TMEM256

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.19108723
2ATP synthesis coupled proton transport (GO:0015986)7.01058351
3energy coupled proton transport, down electrochemical gradient (GO:0015985)7.01058351
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.84407083
5axon ensheathment in central nervous system (GO:0032291)6.76362385
6central nervous system myelination (GO:0022010)6.76362385
7nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)6.66179306
8maturation of SSU-rRNA (GO:0030490)6.28746581
9translational initiation (GO:0006413)6.23495819
10respiratory electron transport chain (GO:0022904)5.98429025
11electron transport chain (GO:0022900)5.83126133
12protein complex disassembly (GO:0043241)5.71110013
13fatty acid elongation (GO:0030497)5.53054339
14ribosomal large subunit biogenesis (GO:0042273)5.52383580
15macromolecular complex disassembly (GO:0032984)5.39792827
16protein neddylation (GO:0045116)5.18384816
17chaperone-mediated protein transport (GO:0072321)4.88489136
18nuclear-transcribed mRNA catabolic process (GO:0000956)4.71482591
19cholesterol biosynthetic process (GO:0006695)4.50238766
20mRNA catabolic process (GO:0006402)4.45712457
21ribosomal small subunit biogenesis (GO:0042274)4.42896358
22aldehyde catabolic process (GO:0046185)4.07603246
23viral transcription (GO:0019083)4.02604052
24RNA catabolic process (GO:0006401)4.00826459
25sterol biosynthetic process (GO:0016126)3.96418265
26cotranslational protein targeting to membrane (GO:0006613)3.92008491
27long-chain fatty acid biosynthetic process (GO:0042759)3.91712152
28regulation of mitochondrial translation (GO:0070129)3.91465729
29NADH dehydrogenase complex assembly (GO:0010257)3.88407530
30mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.88407530
31mitochondrial respiratory chain complex I assembly (GO:0032981)3.88407530
32protein complex biogenesis (GO:0070271)3.86624962
33protein targeting to ER (GO:0045047)3.83155600
34translational termination (GO:0006415)3.79708817
35cellular component biogenesis (GO:0044085)3.78230519
36oxidative phosphorylation (GO:0006119)3.78115074
37SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.77604679
38hydrogen ion transmembrane transport (GO:1902600)3.74444564
39protein localization to endoplasmic reticulum (GO:0070972)3.70364682
40ribonucleoprotein complex biogenesis (GO:0022613)3.69506325
41establishment of protein localization to endoplasmic reticulum (GO:0072599)3.67246922
42establishment of protein localization to membrane (GO:0090150)3.67144514
43substantia nigra development (GO:0021762)3.59960635
44isoprenoid biosynthetic process (GO:0008299)3.58045418
45positive regulation of cellular amine metabolic process (GO:0033240)3.54662681
46protein targeting (GO:0006605)3.54250917
47myelination (GO:0042552)3.50885867
48axon ensheathment (GO:0008366)3.50039849
49ensheathment of neurons (GO:0007272)3.50039849
50sequestering of actin monomers (GO:0042989)3.48822038
51proton transport (GO:0015992)3.46606122
52ATP biosynthetic process (GO:0006754)3.44869662
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.40817580
54establishment of protein localization to mitochondrion (GO:0072655)3.39728698
55nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.38803240
56hydrogen transport (GO:0006818)3.38783087
57purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.38749597
58mitochondrial respiratory chain complex assembly (GO:0033108)3.37528499
59purine nucleoside triphosphate biosynthetic process (GO:0009145)3.36167773
60rRNA modification (GO:0000154)3.32403445
61GPI anchor biosynthetic process (GO:0006506)3.31199264
62establishment of protein localization to organelle (GO:0072594)3.30402021
63spliceosomal snRNP assembly (GO:0000387)3.29987312
64protein localization to mitochondrion (GO:0070585)3.29002403
65exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.25273240
66ribosomal small subunit assembly (GO:0000028)3.19136441
67GTP biosynthetic process (GO:0006183)3.17329368
68nucleoside triphosphate biosynthetic process (GO:0009142)3.16348178
69dopamine transport (GO:0015872)3.16002922
70establishment of protein localization to mitochondrial membrane (GO:0090151)3.13229021
71amyloid precursor protein metabolic process (GO:0042982)3.10980193
72chromatin remodeling at centromere (GO:0031055)3.10903812
73negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.07907276
74negative regulation of ligase activity (GO:0051352)3.07907276
75response to redox state (GO:0051775)3.07430530
76protein-cofactor linkage (GO:0018065)3.07128939
77purine nucleoside monophosphate biosynthetic process (GO:0009127)3.07120205
78purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.07120205
79rRNA processing (GO:0006364)3.07010112
80CENP-A containing nucleosome assembly (GO:0034080)3.06501480
81viral life cycle (GO:0019058)3.05080319
82mitochondrial transport (GO:0006839)3.04552708
83proteasome assembly (GO:0043248)3.04337329
84GPI anchor metabolic process (GO:0006505)3.04038037
85positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.03970990
86formation of translation preinitiation complex (GO:0001731)3.03110309
87regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.02188951
88establishment of integrated proviral latency (GO:0075713)3.02143491
89erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.01281596
90L-phenylalanine catabolic process (GO:0006559)3.01281596
91respiratory chain complex IV assembly (GO:0008535)3.00057122
92mannosylation (GO:0097502)2.99671063
93DNA damage response, detection of DNA damage (GO:0042769)2.97823316
94nucleotide transmembrane transport (GO:1901679)2.97449261
95cellular protein complex disassembly (GO:0043624)2.96124453
96signal peptide processing (GO:0006465)2.96078608
97protein localization to membrane (GO:0072657)2.96053474
987-methylguanosine mRNA capping (GO:0006370)2.96009828
99RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.94125276
100tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.94125276
101anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.92549793
102amyloid precursor protein catabolic process (GO:0042987)2.92365121
103rRNA metabolic process (GO:0016072)2.92351500
104translational elongation (GO:0006414)2.88273553
105RNA capping (GO:0036260)2.87885164
1067-methylguanosine RNA capping (GO:0009452)2.87885164
107ribonucleoside triphosphate biosynthetic process (GO:0009201)2.86687842
108spliceosomal complex assembly (GO:0000245)2.85885578
109deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.85320691
110regulation of cellular amino acid metabolic process (GO:0006521)2.85313943
111dopamine biosynthetic process (GO:0042416)2.84787724
112DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.82632798
113regulation of dopamine metabolic process (GO:0042053)2.76987880
114regulation of catecholamine metabolic process (GO:0042069)2.76987880
115signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.76125370
116signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.76125370
117signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.76125370
118intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.74015947
119negative regulation of protein localization to cell surface (GO:2000009)2.73379866
120cytochrome complex assembly (GO:0017004)2.71533242
121neutrophil activation involved in immune response (GO:0002283)2.71073721
122inner mitochondrial membrane organization (GO:0007007)2.70366779
123glycerophospholipid catabolic process (GO:0046475)2.66570167
124negative regulation of neurotransmitter transport (GO:0051589)2.65774518
125response to methylmercury (GO:0051597)2.65749864
126transcription elongation from RNA polymerase III promoter (GO:0006385)2.64793164
127termination of RNA polymerase III transcription (GO:0006386)2.64793164
128preassembly of GPI anchor in ER membrane (GO:0016254)2.64767109
129regulation of collateral sprouting (GO:0048670)2.64009418
130presynaptic membrane assembly (GO:0097105)2.62542171
131positive regulation of oligodendrocyte differentiation (GO:0048714)2.61285362
132erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.61271655
133L-phenylalanine metabolic process (GO:0006558)2.61271655
134L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.60427942
135protein targeting to membrane (GO:0006612)2.59895334
136oligodendrocyte differentiation (GO:0048709)2.55978344
137presynaptic membrane organization (GO:0097090)2.54663419
138very long-chain fatty acid metabolic process (GO:0000038)2.53607671
139regulation of oxidative phosphorylation (GO:0002082)2.51870085
140platelet dense granule organization (GO:0060155)2.51080748
141translation (GO:0006412)2.50929621
142protein targeting to mitochondrion (GO:0006626)2.49979323
143aerobic respiration (GO:0009060)2.48722472
144cofactor catabolic process (GO:0051187)2.47068954
145neural nucleus development (GO:0048857)2.46992598
146negative regulation of acute inflammatory response (GO:0002674)2.46881936
147intracellular protein transmembrane import (GO:0044743)2.44450758
148neurotransmitter uptake (GO:0001504)2.44016681
149long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.43443970
150mitochondrion morphogenesis (GO:0070584)2.40713852
151C-terminal protein lipidation (GO:0006501)2.40066818
152energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.39714967
153ATP hydrolysis coupled proton transport (GO:0015991)2.39714967
154fatty-acyl-CoA metabolic process (GO:0035337)2.39694862
155UTP biosynthetic process (GO:0006228)2.38439642

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat7.11206317
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.16549716
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.96261064
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.57131000
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.32925306
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.31934819
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.97127395
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.78222148
9MYC_18358816_ChIP-ChIP_MESCs_Mouse2.76587849
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.75236174
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.70634690
12XRN2_22483619_ChIP-Seq_HELA_Human2.56469843
13TTF2_22483619_ChIP-Seq_HELA_Human2.48730972
14TAF15_26573619_Chip-Seq_HEK293_Human2.47173286
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.42861931
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.42643611
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.37803495
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.32582284
19PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.26539380
20VDR_22108803_ChIP-Seq_LS180_Human2.21818394
21FOXP3_21729870_ChIP-Seq_TREG_Human2.19158807
22E2F1_18555785_ChIP-Seq_MESCs_Mouse2.15658819
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.14855956
24CREB1_15753290_ChIP-ChIP_HEK293T_Human2.03464254
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.01863263
26JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.01155181
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.98117038
28GBX2_23144817_ChIP-Seq_PC3_Human1.96892067
29FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.91326201
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.89854090
31ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.84736707
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.82415652
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.77289798
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.75115244
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.74947813
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71796325
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70830890
38CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.70748736
39IRF1_19129219_ChIP-ChIP_H3396_Human1.67478800
40POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.65232778
41HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.62984147
42EGR1_23403033_ChIP-Seq_LIVER_Mouse1.61913941
43GABP_19822575_ChIP-Seq_HepG2_Human1.61305371
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.57787044
45SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56582239
46MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.56193381
47ELF1_17652178_ChIP-ChIP_JURKAT_Human1.53194549
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.46686854
49* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.45919358
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.45007612
51FUS_26573619_Chip-Seq_HEK293_Human1.44018233
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42683726
53JARID2_20064375_ChIP-Seq_MESCs_Mouse1.41737608
54ER_23166858_ChIP-Seq_MCF-7_Human1.40971507
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.40062935
56HTT_18923047_ChIP-ChIP_STHdh_Human1.38260852
57EZH2_27304074_Chip-Seq_ESCs_Mouse1.37801299
58SOX2_18555785_ChIP-Seq_MESCs_Mouse1.36522200
59EED_16625203_ChIP-ChIP_MESCs_Mouse1.35521641
60SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.34029518
61SOX2_16153702_ChIP-ChIP_HESCs_Human1.32384003
62SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.31526516
63PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30261478
64ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.28859101
65PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27583924
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.26537456
67CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25925243
68YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.23892230
69PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.22233416
70ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.21493734
71CTCF_18555785_ChIP-Seq_MESCs_Mouse1.20902741
72POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.20449723
73P300_19829295_ChIP-Seq_ESCs_Human1.20297246
74CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.19093557
75SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.18241838
76RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.17861942
77ELK1_19687146_ChIP-ChIP_HELA_Human1.17516128
78SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.17183168
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16949622
80TP63_19390658_ChIP-ChIP_HaCaT_Human1.14321808
81NANOG_16153702_ChIP-ChIP_HESCs_Human1.12786575
82SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.11808563
83LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.11065981
84STAT1_20625510_ChIP-Seq_HELA_Human1.11040676
85NANOG_18555785_ChIP-Seq_MESCs_Mouse1.08438208
86FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05144844
87TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.04960524
88PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.04823250
89JARID2_20075857_ChIP-Seq_MESCs_Mouse1.04148541
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03865888
91ELK1_22589737_ChIP-Seq_MCF10A_Human1.02431226
92WT1_19549856_ChIP-ChIP_CCG9911_Human1.01566701
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00662068
94SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99825276
95CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99634561
96EZH2_22144423_ChIP-Seq_EOC_Human0.99443034
97GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99171783
98CDX2_19796622_ChIP-Seq_MESCs_Mouse0.98766857
99NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.98576131
100NRF2_20460467_ChIP-Seq_MEFs_Mouse0.98576131
101SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97784532
102SOX2_18692474_ChIP-Seq_MEFs_Mouse0.97742160
103DCP1A_22483619_ChIP-Seq_HELA_Human0.97378606
104PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96984324
105IRF8_21731497_ChIP-ChIP_J774_Mouse0.96014286
106TAL1_26923725_Chip-Seq_HPCs_Mouse0.95052077
107ETV2_25802403_ChIP-Seq_MESCs_Mouse0.94820822
108EZH2_27294783_Chip-Seq_ESCs_Mouse0.94633749
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94341761
110ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.94232246
111MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93398746
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.92911828
113PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.91401355
114SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.90078893
115POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88526010
116RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.88485632
117POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87137573
118MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.86944551
119SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.86188002
120FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.86164751
121SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.86134707
122NANOG_19829295_ChIP-Seq_ESCs_Human0.86109318
123SOX2_19829295_ChIP-Seq_ESCs_Human0.86109318
124MYCN_18555785_ChIP-Seq_MESCs_Mouse0.85963287
125FOXM1_23109430_ChIP-Seq_U2OS_Human0.85680103
126THAP11_20581084_ChIP-Seq_MESCs_Mouse0.85166675
127SOX17_20123909_ChIP-Seq_XEN_Mouse0.84353532
128NANOG_20526341_ChIP-Seq_ESCs_Human0.84297606
129KDM5A_27292631_Chip-Seq_BREAST_Human0.83449180
130OCT4_18692474_ChIP-Seq_MEFs_Mouse0.83060979
131YY1_21170310_ChIP-Seq_MESCs_Mouse0.82826597
132TOP2B_26459242_ChIP-Seq_MCF-7_Human0.82823355
133VDR_23849224_ChIP-Seq_CD4+_Human0.81750768
134TCF3_18692474_ChIP-Seq_MEFs_Mouse0.81334815
135SMAD3_21741376_ChIP-Seq_EPCs_Human0.81054846
136ERG_20517297_ChIP-Seq_VCAP_Human0.81028779
137PCGF2_27294783_Chip-Seq_ESCs_Mouse0.81002503
138FOXP1_21924763_ChIP-Seq_HESCs_Human0.80577631
139RNF2_18974828_ChIP-Seq_MESCs_Mouse0.80360341
140EZH2_18974828_ChIP-Seq_MESCs_Mouse0.80360341
141SUZ12_18555785_Chip-Seq_ESCs_Mouse0.80188609
142MYC_18940864_ChIP-ChIP_HL60_Human0.79708362
143HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79534953
144PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.79498869
145EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.78960313
146CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.78636695
147PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.78625519
148HOXB4_20404135_ChIP-ChIP_EML_Mouse0.78395208
149ERG_20887958_ChIP-Seq_HPC-7_Mouse0.77891929
150EWS_26573619_Chip-Seq_HEK293_Human0.77641603
151ZFX_18555785_ChIP-Seq_MESCs_Mouse0.77395124
152KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.77271989
153KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.77271989
154KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.77271989
155EOMES_21245162_ChIP-Seq_HESCs_Human0.77174640
156RUNX1_27457419_Chip-Seq_LIVER_Mouse0.77080621
157TP53_22573176_ChIP-Seq_HFKS_Human0.75699891
158NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.74898817
159E2F1_21310950_ChIP-Seq_MCF-7_Human0.73617672
160ZNF274_21170338_ChIP-Seq_K562_Hela0.72472581
161E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.69191220
162AR_20517297_ChIP-Seq_VCAP_Human0.68712399

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.91378043
2MP0010030_abnormal_orbit_morphology3.66456366
3MP0000920_abnormal_myelination3.42346194
4MP0003880_abnormal_central_pattern3.39046680
5MP0003136_yellow_coat_color3.37911426
6MP0006292_abnormal_olfactory_placode3.35270450
7MP0001529_abnormal_vocalization3.21081751
8MP0001905_abnormal_dopamine_level3.19497400
9MP0003806_abnormal_nucleotide_metabolis2.63130998
10MP0005409_darkened_coat_color2.48600219
11MP0001293_anophthalmia2.28778726
12MP0004142_abnormal_muscle_tone2.17889687
13MP0004381_abnormal_hair_follicle2.15584398
14MP0004742_abnormal_vestibular_system2.09276803
15MP0003195_calcinosis2.08431709
16MP0005171_absent_coat_pigmentation2.04971948
17MP0003690_abnormal_glial_cell2.01440713
18MP0003186_abnormal_redox_activity1.98364106
19MP0005451_abnormal_body_composition1.96992732
20MP0008789_abnormal_olfactory_epithelium1.92674963
21MP0008058_abnormal_DNA_repair1.91273800
22MP0003011_delayed_dark_adaptation1.90797905
23MP0000566_synostosis1.83292358
24MP0005408_hypopigmentation1.82296669
25MP0006072_abnormal_retinal_apoptosis1.81295119
26MP0004957_abnormal_blastocyst_morpholog1.74952213
27MP0000372_irregular_coat_pigmentation1.74293337
28MP0003283_abnormal_digestive_organ1.72159235
29MP0002272_abnormal_nervous_system1.72112114
30MP0004147_increased_porphyrin_level1.70202971
31MP0000049_abnormal_middle_ear1.68910518
32MP0001986_abnormal_taste_sensitivity1.67268313
33MP0002139_abnormal_hepatobiliary_system1.66058616
34MP0005394_taste/olfaction_phenotype1.65905659
35MP0005499_abnormal_olfactory_system1.65905659
36MP0006036_abnormal_mitochondrial_physio1.65702258
37MP0003693_abnormal_embryo_hatching1.63768941
38MP0006276_abnormal_autonomic_nervous1.63361497
39MP0002234_abnormal_pharynx_morphology1.56507850
40MP0008875_abnormal_xenobiotic_pharmacok1.55814657
41MP0002653_abnormal_ependyma_morphology1.55310269
42MP0001485_abnormal_pinna_reflex1.55278372
43MP0002638_abnormal_pupillary_reflex1.50815246
44MP0002148_abnormal_hypersensitivity_rea1.46513517
45MP0002064_seizures1.46398091
46MP0003724_increased_susceptibility_to1.46323569
47MP0008995_early_reproductive_senescence1.43839790
48MP0001486_abnormal_startle_reflex1.41763863
49MP0005379_endocrine/exocrine_gland_phen1.40946527
50MP0004270_analgesia1.40248140
51MP0003634_abnormal_glial_cell1.39875963
52MP0003315_abnormal_perineum_morphology1.38404110
53MP0000631_abnormal_neuroendocrine_gland1.38129657
54MP0002736_abnormal_nociception_after1.36106379
55MP0005083_abnormal_biliary_tract1.35234220
56MP0003329_amyloid_beta_deposits1.35231465
57MP0002102_abnormal_ear_morphology1.34008220
58MP0008932_abnormal_embryonic_tissue1.32885905
59MP0006082_CNS_inflammation1.31114532
60MP0004043_abnormal_pH_regulation1.29555392
61MP0001346_abnormal_lacrimal_gland1.28187303
62MP0001440_abnormal_grooming_behavior1.28015825
63MP0002734_abnormal_mechanical_nocicepti1.27665526
64MP0009745_abnormal_behavioral_response1.27382149
65MP0004019_abnormal_vitamin_homeostasis1.27331866
66MP0002697_abnormal_eye_size1.23175139
67MP0001968_abnormal_touch/_nociception1.22730686
68MP0003950_abnormal_plasma_membrane1.21308876
69MP0002735_abnormal_chemical_nociception1.20861321
70MP0002163_abnormal_gland_morphology1.19578349
71MP0002160_abnormal_reproductive_system1.19508034
72MP0000778_abnormal_nervous_system1.18829496
73MP0005423_abnormal_somatic_nervous1.18046792
74MP0002229_neurodegeneration1.15944471
75MP0003878_abnormal_ear_physiology1.15111113
76MP0005377_hearing/vestibular/ear_phenot1.15111113
77MP0001286_abnormal_eye_development1.14806321
78MP0003119_abnormal_digestive_system1.14773634
79MP0005551_abnormal_eye_electrophysiolog1.14479644
80MP0009785_altered_susceptibility_to1.13546735
81MP0002233_abnormal_nose_morphology1.13493741
82MP0001970_abnormal_pain_threshold1.13309858
83MP0002938_white_spotting1.13211804
84MP0001984_abnormal_olfaction1.13206915
85MP0010386_abnormal_urinary_bladder1.12328209
86MP0003077_abnormal_cell_cycle1.11065968
87MP0002295_abnormal_pulmonary_circulatio1.10735972
88MP0009046_muscle_twitch1.09909146
89MP0003937_abnormal_limbs/digits/tail_de1.08945600
90MP0002876_abnormal_thyroid_physiology1.08480079
91MP0000537_abnormal_urethra_morphology1.06634097
92MP0004133_heterotaxia1.05292120
93MP0005058_abnormal_lysosome_morphology1.04314843
94MP0001963_abnormal_hearing_physiology1.04220950
95MP0005636_abnormal_mineral_homeostasis1.04220512
96MP0002282_abnormal_trachea_morphology1.02395710
97MP0009697_abnormal_copulation1.01098938
98MP0002733_abnormal_thermal_nociception1.01077026
99MP0003656_abnormal_erythrocyte_physiolo1.00422287
100MP0002277_abnormal_respiratory_mucosa1.00227412
101MP0001727_abnormal_embryo_implantation0.99064296
102MP0005391_vision/eye_phenotype0.98996359
103MP0003718_maternal_effect0.98214552
104MP0002095_abnormal_skin_pigmentation0.97541850
105MP0003941_abnormal_skin_development0.96531904
106MP0010094_abnormal_chromosome_stability0.95794808
107MP0002572_abnormal_emotion/affect_behav0.95660719
108MP0003567_abnormal_fetal_cardiomyocyte0.95287080
109MP0005085_abnormal_gallbladder_physiolo0.95154275
110MP0003632_abnormal_nervous_system0.94334714
111MP0005332_abnormal_amino_acid0.94088677
112MP0000026_abnormal_inner_ear0.94085844
113MP0003786_premature_aging0.93541395
114MP0005084_abnormal_gallbladder_morpholo0.92667478
115MP0001188_hyperpigmentation0.92565605
116MP0002837_dystrophic_cardiac_calcinosis0.92070095
117MP0002132_abnormal_respiratory_system0.90857773
118MP0002210_abnormal_sex_determination0.90741176
119MP0002751_abnormal_autonomic_nervous0.89852450
120MP0005360_urolithiasis0.89706164
121MP0006035_abnormal_mitochondrial_morpho0.88348983
122MP0005410_abnormal_fertilization0.87097511
123MP0005584_abnormal_enzyme/coenzyme_acti0.86936699
124MP0003890_abnormal_embryonic-extraembry0.86781627
125MP0002067_abnormal_sensory_capabilities0.86634324
126MP0003122_maternal_imprinting0.86249518
127MP0004885_abnormal_endolymph0.86147109
128MP0000604_amyloidosis0.83461250
129MP0002090_abnormal_vision0.83280160
130MP0005389_reproductive_system_phenotype0.81459727
131MP0005253_abnormal_eye_physiology0.81183564
132MP0005075_abnormal_melanosome_morpholog0.80440288
133MP0002752_abnormal_somatic_nervous0.79758046
134MP0005164_abnormal_response_to0.79705941
135MP0005025_abnormal_response_to0.78577883
136MP0001324_abnormal_eye_pigmentation0.78171120
137MP0005535_abnormal_body_temperature0.77380425
138MP0005365_abnormal_bile_salt0.74918229
139MP0001661_extended_life_span0.74790407
140MP0001666_abnormal_nutrient_absorption0.74599155
141MP0005000_abnormal_immune_tolerance0.72996414
142MP0005195_abnormal_posterior_eye0.72619180
143MP0002066_abnormal_motor_capabilities/c0.71808369
144MP0000653_abnormal_sex_gland0.71591002
145MP0004924_abnormal_behavior0.71478892
146MP0005386_behavior/neurological_phenoty0.71478892
147MP0002111_abnormal_tail_morphology0.71417319
148MP0002419_abnormal_innate_immunity0.71173170
149MP0005645_abnormal_hypothalamus_physiol0.71081003
150MP0000462_abnormal_digestive_system0.70993767
151MP0009053_abnormal_anal_canal0.70213459
152MP0001764_abnormal_homeostasis0.69779883
153MP0001145_abnormal_male_reproductive0.69648181
154MP0001881_abnormal_mammary_gland0.69260822
155MP0003938_abnormal_ear_development0.69235825
156MP0003631_nervous_system_phenotype0.68958521
157MP0005367_renal/urinary_system_phenotyp0.66893240
158MP0000516_abnormal_urinary_system0.66893240
159MP0001929_abnormal_gametogenesis0.66285421
160MP0000762_abnormal_tongue_morphology0.66049049

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.11333738
2Abnormal mitochondria in muscle tissue (HP:0008316)5.37763776
3Mitochondrial inheritance (HP:0001427)5.36024012
4Acute encephalopathy (HP:0006846)5.25339849
5Progressive macrocephaly (HP:0004481)5.06636083
6Renal Fanconi syndrome (HP:0001994)4.91841051
7Increased hepatocellular lipid droplets (HP:0006565)4.69747550
8Hepatocellular necrosis (HP:0001404)4.47176767
9Increased CSF lactate (HP:0002490)4.33242157
10Parakeratosis (HP:0001036)4.29366693
113-Methylglutaconic aciduria (HP:0003535)4.24724980
12Lipid accumulation in hepatocytes (HP:0006561)4.21931489
13Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.03870311
14Hepatic necrosis (HP:0002605)4.02029036
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.82349749
16Cerebral edema (HP:0002181)3.81706191
17Leukodystrophy (HP:0002415)3.77371394
18Abnormality of glycolysis (HP:0004366)3.73748092
19Increased serum pyruvate (HP:0003542)3.73748092
20Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.54848145
21Increased intramyocellular lipid droplets (HP:0012240)3.45028330
22Sensory axonal neuropathy (HP:0003390)3.30888367
23Optic disc pallor (HP:0000543)3.25868240
24Abnormality of renal resorption (HP:0011038)3.22676054
25Respiratory failure (HP:0002878)3.12277535
26Exertional dyspnea (HP:0002875)3.11632488
27Abnormality of cells of the erythroid lineage (HP:0012130)3.11463930
28Hyperglycinemia (HP:0002154)3.07451999
29Congenital ichthyosiform erythroderma (HP:0007431)3.02503891
30Congenital, generalized hypertrichosis (HP:0004540)3.02414300
31Neurofibrillary tangles (HP:0002185)2.94886618
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.90913479
33Decreased activity of mitochondrial respiratory chain (HP:0008972)2.90913479
34Septo-optic dysplasia (HP:0100842)2.90570946
35Increased muscle lipid content (HP:0009058)2.89818514
36Exercise intolerance (HP:0003546)2.89583545
37Abnormality of aromatic amino acid family metabolism (HP:0004338)2.84743442
38Degeneration of the lateral corticospinal tracts (HP:0002314)2.81575984
39Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.81575984
40Lactic acidosis (HP:0003128)2.76417714
41Abnormal number of erythroid precursors (HP:0012131)2.71467964
42Colon cancer (HP:0003003)2.67168035
43Glycosuria (HP:0003076)2.60604582
44Abnormality of urine glucose concentration (HP:0011016)2.60604582
45Increased serum lactate (HP:0002151)2.55360169
46Hyperphosphaturia (HP:0003109)2.49350735
47Hypothermia (HP:0002045)2.44853489
48Macrocytic anemia (HP:0001972)2.39837900
49Respiratory difficulties (HP:0002880)2.38382915
50Pancreatic fibrosis (HP:0100732)2.36942206
51Pancreatic cysts (HP:0001737)2.32970454
52X-linked dominant inheritance (HP:0001423)2.28787017
53Partial duplication of the phalanx of hand (HP:0009999)2.27723632
54Hepatosplenomegaly (HP:0001433)2.26302693
55Abnormal urine phosphate concentration (HP:0012599)2.22626180
56Renal tubular dysfunction (HP:0000124)2.21170474
57Aplastic anemia (HP:0001915)2.20855587
58True hermaphroditism (HP:0010459)2.20205660
59Peripheral hypomyelination (HP:0007182)2.16558733
60Absent thumb (HP:0009777)2.13172889
61Patchy hypopigmentation of hair (HP:0011365)2.11552863
62Molar tooth sign on MRI (HP:0002419)2.11150721
63Abnormality of midbrain morphology (HP:0002418)2.11150721
64Cerebral hemorrhage (HP:0001342)2.11003209
65Spastic paraparesis (HP:0002313)2.10616794
66Hyperglycinuria (HP:0003108)2.10498671
67Triphalangeal thumb (HP:0001199)2.08043115
68Cerebral hypomyelination (HP:0006808)2.07659592
69Maternal diabetes (HP:0009800)2.06813185
70Reticulocytopenia (HP:0001896)2.05183093
71Absent septum pellucidum (HP:0001331)2.04328543
72Retinal dysplasia (HP:0007973)2.03946823
73Abnormal hemoglobin (HP:0011902)2.03160823
74Lethargy (HP:0001254)1.99951846
75Methylmalonic acidemia (HP:0002912)1.99506890
76Nausea (HP:0002018)1.98258885
77Aplasia/Hypoplasia of the sacrum (HP:0008517)1.97586701
78Microvesicular hepatic steatosis (HP:0001414)1.97073561
79Purpura (HP:0000979)1.95881923
80Vacuolated lymphocytes (HP:0001922)1.95633071
81Abnormality of the axillary hair (HP:0100134)1.94995999
82Abnormality of secondary sexual hair (HP:0009888)1.94995999
83Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.93547942
84Abnormal protein N-linked glycosylation (HP:0012347)1.93547942
85Abnormal protein glycosylation (HP:0012346)1.93547942
86Abnormal glycosylation (HP:0012345)1.93547942
87Abnormality of serine family amino acid metabolism (HP:0010894)1.92118181
88Abnormality of glycine metabolism (HP:0010895)1.92118181
89Abnormality of methionine metabolism (HP:0010901)1.91190958
90Cerebral inclusion bodies (HP:0100314)1.90898453
91Abnormal pupillary function (HP:0007686)1.90333572
92Abnormality of aspartate family amino acid metabolism (HP:0010899)1.90198339
93Neuroendocrine neoplasm (HP:0100634)1.88322087
94CNS demyelination (HP:0007305)1.87819210
95Depressed nasal ridge (HP:0000457)1.87667521
96Abnormality of dicarboxylic acid metabolism (HP:0010995)1.87209206
97Dicarboxylic aciduria (HP:0003215)1.87209206
98Reduced antithrombin III activity (HP:0001976)1.87120492
99Prolonged partial thromboplastin time (HP:0003645)1.85505776
100Pheochromocytoma (HP:0002666)1.85489030
101Amniotic constriction ring (HP:0009775)1.85255210
102Abnormality of placental membranes (HP:0011409)1.85255210
103Sclerocornea (HP:0000647)1.83336990
104Abnormality of serum amino acid levels (HP:0003112)1.82144349
105Abnormality of the anterior horn cell (HP:0006802)1.81873936
106Degeneration of anterior horn cells (HP:0002398)1.81873936
107White forelock (HP:0002211)1.81851573
108Pancytopenia (HP:0001876)1.81310980
109Nephronophthisis (HP:0000090)1.80489307
110Cleft eyelid (HP:0000625)1.80176798
111Hypomagnesemia (HP:0002917)1.78558549
112Myokymia (HP:0002411)1.78498766
113Rib fusion (HP:0000902)1.78123429
114Anencephaly (HP:0002323)1.77807939
115Pallor (HP:0000980)1.77101270
116Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.76799044
117Anophthalmia (HP:0000528)1.76567423
118Esophageal atresia (HP:0002032)1.74107698
119Delayed CNS myelination (HP:0002188)1.74078426
120Erythroderma (HP:0001019)1.72005332
121Oral leukoplakia (HP:0002745)1.71246370
122Bilateral microphthalmos (HP:0007633)1.70640363
123Abnormality of magnesium homeostasis (HP:0004921)1.69075041
124Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.69011699
125Meckel diverticulum (HP:0002245)1.68003942
126Abnormality of the heme biosynthetic pathway (HP:0010472)1.67911569
127Duplication of thumb phalanx (HP:0009942)1.67793580
128Hypophosphatemic rickets (HP:0004912)1.66924209
129Limb dystonia (HP:0002451)1.65930885
130Vomiting (HP:0002013)1.64922105
131Abnormal respiratory motile cilium physiology (HP:0012261)1.64837740
132Abnormality of reticulocytes (HP:0004312)1.64708200
133Emotional lability (HP:0000712)1.63438081
134Methylmalonic aciduria (HP:0012120)1.63288301
135Megaloblastic anemia (HP:0001889)1.63092031
136Generalized aminoaciduria (HP:0002909)1.61710897
137Abnormality of the corticospinal tract (HP:0002492)1.61153034
138Prolonged neonatal jaundice (HP:0006579)1.60909737
139Hypoplastic left heart (HP:0004383)1.59749234
140Stenosis of the external auditory canal (HP:0000402)1.58792314
141Blindness (HP:0000618)1.56159515
142Anomalous pulmonary venous return (HP:0010772)1.55306233
143Abnormality of macrophages (HP:0004311)1.55206192
144Partial duplication of thumb phalanx (HP:0009944)1.54865729
145Hypoplastic pelvis (HP:0008839)1.54733082
146Paralysis (HP:0003470)1.54058125
147Abnormal ciliary motility (HP:0012262)1.53145261
148Medial flaring of the eyebrow (HP:0010747)1.52075449
149Hyperlipoproteinemia (HP:0010980)1.51933579
150Aplasia/hypoplasia of the uterus (HP:0008684)1.48663172
151Type I transferrin isoform profile (HP:0003642)1.48599220

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK27.05439186
2STK394.53199707
3PBK3.57907049
4OXSR13.23263311
5ZAK2.85634853
6NME22.70277648
7TNIK2.63861542
8STK162.61707223
9MST42.61428424
10SRPK12.35784641
11TAF12.27812849
12EPHB22.24770958
13CDK192.22772737
14WNK42.21489508
15CDC72.21169296
16CASK2.20685541
17BCR2.14214287
18MAPKAPK52.05837143
19MUSK2.00415271
20ARAF1.99369792
21NME11.93175823
22BMPR1B1.91810853
23NUAK11.83211751
24LIMK11.76305983
25PASK1.74427283
26PKN11.63138407
27WNK31.59537053
28GRK71.52895693
29MAP3K121.50464990
30DYRK31.49417043
31PLK31.45326894
32UHMK11.43411936
33CSNK1G31.42480008
34GRK51.40251281
35EPHB11.36622322
36ADRBK21.36060772
37ABL21.35313873
38MYLK1.34269240
39TLK11.34068866
40PIM21.33151047
41VRK11.32243984
42TESK21.30131233
43FGR1.29067887
44INSRR1.21785123
45DYRK21.20215257
46MET1.18532129
47CAMK2B1.13550416
48WEE11.12907523
49BLK1.09350087
50MAP4K21.09281296
51BMPR21.06907096
52NEK61.04223034
53NEK11.03699927
54AURKB1.03367348
55IRAK21.03164550
56CSNK1G11.03008271
57CAMK2D1.00671180
58PLK41.00348304
59CDK80.99765564
60LRRK20.99413286
61TGFBR10.96855362
62BRSK20.96063779
63IRAK40.95844318
64TTK0.93541502
65ROCK20.88041350
66PLK10.86035134
67BUB10.85995509
68EIF2AK30.85948335
69BCKDK0.85877360
70PDK20.84184119
71CSNK1A1L0.84077465
72PNCK0.83616483
73AURKA0.83297860
74CSNK1G20.82932607
75CAMK2G0.81103641
76MAPK130.81071784
77NEK20.77221144
78CAMK2A0.76143391
79MAPK150.76105917
80STK40.75799084
81CSNK2A20.75200576
82OBSCN0.74304746
83ADRBK10.73403211
84TSSK60.69976177
85PINK10.69532232
86MST1R0.69341314
87CSNK2A10.69150994
88RIPK40.68194358
89PRKCQ0.68125877
90RPS6KA50.68037453
91PRKCE0.67586587
92NTRK10.65633877
93PIK3CG0.62476622
94ERBB40.61347136
95PRKCG0.60690987
96FGFR20.60272291
97CLK10.59771096
98MAP3K140.59573774
99CHEK20.57203984
100BRAF0.56455592
101BRSK10.55410747
102MAP2K70.55153884
103IKBKB0.52906770
104CDK140.51390935
105LYN0.50417396
106IRAK10.49672238
107TXK0.48797558
108YES10.48514979
109EIF2AK10.48160148
110PRKACA0.47795505
111WNK10.47745648
112KIT0.47610721
113EPHA40.47606673
114TIE10.46994577
115MAP2K20.46891851
116DAPK30.46529288
117MKNK10.45819363
118IRAK30.45562753
119PIK3CA0.45561467
120GRK10.44910800
121PLK20.44542957
122ATR0.44393528
123ACVR1B0.43820055
124CDK11A0.43387093
125MAPK40.42148726
126PRPF4B0.42043917
127SYK0.41976841
128FES0.41126401
129CDK150.40474885
130DAPK10.40244031
131STK240.39795846
132CDK180.39409472
133ILK0.38843410
134MARK10.38679438
135PRKCD0.38203059
136CSNK1A10.36283276
137PRKG10.35885258
138LCK0.34036313
139PTK2B0.33220859
140TEC0.33198448
141KDR0.33104159
142PAK10.32142497
143CDK30.31677647
144NLK0.30767094
145CSNK1E0.28989502
146CDK70.28771875
147PRKCI0.26001753
148TRIM280.25811883
149CCNB10.25304608
150RPS6KA40.22473954
151FGFR10.22233453

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.38373654
2Parkinsons disease_Homo sapiens_hsa050124.34675319
3Ribosome_Homo sapiens_hsa030103.66871905
4Alzheimers disease_Homo sapiens_hsa050103.37714487
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.33007628
6Protein export_Homo sapiens_hsa030603.24232133
7Steroid biosynthesis_Homo sapiens_hsa001003.16600119
8Fatty acid elongation_Homo sapiens_hsa000623.07189830
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.92558446
10Huntingtons disease_Homo sapiens_hsa050162.87921875
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.85843354
12Proteasome_Homo sapiens_hsa030502.60096410
13Mismatch repair_Homo sapiens_hsa034302.14444418
14Sulfur metabolism_Homo sapiens_hsa009202.12651950
15DNA replication_Homo sapiens_hsa030301.99272071
16RNA polymerase_Homo sapiens_hsa030201.89522669
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.82776556
18Collecting duct acid secretion_Homo sapiens_hsa049661.80246782
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.71681423
20Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.71234419
21Spliceosome_Homo sapiens_hsa030401.66908193
22Cardiac muscle contraction_Homo sapiens_hsa042601.61950281
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.51417471
24Ether lipid metabolism_Homo sapiens_hsa005651.50169676
25Histidine metabolism_Homo sapiens_hsa003401.48952282
26Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.39678908
27Base excision repair_Homo sapiens_hsa034101.37443866
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.33000211
29Glutathione metabolism_Homo sapiens_hsa004801.23884073
30Butanoate metabolism_Homo sapiens_hsa006501.23616829
31Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.22717016
32Peroxisome_Homo sapiens_hsa041461.20641240
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.20421720
34Rheumatoid arthritis_Homo sapiens_hsa053231.19855278
35Vibrio cholerae infection_Homo sapiens_hsa051101.15140446
36RNA degradation_Homo sapiens_hsa030181.13520397
37SNARE interactions in vesicular transport_Homo sapiens_hsa041301.12081582
38Folate biosynthesis_Homo sapiens_hsa007901.09327788
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.09218533
40Tyrosine metabolism_Homo sapiens_hsa003501.07895505
41Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.07102370
42Fanconi anemia pathway_Homo sapiens_hsa034601.06212363
43Linoleic acid metabolism_Homo sapiens_hsa005911.04622957
44Arachidonic acid metabolism_Homo sapiens_hsa005901.01574642
45One carbon pool by folate_Homo sapiens_hsa006701.00927467
46Chemical carcinogenesis_Homo sapiens_hsa052041.00024250
47RNA transport_Homo sapiens_hsa030130.97593641
48Primary bile acid biosynthesis_Homo sapiens_hsa001200.96423673
49Sphingolipid metabolism_Homo sapiens_hsa006000.93655747
50Metabolic pathways_Homo sapiens_hsa011000.92028982
51Arginine and proline metabolism_Homo sapiens_hsa003300.89952082
52Phenylalanine metabolism_Homo sapiens_hsa003600.88819005
53Propanoate metabolism_Homo sapiens_hsa006400.87647186
54Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.87149289
55Steroid hormone biosynthesis_Homo sapiens_hsa001400.85798347
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.82037791
57Phagosome_Homo sapiens_hsa041450.77633357
58Pyrimidine metabolism_Homo sapiens_hsa002400.77591987
59Cyanoamino acid metabolism_Homo sapiens_hsa004600.75543694
60Asthma_Homo sapiens_hsa053100.70849541
61Caffeine metabolism_Homo sapiens_hsa002320.68985261
62Basal cell carcinoma_Homo sapiens_hsa052170.68701214
63Autoimmune thyroid disease_Homo sapiens_hsa053200.67171513
64Serotonergic synapse_Homo sapiens_hsa047260.66527844
65Fat digestion and absorption_Homo sapiens_hsa049750.63994741
66Retinol metabolism_Homo sapiens_hsa008300.63135499
67Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61587019
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61514175
69Pyruvate metabolism_Homo sapiens_hsa006200.60842080
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.59901429
71beta-Alanine metabolism_Homo sapiens_hsa004100.59231756
72Allograft rejection_Homo sapiens_hsa053300.59018591
73Pentose and glucuronate interconversions_Homo sapiens_hsa000400.58607176
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57033081
75Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.56124685
76Graft-versus-host disease_Homo sapiens_hsa053320.54289639
77Carbon metabolism_Homo sapiens_hsa012000.54072791
78Fatty acid metabolism_Homo sapiens_hsa012120.53669105
79Tryptophan metabolism_Homo sapiens_hsa003800.52457778
80Sulfur relay system_Homo sapiens_hsa041220.49384483
81Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.46484647
82Nitrogen metabolism_Homo sapiens_hsa009100.46027949
83Biosynthesis of amino acids_Homo sapiens_hsa012300.45301025
84Complement and coagulation cascades_Homo sapiens_hsa046100.44872405
852-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44324364
86N-Glycan biosynthesis_Homo sapiens_hsa005100.42098070
87Fructose and mannose metabolism_Homo sapiens_hsa000510.40048363
88Selenocompound metabolism_Homo sapiens_hsa004500.39519328
89Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39460322
90Purine metabolism_Homo sapiens_hsa002300.39433278
91Malaria_Homo sapiens_hsa051440.39176208
92Maturity onset diabetes of the young_Homo sapiens_hsa049500.39118105
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38207980
94Cell cycle_Homo sapiens_hsa041100.37743301
95Other glycan degradation_Homo sapiens_hsa005110.37359319
96Vitamin B6 metabolism_Homo sapiens_hsa007500.37002478
97Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36798560
98Phototransduction_Homo sapiens_hsa047440.36547086
99Fatty acid degradation_Homo sapiens_hsa000710.36186219
100Homologous recombination_Homo sapiens_hsa034400.35211794
101Hedgehog signaling pathway_Homo sapiens_hsa043400.35026948
102Staphylococcus aureus infection_Homo sapiens_hsa051500.33438961
103Lysosome_Homo sapiens_hsa041420.31685385
104Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30762586
105Galactose metabolism_Homo sapiens_hsa000520.29158701
106Regulation of autophagy_Homo sapiens_hsa041400.27566873
107Basal transcription factors_Homo sapiens_hsa030220.26518319
108Alcoholism_Homo sapiens_hsa050340.26187622
109Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.25931886
110Drug metabolism - other enzymes_Homo sapiens_hsa009830.23465089
111Axon guidance_Homo sapiens_hsa043600.22738797
112GABAergic synapse_Homo sapiens_hsa047270.21287419
113Pertussis_Homo sapiens_hsa051330.21107558
114African trypanosomiasis_Homo sapiens_hsa051430.20867263
115Starch and sucrose metabolism_Homo sapiens_hsa005000.20117609
116Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.19963402
117Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.19480731
118Glycerolipid metabolism_Homo sapiens_hsa005610.19472477
119Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.19429460
120Vitamin digestion and absorption_Homo sapiens_hsa049770.18938906
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.16014221
122Synaptic vesicle cycle_Homo sapiens_hsa047210.14475375
123Nucleotide excision repair_Homo sapiens_hsa034200.13869562
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.13107246
125Non-homologous end-joining_Homo sapiens_hsa034500.13050064
126Mineral absorption_Homo sapiens_hsa049780.13021172
127PPAR signaling pathway_Homo sapiens_hsa033200.12574960
128Pentose phosphate pathway_Homo sapiens_hsa000300.11749603
129Cysteine and methionine metabolism_Homo sapiens_hsa002700.11627092
130Systemic lupus erythematosus_Homo sapiens_hsa053220.10395004
131Glutamatergic synapse_Homo sapiens_hsa047240.09763137
132Taste transduction_Homo sapiens_hsa047420.08573713

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