

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proline metabolic process (GO:0006560) | 8.75962277 |
| 2 | transcription from mitochondrial promoter (GO:0006390) | 8.46113375 |
| 3 | embryonic process involved in female pregnancy (GO:0060136) | 8.02932952 |
| 4 | replication fork processing (GO:0031297) | 7.72942295 |
| 5 | positive regulation of protein homooligomerization (GO:0032464) | 7.53303254 |
| 6 | establishment of apical/basal cell polarity (GO:0035089) | 6.92931569 |
| 7 | oxidative demethylation (GO:0070989) | 6.73558278 |
| 8 | regulation of integrin activation (GO:0033623) | 6.63506746 |
| 9 | regulation of protein homooligomerization (GO:0032462) | 6.42647525 |
| 10 | DNA deamination (GO:0045006) | 6.41818064 |
| 11 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 6.09597308 |
| 12 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 6.07722337 |
| 13 | establishment of monopolar cell polarity (GO:0061162) | 6.07722337 |
| 14 | DNA strand renaturation (GO:0000733) | 5.61907001 |
| 15 | poly(A)+ mRNA export from nucleus (GO:0016973) | 5.56562119 |
| 16 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 5.25534110 |
| 17 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 5.25534110 |
| 18 | negative regulation of JAK-STAT cascade (GO:0046426) | 5.13184673 |
| 19 | mitochondrial DNA metabolic process (GO:0032042) | 5.11242325 |
| 20 | embryonic placenta development (GO:0001892) | 4.91759430 |
| 21 | cellular response to ATP (GO:0071318) | 4.87700428 |
| 22 | viral mRNA export from host cell nucleus (GO:0046784) | 4.69469789 |
| 23 | negative regulation of Ras GTPase activity (GO:0034261) | 4.61298446 |
| 24 | mitotic G1 DNA damage checkpoint (GO:0031571) | 4.61063411 |
| 25 | glutamine family amino acid biosynthetic process (GO:0009084) | 4.60505098 |
| 26 | negative regulation of cell cycle arrest (GO:0071157) | 4.57985976 |
| 27 | mRNA cleavage (GO:0006379) | 4.53362868 |
| 28 | cellular response to zinc ion (GO:0071294) | 4.52370394 |
| 29 | negative regulation of protein oligomerization (GO:0032460) | 4.33347303 |
| 30 | glial cell migration (GO:0008347) | 4.30622330 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.22279895 |
| 32 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 4.19328282 |
| 33 | positive regulation of developmental pigmentation (GO:0048087) | 4.12098625 |
| 34 | DNA integration (GO:0015074) | 4.10278555 |
| 35 | G1 DNA damage checkpoint (GO:0044783) | 4.09113666 |
| 36 | positive regulation of protein oligomerization (GO:0032461) | 4.08255663 |
| 37 | face development (GO:0060324) | 4.07841494 |
| 38 | mitotic G1/S transition checkpoint (GO:0044819) | 4.05244566 |
| 39 | regulation of translational fidelity (GO:0006450) | 4.02605673 |
| 40 | convergent extension (GO:0060026) | 3.95902919 |
| 41 | regulation of protein oligomerization (GO:0032459) | 3.93815361 |
| 42 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.91463149 |
| 43 | DNA double-strand break processing (GO:0000729) | 3.90228010 |
| 44 | base-excision repair, AP site formation (GO:0006285) | 3.88715355 |
| 45 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.88113176 |
| 46 | embryonic camera-type eye development (GO:0031076) | 3.87337984 |
| 47 | auditory receptor cell stereocilium organization (GO:0060088) | 3.87077131 |
| 48 | base-excision repair (GO:0006284) | 3.83614659 |
| 49 | sulfur amino acid catabolic process (GO:0000098) | 3.80994987 |
| 50 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.80759626 |
| 51 | positive regulation by host of viral transcription (GO:0043923) | 3.76761861 |
| 52 | negative regulation of heart rate (GO:0010459) | 3.75367753 |
| 53 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.73726733 |
| 54 | non-recombinational repair (GO:0000726) | 3.66032124 |
| 55 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.66032124 |
| 56 | positive regulation of DNA repair (GO:0045739) | 3.65111998 |
| 57 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.62622301 |
| 58 | positive regulation of receptor recycling (GO:0001921) | 3.60154549 |
| 59 | L-ascorbic acid metabolic process (GO:0019852) | 3.53709930 |
| 60 | signal complex assembly (GO:0007172) | 3.52874349 |
| 61 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 3.52733065 |
| 62 | formation of translation preinitiation complex (GO:0001731) | 3.51945005 |
| 63 | alkaloid metabolic process (GO:0009820) | 3.49992573 |
| 64 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.46696046 |
| 65 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.46696046 |
| 66 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.46696046 |
| 67 | anatomical structure regression (GO:0060033) | 3.44921973 |
| 68 | trophectodermal cell differentiation (GO:0001829) | 3.44800232 |
| 69 | regulation of RNA export from nucleus (GO:0046831) | 3.39265989 |
| 70 | histone H4-K12 acetylation (GO:0043983) | 3.38568596 |
| 71 | DNA ligation (GO:0006266) | 3.38324631 |
| 72 | labyrinthine layer development (GO:0060711) | 3.36272075 |
| 73 | negative regulation of cartilage development (GO:0061037) | 3.35524116 |
| 74 | regulation of mitochondrial depolarization (GO:0051900) | 3.35442725 |
| 75 | dosage compensation (GO:0007549) | 3.33105291 |
| 76 | apoptotic process involved in morphogenesis (GO:0060561) | 3.32883156 |
| 77 | DNA topological change (GO:0006265) | 3.30705954 |
| 78 | mitotic cell cycle arrest (GO:0071850) | 3.28798144 |
| 79 | negative regulation of mRNA processing (GO:0050686) | 3.27829995 |
| 80 | mitochondrial RNA metabolic process (GO:0000959) | 3.27821895 |
| 81 | regulation of sister chromatid cohesion (GO:0007063) | 3.25676598 |
| 82 | protein targeting to lysosome (GO:0006622) | 3.23961520 |
| 83 | establishment of protein localization to vacuole (GO:0072666) | 3.23961520 |
| 84 | protein targeting to vacuole (GO:0006623) | 3.23961520 |
| 85 | activation of Rac GTPase activity (GO:0032863) | 3.23767149 |
| 86 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.19854327 |
| 87 | regulation of podosome assembly (GO:0071801) | 3.19502517 |
| 88 | negative regulation of appetite (GO:0032099) | 3.18834472 |
| 89 | negative regulation of response to food (GO:0032096) | 3.18834472 |
| 90 | GDP-mannose metabolic process (GO:0019673) | 3.15832930 |
| 91 | termination of RNA polymerase II transcription (GO:0006369) | 3.14346543 |
| 92 | embryonic eye morphogenesis (GO:0048048) | 3.13914649 |
| 93 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.13141091 |
| 94 | hypotonic response (GO:0006971) | 3.12197410 |
| 95 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.10577840 |
| 96 | mRNA polyadenylation (GO:0006378) | 3.05824887 |
| 97 | membrane invagination (GO:0010324) | 3.05399195 |
| 98 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.04870355 |
| 99 | meiotic chromosome segregation (GO:0045132) | 3.04296318 |
| 100 | proline biosynthetic process (GO:0006561) | 11.5421372 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 3.85481000 |
| 2 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 3.75119511 |
| 3 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 3.75119511 |
| 4 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 3.75119511 |
| 5 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 3.61548872 |
| 6 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.42740237 |
| 7 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 3.13174224 |
| 8 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 3.02594042 |
| 9 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.82730355 |
| 10 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 2.65774238 |
| 11 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.63353034 |
| 12 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 2.49464225 |
| 13 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.47649034 |
| 14 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 2.34425978 |
| 15 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.30423275 |
| 16 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 2.30059248 |
| 17 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 2.18853708 |
| 18 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 2.17702766 |
| 19 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 2.15724459 |
| 20 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 2.08862191 |
| 21 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.08841510 |
| 22 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 2.06504021 |
| 23 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.94717772 |
| 24 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.85131670 |
| 25 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.82271030 |
| 26 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.82094161 |
| 27 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.81198304 |
| 28 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.80802075 |
| 29 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.80612689 |
| 30 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.79851063 |
| 31 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.73701507 |
| 32 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.67731006 |
| 33 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.67548804 |
| 34 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.67071810 |
| 35 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.67048320 |
| 36 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.60071798 |
| 37 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.56800441 |
| 38 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.53196252 |
| 39 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.52655932 |
| 40 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.50732851 |
| 41 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.48938569 |
| 42 | POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 1.47893059 |
| 43 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.45332205 |
| 44 | NANOG_18692474_ChIP-Seq_MESCs_Mouse | 1.44627308 |
| 45 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.41490319 |
| 46 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.40093765 |
| 47 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.37657212 |
| 48 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.36029424 |
| 49 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.35799881 |
| 50 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.34484737 |
| 51 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.33466975 |
| 52 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.29992302 |
| 53 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.29734726 |
| 54 | * PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 1.28573057 |
| 55 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.28049736 |
| 56 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 1.25525043 |
| 57 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 1.24881928 |
| 58 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.24826959 |
| 59 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.24690017 |
| 60 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.24038406 |
| 61 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.23305398 |
| 62 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 1.21453338 |
| 63 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.20969288 |
| 64 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.20773113 |
| 65 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.20035866 |
| 66 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.17310347 |
| 67 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.16891306 |
| 68 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.15542475 |
| 69 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.15077992 |
| 70 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 1.14007412 |
| 71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13819801 |
| 72 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.12415517 |
| 73 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.10948011 |
| 74 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.10183328 |
| 75 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.09884821 |
| 76 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.09296981 |
| 77 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 1.09129003 |
| 78 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.09085401 |
| 79 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.08229968 |
| 80 | KDM2B_26808549_Chip-Seq_K562_Human | 1.08192804 |
| 81 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.07926692 |
| 82 | MYC_22102868_ChIP-Seq_BL_Human | 1.07280820 |
| 83 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.07206139 |
| 84 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.06934234 |
| 85 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.06747964 |
| 86 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.06623940 |
| 87 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.06083410 |
| 88 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.05743955 |
| 89 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.04632021 |
| 90 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.03289650 |
| 91 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.02347263 |
| 92 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.01830437 |
| 93 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.01318473 |
| 94 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.99999143 |
| 95 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.98853242 |
| 96 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.97598984 |
| 97 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.95557229 |
| 98 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.94764179 |
| 99 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.92993043 |
| 100 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92672360 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 5.82954873 |
| 2 | MP0005171_absent_coat_pigmentation | 5.11601391 |
| 3 | MP0010030_abnormal_orbit_morphology | 4.86333559 |
| 4 | MP0009278_abnormal_bone_marrow | 4.65652660 |
| 5 | MP0002009_preneoplasia | 3.87293494 |
| 6 | MP0004233_abnormal_muscle_weight | 3.64242949 |
| 7 | MP0008995_early_reproductive_senescence | 2.70581197 |
| 8 | MP0003890_abnormal_embryonic-extraembry | 2.58177922 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.44302926 |
| 10 | MP0002249_abnormal_larynx_morphology | 2.39628858 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.33049443 |
| 12 | MP0001545_abnormal_hematopoietic_system | 2.12472958 |
| 13 | MP0005397_hematopoietic_system_phenotyp | 2.12472958 |
| 14 | MP0003786_premature_aging | 2.07524109 |
| 15 | MP0003453_abnormal_keratinocyte_physiol | 2.06076391 |
| 16 | MP0003283_abnormal_digestive_organ | 2.02756482 |
| 17 | MP0004133_heterotaxia | 1.99328205 |
| 18 | MP0000579_abnormal_nail_morphology | 1.90866385 |
| 19 | MP0005174_abnormal_tail_pigmentation | 1.87685672 |
| 20 | MP0003119_abnormal_digestive_system | 1.81542846 |
| 21 | MP0005499_abnormal_olfactory_system | 1.79374426 |
| 22 | MP0005394_taste/olfaction_phenotype | 1.79374426 |
| 23 | MP0002282_abnormal_trachea_morphology | 1.76791424 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.72101723 |
| 25 | MP0000762_abnormal_tongue_morphology | 1.60224518 |
| 26 | MP0010094_abnormal_chromosome_stability | 1.58382865 |
| 27 | MP0005076_abnormal_cell_differentiation | 1.57523464 |
| 28 | MP0009053_abnormal_anal_canal | 1.51381264 |
| 29 | MP0001293_anophthalmia | 1.47100388 |
| 30 | MP0005085_abnormal_gallbladder_physiolo | 1.46275095 |
| 31 | MP0010352_gastrointestinal_tract_polyps | 1.38682472 |
| 32 | MP0000015_abnormal_ear_pigmentation | 1.37870977 |
| 33 | MP0003828_pulmonary_edema | 1.33538369 |
| 34 | MP0002086_abnormal_extraembryonic_tissu | 1.33442844 |
| 35 | MP0000462_abnormal_digestive_system | 1.31998087 |
| 36 | MP0002084_abnormal_developmental_patter | 1.30712698 |
| 37 | MP0001340_abnormal_eyelid_morphology | 1.27974693 |
| 38 | MP0000470_abnormal_stomach_morphology | 1.27742706 |
| 39 | MP0008058_abnormal_DNA_repair | 1.26824042 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.24108400 |
| 41 | MP0000371_diluted_coat_color | 1.23604304 |
| 42 | MP0005365_abnormal_bile_salt | 1.23548715 |
| 43 | MP0002796_impaired_skin_barrier | 1.22279749 |
| 44 | MP0002085_abnormal_embryonic_tissue | 1.19286906 |
| 45 | MP0004264_abnormal_extraembryonic_tissu | 1.16615540 |
| 46 | MP0002111_abnormal_tail_morphology | 1.16407192 |
| 47 | MP0003755_abnormal_palate_morphology | 1.16295572 |
| 48 | MP0004197_abnormal_fetal_growth/weight/ | 1.15674676 |
| 49 | MP0000467_abnormal_esophagus_morphology | 1.14383550 |
| 50 | MP0003172_abnormal_lysosome_physiology | 1.12142740 |
| 51 | MP0005075_abnormal_melanosome_morpholog | 1.08225165 |
| 52 | MP0002932_abnormal_joint_morphology | 1.07263118 |
| 53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.05902099 |
| 54 | MP0000639_abnormal_adrenal_gland | 1.05547824 |
| 55 | MP0001697_abnormal_embryo_size | 1.05181469 |
| 56 | MP0005266_abnormal_metabolism | 1.00865195 |
| 57 | MP0002269_muscular_atrophy | 0.98132988 |
| 58 | MP0000490_abnormal_crypts_of | 0.97810331 |
| 59 | MP0000049_abnormal_middle_ear | 0.97526468 |
| 60 | MP0005058_abnormal_lysosome_morphology | 0.96806981 |
| 61 | MP0004957_abnormal_blastocyst_morpholog | 0.94537368 |
| 62 | MP0001672_abnormal_embryogenesis/_devel | 0.94537296 |
| 63 | MP0005380_embryogenesis_phenotype | 0.94537296 |
| 64 | MP0003935_abnormal_craniofacial_develop | 0.94084140 |
| 65 | MP0002116_abnormal_craniofacial_bone | 0.93909341 |
| 66 | MP0002060_abnormal_skin_morphology | 0.93648946 |
| 67 | MP0005248_abnormal_Harderian_gland | 0.86052276 |
| 68 | MP0008932_abnormal_embryonic_tissue | 0.85392195 |
| 69 | MP0009115_abnormal_fat_cell | 0.84210542 |
| 70 | MP0004134_abnormal_chest_morphology | 0.83713789 |
| 71 | MP0002114_abnormal_axial_skeleton | 0.83352981 |
| 72 | MP0003941_abnormal_skin_development | 0.81395388 |
| 73 | MP0005508_abnormal_skeleton_morphology | 0.81204788 |
| 74 | MP0003385_abnormal_body_wall | 0.80353177 |
| 75 | MP0003045_fibrosis | 0.79096654 |
| 76 | MP0000350_abnormal_cell_proliferation | 0.78845165 |
| 77 | MP0002332_abnormal_exercise_endurance | 0.78611673 |
| 78 | MP0002405_respiratory_system_inflammati | 0.78052296 |
| 79 | MP0003136_yellow_coat_color | 0.75736291 |
| 80 | MP0002075_abnormal_coat/hair_pigmentati | 0.75186036 |
| 81 | MP0005645_abnormal_hypothalamus_physiol | 0.75106830 |
| 82 | MP0001186_pigmentation_phenotype | 0.74463168 |
| 83 | MP0000432_abnormal_head_morphology | 0.74005637 |
| 84 | MP0001324_abnormal_eye_pigmentation | 0.72742674 |
| 85 | MP0003111_abnormal_nucleus_morphology | 0.70771461 |
| 86 | MP0000678_abnormal_parathyroid_gland | 0.70177762 |
| 87 | MP0005501_abnormal_skin_physiology | 0.69858644 |
| 88 | MP0002877_abnormal_melanocyte_morpholog | 0.69304814 |
| 89 | MP0005391_vision/eye_phenotype | 0.67084934 |
| 90 | MP0002019_abnormal_tumor_incidence | 0.66836196 |
| 91 | MP0005253_abnormal_eye_physiology | 0.66201906 |
| 92 | MP0003943_abnormal_hepatobiliary_system | 0.64691311 |
| 93 | MP0003984_embryonic_growth_retardation | 0.64434129 |
| 94 | MP0003566_abnormal_cell_adhesion | 0.64185622 |
| 95 | MP0003137_abnormal_impulse_conducting | 0.62014824 |
| 96 | MP0010630_abnormal_cardiac_muscle | 0.61927292 |
| 97 | MP0003936_abnormal_reproductive_system | 0.61616979 |
| 98 | MP0002132_abnormal_respiratory_system | 0.61236101 |
| 99 | MP0003942_abnormal_urinary_system | 0.61041034 |
| 100 | MP0000516_abnormal_urinary_system | 0.60145998 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Annular pancreas (HP:0001734) | 5.65364302 |
| 2 | Rib fusion (HP:0000902) | 5.58047082 |
| 3 | Concave nail (HP:0001598) | 5.15869481 |
| 4 | Rectal fistula (HP:0100590) | 5.01303569 |
| 5 | Rectovaginal fistula (HP:0000143) | 5.01303569 |
| 6 | Alopecia of scalp (HP:0002293) | 5.00048906 |
| 7 | Pustule (HP:0200039) | 4.98471331 |
| 8 | Vaginal fistula (HP:0004320) | 4.92149320 |
| 9 | Increased IgM level (HP:0003496) | 4.82497124 |
| 10 | Turricephaly (HP:0000262) | 4.74659122 |
| 11 | Facial hemangioma (HP:0000329) | 4.72211878 |
| 12 | Ulnar bowing (HP:0003031) | 4.66792668 |
| 13 | Intestinal fistula (HP:0100819) | 4.51602589 |
| 14 | Abnormal hemoglobin (HP:0011902) | 4.46162371 |
| 15 | Poikiloderma (HP:0001029) | 4.22901441 |
| 16 | Coronal craniosynostosis (HP:0004440) | 4.02810915 |
| 17 | Hypochromic microcytic anemia (HP:0004840) | 3.97520846 |
| 18 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.74989319 |
| 19 | Intestinal atresia (HP:0011100) | 3.70143787 |
| 20 | Abnormality of male internal genitalia (HP:0000022) | 3.64826100 |
| 21 | Tongue fasciculations (HP:0001308) | 3.57978182 |
| 22 | Male infertility (HP:0003251) | 3.56558496 |
| 23 | Short humerus (HP:0005792) | 3.53011143 |
| 24 | Vertebral hypoplasia (HP:0008417) | 3.48609355 |
| 25 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 3.48609355 |
| 26 | Alacrima (HP:0000522) | 3.38508079 |
| 27 | Aplasia/hypoplasia of the humerus (HP:0006507) | 3.33522369 |
| 28 | Anteriorly placed anus (HP:0001545) | 3.29979111 |
| 29 | Orthostatic hypotension (HP:0001278) | 3.29827747 |
| 30 | Popliteal pterygium (HP:0009756) | 3.28393619 |
| 31 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.27928680 |
| 32 | Mucopolysacchariduria (HP:0008155) | 3.27928680 |
| 33 | Muscle fibrillation (HP:0010546) | 3.26857856 |
| 34 | Dysautonomia (HP:0002459) | 3.17839026 |
| 35 | Congenital hip dislocation (HP:0001374) | 3.13881091 |
| 36 | Abnormality of the aortic arch (HP:0012303) | 3.12767949 |
| 37 | Hypotrichosis (HP:0001006) | 2.98173047 |
| 38 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.96579625 |
| 39 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.96579625 |
| 40 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.96579625 |
| 41 | Absent radius (HP:0003974) | 2.95388445 |
| 42 | Choanal stenosis (HP:0000452) | 2.88576229 |
| 43 | Bifid uvula (HP:0000193) | 2.88305239 |
| 44 | Large for gestational age (HP:0001520) | 2.88256882 |
| 45 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.86938424 |
| 46 | Short chin (HP:0000331) | 2.86193762 |
| 47 | Growth hormone excess (HP:0000845) | 2.82027331 |
| 48 | Absent forearm bone (HP:0003953) | 2.78947106 |
| 49 | Aplasia involving forearm bones (HP:0009822) | 2.78947106 |
| 50 | Hamartoma (HP:0010566) | 2.78335966 |
| 51 | Redundant skin (HP:0001582) | 2.76645356 |
| 52 | Dysostosis multiplex (HP:0000943) | 2.76017558 |
| 53 | Broad alveolar ridges (HP:0000187) | 2.75044606 |
| 54 | Premature skin wrinkling (HP:0100678) | 2.74225461 |
| 55 | Absent thumb (HP:0009777) | 2.73183093 |
| 56 | Bowing of the arm (HP:0006488) | 2.64367969 |
| 57 | Bowed forearm bones (HP:0003956) | 2.64367969 |
| 58 | Albinism (HP:0001022) | 2.64305821 |
| 59 | Aplasia of the musculature (HP:0100854) | 2.63708591 |
| 60 | Squamous cell carcinoma (HP:0002860) | 2.62559682 |
| 61 | Diaphragmatic weakness (HP:0009113) | 2.62184702 |
| 62 | Hypoplasia of the ulna (HP:0003022) | 2.56701253 |
| 63 | Polycythemia (HP:0001901) | 2.55708444 |
| 64 | Clumsiness (HP:0002312) | 2.54053646 |
| 65 | Volvulus (HP:0002580) | 2.52139106 |
| 66 | Decreased lacrimation (HP:0000633) | 2.52070604 |
| 67 | Median cleft lip (HP:0000161) | 2.42693376 |
| 68 | Narrow nasal bridge (HP:0000446) | 2.41990725 |
| 69 | Joint stiffness (HP:0001387) | 2.40178340 |
| 70 | Hypotelorism (HP:0000601) | 2.39918631 |
| 71 | IgA deficiency (HP:0002720) | 2.37610639 |
| 72 | Hypokinesia (HP:0002375) | 2.34036572 |
| 73 | Amelogenesis imperfecta (HP:0000705) | 2.31676241 |
| 74 | Increased number of teeth (HP:0011069) | 2.29298996 |
| 75 | Lip pit (HP:0100267) | 2.28907029 |
| 76 | Premature graying of hair (HP:0002216) | 2.28522724 |
| 77 | Basal cell carcinoma (HP:0002671) | 2.27281913 |
| 78 | Capillary hemangiomas (HP:0005306) | 2.26943780 |
| 79 | Gastrointestinal atresia (HP:0002589) | 2.26726558 |
| 80 | Patellar aplasia (HP:0006443) | 2.20446976 |
| 81 | Selective tooth agenesis (HP:0001592) | 2.19978414 |
| 82 | Split hand (HP:0001171) | 2.17080028 |
| 83 | Bulbar palsy (HP:0001283) | 2.14815327 |
| 84 | Cerebral aneurysm (HP:0004944) | 2.14454488 |
| 85 | Vertebral fusion (HP:0002948) | 2.13169951 |
| 86 | Hypochromic anemia (HP:0001931) | 2.09783024 |
| 87 | Cheilitis (HP:0100825) | 2.09530157 |
| 88 | Abnormality of the labia minora (HP:0012880) | 2.08173580 |
| 89 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.07481663 |
| 90 | Hemivertebrae (HP:0002937) | 2.05791050 |
| 91 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.02492158 |
| 92 | Lower limb hyperreflexia (HP:0002395) | 1.97869849 |
| 93 | Hypoplasia of the radius (HP:0002984) | 1.95694688 |
| 94 | Small hand (HP:0200055) | 1.94398637 |
| 95 | Progressive sensorineural hearing impairment (HP:0000408) | 1.90887128 |
| 96 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.88196737 |
| 97 | Short 5th finger (HP:0009237) | 1.87635348 |
| 98 | Exertional dyspnea (HP:0002875) | 1.86966163 |
| 99 | Exocrine pancreatic insufficiency (HP:0001738) | 1.86934777 |
| 100 | Carpal synostosis (HP:0009702) | 1.85584442 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAPK15 | 6.21219268 |
| 2 | ICK | 5.78447112 |
| 3 | DDR2 | 5.22630185 |
| 4 | MAP3K6 | 5.06015558 |
| 5 | MAP3K11 | 3.41481253 |
| 6 | PINK1 | 3.34091153 |
| 7 | MATK | 2.98794357 |
| 8 | TYRO3 | 2.93320207 |
| 9 | FGR | 2.89813936 |
| 10 | UHMK1 | 2.38419610 |
| 11 | DAPK1 | 2.34792452 |
| 12 | BMX | 2.27286410 |
| 13 | PRKD2 | 2.19335570 |
| 14 | CSK | 2.13673634 |
| 15 | YES1 | 2.07465500 |
| 16 | PIM2 | 2.03170512 |
| 17 | DYRK1B | 1.96658071 |
| 18 | PDGFRA | 1.90610070 |
| 19 | TRPM7 | 1.78262621 |
| 20 | AKT3 | 1.54666715 |
| 21 | CDK7 | 1.45992822 |
| 22 | CDK6 | 1.36183023 |
| 23 | LATS2 | 1.34396413 |
| 24 | PIM1 | 1.31789760 |
| 25 | RPS6KC1 | 1.29955780 |
| 26 | RPS6KL1 | 1.29955780 |
| 27 | RPS6KA6 | 1.17112408 |
| 28 | CDC42BPA | 1.14638094 |
| 29 | GSK3A | 1.12635073 |
| 30 | PHKG1 | 1.10061246 |
| 31 | PHKG2 | 1.10061246 |
| 32 | TAOK2 | 1.07766664 |
| 33 | PRPF4B | 1.00350546 |
| 34 | MAPK11 | 0.90930956 |
| 35 | HIPK2 | 0.89597030 |
| 36 | CHEK2 | 0.87876500 |
| 37 | ERBB3 | 0.85903360 |
| 38 | RPS6KB2 | 0.82322905 |
| 39 | MAP3K3 | 0.72654461 |
| 40 | DYRK3 | 0.68399117 |
| 41 | MAP3K10 | 0.67300434 |
| 42 | EPHA2 | 0.65604399 |
| 43 | RPS6KA1 | 0.62890233 |
| 44 | MTOR | 0.61014910 |
| 45 | PRKAA1 | 0.57759000 |
| 46 | RIPK1 | 0.54281620 |
| 47 | PLK1 | 0.53599095 |
| 48 | CAMK2B | 0.50827564 |
| 49 | CAMK2G | 0.44055667 |
| 50 | TAOK1 | 0.43163067 |
| 51 | PDGFRB | 0.41832572 |
| 52 | ATR | 0.41153310 |
| 53 | CSNK1G1 | 0.40935605 |
| 54 | TNK2 | 0.40747380 |
| 55 | EGFR | 0.40035541 |
| 56 | MAPK3 | 0.34920275 |
| 57 | MAPK1 | 0.34633577 |
| 58 | CDK2 | 0.34558352 |
| 59 | CSNK2A1 | 0.34463964 |
| 60 | RPS6KB1 | 0.34140743 |
| 61 | CAMK2D | 0.33244922 |
| 62 | LYN | 0.30096624 |
| 63 | MAPK10 | 0.28853951 |
| 64 | STK3 | 0.28724048 |
| 65 | MAPK14 | 0.28417884 |
| 66 | PRKAA2 | 0.28059233 |
| 67 | DYRK2 | 0.27587634 |
| 68 | CAMK2A | 0.27370886 |
| 69 | MAPK4 | 0.27129119 |
| 70 | AURKA | 0.24730784 |
| 71 | STK38 | 0.24467969 |
| 72 | MAPKAPK2 | 0.24373253 |
| 73 | PRKCZ | 0.24208075 |
| 74 | INSR | 0.24048357 |
| 75 | RAF1 | 0.23233492 |
| 76 | SGK1 | 0.23218468 |
| 77 | TRIB3 | 0.23103754 |
| 78 | MAP3K9 | 0.22970882 |
| 79 | PTK2 | 0.22215034 |
| 80 | CSNK2A2 | 0.21759327 |
| 81 | MST4 | 0.20821694 |
| 82 | ATM | 0.20569344 |
| 83 | PRKD1 | 0.19987593 |
| 84 | MAPKAPK3 | 0.19284645 |
| 85 | LATS1 | 0.18299825 |
| 86 | CHUK | 0.18140900 |
| 87 | MAP2K2 | 0.17063250 |
| 88 | MARK2 | 0.15531851 |
| 89 | PRKCD | 0.15404899 |
| 90 | PRKCI | 0.15311194 |
| 91 | CDK1 | 0.15169910 |
| 92 | ZAK | 0.15008646 |
| 93 | CHEK1 | 0.13415857 |
| 94 | ALK | 0.13039495 |
| 95 | GSK3B | 0.12385719 |
| 96 | IKBKB | 0.12203438 |
| 97 | PAK2 | 0.11714785 |
| 98 | RPS6KA3 | 0.11292827 |
| 99 | ABL1 | 0.10274794 |
| 100 | AKT1 | 0.10031535 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 5.93761592 |
| 2 | Base excision repair_Homo sapiens_hsa03410 | 4.36741512 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 4.20801455 |
| 4 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 3.94451557 |
| 5 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.89037824 |
| 6 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.83351267 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.65921937 |
| 8 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.48211709 |
| 9 | Circadian rhythm_Homo sapiens_hsa04710 | 2.44666969 |
| 10 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.22866693 |
| 11 | Sulfur relay system_Homo sapiens_hsa04122 | 2.22421115 |
| 12 | Hippo signaling pathway_Homo sapiens_hsa04390 | 2.12151860 |
| 13 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.95934610 |
| 14 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.93176968 |
| 15 | Adherens junction_Homo sapiens_hsa04520 | 1.83698509 |
| 16 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.82937743 |
| 17 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.67987030 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.61097245 |
| 19 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.48652442 |
| 20 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.41015413 |
| 21 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.40143902 |
| 22 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.37887836 |
| 23 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.36267456 |
| 24 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.35747902 |
| 25 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.31589877 |
| 26 | Bladder cancer_Homo sapiens_hsa05219 | 1.30727052 |
| 27 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.28692690 |
| 28 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.28042656 |
| 29 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.27354061 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.26001320 |
| 31 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.23872301 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.23738134 |
| 33 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.23476036 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 1.22736068 |
| 35 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.21906268 |
| 36 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.19156978 |
| 37 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.15960056 |
| 38 | RNA transport_Homo sapiens_hsa03013 | 1.13170936 |
| 39 | Shigellosis_Homo sapiens_hsa05131 | 1.10484551 |
| 40 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.08842009 |
| 41 | Homologous recombination_Homo sapiens_hsa03440 | 1.04331469 |
| 42 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.03348954 |
| 43 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.97307985 |
| 44 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.95999153 |
| 45 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.94380924 |
| 46 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.91304686 |
| 47 | Tight junction_Homo sapiens_hsa04530 | 0.90892353 |
| 48 | Galactose metabolism_Homo sapiens_hsa00052 | 0.90683568 |
| 49 | Lysine degradation_Homo sapiens_hsa00310 | 0.89759536 |
| 50 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.83842830 |
| 51 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.78371953 |
| 52 | Cell cycle_Homo sapiens_hsa04110 | 0.76445427 |
| 53 | Colorectal cancer_Homo sapiens_hsa05210 | 0.76314895 |
| 54 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.71591797 |
| 55 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.70166157 |
| 56 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.65983014 |
| 57 | Mineral absorption_Homo sapiens_hsa04978 | 0.62796354 |
| 58 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.62633943 |
| 59 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.59137122 |
| 60 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.58681240 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.57431201 |
| 62 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.55102922 |
| 63 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.52911794 |
| 64 | Gap junction_Homo sapiens_hsa04540 | 0.51573522 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49265565 |
| 66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.44582459 |
| 67 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.44368395 |
| 68 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.44333117 |
| 69 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.43922572 |
| 70 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.42740179 |
| 71 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.38713276 |
| 72 | Viral myocarditis_Homo sapiens_hsa05416 | 0.38657032 |
| 73 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.37194897 |
| 74 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.37082051 |
| 75 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.37009897 |
| 76 | Thyroid cancer_Homo sapiens_hsa05216 | 0.36956379 |
| 77 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.36778647 |
| 78 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.35474374 |
| 79 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.34722466 |
| 80 | Legionellosis_Homo sapiens_hsa05134 | 0.34656819 |
| 81 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.33709952 |
| 82 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.27832840 |
| 83 | Prostate cancer_Homo sapiens_hsa05215 | 0.25848798 |
| 84 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25693048 |
| 85 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.22960813 |
| 86 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.22760007 |
| 87 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.22692147 |
| 88 | Endometrial cancer_Homo sapiens_hsa05213 | 0.21787100 |
| 89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.19974857 |
| 90 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.19512327 |
| 91 | Melanoma_Homo sapiens_hsa05218 | 0.18602508 |
| 92 | Focal adhesion_Homo sapiens_hsa04510 | 0.18561068 |
| 93 | Pathways in cancer_Homo sapiens_hsa05200 | 0.17847095 |
| 94 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.14480501 |
| 95 | HTLV-I infection_Homo sapiens_hsa05166 | 0.13525414 |
| 96 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.12097617 |
| 97 | Prion diseases_Homo sapiens_hsa05020 | 0.11319668 |
| 98 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.10685878 |
| 99 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.09137269 |
| 100 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.06245173 |

