TMEM232

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1multicellular organism reproduction (GO:0032504)9.74748765
2acrosome assembly (GO:0001675)9.08954024
3sperm-egg recognition (GO:0035036)8.96116764
4motile cilium assembly (GO:0044458)8.84677557
5cell wall macromolecule catabolic process (GO:0016998)8.59202282
6cell wall macromolecule metabolic process (GO:0044036)8.59202282
7binding of sperm to zona pellucida (GO:0007339)8.43110853
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.28106113
9plasma membrane fusion (GO:0045026)8.22263108
10male meiosis (GO:0007140)8.16691975
11acrosome reaction (GO:0007340)8.13612607
12cell-cell recognition (GO:0009988)7.93596910
13reproduction (GO:0000003)7.91975108
14spermatid development (GO:0007286)7.63800768
15regulation of cilium movement (GO:0003352)7.13625123
16synaptonemal complex organization (GO:0070193)6.98093602
17single fertilization (GO:0007338)6.78023256
18synaptonemal complex assembly (GO:0007130)6.62277808
19DNA methylation involved in gamete generation (GO:0043046)6.51044390
20fertilization (GO:0009566)6.11400681
21ventricular system development (GO:0021591)6.05542234
22male meiosis I (GO:0007141)5.99016300
23axoneme assembly (GO:0035082)5.94426231
24spermatogenesis (GO:0007283)5.66922206
25male gamete generation (GO:0048232)5.64899592
26microtubule severing (GO:0051013)5.52790189
27sperm capacitation (GO:0048240)5.44835363
28meiotic cell cycle (GO:0051321)5.41005173
29gamete generation (GO:0007276)5.40890806
30negative regulation of inclusion body assembly (GO:0090084)5.25463614
31microtubule depolymerization (GO:0007019)5.03582396
32nucleoside diphosphate phosphorylation (GO:0006165)4.95302758
33meiosis I (GO:0007127)4.89946404
34meiotic nuclear division (GO:0007126)4.88952452
35chromosome organization involved in meiosis (GO:0070192)4.76831314
36GTP biosynthetic process (GO:0006183)4.76367595
37germ cell development (GO:0007281)4.67715299
38cellular process involved in reproduction in multicellular organism (GO:0022412)4.62254782
39regulation of inclusion body assembly (GO:0090083)4.45301820
40regulation of meiosis I (GO:0060631)4.38706257
41multicellular organismal reproductive process (GO:0048609)4.25757494
42protein polyglutamylation (GO:0018095)4.16737779
43UTP biosynthetic process (GO:0006228)4.14989652
44regulation of microtubule-based movement (GO:0060632)4.02479397
45organic cation transport (GO:0015695)3.99794008
46intraciliary transport (GO:0042073)3.94699561
47calcium ion-dependent exocytosis (GO:0017156)3.89898248
48cell recognition (GO:0008037)3.88173575
49retinal cone cell development (GO:0046549)3.81533774
50gene silencing by RNA (GO:0031047)3.72966159
51nonmotile primary cilium assembly (GO:0035058)3.71916145
52cilium organization (GO:0044782)3.71757546
53monoubiquitinated protein deubiquitination (GO:0035520)3.71122253
54UTP metabolic process (GO:0046051)3.70537042
55cell projection assembly (GO:0030031)3.70142142
56protein localization to cilium (GO:0061512)3.65227358
57photoreceptor cell maintenance (GO:0045494)3.62794421
58microtubule-based movement (GO:0007018)3.57677796
59glycerol ether metabolic process (GO:0006662)3.55498113
60cilium assembly (GO:0042384)3.53889351
61meiotic cell cycle process (GO:1903046)3.52351679
62smoothened signaling pathway (GO:0007224)3.50420664
63neural tube formation (GO:0001841)3.49191164
64left/right pattern formation (GO:0060972)3.44680999
65cilium morphogenesis (GO:0060271)3.41772256
66seminiferous tubule development (GO:0072520)3.41485981
67centriole replication (GO:0007099)3.39933854
68left/right axis specification (GO:0070986)3.39035796
69cellular component assembly involved in morphogenesis (GO:0010927)3.35916686
70spermatid nucleus differentiation (GO:0007289)3.33264567
71chromosome condensation (GO:0030261)3.32313466
72retinal rod cell development (GO:0046548)3.31773583
73ether metabolic process (GO:0018904)3.29432096
74negative regulation of organelle assembly (GO:1902116)3.28734721
75centriole assembly (GO:0098534)3.23266848
76cornea development in camera-type eye (GO:0061303)3.17826681
77multicellular organismal development (GO:0007275)3.17110173
78regulation of centriole replication (GO:0046599)3.12353322
79determination of left/right symmetry (GO:0007368)3.10736252
80lateral ventricle development (GO:0021670)3.10664217
81regulation of acrosome reaction (GO:0060046)3.08687608
82DNA packaging (GO:0006323)3.05783920
83female gamete generation (GO:0007292)3.03577781
84CTP biosynthetic process (GO:0006241)3.03409880
85CTP metabolic process (GO:0046036)3.03409880
86guanosine-containing compound biosynthetic process (GO:1901070)3.02089765
87microtubule bundle formation (GO:0001578)3.00426108
88presynaptic membrane assembly (GO:0097105)3.00369252
89regulation of meiosis (GO:0040020)2.99297162
90microtubule polymerization or depolymerization (GO:0031109)2.98724711
91determination of bilateral symmetry (GO:0009855)2.98397227
92primary alcohol catabolic process (GO:0034310)2.97924495
93one-carbon compound transport (GO:0019755)2.90027292
94specification of symmetry (GO:0009799)2.89855309
95regulation of spindle checkpoint (GO:0090231)2.89148396
96single strand break repair (GO:0000012)2.87465489
97diterpenoid biosynthetic process (GO:0016102)2.86946252
98genitalia morphogenesis (GO:0035112)2.85577772
99synapsis (GO:0007129)2.84462546
100DNA methylation (GO:0006306)2.83042222
101DNA alkylation (GO:0006305)2.83042222
102regulation of collateral sprouting (GO:0048670)2.82145629
103mitotic sister chromatid cohesion (GO:0007064)2.82085149
104inner ear receptor stereocilium organization (GO:0060122)2.79681341
105vitamin transmembrane transport (GO:0035461)2.74355573
106presynaptic membrane organization (GO:0097090)2.73023928
107intra-S DNA damage checkpoint (GO:0031573)2.71640053
108histone exchange (GO:0043486)2.71484017
109positive regulation of meiosis (GO:0045836)2.70485289
110pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.69929902
111regulation of female gonad development (GO:2000194)2.67625083
112photoreceptor cell development (GO:0042461)2.67516447
113behavioral response to nicotine (GO:0035095)2.67285043
114detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.64293512
115glycolytic process (GO:0006096)2.63259915
116positive regulation of meiotic cell cycle (GO:0051446)2.62545872
117pyrimidine nucleobase catabolic process (GO:0006208)2.62508188
118oocyte maturation (GO:0001556)2.62002321
119negative regulation of cytosolic calcium ion concentration (GO:0051481)2.60915688
120terpenoid biosynthetic process (GO:0016114)2.58151626
121appendage development (GO:0048736)2.56715801
122limb development (GO:0060173)2.56715801
123cytoplasmic microtubule organization (GO:0031122)2.56335980
124organelle assembly (GO:0070925)2.54358327
125spinal cord motor neuron differentiation (GO:0021522)2.52652393
126retinoic acid metabolic process (GO:0042573)2.49103555
127eye photoreceptor cell development (GO:0042462)2.45518498
128limb bud formation (GO:0060174)2.45400193
129exogenous drug catabolic process (GO:0042738)2.44411814
130microtubule-based process (GO:0007017)2.42374790
131eye photoreceptor cell differentiation (GO:0001754)2.42112165
132photoreceptor cell differentiation (GO:0046530)2.42112165
133ethanol metabolic process (GO:0006067)2.41677485
134brain morphogenesis (GO:0048854)2.40129021
135positive regulation of oligodendrocyte differentiation (GO:0048714)2.36745424
136response to xenobiotic stimulus (GO:0009410)2.34843945
137nucleobase catabolic process (GO:0046113)2.34012894
138pyrimidine-containing compound transmembrane transport (GO:0072531)2.32429895
139cellular ketone body metabolic process (GO:0046950)2.32383311
140negative regulation of transcription regulatory region DNA binding (GO:2000678)2.32012010
141somite development (GO:0061053)2.30670268
142postsynaptic membrane organization (GO:0001941)2.28045834
143negative regulation of T cell differentiation in thymus (GO:0033085)2.26429316
144glomerular epithelial cell development (GO:0072310)2.25261311
145aldehyde catabolic process (GO:0046185)2.23187868
146cochlea development (GO:0090102)2.22874803
147neuron fate determination (GO:0048664)2.22260312
148establishment of tissue polarity (GO:0007164)2.22161301
149establishment of planar polarity (GO:0001736)2.22161301
150response to nitrosative stress (GO:0051409)2.20698549
151gamma-aminobutyric acid transport (GO:0015812)2.20009285
152response to pheromone (GO:0019236)2.19571817
153histone H2A acetylation (GO:0043968)2.17401942
154glutathione derivative metabolic process (GO:1901685)2.16510996
155glutathione derivative biosynthetic process (GO:1901687)2.16510996
156drug catabolic process (GO:0042737)2.16315638
157regulation of timing of cell differentiation (GO:0048505)2.15749428
158auditory behavior (GO:0031223)2.15381944
159negative regulation of dendrite development (GO:2000171)2.13583733
160establishment or maintenance of monopolar cell polarity (GO:0061339)2.13566232
161establishment of monopolar cell polarity (GO:0061162)2.13566232
162L-fucose metabolic process (GO:0042354)2.11534294
163cilium or flagellum-dependent cell motility (GO:0001539)11.6934767
164axonemal dynein complex assembly (GO:0070286)11.3327651
165fusion of sperm to egg plasma membrane (GO:0007342)10.7752335
166epithelial cilium movement (GO:0003351)10.5955526
167cilium movement (GO:0003341)10.4616395
168sperm motility (GO:0030317)10.0991766
169piRNA metabolic process (GO:0034587)10.0151774

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse7.05735962
2EZH2_22144423_ChIP-Seq_EOC_Human4.25523698
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.08214519
4GBX2_23144817_ChIP-Seq_PC3_Human3.21116270
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.90196108
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.71033610
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.64201894
8PCGF2_27294783_Chip-Seq_ESCs_Mouse2.33647787
9IGF1R_20145208_ChIP-Seq_DFB_Human2.25185364
10KAP1_22055183_ChIP-Seq_ESCs_Mouse2.23626098
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.23066460
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.22013590
13VDR_22108803_ChIP-Seq_LS180_Human2.18854090
14CTBP1_25329375_ChIP-Seq_LNCAP_Human2.11172592
15GATA1_26923725_Chip-Seq_HPCs_Mouse2.11124428
16PIAS1_25552417_ChIP-Seq_VCAP_Human2.10389318
17P300_19829295_ChIP-Seq_ESCs_Human2.09833578
18HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.02032791
19EWS_26573619_Chip-Seq_HEK293_Human2.01770858
20ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.00995843
21STAT6_21828071_ChIP-Seq_BEAS2B_Human1.98275468
22PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.87552235
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.87041403
24SUZ12_27294783_Chip-Seq_NPCs_Mouse1.83710026
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83174908
26EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.80309610
27NFE2_27457419_Chip-Seq_LIVER_Mouse1.79668929
28* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.77496303
29TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.76203498
30* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.75483128
31NR3C1_21868756_ChIP-Seq_MCF10A_Human1.75173582
32STAT1_17558387_ChIP-Seq_HELA_Human1.73821761
33STAT3_23295773_ChIP-Seq_U87_Human1.72311655
34* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.71986412
35RNF2_27304074_Chip-Seq_NSC_Mouse1.71185888
36CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.70596838
37TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.70218482
38CBX2_27304074_Chip-Seq_ESCs_Mouse1.69715611
39ELK4_26923725_Chip-Seq_MESODERM_Mouse1.68018650
40SMAD3_21741376_ChIP-Seq_EPCs_Human1.66941282
41ER_23166858_ChIP-Seq_MCF-7_Human1.62429306
42* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.61564763
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59436252
44UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56546870
45PCGF2_27294783_Chip-Seq_NPCs_Mouse1.56261023
46AR_25329375_ChIP-Seq_VCAP_Human1.55855464
47E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.54490906
48SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53200610
49MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.53055000
50* KDM2B_26808549_Chip-Seq_REH_Human1.52681313
51NANOG_18555785_Chip-Seq_ESCs_Mouse1.52190617
52TAL1_26923725_Chip-Seq_HPCs_Mouse1.51831219
53WDR5_24793694_ChIP-Seq_LNCAP_Human1.49942125
54TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.49783987
55POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.49783987
56TCF4_22108803_ChIP-Seq_LS180_Human1.48268213
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47751060
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43297308
59CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.42621609
60EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.42057138
61DROSHA_22980978_ChIP-Seq_HELA_Human1.41945804
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.41679275
63RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.41669969
64CRX_20693478_ChIP-Seq_RETINA_Mouse1.41614573
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40441441
66FUS_26573619_Chip-Seq_HEK293_Human1.39025039
67RUNX2_22187159_ChIP-Seq_PCA_Human1.38155778
68AR_21572438_ChIP-Seq_LNCaP_Human1.36474018
69TAF15_26573619_Chip-Seq_HEK293_Human1.35320764
70FLI1_21867929_ChIP-Seq_TH2_Mouse1.35172440
71OCT4_18555785_Chip-Seq_ESCs_Mouse1.33405881
72GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.32965272
73CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.32725232
74FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.31427039
75KLF5_20875108_ChIP-Seq_MESCs_Mouse1.31405989
76POU3F2_20337985_ChIP-ChIP_501MEL_Human1.30040270
77P53_22387025_ChIP-Seq_ESCs_Mouse1.28325593
78STAT3_18555785_Chip-Seq_ESCs_Mouse1.26640943
79* SMAD4_21799915_ChIP-Seq_A2780_Human1.25921067
80CMYC_18555785_Chip-Seq_ESCs_Mouse1.25641983
81FOXM1_26456572_ChIP-Seq_MCF-7_Human1.25563647
82GATA3_21867929_ChIP-Seq_TH1_Mouse1.25086138
83ARNT_22903824_ChIP-Seq_MCF-7_Human1.24107232
84ZNF274_21170338_ChIP-Seq_K562_Hela1.23634054
85RBPJ_22232070_ChIP-Seq_NCS_Mouse1.23510620
86OCT4_21477851_ChIP-Seq_ESCs_Mouse1.22866695
87CBP_20019798_ChIP-Seq_JUKART_Human1.21258572
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.21258572
89ESRRB_18555785_Chip-Seq_ESCs_Mouse1.20474482
90KLF4_18555785_Chip-Seq_ESCs_Mouse1.20265399
91TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20009845
92EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.19982474
93CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.18872067
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.18672358
95SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.17999420
96CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.17765425
97P300_18555785_Chip-Seq_ESCs_Mouse1.17761046
98AHR_22903824_ChIP-Seq_MCF-7_Human1.17678185
99EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17035527
100SOX2_18555785_Chip-Seq_ESCs_Mouse1.16215213
101SUZ12_18555785_Chip-Seq_ESCs_Mouse1.16173545
102* SOX2_22085726_ChIP-Seq_NPCs_Mouse1.15898353
103TP53_16413492_ChIP-PET_HCT116_Human1.15777646
104NANOG_19829295_ChIP-Seq_ESCs_Human1.15730322
105SOX2_19829295_ChIP-Seq_ESCs_Human1.15730322
106MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15404653
107TP53_18474530_ChIP-ChIP_U2OS_Human1.14311044
108SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.13923606
109FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12305449
110BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12165941
111CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10772954
112ZFX_18555785_Chip-Seq_ESCs_Mouse1.10492032
113* REST_21632747_ChIP-Seq_MESCs_Mouse1.10427758
114FOXA1_25329375_ChIP-Seq_VCAP_Human1.10421532
115FOXA1_27270436_Chip-Seq_PROSTATE_Human1.10421532
116GATA3_21867929_ChIP-Seq_CD8_Mouse1.09624280
117GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09498209
118BCAT_22108803_ChIP-Seq_LS180_Human1.09496668
119E2F1_18555785_Chip-Seq_ESCs_Mouse1.09369324
120PRDM14_20953172_ChIP-Seq_ESCs_Human1.08980101
121CDX2_22108803_ChIP-Seq_LS180_Human1.08570456
122ERG_20517297_ChIP-Seq_VCAP_Human1.08265964
123CTCF_18555785_Chip-Seq_ESCs_Mouse1.08204496
124SOX2_21211035_ChIP-Seq_LN229_Gbm1.08053106
125* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.08026593
126TBL1_22424771_ChIP-Seq_293T_Human1.07858697
127TCF4_23295773_ChIP-Seq_U87_Human1.07079959
128ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06501987
129TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.06093038
130SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05677509
131TP53_22573176_ChIP-Seq_HFKS_Human1.05654679
132SALL1_21062744_ChIP-ChIP_HESCs_Human1.05484891
133NMYC_18555785_Chip-Seq_ESCs_Mouse1.04855623
134LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.04576886
135RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04453336
136STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04382420
137GF1_26923725_Chip-Seq_HPCs_Mouse1.03706763
138PU1_27457419_Chip-Seq_LIVER_Mouse1.03212654
139ETV1_20927104_ChIP-Seq_GIST48_Human1.02774701
140SMAD4_21741376_ChIP-Seq_EPCs_Human1.02491546
141P53_21459846_ChIP-Seq_SAOS-2_Human1.02414722
142* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01822709
143RUNX1_27457419_Chip-Seq_LIVER_Mouse1.00508587
144PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00463839
145ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.99722850
146NFYB_21822215_ChIP-Seq_K562_Human0.99028147
147SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.98446118
148SMAD_19615063_ChIP-ChIP_OVARY_Human0.98187471

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001929_abnormal_gametogenesis5.30194271
2MP0008877_abnormal_DNA_methylation5.23815367
3MP0003698_abnormal_male_reproductive5.09919083
4MP0002653_abnormal_ependyma_morphology4.32445381
5MP0003646_muscle_fatigue3.96923473
6MP0002210_abnormal_sex_determination3.67354317
7MP0002161_abnormal_fertility/fecundity3.13990634
8MP0003011_delayed_dark_adaptation3.00490218
9MP0000653_abnormal_sex_gland2.98715929
10MP0001145_abnormal_male_reproductive2.95128724
11MP0008875_abnormal_xenobiotic_pharmacok2.72313444
12MP0003718_maternal_effect2.63123538
13MP0004043_abnormal_pH_regulation2.45276182
14MP0004133_heterotaxia2.39497999
15MP0008789_abnormal_olfactory_epithelium2.24129998
16MP0000569_abnormal_digit_pigmentation2.21293465
17MP0002102_abnormal_ear_morphology2.15280639
18MP0002638_abnormal_pupillary_reflex2.13497123
19MP0001485_abnormal_pinna_reflex2.10298821
20MP0005377_hearing/vestibular/ear_phenot2.00928811
21MP0003878_abnormal_ear_physiology2.00928811
22MP0005410_abnormal_fertilization11.6716700
23MP0005646_abnormal_pituitary_gland1.97961726
24MP0000383_abnormal_hair_follicle1.88312714
25MP0005451_abnormal_body_composition1.81038156
26MP0003195_calcinosis1.74274867
27MP0005394_taste/olfaction_phenotype1.71736200
28MP0005499_abnormal_olfactory_system1.71736200
29MP0009780_abnormal_chondrocyte_physiolo1.65676771
30MP0002160_abnormal_reproductive_system1.65036300
31MP0001486_abnormal_startle_reflex1.64466502
32MP0009745_abnormal_behavioral_response1.58496355
33MP0002272_abnormal_nervous_system1.57468953
34MP0005670_abnormal_white_adipose1.55495854
35MP0002282_abnormal_trachea_morphology1.54424926
36MP0002735_abnormal_chemical_nociception1.53260844
37MP0000778_abnormal_nervous_system1.47965810
38MP0000566_synostosis1.47961176
39MP0005395_other_phenotype1.47618860
40MP0003699_abnormal_female_reproductive1.47392705
41MP0010094_abnormal_chromosome_stability1.44763247
42MP0010678_abnormal_skin_adnexa1.44666794
43MP0001119_abnormal_female_reproductive1.43795828
44MP0002938_white_spotting1.42933217
45MP0004885_abnormal_endolymph1.35525789
46MP0000026_abnormal_inner_ear1.30369942
47MP0002876_abnormal_thyroid_physiology1.28669884
48MP0005623_abnormal_meninges_morphology1.28007360
49MP0008995_early_reproductive_senescence1.27640520
50MP0010386_abnormal_urinary_bladder1.25393732
51MP0003890_abnormal_embryonic-extraembry1.25200937
52MP0002557_abnormal_social/conspecific_i1.22643099
53MP0002064_seizures1.20159621
54MP0005195_abnormal_posterior_eye1.17610658
55MP0003787_abnormal_imprinting1.15465775
56MP0001970_abnormal_pain_threshold1.14983030
57MP0002277_abnormal_respiratory_mucosa1.14005575
58MP0003136_yellow_coat_color1.13993463
59MP0002909_abnormal_adrenal_gland1.10239739
60MP0001963_abnormal_hearing_physiology1.10047216
61MP0002132_abnormal_respiratory_system1.09469215
62MP0001765_abnormal_ion_homeostasis1.08666559
63MP0004742_abnormal_vestibular_system1.07257862
64MP0002233_abnormal_nose_morphology1.05384760
65MP0002067_abnormal_sensory_capabilities1.05153640
66MP0000579_abnormal_nail_morphology1.04897921
67MP0005391_vision/eye_phenotype1.04838798
68MP0003122_maternal_imprinting1.04791604
69MP0002234_abnormal_pharynx_morphology1.04151435
70MP0009046_muscle_twitch1.03453344
71MP0002751_abnormal_autonomic_nervous1.03333510
72MP0001984_abnormal_olfaction1.03262534
73MP0004147_increased_porphyrin_level1.02754483
74MP0005647_abnormal_sex_gland1.00240688
75MP0005389_reproductive_system_phenotype1.00218557
76MP0005645_abnormal_hypothalamus_physiol1.00008356
77MP0002063_abnormal_learning/memory/cond0.99607658
78MP0003786_premature_aging0.98442684
79MP0003635_abnormal_synaptic_transmissio0.97470176
80MP0002229_neurodegeneration0.97223697
81MP0002752_abnormal_somatic_nervous0.96477738
82MP0008058_abnormal_DNA_repair0.96160261
83MP0003937_abnormal_limbs/digits/tail_de0.95734328
84MP0008872_abnormal_physiological_respon0.94690394
85MP0001324_abnormal_eye_pigmentation0.93913318
86MP0000372_irregular_coat_pigmentation0.93530282
87MP0003950_abnormal_plasma_membrane0.93449136
88MP0001293_anophthalmia0.93203197
89MP0001501_abnormal_sleep_pattern0.89615470
90MP0000955_abnormal_spinal_cord0.89007384
91MP0005174_abnormal_tail_pigmentation0.88448136
92MP0002882_abnormal_neuron_morphology0.87320095
93MP0000647_abnormal_sebaceous_gland0.86601059
94MP0004215_abnormal_myocardial_fiber0.86407621
95MP0003693_abnormal_embryo_hatching0.86204604
96MP0004142_abnormal_muscle_tone0.85883416
97MP0005248_abnormal_Harderian_gland0.85638210
98MP0002249_abnormal_larynx_morphology0.85290098
99MP0008004_abnormal_stomach_pH0.84784405
100MP0004233_abnormal_muscle_weight0.83684172
101MP0001502_abnormal_circadian_rhythm0.83383608
102MP0005085_abnormal_gallbladder_physiolo0.83258452
103MP0004145_abnormal_muscle_electrophysio0.81917746
104MP0005423_abnormal_somatic_nervous0.81712163
105MP0005551_abnormal_eye_electrophysiolog0.78227672
106MP0005666_abnormal_adipose_tissue0.77128314
107MP0002971_abnormal_brown_adipose0.74736980
108MP0004019_abnormal_vitamin_homeostasis0.74630702
109MP0002736_abnormal_nociception_after0.72756976
110MP0002168_other_aberrant_phenotype0.68926949
111MP0001905_abnormal_dopamine_level0.65322071
112MP0003315_abnormal_perineum_morphology0.64285510
113MP0008057_abnormal_DNA_replication0.63461204
114MP0005253_abnormal_eye_physiology0.62666887
115MP0000462_abnormal_digestive_system0.61910750
116MP0000631_abnormal_neuroendocrine_gland0.61713816
117MP0003111_abnormal_nucleus_morphology0.60834456
118MP0004859_abnormal_synaptic_plasticity0.58804261
119MP0003077_abnormal_cell_cycle0.58414873
120MP0004036_abnormal_muscle_relaxation0.58392085
121MP0008932_abnormal_embryonic_tissue0.57656554
122MP0003880_abnormal_central_pattern0.56805116
123MP0003861_abnormal_nervous_system0.56175487
124MP0000427_abnormal_hair_cycle0.55846854
125MP0003329_amyloid_beta_deposits0.55072441
126MP0001529_abnormal_vocalization0.54354184
127MP0001986_abnormal_taste_sensitivity0.52756964
128MP0004270_analgesia0.51074929
129MP0009250_abnormal_appendicular_skeleto0.50224161
130MP0009115_abnormal_fat_cell0.50205926
131MP0002139_abnormal_hepatobiliary_system0.50142163
132MP0003121_genomic_imprinting0.49953537
133MP0001851_eye_inflammation0.47097101
134MP0002084_abnormal_developmental_patter0.46888446
135MP0002928_abnormal_bile_duct0.46665024
136MP0004264_abnormal_extraembryonic_tissu0.44869134
137MP0001968_abnormal_touch/_nociception0.44059592
138MP0002085_abnormal_embryonic_tissue0.43903813
139MP0000639_abnormal_adrenal_gland0.43321883
140MP0000751_myopathy0.42877906
141MP0002269_muscular_atrophy0.42436116
142MP0001440_abnormal_grooming_behavior0.42415841
143MP0002152_abnormal_brain_morphology0.41479172
144MP0002572_abnormal_emotion/affect_behav0.41237745
145MP0001958_emphysema0.40913697
146MP0006072_abnormal_retinal_apoptosis0.40806084
147MP0003879_abnormal_hair_cell0.40233041
148MP0002734_abnormal_mechanical_nocicepti0.39056936
149MP0001727_abnormal_embryo_implantation0.37853818
150MP0000534_abnormal_ureter_morphology0.37210116
151MP0004957_abnormal_blastocyst_morpholog0.36832985
152MP0009697_abnormal_copulation0.36687756
153MP0002109_abnormal_limb_morphology0.36507204
154MP0003942_abnormal_urinary_system0.35088306
155MP0005187_abnormal_penis_morphology0.34920812
156MP0006292_abnormal_olfactory_placode0.34731809
157MP0006276_abnormal_autonomic_nervous0.34471709
158MP0002837_dystrophic_cardiac_calcinosis0.33767749
159MP0000432_abnormal_head_morphology0.33151950
160MP0002970_abnormal_white_adipose0.32862984
161MP0001849_ear_inflammation0.31977549
162MP0002295_abnormal_pulmonary_circulatio0.31851199
163MP0000749_muscle_degeneration0.31105612

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.18093233
2Abnormal respiratory motile cilium morphology (HP:0005938)8.94888104
3Abnormal respiratory epithelium morphology (HP:0012253)8.94888104
4Rhinitis (HP:0012384)8.74430910
5Chronic bronchitis (HP:0004469)7.94866807
6Infertility (HP:0000789)5.87625296
7Nasal polyposis (HP:0100582)5.19562758
8Bronchiectasis (HP:0002110)5.07438448
9Male infertility (HP:0003251)4.72417281
10Abnormality of the nasal mucosa (HP:0000433)4.21717052
11Bronchitis (HP:0012387)4.09200356
12Nephronophthisis (HP:0000090)3.98514133
13Tubulointerstitial nephritis (HP:0001970)3.53461555
14Recurrent sinusitis (HP:0011108)3.42937132
15Abnormality of the renal medulla (HP:0100957)3.10941301
16Recurrent otitis media (HP:0000403)3.03833393
17Anencephaly (HP:0002323)2.76887231
18Molar tooth sign on MRI (HP:0002419)2.72667411
19Abnormality of midbrain morphology (HP:0002418)2.72667411
20Medial flaring of the eyebrow (HP:0010747)2.63150206
21Sclerocornea (HP:0000647)2.60236162
22Pancreatic fibrosis (HP:0100732)2.52555886
23Abnormal spermatogenesis (HP:0008669)2.52539478
24Tubulointerstitial abnormality (HP:0001969)2.46594932
25Hyperventilation (HP:0002883)2.42744677
26Abnormality of the dental pulp (HP:0006479)2.40935594
27Abnormality of dentin (HP:0010299)2.36267018
28Furrowed tongue (HP:0000221)2.31007209
29Tubular atrophy (HP:0000092)2.19695554
30Postaxial foot polydactyly (HP:0001830)2.15081534
31Abnormality of the dental root (HP:0006486)2.10605865
32Taurodontia (HP:0000679)2.10605865
33Abnormality of permanent molar morphology (HP:0011071)2.10605865
34Cholecystitis (HP:0001082)2.05432997
35Abnormal gallbladder physiology (HP:0012438)2.05432997
36Gait imbalance (HP:0002141)2.00736388
37True hermaphroditism (HP:0010459)2.00678998
38Congenital primary aphakia (HP:0007707)2.00672925
39Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.8657804
40Absent/shortened dynein arms (HP:0200106)11.0370039
41Dynein arm defect of respiratory motile cilia (HP:0012255)11.0370039
42Abnormal respiratory motile cilium physiology (HP:0012261)10.7414006
43Median cleft lip (HP:0000161)1.99637657
44Impulsivity (HP:0100710)1.96838452
45Azoospermia (HP:0000027)1.96754542
46Abnormal rod and cone electroretinograms (HP:0008323)1.94779382
47Abnormality of molar morphology (HP:0011070)1.93260461
48Abnormality of molar (HP:0011077)1.93260461
49Papillary thyroid carcinoma (HP:0002895)1.89421428
50Congenital hepatic fibrosis (HP:0002612)1.88387414
51Microglossia (HP:0000171)1.83276694
52Stage 5 chronic kidney disease (HP:0003774)1.82157911
53Supernumerary spleens (HP:0009799)1.81249093
54Aplasia/Hypoplasia of the tongue (HP:0010295)1.79035869
55Chromosomal breakage induced by crosslinking agents (HP:0003221)1.78148965
56Hyperactive renin-angiotensin system (HP:0000841)1.77299420
57Chromsome breakage (HP:0040012)1.76482592
58Cystic liver disease (HP:0006706)1.75973261
59Genital tract atresia (HP:0001827)1.74134280
60Focal motor seizures (HP:0011153)1.72912590
61Narrow forehead (HP:0000341)1.71997238
62Absent rod-and cone-mediated responses on ERG (HP:0007688)1.70945544
63Abnormality of the renal cortex (HP:0011035)1.70643993
64Poor coordination (HP:0002370)1.70445658
65Nephrogenic diabetes insipidus (HP:0009806)1.70077280
66Postaxial hand polydactyly (HP:0001162)1.69985027
67Chronic hepatic failure (HP:0100626)1.69976441
68Chronic otitis media (HP:0000389)1.69282827
69Aplasia/Hypoplasia of the spleen (HP:0010451)1.68437049
70Prominent nasal bridge (HP:0000426)1.66696192
71Chronic sinusitis (HP:0011109)1.66457693
72Absent speech (HP:0001344)1.66178640
73Bony spicule pigmentary retinopathy (HP:0007737)1.66057254
74Asplenia (HP:0001746)1.65716648
75Tubulointerstitial fibrosis (HP:0005576)1.65713325
76Broad foot (HP:0001769)1.65571921
77Retinitis pigmentosa (HP:0000510)1.64457808
78Pancreatic cysts (HP:0001737)1.63974201
79Polyuria (HP:0000103)1.63905672
80Aganglionic megacolon (HP:0002251)1.63841568
81Decreased circulating renin level (HP:0003351)1.63227429
82Intestinal atresia (HP:0011100)1.61909509
83Gonadotropin excess (HP:0000837)1.58170639
84Aplasia/Hypoplasia of the lens (HP:0008063)1.57424664
85Specific learning disability (HP:0001328)1.55639400
86Abnormality of macular pigmentation (HP:0008002)1.55428105
87Abnormality of renal excretion (HP:0011036)1.54003344
88Congenital stationary night blindness (HP:0007642)1.53201450
89Vaginal atresia (HP:0000148)1.53094425
90Recurrent bronchitis (HP:0002837)1.52089389
91Bell-shaped thorax (HP:0001591)1.51922756
92Highly arched eyebrow (HP:0002553)1.51833233
93Short ribs (HP:0000773)1.51664935
94Fibular hypoplasia (HP:0003038)1.51242458
95Abolished electroretinogram (ERG) (HP:0000550)1.50354505
96Insulin-resistant diabetes mellitus (HP:0000831)1.49359517
97Type II lissencephaly (HP:0007260)1.48110987
98Renal dysplasia (HP:0000110)1.46546775
99Nephropathy (HP:0000112)1.46103891
100Multicystic kidney dysplasia (HP:0000003)1.44515414
101Hyperphosphatemia (HP:0002905)1.42929153
102Polydipsia (HP:0001959)1.38282586
103Abnormal drinking behavior (HP:0030082)1.38282586
104Gaze-evoked nystagmus (HP:0000640)1.37272661
105Decreased testicular size (HP:0008734)1.37048185
106Chorioretinal coloboma (HP:0000567)1.36578242
107Abnormality of lateral ventricle (HP:0030047)1.36413585
108Broad-based gait (HP:0002136)1.36324854
109Attenuation of retinal blood vessels (HP:0007843)1.35917918
110Renal salt wasting (HP:0000127)1.35785774
111Oculomotor apraxia (HP:0000657)1.34848962
112Male pseudohermaphroditism (HP:0000037)1.34801311
113Gastrointestinal atresia (HP:0002589)1.34634133
114Bile duct proliferation (HP:0001408)1.33869643
115Abnormal biliary tract physiology (HP:0012439)1.33869643
116Widely spaced teeth (HP:0000687)1.33542468
117Hyperaldosteronism (HP:0000859)1.32596732
118Anophthalmia (HP:0000528)1.32501728
119Dandy-Walker malformation (HP:0001305)1.31948827
120Abdominal situs inversus (HP:0003363)1.31883499
121Abnormality of abdominal situs (HP:0011620)1.31883499
122Abnormality of renal resorption (HP:0011038)1.31781621
123Ectopic kidney (HP:0000086)1.31371418
124Nephroblastoma (Wilms tumor) (HP:0002667)1.31336605
125Optic nerve coloboma (HP:0000588)1.30626122
126Oligohydramnios (HP:0001562)1.29815521
127Cortical dysplasia (HP:0002539)1.29518559
128Amyotrophic lateral sclerosis (HP:0007354)1.26807501
129Cone-rod dystrophy (HP:0000548)1.26540896
130Facial cleft (HP:0002006)1.24700433
131Short thorax (HP:0010306)1.24697927
132Hypoplasia of the capital femoral epiphysis (HP:0003090)1.24642184
133Vascular calcification (HP:0004934)1.23731061
134Hypergonadotropic hypogonadism (HP:0000815)1.20884525
135Embryonal renal neoplasm (HP:0011794)1.20778735
136Atelectasis (HP:0100750)1.20373839
137Decreased central vision (HP:0007663)1.17499703
138Sloping forehead (HP:0000340)1.16952432
139Aplasia/Hypoplasia of the fibula (HP:0006492)1.15706121
140Astigmatism (HP:0000483)1.14656338
141Occipital encephalocele (HP:0002085)1.14575545
142Abnormality of the lower motor neuron (HP:0002366)1.14479686
143Preaxial hand polydactyly (HP:0001177)1.14069498

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.68746151
2PDK37.68746151
3PDK24.79652403
4FRK4.69334039
5PRKD34.16046984
6TESK13.41060074
7CASK2.93850162
8MST42.75072344
9MAP4K22.52867404
10LATS12.17428375
11BCR2.03576040
12PNCK2.00982619
13MUSK1.98829462
14WNK41.92444946
15PLK41.90963965
16TTK1.82677145
17ICK1.81602183
18PTK2B1.75466613
19STK391.70832150
20TAOK31.69916139
21MAP3K61.68257187
22NEK21.63705877
23STK38L1.61968797
24TNIK1.61022709
25TRIM281.57336383
26ADRBK21.56595922
27BRAF1.55996365
28ACVR1B1.54489512
29ERBB31.53691375
30INSRR1.52013414
31MARK11.50002444
32STK31.40993065
33MAP3K91.39751001
34STK381.39313095
35WEE11.38435265
36EEF2K1.36138538
37CHEK21.33141378
38ERBB41.33067464
39TSSK61.32847923
40ZAK1.31256490
41LATS21.29766163
42MAPK151.23550235
43CDC71.21359362
44KSR21.21286616
45TYRO31.16274715
46OXSR11.14584612
47MAP3K41.13249350
48ARAF1.10141199
49CCNB11.09251234
50MOS1.08859745
51PDK11.07026453
52PAK31.05596086
53MKNK21.04597079
54MELK1.02431113
55VRK10.99024650
56NTRK30.96957397
57CSNK1G20.96646697
58BRSK20.96464935
59NEK10.96194442
60NTRK20.96060763
61FGFR20.95252374
62TLK10.93526588
63MAP2K70.91331864
64CDK190.90614363
65PRKCE0.86216875
66STK100.79776828
67NME10.79062625
68CSNK1G10.78629782
69FER0.76142786
70ADRBK10.67650301
71TGFBR10.67463735
72TAOK10.67112599
73CSNK1G30.66332846
74BMPR20.66034768
75PDPK10.65940123
76PLK10.65761842
77CSNK1A1L0.64472152
78PKN10.63703795
79WNK10.63028279
80MAPKAPK50.62629905
81MINK10.61811589
82PINK10.59736901
83MKNK10.58386231
84RAF10.58079563
85PAK60.57746250
86CAMKK20.54806138
87PRKCI0.54023120
88DYRK30.50977319
89MAPKAPK30.50627949
90PRKAA10.50171011
91DAPK20.49087794
92CHEK10.46260048
93MAPK130.45884122
94MAP3K50.45131484
95EPHA20.44128209
96PRKACA0.43303910
97ATM0.42793045
98SGK20.42685067
99NLK0.42345786
100MAP3K20.41960624
101CDK120.41743448
102EPHA30.40776769
103CSNK1A10.39876373
104PHKG20.39176111
105PHKG10.39176111
106ERBB20.39006475
107PRKCZ0.38239144
108DYRK1A0.37303299
109MAP2K40.37099511
110LMTK20.36863055
111MAP3K130.36616878
112NUAK10.35257925
113RET0.35204714
114BMPR1B0.34877805
115CDK90.34753273
116AURKA0.31403997
117CAMK2A0.31230800
118SGK4940.29628771
119SGK2230.29628771
120CDK30.28284851
121STK240.27291492
122PRKACB0.26531992
123KSR10.26436818
124CAMK40.25639414
125CAMK1G0.25380159
126AKT30.24766613
127ATR0.23867496
128PLK20.23379261
129DMPK0.23374744
130NEK60.23372727
131MARK20.22701914
132PRKD20.22536556
133PRKAA20.21741584
134PRKCQ0.20392601
135DYRK1B0.19989516
136MAP3K80.19560805
137DYRK20.19385408
138PAK10.19205697
139PRKG10.18590649
140WNK30.18223607
141PRKCG0.13545466
142NEK90.12958512
143AURKB0.11504437
144IRAK10.10524071
145CDK10.07633157
146OBSCN0.07553313
147EPHA40.07050712
148CDK150.06910074
149GRK10.06816422
150RPS6KB10.06770371
151STK110.06690606
152CSNK1D0.05587870
153PLK30.05421371
154ROCK10.05327618
155GSK3B0.04962153
156TRPM70.04572639
157CDK180.04427756
158CDK40.04158859

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.93471468
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.35193771
3Basal transcription factors_Homo sapiens_hsa030223.18759764
4Linoleic acid metabolism_Homo sapiens_hsa005913.06284572
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.02685430
6Pyruvate metabolism_Homo sapiens_hsa006202.99376250
7Propanoate metabolism_Homo sapiens_hsa006402.73734862
8Oocyte meiosis_Homo sapiens_hsa041142.55874489
9Dorso-ventral axis formation_Homo sapiens_hsa043202.52332308
10Fanconi anemia pathway_Homo sapiens_hsa034602.41915744
11Fatty acid biosynthesis_Homo sapiens_hsa000612.41089321
12Ether lipid metabolism_Homo sapiens_hsa005652.38180450
13Butanoate metabolism_Homo sapiens_hsa006502.25778803
14Phototransduction_Homo sapiens_hsa047442.21538702
15Glucagon signaling pathway_Homo sapiens_hsa049222.18600273
16Histidine metabolism_Homo sapiens_hsa003402.16569940
17Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.11618174
18Ovarian steroidogenesis_Homo sapiens_hsa049132.06050048
19beta-Alanine metabolism_Homo sapiens_hsa004101.98908637
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.96425432
21Protein export_Homo sapiens_hsa030601.87265898
22Huntingtons disease_Homo sapiens_hsa050161.86628355
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.74705423
24Primary bile acid biosynthesis_Homo sapiens_hsa001201.72704653
25Caffeine metabolism_Homo sapiens_hsa002321.69428569
26ABC transporters_Homo sapiens_hsa020101.64204585
27Glycerophospholipid metabolism_Homo sapiens_hsa005641.63626297
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.61953354
29Amphetamine addiction_Homo sapiens_hsa050311.53810553
30Cell cycle_Homo sapiens_hsa041101.53519732
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.43565230
32RNA degradation_Homo sapiens_hsa030181.39153692
33Peroxisome_Homo sapiens_hsa041461.39070053
34Tyrosine metabolism_Homo sapiens_hsa003501.39020072
35PPAR signaling pathway_Homo sapiens_hsa033201.38610150
36Nitrogen metabolism_Homo sapiens_hsa009101.37677853
37Glycerolipid metabolism_Homo sapiens_hsa005611.32292356
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.31818622
39Steroid hormone biosynthesis_Homo sapiens_hsa001401.31799107
40Circadian rhythm_Homo sapiens_hsa047101.31243981
41Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.31010694
42Tryptophan metabolism_Homo sapiens_hsa003801.26571796
43Phenylalanine metabolism_Homo sapiens_hsa003601.24791481
44Oxidative phosphorylation_Homo sapiens_hsa001901.24311737
45Glycosaminoglycan degradation_Homo sapiens_hsa005311.21878616
46Carbohydrate digestion and absorption_Homo sapiens_hsa049731.20509753
47Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.19637667
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.16816330
49Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14678192
50Selenocompound metabolism_Homo sapiens_hsa004501.14536791
51Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.13675993
52Pentose phosphate pathway_Homo sapiens_hsa000301.11921354
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.11796548
54GABAergic synapse_Homo sapiens_hsa047271.11096558
55Purine metabolism_Homo sapiens_hsa002301.09389792
56Retinol metabolism_Homo sapiens_hsa008301.08669304
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.07362334
58Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.05882837
59Mineral absorption_Homo sapiens_hsa049781.03829106
60Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.02587258
61Steroid biosynthesis_Homo sapiens_hsa001001.00491663
62Arachidonic acid metabolism_Homo sapiens_hsa005900.99413298
63Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.97247905
64Renin secretion_Homo sapiens_hsa049240.97186020
65Cardiac muscle contraction_Homo sapiens_hsa042600.95931175
66Regulation of autophagy_Homo sapiens_hsa041400.95120899
67Morphine addiction_Homo sapiens_hsa050320.95006006
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.93573235
69Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.93371925
70Basal cell carcinoma_Homo sapiens_hsa052170.92798424
71Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.90739766
72Glutathione metabolism_Homo sapiens_hsa004800.89296031
73Serotonergic synapse_Homo sapiens_hsa047260.85381697
74Long-term potentiation_Homo sapiens_hsa047200.85193437
75Insulin secretion_Homo sapiens_hsa049110.84158895
76Inositol phosphate metabolism_Homo sapiens_hsa005620.83952994
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83310629
78Estrogen signaling pathway_Homo sapiens_hsa049150.81523189
79Synaptic vesicle cycle_Homo sapiens_hsa047210.81263608
80Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.80583266
81Parkinsons disease_Homo sapiens_hsa050120.80266212
82RNA transport_Homo sapiens_hsa030130.79815021
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.79287630
84Calcium signaling pathway_Homo sapiens_hsa040200.77962446
85Collecting duct acid secretion_Homo sapiens_hsa049660.77469136
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.76144996
87Homologous recombination_Homo sapiens_hsa034400.76096417
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72310159
89mRNA surveillance pathway_Homo sapiens_hsa030150.71972293
90Nicotine addiction_Homo sapiens_hsa050330.70875825
91Tight junction_Homo sapiens_hsa045300.70662406
92Glutamatergic synapse_Homo sapiens_hsa047240.70071331
93Taste transduction_Homo sapiens_hsa047420.68855143
94Gastric acid secretion_Homo sapiens_hsa049710.66220884
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65584129
96Hedgehog signaling pathway_Homo sapiens_hsa043400.65427385
97Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63845134
98VEGF signaling pathway_Homo sapiens_hsa043700.63230941
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62387360
100Alzheimers disease_Homo sapiens_hsa050100.61779858
101cAMP signaling pathway_Homo sapiens_hsa040240.61253122
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.61034824
103AMPK signaling pathway_Homo sapiens_hsa041520.60114156
104Salivary secretion_Homo sapiens_hsa049700.58186376
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56602231
106Olfactory transduction_Homo sapiens_hsa047400.54683255
107Non-homologous end-joining_Homo sapiens_hsa034500.54398103
108Fructose and mannose metabolism_Homo sapiens_hsa000510.54340654
109Cocaine addiction_Homo sapiens_hsa050300.53776685
110Chemical carcinogenesis_Homo sapiens_hsa052040.52366255
111Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.51122372
112Carbon metabolism_Homo sapiens_hsa012000.48030567
113Choline metabolism in cancer_Homo sapiens_hsa052310.47821788
114Fatty acid elongation_Homo sapiens_hsa000620.47798468
115GnRH signaling pathway_Homo sapiens_hsa049120.47162160
116Axon guidance_Homo sapiens_hsa043600.45841922
117Nucleotide excision repair_Homo sapiens_hsa034200.45577998
118Fatty acid metabolism_Homo sapiens_hsa012120.43729354
119Bile secretion_Homo sapiens_hsa049760.42734150
120Folate biosynthesis_Homo sapiens_hsa007900.41783399
121Oxytocin signaling pathway_Homo sapiens_hsa049210.41341579
122Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.41293805
123Long-term depression_Homo sapiens_hsa047300.40990809
124Wnt signaling pathway_Homo sapiens_hsa043100.40652341
125Fatty acid degradation_Homo sapiens_hsa000710.40571596
126Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40131803
127RNA polymerase_Homo sapiens_hsa030200.39989472
128Arginine and proline metabolism_Homo sapiens_hsa003300.39288325
129Aldosterone synthesis and secretion_Homo sapiens_hsa049250.38693249
130Circadian entrainment_Homo sapiens_hsa047130.35821571
131Thyroid hormone synthesis_Homo sapiens_hsa049180.35257709
132Dopaminergic synapse_Homo sapiens_hsa047280.35051942
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32955278
134Metabolic pathways_Homo sapiens_hsa011000.32700676
135Pyrimidine metabolism_Homo sapiens_hsa002400.32663567
136Pancreatic secretion_Homo sapiens_hsa049720.28452265
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28259889
138TGF-beta signaling pathway_Homo sapiens_hsa043500.27114681
139Hippo signaling pathway_Homo sapiens_hsa043900.25594756
140Sphingolipid metabolism_Homo sapiens_hsa006000.24715352
141Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.24305726
142Biosynthesis of amino acids_Homo sapiens_hsa012300.22937100
143Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22422715
144p53 signaling pathway_Homo sapiens_hsa041150.21740638

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