370793
62DAPK11.00621152
63EPHB20.99708176
64LIMK10.98775309
65CDK80.98774185
66ARAF0.96035573
67CSNK1G10.95986995
68CAMK2B0.94029803
69DDR20.90225665
70NUAK10.88960234
71CDK11A0.87608804
72NME10.85545829
73PHKG10.84973271
74PHKG20.84973271
75FER0.82077546
76PDGFRB0.80936623
77WNK30.80072292
78CDC42BPA0.79322313
79RET0.78077555
80TYRO30.75599783
81PRPF4B0.74493584
82GSK3A0.73817393
83PRKG20.73192966
84DYRK1A0.72964059
85CAMKK10.72482406
86TIE10.71930987
87MAP2K10.70551276
88PRKCE0.70138907
89PLK40.68188849
90EPHB10.67590010
91SGK4940.67302601
92SGK2230.67302601
93ACVR1B0.66099056
94PRKCH0.65815481
95CSNK1G30.64870835
96BMPR20.62097738
97TNIK0.61363969
98ERBB40.59810487
99MAP2K20.58957334
100CAMKK20.58774817
101FGR0.57806835
102PDK40.55635558
103PDK30.55635558
104RPS6KA20.55529452
105CDK90.54878270
106STK240.53292971
107RAF10.53147396
108STK110.52598495
109ADRBK10.51453549
110STK380.51311649
111PAK40.51247055
112ROCK20.51243372
113EIF2AK30.50872184
114TTN0.49635804
115WNK40.49490607
116PRKAA10.48891528
117PDGFRA0.48758233
118CAMK2D0.48339492
119PRKCZ0.48192737
120JAK10.47567061
121PIK3CA0.47426740
122WNK10.47238440
123SGK10.46627094
124CSNK1D0.45119155
125DAPK30.44821293
126NLK0.43119943
127YES10.42746315
128MAP3K60.42174636
129GRK70.41782405
130INSRR0.41109959
131FES0.39807751
132MOS0.37935766
133FYN0.37792102
134ROCK10.37286119
135DMPK0.36973592
136TRIM280.36891200
137SGK20.36546895
138CSNK1A1L0.36228101
139TESK10.35412310
140STK390.35056960
141MARK20.34705831
142MAPK100.33001319
143PLK30.32747828
144CCNB10.32655402
145ADRBK20.32447324
146TAOK10.31957363
147RPS6KA30.31856663
148CAMK10.30740973
149CDK190.30106456

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.23299189
2Nicotine addiction_Homo sapiens_hsa050333.75408639
3Synaptic vesicle cycle_Homo sapiens_hsa047212.99479125
4Protein export_Homo sapiens_hsa030602.62785242
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.57540296
6Circadian entrainment_Homo sapiens_hsa047132.50746933
7Long-term potentiation_Homo sapiens_hsa047202.41873578
8Glutamatergic synapse_Homo sapiens_hsa047242.39395103
9GABAergic synapse_Homo sapiens_hsa047272.32050328
10ECM-receptor interaction_Homo sapiens_hsa045122.27585015
11Amphetamine addiction_Homo sapiens_hsa050312.23732276
12Dopaminergic synapse_Homo sapiens_hsa047282.21666306
13Morphine addiction_Homo sapiens_hsa050322.17991504
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.17718622
15Olfactory transduction_Homo sapiens_hsa047401.95592563
16Salivary secretion_Homo sapiens_hsa049701.94946091
17Serotonergic synapse_Homo sapiens_hsa047261.93114726
18Long-term depression_Homo sapiens_hsa047301.90695256
19Collecting duct acid secretion_Homo sapiens_hsa049661.85904459
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.84244229
21Sulfur metabolism_Homo sapiens_hsa009201.83754379
22Taste transduction_Homo sapiens_hsa047421.78977055
23Cholinergic synapse_Homo sapiens_hsa047251.76180252
24Glycosaminoglycan degradation_Homo sapiens_hsa005311.74649740
25Insulin secretion_Homo sapiens_hsa049111.72873028
26Axon guidance_Homo sapiens_hsa043601.72643196
27Protein digestion and absorption_Homo sapiens_hsa049741.64936956
28Cocaine addiction_Homo sapiens_hsa050301.63102760
29Renin secretion_Homo sapiens_hsa049241.60692045
30Focal adhesion_Homo sapiens_hsa045101.58955852
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.57252925
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.57096268
33GnRH signaling pathway_Homo sapiens_hsa049121.54670119
34Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.53006920
35Gap junction_Homo sapiens_hsa045401.51551011
36Oxytocin signaling pathway_Homo sapiens_hsa049211.51442763
37Steroid biosynthesis_Homo sapiens_hsa001001.50747564
38Gastric acid secretion_Homo sapiens_hsa049711.48346073
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.47804508
40Calcium signaling pathway_Homo sapiens_hsa040201.41013350
41Vibrio cholerae infection_Homo sapiens_hsa051101.38836774
42Phototransduction_Homo sapiens_hsa047441.36288608
43Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.34794740
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.34742791
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.34619665
46TGF-beta signaling pathway_Homo sapiens_hsa043501.32813162
47Cardiac muscle contraction_Homo sapiens_hsa042601.31200575
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.27327243
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25477649
50Melanogenesis_Homo sapiens_hsa049161.19861520
51Glioma_Homo sapiens_hsa052141.15566884
52Butanoate metabolism_Homo sapiens_hsa006501.12683946
53Sphingolipid metabolism_Homo sapiens_hsa006001.12335274
54Estrogen signaling pathway_Homo sapiens_hsa049151.09517392
55Oxidative phosphorylation_Homo sapiens_hsa001901.08646165
56Alzheimers disease_Homo sapiens_hsa050101.04846956
57Oocyte meiosis_Homo sapiens_hsa041141.03357484
58ErbB signaling pathway_Homo sapiens_hsa040121.01036734
59N-Glycan biosynthesis_Homo sapiens_hsa005101.00186651
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99074891
61Proteoglycans in cancer_Homo sapiens_hsa052050.96537780
62cAMP signaling pathway_Homo sapiens_hsa040240.96319544
63Caffeine metabolism_Homo sapiens_hsa002320.95849317
64Regulation of actin cytoskeleton_Homo sapiens_hsa048100.95635562
65Dilated cardiomyopathy_Homo sapiens_hsa054140.93367634
66Circadian rhythm_Homo sapiens_hsa047100.91583698
67Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90223607
68Selenocompound metabolism_Homo sapiens_hsa004500.90032958
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.88999769
70Tight junction_Homo sapiens_hsa045300.88495139
71Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87395810
72Thyroid hormone synthesis_Homo sapiens_hsa049180.86345497
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.84602992
74Ovarian steroidogenesis_Homo sapiens_hsa049130.83418307
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83077796
76Adherens junction_Homo sapiens_hsa045200.80733487
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.80728442
78Parkinsons disease_Homo sapiens_hsa050120.80443537
79PI3K-Akt signaling pathway_Homo sapiens_hsa041510.80183558
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78159129
81Type II diabetes mellitus_Homo sapiens_hsa049300.78060152
82p53 signaling pathway_Homo sapiens_hsa041150.77356526
83Basal cell carcinoma_Homo sapiens_hsa052170.76197419
84Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75901533
85Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.75836412
86Wnt signaling pathway_Homo sapiens_hsa043100.72952367
87Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.71656666
88Rap1 signaling pathway_Homo sapiens_hsa040150.71019067
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70809142
90VEGF signaling pathway_Homo sapiens_hsa043700.70275264
91Renin-angiotensin system_Homo sapiens_hsa046140.70036688
92Choline metabolism in cancer_Homo sapiens_hsa052310.68310639
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.68234786
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.68165805
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67648857
96MAPK signaling pathway_Homo sapiens_hsa040100.67354826
97Ras signaling pathway_Homo sapiens_hsa040140.66796884
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.66387566
99Hedgehog signaling pathway_Homo sapiens_hsa043400.66098208
100Huntingtons disease_Homo sapiens_hsa050160.64478817
101Pancreatic secretion_Homo sapiens_hsa049720.64450421
102Folate biosynthesis_Homo sapiens_hsa007900.63843259
103Colorectal cancer_Homo sapiens_hsa052100.62646791
104Vitamin B6 metabolism_Homo sapiens_hsa007500.62442683
105Ether lipid metabolism_Homo sapiens_hsa005650.62120624
106Alcoholism_Homo sapiens_hsa050340.61648899
107Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61550065
108Fatty acid elongation_Homo sapiens_hsa000620.60888952
109Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60106379
110Dorso-ventral axis formation_Homo sapiens_hsa043200.59269132
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59202723
112Amoebiasis_Homo sapiens_hsa051460.59110079
113Phagosome_Homo sapiens_hsa041450.55686397
114Melanoma_Homo sapiens_hsa052180.54048785
115Fat digestion and absorption_Homo sapiens_hsa049750.53854805
116Endometrial cancer_Homo sapiens_hsa052130.53078556
117Glucagon signaling pathway_Homo sapiens_hsa049220.52874920
118Hippo signaling pathway_Homo sapiens_hsa043900.52735880
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.52148764
120Pathways in cancer_Homo sapiens_hsa052000.50572300
121AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.49712637
122Prolactin signaling pathway_Homo sapiens_hsa049170.48789772
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.48636508
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48490268
125Galactose metabolism_Homo sapiens_hsa000520.48134066
126Basal transcription factors_Homo sapiens_hsa030220.46103357
127Endocytosis_Homo sapiens_hsa041440.45126585
128Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44351421
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43273392
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.42639635
131Renal cell carcinoma_Homo sapiens_hsa052110.42182115
132Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.41470692
133mTOR signaling pathway_Homo sapiens_hsa041500.41396099
134Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40801444
135Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40171309
136Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35847693
137Insulin signaling pathway_Homo sapiens_hsa049100.34411704
138Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33580343
139African trypanosomiasis_Homo sapiens_hsa051430.33498850
140Rheumatoid arthritis_Homo sapiens_hsa053230.32303162
141Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.31167958
142Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30566538

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