TMEM261P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuronal action potential propagation (GO:0019227)7.93532736
2protein maturation by protein folding (GO:0022417)6.31364214
3regulation of short-term neuronal synaptic plasticity (GO:0048172)6.02894665
4negative regulation of calcium ion transport into cytosol (GO:0010523)5.87085957
5pyrimidine nucleobase catabolic process (GO:0006208)5.68205776
6regulation of inhibitory postsynaptic membrane potential (GO:0060080)5.57415627
7postsynaptic membrane organization (GO:0001941)5.54296258
8positive regulation of action potential (GO:0045760)5.36300278
9positive regulation of vesicle fusion (GO:0031340)5.33372638
10cellular response to electrical stimulus (GO:0071257)5.27214379
11synaptic vesicle maturation (GO:0016188)5.22457371
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.10321052
13negative regulation of heart rate (GO:0010459)5.09987041
14sarcoplasmic reticulum calcium ion transport (GO:0070296)4.92965151
15membrane depolarization during action potential (GO:0086010)4.90425652
16behavioral response to ethanol (GO:0048149)4.80419568
17nucleobase catabolic process (GO:0046113)4.70545643
18layer formation in cerebral cortex (GO:0021819)4.58109684
19positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.52120545
20behavioral response to nicotine (GO:0035095)4.46395605
21adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)4.36727908
22cell-cell junction maintenance (GO:0045217)4.33175791
23negative regulation of phosphoprotein phosphatase activity (GO:0032515)4.32879208
24regulation of neuron projection regeneration (GO:0070570)4.31474307
25regulation of axon regeneration (GO:0048679)4.31474307
26inactivation of MAPK activity (GO:0000188)4.27834643
27potassium ion homeostasis (GO:0055075)4.23799207
28collecting duct development (GO:0072044)4.22090071
29trivalent inorganic anion homeostasis (GO:0072506)4.20615928
30phosphate ion homeostasis (GO:0055062)4.20615928
31positive regulation of sodium ion transmembrane transporter activity (GO:2000651)4.19963818
32establishment of mitochondrion localization (GO:0051654)4.17465626
33establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.10658404
34mitochondrion transport along microtubule (GO:0047497)4.10658404
35positive regulation of sodium ion transmembrane transport (GO:1902307)4.10268994
36cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.09733147
37response to redox state (GO:0051775)4.08987441
38negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)4.04544149
39neuron recognition (GO:0008038)3.97581129
40pattern specification involved in kidney development (GO:0061004)3.96498821
41cell junction maintenance (GO:0034331)3.95205806
42positive regulation of dendritic spine development (GO:0060999)3.87850242
43regulation of glycogen (starch) synthase activity (GO:2000465)3.83375288
44response to pheromone (GO:0019236)3.83264446
45positive regulation of microtubule polymerization (GO:0031116)3.82538745
46calcium-mediated signaling using intracellular calcium source (GO:0035584)3.81455192
47cellular anion homeostasis (GO:0030002)3.80028581
48negative regulation of cation channel activity (GO:2001258)3.79871515
49release of sequestered calcium ion into cytosol (GO:0051209)3.78236082
50negative regulation of sequestering of calcium ion (GO:0051283)3.78236082
51regulation of action potential (GO:0098900)3.75579358
52opioid receptor signaling pathway (GO:0038003)3.73970917
53regulation of vesicle fusion (GO:0031338)3.70716878
54regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.63329493
55positive regulation of microtubule polymerization or depolymerization (GO:0031112)3.54229101
56protein export from nucleus (GO:0006611)3.53881892
57short-term memory (GO:0007614)3.52401323
58regulation of sequestering of calcium ion (GO:0051282)3.47965656
59negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.47282314
60negative regulation of calcium ion transmembrane transport (GO:1903170)3.47282314
61presynaptic membrane assembly (GO:0097105)3.46012287
62dopamine receptor signaling pathway (GO:0007212)3.44242042
63protein polyglutamylation (GO:0018095)3.41671034
64positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.38668785
65smooth muscle contraction (GO:0006939)3.37110077
66phenol-containing compound catabolic process (GO:0019336)3.36065212
67regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.35445664
68neuron cell-cell adhesion (GO:0007158)3.35277450
69cell communication by electrical coupling (GO:0010644)3.32476258
70ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043163.29027169
71calcium ion transport into cytosol (GO:0060402)3.28501486
72sympathetic nervous system development (GO:0048485)3.27388320
73cell migration in hindbrain (GO:0021535)3.27142841
74synapse assembly (GO:0007416)3.25081461
75membrane depolarization (GO:0051899)3.24845758
76behavioral defense response (GO:0002209)3.22806286
77behavioral fear response (GO:0001662)3.22806286
78positive regulation of filopodium assembly (GO:0051491)3.19977417
79protein localization to synapse (GO:0035418)3.18350832
80regulation of beta-amyloid formation (GO:1902003)3.16609023
81cytosolic calcium ion transport (GO:0060401)3.16364300
82calcium ion-dependent exocytosis (GO:0017156)3.13544507
83regulation of neurotransmitter uptake (GO:0051580)3.12697641
84auditory behavior (GO:0031223)3.09439432
85response to vitamin E (GO:0033197)3.09137304
86retina layer formation (GO:0010842)3.09034598
87labyrinthine layer development (GO:0060711)3.08928500
88positive regulation of urine volume (GO:0035810)3.08098929
89regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.07748449
90regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.07748449
91membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.04889634
92axonal fasciculation (GO:0007413)3.02797786
93membrane hyperpolarization (GO:0060081)3.01086742
94ionotropic glutamate receptor signaling pathway (GO:0035235)2.93906382
95G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.91639223
96regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.91485093
97presynaptic membrane organization (GO:0097090)2.91421502
98axon extension (GO:0048675)2.90497698
99positive regulation of cellular amide metabolic process (GO:0034250)2.89649506
100negative regulation of adenylate cyclase activity (GO:0007194)2.86347701

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.67569723
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.65461952
3RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.20503395
4ZNF274_21170338_ChIP-Seq_K562_Hela2.90601728
5REST_21632747_ChIP-Seq_MESCs_Mouse2.72278728
6REST_18959480_ChIP-ChIP_MESCs_Mouse2.35916237
7GBX2_23144817_ChIP-Seq_PC3_Human2.33192012
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.25931005
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.25782704
10RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.23886979
11BMI1_23680149_ChIP-Seq_NPCS_Mouse2.17948557
12JARID2_20064375_ChIP-Seq_MESCs_Mouse2.14003426
13EZH2_27294783_Chip-Seq_ESCs_Mouse2.12843810
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.12371079
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.05385480
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.02187223
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.98312876
18SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.98151679
19SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.95153192
20EZH2_27304074_Chip-Seq_ESCs_Mouse1.92974487
21JARID2_20075857_ChIP-Seq_MESCs_Mouse1.87996539
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.86143244
23SUZ12_27294783_Chip-Seq_ESCs_Mouse1.85760394
24ERG_21242973_ChIP-ChIP_JURKAT_Human1.81524641
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.78147740
26DROSHA_22980978_ChIP-Seq_HELA_Human1.77049558
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.71216646
28RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.68458702
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.66117337
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.64931073
31FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.62863038
32RARB_27405468_Chip-Seq_BRAIN_Mouse1.61055083
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.59622325
34FUS_26573619_Chip-Seq_HEK293_Human1.56058572
35TAF15_26573619_Chip-Seq_HEK293_Human1.55046094
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.50433249
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.50013621
38VDR_22108803_ChIP-Seq_LS180_Human1.50013297
39SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.48486223
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47804152
41RNF2_18974828_ChIP-Seq_MESCs_Mouse1.46848546
42EZH2_18974828_ChIP-Seq_MESCs_Mouse1.46848546
43MTF2_20144788_ChIP-Seq_MESCs_Mouse1.41923035
44TP53_16413492_ChIP-PET_HCT116_Human1.41194301
45JUN_21703547_ChIP-Seq_K562_Human1.36519550
46DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35484032
47NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34879820
48RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.30709742
49SMAD4_21799915_ChIP-Seq_A2780_Human1.29730718
50PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29646808
51BCAT_22108803_ChIP-Seq_LS180_Human1.28951491
52RNF2_27304074_Chip-Seq_NSC_Mouse1.28019409
53EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27524253
54PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26268242
55CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25825133
56GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.25256063
57AR_25329375_ChIP-Seq_VCAP_Human1.22946883
58SMAD3_21741376_ChIP-Seq_ESCs_Human1.20177483
59STAT3_23295773_ChIP-Seq_U87_Human1.19951272
60IKZF1_21737484_ChIP-ChIP_HCT116_Human1.19522384
61ETV2_25802403_ChIP-Seq_MESCs_Mouse1.19522034
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18902990
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16995028
64EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.13826159
65KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12975778
66TCF4_23295773_ChIP-Seq_U87_Human1.11646572
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.11639437
68ERA_21632823_ChIP-Seq_H3396_Human1.11418179
69TBL1_22424771_ChIP-Seq_293T_Human1.11017991
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08914962
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.08047321
72VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.06692969
73CTCF_27219007_Chip-Seq_Bcells_Human1.06265137
74POU3F2_20337985_ChIP-ChIP_501MEL_Human1.03584390
75TCF4_22108803_ChIP-Seq_LS180_Human1.02820444
76OCT4_19829295_ChIP-Seq_ESCs_Human0.98697974
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98142457
78MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.97080123
79CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.95974087
80OCT4_20526341_ChIP-Seq_ESCs_Human0.95836523
81MYC_19829295_ChIP-Seq_ESCs_Human0.94957836
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94723692
83CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.92966688
84RUNX2_22187159_ChIP-Seq_PCA_Human0.92117989
85WDR5_24793694_ChIP-Seq_LNCAP_Human0.90512565
86RAC3_21632823_ChIP-Seq_H3396_Human0.90410774
87TAF2_19829295_ChIP-Seq_ESCs_Human0.90279798
88OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.90069612
89NFYA_21822215_ChIP-Seq_K562_Human0.89640207
90TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88947572
91OCT1_27270436_Chip-Seq_PROSTATE_Human0.87380742
92WT1_19549856_ChIP-ChIP_CCG9911_Human0.86609334
93GATA3_21878914_ChIP-Seq_MCF-7_Human0.85828627
94TP53_20018659_ChIP-ChIP_R1E_Mouse0.85777788
95POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.85613450
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85613450
97TRIM28_21343339_ChIP-Seq_HEK293_Human0.85355927
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.85342516
99IRF1_19129219_ChIP-ChIP_H3396_Human0.85192778
100TAL1_26923725_Chip-Seq_HPCs_Mouse0.84824329

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting4.89168565
2MP0004859_abnormal_synaptic_plasticity4.65004126
3MP0003787_abnormal_imprinting4.51830608
4MP0003121_genomic_imprinting4.49952396
5MP0005423_abnormal_somatic_nervous4.30356996
6MP0003123_paternal_imprinting3.45667844
7MP0008877_abnormal_DNA_methylation3.13627793
8MP0001984_abnormal_olfaction3.00592684
9MP0002735_abnormal_chemical_nociception2.97611881
10MP0003635_abnormal_synaptic_transmissio2.63154721
11MP0001968_abnormal_touch/_nociception2.53125891
12MP0000569_abnormal_digit_pigmentation2.51127791
13MP0001440_abnormal_grooming_behavior2.40723071
14MP0006276_abnormal_autonomic_nervous2.23461270
15MP0002736_abnormal_nociception_after2.18383869
16MP0009046_muscle_twitch2.15957011
17MP0009745_abnormal_behavioral_response2.13143485
18MP0000778_abnormal_nervous_system2.12498983
19MP0002734_abnormal_mechanical_nocicepti2.09885101
20MP0002272_abnormal_nervous_system2.06670878
21MP0003646_muscle_fatigue1.94827694
22MP0002572_abnormal_emotion/affect_behav1.93748724
23MP0004142_abnormal_muscle_tone1.91029375
24MP0002063_abnormal_learning/memory/cond1.88234224
25MP0002733_abnormal_thermal_nociception1.78395343
26MP0001529_abnormal_vocalization1.76918667
27MP0004924_abnormal_behavior1.76515122
28MP0005386_behavior/neurological_phenoty1.76515122
29MP0002557_abnormal_social/conspecific_i1.72391591
30MP0001970_abnormal_pain_threshold1.71557710
31MP0001348_abnormal_lacrimal_gland1.71070299
32MP0003880_abnormal_central_pattern1.68193080
33MP0002064_seizures1.67883174
34MP0004133_heterotaxia1.65427887
35MP0001905_abnormal_dopamine_level1.52162778
36MP0002184_abnormal_innervation1.51875352
37MP0004270_analgesia1.50874699
38MP0001986_abnormal_taste_sensitivity1.48872098
39MP0005645_abnormal_hypothalamus_physiol1.48073886
40MP0002067_abnormal_sensory_capabilities1.43300656
41MP0003879_abnormal_hair_cell1.37447725
42MP0005551_abnormal_eye_electrophysiolog1.37023404
43MP0008875_abnormal_xenobiotic_pharmacok1.31060931
44MP0000955_abnormal_spinal_cord1.24723847
45MP0002876_abnormal_thyroid_physiology1.23777733
46MP0000427_abnormal_hair_cycle1.22572608
47MP0004811_abnormal_neuron_physiology1.22236066
48MP0000230_abnormal_systemic_arterial1.21331902
49MP0001486_abnormal_startle_reflex1.12231185
50MP0002837_dystrophic_cardiac_calcinosis1.12010754
51MP0004043_abnormal_pH_regulation1.07685833
52MP0003950_abnormal_plasma_membrane1.07585449
53MP0002102_abnormal_ear_morphology1.07495968
54MP0004742_abnormal_vestibular_system1.06659909
55MP0002638_abnormal_pupillary_reflex1.06523894
56MP0002882_abnormal_neuron_morphology1.06066298
57MP0000579_abnormal_nail_morphology1.02905485
58MP0002693_abnormal_pancreas_physiology1.00856558
59MP0004145_abnormal_muscle_electrophysio1.00616609
60MP0008569_lethality_at_weaning0.99576803
61MP0003329_amyloid_beta_deposits0.97598221
62MP0001501_abnormal_sleep_pattern0.97428111
63MP0005394_taste/olfaction_phenotype0.97142453
64MP0005499_abnormal_olfactory_system0.97142453
65MP0002066_abnormal_motor_capabilities/c0.96460395
66MP0008872_abnormal_physiological_respon0.93559075
67MP0004885_abnormal_endolymph0.89327786
68MP0002909_abnormal_adrenal_gland0.87690005
69MP0001919_abnormal_reproductive_system0.86394587
70MP0002152_abnormal_brain_morphology0.84612750
71MP0003633_abnormal_nervous_system0.81637473
72MP0010386_abnormal_urinary_bladder0.81588810
73MP0005389_reproductive_system_phenotype0.81446709
74MP0002752_abnormal_somatic_nervous0.81394071
75MP0004130_abnormal_muscle_cell0.79762933
76MP0003890_abnormal_embryonic-extraembry0.78983158
77MP0002928_abnormal_bile_duct0.78786616
78MP0005377_hearing/vestibular/ear_phenot0.78765196
79MP0003878_abnormal_ear_physiology0.78765196
80MP0002229_neurodegeneration0.76143391
81MP0004134_abnormal_chest_morphology0.74495016
82MP0005084_abnormal_gallbladder_morpholo0.72862524
83MP0004085_abnormal_heartbeat0.70775646
84MP0008789_abnormal_olfactory_epithelium0.70042469
85MP0006072_abnormal_retinal_apoptosis0.69391038
86MP0003011_delayed_dark_adaptation0.69167850
87MP0001502_abnormal_circadian_rhythm0.68218442
88MP0003631_nervous_system_phenotype0.68122264
89MP0002160_abnormal_reproductive_system0.67927634
90MP0000631_abnormal_neuroendocrine_gland0.66353124
91MP0002069_abnormal_eating/drinking_beha0.65521427
92MP0005195_abnormal_posterior_eye0.64459891
93MP0002163_abnormal_gland_morphology0.61075042
94MP0003698_abnormal_male_reproductive0.60879126
95MP0005365_abnormal_bile_salt0.60654109
96MP0000604_amyloidosis0.60588541
97MP0004484_altered_response_of0.58336144
98MP0000470_abnormal_stomach_morphology0.57627345
99MP0001485_abnormal_pinna_reflex0.56370992
100MP0001963_abnormal_hearing_physiology0.55688573

Predicted human phenotypes

RankGene SetZ-score
1Polyphagia (HP:0002591)5.31653184
2Limb dystonia (HP:0002451)5.16378434
3Thoracic kyphosis (HP:0002942)5.12843545
4Long foot (HP:0001833)4.82631002
5Partial agenesis of the corpus callosum (HP:0001338)4.50656427
6Protruding tongue (HP:0010808)4.39495170
7Rib fusion (HP:0000902)4.32844018
8Hip dysplasia (HP:0001385)4.28830549
9Hyperventilation (HP:0002883)4.16654578
10Exotropia (HP:0000577)3.98909335
11Vertebral arch anomaly (HP:0008438)3.56704685
12Abnormality of the corticospinal tract (HP:0002492)3.47041009
13Abnormality of the middle phalanx of the 5th finger (HP:0004219)3.45799264
14Symphalangism affecting the phalanges of the hand (HP:0009773)3.42181018
15Macroorchidism (HP:0000053)3.39277692
16Abnormality of the thoracic spine (HP:0100711)3.36256425
17Hypochromic microcytic anemia (HP:0004840)3.31665014
18Abnormal eating behavior (HP:0100738)3.21315189
19Epileptic encephalopathy (HP:0200134)3.16967793
20Abnormality of the phalanges of the 5th finger (HP:0004213)3.15104608
21Myokymia (HP:0002411)2.97052219
22Abnormal number of incisors (HP:0011064)2.96154553
23Agitation (HP:0000713)2.95474870
24Narrow forehead (HP:0000341)2.89645682
25Polydipsia (HP:0001959)2.86839846
26Abnormal drinking behavior (HP:0030082)2.86839846
27Oligodontia (HP:0000677)2.84906974
28Infantile muscular hypotonia (HP:0008947)2.84877617
29Gait imbalance (HP:0002141)2.84846794
30Volvulus (HP:0002580)2.82849852
31Nasal speech (HP:0001611)2.82359790
32Esotropia (HP:0000565)2.79739932
33Focal seizures (HP:0007359)2.79690463
34Drooling (HP:0002307)2.79001552
35Shawl scrotum (HP:0000049)2.78261524
36Primary atrial arrhythmia (HP:0001692)2.74417034
37Failure to thrive in infancy (HP:0001531)2.73225868
38Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.66203223
39Broad-based gait (HP:0002136)2.63967898
40Supraventricular tachycardia (HP:0004755)2.60931655
41Abnormality of midbrain morphology (HP:0002418)2.60564475
42Molar tooth sign on MRI (HP:0002419)2.60564475
43Left ventricular hypertrophy (HP:0001712)2.60481117
44Hypochromic anemia (HP:0001931)2.59943884
45Excessive salivation (HP:0003781)2.58784197
46Abnormality of the incisor (HP:0000676)2.54733899
47Poor coordination (HP:0002370)2.51957309
48Supraventricular arrhythmia (HP:0005115)2.50953254
49Homocystinuria (HP:0002156)2.48395633
50Abnormality of homocysteine metabolism (HP:0010919)2.48395633
51Pachygyria (HP:0001302)2.47293322
52Abnormality of the labia minora (HP:0012880)2.46469259
53Hypsarrhythmia (HP:0002521)2.43349484
54EEG with generalized epileptiform discharges (HP:0011198)2.42916449
55Nephronophthisis (HP:0000090)2.41750410
56Natal tooth (HP:0000695)2.37358484
57Epileptiform EEG discharges (HP:0011182)2.36948516
58Aqueductal stenosis (HP:0002410)2.35139426
59Atrial fibrillation (HP:0005110)2.32979192
60Asymmetry of the thorax (HP:0001555)2.28885484
61Limb hypertonia (HP:0002509)2.28491339
62Pancreatic fibrosis (HP:0100732)2.27298474
63Abnormality of the renal cortex (HP:0011035)2.26658824
64Tubular atrophy (HP:0000092)2.24745939
65Aplasia/Hypoplasia of the brainstem (HP:0007362)2.22552157
66Hypoplasia of the brainstem (HP:0002365)2.22552157
67Pointed chin (HP:0000307)2.21876670
68Focal motor seizures (HP:0011153)2.20582027
69Chronic hepatic failure (HP:0100626)2.19901641
70Hyperthyroidism (HP:0000836)2.15582012
71Intellectual disability, severe (HP:0010864)2.14692356
72Lissencephaly (HP:0001339)2.13846575
73Abnormal hair whorl (HP:0010721)2.12212185
74Progressive cerebellar ataxia (HP:0002073)2.11972275
75Tracheomalacia (HP:0002779)2.05913525
76Fetal akinesia sequence (HP:0001989)2.04547898
77Highly arched eyebrow (HP:0002553)2.03733745
78Abnormal biliary tract physiology (HP:0012439)2.02792054
79Bile duct proliferation (HP:0001408)2.02792054
80Sleep apnea (HP:0010535)2.00293602
81Thick eyebrow (HP:0000574)2.00247824
82Inappropriate behavior (HP:0000719)1.99069335
83Torticollis (HP:0000473)1.97957714
84Pancreatic cysts (HP:0001737)1.97358347
85Nephrogenic diabetes insipidus (HP:0009806)1.96416083
86Ulnar claw (HP:0001178)1.94836809
87Congenital primary aphakia (HP:0007707)1.94579602
88Oligomenorrhea (HP:0000876)1.93593443
89Renal cortical cysts (HP:0000803)1.92738573
90Craniofacial dystonia (HP:0012179)1.91842998
91Morphological abnormality of the pyramidal tract (HP:0002062)1.91427579
92X-linked dominant inheritance (HP:0001423)1.89995232
93Polyuria (HP:0000103)1.89720219
94True hermaphroditism (HP:0010459)1.88065401
95Papilledema (HP:0001085)1.87242997
96Fibular aplasia (HP:0002990)1.87202482
97Abnormality of the renal medulla (HP:0100957)1.87100054
98Genetic anticipation (HP:0003743)1.86777888
99Focal dystonia (HP:0004373)1.86286070
100Supernumerary bones of the axial skeleton (HP:0009144)1.81945599

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K97.80544368
2CASK4.69824589
3MARK13.74484425
4CAMK1D3.15522827
5IRAK42.97343045
6MAPK132.70294326
7CAMK1G2.54719269
8MKNK22.32804458
9MINK12.31793160
10WNK32.31680039
11PINK12.19003564
12CAMKK12.14121167
13CAMKK21.98884406
14PRKCH1.97457305
15PHKG11.92597909
16PHKG21.92597909
17DYRK21.92077703
18RPS6KA21.82103626
19TNIK1.66745351
20PAK31.55063330
21ALK1.44485606
22MAP2K71.39594005
23PNCK1.37465395
24SIK21.31891791
25MAP3K41.26394774
26CAMK11.14703610
27PRKCG1.10717303
28ADRBK21.04033040
29GRK11.02179027
30CSNK1E1.01687561
31TYRO31.01127198
32PRKCI1.00670044
33CDK51.00420932
34NTRK21.00067338
35PAK60.99441689
36PKN10.88182326
37DYRK1A0.82178785
38SGK2230.81826862
39SGK4940.81826862
40MARK30.81417579
41MAP4K20.80516768
42UHMK10.78770948
43ICK0.77527536
44SGK20.77116266
45PRKCZ0.76471678
46MKNK10.76314761
47NTRK30.74517564
48RPS6KA60.68788506
49DDR20.68617684
50CAMK40.65528184
51RPS6KL10.65313923
52RPS6KC10.65313923
53CAMK2A0.64127061
54PRKAA10.60813245
55MARK20.60539437
56SGK10.60335338
57STK110.59640652
58WNK40.59502429
59PRKCE0.59336091
60MAPK120.57792120
61TRIB30.55250426
62CDK140.54372445
63FRK0.54271083
64MAP3K110.52246951
65LIMK10.52241191
66TAOK30.51448379
67PRKD20.48270535
68CAMK2D0.47599095
69DAPK20.46923161
70BRSK10.46103092
71GRK70.45466364
72FER0.45119959
73INSRR0.42212197
74PRKACA0.40707693
75CSNK1G20.40039530
76ADRBK10.39716271
77PRKCA0.38574318
78PRKG10.36830492
79PRKCB0.36527414
80CSNK1G30.35822429
81CSNK1A1L0.35743281
82SGK30.35680459
83CAMK2G0.34318035
84RPS6KA30.32889753
85EIF2AK20.32147899
86OXSR10.31633569
87ARAF0.31541388
88RPS6KA10.31221435
89MAPK10.30944470
90STK380.30353027
91PIM20.30169499
92STK160.29342978
93RPS6KB10.29299871
94PRKDC0.28396433
95MATK0.28351670
96CSNK1A10.26453581
97CDC42BPA0.26021610
98CAMK2B0.24837781
99CSNK1G10.22688718
100CDK150.22505453

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.94556981
2Selenocompound metabolism_Homo sapiens_hsa004502.97502149
3Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.91638257
4Synaptic vesicle cycle_Homo sapiens_hsa047212.61506934
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.50297912
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.33705782
7Linoleic acid metabolism_Homo sapiens_hsa005912.32284897
8Cocaine addiction_Homo sapiens_hsa050302.16924504
9Glutamatergic synapse_Homo sapiens_hsa047242.16760551
10Cardiac muscle contraction_Homo sapiens_hsa042602.01601035
11Ether lipid metabolism_Homo sapiens_hsa005652.00444493
12Taste transduction_Homo sapiens_hsa047421.99780766
13Circadian entrainment_Homo sapiens_hsa047131.96506469
14Dopaminergic synapse_Homo sapiens_hsa047281.92180392
15Insulin secretion_Homo sapiens_hsa049111.90640447
16Phototransduction_Homo sapiens_hsa047441.87926093
17Morphine addiction_Homo sapiens_hsa050321.79761784
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.73388415
19Pancreatic secretion_Homo sapiens_hsa049721.70533115
20Axon guidance_Homo sapiens_hsa043601.67372508
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66662819
22Long-term depression_Homo sapiens_hsa047301.63381142
23Amphetamine addiction_Homo sapiens_hsa050311.61441988
24Butanoate metabolism_Homo sapiens_hsa006501.59435320
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.54432672
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.53735514
27GABAergic synapse_Homo sapiens_hsa047271.52987345
28Olfactory transduction_Homo sapiens_hsa047401.38310512
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.34950730
30Parkinsons disease_Homo sapiens_hsa050121.29814009
31Oxidative phosphorylation_Homo sapiens_hsa001901.27972204
32Salivary secretion_Homo sapiens_hsa049701.23799857
33Collecting duct acid secretion_Homo sapiens_hsa049661.21937399
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.19743631
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.18199895
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.17070642
37Dilated cardiomyopathy_Homo sapiens_hsa054141.17046208
38Gastric acid secretion_Homo sapiens_hsa049711.16638982
39Glycerophospholipid metabolism_Homo sapiens_hsa005641.15992480
40Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.15509241
41Calcium signaling pathway_Homo sapiens_hsa040201.14583863
42Primary bile acid biosynthesis_Homo sapiens_hsa001201.14193911
43Oxytocin signaling pathway_Homo sapiens_hsa049211.10079126
44MAPK signaling pathway_Homo sapiens_hsa040101.05203161
45Propanoate metabolism_Homo sapiens_hsa006401.00824807
46Fat digestion and absorption_Homo sapiens_hsa049750.98737922
47Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.96965692
48Aldosterone synthesis and secretion_Homo sapiens_hsa049250.96382040
49Caffeine metabolism_Homo sapiens_hsa002320.96284228
50Long-term potentiation_Homo sapiens_hsa047200.95405159
51Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.95053751
52Alzheimers disease_Homo sapiens_hsa050100.94482613
53Cholinergic synapse_Homo sapiens_hsa047250.93044990
54Ovarian steroidogenesis_Homo sapiens_hsa049130.92496460
55Serotonergic synapse_Homo sapiens_hsa047260.91676118
56Chemical carcinogenesis_Homo sapiens_hsa052040.88839806
57Steroid biosynthesis_Homo sapiens_hsa001000.88321510
58cAMP signaling pathway_Homo sapiens_hsa040240.87466405
59Arginine biosynthesis_Homo sapiens_hsa002200.83993045
60Nitrogen metabolism_Homo sapiens_hsa009100.82882599
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81183672
62Peroxisome_Homo sapiens_hsa041460.80479644
63Fatty acid biosynthesis_Homo sapiens_hsa000610.75709069
64Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74798596
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.74343710
66Renin secretion_Homo sapiens_hsa049240.73320937
67One carbon pool by folate_Homo sapiens_hsa006700.71863422
68Regulation of autophagy_Homo sapiens_hsa041400.67511983
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65666735
70Glycerolipid metabolism_Homo sapiens_hsa005610.65190964
71Protein export_Homo sapiens_hsa030600.61058860
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60805807
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.59847460
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.59120507
75Arachidonic acid metabolism_Homo sapiens_hsa005900.52851042
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.52376475
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.52020730
78Ras signaling pathway_Homo sapiens_hsa040140.50248172
79Lysine degradation_Homo sapiens_hsa003100.50210717
80Phagosome_Homo sapiens_hsa041450.49382313
81Huntingtons disease_Homo sapiens_hsa050160.48511214
82Dorso-ventral axis formation_Homo sapiens_hsa043200.48406516
83Gap junction_Homo sapiens_hsa045400.46735774
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46161949
85Bile secretion_Homo sapiens_hsa049760.44292332
86Thyroid hormone synthesis_Homo sapiens_hsa049180.43644613
87Arginine and proline metabolism_Homo sapiens_hsa003300.42324149
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39686047
89Glucagon signaling pathway_Homo sapiens_hsa049220.39651218
90beta-Alanine metabolism_Homo sapiens_hsa004100.37592976
91Vibrio cholerae infection_Homo sapiens_hsa051100.37186695
92Endocytosis_Homo sapiens_hsa041440.36128270
93ABC transporters_Homo sapiens_hsa020100.34979720
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.33622357
95Tryptophan metabolism_Homo sapiens_hsa003800.32822000
96Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.32065202
97Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30727048
98Tuberculosis_Homo sapiens_hsa051520.30322816
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.29620378
100Fatty acid degradation_Homo sapiens_hsa000710.29498412

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »