TMEM242

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.36456615
2tricarboxylic acid cycle (GO:0006099)5.35764078
3establishment of protein localization to mitochondrial membrane (GO:0090151)5.27534900
4energy coupled proton transport, down electrochemical gradient (GO:0015985)5.12019139
5ATP synthesis coupled proton transport (GO:0015986)5.12019139
6protein neddylation (GO:0045116)4.81706968
7oxidative phosphorylation (GO:0006119)4.77033147
8proteasome assembly (GO:0043248)4.53516173
9respiratory electron transport chain (GO:0022904)4.43300735
10electron transport chain (GO:0022900)4.33458765
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.30120397
12ribosomal small subunit assembly (GO:0000028)4.24597328
13lysine catabolic process (GO:0006554)4.16765295
14lysine metabolic process (GO:0006553)4.16765295
15respiratory chain complex IV assembly (GO:0008535)4.11414214
16branched-chain amino acid catabolic process (GO:0009083)4.03251463
17NADH metabolic process (GO:0006734)4.02777166
18cullin deneddylation (GO:0010388)3.75528047
19nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.74062804
20valine metabolic process (GO:0006573)3.73703994
21tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.71441346
22RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.71441346
23cytochrome complex assembly (GO:0017004)3.70610328
24fatty acid beta-oxidation (GO:0006635)3.69881324
25viral transcription (GO:0019083)3.68273317
26branched-chain amino acid metabolic process (GO:0009081)3.65037611
27exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.61041273
28sarcomere organization (GO:0045214)3.58265046
292-oxoglutarate metabolic process (GO:0006103)3.58064830
30erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.57808718
31L-phenylalanine metabolic process (GO:0006558)3.57808718
32translational termination (GO:0006415)3.57107771
33aspartate family amino acid catabolic process (GO:0009068)3.52411999
34tricarboxylic acid metabolic process (GO:0072350)3.52407558
35oxaloacetate metabolic process (GO:0006107)3.52371513
36translational elongation (GO:0006414)3.49790597
37actin-myosin filament sliding (GO:0033275)3.47958845
38muscle filament sliding (GO:0030049)3.47958845
39transcription elongation from RNA polymerase III promoter (GO:0006385)3.47725451
40termination of RNA polymerase III transcription (GO:0006386)3.47725451
41SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.47421203
42protein deneddylation (GO:0000338)3.45914689
43regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.43016745
44hydrogen ion transmembrane transport (GO:1902600)3.42434215
45DNA deamination (GO:0045006)3.39915662
46succinate metabolic process (GO:0006105)3.39747703
47rRNA modification (GO:0000154)3.37936266
48glyoxylate metabolic process (GO:0046487)3.37933996
49protein targeting to ER (GO:0045047)3.37792197
50cotranslational protein targeting to membrane (GO:0006613)3.37749052
51protein targeting to mitochondrion (GO:0006626)3.28528667
52fatty acid catabolic process (GO:0009062)3.22921941
53acetyl-CoA metabolic process (GO:0006084)3.22120638
54Golgi transport vesicle coating (GO:0048200)3.21887610
55COPI coating of Golgi vesicle (GO:0048205)3.21887610
56establishment of protein localization to endoplasmic reticulum (GO:0072599)3.21102762
57protein localization to endoplasmic reticulum (GO:0070972)3.21010571
58regulation of coenzyme metabolic process (GO:0051196)3.15658413
59regulation of cofactor metabolic process (GO:0051193)3.15658413
60L-phenylalanine catabolic process (GO:0006559)3.15273425
61erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.15273425
62carnitine shuttle (GO:0006853)3.15203865
63establishment of protein localization to mitochondrion (GO:0072655)3.15095341
64behavioral response to nicotine (GO:0035095)3.13983317
65water-soluble vitamin biosynthetic process (GO:0042364)3.13381770
66quinone biosynthetic process (GO:1901663)3.12129817
67ubiquinone biosynthetic process (GO:0006744)3.12129817
68DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.12059512
69proton transport (GO:0015992)3.10799977
70ATP biosynthetic process (GO:0006754)3.08250345
71fatty acid oxidation (GO:0019395)3.08090493
72hydrogen transport (GO:0006818)3.06916153
73protein localization to mitochondrion (GO:0070585)3.06513246
74regulation of mitochondrial translation (GO:0070129)3.06099545
75fatty acid transmembrane transport (GO:1902001)3.03864210
76intracellular protein transmembrane import (GO:0044743)3.03752164
77ribonucleoside triphosphate biosynthetic process (GO:0009201)3.03391922
78regulation of acyl-CoA biosynthetic process (GO:0050812)3.03253319
79signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.01165012
80signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.01165012
81signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.01165012
82signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.00819470
83intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.00819470
84lipid oxidation (GO:0034440)2.99363891
854-hydroxyproline metabolic process (GO:0019471)2.99187644
86aldehyde catabolic process (GO:0046185)2.97716505
87pseudouridine synthesis (GO:0001522)2.97648727
88negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.97593659
89platelet dense granule organization (GO:0060155)2.96372163
90chaperone-mediated protein transport (GO:0072321)2.96003413
91maturation of SSU-rRNA (GO:0030490)2.95198061
92short-chain fatty acid metabolic process (GO:0046459)2.94849214
93protein-cofactor linkage (GO:0018065)2.93839314
94mannosylation (GO:0097502)2.91248203
95translation (GO:0006412)2.91114548
96translational initiation (GO:0006413)2.89132558
97maturation of 5.8S rRNA (GO:0000460)2.88472976
98regulation of oxidative phosphorylation (GO:0002082)2.88374557
99anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.87541100
100positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.87196269
101signal transduction involved in DNA damage checkpoint (GO:0072422)2.85540490
102signal transduction involved in DNA integrity checkpoint (GO:0072401)2.85540490
103heart process (GO:0003015)2.85217840
104heart contraction (GO:0060047)2.85217840
105cellular component biogenesis (GO:0044085)2.85025649
106nucleoside triphosphate biosynthetic process (GO:0009142)2.84950598
107GTP biosynthetic process (GO:0006183)2.84810683
108signal transduction involved in cell cycle checkpoint (GO:0072395)2.83964001
109aerobic respiration (GO:0009060)2.83855427
110purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.83791809
111purine nucleoside monophosphate biosynthetic process (GO:0009127)2.83791809
112ubiquinone metabolic process (GO:0006743)2.83420128
113deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.83310536
114monocarboxylic acid catabolic process (GO:0072329)2.83093679
115mitochondrial respiratory chain complex I assembly (GO:0032981)2.81168710
116NADH dehydrogenase complex assembly (GO:0010257)2.81168710
117mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.81168710
118mitochondrial transport (GO:0006839)2.80691567
119viral life cycle (GO:0019058)2.79885966
120purine nucleoside triphosphate biosynthetic process (GO:0009145)2.79704900
121ribosomal small subunit biogenesis (GO:0042274)2.79469637
122peptidyl-histidine modification (GO:0018202)2.79060377
123glycine metabolic process (GO:0006544)2.78439023
124protein complex biogenesis (GO:0070271)2.78327235
125positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.77412261
126organelle disassembly (GO:1903008)2.77318304
127nucleoside diphosphate biosynthetic process (GO:0009133)2.76681169
128formation of translation preinitiation complex (GO:0001731)2.75273517
129mitochondrial respiratory chain complex assembly (GO:0033108)2.75200333
130alpha-linolenic acid metabolic process (GO:0036109)2.74432721
131purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.74291629
132regulation of cellular amino acid metabolic process (GO:0006521)2.73779095
133cellular protein complex disassembly (GO:0043624)2.73646086
134ribosomal large subunit biogenesis (GO:0042273)2.72507183
135DNA damage response, detection of DNA damage (GO:0042769)2.71653530
136negative regulation of ligase activity (GO:0051352)2.71251463
137negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.71251463
138positive regulation of ligase activity (GO:0051351)2.70527617
139pteridine-containing compound biosynthetic process (GO:0042559)2.69967304
140galactose catabolic process (GO:0019388)2.68201985
141regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.67007091
142inner mitochondrial membrane organization (GO:0007007)2.66695052
143biotin metabolic process (GO:0006768)2.66187131
144negative regulation of telomere maintenance (GO:0032205)2.65566104
145regulation of sequestering of triglyceride (GO:0010889)2.65102540
146serine family amino acid biosynthetic process (GO:0009070)2.64880268
147dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.63614020
148cellular ketone body metabolic process (GO:0046950)2.63572096
149purine nucleobase biosynthetic process (GO:0009113)2.62789007
150spliceosomal snRNP assembly (GO:0000387)2.62620755
151cysteine metabolic process (GO:0006534)2.62462640
152purine nucleotide salvage (GO:0032261)2.62028654
153ketone body metabolic process (GO:1902224)2.59913710
154purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.59558560

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.75613824
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.40936536
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.18719222
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.61534198
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.48154685
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.42754251
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.29199643
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.04989372
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.94113818
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.93193854
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.89373707
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.84694112
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.78371122
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.69661337
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.69647296
16ELK1_19687146_ChIP-ChIP_HELA_Human2.68504326
17MYC_18358816_ChIP-ChIP_MESCs_Mouse2.59041940
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.51636025
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.26559311
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.25406288
21E2F1_18555785_ChIP-Seq_MESCs_Mouse2.21095534
22XRN2_22483619_ChIP-Seq_HELA_Human2.20803673
23PPARA_22158963_ChIP-Seq_LIVER_Mouse2.17339722
24IGF1R_20145208_ChIP-Seq_DFB_Human2.16634121
25RXR_22158963_ChIP-Seq_LIVER_Mouse2.13836057
26ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.12432788
27MYC_19079543_ChIP-ChIP_MESCs_Mouse2.10925770
28VDR_22108803_ChIP-Seq_LS180_Human2.08402398
29ZNF274_21170338_ChIP-Seq_K562_Hela2.08382888
30PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.05850426
31SRF_21415370_ChIP-Seq_HL-1_Mouse2.02693653
32FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.00797202
33CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.98867508
34CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.97855731
35DCP1A_22483619_ChIP-Seq_HELA_Human1.96849325
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.91657808
37EWS_26573619_Chip-Seq_HEK293_Human1.88673233
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.88490795
39FUS_26573619_Chip-Seq_HEK293_Human1.85031383
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.82720662
41ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79754654
42RARG_19884340_ChIP-ChIP_MEFs_Mouse1.79586351
43CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.77199844
44HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.76839502
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.75760914
46CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.74376914
47FLI1_27457419_Chip-Seq_LIVER_Mouse1.74040397
48GABP_19822575_ChIP-Seq_HepG2_Human1.74035703
49BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.73976238
50TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72087748
51MYC_18940864_ChIP-ChIP_HL60_Human1.71791246
52SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.63725359
53VDR_23849224_ChIP-Seq_CD4+_Human1.60904413
54HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.60015362
55ZNF263_19887448_ChIP-Seq_K562_Human1.59590007
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.58926988
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58480906
58YY1_21170310_ChIP-Seq_MESCs_Mouse1.55715432
59ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52065050
60NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.50390128
61FOXP3_21729870_ChIP-Seq_TREG_Human1.49098366
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48725543
63TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48309350
64TAF15_26573619_Chip-Seq_HEK293_Human1.48054813
65PADI4_21655091_ChIP-ChIP_MCF-7_Human1.45394225
66CLOCK_20551151_ChIP-Seq_293T_Human1.44886381
67P300_19829295_ChIP-Seq_ESCs_Human1.43726042
68GBX2_23144817_ChIP-Seq_PC3_Human1.42849373
69CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.41677337
70E2F4_17652178_ChIP-ChIP_JURKAT_Human1.40814560
71STAT3_1855785_ChIP-Seq_MESCs_Mouse1.39715302
72TTF2_22483619_ChIP-Seq_HELA_Human1.38295287
73FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.32960441
74ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.32424324
75PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32381167
76DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.31303008
77CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.30058802
78NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.29865848
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28720695
80GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28077688
81CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27921718
82TP53_22573176_ChIP-Seq_HFKS_Human1.27426162
83LXR_22158963_ChIP-Seq_LIVER_Mouse1.27264526
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25815427
85MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.25058578
86HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.22817368
87POU5F1_16153702_ChIP-ChIP_HESCs_Human1.22480603
88CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21165778
89AR_21909140_ChIP-Seq_LNCAP_Human1.20587212
90CIITA_25753668_ChIP-Seq_RAJI_Human1.19816137
91FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18107562
92ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18105496
93CTCF_18555785_ChIP-Seq_MESCs_Mouse1.18080362
94* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.16788927
95EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.16433798
96TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16239703
97POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.16124931
98MYCN_18555785_ChIP-Seq_MESCs_Mouse1.14996685
99TBX5_21415370_ChIP-Seq_HL-1_Mouse1.13854628
100NANOG_18555785_ChIP-Seq_MESCs_Mouse1.13557556
101FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.11978922
102SOX2_19829295_ChIP-Seq_ESCs_Human1.11672579
103NANOG_19829295_ChIP-Seq_ESCs_Human1.11672579
104SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.10363968
105DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.09599768
106HOXB4_20404135_ChIP-ChIP_EML_Mouse1.09539587
107KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09236534
108EZH2_27294783_Chip-Seq_NPCs_Mouse1.08586363
109HTT_18923047_ChIP-ChIP_STHdh_Human1.08475464
110ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07790279
111TET1_21451524_ChIP-Seq_MESCs_Mouse1.06425394
112MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.05929025
113FOXP1_21924763_ChIP-Seq_HESCs_Human1.05282502
114SOX2_18692474_ChIP-Seq_MEFs_Mouse1.05078742
115NFE2_27457419_Chip-Seq_LIVER_Mouse1.02733273
116SUZ12_27294783_Chip-Seq_NPCs_Mouse1.02532527
117KDM5A_27292631_Chip-Seq_BREAST_Human1.02273270
118GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01365296
119KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01162709
120OCT4_18692474_ChIP-Seq_MEFs_Mouse1.00913091
121SOX2_16153702_ChIP-ChIP_HESCs_Human1.00001189
122BMI1_23680149_ChIP-Seq_NPCS_Mouse0.99677835
123SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.99405294
124FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98922995
125RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98527846
126TFEB_21752829_ChIP-Seq_HELA_Human0.98168661
127YY1_22570637_ChIP-Seq_MALME-3M_Human0.98136424
128ELK1_22589737_ChIP-Seq_MCF10A_Human0.98073414
129YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.97602825
130GATA4_21415370_ChIP-Seq_HL-1_Mouse0.97125094
131EZH2_22144423_ChIP-Seq_EOC_Human0.96714438
132EGR1_23403033_ChIP-Seq_LIVER_Mouse0.96488793
133RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.96437834
134KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96028567
135E2F7_22180533_ChIP-Seq_HELA_Human0.95899689
136ER_23166858_ChIP-Seq_MCF-7_Human0.95500894
137TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94703036
138FOXM1_23109430_ChIP-Seq_U2OS_Human0.94343116
139KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93431124
140POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92897993
141NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.92391994
142PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.91742423
143SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91154281
144RNF2_27304074_Chip-Seq_NSC_Mouse0.90902721
145AR_20517297_ChIP-Seq_VCAP_Human0.90691144
146CRX_20693478_ChIP-Seq_RETINA_Mouse0.89763017
147UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89544027
148NANOG_21062744_ChIP-ChIP_HESCs_Human0.89364694
149MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.88725599
150TOP2B_26459242_ChIP-Seq_MCF-7_Human0.87925403
151NANOG_16153702_ChIP-ChIP_HESCs_Human0.87423683
152CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.87155832
153GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.86484207
154SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85796322
155SMAD4_21799915_ChIP-Seq_A2780_Human0.85686158
156IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84753283
157CBP_20019798_ChIP-Seq_JUKART_Human0.84753283
158P53_22387025_ChIP-Seq_ESCs_Mouse0.83558320
159FOXA1_27270436_Chip-Seq_PROSTATE_Human0.83362411
160FOXA1_25329375_ChIP-Seq_VCAP_Human0.83362411

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis4.59375001
2MP0003806_abnormal_nucleotide_metabolis4.36199065
3MP0003646_muscle_fatigue3.50915386
4MP0004084_abnormal_cardiac_muscle3.33257920
5MP0002139_abnormal_hepatobiliary_system3.15245228
6MP0006036_abnormal_mitochondrial_physio3.14782507
7MP0005360_urolithiasis3.08760926
8MP0000749_muscle_degeneration3.06211369
9MP0006292_abnormal_olfactory_placode3.02799204
10MP0003880_abnormal_central_pattern2.98858531
11MP0000751_myopathy2.85214056
12MP0005083_abnormal_biliary_tract2.68521114
13MP0004036_abnormal_muscle_relaxation2.64011559
14MP0005365_abnormal_bile_salt2.61286496
15MP0005085_abnormal_gallbladder_physiolo2.59575865
16MP0001529_abnormal_vocalization2.50639823
17MP0008058_abnormal_DNA_repair2.50331726
18MP0002638_abnormal_pupillary_reflex2.41544455
19MP0005330_cardiomyopathy2.39625670
20MP0009840_abnormal_foam_cell2.25876799
21MP0004215_abnormal_myocardial_fiber2.22213569
22MP0000372_irregular_coat_pigmentation2.22133487
23MP0003186_abnormal_redox_activity2.19119391
24MP0000750_abnormal_muscle_regeneration2.14326533
25MP0009046_muscle_twitch2.13838086
26MP0002736_abnormal_nociception_after2.13278780
27MP0001984_abnormal_olfaction2.11646206
28MP0005332_abnormal_amino_acid2.06591094
29MP0003221_abnormal_cardiomyocyte_apopto2.06018055
30MP0002269_muscular_atrophy2.05416448
31MP0004087_abnormal_muscle_fiber2.00085718
32MP0004142_abnormal_muscle_tone1.97380544
33MP0003136_yellow_coat_color1.96288033
34MP0001968_abnormal_touch/_nociception1.96102563
35MP0005670_abnormal_white_adipose1.92582688
36MP0003705_abnormal_hypodermis_morpholog1.92266578
37MP0006035_abnormal_mitochondrial_morpho1.91477979
38MP0006072_abnormal_retinal_apoptosis1.91138451
39MP0006276_abnormal_autonomic_nervous1.88419672
40MP0002938_white_spotting1.80759355
41MP0002102_abnormal_ear_morphology1.77952761
42MP0008775_abnormal_heart_ventricle1.76524641
43MP0000747_muscle_weakness1.74153522
44MP0004130_abnormal_muscle_cell1.74084422
45MP0002972_abnormal_cardiac_muscle1.70913020
46MP0005646_abnormal_pituitary_gland1.69802237
47MP0002272_abnormal_nervous_system1.66278667
48MP0003122_maternal_imprinting1.63476219
49MP0008789_abnormal_olfactory_epithelium1.63003849
50MP0005620_abnormal_muscle_contractility1.62811185
51MP0003787_abnormal_imprinting1.61468021
52MP0008877_abnormal_DNA_methylation1.61453202
53MP0003718_maternal_effect1.60293853
54MP0002822_catalepsy1.59502216
55MP0009745_abnormal_behavioral_response1.57087747
56MP0005551_abnormal_eye_electrophysiolog1.55767031
57MP0002106_abnormal_muscle_physiology1.54920384
58MP0001905_abnormal_dopamine_level1.54083329
59MP0003195_calcinosis1.52647228
60MP0005385_cardiovascular_system_phenoty1.52398569
61MP0001544_abnormal_cardiovascular_syste1.52398569
62MP0010386_abnormal_urinary_bladder1.50924366
63MP0008438_abnormal_cutaneous_collagen1.49045180
64MP0003693_abnormal_embryo_hatching1.49022123
65MP0004145_abnormal_muscle_electrophysio1.48653092
66MP0010630_abnormal_cardiac_muscle1.47492009
67MP0004233_abnormal_muscle_weight1.45929083
68MP0000759_abnormal_skeletal_muscle1.45604663
69MP0001666_abnormal_nutrient_absorption1.44591581
70MP0005319_abnormal_enzyme/_coenzyme1.43943922
71MP0005253_abnormal_eye_physiology1.40859443
72MP0003121_genomic_imprinting1.40520013
73MP0005666_abnormal_adipose_tissue1.40432483
74MP0008875_abnormal_xenobiotic_pharmacok1.39159791
75MP0010329_abnormal_lipoprotein_level1.37602483
76MP0003252_abnormal_bile_duct1.34482334
77MP0009643_abnormal_urine_homeostasis1.33515379
78MP0008995_early_reproductive_senescence1.33252259
79MP0003786_premature_aging1.31304136
80MP0002734_abnormal_mechanical_nocicepti1.29433485
81MP0001486_abnormal_startle_reflex1.29349128
82MP0003011_delayed_dark_adaptation1.28657615
83MP0009379_abnormal_foot_pigmentation1.27735178
84MP0002928_abnormal_bile_duct1.27574601
85MP0004957_abnormal_blastocyst_morpholog1.25912778
86MP0000358_abnormal_cell_content/1.25595436
87MP0005084_abnormal_gallbladder_morpholo1.24745954
88MP0005369_muscle_phenotype1.24407603
89MP0003137_abnormal_impulse_conducting1.24198275
90MP0005584_abnormal_enzyme/coenzyme_acti1.24122275
91MP0005266_abnormal_metabolism1.23379311
92MP0000013_abnormal_adipose_tissue1.22794140
93MP0004147_increased_porphyrin_level1.22333175
94MP0002064_seizures1.21290375
95MP0001485_abnormal_pinna_reflex1.19710729
96MP0003567_abnormal_fetal_cardiomyocyte1.18283056
97MP0002090_abnormal_vision1.16419989
98MP0001293_anophthalmia1.16341151
99MP0001756_abnormal_urination1.15969988
100MP0005394_taste/olfaction_phenotype1.15483602
101MP0005499_abnormal_olfactory_system1.15483602
102MP0002163_abnormal_gland_morphology1.14431563
103MP0006138_congestive_heart_failure1.13672908
104MP0008872_abnormal_physiological_respon1.13485565
105MP0010030_abnormal_orbit_morphology1.11819035
106MP0002572_abnormal_emotion/affect_behav1.11233809
107MP0000631_abnormal_neuroendocrine_gland1.10701990
108MP0003635_abnormal_synaptic_transmissio1.09300068
109MP0002118_abnormal_lipid_homeostasis1.05190774
110MP0001986_abnormal_taste_sensitivity1.01883551
111MP0002067_abnormal_sensory_capabilities1.01538198
112MP0003279_aneurysm1.00822626
113MP0002735_abnormal_chemical_nociception1.00636137
114MP0003656_abnormal_erythrocyte_physiolo1.00328617
115MP0009697_abnormal_copulation0.98136788
116MP0002557_abnormal_social/conspecific_i0.96908278
117MP0001764_abnormal_homeostasis0.96548942
118MP0001970_abnormal_pain_threshold0.95564970
119MP0002160_abnormal_reproductive_system0.95130661
120MP0000609_abnormal_liver_physiology0.94447808
121MP0005220_abnormal_exocrine_pancreas0.94046450
122MP0002277_abnormal_respiratory_mucosa0.93151278
123MP0005636_abnormal_mineral_homeostasis0.92479383
124MP0001188_hyperpigmentation0.92161551
125MP0002184_abnormal_innervation0.91646986
126MP0003123_paternal_imprinting0.91212765
127MP0005058_abnormal_lysosome_morphology0.91131527
128MP0004270_analgesia0.90887637
129MP0005375_adipose_tissue_phenotype0.90825965
130MP0004043_abnormal_pH_regulation0.90110774
131MP0005423_abnormal_somatic_nervous0.88750321
132MP0002127_abnormal_cardiovascular_syste0.88746518
133MP0002332_abnormal_exercise_endurance0.88413840
134MP0002653_abnormal_ependyma_morphology0.88314994
135MP0001730_embryonic_growth_arrest0.87343652
136MP0002234_abnormal_pharynx_morphology0.86957309
137MP0003959_abnormal_lean_body0.86046180
138MP0002078_abnormal_glucose_homeostasis0.85114608
139MP0002733_abnormal_thermal_nociception0.84126031
140MP0005187_abnormal_penis_morphology0.83842918
141MP0002095_abnormal_skin_pigmentation0.82258470
142MP0000778_abnormal_nervous_system0.81793532
143MP0005075_abnormal_melanosome_morpholog0.81029245
144MP0005389_reproductive_system_phenotype0.80318084
145MP0000230_abnormal_systemic_arterial0.80281266
146MP0002752_abnormal_somatic_nervous0.80191715
147MP0004885_abnormal_endolymph0.79359674
148MP0001440_abnormal_grooming_behavior0.79163235
149MP0002063_abnormal_learning/memory/cond0.79160687
150MP0003191_abnormal_cellular_cholesterol0.78985841
151MP0000647_abnormal_sebaceous_gland0.78356702
152MP0005645_abnormal_hypothalamus_physiol0.78058371
153MP0002751_abnormal_autonomic_nervous0.77699162
154MP0000598_abnormal_liver_morphology0.76420467
155MP0005379_endocrine/exocrine_gland_phen0.75186913
156MP0000516_abnormal_urinary_system0.75122639
157MP0005367_renal/urinary_system_phenotyp0.75122639
158MP0003283_abnormal_digestive_organ0.74633986
159MP0008932_abnormal_embryonic_tissue0.73899506
160MP0005408_hypopigmentation0.71763690
161MP0005376_homeostasis/metabolism_phenot0.70011701
162MP0000343_altered_response_to0.70004216
163MP0003077_abnormal_cell_cycle0.69621852
164MP0005535_abnormal_body_temperature0.68865192
165MP0004133_heterotaxia0.68564962
166MP0003984_embryonic_growth_retardation0.67564706
167MP0006054_spinal_hemorrhage0.66639362
168MP0009672_abnormal_birth_weight0.66514261
169MP0002088_abnormal_embryonic_growth/wei0.66202730
170MP0000266_abnormal_heart_morphology0.66021947
171MP0000003_abnormal_adipose_tissue0.64410064
172MP0004085_abnormal_heartbeat0.62172684
173MP0004272_abnormal_basement_membrane0.61983434
174MP0010368_abnormal_lymphatic_system0.61877685
175MP0002971_abnormal_brown_adipose0.61712202

Predicted human phenotypes

RankGene SetZ-score
1Myoglobinuria (HP:0002913)4.64059998
2Hepatic necrosis (HP:0002605)4.52964947
3Acute necrotizing encephalopathy (HP:0006965)4.15541169
4Acute encephalopathy (HP:0006846)4.11413468
5Abnormal mitochondria in muscle tissue (HP:0008316)4.11174140
6Exercise-induced muscle cramps (HP:0003710)4.10105461
7Rhabdomyolysis (HP:0003201)4.08970897
83-Methylglutaconic aciduria (HP:0003535)4.03284962
9Hepatocellular necrosis (HP:0001404)4.00808819
10Hypoglycemic coma (HP:0001325)3.84900838
11Abnormality of fatty-acid metabolism (HP:0004359)3.80469226
12Mitochondrial inheritance (HP:0001427)3.76139342
13Cerebral edema (HP:0002181)3.72588115
14Increased CSF lactate (HP:0002490)3.61205064
15Abnormality of dicarboxylic acid metabolism (HP:0010995)3.51370413
16Dicarboxylic aciduria (HP:0003215)3.51370413
17Exercise-induced myalgia (HP:0003738)3.50836520
18Ketoacidosis (HP:0001993)3.48393489
19Increased muscle lipid content (HP:0009058)3.39706266
20Ketosis (HP:0001946)3.36216357
21Calf muscle hypertrophy (HP:0008981)3.36061797
22Progressive macrocephaly (HP:0004481)3.32237519
23Decreased activity of mitochondrial respiratory chain (HP:0008972)3.28207019
24Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.28207019
25Lactic acidosis (HP:0003128)3.28114416
26Hyperammonemia (HP:0001987)3.26408235
27Sudden death (HP:0001699)3.26107663
28Increased serum pyruvate (HP:0003542)3.25936185
29Abnormality of glycolysis (HP:0004366)3.25936185
30Generalized aminoaciduria (HP:0002909)3.25604444
31Palpitations (HP:0001962)3.22837406
32Multiple enchondromatosis (HP:0005701)3.20543995
33Hyperglycinuria (HP:0003108)3.20115784
34Type I transferrin isoform profile (HP:0003642)3.15559339
35Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.15402335
36Muscle hypertrophy of the lower extremities (HP:0008968)3.11422171
37Abnormality of aromatic amino acid family metabolism (HP:0004338)3.09655178
38Lipid accumulation in hepatocytes (HP:0006561)3.09148288
39Medial flaring of the eyebrow (HP:0010747)3.04750789
40Increased intramyocellular lipid droplets (HP:0012240)3.01968534
41Abnormality of serine family amino acid metabolism (HP:0010894)2.98404857
42Abnormality of glycine metabolism (HP:0010895)2.98404857
43Pancreatic cysts (HP:0001737)2.90812196
44Pancreatic fibrosis (HP:0100732)2.90389450
45Conjunctival hamartoma (HP:0100780)2.89187650
46Exercise intolerance (HP:0003546)2.89144518
47Hyperglycinemia (HP:0002154)2.85754227
48Lethargy (HP:0001254)2.83483425
49Respiratory failure (HP:0002878)2.83459176
50Pheochromocytoma (HP:0002666)2.81848864
51Methylmalonic acidemia (HP:0002912)2.81496990
52Increased serum lactate (HP:0002151)2.79454428
53Optic disc pallor (HP:0000543)2.78326298
54Neuroendocrine neoplasm (HP:0100634)2.78233225
55Muscle fiber splitting (HP:0003555)2.77886503
56Progressive muscle weakness (HP:0003323)2.73002869
57Ventricular tachycardia (HP:0004756)2.72923668
58Exertional dyspnea (HP:0002875)2.70945705
59Neoplasm of the adrenal gland (HP:0100631)2.65870755
60Myokymia (HP:0002411)2.62876858
61Lipoatrophy (HP:0100578)2.62517145
62Increased hepatocellular lipid droplets (HP:0006565)2.61768945
63Ragged-red muscle fibers (HP:0003200)2.59413501
64Gout (HP:0001997)2.55168611
65Gait imbalance (HP:0002141)2.54899022
66True hermaphroditism (HP:0010459)2.53459823
67Congenital primary aphakia (HP:0007707)2.53346858
68CNS demyelination (HP:0007305)2.51243514
69Myotonia (HP:0002486)2.47774092
70Reduced antithrombin III activity (HP:0001976)2.47302022
71Molar tooth sign on MRI (HP:0002419)2.46909721
72Abnormality of midbrain morphology (HP:0002418)2.46909721
73Nausea (HP:0002018)2.45009331
74Abnormal protein glycosylation (HP:0012346)2.43856320
75Abnormal glycosylation (HP:0012345)2.43856320
76Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.43856320
77Abnormal protein N-linked glycosylation (HP:0012347)2.43856320
78Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.41641235
79Asymmetric septal hypertrophy (HP:0001670)2.40070824
80Abnormality of urine glucose concentration (HP:0011016)2.39676946
81Glycosuria (HP:0003076)2.39676946
82Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.37380266
83Abnormality of alanine metabolism (HP:0010916)2.37380266
84Hyperalaninemia (HP:0003348)2.37380266
85Dilated cardiomyopathy (HP:0001644)2.35573670
86Abnormality of renal resorption (HP:0011038)2.35492939
87Abnormal cartilage morphology (HP:0002763)2.34455053
88Abnormality of the calf musculature (HP:0001430)2.30870856
89Nephrogenic diabetes insipidus (HP:0009806)2.30042777
90Macrocytic anemia (HP:0001972)2.28615714
91Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.27026573
92Type 2 muscle fiber atrophy (HP:0003554)2.26156626
93Hyperinsulinemic hypoglycemia (HP:0000825)2.23649401
94X-linked dominant inheritance (HP:0001423)2.22893865
95Muscle stiffness (HP:0003552)2.21410070
96Abnormality of cells of the erythroid lineage (HP:0012130)2.20074784
97Proximal tubulopathy (HP:0000114)2.19855620
98Methylmalonic aciduria (HP:0012120)2.19126730
99EMG: myopathic abnormalities (HP:0003458)2.18094221
100Vomiting (HP:0002013)2.18045806
101Hypothermia (HP:0002045)2.16062385
102Reticulocytopenia (HP:0001896)2.15013818
103Metabolic acidosis (HP:0001942)2.13399472
104Delayed CNS myelination (HP:0002188)2.10174084
105Nephronophthisis (HP:0000090)2.08436527
106Abnormality of serum amino acid levels (HP:0003112)2.07848621
107Abnormality of methionine metabolism (HP:0010901)2.06519616
108Renal Fanconi syndrome (HP:0001994)2.04910492
109Neoplasm of head and neck (HP:0012288)2.03673726
110Esophageal neoplasm (HP:0100751)2.03673726
111Late onset (HP:0003584)2.03648912
112Abnormality of the left ventricular outflow tract (HP:0011103)2.02207293
113Subaortic stenosis (HP:0001682)2.02207293
114Hyperphosphaturia (HP:0003109)2.01712835
115Abnormality of the anterior horn cell (HP:0006802)2.01497412
116Degeneration of anterior horn cells (HP:0002398)2.01497412
117Hyporeflexia of lower limbs (HP:0002600)2.00965870
118Muscle fiber inclusion bodies (HP:0100299)1.99593008
119Congenital, generalized hypertrichosis (HP:0004540)1.99553604
120Limb-girdle muscle atrophy (HP:0003797)1.99461920
121Genital tract atresia (HP:0001827)1.99127193
122Xanthomatosis (HP:0000991)1.98740742
123Increased purine levels (HP:0004368)1.97073245
124Hyperuricemia (HP:0002149)1.97073245
125Emotional lability (HP:0000712)1.94992868
126Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.94084216
127Leukodystrophy (HP:0002415)1.92876993
128Vaginal atresia (HP:0000148)1.92497177
129Muscle fiber atrophy (HP:0100295)1.91698400
130Abnormality of aspartate family amino acid metabolism (HP:0010899)1.91364438
131Abnormality of the labia minora (HP:0012880)1.90159265
132Neoplasm of the peripheral nervous system (HP:0100007)1.89390643
133Oral leukoplakia (HP:0002745)1.86970925
134Abnormal biliary tract physiology (HP:0012439)1.86780742
135Bile duct proliferation (HP:0001408)1.86780742
136Poor coordination (HP:0002370)1.84444232
137Sclerocornea (HP:0000647)1.83072628
138Abnormal number of erythroid precursors (HP:0012131)1.82207013
139Cerebral hypomyelination (HP:0006808)1.81966180
140Abnormality of purine metabolism (HP:0004352)1.80634551
141Renal cortical cysts (HP:0000803)1.79766809
142Testicular atrophy (HP:0000029)1.79470215
143Hypobetalipoproteinemia (HP:0003563)1.78994763
144Type 1 muscle fiber predominance (HP:0003803)1.78770271
145Respiratory difficulties (HP:0002880)1.78359310
146Cavernous hemangioma (HP:0001048)1.78103627
147Aplastic anemia (HP:0001915)1.77594931
148Septo-optic dysplasia (HP:0100842)1.73236527
149Large for gestational age (HP:0001520)1.71106374
150Abnormality of the renal cortex (HP:0011035)1.70723424
151Abnormality of the renal medulla (HP:0100957)1.69138139
152Amniotic constriction ring (HP:0009775)1.67266321
153Abnormality of placental membranes (HP:0011409)1.67266321
154Pancreatic islet-cell hyperplasia (HP:0004510)1.65027672
155Abnormality of the pons (HP:0007361)1.64497748
156Atonic seizures (HP:0010819)1.63349485

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.31256790
2BUB13.47902660
3NME23.30454116
4NEK13.18878123
5TRIB33.09246331
6PDK33.06762318
7PDK43.06762318
8MST42.71201092
9VRK22.66992197
10OBSCN2.65043022
11FRK2.60981074
12MAP4K22.57980897
13PKN22.55734294
14EIF2AK12.48565897
15TESK12.38494490
16TTN2.34217261
17NUAK12.06308857
18MYLK2.03859060
19PHKG11.93936963
20PHKG21.93936963
21BMPR1B1.88439686
22LIMK11.87362884
23MAPKAPK31.84232386
24TNIK1.80443780
25EPHA41.80300947
26LMTK21.80206960
27ILK1.68188268
28ZAK1.64820839
29TSSK61.56585107
30PDK21.55252068
31ADRBK21.51775705
32LRRK21.51532126
33PINK11.50767065
34TRIM281.50180110
35GRK11.47011412
36PLK21.46620560
37DYRK31.44763413
38FLT31.44726682
39MAP3K121.42369977
40ERN11.41782228
41ARAF1.40728832
42TESK21.37992381
43MAP2K31.34019697
44WNK41.33555087
45PBK1.33311115
46MAP3K111.32594151
47MAP3K41.26025835
48WEE11.24065739
49PIM21.18524035
50MKNK11.17068427
51MKNK21.15105724
52ERBB31.12622980
53SCYL21.07175781
54NME11.05935847
55EIF2AK31.05348882
56KDR1.03681908
57PRKCG1.03055199
58MAPK131.01452101
59CSNK1G10.99180877
60NTRK30.97242172
61CSNK1G20.95072730
62BCR0.95061930
63BRSK10.93271212
64CSNK1G30.92747697
65PASK0.92550263
66CASK0.91488792
67RPS6KB20.90147490
68STK38L0.90116031
69WNK30.89757439
70FGFR20.89528676
71NEK90.89188117
72MAP3K100.87464550
73PNCK0.86475940
74DAPK30.86042004
75ACVR1B0.85786976
76MAP2K70.85682023
77INSRR0.85629612
78PRKCE0.84735562
79BRAF0.84073741
80PAK40.83081052
81TGFBR10.82992077
82OXSR10.81267303
83PIK3CG0.80498215
84BRSK20.78656566
85EPHB20.76266733
86MINK10.76212921
87MAP3K30.76189521
88MAPKAPK50.75371608
89ABL20.75351068
90AURKA0.73503280
91CDK190.73488140
92TLK10.72998798
93MARK10.69260866
94STK240.68493216
95DAPK20.64709827
96EEF2K0.63293500
97GRK50.62232657
98STK160.61785488
99TTK0.61137152
100MAP2K60.60977761
101PRKD30.60830922
102CSNK1A1L0.58991499
103CAMK2A0.58493522
104PTK60.58090572
105DAPK10.57424583
106DYRK1B0.56879070
107TIE10.55820587
108AURKB0.53830855
109PRKACA0.51329760
110MAP3K80.49337310
111PDGFRA0.49018721
112RPS6KA50.48399124
113PAK30.47689505
114SIK10.47521444
115VRK10.46977629
116CCNB10.46609593
117RPS6KA40.45654293
118DYRK20.44252463
119RPS6KC10.44053705
120RPS6KL10.44053705
121TAOK30.43775403
122MAP2K20.43766384
123CDK30.43736873
124GRK70.43455116
125PAK10.42588901
126CSNK1A10.41591609
127ADRBK10.41388844
128MAP3K50.40879236
129CSNK1E0.40048183
130RPS6KA60.39891426
131STK390.39516699
132TAF10.39347804
133CAMKK20.39297329
134ATM0.38546093
135PRKG10.38398608
136ATR0.37573899
137CDC70.37226533
138PLK10.36723264
139PRKCA0.36324609
140CAMK2D0.36196432
141MAP2K10.35856491
142SRPK10.35609113
143MUSK0.35381215
144MAPK150.34788957
145CSNK2A10.33501278
146PRKG20.32640479
147RPS6KA10.31770981
148UHMK10.31450162
149FGFR40.31285688
150PRKD10.30839740
151NEK20.30489836
152PLK40.29697876
153PRKAA10.29570159
154AKT20.27798315
155ROCK10.27200105
156MAPKAPK20.27055021
157RPS6KA20.25393685
158PLK30.24373432
159CSNK2A20.23647204
160MAPK110.21973959
161TBK10.21433845

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.29848920
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.31179875
3Propanoate metabolism_Homo sapiens_hsa006403.06420504
4Parkinsons disease_Homo sapiens_hsa050122.92886337
5Oxidative phosphorylation_Homo sapiens_hsa001902.89438160
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.78632127
7Ribosome_Homo sapiens_hsa030102.69270861
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.65822642
9Proteasome_Homo sapiens_hsa030502.59497601
10Fatty acid degradation_Homo sapiens_hsa000712.55754143
11Carbon metabolism_Homo sapiens_hsa012002.47081438
12Pyruvate metabolism_Homo sapiens_hsa006202.30577284
13Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.21724573
14Fatty acid metabolism_Homo sapiens_hsa012121.98245316
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.91716580
16Biosynthesis of amino acids_Homo sapiens_hsa012301.86075779
17Huntingtons disease_Homo sapiens_hsa050161.85736929
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.84675876
19Alzheimers disease_Homo sapiens_hsa050101.79618680
20Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.73774175
21Cardiac muscle contraction_Homo sapiens_hsa042601.69725707
22Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.64693887
23Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.64689766
24Folate biosynthesis_Homo sapiens_hsa007901.62841110
25Butanoate metabolism_Homo sapiens_hsa006501.61606499
26Tryptophan metabolism_Homo sapiens_hsa003801.55021864
27Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.53650064
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.50473753
29Protein export_Homo sapiens_hsa030601.47055145
30Peroxisome_Homo sapiens_hsa041461.47039252
31Sulfur relay system_Homo sapiens_hsa041221.44252454
32Fatty acid elongation_Homo sapiens_hsa000621.43426460
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.40494851
34Fanconi anemia pathway_Homo sapiens_hsa034601.38465856
35Basal transcription factors_Homo sapiens_hsa030221.33734234
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.27455727
37DNA replication_Homo sapiens_hsa030301.24088725
38beta-Alanine metabolism_Homo sapiens_hsa004101.21961141
39RNA polymerase_Homo sapiens_hsa030201.21320343
40Phototransduction_Homo sapiens_hsa047441.21277257
41Sulfur metabolism_Homo sapiens_hsa009201.19782173
42Arginine biosynthesis_Homo sapiens_hsa002201.17835898
43PPAR signaling pathway_Homo sapiens_hsa033201.16331501
44Pentose phosphate pathway_Homo sapiens_hsa000301.16323131
45Nicotine addiction_Homo sapiens_hsa050331.13989723
46Pyrimidine metabolism_Homo sapiens_hsa002401.13685169
47Phenylalanine metabolism_Homo sapiens_hsa003601.11629860
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.11534514
49Collecting duct acid secretion_Homo sapiens_hsa049661.11495766
50Arginine and proline metabolism_Homo sapiens_hsa003301.09046007
51Selenocompound metabolism_Homo sapiens_hsa004501.03835512
52Pentose and glucuronate interconversions_Homo sapiens_hsa000401.02257501
53Glutathione metabolism_Homo sapiens_hsa004801.00735474
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.99928138
55Tyrosine metabolism_Homo sapiens_hsa003500.98293019
56Starch and sucrose metabolism_Homo sapiens_hsa005000.98047884
57Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.91830861
58Steroid biosynthesis_Homo sapiens_hsa001000.91777721
59Fat digestion and absorption_Homo sapiens_hsa049750.89987264
60Galactose metabolism_Homo sapiens_hsa000520.89960210
61Fructose and mannose metabolism_Homo sapiens_hsa000510.88403950
62Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.88186575
63One carbon pool by folate_Homo sapiens_hsa006700.84550949
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79065181
65Metabolic pathways_Homo sapiens_hsa011000.78357631
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74389765
67Mismatch repair_Homo sapiens_hsa034300.73592856
68Nitrogen metabolism_Homo sapiens_hsa009100.71916888
69Regulation of autophagy_Homo sapiens_hsa041400.69944459
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.69707884
71GABAergic synapse_Homo sapiens_hsa047270.67906463
72Spliceosome_Homo sapiens_hsa030400.66657108
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.66253217
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66179293
75Non-homologous end-joining_Homo sapiens_hsa034500.65943871
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65913922
77Linoleic acid metabolism_Homo sapiens_hsa005910.65894175
78Base excision repair_Homo sapiens_hsa034100.65723496
79Cyanoamino acid metabolism_Homo sapiens_hsa004600.64246660
80RNA transport_Homo sapiens_hsa030130.63920886
81Olfactory transduction_Homo sapiens_hsa047400.62874240
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61902724
83Maturity onset diabetes of the young_Homo sapiens_hsa049500.60010185
84Purine metabolism_Homo sapiens_hsa002300.56772872
85Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.55500094
86Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.54770692
87Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.53663829
88Chemical carcinogenesis_Homo sapiens_hsa052040.49784493
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.49203294
90Vitamin B6 metabolism_Homo sapiens_hsa007500.48792418
91Synaptic vesicle cycle_Homo sapiens_hsa047210.48366723
92Histidine metabolism_Homo sapiens_hsa003400.48016913
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46614441
94Morphine addiction_Homo sapiens_hsa050320.45340193
95Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.44824308
96Insulin secretion_Homo sapiens_hsa049110.44567887
97Taste transduction_Homo sapiens_hsa047420.44443238
98Dilated cardiomyopathy_Homo sapiens_hsa054140.43254234
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.42505623
100Circadian entrainment_Homo sapiens_hsa047130.42396735
101Glucagon signaling pathway_Homo sapiens_hsa049220.41450066
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38405993
103Oocyte meiosis_Homo sapiens_hsa041140.38242134
104Nucleotide excision repair_Homo sapiens_hsa034200.38060070
105Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.37338622
106Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.36282322
107Glycerolipid metabolism_Homo sapiens_hsa005610.34612843
108N-Glycan biosynthesis_Homo sapiens_hsa005100.34455565
109Ether lipid metabolism_Homo sapiens_hsa005650.33702815
110Serotonergic synapse_Homo sapiens_hsa047260.33655874
111Central carbon metabolism in cancer_Homo sapiens_hsa052300.30522569
112Glutamatergic synapse_Homo sapiens_hsa047240.29933213
113Dopaminergic synapse_Homo sapiens_hsa047280.29394421
114Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.29240616
115Arachidonic acid metabolism_Homo sapiens_hsa005900.28826042
116AMPK signaling pathway_Homo sapiens_hsa041520.28571012
117Insulin signaling pathway_Homo sapiens_hsa049100.28236033
118Cell cycle_Homo sapiens_hsa041100.22668686
119Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.22615364
120Systemic lupus erythematosus_Homo sapiens_hsa053220.22461341
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.22021754
122Caffeine metabolism_Homo sapiens_hsa002320.21967031
123Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.20873774
124Homologous recombination_Homo sapiens_hsa034400.20170014
125Fatty acid biosynthesis_Homo sapiens_hsa000610.18736693
126Insulin resistance_Homo sapiens_hsa049310.18410339
127Bile secretion_Homo sapiens_hsa049760.17526345
128Complement and coagulation cascades_Homo sapiens_hsa046100.16244566
129Vibrio cholerae infection_Homo sapiens_hsa051100.15401448
130HIF-1 signaling pathway_Homo sapiens_hsa040660.15264486
131RNA degradation_Homo sapiens_hsa030180.15100929
132Retinol metabolism_Homo sapiens_hsa008300.12860016

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