

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | histone H4-K8 acetylation (GO:0043982) | 8.69575770 |
| 2 | histone H4-K5 acetylation (GO:0043981) | 8.69575770 |
| 3 | negative regulation of stress fiber assembly (GO:0051497) | 8.52860388 |
| 4 | negative regulation of protein localization to plasma membrane (GO:1903077) | 8.43643837 |
| 5 | DNA deamination (GO:0045006) | 7.57526703 |
| 6 | negative regulation of actin filament bundle assembly (GO:0032232) | 7.05183367 |
| 7 | histone H4-K16 acetylation (GO:0043984) | 6.78868490 |
| 8 | negative regulation of establishment of protein localization to plasma membrane (GO:0090005) | 6.75878957 |
| 9 | retinal rod cell development (GO:0046548) | 6.71347884 |
| 10 | negative regulation by host of viral transcription (GO:0043922) | 6.61450347 |
| 11 | regulation of relaxation of muscle (GO:1901077) | 6.45517636 |
| 12 | regulation of lymphocyte chemotaxis (GO:1901623) | 5.87030478 |
| 13 | ribonucleoside bisphosphate biosynthetic process (GO:0034030) | 5.81699935 |
| 14 | nucleoside bisphosphate biosynthetic process (GO:0033866) | 5.81699935 |
| 15 | purine nucleoside bisphosphate biosynthetic process (GO:0034033) | 5.81699935 |
| 16 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 5.79500963 |
| 17 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 5.79500963 |
| 18 | regulation of cell communication by electrical coupling (GO:0010649) | 5.62656640 |
| 19 | negative regulation of T cell mediated immunity (GO:0002710) | 5.58340868 |
| 20 | regulation of protein polyubiquitination (GO:1902914) | 5.48239876 |
| 21 | lateral ventricle development (GO:0021670) | 5.40369806 |
| 22 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.39629321 |
| 23 | cAMP-mediated signaling (GO:0019933) | 5.33154500 |
| 24 | maturation of 5.8S rRNA (GO:0000460) | 5.18917290 |
| 25 | mitotic sister chromatid cohesion (GO:0007064) | 4.95421403 |
| 26 | retinal cone cell development (GO:0046549) | 4.94333799 |
| 27 | peptidyl-histidine modification (GO:0018202) | 4.92259301 |
| 28 | GDP-mannose metabolic process (GO:0019673) | 4.92112147 |
| 29 | cellular response to epinephrine stimulus (GO:0071872) | 4.82045038 |
| 30 | rRNA transcription (GO:0009303) | 4.81598238 |
| 31 | parturition (GO:0007567) | 4.80106860 |
| 32 | regulation of cardiac muscle cell contraction (GO:0086004) | 4.55423889 |
| 33 | negative regulation of gene silencing (GO:0060969) | 4.52098229 |
| 34 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.46143579 |
| 35 | iron ion import (GO:0097286) | 4.45306340 |
| 36 | glycerophospholipid catabolic process (GO:0046475) | 4.28442757 |
| 37 | adrenergic receptor signaling pathway (GO:0071875) | 4.25585401 |
| 38 | regulation of protein localization to plasma membrane (GO:1903076) | 4.20062852 |
| 39 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 4.17431896 |
| 40 | regulation of chronic inflammatory response (GO:0002676) | 4.13615547 |
| 41 | viral mRNA export from host cell nucleus (GO:0046784) | 4.11996110 |
| 42 | positive regulation of gene expression, epigenetic (GO:0045815) | 4.01919804 |
| 43 | cytidine deamination (GO:0009972) | 4.01509933 |
| 44 | cytidine metabolic process (GO:0046087) | 4.01509933 |
| 45 | cytidine catabolic process (GO:0006216) | 4.01509933 |
| 46 | negative regulation of interleukin-2 production (GO:0032703) | 4.00985868 |
| 47 | response to epinephrine (GO:0071871) | 3.98021003 |
| 48 | negative regulation of DNA repair (GO:0045738) | 3.88402840 |
| 49 | negative regulation of cell killing (GO:0031342) | 3.84218966 |
| 50 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.84218966 |
| 51 | positive regulation of gastrulation (GO:2000543) | 3.83119759 |
| 52 | regulation of B cell differentiation (GO:0045577) | 3.82014390 |
| 53 | regulation of interleukin-5 production (GO:0032674) | 3.73386793 |
| 54 | cyclic-nucleotide-mediated signaling (GO:0019935) | 3.73040053 |
| 55 | positive regulation of lymphocyte migration (GO:2000403) | 3.69131202 |
| 56 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.69079622 |
| 57 | negative regulation of viral transcription (GO:0032897) | 3.68322707 |
| 58 | inner mitochondrial membrane organization (GO:0007007) | 3.66804453 |
| 59 | somatic stem cell division (GO:0048103) | 3.62851341 |
| 60 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.58884032 |
| 61 | cAMP catabolic process (GO:0006198) | 3.56249214 |
| 62 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.55052130 |
| 63 | regulation of viral entry into host cell (GO:0046596) | 3.52263095 |
| 64 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.51732562 |
| 65 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.49235062 |
| 66 | regulation of actin filament-based movement (GO:1903115) | 3.48428025 |
| 67 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.47555024 |
| 68 | negative regulation of heart contraction (GO:0045822) | 3.44144617 |
| 69 | CDP-diacylglycerol biosynthetic process (GO:0016024) | 3.37424538 |
| 70 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.37280056 |
| 71 | protein neddylation (GO:0045116) | 3.37102782 |
| 72 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.36559529 |
| 73 | regulation of establishment of protein localization to plasma membrane (GO:0090003) | 3.35961517 |
| 74 | eye photoreceptor cell development (GO:0042462) | 3.35403867 |
| 75 | myeloid dendritic cell differentiation (GO:0043011) | 3.31794476 |
| 76 | DNA strand renaturation (GO:0000733) | 3.31751935 |
| 77 | regulation of calcium-mediated signaling (GO:0050848) | 3.28933352 |
| 78 | negative regulation of viral release from host cell (GO:1902187) | 3.17174342 |
| 79 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.15166994 |
| 80 | photoreceptor cell development (GO:0042461) | 3.14694479 |
| 81 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.07414657 |
| 82 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.07077364 |
| 83 | phosphorelay signal transduction system (GO:0000160) | 3.03905639 |
| 84 | mitochondrial calcium ion transport (GO:0006851) | 3.03382420 |
| 85 | cyclic nucleotide catabolic process (GO:0009214) | 3.02312084 |
| 86 | positive regulation of heart rate (GO:0010460) | 3.00462523 |
| 87 | UTP metabolic process (GO:0046051) | 3.00423907 |
| 88 | mast cell degranulation (GO:0043303) | 2.96441251 |
| 89 | mast cell activation involved in immune response (GO:0002279) | 2.96441251 |
| 90 | plasma lipoprotein particle assembly (GO:0034377) | 2.96159097 |
| 91 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.96110304 |
| 92 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.95328311 |
| 93 | UTP biosynthetic process (GO:0006228) | 2.93769268 |
| 94 | negative regulation of oxidoreductase activity (GO:0051354) | 2.93570586 |
| 95 | regulation of ARF GTPase activity (GO:0032312) | 2.93212806 |
| 96 | replication fork processing (GO:0031297) | 2.91150235 |
| 97 | GTP biosynthetic process (GO:0006183) | 2.84272849 |
| 98 | CDP-diacylglycerol metabolic process (GO:0046341) | 2.84003011 |
| 99 | positive regulation of humoral immune response (GO:0002922) | 2.81492560 |
| 100 | myeloid dendritic cell activation (GO:0001773) | 2.80364411 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 6.70968949 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.14839185 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.30265393 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.28986523 |
| 5 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.95142416 |
| 6 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.93901855 |
| 7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.40334499 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.15504298 |
| 9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.15404632 |
| 10 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 15.8584174 |
| 11 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.93990608 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.87938471 |
| 13 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.56768765 |
| 14 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.53040612 |
| 15 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.46094152 |
| 16 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.41513681 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.37566403 |
| 18 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.34006423 |
| 19 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.29495409 |
| 20 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.23209339 |
| 21 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.19547919 |
| 22 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.17607703 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.17166250 |
| 24 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.16807718 |
| 25 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.12289833 |
| 26 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.11943753 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.07845069 |
| 28 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.97025877 |
| 29 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.96350373 |
| 30 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95655436 |
| 31 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.94749288 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.93540290 |
| 33 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.93159310 |
| 34 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92051882 |
| 35 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.91775532 |
| 36 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91071770 |
| 37 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.90797040 |
| 38 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.87506019 |
| 39 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.86862088 |
| 40 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.86673842 |
| 41 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.86609444 |
| 42 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.86458747 |
| 43 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85384353 |
| 44 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.85113977 |
| 45 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.84845513 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.84819141 |
| 47 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.81882805 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.81561018 |
| 49 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.81428293 |
| 50 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.81263362 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 0.80994595 |
| 52 | MYB_26560356_Chip-Seq_TH1_Human | 0.80663771 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.80595400 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.80595400 |
| 55 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.80531247 |
| 56 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.80528798 |
| 57 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.80211980 |
| 58 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.79987015 |
| 59 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.79802984 |
| 60 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.79419203 |
| 61 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.79042244 |
| 62 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.78099116 |
| 63 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.78099116 |
| 64 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.76822638 |
| 65 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.76746141 |
| 66 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.75889728 |
| 67 | CBP_21632823_ChIP-Seq_H3396_Human | 0.75881753 |
| 68 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.75457240 |
| 69 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.75338027 |
| 70 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.74680847 |
| 71 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.74204889 |
| 72 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.73664001 |
| 73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.73509058 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.73403562 |
| 75 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.72615716 |
| 76 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.71678788 |
| 77 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.71659153 |
| 78 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.71384479 |
| 79 | STAT3_23295773_ChIP-Seq_U87_Human | 0.70947394 |
| 80 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.70218104 |
| 81 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.69670551 |
| 82 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.69664171 |
| 83 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.69396447 |
| 84 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.69340398 |
| 85 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.69064056 |
| 86 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.68223034 |
| 87 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.67433947 |
| 88 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.66397648 |
| 89 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.65893124 |
| 90 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.65545973 |
| 91 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.65160385 |
| 92 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.64958622 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.63441274 |
| 94 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.63388360 |
| 95 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.62966750 |
| 96 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.62707014 |
| 97 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.62574909 |
| 98 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.61934667 |
| 99 | P300_19829295_ChIP-Seq_ESCs_Human | 0.61632592 |
| 100 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.61597138 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002653_abnormal_ependyma_morphology | 7.84852727 |
| 2 | MP0002822_catalepsy | 3.91773256 |
| 3 | MP0009333_abnormal_splenocyte_physiolog | 3.85681506 |
| 4 | MP0003436_decreased_susceptibility_to | 3.52611662 |
| 5 | MP0001346_abnormal_lacrimal_gland | 2.82282429 |
| 6 | MP0001501_abnormal_sleep_pattern | 2.63683493 |
| 7 | MP0005551_abnormal_eye_electrophysiolog | 2.63432034 |
| 8 | MP0004145_abnormal_muscle_electrophysio | 2.52594284 |
| 9 | MP0000569_abnormal_digit_pigmentation | 2.46240984 |
| 10 | MP0004742_abnormal_vestibular_system | 2.30913545 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.28904509 |
| 12 | MP0000371_diluted_coat_color | 2.14752646 |
| 13 | MP0001986_abnormal_taste_sensitivity | 2.13305906 |
| 14 | MP0005253_abnormal_eye_physiology | 2.11172486 |
| 15 | MP0008775_abnormal_heart_ventricle | 2.10592914 |
| 16 | MP0003950_abnormal_plasma_membrane | 1.98740289 |
| 17 | MP0005367_renal/urinary_system_phenotyp | 1.98504863 |
| 18 | MP0000516_abnormal_urinary_system | 1.98504863 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 1.93002026 |
| 20 | MP0001324_abnormal_eye_pigmentation | 1.83182430 |
| 21 | MP0001299_abnormal_eye_distance/ | 1.78189865 |
| 22 | MP0004510_myositis | 1.69586828 |
| 23 | MP0002272_abnormal_nervous_system | 1.64953270 |
| 24 | MP0004957_abnormal_blastocyst_morpholog | 1.63236443 |
| 25 | MP0005671_abnormal_response_to | 1.59075875 |
| 26 | MP0002234_abnormal_pharynx_morphology | 1.58440760 |
| 27 | MP0005195_abnormal_posterior_eye | 1.57351002 |
| 28 | MP0002751_abnormal_autonomic_nervous | 1.55012705 |
| 29 | MP0000749_muscle_degeneration | 1.54419171 |
| 30 | MP0005248_abnormal_Harderian_gland | 1.54150321 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.43699769 |
| 32 | MP0005387_immune_system_phenotype | 1.38423082 |
| 33 | MP0001790_abnormal_immune_system | 1.38423082 |
| 34 | MP0005391_vision/eye_phenotype | 1.36157727 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.35418440 |
| 36 | MP0001800_abnormal_humoral_immune | 1.32254457 |
| 37 | MP0000015_abnormal_ear_pigmentation | 1.30715226 |
| 38 | MP0002177_abnormal_outer_ear | 1.25081344 |
| 39 | MP0001666_abnormal_nutrient_absorption | 1.22012882 |
| 40 | MP0001727_abnormal_embryo_implantation | 1.20901628 |
| 41 | MP0003866_abnormal_defecation | 1.18616298 |
| 42 | MP0003806_abnormal_nucleotide_metabolis | 1.17920287 |
| 43 | MP0008007_abnormal_cellular_replicative | 1.14496497 |
| 44 | MP0003172_abnormal_lysosome_physiology | 1.12662599 |
| 45 | MP0001486_abnormal_startle_reflex | 1.11024101 |
| 46 | MP0005670_abnormal_white_adipose | 1.10787052 |
| 47 | MP0001873_stomach_inflammation | 1.07709770 |
| 48 | MP0002752_abnormal_somatic_nervous | 1.07072464 |
| 49 | MP0009745_abnormal_behavioral_response | 1.04074209 |
| 50 | MP0004142_abnormal_muscle_tone | 1.02302991 |
| 51 | MP0003638_abnormal_response/metabolism_ | 1.01871356 |
| 52 | MP0003763_abnormal_thymus_physiology | 1.00807621 |
| 53 | MP0001963_abnormal_hearing_physiology | 0.98662263 |
| 54 | MP0001851_eye_inflammation | 0.96394473 |
| 55 | MP0005000_abnormal_immune_tolerance | 0.96329124 |
| 56 | MP0008789_abnormal_olfactory_epithelium | 0.95645884 |
| 57 | MP0003123_paternal_imprinting | 0.94448752 |
| 58 | MP0002735_abnormal_chemical_nociception | 0.93810975 |
| 59 | MP0003943_abnormal_hepatobiliary_system | 0.93040483 |
| 60 | MP0008004_abnormal_stomach_pH | 0.92569444 |
| 61 | MP0004484_altered_response_of | 0.92172005 |
| 62 | MP0003252_abnormal_bile_duct | 0.92106899 |
| 63 | MP0004043_abnormal_pH_regulation | 0.91976923 |
| 64 | MP0008872_abnormal_physiological_respon | 0.91417298 |
| 65 | MP0009764_decreased_sensitivity_to | 0.89408616 |
| 66 | MP0003786_premature_aging | 0.88281608 |
| 67 | MP0002420_abnormal_adaptive_immunity | 0.86648287 |
| 68 | MP0002697_abnormal_eye_size | 0.84919675 |
| 69 | MP0001919_abnormal_reproductive_system | 0.84156692 |
| 70 | MP0005193_abnormal_anterior_eye | 0.81973761 |
| 71 | MP0001819_abnormal_immune_cell | 0.81448251 |
| 72 | MP0000462_abnormal_digestive_system | 0.80405756 |
| 73 | MP0010030_abnormal_orbit_morphology | 0.80250098 |
| 74 | MP0000026_abnormal_inner_ear | 0.79975546 |
| 75 | MP0002102_abnormal_ear_morphology | 0.78515914 |
| 76 | MP0005379_endocrine/exocrine_gland_phen | 0.78486940 |
| 77 | MP0002229_neurodegeneration | 0.77341681 |
| 78 | MP0004233_abnormal_muscle_weight | 0.77104704 |
| 79 | MP0002184_abnormal_innervation | 0.75057772 |
| 80 | MP0005165_increased_susceptibility_to | 0.74467317 |
| 81 | MP0005464_abnormal_platelet_physiology | 0.74277245 |
| 82 | MP0002398_abnormal_bone_marrow | 0.74179814 |
| 83 | MP0003111_abnormal_nucleus_morphology | 0.73572119 |
| 84 | MP0002452_abnormal_antigen_presenting | 0.73534280 |
| 85 | MP0002723_abnormal_immune_serum | 0.72396683 |
| 86 | MP0002877_abnormal_melanocyte_morpholog | 0.70960193 |
| 87 | MP0003890_abnormal_embryonic-extraembry | 0.70143640 |
| 88 | MP0004808_abnormal_hematopoietic_stem | 0.69931577 |
| 89 | MP0008873_increased_physiological_sensi | 0.69823962 |
| 90 | MP0002210_abnormal_sex_determination | 0.69628637 |
| 91 | MP0001663_abnormal_digestive_system | 0.67674947 |
| 92 | MP0002736_abnormal_nociception_after | 0.66597881 |
| 93 | MP0002139_abnormal_hepatobiliary_system | 0.64869817 |
| 94 | MP0003183_abnormal_peptide_metabolism | 0.64381031 |
| 95 | MP0001286_abnormal_eye_development | 0.62479543 |
| 96 | MP0003693_abnormal_embryo_hatching | 0.62188464 |
| 97 | MP0002405_respiratory_system_inflammati | 0.61639949 |
| 98 | MP0001502_abnormal_circadian_rhythm | 0.60983238 |
| 99 | MP0005197_abnormal_uvea_morphology | 0.60978426 |
| 100 | MP0000689_abnormal_spleen_morphology | 0.59733521 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 8.03616003 |
| 2 | Abnormality of alanine metabolism (HP:0010916) | 8.03616003 |
| 3 | Hyperalaninemia (HP:0003348) | 8.03616003 |
| 4 | Posterior subcapsular cataract (HP:0007787) | 7.40323579 |
| 5 | Fair hair (HP:0002286) | 5.98492928 |
| 6 | Alacrima (HP:0000522) | 5.17282275 |
| 7 | Chorioretinal atrophy (HP:0000533) | 4.94589076 |
| 8 | Generalized hypopigmentation of hair (HP:0011358) | 4.70615083 |
| 9 | Mild short stature (HP:0003502) | 4.61152317 |
| 10 | Subcapsular cataract (HP:0000523) | 4.36698590 |
| 11 | Decreased lacrimation (HP:0000633) | 4.23801155 |
| 12 | Orthostatic hypotension (HP:0001278) | 4.17471924 |
| 13 | Tetraparesis (HP:0002273) | 4.04257650 |
| 14 | Abolished electroretinogram (ERG) (HP:0000550) | 3.87398743 |
| 15 | T lymphocytopenia (HP:0005403) | 3.68083725 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.66004433 |
| 17 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.63691489 |
| 18 | Hyperlipoproteinemia (HP:0010980) | 3.58973167 |
| 19 | Central scotoma (HP:0000603) | 3.53176143 |
| 20 | Dysautonomia (HP:0002459) | 3.49895292 |
| 21 | Abnormality of T cell number (HP:0011839) | 3.31731610 |
| 22 | Intestinal atresia (HP:0011100) | 3.21181247 |
| 23 | Scotoma (HP:0000575) | 3.11542444 |
| 24 | Congenital sensorineural hearing impairment (HP:0008527) | 3.08819536 |
| 25 | Pendular nystagmus (HP:0012043) | 3.07425199 |
| 26 | Microretrognathia (HP:0000308) | 3.04275291 |
| 27 | Attenuation of retinal blood vessels (HP:0007843) | 3.01772334 |
| 28 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.95126733 |
| 29 | Abnormality of DNA repair (HP:0003254) | 2.95123545 |
| 30 | Spinal muscular atrophy (HP:0007269) | 2.81508719 |
| 31 | Volvulus (HP:0002580) | 2.76302428 |
| 32 | Abnormality of T cells (HP:0002843) | 2.71766654 |
| 33 | Entropion (HP:0000621) | 2.66799613 |
| 34 | Increased corneal curvature (HP:0100692) | 2.62612152 |
| 35 | Keratoconus (HP:0000563) | 2.62612152 |
| 36 | Polar cataract (HP:0010696) | 2.57763626 |
| 37 | Aplasia cutis congenita (HP:0001057) | 2.57676455 |
| 38 | Encephalitis (HP:0002383) | 2.54986097 |
| 39 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.54910298 |
| 40 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.53902386 |
| 41 | Glucose intolerance (HP:0000833) | 2.52043858 |
| 42 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.50971109 |
| 43 | Oligodactyly (hands) (HP:0001180) | 2.50023319 |
| 44 | Abnormality of T cell physiology (HP:0011840) | 2.48319905 |
| 45 | Abnormality of the renal medulla (HP:0100957) | 2.47506956 |
| 46 | Congenital stationary night blindness (HP:0007642) | 2.44865035 |
| 47 | Abnormal hair whorl (HP:0010721) | 2.43989851 |
| 48 | Recurrent viral infections (HP:0004429) | 2.42727025 |
| 49 | Blue irides (HP:0000635) | 2.38592674 |
| 50 | Hypomagnesemia (HP:0002917) | 2.32953629 |
| 51 | Type II diabetes mellitus (HP:0005978) | 2.32501817 |
| 52 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.31178007 |
| 53 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.30566160 |
| 54 | Abnormal pancreas size (HP:0012094) | 2.26071341 |
| 55 | Hypoplastic nipples (HP:0002557) | 2.21399042 |
| 56 | Ectopic kidney (HP:0000086) | 2.20444964 |
| 57 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.18870801 |
| 58 | Abnormal autonomic nervous system physiology (HP:0012332) | 2.15517616 |
| 59 | Embryonal renal neoplasm (HP:0011794) | 2.15039562 |
| 60 | Nephronophthisis (HP:0000090) | 2.14354393 |
| 61 | Panhypogammaglobulinemia (HP:0003139) | 2.12908995 |
| 62 | Flat occiput (HP:0005469) | 2.11451485 |
| 63 | Constricted visual fields (HP:0001133) | 2.06534463 |
| 64 | Poikiloderma (HP:0001029) | 2.05553294 |
| 65 | Syringomyelia (HP:0003396) | 2.05131303 |
| 66 | Spinal cord lesions (HP:0100561) | 2.05131303 |
| 67 | Photophobia (HP:0000613) | 2.04084588 |
| 68 | Thyroid-stimulating hormone excess (HP:0002925) | 1.98760396 |
| 69 | Abnormality of magnesium homeostasis (HP:0004921) | 1.97356233 |
| 70 | Abnormal glucose tolerance (HP:0001952) | 1.93819622 |
| 71 | Abnormality of the labia minora (HP:0012880) | 1.92713078 |
| 72 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.92542319 |
| 73 | Subaortic stenosis (HP:0001682) | 1.92542319 |
| 74 | Viral hepatitis (HP:0006562) | 1.91551204 |
| 75 | Limited elbow extension (HP:0001377) | 1.91302122 |
| 76 | Increased circulating renin level (HP:0000848) | 1.90591014 |
| 77 | Abnormality of the renal cortex (HP:0011035) | 1.90106167 |
| 78 | Increased nuchal translucency (HP:0010880) | 1.89389819 |
| 79 | Recurrent cutaneous fungal infections (HP:0011370) | 1.88396642 |
| 80 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.88396642 |
| 81 | Spinal canal stenosis (HP:0003416) | 1.88136000 |
| 82 | Delayed CNS myelination (HP:0002188) | 1.87107533 |
| 83 | Late onset (HP:0003584) | 1.85033420 |
| 84 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.84623232 |
| 85 | Abnormality of serum amino acid levels (HP:0003112) | 1.79035407 |
| 86 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.75226815 |
| 87 | Hypoproteinemia (HP:0003075) | 1.74919217 |
| 88 | Rectal fistula (HP:0100590) | 1.71295726 |
| 89 | Rectovaginal fistula (HP:0000143) | 1.71295726 |
| 90 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.70750976 |
| 91 | Microglossia (HP:0000171) | 1.68757271 |
| 92 | Pancreatic cysts (HP:0001737) | 1.67121466 |
| 93 | Primary adrenal insufficiency (HP:0008207) | 1.64655471 |
| 94 | Nasal speech (HP:0001611) | 1.64587264 |
| 95 | Pancreatic fibrosis (HP:0100732) | 1.62816279 |
| 96 | Pulmonary fibrosis (HP:0002206) | 1.61136719 |
| 97 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.61083592 |
| 98 | Severe visual impairment (HP:0001141) | 1.59849415 |
| 99 | Decreased central vision (HP:0007663) | 1.59816874 |
| 100 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.58976188 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 5.64780219 |
| 2 | STK39 | 5.48666754 |
| 3 | WNK4 | 5.14532044 |
| 4 | SCYL2 | 4.75922310 |
| 5 | RIPK4 | 3.93020556 |
| 6 | TLK1 | 3.42785872 |
| 7 | MST4 | 3.22596371 |
| 8 | TRPM7 | 2.91056612 |
| 9 | BMPR2 | 2.85459206 |
| 10 | PIK3CG | 2.37111343 |
| 11 | SIK3 | 2.24081207 |
| 12 | OXSR1 | 2.20018728 |
| 13 | CAMK4 | 2.15959743 |
| 14 | TXK | 2.02909955 |
| 15 | MARK3 | 1.88382359 |
| 16 | SIK2 | 1.72062640 |
| 17 | WNK1 | 1.66095982 |
| 18 | MAP3K12 | 1.64482287 |
| 19 | TAOK3 | 1.58931256 |
| 20 | DYRK3 | 1.57314924 |
| 21 | ERBB4 | 1.54176512 |
| 22 | CAMK1 | 1.47201420 |
| 23 | ALK | 1.33183474 |
| 24 | TAF1 | 1.32416426 |
| 25 | SIK1 | 1.31348981 |
| 26 | NME2 | 1.31161398 |
| 27 | SRPK1 | 1.26261846 |
| 28 | OBSCN | 1.20860614 |
| 29 | RPS6KA4 | 1.12767053 |
| 30 | PAK4 | 1.12292525 |
| 31 | PINK1 | 1.07487209 |
| 32 | IRAK4 | 1.00413405 |
| 33 | MYLK | 0.92450641 |
| 34 | MAP4K2 | 0.86864031 |
| 35 | CAMK2A | 0.76998484 |
| 36 | SGK223 | 0.75526597 |
| 37 | SGK494 | 0.75526597 |
| 38 | WNK3 | 0.74183670 |
| 39 | CDK19 | 0.71446420 |
| 40 | ZAK | 0.68745330 |
| 41 | SGK2 | 0.66484041 |
| 42 | VRK2 | 0.66424907 |
| 43 | ILK | 0.63017573 |
| 44 | ADRBK2 | 0.62066015 |
| 45 | CAMK2D | 0.60211326 |
| 46 | HIPK2 | 0.59934352 |
| 47 | CAMK2B | 0.52318474 |
| 48 | MAP3K8 | 0.51673273 |
| 49 | CSNK1A1L | 0.51425112 |
| 50 | ATR | 0.48429895 |
| 51 | JAK1 | 0.47644640 |
| 52 | EPHA2 | 0.47443536 |
| 53 | DAPK2 | 0.46631807 |
| 54 | PRKD1 | 0.46524924 |
| 55 | TSSK6 | 0.46414672 |
| 56 | CSNK1G3 | 0.46124618 |
| 57 | NEK2 | 0.44516849 |
| 58 | PAK6 | 0.44289958 |
| 59 | CAMK2G | 0.42840674 |
| 60 | PBK | 0.42839742 |
| 61 | PTK2B | 0.38157437 |
| 62 | CSNK1G2 | 0.37314521 |
| 63 | BRAF | 0.37155651 |
| 64 | PDGFRA | 0.36241479 |
| 65 | DAPK1 | 0.35843889 |
| 66 | ATM | 0.35464572 |
| 67 | MAPKAPK5 | 0.35127026 |
| 68 | ABL2 | 0.34146345 |
| 69 | PLK2 | 0.33474693 |
| 70 | MARK2 | 0.33034829 |
| 71 | DYRK1B | 0.31154603 |
| 72 | CSNK1G1 | 0.30207093 |
| 73 | CAMKK2 | 0.29376190 |
| 74 | TEC | 0.28552804 |
| 75 | ERBB3 | 0.27718013 |
| 76 | PDGFRB | 0.27217507 |
| 77 | CSNK1D | 0.25318247 |
| 78 | PRKCQ | 0.25098801 |
| 79 | BCR | 0.23717364 |
| 80 | IRAK3 | 0.23680085 |
| 81 | AKT1 | 0.23250137 |
| 82 | PRKCZ | 0.21733001 |
| 83 | VRK1 | 0.21106838 |
| 84 | MTOR | 0.20957447 |
| 85 | ROCK2 | 0.19294860 |
| 86 | PRKCB | 0.17118417 |
| 87 | IGF1R | 0.16490930 |
| 88 | EPHB2 | 0.15213501 |
| 89 | INSRR | 0.14059724 |
| 90 | ABL1 | 0.13942579 |
| 91 | GSK3A | 0.13829122 |
| 92 | RPS6KA5 | 0.12692685 |
| 93 | ERBB2 | 0.12507280 |
| 94 | DAPK3 | 0.12312010 |
| 95 | MAPK10 | 0.12111315 |
| 96 | MAP3K4 | 0.11339455 |
| 97 | DYRK2 | 0.11296281 |
| 98 | CHEK1 | 0.11221257 |
| 99 | MAP3K3 | 0.09662527 |
| 100 | KDR | 0.08996134 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 3.87348082 |
| 2 | RNA polymerase_Homo sapiens_hsa03020 | 3.84050905 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.90644596 |
| 4 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.84086669 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.67445549 |
| 6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.61347659 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.46448822 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.45866276 |
| 9 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.40284296 |
| 10 | VEGF signaling pathway_Homo sapiens_hsa04370 | 2.25819344 |
| 11 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.20783334 |
| 12 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.15476507 |
| 13 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.99746683 |
| 14 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.93210225 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.90636779 |
| 16 | Morphine addiction_Homo sapiens_hsa05032 | 1.85184564 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.74976394 |
| 18 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.73307981 |
| 19 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.71190721 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.67907983 |
| 21 | Cocaine addiction_Homo sapiens_hsa05030 | 1.65214042 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.64492718 |
| 23 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.61420929 |
| 24 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.61127429 |
| 25 | Circadian rhythm_Homo sapiens_hsa04710 | 1.57911851 |
| 26 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.56903486 |
| 27 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.56670957 |
| 28 | Parkinsons disease_Homo sapiens_hsa05012 | 1.47883865 |
| 29 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.46089692 |
| 30 | Alzheimers disease_Homo sapiens_hsa05010 | 1.35472915 |
| 31 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.25397386 |
| 32 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.25153223 |
| 33 | Proteasome_Homo sapiens_hsa03050 | 1.24290054 |
| 34 | Salmonella infection_Homo sapiens_hsa05132 | 1.21430395 |
| 35 | Long-term potentiation_Homo sapiens_hsa04720 | 1.14929398 |
| 36 | Measles_Homo sapiens_hsa05162 | 1.13698948 |
| 37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.12937514 |
| 38 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.10541750 |
| 39 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.03973272 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.00453689 |
| 41 | Circadian entrainment_Homo sapiens_hsa04713 | 0.95989581 |
| 42 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90794398 |
| 43 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.90615539 |
| 44 | ABC transporters_Homo sapiens_hsa02010 | 0.88523999 |
| 45 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.86604646 |
| 46 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.83799134 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.82460898 |
| 48 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.80841535 |
| 49 | Alcoholism_Homo sapiens_hsa05034 | 0.76959738 |
| 50 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.76805980 |
| 51 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.76416821 |
| 52 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.73169771 |
| 53 | Long-term depression_Homo sapiens_hsa04730 | 0.69810292 |
| 54 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.69760232 |
| 55 | Huntingtons disease_Homo sapiens_hsa05016 | 0.69304719 |
| 56 | GABAergic synapse_Homo sapiens_hsa04727 | 0.67521274 |
| 57 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.67185110 |
| 58 | Renin secretion_Homo sapiens_hsa04924 | 0.65216003 |
| 59 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.63904754 |
| 60 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.62076517 |
| 61 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.60488380 |
| 62 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.57543209 |
| 63 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.55784380 |
| 64 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54943950 |
| 65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.53952289 |
| 66 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.53372493 |
| 67 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.52877943 |
| 68 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.51904754 |
| 69 | Insulin secretion_Homo sapiens_hsa04911 | 0.51271757 |
| 70 | Salivary secretion_Homo sapiens_hsa04970 | 0.50784459 |
| 71 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.50021846 |
| 72 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.49845087 |
| 73 | Endocytosis_Homo sapiens_hsa04144 | 0.49073410 |
| 74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.48463816 |
| 75 | Mineral absorption_Homo sapiens_hsa04978 | 0.48251087 |
| 76 | Taste transduction_Homo sapiens_hsa04742 | 0.47898208 |
| 77 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.47539250 |
| 78 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.47242405 |
| 79 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.43960832 |
| 80 | RNA transport_Homo sapiens_hsa03013 | 0.41800945 |
| 81 | Ribosome_Homo sapiens_hsa03010 | 0.41780155 |
| 82 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.41157760 |
| 83 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.41109814 |
| 84 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.40564878 |
| 85 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.39510045 |
| 86 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.38941198 |
| 87 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.37563677 |
| 88 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.36819704 |
| 89 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34743951 |
| 90 | Amoebiasis_Homo sapiens_hsa05146 | 0.32677616 |
| 91 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.31627914 |
| 92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.29297745 |
| 93 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.29149141 |
| 94 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.28833873 |
| 95 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.27940183 |
| 96 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.27354019 |
| 97 | Prion diseases_Homo sapiens_hsa05020 | 0.26680868 |
| 98 | Peroxisome_Homo sapiens_hsa04146 | 0.24693930 |
| 99 | HTLV-I infection_Homo sapiens_hsa05166 | 0.24627296 |
| 100 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.24353232 |

