

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 6.74260195 |
| 2 | response to muscle activity (GO:0014850) | 6.55561868 |
| 3 | neurofilament cytoskeleton organization (GO:0060052) | 6.53521694 |
| 4 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 6.53073513 |
| 5 | actin-myosin filament sliding (GO:0033275) | 6.31204326 |
| 6 | muscle filament sliding (GO:0030049) | 6.31204326 |
| 7 | neuronal action potential (GO:0019228) | 6.29801820 |
| 8 | regulation of skeletal muscle contraction (GO:0014819) | 6.24958779 |
| 9 | detection of temperature stimulus (GO:0016048) | 6.01024370 |
| 10 | plasma membrane repair (GO:0001778) | 5.99086484 |
| 11 | skeletal muscle contraction (GO:0003009) | 5.98171260 |
| 12 | myofibril assembly (GO:0030239) | 5.88007372 |
| 13 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 5.85072752 |
| 14 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 5.85072752 |
| 15 | neuronal action potential propagation (GO:0019227) | 5.77713454 |
| 16 | membrane depolarization during action potential (GO:0086010) | 5.52309883 |
| 17 | skeletal muscle adaptation (GO:0043501) | 5.40475462 |
| 18 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 5.35147517 |
| 19 | response to inactivity (GO:0014854) | 5.23908022 |
| 20 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 5.14879327 |
| 21 | actin-mediated cell contraction (GO:0070252) | 5.13365198 |
| 22 | regulation of cell communication by electrical coupling (GO:0010649) | 5.11479771 |
| 23 | muscle cell cellular homeostasis (GO:0046716) | 4.92555907 |
| 24 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 4.87053439 |
| 25 | glycogen catabolic process (GO:0005980) | 4.82174872 |
| 26 | muscle cell fate commitment (GO:0042693) | 4.76452982 |
| 27 | skeletal muscle tissue regeneration (GO:0043403) | 4.74677469 |
| 28 | purine nucleotide salvage (GO:0032261) | 4.55378683 |
| 29 | skeletal muscle tissue development (GO:0007519) | 4.52614635 |
| 30 | neuromuscular synaptic transmission (GO:0007274) | 4.50274119 |
| 31 | glucan catabolic process (GO:0009251) | 4.50155398 |
| 32 | negative regulation of protein localization to cell surface (GO:2000009) | 4.49305609 |
| 33 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.48887243 |
| 34 | cardiac myofibril assembly (GO:0055003) | 4.47440873 |
| 35 | behavioral response to pain (GO:0048266) | 4.40140078 |
| 36 | negative regulation of dendrite morphogenesis (GO:0050774) | 4.37338854 |
| 37 | carnitine shuttle (GO:0006853) | 4.35237379 |
| 38 | skeletal muscle fiber development (GO:0048741) | 4.32366733 |
| 39 | oxygen transport (GO:0015671) | 4.31627905 |
| 40 | cardiac muscle contraction (GO:0060048) | 4.30897432 |
| 41 | actomyosin structure organization (GO:0031032) | 4.16167761 |
| 42 | heart contraction (GO:0060047) | 4.12372043 |
| 43 | heart process (GO:0003015) | 4.12372043 |
| 44 | cellular polysaccharide catabolic process (GO:0044247) | 4.11652222 |
| 45 | regulation of actin filament-based movement (GO:1903115) | 4.10964702 |
| 46 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.97475647 |
| 47 | proline transport (GO:0015824) | 3.95818731 |
| 48 | striated muscle contraction (GO:0006941) | 3.95069533 |
| 49 | muscle organ morphogenesis (GO:0048644) | 3.94734552 |
| 50 | actin filament-based movement (GO:0030048) | 3.91966070 |
| 51 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.90363972 |
| 52 | response to activity (GO:0014823) | 3.89666204 |
| 53 | polysaccharide catabolic process (GO:0000272) | 3.88863707 |
| 54 | negative regulation of complement activation (GO:0045916) | 3.88721091 |
| 55 | response to pain (GO:0048265) | 3.84678170 |
| 56 | adenosine metabolic process (GO:0046085) | 3.78176734 |
| 57 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.75227933 |
| 58 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.69281106 |
| 59 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.69281106 |
| 60 | myotube cell development (GO:0014904) | 3.69192831 |
| 61 | muscle organ development (GO:0007517) | 3.66964873 |
| 62 | muscle structure development (GO:0061061) | 3.66109943 |
| 63 | gas transport (GO:0015669) | 3.62728152 |
| 64 | muscle tissue morphogenesis (GO:0060415) | 3.62505612 |
| 65 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.59332575 |
| 66 | cell communication involved in cardiac conduction (GO:0086065) | 3.59075916 |
| 67 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.57899460 |
| 68 | fatty acid transmembrane transport (GO:1902001) | 3.53444462 |
| 69 | peripheral nervous system neuron development (GO:0048935) | 3.52733730 |
| 70 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.51881246 |
| 71 | urinary tract smooth muscle contraction (GO:0014848) | 3.51077468 |
| 72 | action potential (GO:0001508) | 3.50028863 |
| 73 | creatine metabolic process (GO:0006600) | 3.47991657 |
| 74 | axon cargo transport (GO:0008088) | 3.47925902 |
| 75 | myotube differentiation (GO:0014902) | 3.46480543 |
| 76 | muscle contraction (GO:0006936) | 3.45820389 |
| 77 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.45130954 |
| 78 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.43797321 |
| 79 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.41880844 |
| 80 | striated muscle adaptation (GO:0014888) | 3.39595292 |
| 81 | glycogen metabolic process (GO:0005977) | 3.39472122 |
| 82 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.39373010 |
| 83 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 3.38160965 |
| 84 | positive regulation of muscle hypertrophy (GO:0014742) | 3.38160965 |
| 85 | muscle atrophy (GO:0014889) | 3.37933010 |
| 86 | sarcomere organization (GO:0045214) | 3.35468205 |
| 87 | cell migration in hindbrain (GO:0021535) | 3.33496910 |
| 88 | glucan metabolic process (GO:0044042) | 3.32300188 |
| 89 | cellular glucan metabolic process (GO:0006073) | 3.32300188 |
| 90 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 3.32188382 |
| 91 | cellular potassium ion homeostasis (GO:0030007) | 3.30928537 |
| 92 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.22072124 |
| 93 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.22072124 |
| 94 | ubiquinone biosynthetic process (GO:0006744) | 3.20393468 |
| 95 | endoplasmic reticulum organization (GO:0007029) | 3.20113173 |
| 96 | negative regulation of protein activation cascade (GO:2000258) | 3.17237685 |
| 97 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.16214056 |
| 98 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.15936168 |
| 99 | regulation of relaxation of muscle (GO:1901077) | 3.15623685 |
| 100 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.15219814 |
| 101 | relaxation of muscle (GO:0090075) | 3.14636986 |
| 102 | synaptic transmission, cholinergic (GO:0007271) | 3.13717743 |
| 103 | regulation of striated muscle contraction (GO:0006942) | 3.13243769 |
| 104 | carnitine transmembrane transport (GO:1902603) | 3.11855029 |
| 105 | striated muscle tissue development (GO:0014706) | 3.09017804 |
| 106 | membrane repolarization (GO:0086009) | 3.07554065 |
| 107 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.07135067 |
| 108 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.07084210 |
| 109 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 3.07078385 |
| 110 | glycogen biosynthetic process (GO:0005978) | 3.06964920 |
| 111 | glucan biosynthetic process (GO:0009250) | 3.06964920 |
| 112 | response to ATP (GO:0033198) | 3.05663950 |
| 113 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.05526176 |
| 114 | muscle system process (GO:0003012) | 3.03580230 |
| 115 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.03502936 |
| 116 | sodium ion export (GO:0071436) | 3.01898979 |
| 117 | enteric nervous system development (GO:0048484) | 3.01591888 |
| 118 | myoblast fusion (GO:0007520) | 3.01231924 |
| 119 | regulation of membrane repolarization (GO:0060306) | 3.00138413 |
| 120 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 2.98515749 |
| 121 | positive regulation of vesicle fusion (GO:0031340) | 2.98173606 |
| 122 | intermediate filament-based process (GO:0045103) | 2.98124485 |
| 123 | sodium ion transmembrane transport (GO:0035725) | 2.97145305 |
| 124 | myoblast migration (GO:0051451) | 2.97090298 |
| 125 | striated muscle atrophy (GO:0014891) | 2.96876576 |
| 126 | negative regulation of muscle contraction (GO:0045932) | 2.96419602 |
| 127 | striated muscle cell development (GO:0055002) | 2.96418723 |
| 128 | intermediate filament organization (GO:0045109) | 2.95242205 |
| 129 | regulation of histone phosphorylation (GO:0033127) | 2.95045613 |
| 130 | regulation of sequestering of triglyceride (GO:0010889) | 2.94379673 |
| 131 | negative regulation of cation channel activity (GO:2001258) | 2.94043218 |
| 132 | cardiac muscle hypertrophy (GO:0003300) | 2.93156352 |
| 133 | muscle fiber development (GO:0048747) | 2.92179489 |
| 134 | regulation of membrane depolarization (GO:0003254) | 2.91922586 |
| 135 | intermediate filament cytoskeleton organization (GO:0045104) | 2.91187568 |
| 136 | regulation of muscle system process (GO:0090257) | 2.91034497 |
| 137 | ubiquinone metabolic process (GO:0006743) | 2.90316906 |
| 138 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.89488718 |
| 139 | regulation of muscle contraction (GO:0006937) | 2.88620834 |
| 140 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.88109013 |
| 141 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 2.86752216 |
| 142 | regulation of sarcomere organization (GO:0060297) | 2.86268013 |
| 143 | regulation of sodium ion transmembrane transport (GO:1902305) | 2.85852534 |
| 144 | negative regulation of microtubule polymerization (GO:0031115) | 2.85174796 |
| 145 | DNA damage induced protein phosphorylation (GO:0006975) | 2.84341508 |
| 146 | potassium ion import (GO:0010107) | 2.83166174 |
| 147 | regulation of muscle hypertrophy (GO:0014743) | 2.83161538 |
| 148 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 2.81697239 |
| 149 | respiratory electron transport chain (GO:0022904) | 2.81163129 |
| 150 | regulation of the force of heart contraction (GO:0002026) | 2.80936760 |
| 151 | striated muscle hypertrophy (GO:0014897) | 2.80113654 |
| 152 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.76613772 |
| 153 | electron transport chain (GO:0022900) | 2.76144470 |
| 154 | muscle tissue development (GO:0060537) | 2.76124210 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.51009755 |
| 2 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.42470084 |
| 3 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.00854129 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.83808632 |
| 5 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.67490434 |
| 6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.63639906 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.61820911 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.51962178 |
| 9 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.48077347 |
| 10 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.42905056 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.40213364 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.37446906 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.37406350 |
| 14 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.19451061 |
| 15 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.13944116 |
| 16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.06831428 |
| 17 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.03025506 |
| 18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.95260681 |
| 19 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.94987277 |
| 20 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.94987277 |
| 21 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.89199969 |
| 22 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.87803025 |
| 23 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.87151145 |
| 24 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.78229976 |
| 25 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.76694946 |
| 26 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.75754543 |
| 27 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.74729011 |
| 28 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.69168884 |
| 29 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.68094819 |
| 30 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.65624838 |
| 31 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.64763580 |
| 32 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.61775780 |
| 33 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.57807390 |
| 34 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.56964028 |
| 35 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.56385217 |
| 36 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.54445281 |
| 37 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.53694157 |
| 38 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.53121632 |
| 39 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.52329041 |
| 40 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.51947224 |
| 41 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.50257346 |
| 42 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.49253150 |
| 43 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.48937025 |
| 44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.48914409 |
| 45 | KDM2B_26808549_Chip-Seq_K562_Human | 1.47683071 |
| 46 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.46325042 |
| 47 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.46093321 |
| 48 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.44698495 |
| 49 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.44016866 |
| 50 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.43822060 |
| 51 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.43135267 |
| 52 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.40607771 |
| 53 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.40217704 |
| 54 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.39079424 |
| 55 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.38657316 |
| 56 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.36770359 |
| 57 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.36759357 |
| 58 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.36138360 |
| 59 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.35936916 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32370577 |
| 61 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.31946616 |
| 62 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.29595709 |
| 63 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.27537102 |
| 64 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.26938457 |
| 65 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.26112921 |
| 66 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.24504655 |
| 67 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.24079481 |
| 68 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.23803430 |
| 69 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.22342558 |
| 70 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.21779882 |
| 71 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.21779702 |
| 72 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.21779702 |
| 73 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.21102037 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.21048073 |
| 75 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.20994712 |
| 76 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.20197318 |
| 77 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.19704057 |
| 78 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.19691735 |
| 79 | SA1_27219007_Chip-Seq_Bcells_Human | 1.19220449 |
| 80 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.18668297 |
| 81 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.18472458 |
| 82 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.16944377 |
| 83 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.14418383 |
| 84 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.11982767 |
| 85 | KLF4_19829295_ChIP-Seq_ESCs_Human | 1.11737452 |
| 86 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.10661722 |
| 87 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.09655636 |
| 88 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.09543055 |
| 89 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.09391513 |
| 90 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.08981531 |
| 91 | P300_19829295_ChIP-Seq_ESCs_Human | 1.08132939 |
| 92 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.07827444 |
| 93 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.06710976 |
| 94 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05872314 |
| 95 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.05242881 |
| 96 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.05175374 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.05024626 |
| 98 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.04897179 |
| 99 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.04592931 |
| 100 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03566705 |
| 101 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.03363542 |
| 102 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.03332904 |
| 103 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.02602099 |
| 104 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02207150 |
| 105 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.01411901 |
| 106 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.01373628 |
| 107 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.00719777 |
| 108 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00411300 |
| 109 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 1.00267411 |
| 110 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.99240365 |
| 111 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.98865520 |
| 112 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.98818039 |
| 113 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98623701 |
| 114 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.98588565 |
| 115 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.98588565 |
| 116 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.97875908 |
| 117 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.97432341 |
| 118 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.96859612 |
| 119 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.96775389 |
| 120 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.95946338 |
| 121 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.95787294 |
| 122 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.93375633 |
| 123 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.93297740 |
| 124 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.93005498 |
| 125 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.92428273 |
| 126 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.92345102 |
| 127 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.91938903 |
| 128 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.91646272 |
| 129 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.91646272 |
| 130 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.91512425 |
| 131 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.91399094 |
| 132 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.91180631 |
| 133 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.90801486 |
| 134 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.90687207 |
| 135 | * LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90312213 |
| 136 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.89282799 |
| 137 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.89103930 |
| 138 | AR_19668381_ChIP-Seq_PC3_Human | 0.88665659 |
| 139 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.88589966 |
| 140 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.88514221 |
| 141 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87523891 |
| 142 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.86857232 |
| 143 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.86677768 |
| 144 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.85392657 |
| 145 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85391460 |
| 146 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.85359069 |
| 147 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.84761974 |
| 148 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.83939152 |
| 149 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.83260599 |
| 150 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.83041655 |
| 151 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.82848718 |
| 152 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.82848718 |
| 153 | CJUN_26792858_Chip-Seq_BT549_Human | 0.82535211 |
| 154 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.81979326 |
| 155 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.81284414 |
| 156 | AR_25329375_ChIP-Seq_VCAP_Human | 0.80969678 |
| 157 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.78377362 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001968_abnormal_touch/_nociception | 5.97217470 |
| 2 | MP0002736_abnormal_nociception_after | 5.85560619 |
| 3 | MP0002735_abnormal_chemical_nociception | 5.79246321 |
| 4 | MP0004145_abnormal_muscle_electrophysio | 5.32584181 |
| 5 | MP0000749_muscle_degeneration | 4.36735716 |
| 6 | MP0004270_analgesia | 3.82203406 |
| 7 | MP0000751_myopathy | 3.69022938 |
| 8 | MP0001986_abnormal_taste_sensitivity | 3.67441689 |
| 9 | MP0003646_muscle_fatigue | 3.60381552 |
| 10 | MP0002733_abnormal_thermal_nociception | 3.32996862 |
| 11 | MP0000747_muscle_weakness | 3.32825332 |
| 12 | MP0004858_abnormal_nervous_system | 3.24626078 |
| 13 | MP0002734_abnormal_mechanical_nocicepti | 3.20731977 |
| 14 | MP0006276_abnormal_autonomic_nervous | 2.87894625 |
| 15 | MP0004036_abnormal_muscle_relaxation | 2.80712587 |
| 16 | MP0001970_abnormal_pain_threshold | 2.65722841 |
| 17 | MP0000759_abnormal_skeletal_muscle | 2.45607142 |
| 18 | MP0002106_abnormal_muscle_physiology | 2.45082026 |
| 19 | MP0002269_muscular_atrophy | 2.41902172 |
| 20 | MP0002837_dystrophic_cardiac_calcinosis | 2.39603009 |
| 21 | MP0004130_abnormal_muscle_cell | 2.37498231 |
| 22 | MP0003950_abnormal_plasma_membrane | 2.23639612 |
| 23 | MP0005451_abnormal_body_composition | 2.14210719 |
| 24 | MP0005369_muscle_phenotype | 2.03858229 |
| 25 | MP0005187_abnormal_penis_morphology | 1.99611546 |
| 26 | MP0004087_abnormal_muscle_fiber | 1.98096066 |
| 27 | MP0005620_abnormal_muscle_contractility | 1.93444274 |
| 28 | MP0003656_abnormal_erythrocyte_physiolo | 1.77024171 |
| 29 | MP0000750_abnormal_muscle_regeneration | 1.63907726 |
| 30 | MP0002272_abnormal_nervous_system | 1.61056417 |
| 31 | MP0005083_abnormal_biliary_tract | 1.59958414 |
| 32 | MP0004859_abnormal_synaptic_plasticity | 1.59007916 |
| 33 | MP0002067_abnormal_sensory_capabilities | 1.56732836 |
| 34 | MP0004885_abnormal_endolymph | 1.47378174 |
| 35 | MP0000372_irregular_coat_pigmentation | 1.45631061 |
| 36 | MP0004233_abnormal_muscle_weight | 1.43409323 |
| 37 | MP0004147_increased_porphyrin_level | 1.34599983 |
| 38 | MP0005266_abnormal_metabolism | 1.30363726 |
| 39 | MP0003329_amyloid_beta_deposits | 1.25073342 |
| 40 | MP0004043_abnormal_pH_regulation | 1.21594758 |
| 41 | MP0002184_abnormal_innervation | 1.15421525 |
| 42 | MP0006036_abnormal_mitochondrial_physio | 1.11605090 |
| 43 | MP0004811_abnormal_neuron_physiology | 1.10912927 |
| 44 | MP0002876_abnormal_thyroid_physiology | 1.10041104 |
| 45 | MP0002822_catalepsy | 1.09854264 |
| 46 | MP0001299_abnormal_eye_distance/ | 1.09810145 |
| 47 | MP0002108_abnormal_muscle_morphology | 1.09764167 |
| 48 | MP0004185_abnormal_adipocyte_glucose | 1.07547587 |
| 49 | MP0002332_abnormal_exercise_endurance | 1.06645978 |
| 50 | MP0001270_distended_abdomen | 1.05135816 |
| 51 | MP0002127_abnormal_cardiovascular_syste | 1.03782011 |
| 52 | MP0006138_congestive_heart_failure | 1.00502752 |
| 53 | MP0002751_abnormal_autonomic_nervous | 0.99592589 |
| 54 | MP0003011_delayed_dark_adaptation | 0.99074914 |
| 55 | MP0002972_abnormal_cardiac_muscle | 0.98816556 |
| 56 | MP0000955_abnormal_spinal_cord | 0.98257393 |
| 57 | MP0004084_abnormal_cardiac_muscle | 0.95919127 |
| 58 | MP0003879_abnormal_hair_cell | 0.95800321 |
| 59 | MP0003806_abnormal_nucleotide_metabolis | 0.95722989 |
| 60 | MP0003635_abnormal_synaptic_transmissio | 0.95516378 |
| 61 | MP0000681_abnormal_thyroid_gland | 0.95249180 |
| 62 | MP0003045_fibrosis | 0.93960151 |
| 63 | MP0000733_abnormal_muscle_development | 0.93320805 |
| 64 | MP0009053_abnormal_anal_canal | 0.91271682 |
| 65 | MP0008260_abnormal_autophagy | 0.91051095 |
| 66 | MP0003880_abnormal_central_pattern | 0.85540445 |
| 67 | MP0004484_altered_response_of | 0.85029014 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.83746155 |
| 69 | MP0001348_abnormal_lacrimal_gland | 0.83497696 |
| 70 | MP0005330_cardiomyopathy | 0.82691403 |
| 71 | MP0003633_abnormal_nervous_system | 0.82596920 |
| 72 | MP0004215_abnormal_myocardial_fiber | 0.80324747 |
| 73 | MP0003283_abnormal_digestive_organ | 0.79190179 |
| 74 | MP0009046_muscle_twitch | 0.79119315 |
| 75 | MP0008569_lethality_at_weaning | 0.75422377 |
| 76 | MP0010368_abnormal_lymphatic_system | 0.73224843 |
| 77 | MP0010771_integument_phenotype | 0.69110218 |
| 78 | MP0002066_abnormal_motor_capabilities/c | 0.68956884 |
| 79 | MP0002909_abnormal_adrenal_gland | 0.67228010 |
| 80 | MP0005670_abnormal_white_adipose | 0.66808396 |
| 81 | MP0000003_abnormal_adipose_tissue | 0.66755421 |
| 82 | MP0005084_abnormal_gallbladder_morpholo | 0.65751401 |
| 83 | MP0002229_neurodegeneration | 0.64926536 |
| 84 | MP0000604_amyloidosis | 0.63541524 |
| 85 | MP0005595_abnormal_vascular_smooth | 0.63495664 |
| 86 | MP0002063_abnormal_learning/memory/cond | 0.63018181 |
| 87 | MP0008874_decreased_physiological_sensi | 0.62873489 |
| 88 | MP0000920_abnormal_myelination | 0.62857300 |
| 89 | MP0001879_abnormal_lymphatic_vessel | 0.62325632 |
| 90 | MP0002882_abnormal_neuron_morphology | 0.62224374 |
| 91 | MP0002064_seizures | 0.62121254 |
| 92 | MP0001661_extended_life_span | 0.60895306 |
| 93 | MP0010030_abnormal_orbit_morphology | 0.60588521 |
| 94 | MP0009745_abnormal_behavioral_response | 0.60531012 |
| 95 | MP0008961_abnormal_basal_metabolism | 0.60444070 |
| 96 | MP0004142_abnormal_muscle_tone | 0.60310844 |
| 97 | MP0001485_abnormal_pinna_reflex | 0.60152295 |
| 98 | MP0003631_nervous_system_phenotype | 0.59192442 |
| 99 | MP0005666_abnormal_adipose_tissue | 0.59007026 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.58282140 |
| 101 | MP0003828_pulmonary_edema | 0.57948592 |
| 102 | MP0003221_abnormal_cardiomyocyte_apopto | 0.57829741 |
| 103 | MP0008775_abnormal_heart_ventricle | 0.55297119 |
| 104 | MP0001486_abnormal_startle_reflex | 0.54784141 |
| 105 | MP0005423_abnormal_somatic_nervous | 0.54718562 |
| 106 | MP0003634_abnormal_glial_cell | 0.54247740 |
| 107 | MP0000767_abnormal_smooth_muscle | 0.51822368 |
| 108 | MP0002160_abnormal_reproductive_system | 0.51724475 |
| 109 | MP0000534_abnormal_ureter_morphology | 0.51466222 |
| 110 | MP0000427_abnormal_hair_cycle | 0.51214207 |
| 111 | MP0001984_abnormal_olfaction | 0.48629211 |
| 112 | MP0009250_abnormal_appendicular_skeleto | 0.48507306 |
| 113 | MP0005365_abnormal_bile_salt | 0.48353178 |
| 114 | MP0000013_abnormal_adipose_tissue | 0.48280906 |
| 115 | MP0005375_adipose_tissue_phenotype | 0.47994375 |
| 116 | MP0002971_abnormal_brown_adipose | 0.47672681 |
| 117 | MP0009780_abnormal_chondrocyte_physiolo | 0.46891677 |
| 118 | MP0002638_abnormal_pupillary_reflex | 0.46630402 |
| 119 | MP0000266_abnormal_heart_morphology | 0.45081798 |
| 120 | MP0001440_abnormal_grooming_behavior | 0.43440346 |
| 121 | MP0003137_abnormal_impulse_conducting | 0.43222978 |
| 122 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.43167280 |
| 123 | MP0008872_abnormal_physiological_respon | 0.42115444 |
| 124 | MP0004085_abnormal_heartbeat | 0.41549448 |
| 125 | MP0005535_abnormal_body_temperature | 0.40180730 |
| 126 | MP0004134_abnormal_chest_morphology | 0.40150993 |
| 127 | MP0010630_abnormal_cardiac_muscle | 0.40081296 |
| 128 | MP0003195_calcinosis | 0.40001532 |
| 129 | MP0001188_hyperpigmentation | 0.39557724 |
| 130 | MP0005452_abnormal_adipose_tissue | 0.39136193 |
| 131 | MP0002752_abnormal_somatic_nervous | 0.38476489 |
| 132 | MP0001544_abnormal_cardiovascular_syste | 0.38405107 |
| 133 | MP0005385_cardiovascular_system_phenoty | 0.38405107 |
| 134 | MP0000230_abnormal_systemic_arterial | 0.38212213 |
| 135 | MP0000538_abnormal_urinary_bladder | 0.38178221 |
| 136 | MP0002572_abnormal_emotion/affect_behav | 0.36591656 |
| 137 | MP0004510_myositis | 0.35223765 |
| 138 | MP0010234_abnormal_vibrissa_follicle | 0.34795789 |
| 139 | MP0005645_abnormal_hypothalamus_physiol | 0.34681133 |
| 140 | MP0002128_abnormal_blood_circulation | 0.34590767 |
| 141 | MP0002078_abnormal_glucose_homeostasis | 0.34446282 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Distal arthrogryposis (HP:0005684) | 7.20128714 |
| 2 | Exercise-induced myalgia (HP:0003738) | 6.92816057 |
| 3 | Muscle fiber inclusion bodies (HP:0100299) | 6.83307002 |
| 4 | Exercise-induced muscle cramps (HP:0003710) | 6.63631686 |
| 5 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 6.58406788 |
| 6 | Nemaline bodies (HP:0003798) | 6.14395706 |
| 7 | Ulnar claw (HP:0001178) | 5.99289896 |
| 8 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.41111017 |
| 9 | Hyporeflexia of lower limbs (HP:0002600) | 5.22324425 |
| 10 | Difficulty running (HP:0009046) | 5.07311601 |
| 11 | Myotonia (HP:0002486) | 4.95313918 |
| 12 | Myopathic facies (HP:0002058) | 4.94287516 |
| 13 | Absent phalangeal crease (HP:0006109) | 4.77925536 |
| 14 | Type 1 muscle fiber predominance (HP:0003803) | 4.76788185 |
| 15 | Muscle stiffness (HP:0003552) | 4.74949708 |
| 16 | Calf muscle hypertrophy (HP:0008981) | 4.63271104 |
| 17 | Round ear (HP:0100830) | 4.52581234 |
| 18 | Ulnar deviation of the wrist (HP:0003049) | 4.45840768 |
| 19 | Myoglobinuria (HP:0002913) | 4.37210290 |
| 20 | Segmental peripheral demyelination/remyelination (HP:0003481) | 4.23849673 |
| 21 | Muscle fiber splitting (HP:0003555) | 4.20164025 |
| 22 | Termporal pattern (HP:0011008) | 4.11338687 |
| 23 | Insidious onset (HP:0003587) | 4.11338687 |
| 24 | Abnormal finger flexion creases (HP:0006143) | 3.96869365 |
| 25 | EMG: myopathic abnormalities (HP:0003458) | 3.78573295 |
| 26 | Calcaneovalgus deformity (HP:0001848) | 3.73682188 |
| 27 | Increased connective tissue (HP:0009025) | 3.73150424 |
| 28 | Areflexia of lower limbs (HP:0002522) | 3.58751423 |
| 29 | Type 2 muscle fiber atrophy (HP:0003554) | 3.55225003 |
| 30 | Foot dorsiflexor weakness (HP:0009027) | 3.50409571 |
| 31 | Rhabdomyolysis (HP:0003201) | 3.43561357 |
| 32 | Weak cry (HP:0001612) | 3.40837362 |
| 33 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.35785861 |
| 34 | Deformed tarsal bones (HP:0008119) | 3.35527904 |
| 35 | Dysautonomia (HP:0002459) | 3.33371376 |
| 36 | Fetal akinesia sequence (HP:0001989) | 3.29290895 |
| 37 | Steppage gait (HP:0003376) | 3.24614126 |
| 38 | Muscle fiber atrophy (HP:0100295) | 3.22763662 |
| 39 | Abnormality of the foot musculature (HP:0001436) | 3.17751513 |
| 40 | Action tremor (HP:0002345) | 3.13867965 |
| 41 | Abnormality of skeletal muscle fiber size (HP:0012084) | 3.12994452 |
| 42 | Difficulty climbing stairs (HP:0003551) | 3.11894586 |
| 43 | Popliteal pterygium (HP:0009756) | 3.10086650 |
| 44 | Pheochromocytoma (HP:0002666) | 3.09886999 |
| 45 | Impaired pain sensation (HP:0007328) | 3.08459317 |
| 46 | Abnormality of pain sensation (HP:0010832) | 3.08459317 |
| 47 | Increased variability in muscle fiber diameter (HP:0003557) | 3.01743227 |
| 48 | Abnormality of the calf musculature (HP:0001430) | 2.98165918 |
| 49 | Hammertoe (HP:0001765) | 2.85693512 |
| 50 | Gowers sign (HP:0003391) | 2.81697033 |
| 51 | Neuroendocrine neoplasm (HP:0100634) | 2.78171544 |
| 52 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 2.73203096 |
| 53 | EMG: neuropathic changes (HP:0003445) | 2.70717449 |
| 54 | Distal lower limb muscle weakness (HP:0009053) | 2.67396869 |
| 55 | Generalized muscle weakness (HP:0003324) | 2.66486340 |
| 56 | Ankle clonus (HP:0011448) | 2.65422288 |
| 57 | Frequent falls (HP:0002359) | 2.59371225 |
| 58 | Bulbar palsy (HP:0001283) | 2.55681142 |
| 59 | Onion bulb formation (HP:0003383) | 2.55220719 |
| 60 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.53060286 |
| 61 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.53060286 |
| 62 | Shoulder girdle muscle weakness (HP:0003547) | 2.52178751 |
| 63 | Impaired proprioception (HP:0010831) | 2.50562909 |
| 64 | Asymmetric septal hypertrophy (HP:0001670) | 2.50456560 |
| 65 | Hip contracture (HP:0003273) | 2.48231556 |
| 66 | Pelvic girdle muscle weakness (HP:0003749) | 2.47497357 |
| 67 | Abnormality of placental membranes (HP:0011409) | 2.45801820 |
| 68 | Amniotic constriction ring (HP:0009775) | 2.45801820 |
| 69 | Urinary urgency (HP:0000012) | 2.45471763 |
| 70 | Malignant hyperthermia (HP:0002047) | 2.43679156 |
| 71 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.43612902 |
| 72 | Subaortic stenosis (HP:0001682) | 2.43612902 |
| 73 | Rimmed vacuoles (HP:0003805) | 2.40591565 |
| 74 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.37907432 |
| 75 | Abnormality of the vocal cords (HP:0008777) | 2.32440186 |
| 76 | Nonprogressive disorder (HP:0003680) | 2.32400595 |
| 77 | Distal lower limb amyotrophy (HP:0008944) | 2.30640213 |
| 78 | Myokymia (HP:0002411) | 2.30308528 |
| 79 | Sudden death (HP:0001699) | 2.23782705 |
| 80 | Hyperkalemia (HP:0002153) | 2.22133796 |
| 81 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.21237883 |
| 82 | Adducted thumb (HP:0001181) | 2.19430977 |
| 83 | Neck muscle weakness (HP:0000467) | 2.18966482 |
| 84 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.18767449 |
| 85 | Easy fatigability (HP:0003388) | 2.10236005 |
| 86 | Lipoatrophy (HP:0100578) | 2.09571276 |
| 87 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.02953925 |
| 88 | Abnormality of the calcaneus (HP:0008364) | 2.02933974 |
| 89 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 2.01933421 |
| 90 | Muscular dystrophy (HP:0003560) | 2.01665846 |
| 91 | Dilated cardiomyopathy (HP:0001644) | 2.00723271 |
| 92 | Hypoglycemic coma (HP:0001325) | 1.98221941 |
| 93 | Heart block (HP:0012722) | 1.97245609 |
| 94 | Scapular winging (HP:0003691) | 1.96535485 |
| 95 | Atonic seizures (HP:0010819) | 1.93952635 |
| 96 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.93618974 |
| 97 | Slender build (HP:0001533) | 1.92898578 |
| 98 | Lower limb amyotrophy (HP:0007210) | 1.92867475 |
| 99 | Supranuclear gaze palsy (HP:0000605) | 1.91704760 |
| 100 | Proximal amyotrophy (HP:0007126) | 1.90842556 |
| 101 | Distal sensory impairment (HP:0002936) | 1.90454987 |
| 102 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.90216149 |
| 103 | Paralysis (HP:0003470) | 1.89620896 |
| 104 | Decreased motor nerve conduction velocity (HP:0003431) | 1.88198828 |
| 105 | Waddling gait (HP:0002515) | 1.85084762 |
| 106 | Postural tremor (HP:0002174) | 1.85025028 |
| 107 | Achilles tendon contracture (HP:0001771) | 1.80909346 |
| 108 | Ventricular fibrillation (HP:0001663) | 1.80843489 |
| 109 | Abnormal atrioventricular conduction (HP:0005150) | 1.80610556 |
| 110 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.79137232 |
| 111 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.78415857 |
| 112 | Spinal rigidity (HP:0003306) | 1.77961350 |
| 113 | Acute necrotizing encephalopathy (HP:0006965) | 1.75503988 |
| 114 | Exercise intolerance (HP:0003546) | 1.74376217 |
| 115 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.74105540 |
| 116 | Oligomenorrhea (HP:0000876) | 1.73969872 |
| 117 | Abnormality of the neuromuscular junction (HP:0003398) | 1.73113645 |
| 118 | Fatigable weakness (HP:0003473) | 1.73113645 |
| 119 | Rapidly progressive (HP:0003678) | 1.71451895 |
| 120 | Bundle branch block (HP:0011710) | 1.71447096 |
| 121 | Lower limb muscle weakness (HP:0007340) | 1.69120416 |
| 122 | Focal seizures (HP:0007359) | 1.68711530 |
| 123 | Ulnar deviation of finger (HP:0009465) | 1.68225086 |
| 124 | Hypercortisolism (HP:0001578) | 1.66012760 |
| 125 | Cholelithiasis (HP:0001081) | 1.65201171 |
| 126 | Visual hallucinations (HP:0002367) | 1.65114752 |
| 127 | Enlarged penis (HP:0000040) | 1.64899247 |
| 128 | Increased CSF protein (HP:0002922) | 1.64885753 |
| 129 | Failure to thrive in infancy (HP:0001531) | 1.64556100 |
| 130 | Focal motor seizures (HP:0011153) | 1.64391833 |
| 131 | Abnormality of the Achilles tendon (HP:0005109) | 1.64329807 |
| 132 | Palpitations (HP:0001962) | 1.63336939 |
| 133 | Stridor (HP:0010307) | 1.63062372 |
| 134 | Ketoacidosis (HP:0001993) | 1.62960511 |
| 135 | Limb-girdle muscle weakness (HP:0003325) | 1.62761074 |
| 136 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.62723375 |
| 137 | Limited hip movement (HP:0008800) | 1.61849650 |
| 138 | Short middle phalanx of the 5th finger (HP:0004220) | 1.61706387 |
| 139 | Limb-girdle muscle atrophy (HP:0003797) | 1.61328598 |
| 140 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.59616904 |
| 141 | Ulnar deviation of the hand or of fingers of the hand (HP:0001193) | 1.56482860 |
| 142 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.55853493 |
| 143 | Acute encephalopathy (HP:0006846) | 1.54734421 |
| 144 | Progressive macrocephaly (HP:0004481) | 1.52482852 |
| 145 | Long clavicles (HP:0000890) | 1.51976626 |
| 146 | Aplasia of the musculature (HP:0100854) | 1.51785699 |
| 147 | Wrist flexion contracture (HP:0001239) | 1.51683737 |
| 148 | Hypoglycemic seizures (HP:0002173) | 1.50527311 |
| 149 | Increased intramyocellular lipid droplets (HP:0012240) | 1.49235804 |
| 150 | Metatarsus adductus (HP:0001840) | 1.48248700 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | INSRR | 5.93619205 |
| 2 | PHKG1 | 5.20191078 |
| 3 | PHKG2 | 5.20191078 |
| 4 | OBSCN | 4.13753468 |
| 5 | KSR2 | 3.91414118 |
| 6 | TTN | 3.45924638 |
| 7 | NTRK1 | 3.18606183 |
| 8 | LMTK2 | 3.10035274 |
| 9 | MAP3K2 | 2.86957267 |
| 10 | MAP3K9 | 2.80004948 |
| 11 | LIMK1 | 2.66187608 |
| 12 | NME1 | 2.57479011 |
| 13 | AKT3 | 2.34689109 |
| 14 | RIPK4 | 2.19912119 |
| 15 | MAP2K4 | 2.05686638 |
| 16 | PINK1 | 2.01658598 |
| 17 | NEK1 | 2.01187039 |
| 18 | RET | 1.98686350 |
| 19 | MINK1 | 1.89237291 |
| 20 | NTRK3 | 1.84061109 |
| 21 | MATK | 1.79821767 |
| 22 | MAP2K3 | 1.72799756 |
| 23 | LATS2 | 1.72426344 |
| 24 | PIK3CG | 1.49887813 |
| 25 | MAP3K1 | 1.44293351 |
| 26 | GRK5 | 1.35998126 |
| 27 | MAP2K6 | 1.30555011 |
| 28 | PDK4 | 1.29125214 |
| 29 | PDK3 | 1.29125214 |
| 30 | ARAF | 1.26543993 |
| 31 | MOS | 1.24439892 |
| 32 | MARK1 | 1.21910184 |
| 33 | MAP3K7 | 1.21676656 |
| 34 | PAK6 | 1.21658961 |
| 35 | TIE1 | 1.21585537 |
| 36 | TRIB3 | 1.19355498 |
| 37 | MAP3K12 | 1.16577874 |
| 38 | MARK3 | 1.15601052 |
| 39 | MAP2K1 | 1.13982520 |
| 40 | MAP4K2 | 1.12746925 |
| 41 | MAP2K2 | 1.11922772 |
| 42 | MAPKAPK3 | 1.06755693 |
| 43 | PIK3CA | 1.06111444 |
| 44 | NEK9 | 1.01322813 |
| 45 | EPHA3 | 0.98777077 |
| 46 | BMPR1B | 0.96123431 |
| 47 | RPS6KA2 | 0.92419294 |
| 48 | MAPK12 | 0.89800707 |
| 49 | WNK1 | 0.89228889 |
| 50 | AKT2 | 0.85844681 |
| 51 | MAP3K4 | 0.84002270 |
| 52 | EPHB1 | 0.79763723 |
| 53 | ERBB3 | 0.77497069 |
| 54 | BRAF | 0.75829260 |
| 55 | IRAK3 | 0.74244792 |
| 56 | ADRBK2 | 0.69488752 |
| 57 | CCNB1 | 0.68364866 |
| 58 | FER | 0.66984588 |
| 59 | PKN1 | 0.66983452 |
| 60 | CAMK2D | 0.63655780 |
| 61 | TLK1 | 0.63151671 |
| 62 | SCYL2 | 0.62605978 |
| 63 | PRKAA1 | 0.62424774 |
| 64 | PRKD3 | 0.62100726 |
| 65 | DYRK1B | 0.61315867 |
| 66 | SGK223 | 0.60284563 |
| 67 | SGK494 | 0.60284563 |
| 68 | MAP3K11 | 0.59947411 |
| 69 | PDK2 | 0.59903108 |
| 70 | PDK1 | 0.59681520 |
| 71 | STK39 | 0.56848679 |
| 72 | PLK2 | 0.56837456 |
| 73 | PRKG2 | 0.56696682 |
| 74 | TRPM7 | 0.54957059 |
| 75 | FGFR3 | 0.51997739 |
| 76 | CAMK1 | 0.51912054 |
| 77 | PDPK1 | 0.51467412 |
| 78 | STK11 | 0.50431640 |
| 79 | PRKG1 | 0.50081399 |
| 80 | CAMK2B | 0.48295061 |
| 81 | PKN2 | 0.47810358 |
| 82 | CDK5 | 0.47078936 |
| 83 | BCKDK | 0.46790334 |
| 84 | DAPK2 | 0.43754538 |
| 85 | ABL2 | 0.43707991 |
| 86 | STK24 | 0.42872596 |
| 87 | CAMK2G | 0.42276149 |
| 88 | MAPK7 | 0.42214155 |
| 89 | OXSR1 | 0.41535963 |
| 90 | DMPK | 0.41465197 |
| 91 | WNK3 | 0.40951096 |
| 92 | EPHB2 | 0.38974320 |
| 93 | PTK2B | 0.38949677 |
| 94 | MAPK13 | 0.38650046 |
| 95 | ROCK1 | 0.38519644 |
| 96 | SGK3 | 0.37908746 |
| 97 | WNK4 | 0.37311590 |
| 98 | CAMK4 | 0.35800504 |
| 99 | JAK2 | 0.35142046 |
| 100 | MAP2K7 | 0.35076153 |
| 101 | LRRK2 | 0.34581713 |
| 102 | ADRBK1 | 0.34272042 |
| 103 | PRKAA2 | 0.33793336 |
| 104 | PRKACB | 0.33171242 |
| 105 | CDK14 | 0.33065651 |
| 106 | RIPK1 | 0.31947927 |
| 107 | GRK1 | 0.31534892 |
| 108 | PRKACA | 0.30470355 |
| 109 | SGK2 | 0.29629072 |
| 110 | PTK2 | 0.28365436 |
| 111 | FRK | 0.28285904 |
| 112 | MAPK10 | 0.27781967 |
| 113 | CAMKK1 | 0.26420165 |
| 114 | PRKCG | 0.25945118 |
| 115 | RPS6KA5 | 0.25415176 |
| 116 | TGFBR1 | 0.25109663 |
| 117 | CDC42BPA | 0.24802549 |
| 118 | MAPK4 | 0.24464812 |
| 119 | FLT3 | 0.24272925 |
| 120 | DYRK1A | 0.23863799 |
| 121 | RAF1 | 0.23698707 |
| 122 | STK16 | 0.22238213 |
| 123 | STK38 | 0.21606291 |
| 124 | RPS6KA3 | 0.20884762 |
| 125 | TAOK1 | 0.20662894 |
| 126 | ACVR1B | 0.20347052 |
| 127 | SGK1 | 0.20297998 |
| 128 | MUSK | 0.19849474 |
| 129 | PRKCZ | 0.19433152 |
| 130 | ROCK2 | 0.18980797 |
| 131 | ILK | 0.18312368 |
| 132 | KSR1 | 0.17838423 |
| 133 | FGFR4 | 0.17764533 |
| 134 | PRKACG | 0.17600233 |
| 135 | CDK19 | 0.17582656 |
| 136 | MAPK11 | 0.17019366 |
| 137 | DYRK3 | 0.16892736 |
| 138 | CSNK1D | 0.16287287 |
| 139 | PAK3 | 0.15431298 |
| 140 | CAMK2A | 0.15280794 |
| 141 | EIF2AK3 | 0.15015844 |
| 142 | UHMK1 | 0.14956415 |
| 143 | CAMKK2 | 0.14771119 |
| 144 | CSNK1G2 | 0.12280629 |
| 145 | CSNK1A1 | 0.12170439 |
| 146 | PRKCA | 0.11897721 |
| 147 | LATS1 | 0.08403551 |
| 148 | PRKCQ | 0.07867201 |
| 149 | NUAK1 | 0.07844849 |
| 150 | DYRK2 | 0.07392703 |
| 151 | RPS6KB1 | 0.06477638 |
| 152 | RPS6KA6 | 0.06423342 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.70129213 |
| 2 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.41928381 |
| 3 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.37422387 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.34713365 |
| 5 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 2.25721681 |
| 6 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 2.21330502 |
| 7 | Insulin signaling pathway_Homo sapiens_hsa04910 | 2.07284234 |
| 8 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 2.05393015 |
| 9 | Thyroid cancer_Homo sapiens_hsa05216 | 2.01581363 |
| 10 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.00089188 |
| 11 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.97301711 |
| 12 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.84063913 |
| 13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.82279214 |
| 14 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.81952905 |
| 15 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.81533631 |
| 16 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.79003027 |
| 17 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.75755114 |
| 18 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.73172827 |
| 19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.69132076 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.66525685 |
| 21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.61607009 |
| 22 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.58789486 |
| 23 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.58100157 |
| 24 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.56523080 |
| 25 | Insulin secretion_Homo sapiens_hsa04911 | 1.56058600 |
| 26 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.56037263 |
| 27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.55608567 |
| 28 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.49880084 |
| 29 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.42042973 |
| 30 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.40515656 |
| 31 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.38557159 |
| 32 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.34365923 |
| 33 | Insulin resistance_Homo sapiens_hsa04931 | 1.33789380 |
| 34 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.32870994 |
| 35 | Long-term potentiation_Homo sapiens_hsa04720 | 1.30769802 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.28311063 |
| 37 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.27356196 |
| 38 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.26905984 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.25470707 |
| 40 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.23126784 |
| 41 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.20680093 |
| 42 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.20235017 |
| 43 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.18861268 |
| 44 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.17661865 |
| 45 | Glioma_Homo sapiens_hsa05214 | 1.16028656 |
| 46 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.14653839 |
| 47 | Circadian rhythm_Homo sapiens_hsa04710 | 1.11717436 |
| 48 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.09091126 |
| 49 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.08859355 |
| 50 | Phototransduction_Homo sapiens_hsa04744 | 1.07806835 |
| 51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.06907359 |
| 52 | Long-term depression_Homo sapiens_hsa04730 | 1.04298029 |
| 53 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.02686770 |
| 54 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.02028352 |
| 55 | Circadian entrainment_Homo sapiens_hsa04713 | 0.98842808 |
| 56 | Alzheimers disease_Homo sapiens_hsa05010 | 0.97446816 |
| 57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.95873130 |
| 58 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.95803715 |
| 59 | Salmonella infection_Homo sapiens_hsa05132 | 0.93988119 |
| 60 | Parkinsons disease_Homo sapiens_hsa05012 | 0.92651266 |
| 61 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.92064736 |
| 62 | Salivary secretion_Homo sapiens_hsa04970 | 0.92034135 |
| 63 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.90990149 |
| 64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89879758 |
| 65 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87367097 |
| 66 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.87349927 |
| 67 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.87143686 |
| 68 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.84559081 |
| 69 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.83974337 |
| 70 | Gap junction_Homo sapiens_hsa04540 | 0.83621372 |
| 71 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.83553073 |
| 72 | Tight junction_Homo sapiens_hsa04530 | 0.82864599 |
| 73 | Renin secretion_Homo sapiens_hsa04924 | 0.80813925 |
| 74 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.79976038 |
| 75 | Endometrial cancer_Homo sapiens_hsa05213 | 0.79687129 |
| 76 | Taste transduction_Homo sapiens_hsa04742 | 0.78597255 |
| 77 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.77882807 |
| 78 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.77153091 |
| 79 | Peroxisome_Homo sapiens_hsa04146 | 0.75279105 |
| 80 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.74552024 |
| 81 | Melanogenesis_Homo sapiens_hsa04916 | 0.74001329 |
| 82 | Melanoma_Homo sapiens_hsa05218 | 0.72397146 |
| 83 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.72057167 |
| 84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71007812 |
| 85 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.70964031 |
| 86 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.70776991 |
| 87 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.70592576 |
| 88 | Carbon metabolism_Homo sapiens_hsa01200 | 0.70366081 |
| 89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.69867251 |
| 90 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.69479002 |
| 91 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.69312170 |
| 92 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.69303156 |
| 93 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.69080698 |
| 94 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.68067780 |
| 95 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.67101076 |
| 96 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.66951308 |
| 97 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66932345 |
| 98 | Viral myocarditis_Homo sapiens_hsa05416 | 0.66859578 |
| 99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.65813073 |
| 100 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.65691178 |
| 101 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.64801413 |
| 102 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.64143419 |
| 103 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.63447704 |
| 104 | Ribosome_Homo sapiens_hsa03010 | 0.60603730 |
| 105 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.59787815 |
| 106 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.58976957 |
| 107 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.58620733 |
| 108 | Bile secretion_Homo sapiens_hsa04976 | 0.58330631 |
| 109 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.57804540 |
| 110 | Galactose metabolism_Homo sapiens_hsa00052 | 0.57024232 |
| 111 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.56521707 |
| 112 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.56347110 |
| 113 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.56346728 |
| 114 | Mineral absorption_Homo sapiens_hsa04978 | 0.55658638 |
| 115 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.55479787 |
| 116 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.54643804 |
| 117 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.53109318 |
| 118 | Platelet activation_Homo sapiens_hsa04611 | 0.52718958 |
| 119 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.52638628 |
| 120 | GABAergic synapse_Homo sapiens_hsa04727 | 0.51614328 |
| 121 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.51331449 |
| 122 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51235850 |
| 123 | Endocytosis_Homo sapiens_hsa04144 | 0.50994018 |
| 124 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.50423464 |
| 125 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.49562399 |
| 126 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.49223026 |
| 127 | Amoebiasis_Homo sapiens_hsa05146 | 0.47959637 |
| 128 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.47363557 |
| 129 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.46140831 |
| 130 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.45335457 |
| 131 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44770784 |
| 132 | Focal adhesion_Homo sapiens_hsa04510 | 0.43774207 |
| 133 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.43432955 |
| 134 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.42809973 |
| 135 | Histidine metabolism_Homo sapiens_hsa00340 | 0.42656118 |
| 136 | Proteasome_Homo sapiens_hsa03050 | 0.39420836 |
| 137 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39086697 |
| 138 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.33076037 |
| 139 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.29001202 |
| 140 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.27591953 |
| 141 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26764271 |
| 142 | RNA polymerase_Homo sapiens_hsa03020 | 0.25622278 |
| 143 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.24865346 |
| 144 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.24596801 |
| 145 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.24113898 |
| 146 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.23303458 |

