TMEM211

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline metabolic process (GO:0006560)8.75962277
2transcription from mitochondrial promoter (GO:0006390)8.46113375
3embryonic process involved in female pregnancy (GO:0060136)8.02932952
4replication fork processing (GO:0031297)7.72942295
5positive regulation of protein homooligomerization (GO:0032464)7.53303254
6establishment of apical/basal cell polarity (GO:0035089)6.92931569
7oxidative demethylation (GO:0070989)6.73558278
8regulation of integrin activation (GO:0033623)6.63506746
9regulation of protein homooligomerization (GO:0032462)6.42647525
10DNA deamination (GO:0045006)6.41818064
11maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)6.09597308
12establishment or maintenance of monopolar cell polarity (GO:0061339)6.07722337
13establishment of monopolar cell polarity (GO:0061162)6.07722337
14DNA strand renaturation (GO:0000733)5.61907001
15poly(A)+ mRNA export from nucleus (GO:0016973)5.56562119
16somatic hypermutation of immunoglobulin genes (GO:0016446)5.25534110
17somatic diversification of immune receptors via somatic mutation (GO:0002566)5.25534110
18negative regulation of JAK-STAT cascade (GO:0046426)5.13184673
19mitochondrial DNA metabolic process (GO:0032042)5.11242325
20embryonic placenta development (GO:0001892)4.91759430
21cellular response to ATP (GO:0071318)4.87700428
22viral mRNA export from host cell nucleus (GO:0046784)4.69469789
23negative regulation of Ras GTPase activity (GO:0034261)4.61298446
24mitotic G1 DNA damage checkpoint (GO:0031571)4.61063411
25glutamine family amino acid biosynthetic process (GO:0009084)4.60505098
26negative regulation of cell cycle arrest (GO:0071157)4.57985976
27mRNA cleavage (GO:0006379)4.53362868
28cellular response to zinc ion (GO:0071294)4.52370394
29negative regulation of protein oligomerization (GO:0032460)4.33347303
30glial cell migration (GO:0008347)4.30622330
31establishment of protein localization to mitochondrial membrane (GO:0090151)4.22279895
32negative regulation of fatty acid biosynthetic process (GO:0045717)4.19328282
33positive regulation of developmental pigmentation (GO:0048087)4.12098625
34DNA integration (GO:0015074)4.10278555
35G1 DNA damage checkpoint (GO:0044783)4.09113666
36positive regulation of protein oligomerization (GO:0032461)4.08255663
37face development (GO:0060324)4.07841494
38mitotic G1/S transition checkpoint (GO:0044819)4.05244566
39regulation of translational fidelity (GO:0006450)4.02605673
40convergent extension (GO:0060026)3.95902919
41regulation of protein oligomerization (GO:0032459)3.93815361
42negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.91463149
43DNA double-strand break processing (GO:0000729)3.90228010
44base-excision repair, AP site formation (GO:0006285)3.88715355
45spliceosomal tri-snRNP complex assembly (GO:0000244)3.88113176
46embryonic camera-type eye development (GO:0031076)3.87337984
47auditory receptor cell stereocilium organization (GO:0060088)3.87077131
48base-excision repair (GO:0006284)3.83614659
49sulfur amino acid catabolic process (GO:0000098)3.80994987
50negative regulation of chondrocyte differentiation (GO:0032331)3.80759626
51positive regulation by host of viral transcription (GO:0043923)3.76761861
52negative regulation of heart rate (GO:0010459)3.75367753
53pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.73726733
54double-strand break repair via nonhomologous end joining (GO:0006303)3.66032124
55non-recombinational repair (GO:0000726)3.66032124
56positive regulation of DNA repair (GO:0045739)3.65111998
57negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.62622301
58positive regulation of receptor recycling (GO:0001921)3.60154549
59L-ascorbic acid metabolic process (GO:0019852)3.53709930
60signal complex assembly (GO:0007172)3.52874349
61regulation of cAMP-dependent protein kinase activity (GO:2000479)3.52733065
62formation of translation preinitiation complex (GO:0001731)3.51945005
63alkaloid metabolic process (GO:0009820)3.49992573
64positive regulation of mitotic sister chromatid separation (GO:1901970)3.46696046
65positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.46696046
66positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.46696046
67anatomical structure regression (GO:0060033)3.44921973
68trophectodermal cell differentiation (GO:0001829)3.44800232
69regulation of RNA export from nucleus (GO:0046831)3.39265989
70histone H4-K12 acetylation (GO:0043983)3.38568596
71DNA ligation (GO:0006266)3.38324631
72labyrinthine layer development (GO:0060711)3.36272075
73negative regulation of cartilage development (GO:0061037)3.35524116
74regulation of mitochondrial depolarization (GO:0051900)3.35442725
75dosage compensation (GO:0007549)3.33105291
76apoptotic process involved in morphogenesis (GO:0060561)3.32883156
77DNA topological change (GO:0006265)3.30705954
78mitotic cell cycle arrest (GO:0071850)3.28798144
79negative regulation of mRNA processing (GO:0050686)3.27829995
80mitochondrial RNA metabolic process (GO:0000959)3.27821895
81regulation of sister chromatid cohesion (GO:0007063)3.25676598
82establishment of protein localization to vacuole (GO:0072666)3.23961520
83protein targeting to vacuole (GO:0006623)3.23961520
84protein targeting to lysosome (GO:0006622)3.23961520
85activation of Rac GTPase activity (GO:0032863)3.23767149
86telomere maintenance via semi-conservative replication (GO:0032201)3.19854327
87regulation of podosome assembly (GO:0071801)3.19502517
88negative regulation of response to food (GO:0032096)3.18834472
89negative regulation of appetite (GO:0032099)3.18834472
90GDP-mannose metabolic process (GO:0019673)3.15832930
91termination of RNA polymerase II transcription (GO:0006369)3.14346543
92embryonic eye morphogenesis (GO:0048048)3.13914649
93nucleotide-excision repair, DNA gap filling (GO:0006297)3.13141091
94hypotonic response (GO:0006971)3.12197410
95regulation of double-strand break repair via homologous recombination (GO:0010569)3.10577840
96mRNA polyadenylation (GO:0006378)3.05824887
97membrane invagination (GO:0010324)3.05399195
98pyrimidine nucleotide catabolic process (GO:0006244)3.04870355
99meiotic chromosome segregation (GO:0045132)3.04296318
100proline biosynthetic process (GO:0006561)11.5421372

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZFP281_18358816_ChIP-ChIP_MESCs_Mouse3.85481000
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.75119511
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.75119511
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.75119511
5SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.61548872
6RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.42740237
7SMAD3_22036565_ChIP-Seq_ESCs_Mouse3.13174224
8SOX2_18358816_ChIP-ChIP_MESCs_Mouse3.02594042
9NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.82730355
10NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.65774238
11CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.63353034
12POU5F1_16518401_ChIP-PET_MESCs_Mouse2.49464225
13ERG_21242973_ChIP-ChIP_JURKAT_Human2.47649034
14TCF3_18692474_ChIP-Seq_MESCs_Mouse2.34425978
15VDR_21846776_ChIP-Seq_THP-1_Human2.30423275
16KLF4_18358816_ChIP-ChIP_MESCs_Mouse2.30059248
17SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.18853708
18DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.17702766
19ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.15724459
20TCF3_18692474_ChIP-Seq_MEFs_Mouse2.08862191
21LXR_22292898_ChIP-Seq_THP-1_Human2.08841510
22NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.06504021
23POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.94717772
24ZNF263_19887448_ChIP-Seq_K562_Human1.85131670
25PU.1_20513432_ChIP-Seq_Bcells_Mouse1.82271030
26NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.82094161
27NANOG_21062744_ChIP-ChIP_HESCs_Human1.81198304
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80802075
29CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.80612689
30STAT3_1855785_ChIP-Seq_MESCs_Mouse1.79851063
31MYC_18555785_ChIP-Seq_MESCs_Mouse1.73701507
32RACK7_27058665_Chip-Seq_MCF-7_Human1.67731006
33ZFP281_27345836_Chip-Seq_ESCs_Mouse1.67548804
34ZFP281_18757296_ChIP-ChIP_E14_Mouse1.67071810
35ESR1_15608294_ChIP-ChIP_MCF-7_Human1.67048320
36TET1_21451524_ChIP-Seq_MESCs_Mouse1.60071798
37MYC_19079543_ChIP-ChIP_MESCs_Mouse1.56800441
38POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.53196252
39NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.52655932
40TP63_17297297_ChIP-ChIP_HaCaT_Human1.50732851
41CDX2_20551321_ChIP-Seq_CACO-2_Human1.48938569
42POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.47893059
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.45332205
44NANOG_18692474_ChIP-Seq_MESCs_Mouse1.44627308
45SOX2_18692474_ChIP-Seq_MESCs_Mouse1.41490319
46KDM2B_26808549_Chip-Seq_SUP-B15_Human1.40093765
47PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.37657212
48RXRA_24833708_ChIP-Seq_LIVER_Mouse1.36029424
49SOX2_18692474_ChIP-Seq_MEFs_Mouse1.35799881
50TRIM28_21343339_ChIP-Seq_HEK293_Human1.34484737
51RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.33466975
52KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29992302
53MYC_18358816_ChIP-ChIP_MESCs_Mouse1.29734726
54* PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.28573057
55SALL1_21062744_ChIP-ChIP_HESCs_Human1.28049736
56ETS1_21867929_ChIP-Seq_TH2_Mouse1.25525043
57TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.24881928
58KDM2B_26808549_Chip-Seq_DND41_Human1.24826959
59TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.24690017
60SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24038406
61RARB_24833708_ChIP-Seq_LIVER_Mouse1.23305398
62NANOG_16518401_ChIP-PET_MESCs_Mouse1.21453338
63KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.20969288
64TP53_20018659_ChIP-ChIP_R1E_Mouse1.20773113
65DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.20035866
66KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.17310347
67OCT4_18692474_ChIP-Seq_MEFs_Mouse1.16891306
68EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.15542475
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15077992
70SPI1_26923725_Chip-Seq_HPCs_Mouse1.14007412
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13819801
72NANOG_18555785_ChIP-Seq_MESCs_Mouse1.12415517
73CTCF_21964334_ChIP-Seq_BJAB-B_Human1.10948011
74RING1B_27294783_Chip-Seq_NPCs_Mouse1.10183328
75SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.09884821
76BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09296981
77RARA_24833708_ChIP-Seq_LIVER_Mouse1.09129003
78NANOG_18692474_ChIP-Seq_MEFs_Mouse1.09085401
79MYC_19030024_ChIP-ChIP_MESCs_Mouse1.08229968
80KDM2B_26808549_Chip-Seq_K562_Human1.08192804
81CTCF_27219007_Chip-Seq_ERYTHROID_Human1.07926692
82MYC_22102868_ChIP-Seq_BL_Human1.07280820
83STAT1_20625510_ChIP-Seq_HELA_Human1.07206139
84KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06934234
85EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.06747964
86ELK3_25401928_ChIP-Seq_HUVEC_Human1.06623940
87P300_27058665_Chip-Seq_ZR-75-30cells_Human1.06083410
88THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.05743955
89YY1_21170310_ChIP-Seq_MESCs_Mouse1.04632021
90CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.03289650
91E2F1_18555785_ChIP-Seq_MESCs_Mouse1.02347263
92STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.01830437
93* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.01318473
94ESR2_21235772_ChIP-Seq_MCF-7_Human0.99999143
95POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.98853242
96NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.97598984
97NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.95557229
98TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94764179
99FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.92993043
100CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92672360

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.82954873
2MP0005171_absent_coat_pigmentation5.11601391
3MP0010030_abnormal_orbit_morphology4.86333559
4MP0009278_abnormal_bone_marrow4.65652660
5MP0002009_preneoplasia3.87293494
6MP0004233_abnormal_muscle_weight3.64242949
7MP0008995_early_reproductive_senescence2.70581197
8MP0003890_abnormal_embryonic-extraembry2.58177922
9MP0002653_abnormal_ependyma_morphology2.44302926
10MP0002249_abnormal_larynx_morphology2.39628858
11MP0006072_abnormal_retinal_apoptosis2.33049443
12MP0001545_abnormal_hematopoietic_system2.12472958
13MP0005397_hematopoietic_system_phenotyp2.12472958
14MP0003786_premature_aging2.07524109
15MP0003453_abnormal_keratinocyte_physiol2.06076391
16MP0003283_abnormal_digestive_organ2.02756482
17MP0004133_heterotaxia1.99328205
18MP0000579_abnormal_nail_morphology1.90866385
19MP0005174_abnormal_tail_pigmentation1.87685672
20MP0003119_abnormal_digestive_system1.81542846
21MP0005499_abnormal_olfactory_system1.79374426
22MP0005394_taste/olfaction_phenotype1.79374426
23MP0002282_abnormal_trachea_morphology1.76791424
24MP0008789_abnormal_olfactory_epithelium1.72101723
25MP0000762_abnormal_tongue_morphology1.60224518
26MP0010094_abnormal_chromosome_stability1.58382865
27MP0005076_abnormal_cell_differentiation1.57523464
28MP0009053_abnormal_anal_canal1.51381264
29MP0001293_anophthalmia1.47100388
30MP0005085_abnormal_gallbladder_physiolo1.46275095
31MP0010352_gastrointestinal_tract_polyps1.38682472
32MP0000015_abnormal_ear_pigmentation1.37870977
33MP0003828_pulmonary_edema1.33538369
34MP0002086_abnormal_extraembryonic_tissu1.33442844
35MP0000462_abnormal_digestive_system1.31998087
36MP0002084_abnormal_developmental_patter1.30712698
37MP0001340_abnormal_eyelid_morphology1.27974693
38MP0000470_abnormal_stomach_morphology1.27742706
39MP0008058_abnormal_DNA_repair1.26824042
40MP0008877_abnormal_DNA_methylation1.24108400
41MP0000371_diluted_coat_color1.23604304
42MP0005365_abnormal_bile_salt1.23548715
43MP0002796_impaired_skin_barrier1.22279749
44MP0002085_abnormal_embryonic_tissue1.19286906
45MP0004264_abnormal_extraembryonic_tissu1.16615540
46MP0002111_abnormal_tail_morphology1.16407192
47MP0003755_abnormal_palate_morphology1.16295572
48MP0004197_abnormal_fetal_growth/weight/1.15674676
49MP0000467_abnormal_esophagus_morphology1.14383550
50MP0003172_abnormal_lysosome_physiology1.12142740
51MP0005075_abnormal_melanosome_morpholog1.08225165
52MP0002932_abnormal_joint_morphology1.07263118
53MP0003567_abnormal_fetal_cardiomyocyte1.05902099
54MP0000639_abnormal_adrenal_gland1.05547824
55MP0001697_abnormal_embryo_size1.05181469
56MP0005266_abnormal_metabolism1.00865195
57MP0002269_muscular_atrophy0.98132988
58MP0000490_abnormal_crypts_of0.97810331
59MP0000049_abnormal_middle_ear0.97526468
60MP0005058_abnormal_lysosome_morphology0.96806981
61MP0004957_abnormal_blastocyst_morpholog0.94537368
62MP0001672_abnormal_embryogenesis/_devel0.94537296
63MP0005380_embryogenesis_phenotype0.94537296
64MP0003935_abnormal_craniofacial_develop0.94084140
65MP0002116_abnormal_craniofacial_bone0.93909341
66MP0002060_abnormal_skin_morphology0.93648946
67MP0005248_abnormal_Harderian_gland0.86052276
68MP0008932_abnormal_embryonic_tissue0.85392195
69MP0009115_abnormal_fat_cell0.84210542
70MP0004134_abnormal_chest_morphology0.83713789
71MP0002114_abnormal_axial_skeleton0.83352981
72MP0003941_abnormal_skin_development0.81395388
73MP0005508_abnormal_skeleton_morphology0.81204788
74MP0003385_abnormal_body_wall0.80353177
75MP0003045_fibrosis0.79096654
76MP0000350_abnormal_cell_proliferation0.78845165
77MP0002332_abnormal_exercise_endurance0.78611673
78MP0002405_respiratory_system_inflammati0.78052296
79MP0003136_yellow_coat_color0.75736291
80MP0002075_abnormal_coat/hair_pigmentati0.75186036
81MP0005645_abnormal_hypothalamus_physiol0.75106830
82MP0001186_pigmentation_phenotype0.74463168
83MP0000432_abnormal_head_morphology0.74005637
84MP0001324_abnormal_eye_pigmentation0.72742674
85MP0003111_abnormal_nucleus_morphology0.70771461
86MP0000678_abnormal_parathyroid_gland0.70177762
87MP0005501_abnormal_skin_physiology0.69858644
88MP0002877_abnormal_melanocyte_morpholog0.69304814
89MP0005391_vision/eye_phenotype0.67084934
90MP0002019_abnormal_tumor_incidence0.66836196
91MP0005253_abnormal_eye_physiology0.66201906
92MP0003943_abnormal_hepatobiliary_system0.64691311
93MP0003984_embryonic_growth_retardation0.64434129
94MP0003566_abnormal_cell_adhesion0.64185622
95MP0003137_abnormal_impulse_conducting0.62014824
96MP0010630_abnormal_cardiac_muscle0.61927292
97MP0003936_abnormal_reproductive_system0.61616979
98MP0002132_abnormal_respiratory_system0.61236101
99MP0003942_abnormal_urinary_system0.61041034
100MP0000516_abnormal_urinary_system0.60145998

Predicted human phenotypes

RankGene SetZ-score
1Annular pancreas (HP:0001734)5.65364302
2Rib fusion (HP:0000902)5.58047082
3Concave nail (HP:0001598)5.15869481
4Rectal fistula (HP:0100590)5.01303569
5Rectovaginal fistula (HP:0000143)5.01303569
6Alopecia of scalp (HP:0002293)5.00048906
7Pustule (HP:0200039)4.98471331
8Vaginal fistula (HP:0004320)4.92149320
9Increased IgM level (HP:0003496)4.82497124
10Turricephaly (HP:0000262)4.74659122
11Facial hemangioma (HP:0000329)4.72211878
12Ulnar bowing (HP:0003031)4.66792668
13Intestinal fistula (HP:0100819)4.51602589
14Abnormal hemoglobin (HP:0011902)4.46162371
15Poikiloderma (HP:0001029)4.22901441
16Coronal craniosynostosis (HP:0004440)4.02810915
17Hypochromic microcytic anemia (HP:0004840)3.97520846
18Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.74989319
19Intestinal atresia (HP:0011100)3.70143787
20Abnormality of male internal genitalia (HP:0000022)3.64826100
21Tongue fasciculations (HP:0001308)3.57978182
22Male infertility (HP:0003251)3.56558496
23Short humerus (HP:0005792)3.53011143
24Aplasia/Hypoplasia of the vertebrae (HP:0008515)3.48609355
25Vertebral hypoplasia (HP:0008417)3.48609355
26Alacrima (HP:0000522)3.38508079
27Aplasia/hypoplasia of the humerus (HP:0006507)3.33522369
28Anteriorly placed anus (HP:0001545)3.29979111
29Orthostatic hypotension (HP:0001278)3.29827747
30Popliteal pterygium (HP:0009756)3.28393619
31Urinary glycosaminoglycan excretion (HP:0003541)3.27928680
32Mucopolysacchariduria (HP:0008155)3.27928680
33Muscle fibrillation (HP:0010546)3.26857856
34Dysautonomia (HP:0002459)3.17839026
35Congenital hip dislocation (HP:0001374)3.13881091
36Abnormality of the aortic arch (HP:0012303)3.12767949
37Hypotrichosis (HP:0001006)2.98173047
38Abnormality of mucopolysaccharide metabolism (HP:0011020)2.96579625
39Abnormality of polysaccharide metabolism (HP:0011012)2.96579625
40Abnormality of glycosaminoglycan metabolism (HP:0004371)2.96579625
41Absent radius (HP:0003974)2.95388445
42Choanal stenosis (HP:0000452)2.88576229
43Bifid uvula (HP:0000193)2.88305239
44Large for gestational age (HP:0001520)2.88256882
45Pancreatic islet-cell hyperplasia (HP:0004510)2.86938424
46Short chin (HP:0000331)2.86193762
47Growth hormone excess (HP:0000845)2.82027331
48Absent forearm bone (HP:0003953)2.78947106
49Aplasia involving forearm bones (HP:0009822)2.78947106
50Hamartoma (HP:0010566)2.78335966
51Redundant skin (HP:0001582)2.76645356
52Dysostosis multiplex (HP:0000943)2.76017558
53Broad alveolar ridges (HP:0000187)2.75044606
54Premature skin wrinkling (HP:0100678)2.74225461
55Absent thumb (HP:0009777)2.73183093
56Bowed forearm bones (HP:0003956)2.64367969
57Bowing of the arm (HP:0006488)2.64367969
58Albinism (HP:0001022)2.64305821
59Aplasia of the musculature (HP:0100854)2.63708591
60Squamous cell carcinoma (HP:0002860)2.62559682
61Diaphragmatic weakness (HP:0009113)2.62184702
62Hypoplasia of the ulna (HP:0003022)2.56701253
63Polycythemia (HP:0001901)2.55708444
64Clumsiness (HP:0002312)2.54053646
65Volvulus (HP:0002580)2.52139106
66Decreased lacrimation (HP:0000633)2.52070604
67Median cleft lip (HP:0000161)2.42693376
68Narrow nasal bridge (HP:0000446)2.41990725
69Joint stiffness (HP:0001387)2.40178340
70Hypotelorism (HP:0000601)2.39918631
71IgA deficiency (HP:0002720)2.37610639
72Hypokinesia (HP:0002375)2.34036572
73Amelogenesis imperfecta (HP:0000705)2.31676241
74Increased number of teeth (HP:0011069)2.29298996
75Lip pit (HP:0100267)2.28907029
76Premature graying of hair (HP:0002216)2.28522724
77Basal cell carcinoma (HP:0002671)2.27281913
78Capillary hemangiomas (HP:0005306)2.26943780
79Gastrointestinal atresia (HP:0002589)2.26726558
80Patellar aplasia (HP:0006443)2.20446976
81Selective tooth agenesis (HP:0001592)2.19978414
82Split hand (HP:0001171)2.17080028
83Bulbar palsy (HP:0001283)2.14815327
84Cerebral aneurysm (HP:0004944)2.14454488
85Vertebral fusion (HP:0002948)2.13169951
86Hypochromic anemia (HP:0001931)2.09783024
87Cheilitis (HP:0100825)2.09530157
88Abnormality of the labia minora (HP:0012880)2.08173580
89Aplasia/Hypoplasia of the patella (HP:0006498)2.07481663
90Hemivertebrae (HP:0002937)2.05791050
91Aplasia/Hypoplasia of the ulna (HP:0006495)2.02492158
92Lower limb hyperreflexia (HP:0002395)1.97869849
93Hypoplasia of the radius (HP:0002984)1.95694688
94Small hand (HP:0200055)1.94398637
95Progressive sensorineural hearing impairment (HP:0000408)1.90887128
96Bilateral sensorineural hearing impairment (HP:0008619)1.88196737
97Short 5th finger (HP:0009237)1.87635348
98Exertional dyspnea (HP:0002875)1.86966163
99Exocrine pancreatic insufficiency (HP:0001738)1.86934777
100Carpal synostosis (HP:0009702)1.85584442

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.21219268
2ICK5.78447112
3DDR25.22630185
4MAP3K65.06015558
5MAP3K113.41481253
6PINK13.34091153
7MATK2.98794357
8TYRO32.93320207
9FGR2.89813936
10UHMK12.38419610
11DAPK12.34792452
12BMX2.27286410
13PRKD22.19335570
14CSK2.13673634
15YES12.07465500
16PIM22.03170512
17DYRK1B1.96658071
18PDGFRA1.90610070
19TRPM71.78262621
20AKT31.54666715
21CDK71.45992822
22CDK61.36183023
23LATS21.34396413
24PIM11.31789760
25RPS6KC11.29955780
26RPS6KL11.29955780
27RPS6KA61.17112408
28CDC42BPA1.14638094
29GSK3A1.12635073
30PHKG21.10061246
31PHKG11.10061246
32TAOK21.07766664
33PRPF4B1.00350546
34MAPK110.90930956
35HIPK20.89597030
36CHEK20.87876500
37ERBB30.85903360
38RPS6KB20.82322905
39MAP3K30.72654461
40DYRK30.68399117
41MAP3K100.67300434
42EPHA20.65604399
43RPS6KA10.62890233
44MTOR0.61014910
45PRKAA10.57759000
46RIPK10.54281620
47PLK10.53599095
48CAMK2B0.50827564
49CAMK2G0.44055667
50TAOK10.43163067
51PDGFRB0.41832572
52ATR0.41153310
53CSNK1G10.40935605
54TNK20.40747380
55EGFR0.40035541
56MAPK30.34920275
57MAPK10.34633577
58CDK20.34558352
59CSNK2A10.34463964
60RPS6KB10.34140743
61CAMK2D0.33244922
62LYN0.30096624
63MAPK100.28853951
64STK30.28724048
65MAPK140.28417884
66PRKAA20.28059233
67DYRK20.27587634
68CAMK2A0.27370886
69MAPK40.27129119
70AURKA0.24730784
71STK380.24467969
72MAPKAPK20.24373253
73PRKCZ0.24208075
74INSR0.24048357
75RAF10.23233492
76SGK10.23218468
77TRIB30.23103754
78MAP3K90.22970882
79PTK20.22215034
80CSNK2A20.21759327
81MST40.20821694
82ATM0.20569344
83PRKD10.19987593
84MAPKAPK30.19284645
85LATS10.18299825
86CHUK0.18140900
87MAP2K20.17063250
88MARK20.15531851
89PRKCD0.15404899
90PRKCI0.15311194
91CDK10.15169910
92ZAK0.15008646
93CHEK10.13415857
94ALK0.13039495
95GSK3B0.12385719
96IKBKB0.12203438
97PAK20.11714785
98RPS6KA30.11292827
99ABL10.10274794
100AKT10.10031535

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000615.93761592
2Base excision repair_Homo sapiens_hsa034104.36741512
3Mismatch repair_Homo sapiens_hsa034304.20801455
4Pentose and glucuronate interconversions_Homo sapiens_hsa000403.94451557
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.89037824
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.83351267
7DNA replication_Homo sapiens_hsa030302.65921937
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.48211709
9Circadian rhythm_Homo sapiens_hsa047102.44666969
10Notch signaling pathway_Homo sapiens_hsa043302.22866693
11Sulfur relay system_Homo sapiens_hsa041222.22421115
12Hippo signaling pathway_Homo sapiens_hsa043902.12151860
13Arginine and proline metabolism_Homo sapiens_hsa003301.95934610
14Hedgehog signaling pathway_Homo sapiens_hsa043401.93176968
15Adherens junction_Homo sapiens_hsa045201.83698509
16mTOR signaling pathway_Homo sapiens_hsa041501.82937743
17mRNA surveillance pathway_Homo sapiens_hsa030151.67987030
18Nucleotide excision repair_Homo sapiens_hsa034201.61097245
19TGF-beta signaling pathway_Homo sapiens_hsa043501.48652442
20Fatty acid metabolism_Homo sapiens_hsa012121.41015413
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.40143902
22Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.37887836
23Longevity regulating pathway - mammal_Homo sapiens_hsa042111.36267456
24Transcriptional misregulation in cancer_Homo sapiens_hsa052021.35747902
25p53 signaling pathway_Homo sapiens_hsa041151.31589877
26Bladder cancer_Homo sapiens_hsa052191.30727052
27Wnt signaling pathway_Homo sapiens_hsa043101.28692690
28Basal cell carcinoma_Homo sapiens_hsa052171.28042656
29Glutathione metabolism_Homo sapiens_hsa004801.27354061
30Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.26001320
31Biosynthesis of amino acids_Homo sapiens_hsa012301.23872301
32Fanconi anemia pathway_Homo sapiens_hsa034601.23738134
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23476036
34Spliceosome_Homo sapiens_hsa030401.22736068
35Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.21906268
36Chemical carcinogenesis_Homo sapiens_hsa052041.19156978
37Starch and sucrose metabolism_Homo sapiens_hsa005001.15960056
38RNA transport_Homo sapiens_hsa030131.13170936
39Shigellosis_Homo sapiens_hsa051311.10484551
40Folate biosynthesis_Homo sapiens_hsa007901.08842009
41Homologous recombination_Homo sapiens_hsa034401.04331469
42Drug metabolism - other enzymes_Homo sapiens_hsa009831.03348954
43Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.97307985
44Glycosaminoglycan degradation_Homo sapiens_hsa005310.95999153
45VEGF signaling pathway_Homo sapiens_hsa043700.94380924
46Maturity onset diabetes of the young_Homo sapiens_hsa049500.91304686
47Tight junction_Homo sapiens_hsa045300.90892353
48Galactose metabolism_Homo sapiens_hsa000520.90683568
49Lysine degradation_Homo sapiens_hsa003100.89759536
50Fructose and mannose metabolism_Homo sapiens_hsa000510.83842830
51Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.78371953
52Cell cycle_Homo sapiens_hsa041100.76445427
53Colorectal cancer_Homo sapiens_hsa052100.76314895
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.71591797
55Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70166157
56MicroRNAs in cancer_Homo sapiens_hsa052060.65983014
57Mineral absorption_Homo sapiens_hsa049780.62796354
58Arginine biosynthesis_Homo sapiens_hsa002200.62633943
59Choline metabolism in cancer_Homo sapiens_hsa052310.59137122
60ErbB signaling pathway_Homo sapiens_hsa040120.58681240
61Retinol metabolism_Homo sapiens_hsa008300.57431201
62Oocyte meiosis_Homo sapiens_hsa041140.55102922
63Dorso-ventral axis formation_Homo sapiens_hsa043200.52911794
64Gap junction_Homo sapiens_hsa045400.51573522
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.49265565
66Chronic myeloid leukemia_Homo sapiens_hsa052200.44582459
67Primary immunodeficiency_Homo sapiens_hsa053400.44368395
68MAPK signaling pathway_Homo sapiens_hsa040100.44333117
69Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.43922572
70Acute myeloid leukemia_Homo sapiens_hsa052210.42740179
71Small cell lung cancer_Homo sapiens_hsa052220.38713276
72Viral myocarditis_Homo sapiens_hsa054160.38657032
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37194897
74Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37082051
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37009897
76Thyroid cancer_Homo sapiens_hsa052160.36956379
77AMPK signaling pathway_Homo sapiens_hsa041520.36778647
78Sulfur metabolism_Homo sapiens_hsa009200.35474374
79Insulin signaling pathway_Homo sapiens_hsa049100.34722466
80Legionellosis_Homo sapiens_hsa051340.34656819
81Proteoglycans in cancer_Homo sapiens_hsa052050.33709952
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27832840
83Prostate cancer_Homo sapiens_hsa052150.25848798
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25693048
85Steroid biosynthesis_Homo sapiens_hsa001000.22960813
86PI3K-Akt signaling pathway_Homo sapiens_hsa041510.22760007
87Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.22692147
88Endometrial cancer_Homo sapiens_hsa052130.21787100
89Viral carcinogenesis_Homo sapiens_hsa052030.19974857
90Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.19512327
91Melanoma_Homo sapiens_hsa052180.18602508
92Focal adhesion_Homo sapiens_hsa045100.18561068
93Pathways in cancer_Homo sapiens_hsa052000.17847095
94Central carbon metabolism in cancer_Homo sapiens_hsa052300.14480501
95HTLV-I infection_Homo sapiens_hsa051660.13525414
96Rap1 signaling pathway_Homo sapiens_hsa040150.12097617
97Prion diseases_Homo sapiens_hsa050200.11319668
98Fatty acid elongation_Homo sapiens_hsa000620.10685878
99Estrogen signaling pathway_Homo sapiens_hsa049150.09137269
100Prolactin signaling pathway_Homo sapiens_hsa049170.06245173

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »