TMEM263

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1signal peptide processing (GO:0006465)6.11429801
2maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.64610180
3protein retention in ER lumen (GO:0006621)5.39500917
4COPI coating of Golgi vesicle (GO:0048205)5.29208001
5Golgi transport vesicle coating (GO:0048200)5.29208001
6cartilage development involved in endochondral bone morphogenesis (GO:0060351)5.20047096
7chondrocyte development (GO:0002063)5.10079447
8keratan sulfate catabolic process (GO:0042340)4.54176101
9cullin deneddylation (GO:0010388)4.46475398
10notochord development (GO:0030903)4.45526088
11cell aggregation (GO:0098743)4.45198010
12cartilage condensation (GO:0001502)4.45198010
13ER overload response (GO:0006983)4.39513382
14daunorubicin metabolic process (GO:0044597)4.37538606
15polyketide metabolic process (GO:0030638)4.37538606
16doxorubicin metabolic process (GO:0044598)4.37538606
17embryonic skeletal joint morphogenesis (GO:0060272)4.31517464
18negative regulation of glycogen biosynthetic process (GO:0045719)4.00684810
19regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.95819558
20limb bud formation (GO:0060174)3.93083383
21protein deneddylation (GO:0000338)3.89677588
22collagen fibril organization (GO:0030199)3.79134155
23positive regulation of actin filament depolymerization (GO:0030836)3.76197020
24intraciliary transport (GO:0042073)3.67882534
25COPII vesicle coating (GO:0048208)3.60995158
26nucleotide-sugar biosynthetic process (GO:0009226)3.52753608
27negative regulation of glycogen metabolic process (GO:0070874)3.43582108
28negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.42978597
29negative regulation of dendrite morphogenesis (GO:0050774)3.31580631
30negative regulation of keratinocyte proliferation (GO:0010839)3.30430860
31appendage development (GO:0048736)3.25259462
32limb development (GO:0060173)3.25259462
33negative regulation of axon extension involved in axon guidance (GO:0048843)3.17586259
34regulation of male gonad development (GO:2000018)3.16111174
35ganglion development (GO:0061548)3.14502501
36cartilage development (GO:0051216)3.12802200
37ER to Golgi vesicle-mediated transport (GO:0006888)3.11780179
38chondrocyte proliferation (GO:0035988)3.11474268
39regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.11112376
40zinc ion transport (GO:0006829)3.09067181
41chondroitin sulfate biosynthetic process (GO:0030206)3.07924496
42cellular response to BMP stimulus (GO:0071773)3.04432921
43response to BMP (GO:0071772)3.04432921
44cellular ketone body metabolic process (GO:0046950)3.04183760
45positive regulation of male gonad development (GO:2000020)3.02332199
46mesenchymal-epithelial cell signaling (GO:0060638)3.01519785
47viral protein processing (GO:0019082)3.00029603
48smooth muscle tissue development (GO:0048745)2.97551561
49regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.95330724
50regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.94525092
51neural crest cell development (GO:0014032)2.92523094
52somite development (GO:0061053)2.91315097
53lactate metabolic process (GO:0006089)2.90353593
54lung secretory cell differentiation (GO:0061140)2.89508342
55poly(A)+ mRNA export from nucleus (GO:0016973)2.86806378
56nucleotide transmembrane transport (GO:1901679)2.85345107
57sequestering of extracellular ligand from receptor (GO:0035581)2.82250585
58negative regulation of axon guidance (GO:1902668)2.81169228
59mesenchyme morphogenesis (GO:0072132)2.81134827
60cell adhesion mediated by integrin (GO:0033627)2.78971786
61positive regulation of glycolytic process (GO:0045821)2.78591643
62regulation of glomerulus development (GO:0090192)2.77759330
63ketone body metabolic process (GO:1902224)2.77399022
64regulation of integrin-mediated signaling pathway (GO:2001044)2.77074148
65negative regulation of hormone biosynthetic process (GO:0032353)2.76771398
66regulation of metalloenzyme activity (GO:0048552)2.75744244
67protein heterotrimerization (GO:0070208)2.75301370
68dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.73272840
69nucleotide-sugar metabolic process (GO:0009225)2.72673109
70deoxyribose phosphate biosynthetic process (GO:0046385)2.72506457
712-deoxyribonucleotide biosynthetic process (GO:0009265)2.72506457
72protein peptidyl-prolyl isomerization (GO:0000413)2.71475397
73negative regulation of neurological system process (GO:0031645)2.70069331
74positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)2.68901592
75glomerulus development (GO:0032835)2.68656729
76regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.68092503
77proteoglycan metabolic process (GO:0006029)2.66158260
78type B pancreatic cell proliferation (GO:0044342)2.65998145
79endocardial cushion morphogenesis (GO:0003203)2.65436705
80regulation of cell maturation (GO:1903429)2.64030240
81sequestering of actin monomers (GO:0042989)2.61342496
82metanephric mesenchyme development (GO:0072075)2.61232628
83cell differentiation involved in metanephros development (GO:0072202)2.61031284
84embryonic digit morphogenesis (GO:0042733)2.60632816
85negative regulation of stem cell proliferation (GO:2000647)2.59618627
86extracellular regulation of signal transduction (GO:1900115)2.58384517
87extracellular negative regulation of signal transduction (GO:1900116)2.58384517
88myelin assembly (GO:0032288)2.58060282
89type B pancreatic cell development (GO:0003323)2.57432401
90regulation of hexokinase activity (GO:1903299)2.55069441
91regulation of glucokinase activity (GO:0033131)2.55069441
92negative regulation of myoblast differentiation (GO:0045662)2.54777565
93pericardium development (GO:0060039)2.54185900
94intra-Golgi vesicle-mediated transport (GO:0006891)2.54156523
95negative regulation of hormone metabolic process (GO:0032351)2.53252195
96regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.50728491
97regulation of branching involved in ureteric bud morphogenesis (GO:0090189)2.50683308
98regulation of protein autophosphorylation (GO:0031952)2.50322018
99kidney mesenchyme development (GO:0072074)2.50001612
100negative regulation of mast cell activation (GO:0033004)2.49636201
101chaperone-mediated protein folding (GO:0061077)2.49607716
102platelet dense granule organization (GO:0060155)2.49557983
103dermatan sulfate biosynthetic process (GO:0030208)2.49407111
104mesenchymal cell differentiation involved in renal system development (GO:2001012)2.49054855
105mesenchymal cell differentiation involved in kidney development (GO:0072161)2.49054855
106lipid particle organization (GO:0034389)2.47633917
107regulation of Rac protein signal transduction (GO:0035020)2.44358236
108regulation of type B pancreatic cell apoptotic process (GO:2000674)2.43548726
109protein K11-linked ubiquitination (GO:0070979)2.43153000
110cellular zinc ion homeostasis (GO:0006882)2.42812654
111negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)2.42176127
112cell proliferation involved in kidney development (GO:0072111)2.41711167
113positive regulation of protein autophosphorylation (GO:0031954)2.41334312
114aminoglycoside antibiotic metabolic process (GO:0030647)2.41249255
115mesenchymal cell development (GO:0014031)2.41079084
116inositol phosphate catabolic process (GO:0071545)2.40974086
117positive regulation of extracellular matrix organization (GO:1903055)2.40883639
118branched-chain amino acid catabolic process (GO:0009083)2.40285714
119peptidyl-proline modification (GO:0018208)2.39889302
120keratinocyte development (GO:0003334)2.38594696
121positive regulation of mesonephros development (GO:0061213)2.38493047
122dermatan sulfate metabolic process (GO:0030205)2.37920594
123mesenchymal cell differentiation (GO:0048762)2.37673490
124protein hydroxylation (GO:0018126)2.36368370
125vesicle coating (GO:0006901)2.35661636
126protein localization to microtubule cytoskeleton (GO:0072698)2.35432846
127regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.35132737
128vascular smooth muscle contraction (GO:0014829)2.35080286
129response to redox state (GO:0051775)2.34341324
130cytochrome complex assembly (GO:0017004)2.34289822
131protein complex biogenesis (GO:0070271)2.33254493
132regulation of transforming growth factor beta2 production (GO:0032909)2.33253759
133fibroblast migration (GO:0010761)2.32751741
134protein localization to Golgi apparatus (GO:0034067)2.32582399
135DNA ligation (GO:0006266)2.31940249
136regulation of secondary heart field cardioblast proliferation (GO:0003266)2.31411279
137regulation of cardioblast proliferation (GO:0003264)2.31411279
138response to X-ray (GO:0010165)2.31319681
139DNA double-strand break processing (GO:0000729)2.31255532
140skeletal system development (GO:0001501)2.31175000
141UDP-N-acetylglucosamine metabolic process (GO:0006047)2.31106596
142protein prenylation (GO:0018342)2.29273032
143prenylation (GO:0097354)2.29273032
144negative regulation of complement activation (GO:0045916)2.29157192
145zinc ion homeostasis (GO:0055069)2.29093335
146sequestering of metal ion (GO:0051238)2.26792861
147positive regulation of muscle hypertrophy (GO:0014742)2.26366266
148positive regulation of cardiac muscle hypertrophy (GO:0010613)2.26366266
149cellular response to vitamin D (GO:0071305)2.26228846
150peptidyl-proline hydroxylation (GO:0019511)2.24012790
151zinc ion transmembrane transport (GO:0071577)2.23935206
152protein targeting to Golgi (GO:0000042)2.22474624
153negative chemotaxis (GO:0050919)2.21666653
154peptidyl-cysteine modification (GO:0018198)2.21650495
155negative regulation of protein activation cascade (GO:2000258)2.20942230
156membrane budding (GO:0006900)2.19657133
157substrate adhesion-dependent cell spreading (GO:0034446)2.19164073
158regulation of execution phase of apoptosis (GO:1900117)2.17520354
159cellular response to vitamin (GO:0071295)2.17014466
160positive regulation of glycoprotein metabolic process (GO:1903020)2.16643580
161cilium morphogenesis (GO:0060271)2.14955399
162response to pheromone (GO:0019236)2.14194234
163parental behavior (GO:0060746)2.14043904
164retina vasculature morphogenesis in camera-type eye (GO:0061299)2.13770585
165positive regulation of meiosis (GO:0045836)2.13624874
166positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.13582457
167protein N-linked glycosylation via asparagine (GO:0018279)2.11607496
168establishment of protein localization to Golgi (GO:0072600)2.11595033
169negative regulation of chondrocyte differentiation (GO:0032331)2.11308767
170protein localization to cell surface (GO:0034394)2.11119968
171skin morphogenesis (GO:0043589)2.10583235
172regulation of axon extension involved in axon guidance (GO:0048841)2.10092821
173renal tubule morphogenesis (GO:0061333)2.09798440

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse5.27148330
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.78239803
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.27405660
4GBX2_23144817_ChIP-Seq_PC3_Human2.79555795
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.72694686
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.69587536
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.66098447
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.56568673
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.41467105
10CDX2_19796622_ChIP-Seq_MESCs_Mouse2.37930764
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.34323714
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.33435140
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.26193396
14ELK1_19687146_ChIP-ChIP_HELA_Human2.14784960
15PCGF2_27294783_Chip-Seq_ESCs_Mouse2.14132040
16SALL1_21062744_ChIP-ChIP_HESCs_Human2.08454355
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.05317452
18FUS_26573619_Chip-Seq_HEK293_Human1.94739065
19EWS_26573619_Chip-Seq_HEK293_Human1.94297330
20WT1_19549856_ChIP-ChIP_CCG9911_Human1.92625372
21ZNF274_21170338_ChIP-Seq_K562_Hela1.90620148
22BMI1_23680149_ChIP-Seq_NPCS_Mouse1.81857751
23TAF15_26573619_Chip-Seq_HEK293_Human1.81650521
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.77807553
25IGF1R_20145208_ChIP-Seq_DFB_Human1.76764759
26P300_19829295_ChIP-Seq_ESCs_Human1.72135733
27EP300_21415370_ChIP-Seq_HL-1_Mouse1.71536550
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.68035181
29CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.62598239
30POU5F1_16153702_ChIP-ChIP_HESCs_Human1.60596991
31OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.59928696
32NANOG_18555785_Chip-Seq_ESCs_Mouse1.56572624
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54617012
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.54407371
35DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.53619165
36BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.51556818
37PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.49395501
38EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.47209337
39NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.46997686
40NRF2_20460467_ChIP-Seq_MEFs_Mouse1.46997686
41E2F1_18555785_Chip-Seq_ESCs_Mouse1.46782392
42SUZ12_27294783_Chip-Seq_NPCs_Mouse1.46670477
43P53_22387025_ChIP-Seq_ESCs_Mouse1.46215976
44SALL4_18804426_ChIP-ChIP_XEN_Mouse1.46047372
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.45410717
46STAT3_18555785_Chip-Seq_ESCs_Mouse1.44886664
47TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44337392
48TP63_19390658_ChIP-ChIP_HaCaT_Human1.44311258
49ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.43600744
50PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.43456656
51TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.42920358
52FOXM1_26456572_ChIP-Seq_MCF-7_Human1.42124786
53EZH2_27294783_Chip-Seq_NPCs_Mouse1.41534812
54MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.40779595
55SMAD4_21799915_ChIP-Seq_A2780_Human1.40725432
56RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.40367143
57EST1_17652178_ChIP-ChIP_JURKAT_Human1.39362509
58HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.39123571
59CJUN_26792858_Chip-Seq_BT549_Human1.37256202
60NFE2_27457419_Chip-Seq_LIVER_Mouse1.36541745
61HIF1A_21447827_ChIP-Seq_MCF-7_Human1.35893611
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35628834
63TP53_18474530_ChIP-ChIP_U2OS_Human1.34973332
64CBX2_27304074_Chip-Seq_ESCs_Mouse1.34900324
65CDX2_22108803_ChIP-Seq_LS180_Human1.34152989
66KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33484465
67SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33476037
68AR_25329375_ChIP-Seq_VCAP_Human1.33356903
69SUZ12_18555785_Chip-Seq_ESCs_Mouse1.32517393
70AR_21572438_ChIP-Seq_LNCaP_Human1.32358125
71TP53_16413492_ChIP-PET_HCT116_Human1.31463771
72CTBP2_25329375_ChIP-Seq_LNCAP_Human1.31339104
73TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.30351299
74NMYC_18555785_Chip-Seq_ESCs_Mouse1.30296417
75CMYC_18555785_Chip-Seq_ESCs_Mouse1.27086529
76P300_18555785_Chip-Seq_ESCs_Mouse1.26486136
77BCAT_22108803_ChIP-Seq_LS180_Human1.25724203
78ER_23166858_ChIP-Seq_MCF-7_Human1.25557091
79FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.25532950
80MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.25520318
81TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.25271129
82SRF_21415370_ChIP-Seq_HL-1_Mouse1.24505944
83VDR_22108803_ChIP-Seq_LS180_Human1.24307564
84CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23414774
85AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22831747
86SOX2_18555785_Chip-Seq_ESCs_Mouse1.22406590
87E2F7_22180533_ChIP-Seq_HELA_Human1.21992683
88TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.21647853
89CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21413855
90PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.20624156
91EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.19075493
92BRD4_25478319_ChIP-Seq_HGPS_Human1.19063870
93PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18993261
94FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18584707
95YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18173896
96PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.16927064
97RNF2_27304074_Chip-Seq_NSC_Mouse1.14382304
98CBP_20019798_ChIP-Seq_JUKART_Human1.13989095
99IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.13989095
100CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13966758
101SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.12897267
102JUN_21703547_ChIP-Seq_K562_Human1.12323830
103EED_16625203_ChIP-ChIP_MESCs_Mouse1.11911353
104UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08376899
105NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08133539
106ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07898044
107TCF4_22108803_ChIP-Seq_LS180_Human1.07156704
108JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.06855748
109SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.06821696
110TCF4_23295773_ChIP-Seq_U87_Human1.05858954
111PCGF2_27294783_Chip-Seq_NPCs_Mouse1.05583930
112NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04716812
113ZFX_18555785_Chip-Seq_ESCs_Mouse1.04073063
114SMAD3_21741376_ChIP-Seq_EPCs_Human1.03908808
115GF1B_26923725_Chip-Seq_HPCs_Mouse1.03300628
116NANOG_19829295_ChIP-Seq_ESCs_Human1.02224758
117SOX2_19829295_ChIP-Seq_ESCs_Human1.02224758
118HOXB4_20404135_ChIP-ChIP_EML_Mouse1.02217978
119EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01515729
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01384592
121PADI4_21655091_ChIP-ChIP_MCF-7_Human1.01377894
122KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.01324844
123OCT4_18555785_Chip-Seq_ESCs_Mouse1.01262052
124STAT3_23295773_ChIP-Seq_U87_Human1.00135684
125FLI1_21867929_ChIP-Seq_TH2_Mouse1.00098919
126RUNX1_27457419_Chip-Seq_LIVER_Mouse0.99744981
127SOX2_20726797_ChIP-Seq_SW620_Human0.99271538
128KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98630936
129HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.98111253
130ESR1_21235772_ChIP-Seq_MCF-7_Human0.96666388
131CRX_20693478_ChIP-Seq_RETINA_Mouse0.96375531
132GATA1_22025678_ChIP-Seq_K562_Human0.96372577
133SMAD1_18555785_Chip-Seq_ESCs_Mouse0.96288033
134KLF4_18555785_Chip-Seq_ESCs_Mouse0.95967505
135TBX3_20139965_ChIP-Seq_MESCs_Mouse0.95496386
136TBX3_20139965_ChIP-Seq_ESCs_Mouse0.95454140
137GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95380159
138ARNT_22903824_ChIP-Seq_MCF-7_Human0.95232609
139SMAD4_21741376_ChIP-Seq_EPCs_Human0.94725092

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology4.26645944
2MP0009780_abnormal_chondrocyte_physiolo3.34086857
3MP0009250_abnormal_appendicular_skeleto2.97683712
4MP0008438_abnormal_cutaneous_collagen2.90037196
5MP0002282_abnormal_trachea_morphology2.83113857
6MP0004134_abnormal_chest_morphology2.59209341
7MP0003122_maternal_imprinting2.51170458
8MP0003123_paternal_imprinting2.49799066
9MP0003787_abnormal_imprinting2.44030062
10MP0005646_abnormal_pituitary_gland2.37513700
11MP0001188_hyperpigmentation2.32480104
12MP0000163_abnormal_cartilage_morphology2.24869016
13MP0001542_abnormal_bone_strength2.20453970
14MP0003121_genomic_imprinting2.18435152
15MP0000049_abnormal_middle_ear2.11465070
16MP0002933_joint_inflammation2.06688500
17MP0005508_abnormal_skeleton_morphology2.06109714
18MP0000566_synostosis2.03131951
19MP0002877_abnormal_melanocyte_morpholog2.02830850
20MP0009697_abnormal_copulation2.02084630
21MP0002163_abnormal_gland_morphology1.99217327
22MP0005257_abnormal_intraocular_pressure1.97215395
23MP0001986_abnormal_taste_sensitivity1.96302715
24MP0010234_abnormal_vibrissa_follicle1.93783377
25MP0002009_preneoplasia1.88413200
26MP0002115_abnormal_skeleton_extremities1.85480828
27MP0005623_abnormal_meninges_morphology1.84725708
28MP0000678_abnormal_parathyroid_gland1.83406236
29MP0000516_abnormal_urinary_system1.77472708
30MP0005367_renal/urinary_system_phenotyp1.77472708
31MP0005275_abnormal_skin_tensile1.77300536
32MP0010030_abnormal_orbit_morphology1.76534474
33MP0003755_abnormal_palate_morphology1.74031386
34MP0010386_abnormal_urinary_bladder1.72732163
35MP0003942_abnormal_urinary_system1.69619302
36MP0002102_abnormal_ear_morphology1.62948076
37MP0002295_abnormal_pulmonary_circulatio1.60240965
38MP0002109_abnormal_limb_morphology1.60204020
39MP0002876_abnormal_thyroid_physiology1.58829569
40MP0002837_dystrophic_cardiac_calcinosis1.58707229
41MP0005171_absent_coat_pigmentation1.57537970
42MP0002113_abnormal_skeleton_development1.57323345
43MP0001177_atelectasis1.56920621
44MP0010352_gastrointestinal_tract_polyps1.53382008
45MP0009053_abnormal_anal_canal1.50127658
46MP0003385_abnormal_body_wall1.44594809
47MP0003283_abnormal_digestive_organ1.44137288
48MP0001299_abnormal_eye_distance/1.44003255
49MP0006072_abnormal_retinal_apoptosis1.43776449
50MP0002896_abnormal_bone_mineralization1.41723135
51MP0002249_abnormal_larynx_morphology1.40293296
52MP0005390_skeleton_phenotype1.38657281
53MP0001879_abnormal_lymphatic_vessel1.35219396
54MP0005379_endocrine/exocrine_gland_phen1.35103455
55MP0006054_spinal_hemorrhage1.34005108
56MP0002116_abnormal_craniofacial_bone1.31941275
57MP0000372_irregular_coat_pigmentation1.31717728
58MP0000003_abnormal_adipose_tissue1.30993904
59MP0002751_abnormal_autonomic_nervous1.30417885
60MP0004272_abnormal_basement_membrane1.29908898
61MP0003941_abnormal_skin_development1.28800571
62MP0003943_abnormal_hepatobiliary_system1.25297157
63MP0009384_cardiac_valve_regurgitation1.24635440
64MP0002108_abnormal_muscle_morphology1.24061421
65MP0002233_abnormal_nose_morphology1.23946993
66MP0005084_abnormal_gallbladder_morpholo1.22512030
67MP0005187_abnormal_penis_morphology1.22465464
68MP0000762_abnormal_tongue_morphology1.22157203
69MP0003279_aneurysm1.22116860
70MP0000015_abnormal_ear_pigmentation1.21105920
71MP0002938_white_spotting1.20989785
72MP0003183_abnormal_peptide_metabolism1.18627377
73MP0000013_abnormal_adipose_tissue1.18546944
74MP0000462_abnormal_digestive_system1.17738211
75MP0001243_abnormal_dermal_layer1.17444494
76MP0008007_abnormal_cellular_replicative1.17260791
77MP0000427_abnormal_hair_cycle1.17237806
78MP0008775_abnormal_heart_ventricle1.16928184
79MP0000767_abnormal_smooth_muscle1.16818924
80MP0004782_abnormal_surfactant_physiolog1.16750892
81MP0000681_abnormal_thyroid_gland1.13338837
82MP0000613_abnormal_salivary_gland1.13246626
83MP0002909_abnormal_adrenal_gland1.12889523
84MP0003868_abnormal_feces_composition1.11642174
85MP0001919_abnormal_reproductive_system1.11160212
86MP0001270_distended_abdomen1.11136023
87MP0003937_abnormal_limbs/digits/tail_de1.09861047
88MP0003935_abnormal_craniofacial_develop1.09734594
89MP0003119_abnormal_digestive_system1.08181912
90MP0003950_abnormal_plasma_membrane1.08070131
91MP0008789_abnormal_olfactory_epithelium1.07143554
92MP0002234_abnormal_pharynx_morphology1.06572674
93MP0003252_abnormal_bile_duct1.05257377
94MP0000569_abnormal_digit_pigmentation1.04699982
95MP0003566_abnormal_cell_adhesion1.04636202
96MP0001944_abnormal_pancreas_morphology1.03273057
97MP0000639_abnormal_adrenal_gland1.01745891
98MP0003195_calcinosis1.01119686
99MP0002168_other_aberrant_phenotype1.00840766
100MP0005248_abnormal_Harderian_gland1.00630125
101MP0002114_abnormal_axial_skeleton1.00514422
102MP0002160_abnormal_reproductive_system0.98326133
103MP0003795_abnormal_bone_structure0.98237051
104MP0003786_premature_aging0.97184489
105MP0005220_abnormal_exocrine_pancreas0.97135007
106MP0000534_abnormal_ureter_morphology0.97098932
107MP0000432_abnormal_head_morphology0.97040250
108MP0002254_reproductive_system_inflammat0.96241903
109MP0001661_extended_life_span0.95665491
110MP0005253_abnormal_eye_physiology0.94753004
111MP0001286_abnormal_eye_development0.93596652
112MP0002177_abnormal_outer_ear0.93428078
113MP0000631_abnormal_neuroendocrine_gland0.92650464
114MP0002090_abnormal_vision0.92294368
115MP0001756_abnormal_urination0.91917071
116MP0005645_abnormal_hypothalamus_physiol0.91222527
117MP0005389_reproductive_system_phenotype0.89871509
118MP0004215_abnormal_myocardial_fiber0.89793114
119MP0004084_abnormal_cardiac_muscle0.89608302
120MP0001984_abnormal_olfaction0.89298452
121MP0000647_abnormal_sebaceous_gland0.88378184
122MP0001958_emphysema0.88105855
123MP0008058_abnormal_DNA_repair0.86444141
124MP0005332_abnormal_amino_acid0.86259903
125MP0010368_abnormal_lymphatic_system0.85123138
126MP0002089_abnormal_postnatal_growth/wei0.85016750
127MP0005408_hypopigmentation0.83736068
128MP0002928_abnormal_bile_duct0.82162293
129MP0004133_heterotaxia0.80122218
130MP0003115_abnormal_respiratory_system0.80121803
131MP0010678_abnormal_skin_adnexa0.79931920
132MP0002932_abnormal_joint_morphology0.79431558
133MP0005023_abnormal_wound_healing0.78867070
134MP0002060_abnormal_skin_morphology0.78319940
135MP0006292_abnormal_olfactory_placode0.77496591
136MP0010329_abnormal_lipoprotein_level0.75828344
137MP0002111_abnormal_tail_morphology0.74633056
138MP0000538_abnormal_urinary_bladder0.74363622
139MP0001119_abnormal_female_reproductive0.72228123
140MP0005551_abnormal_eye_electrophysiolog0.71070091
141MP0005388_respiratory_system_phenotype0.70824166
142MP0002133_abnormal_respiratory_system0.70824166
143MP0005085_abnormal_gallbladder_physiolo0.67118341
144MP0004085_abnormal_heartbeat0.66465131
145MP0003186_abnormal_redox_activity0.65521573
146MP0000749_muscle_degeneration0.63773240

Predicted human phenotypes

RankGene SetZ-score
1Irregular epiphyses (HP:0010582)7.01440163
2Epiphyseal dysplasia (HP:0002656)6.24975655
3Vitreoretinal degeneration (HP:0000655)6.03991327
4Premature rupture of membranes (HP:0001788)5.08950211
5Flat capital femoral epiphysis (HP:0003370)4.97946885
6Hypoplastic ischia (HP:0003175)4.40695745
7Cupped ribs (HP:0000887)4.31292587
8Abnormality of the ischium (HP:0003174)4.17692712
9Abnormal tarsal ossification (HP:0008369)4.00883260
10Abnormality of incisor morphology (HP:0011063)3.91778115
11Small epiphyses (HP:0010585)3.85067552
12Neonatal short-limb short stature (HP:0008921)3.75450720
13Aortic dissection (HP:0002647)3.68872747
14Abnormality of femoral epiphyses (HP:0006499)3.61148585
15Abnormality involving the epiphyses of the lower limbs (HP:0006500)3.61148585
16Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.51907235
17Genu varum (HP:0002970)3.50381232
18Protrusio acetabuli (HP:0003179)3.45160904
19Abnormal foot bone ossification (HP:0010675)3.42749353
20Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.34979837
21Absent epiphyses (HP:0010577)3.34979837
22Soft skin (HP:0000977)3.29605551
23Abnormality of the epiphysis of the femoral head (HP:0010574)3.28441774
24Delayed epiphyseal ossification (HP:0002663)3.27824138
25Delayed gross motor development (HP:0002194)3.24185695
26Metaphyseal dysplasia (HP:0100255)3.21373014
27Abnormality of the femoral head (HP:0003368)3.20041564
28Abnormality of the vertebral endplates (HP:0005106)3.13772653
29Flattened epiphyses (HP:0003071)3.12443393
30Arthropathy (HP:0003040)3.12186012
31Mild short stature (HP:0003502)3.04064401
32Vascular tortuosity (HP:0004948)3.01370297
33Irregular vertebral endplates (HP:0003301)2.97043009
34Fibular hypoplasia (HP:0003038)2.93396099
35Cervical subluxation (HP:0003308)2.92443297
36Long clavicles (HP:0000890)2.84135284
37Short femoral neck (HP:0100864)2.79949430
38Beaking of vertebral bodies (HP:0004568)2.77924901
39Flat acetabular roof (HP:0003180)2.74048435
40Arterial tortuosity (HP:0005116)2.72907889
41Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.71487931
42Metaphyseal cupping (HP:0003021)2.69977414
43Metaphyseal irregularity (HP:0003025)2.69041396
44Abnormality of the proximal phalanges of the hand (HP:0009834)2.68488690
45Osteoarthritis (HP:0002758)2.67945262
46Cardiovascular calcification (HP:0011915)2.59867374
47Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.57400002
48Hyperinsulinemic hypoglycemia (HP:0000825)2.55501689
49Hypoglycemic coma (HP:0001325)2.53581316
50Ketoacidosis (HP:0001993)2.52758368
51Abnormality of the phalanges of the 5th finger (HP:0004213)2.50255821
52True hermaphroditism (HP:0010459)2.48116745
53Hepatoblastoma (HP:0002884)2.47399934
54Absent frontal sinuses (HP:0002688)2.45991350
55Hypoglycemic seizures (HP:0002173)2.43867144
56Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.43751773
57Mesomelia (HP:0003027)2.41939520
58Hyperglycemia (HP:0003074)2.41819660
59Abnormality of the phalanges of the 2nd finger (HP:0009541)2.38760207
60Cutaneous melanoma (HP:0012056)2.38519921
61Patent foramen ovale (HP:0001655)2.37242756
62Abnormal hair whorl (HP:0010721)2.35941797
63Increased corneal curvature (HP:0100692)2.35153874
64Keratoconus (HP:0000563)2.35153874
65Abnormality of the pubic bones (HP:0003172)2.34411992
66Aortic aneurysm (HP:0004942)2.33445461
67Unilateral renal agenesis (HP:0000122)2.32148767
68Platyspondyly (HP:0000926)2.23504626
69Stillbirth (HP:0003826)2.22003175
70Abnormality of the frontal sinuses (HP:0002687)2.19743283
71Hypothermia (HP:0002045)2.18925584
72Thoracolumbar scoliosis (HP:0002944)2.18660356
73Abnormal pancreas size (HP:0012094)2.18099857
74Barrel-shaped chest (HP:0001552)2.17143413
75Disproportionate short-trunk short stature (HP:0003521)2.16966811
76Atrophic scars (HP:0001075)2.14875973
77Methylmalonic acidemia (HP:0002912)2.13765804
78Abnormality of carpal bone ossification (HP:0006257)2.12727878
79Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.11394552
80Spondylolisthesis (HP:0003302)2.10828252
81Hemiparesis (HP:0001269)2.10768076
82Hypokinesia (HP:0002375)2.10596526
83Thin ribs (HP:0000883)2.10487772
84Abnormality of the nasal septum (HP:0000419)2.10418185
85Micromelia (HP:0002983)2.09331966
86Syringomyelia (HP:0003396)2.08785613
87Spinal cord lesions (HP:0100561)2.08785613
88Abnormal vertebral ossification (HP:0100569)2.08166624
89Congenital primary aphakia (HP:0007707)2.07239356
90Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.04734017
91Vertebral hypoplasia (HP:0008417)2.04734017
92Abnormality of proline metabolism (HP:0010907)2.03756924
93Hydroxyprolinuria (HP:0003080)2.03756924
94Wormian bones (HP:0002645)2.03215894
95Vascular calcification (HP:0004934)2.03099216
96Abnormality of the wing of the ilium (HP:0011867)2.01761522
97Mitral stenosis (HP:0001718)2.01065510
98Abnormality of endocrine pancreas physiology (HP:0012093)2.00960268
99Abnormality of the pancreatic islet cells (HP:0006476)2.00960268
100Decreased skull ossification (HP:0004331)2.00539530
101Protuberant abdomen (HP:0001538)2.00460930
102Aplasia/Hypoplasia of the fibula (HP:0006492)1.99647610
103Deep philtrum (HP:0002002)1.99385859
104Tracheomalacia (HP:0002779)1.98598536
105Genu recurvatum (HP:0002816)1.98306416
106Adrenal hypoplasia (HP:0000835)1.95632344
107Abnormality of vitamin B metabolism (HP:0004340)1.95048436
108Enlarged epiphyses (HP:0010580)1.93967496
109Broad phalanx (HP:0006009)1.93904240
110Bladder diverticulum (HP:0000015)1.93521562
111Gait imbalance (HP:0002141)1.92424669
112Neoplasm of the adrenal cortex (HP:0100641)1.91732258
113Aplasia/Hypoplasia of the tongue (HP:0010295)1.91432941
114Nephrogenic diabetes insipidus (HP:0009806)1.91084285
115Broad long bones (HP:0005622)1.90399263
116Coxa vara (HP:0002812)1.89920303
117Hypoplastic ilia (HP:0000946)1.88990834
118Thyroiditis (HP:0100646)1.86510610
119Large for gestational age (HP:0001520)1.84970244
120Sprengel anomaly (HP:0000912)1.84859190
121Enlarged penis (HP:0000040)1.84477521
122Thyroid carcinoma (HP:0002890)1.83830611
123Follicular hyperkeratosis (HP:0007502)1.83546964
124Hypoplastic iliac wings (HP:0002866)1.83037768
125Microglossia (HP:0000171)1.82897925
126Aplasia/hypoplasia of the femur (HP:0005613)1.82773603
127Aplasia/Hypoplasia of the scapulae (HP:0006713)1.82311611
128Hypoplastic scapulae (HP:0000882)1.82311611
129Ankle contracture (HP:0006466)1.80175089
130Hypobetalipoproteinemia (HP:0003563)1.79274072
131Enlarged kidneys (HP:0000105)1.79170584
132Papillary thyroid carcinoma (HP:0002895)1.78478689
133Abnormal delivery (HP:0001787)1.78455233
134Genital tract atresia (HP:0001827)1.77451994
135Hypoplasia of the capital femoral epiphysis (HP:0003090)1.77357425
136Abnormality of the incisor (HP:0000676)1.77111880
137Glossoptosis (HP:0000162)1.76813159
138Tubular atrophy (HP:0000092)1.75438427
139Abnormality of dentin (HP:0010299)1.74698745
140Bowel diverticulosis (HP:0005222)1.74595100
141Hyperextensible skin (HP:0000974)1.73248228
14211 pairs of ribs (HP:0000878)1.73212074
143Buphthalmos (HP:0000557)1.72815989
144Medial flaring of the eyebrow (HP:0010747)1.72369681
145Embryonal renal neoplasm (HP:0011794)1.72069411
146Congenital glaucoma (HP:0001087)1.72032277
147Pancreatic fibrosis (HP:0100732)1.71498213
148Short 5th finger (HP:0009237)1.71333069
149Asymmetry of the thorax (HP:0001555)1.69960021
150Hypoplasia of the odontoid process (HP:0003311)1.69493395
151Abnormality of the fibula (HP:0002991)1.69424905
152Increased serum pyruvate (HP:0003542)1.68565905
153Abnormality of glycolysis (HP:0004366)1.68278136
154Hamartoma of the eye (HP:0010568)1.67726444
155Renal cortical cysts (HP:0000803)1.66998029
156Overgrowth (HP:0001548)1.66724231
157Abnormality of aromatic amino acid family metabolism (HP:0004338)1.66204363
158Pancreatic islet-cell hyperplasia (HP:0004510)1.65770542
159Aplasia/Hypoplasia of the lens (HP:0008063)1.65041092
160Infantile muscular hypotonia (HP:0008947)1.64401225
161Intrahepatic cholestasis (HP:0001406)1.63619610
162Pulmonic stenosis (HP:0001642)1.61291918
163Coronal craniosynostosis (HP:0004440)1.61137502
164Pancreatic cysts (HP:0001737)1.60952738
165Proximal tubulopathy (HP:0000114)1.59085500
166Vaginal atresia (HP:0000148)1.58019181
167Tongue fasciculations (HP:0001308)1.57619047
168Hypoplasia of the uterus (HP:0000013)1.57557195
169Occipital encephalocele (HP:0002085)1.56707874
170Hematochezia (HP:0002573)1.56060831
171Intestinal atresia (HP:0011100)1.55891185
172Aplasia/hypoplasia of the uterus (HP:0008684)1.55872409
173Glucose intolerance (HP:0000833)1.54331218
174Striae distensae (HP:0001065)1.54262753
175Hypolipoproteinemia (HP:0010981)1.52380230
176Abnormality of the calf musculature (HP:0001430)1.51360140
177Entropion (HP:0000621)1.51306133
178Bradycardia (HP:0001662)1.51238169
179Symptomatic seizures (HP:0011145)1.50766003
180Fragile skin (HP:0001030)1.50375064
181Short tibia (HP:0005736)1.50225520

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB34.70785684
2CASK3.42521435
3AKT33.25093365
4STK38L2.93627151
5SIK32.92546618
6FRK2.90863980
7MKNK22.67100010
8BMPR22.65908231
9ZAK2.52493125
10TRIM282.47579483
11PLK22.28928427
12MAP4K22.20712446
13STK242.18376745
14SGK22.10003803
15MKNK12.07350373
16PRPF4B1.98623639
17FGFR21.98330407
18EIF2AK11.91691528
19MAP3K31.86653219
20NUAK11.83091141
21PLK31.72832038
22EIF2AK31.71454654
23BCR1.70830687
24PRKD31.69695834
25NEK61.67010020
26TRPM71.64036831
27DDR21.63306836
28PAK31.60242878
29ACVR1B1.50783913
30MST41.43657458
31GRK11.42354525
32BMPR1B1.40183228
33CDK81.39497432
34PLK41.36048752
35STK391.35873041
36SGK4941.34235178
37SGK2231.34235178
38NEK91.29193208
39YES11.28689163
40SRPK11.24772787
41VRK11.24083930
42PRKG21.22966559
43MET1.21309316
44FLT31.20529950
45CSNK1G11.19323293
46PTK21.16548975
47NEK11.16393914
48MAPK131.15443610
49INSRR1.13512630
50NME11.11855073
51TAOK21.11645552
52SGK31.10822386
53MAP3K141.10779595
54BRSK21.09829194
55MAP2K71.09139275
56MAP3K41.09038442
57EIF2AK21.08070476
58PASK1.02065336
59PNCK1.00816363
60ERBB40.97974413
61PINK10.96905636
62CSNK1G30.94937906
63MYLK0.90994058
64IRAK40.90926208
65CSNK1G20.90347595
66PIK3CA0.88531813
67TSSK60.88201217
68CSNK1A1L0.87445037
69WNK40.87396027
70PTK2B0.83756640
71RPS6KB10.83575004
72BUB10.82400923
73PHKG20.81063033
74PHKG10.81063033
75ADRBK20.80093418
76LIMK10.80082195
77PDGFRA0.79870754
78STK160.76720910
79PAK20.75746040
80WNK30.75366384
81LMTK20.75257909
82STK30.74585171
83CAMK2D0.72282668
84FGFR10.71413588
85DYRK1A0.70235380
86IRAK30.70049298
87ROCK20.69745828
88TNK20.68514695
89BRD40.67948490
90FGFR30.67810175
91TGFBR20.67661598
92ILK0.67259136
93CHUK0.64462840
94PRKCE0.63479906
95MAP3K20.62279534
96PIK3CG0.60800870
97CDC42BPA0.58912135
98RPS6KL10.58574298
99RPS6KC10.58574298
100BRAF0.56708864
101LATS10.56173028
102STK380.55862344
103WEE10.55235020
104RPS6KA60.54681426
105SCYL20.54201971
106MAPKAPK30.54023792
107FER0.52850440
108CDK30.52760167
109GSK3A0.51075051
110RPS6KA20.48538770
111EPHA30.47676688
112MAP2K10.47541366
113TESK10.47510390
114PIM20.46369007
115NLK0.45478207
116TXK0.43856226
117MAPK70.43173649
118PRKCH0.41987276
119NTRK30.41479788
120TEC0.40241701
121PAK40.38959120
122MUSK0.37942385
123EPHB20.37739125
124PKN20.37585124
125DMPK0.37582183
126BRSK10.37229084
127CAMKK20.37077210
128CAMK2A0.35894999
129PRKD20.35438791
130ADRBK10.35372490
131ABL10.33226433
132CSNK2A10.31797367
133PRKCI0.31311284
134PRKCG0.31046701
135MAP3K120.31003721
136TAF10.30902023
137ROCK10.30610327
138ATM0.29612827
139RPS6KA40.26907666
140PRKG10.26725185
141TGFBR10.26074386
142MAPK30.24634900
143CLK10.24471055
144TNIK0.23832566
145GRK70.23575041
146SGK10.22431030
147PLK10.21718018
148PDK20.20634294

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030605.86852304
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.66316117
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.48264473
4SNARE interactions in vesicular transport_Homo sapiens_hsa041302.50947989
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.47804320
6Butanoate metabolism_Homo sapiens_hsa006502.43217290
7Propanoate metabolism_Homo sapiens_hsa006402.41733475
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.31679344
9ECM-receptor interaction_Homo sapiens_hsa045122.12306676
10Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.09951606
11Vibrio cholerae infection_Homo sapiens_hsa051102.05204401
12Basal transcription factors_Homo sapiens_hsa030222.01518187
13Protein digestion and absorption_Homo sapiens_hsa049741.97998913
14Sulfur metabolism_Homo sapiens_hsa009201.96143410
15Fatty acid elongation_Homo sapiens_hsa000621.90414049
16Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.87047209
17Vitamin B6 metabolism_Homo sapiens_hsa007501.84486173
18Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.74583752
19Non-homologous end-joining_Homo sapiens_hsa034501.68290094
20RNA degradation_Homo sapiens_hsa030181.53872462
21RNA polymerase_Homo sapiens_hsa030201.52384442
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.52166454
23Proteasome_Homo sapiens_hsa030501.51888850
24Primary bile acid biosynthesis_Homo sapiens_hsa001201.49603540
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.49553193
26Nucleotide excision repair_Homo sapiens_hsa034201.49267832
27Base excision repair_Homo sapiens_hsa034101.48958545
28N-Glycan biosynthesis_Homo sapiens_hsa005101.48396914
29TGF-beta signaling pathway_Homo sapiens_hsa043501.46525579
30Cell cycle_Homo sapiens_hsa041101.40413788
31Selenocompound metabolism_Homo sapiens_hsa004501.40373500
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.36471441
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32019676
34Sphingolipid metabolism_Homo sapiens_hsa006001.25751856
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.25456608
36Arachidonic acid metabolism_Homo sapiens_hsa005901.24461209
37Fatty acid metabolism_Homo sapiens_hsa012121.17171227
38Folate biosynthesis_Homo sapiens_hsa007901.16330137
39Peroxisome_Homo sapiens_hsa041461.15008865
40Olfactory transduction_Homo sapiens_hsa047401.11077218
41Purine metabolism_Homo sapiens_hsa002301.08853150
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08012624
43PI3K-Akt signaling pathway_Homo sapiens_hsa041511.06870783
44Homologous recombination_Homo sapiens_hsa034401.02198227
45Mismatch repair_Homo sapiens_hsa034301.00056609
46Focal adhesion_Homo sapiens_hsa045100.99563244
47Fanconi anemia pathway_Homo sapiens_hsa034600.98415372
48Thyroid cancer_Homo sapiens_hsa052160.97589529
49Hippo signaling pathway_Homo sapiens_hsa043900.97501491
50Galactose metabolism_Homo sapiens_hsa000520.94746381
51Prostate cancer_Homo sapiens_hsa052150.92430210
52Phagosome_Homo sapiens_hsa041450.92120527
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.91767873
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.90801423
55Pyrimidine metabolism_Homo sapiens_hsa002400.90107559
56Fatty acid degradation_Homo sapiens_hsa000710.88285572
57Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.86852673
58RNA transport_Homo sapiens_hsa030130.86115265
59Glutathione metabolism_Homo sapiens_hsa004800.85537308
60Insulin secretion_Homo sapiens_hsa049110.84075649
61Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.82222759
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81676345
63Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80135073
64Wnt signaling pathway_Homo sapiens_hsa043100.79253283
65Amphetamine addiction_Homo sapiens_hsa050310.78208767
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.78081868
67Basal cell carcinoma_Homo sapiens_hsa052170.77515444
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.76927042
69Glycosaminoglycan degradation_Homo sapiens_hsa005310.76621537
70Complement and coagulation cascades_Homo sapiens_hsa046100.76225298
71Proteoglycans in cancer_Homo sapiens_hsa052050.75623275
72Hedgehog signaling pathway_Homo sapiens_hsa043400.74538082
73Type I diabetes mellitus_Homo sapiens_hsa049400.74464948
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73851236
75Other glycan degradation_Homo sapiens_hsa005110.72591992
76Nitrogen metabolism_Homo sapiens_hsa009100.71280261
77Cocaine addiction_Homo sapiens_hsa050300.70944460
78mRNA surveillance pathway_Homo sapiens_hsa030150.70861859
79Melanoma_Homo sapiens_hsa052180.70255503
80Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70176096
81Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68543545
82Pyruvate metabolism_Homo sapiens_hsa006200.67097297
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65654304
84Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.64305393
85Serotonergic synapse_Homo sapiens_hsa047260.62862287
86Thyroid hormone synthesis_Homo sapiens_hsa049180.62627194
87Mineral absorption_Homo sapiens_hsa049780.62580439
88Steroid biosynthesis_Homo sapiens_hsa001000.62341742
89beta-Alanine metabolism_Homo sapiens_hsa004100.61617918
90Tryptophan metabolism_Homo sapiens_hsa003800.61342852
91Spliceosome_Homo sapiens_hsa030400.60916061
92Tight junction_Homo sapiens_hsa045300.59875124
93Phototransduction_Homo sapiens_hsa047440.59730358
94Malaria_Homo sapiens_hsa051440.59527061
95Retinol metabolism_Homo sapiens_hsa008300.59504694
96Collecting duct acid secretion_Homo sapiens_hsa049660.58721734
97Caffeine metabolism_Homo sapiens_hsa002320.58702824
98Legionellosis_Homo sapiens_hsa051340.58600251
99Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58244196
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.57368304
101Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57147082
102Circadian entrainment_Homo sapiens_hsa047130.56465058
103Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55032134
104Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.54873729
105Rheumatoid arthritis_Homo sapiens_hsa053230.54650703
106Renin secretion_Homo sapiens_hsa049240.53431402
107Adherens junction_Homo sapiens_hsa045200.52501898
108Circadian rhythm_Homo sapiens_hsa047100.51010717
109Metabolic pathways_Homo sapiens_hsa011000.50765485
110Regulation of autophagy_Homo sapiens_hsa041400.50286299
111Chemical carcinogenesis_Homo sapiens_hsa052040.49824977
112Taste transduction_Homo sapiens_hsa047420.49465491
113Dopaminergic synapse_Homo sapiens_hsa047280.49242820
114Melanogenesis_Homo sapiens_hsa049160.48565207
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48097393
116Glucagon signaling pathway_Homo sapiens_hsa049220.47810975
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47642233
118Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.47331094
119DNA replication_Homo sapiens_hsa030300.47312577
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.47147221
121HTLV-I infection_Homo sapiens_hsa051660.46641661
122Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.45990497
123Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45285751
124Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43754748
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.43382020
126One carbon pool by folate_Homo sapiens_hsa006700.42986521
127Epstein-Barr virus infection_Homo sapiens_hsa051690.42528757
128Huntingtons disease_Homo sapiens_hsa050160.42466672
129MicroRNAs in cancer_Homo sapiens_hsa052060.42357364
130Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.40664098
131Dilated cardiomyopathy_Homo sapiens_hsa054140.39544210
132p53 signaling pathway_Homo sapiens_hsa041150.38696851
133Renin-angiotensin system_Homo sapiens_hsa046140.38529570
134Carbon metabolism_Homo sapiens_hsa012000.38351850
135Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38272973
136Ether lipid metabolism_Homo sapiens_hsa005650.38235496
137Arginine and proline metabolism_Homo sapiens_hsa003300.37738655
138Oxidative phosphorylation_Homo sapiens_hsa001900.37576204
139Long-term depression_Homo sapiens_hsa047300.37269106
140Cysteine and methionine metabolism_Homo sapiens_hsa002700.37006742
141Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36891259
142Endometrial cancer_Homo sapiens_hsa052130.36871855
143Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35934200
144Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34945060
145Pathways in cancer_Homo sapiens_hsa052000.31684211
146Morphine addiction_Homo sapiens_hsa050320.31317849
147Alcoholism_Homo sapiens_hsa050340.31223180
148Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.30302778
149Parkinsons disease_Homo sapiens_hsa050120.30203145
150cGMP-PKG signaling pathway_Homo sapiens_hsa040220.29958474

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