TMEM266

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)7.50035148
2cerebellar granule cell differentiation (GO:0021707)5.35126937
3G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.87312518
4vocalization behavior (GO:0071625)4.85686448
5ionotropic glutamate receptor signaling pathway (GO:0035235)4.60941590
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.56480653
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.45104308
8glutamate receptor signaling pathway (GO:0007215)4.43522163
9synaptic transmission, glutamatergic (GO:0035249)4.43499545
10regulation of synapse maturation (GO:0090128)4.32225297
11cerebellar Purkinje cell differentiation (GO:0021702)4.28412643
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.28326698
13neurotransmitter-gated ion channel clustering (GO:0072578)4.27773469
14neuronal action potential propagation (GO:0019227)4.20101475
15locomotory exploration behavior (GO:0035641)4.06271322
16synaptic vesicle endocytosis (GO:0048488)4.06201007
17positive regulation of synapse maturation (GO:0090129)4.02981871
18L-fucose catabolic process (GO:0042355)4.02926798
19fucose catabolic process (GO:0019317)4.02926798
20L-fucose metabolic process (GO:0042354)4.02926798
21negative regulation of telomere maintenance (GO:0032205)3.98661201
22DNA deamination (GO:0045006)3.98293722
23synaptic vesicle docking involved in exocytosis (GO:0016081)3.95158243
24neuron-neuron synaptic transmission (GO:0007270)3.91347733
25negative regulation of synaptic transmission, GABAergic (GO:0032229)3.89896445
26regulation of synaptic vesicle exocytosis (GO:2000300)3.86410202
27regulation of glutamate receptor signaling pathway (GO:1900449)3.84169359
28regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.84158702
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.80893309
30regulation of synaptic vesicle transport (GO:1902803)3.79980354
31positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.77843285
32neurotransmitter secretion (GO:0007269)3.75774897
33kynurenine metabolic process (GO:0070189)3.73834695
34membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.73116199
35postsynaptic membrane organization (GO:0001941)3.72876053
36gamma-aminobutyric acid signaling pathway (GO:0007214)3.70831768
37detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.69725462
38gamma-aminobutyric acid transport (GO:0015812)3.66725884
39cell differentiation in hindbrain (GO:0021533)3.62759927
40neuron cell-cell adhesion (GO:0007158)3.62686781
41synaptic vesicle exocytosis (GO:0016079)3.59691025
42indole-containing compound catabolic process (GO:0042436)3.58900199
43indolalkylamine catabolic process (GO:0046218)3.58900199
44tryptophan catabolic process (GO:0006569)3.58900199
45protein localization to synapse (GO:0035418)3.51711363
46platelet dense granule organization (GO:0060155)3.49532923
47glutamate secretion (GO:0014047)3.48562374
48indolalkylamine metabolic process (GO:0006586)3.47686585
49water-soluble vitamin biosynthetic process (GO:0042364)3.42257637
50cellular potassium ion homeostasis (GO:0030007)3.38190654
51long-term memory (GO:0007616)3.30409599
52detection of light stimulus involved in sensory perception (GO:0050962)3.29821700
53detection of light stimulus involved in visual perception (GO:0050908)3.29821700
54synaptic vesicle maturation (GO:0016188)3.29379607
55regulation of neurotransmitter secretion (GO:0046928)3.28776238
56positive regulation of cellular amide metabolic process (GO:0034250)3.26297872
57presynaptic membrane organization (GO:0097090)3.21324560
58neuronal action potential (GO:0019228)3.20060535
59regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.20041895
60protein-cofactor linkage (GO:0018065)3.17678403
61sulfation (GO:0051923)3.17300984
62presynaptic membrane assembly (GO:0097105)3.14775093
63cellular anion homeostasis (GO:0030002)3.14429273
64mechanosensory behavior (GO:0007638)3.14101752
65exploration behavior (GO:0035640)3.13483779
66auditory behavior (GO:0031223)3.13197479
67mitochondrial respiratory chain complex I assembly (GO:0032981)3.12975258
68NADH dehydrogenase complex assembly (GO:0010257)3.12975258
69mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.12975258
70daunorubicin metabolic process (GO:0044597)3.12373639
71polyketide metabolic process (GO:0030638)3.12373639
72doxorubicin metabolic process (GO:0044598)3.12373639
73tryptophan metabolic process (GO:0006568)3.12358023
74epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.12303495
75righting reflex (GO:0060013)3.11537912
76regulation of excitatory postsynaptic membrane potential (GO:0060079)3.09585862
77glycine transport (GO:0015816)3.09314328
78protein complex biogenesis (GO:0070271)3.09048793
79cornea development in camera-type eye (GO:0061303)3.08136163
80regulation of nuclear cell cycle DNA replication (GO:0033262)3.05520784
81neurotransmitter transport (GO:0006836)3.05410237
82response to auditory stimulus (GO:0010996)3.04344292
83glycerophospholipid catabolic process (GO:0046475)3.02540947
84regulation of action potential (GO:0098900)2.99736330
85synaptic transmission, cholinergic (GO:0007271)2.98456882
86membrane depolarization during action potential (GO:0086010)2.96446525
87piRNA metabolic process (GO:0034587)2.95715812
88protein import into peroxisome matrix (GO:0016558)2.95616025
89regulation of synaptic transmission, glutamatergic (GO:0051966)2.95354938
90regulation of neurotransmitter transport (GO:0051588)2.93978326
91primary amino compound metabolic process (GO:1901160)2.93418084
92cellular ketone body metabolic process (GO:0046950)2.91456790
93startle response (GO:0001964)2.90173161
94positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.89058416
95behavioral response to ethanol (GO:0048149)2.88993818
96positive regulation of synapse assembly (GO:0051965)2.88008805
97regulation of postsynaptic membrane potential (GO:0060078)2.87324619
98nonmotile primary cilium assembly (GO:0035058)2.86659369
99indole-containing compound metabolic process (GO:0042430)2.86524324
100kidney morphogenesis (GO:0060993)2.84072616
101positive regulation of membrane potential (GO:0045838)2.83864751
102adult walking behavior (GO:0007628)2.83179021
103negative regulation of mast cell activation (GO:0033004)2.82943405
104behavioral response to nicotine (GO:0035095)2.82899487
105preassembly of GPI anchor in ER membrane (GO:0016254)2.82878269
106protein polyglutamylation (GO:0018095)2.81431956
107mitochondrial respiratory chain complex assembly (GO:0033108)2.80828701
108mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.76711649
109neural tube formation (GO:0001841)2.76342029
110regulation of cell communication by electrical coupling (GO:0010649)2.75769994
111long-term synaptic potentiation (GO:0060291)2.75635432
112membrane depolarization (GO:0051899)2.75610611
113neuromuscular synaptic transmission (GO:0007274)2.75326869
114positive regulation of neurotransmitter secretion (GO:0001956)2.75302603
115superoxide anion generation (GO:0042554)2.74248474
116neuromuscular process controlling posture (GO:0050884)2.73863337
117respiratory chain complex IV assembly (GO:0008535)2.73712739
118regulation of voltage-gated calcium channel activity (GO:1901385)2.72842039
119synapse assembly (GO:0007416)2.71438270
120epithelial cilium movement (GO:0003351)2.70854909
121regulation of neurotransmitter levels (GO:0001505)2.70471204
122auditory receptor cell stereocilium organization (GO:0060088)2.69954201
123regulation of long-term neuronal synaptic plasticity (GO:0048169)2.69312448
124membrane hyperpolarization (GO:0060081)2.68910172
125dopamine transport (GO:0015872)2.68301324
126positive regulation of fatty acid transport (GO:2000193)2.68149090
127ubiquinone biosynthetic process (GO:0006744)2.66449419
128nephron tubule morphogenesis (GO:0072078)2.66006196
129nephron epithelium morphogenesis (GO:0072088)2.66006196
130axoneme assembly (GO:0035082)2.65705591
131cAMP catabolic process (GO:0006198)2.63589243
132ketone body metabolic process (GO:1902224)2.63571585
133central nervous system projection neuron axonogenesis (GO:0021952)2.63222639
134maturation of 5.8S rRNA (GO:0000460)2.62991464
135negative regulation of hormone metabolic process (GO:0032351)2.62383180
136negative regulation of hormone biosynthetic process (GO:0032353)2.62383180
137reflex (GO:0060004)2.62329128
138parturition (GO:0007567)2.61618440
139regulation of synaptic transmission, GABAergic (GO:0032228)2.61540466
140regulation of synapse assembly (GO:0051963)2.61004894
141cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.60295962
142serotonin metabolic process (GO:0042428)2.60165497
143positive regulation of potassium ion transmembrane transport (GO:1901381)2.59375097
144long term synaptic depression (GO:0060292)2.59311709
145adaptation of signaling pathway (GO:0023058)2.59058511
146cellular response to ATP (GO:0071318)2.58819560
147regulation of telomere maintenance (GO:0032204)2.57277436
148behavioral response to pain (GO:0048266)2.56323570
149transmission of nerve impulse (GO:0019226)2.56244889
150learning (GO:0007612)2.55682462
151mannosylation (GO:0097502)2.55550195
152regulation of rhodopsin mediated signaling pathway (GO:0022400)2.55506388
153photoreceptor cell development (GO:0042461)2.55319834
154synaptic transmission (GO:0007268)2.55070550
155pyrimidine nucleobase catabolic process (GO:0006208)2.54699478
156ATP synthesis coupled proton transport (GO:0015986)2.53591441
157energy coupled proton transport, down electrochemical gradient (GO:0015985)2.53591441
158amine catabolic process (GO:0009310)2.52865838
159cellular biogenic amine catabolic process (GO:0042402)2.52865838
160rRNA catabolic process (GO:0016075)2.52844687
161cerebral cortex radially oriented cell migration (GO:0021799)2.50288026
162ubiquinone metabolic process (GO:0006743)2.49556576
163rhodopsin mediated signaling pathway (GO:0016056)2.49147559
164retinal cone cell development (GO:0046549)2.49070829
165glycosphingolipid biosynthetic process (GO:0006688)2.49032879
166negative regulation of cytosolic calcium ion concentration (GO:0051481)2.48787439
167detection of calcium ion (GO:0005513)2.48768301
168regulation of vesicle fusion (GO:0031338)2.46932920
169regulation of respiratory system process (GO:0044065)2.46283735
170synaptic vesicle transport (GO:0048489)2.46092804
171establishment of synaptic vesicle localization (GO:0097480)2.46092804
172proline transport (GO:0015824)2.45736369
173C4-dicarboxylate transport (GO:0015740)2.43721477
174DNA methylation involved in gamete generation (GO:0043046)2.43216291
175positive regulation of sodium ion transmembrane transport (GO:1902307)2.42937305
176action potential (GO:0001508)2.42544420
177multicellular organism reproduction (GO:0032504)2.42178201
178protein localization to cilium (GO:0061512)2.41914674
179negative regulation of reactive oxygen species metabolic process (GO:2000378)2.40978758
180cilium morphogenesis (GO:0060271)2.40823460
181somite development (GO:0061053)2.40539819
182dendritic spine morphogenesis (GO:0060997)2.40444545
183inner ear receptor stereocilium organization (GO:0060122)2.40325824
184cytochrome complex assembly (GO:0017004)2.39012858
185positive regulation of defense response to virus by host (GO:0002230)2.37468461
186positive regulation of prostaglandin secretion (GO:0032308)2.37157374

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.41778498
2GBX2_23144817_ChIP-Seq_PC3_Human4.37786212
3ZNF274_21170338_ChIP-Seq_K562_Hela4.15941692
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.57387009
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.53512248
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.46308066
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.42529299
8REST_21632747_ChIP-Seq_MESCs_Mouse2.35610928
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.33778062
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.32315627
11SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.24122455
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.22381243
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.20943327
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.18618100
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.18618100
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.17202265
17DROSHA_22980978_ChIP-Seq_HELA_Human2.14907891
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14086441
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.12055167
20JARID2_20075857_ChIP-Seq_MESCs_Mouse2.10236641
21EZH2_27294783_Chip-Seq_ESCs_Mouse1.95670142
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.95282120
23SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.93907789
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.89557490
25MTF2_20144788_ChIP-Seq_MESCs_Mouse1.89529598
26IKZF1_21737484_ChIP-ChIP_HCT116_Human1.85364059
27TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.85280118
28SMAD4_21799915_ChIP-Seq_A2780_Human1.84492260
29EWS_26573619_Chip-Seq_HEK293_Human1.82985024
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.82911398
31FUS_26573619_Chip-Seq_HEK293_Human1.82266147
32RNF2_27304074_Chip-Seq_ESCs_Mouse1.80068799
33SMAD_19615063_ChIP-ChIP_OVARY_Human1.78234072
34EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.76585528
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.75052656
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73184614
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.72132530
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.71577791
39SUZ12_27294783_Chip-Seq_ESCs_Mouse1.70451531
40FLI1_27457419_Chip-Seq_LIVER_Mouse1.69059041
41SUZ12_27294783_Chip-Seq_NPCs_Mouse1.68229624
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.64836527
43P300_19829295_ChIP-Seq_ESCs_Human1.64768136
44BCAT_22108803_ChIP-Seq_LS180_Human1.62874287
45NANOG_18555785_Chip-Seq_ESCs_Mouse1.61221122
46TP53_22573176_ChIP-Seq_HFKS_Human1.59899795
47IGF1R_20145208_ChIP-Seq_DFB_Human1.59258775
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58909408
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57456495
50IRF1_19129219_ChIP-ChIP_H3396_Human1.54761020
51TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.54135544
52E2F1_18555785_Chip-Seq_ESCs_Mouse1.52935138
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.52721807
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.52146149
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.51637534
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.51147419
57NFE2_27457419_Chip-Seq_LIVER_Mouse1.47497094
58RNF2_27304074_Chip-Seq_NSC_Mouse1.47129348
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.45634898
60P53_22387025_ChIP-Seq_ESCs_Mouse1.45049942
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44142427
62CBP_20019798_ChIP-Seq_JUKART_Human1.44142427
63STAT3_23295773_ChIP-Seq_U87_Human1.42632054
64STAT3_18555785_Chip-Seq_ESCs_Mouse1.40538334
65ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.40444888
66EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.40139509
67AR_21572438_ChIP-Seq_LNCaP_Human1.39984759
68RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39279462
69CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38789723
70SUZ12_18555785_Chip-Seq_ESCs_Mouse1.38118395
71SALL1_21062744_ChIP-ChIP_HESCs_Human1.37894046
72RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.35972613
73PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.35239193
74PIAS1_25552417_ChIP-Seq_VCAP_Human1.35203629
75CMYC_18555785_Chip-Seq_ESCs_Mouse1.34720121
76PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34281700
77ETV2_25802403_ChIP-Seq_MESCs_Mouse1.33665154
78GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.33352835
79NR3C1_21868756_ChIP-Seq_MCF10A_Human1.32835545
80NMYC_18555785_Chip-Seq_ESCs_Mouse1.32347082
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.31978883
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31978883
83GATA3_21878914_ChIP-Seq_MCF-7_Human1.31283779
84TCF4_23295773_ChIP-Seq_U87_Human1.30828523
85MYC_18940864_ChIP-ChIP_HL60_Human1.30693052
86FOXA1_27270436_Chip-Seq_PROSTATE_Human1.30116348
87FOXA1_25329375_ChIP-Seq_VCAP_Human1.30116348
88ER_23166858_ChIP-Seq_MCF-7_Human1.30072444
89AR_25329375_ChIP-Seq_VCAP_Human1.29546964
90SOX2_19829295_ChIP-Seq_ESCs_Human1.29305160
91NANOG_19829295_ChIP-Seq_ESCs_Human1.29305160
92EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.28715844
93SOX2_18555785_Chip-Seq_ESCs_Mouse1.28488082
94TAF15_26573619_Chip-Seq_HEK293_Human1.28436014
95VDR_22108803_ChIP-Seq_LS180_Human1.27258884
96CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.26760416
97EZH2_27294783_Chip-Seq_NPCs_Mouse1.26033589
98EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.23895329
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23235368
100P300_18555785_Chip-Seq_ESCs_Mouse1.22746224
101RUNX1_27457419_Chip-Seq_LIVER_Mouse1.22040298
102NCOR_22424771_ChIP-Seq_293T_Human1.21220828
103CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20892835
104SMAD3_21741376_ChIP-Seq_EPCs_Human1.19787932
105PU1_27457419_Chip-Seq_LIVER_Mouse1.19560369
106RUNX2_22187159_ChIP-Seq_PCA_Human1.18226905
107SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.17553571
108RARB_27405468_Chip-Seq_BRAIN_Mouse1.16581687
109TCF4_22108803_ChIP-Seq_LS180_Human1.15520950
110CTCF_18555785_Chip-Seq_ESCs_Mouse1.15344452
111AR_19668381_ChIP-Seq_PC3_Human1.15013196
112FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.14163692
113AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.14056397
114RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.13316562
115OCT4_18555785_Chip-Seq_ESCs_Mouse1.13016678
116TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13014964
117BP1_19119308_ChIP-ChIP_Hs578T_Human1.12094867
118ESRRB_18555785_Chip-Seq_ESCs_Mouse1.11896767
119KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11736211
120NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.11111344
121SOX2_21211035_ChIP-Seq_LN229_Gbm1.09530636
122ZFX_18555785_Chip-Seq_ESCs_Mouse1.08880883
123AR_20517297_ChIP-Seq_VCAP_Human1.08521136
124ARNT_22903824_ChIP-Seq_MCF-7_Human1.08384530
125MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06961095
126P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06545092
127KLF4_18555785_Chip-Seq_ESCs_Mouse1.06541720
128OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06054421
129FLI1_21867929_ChIP-Seq_TH2_Mouse1.05584191
130SMAD1_18555785_Chip-Seq_ESCs_Mouse1.05514607
131SMAD4_21741376_ChIP-Seq_EPCs_Human1.05056448
132ERA_21632823_ChIP-Seq_H3396_Human1.04746856
133TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04417207
134GABP_17652178_ChIP-ChIP_JURKAT_Human1.04209253
135MYC_19829295_ChIP-Seq_ESCs_Human1.03857837
136HOXB7_26014856_ChIP-Seq_BT474_Human1.03726222
137YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03107800
138PRDM14_20953172_ChIP-Seq_ESCs_Human1.02143730
139AUTS2_25519132_ChIP-Seq_293T-REX_Human1.01751302
140MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.01407273
141EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01353688
142FOXA1_21572438_ChIP-Seq_LNCaP_Human1.01065513
143TAF2_19829295_ChIP-Seq_ESCs_Human0.99611229
144NANOG_20526341_ChIP-Seq_ESCs_Human0.99514947
145CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.98761046

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.38768834
2MP0009046_muscle_twitch3.89323663
3MP0001188_hyperpigmentation3.32906603
4MP0003635_abnormal_synaptic_transmissio3.19377726
5MP0003880_abnormal_central_pattern3.13769412
6MP0009745_abnormal_behavioral_response2.87705158
7MP0006292_abnormal_olfactory_placode2.74725914
8MP0001968_abnormal_touch/_nociception2.65729114
9MP0002735_abnormal_chemical_nociception2.65352327
10MP0002063_abnormal_learning/memory/cond2.61918052
11MP0002064_seizures2.53871367
12MP0002572_abnormal_emotion/affect_behav2.50274301
13MP0002736_abnormal_nociception_after2.48600244
14MP0005646_abnormal_pituitary_gland2.48555211
15MP0005423_abnormal_somatic_nervous2.41341860
16MP0003787_abnormal_imprinting2.37132852
17MP0002638_abnormal_pupillary_reflex2.32029419
18MP0002734_abnormal_mechanical_nocicepti2.27693345
19MP0002837_dystrophic_cardiac_calcinosis2.27418356
20MP0002067_abnormal_sensory_capabilities2.26396035
21MP0002272_abnormal_nervous_system2.26242309
22MP0008569_lethality_at_weaning2.25197322
23MP0001486_abnormal_startle_reflex2.19521628
24MP0003195_calcinosis2.17365942
25MP0005645_abnormal_hypothalamus_physiol2.10169517
26MP0002653_abnormal_ependyma_morphology2.07294908
27MP0001501_abnormal_sleep_pattern2.07283051
28MP0002184_abnormal_innervation2.01207995
29MP0003646_muscle_fatigue1.99756155
30MP0002557_abnormal_social/conspecific_i1.91135850
31MP0001502_abnormal_circadian_rhythm1.90821087
32MP0008872_abnormal_physiological_respon1.90302239
33MP0000566_synostosis1.88889472
34MP0001440_abnormal_grooming_behavior1.87107163
35MP0005551_abnormal_eye_electrophysiolog1.85569896
36MP0008875_abnormal_xenobiotic_pharmacok1.83909336
37MP0006276_abnormal_autonomic_nervous1.83265754
38MP0004270_analgesia1.82533989
39MP0010386_abnormal_urinary_bladder1.79906987
40MP0001984_abnormal_olfaction1.77175688
41MP0004742_abnormal_vestibular_system1.76260744
42MP0000372_irregular_coat_pigmentation1.72682712
43MP0004133_heterotaxia1.71519509
44MP0005386_behavior/neurological_phenoty1.70921266
45MP0004924_abnormal_behavior1.70921266
46MP0004043_abnormal_pH_regulation1.69451472
47MP0004142_abnormal_muscle_tone1.66776155
48MP0002733_abnormal_thermal_nociception1.64957358
49MP0001970_abnormal_pain_threshold1.62507100
50MP0003879_abnormal_hair_cell1.60552628
51MP0009697_abnormal_copulation1.59745850
52MP0000569_abnormal_digit_pigmentation1.52637317
53MP0002876_abnormal_thyroid_physiology1.49225636
54MP0004782_abnormal_surfactant_physiolog1.47463105
55MP0000778_abnormal_nervous_system1.42861768
56MP0003011_delayed_dark_adaptation1.42194468
57MP0000015_abnormal_ear_pigmentation1.40871689
58MP0004147_increased_porphyrin_level1.38091728
59MP0005084_abnormal_gallbladder_morpholo1.36130768
60MP0005253_abnormal_eye_physiology1.30629336
61MP0004145_abnormal_muscle_electrophysio1.30207382
62MP0008260_abnormal_autophagy1.25782101
63MP0003283_abnormal_digestive_organ1.25549617
64MP0000427_abnormal_hair_cycle1.25076626
65MP0004811_abnormal_neuron_physiology1.22022319
66MP0005171_absent_coat_pigmentation1.21197784
67MP0002066_abnormal_motor_capabilities/c1.20956094
68MP0000678_abnormal_parathyroid_gland1.20646822
69MP0005167_abnormal_blood-brain_barrier1.16913635
70MP0002882_abnormal_neuron_morphology1.16901312
71MP0002254_reproductive_system_inflammat1.13753988
72MP0001986_abnormal_taste_sensitivity1.12833855
73MP0002277_abnormal_respiratory_mucosa1.12516501
74MP0005174_abnormal_tail_pigmentation1.11947267
75MP0001905_abnormal_dopamine_level1.11604617
76MP0000955_abnormal_spinal_cord1.09320857
77MP0005195_abnormal_posterior_eye1.08406728
78MP0003183_abnormal_peptide_metabolism1.04506555
79MP0006072_abnormal_retinal_apoptosis1.03738848
80MP0001963_abnormal_hearing_physiology1.01186698
81MP0005389_reproductive_system_phenotype0.97887484
82MP0002928_abnormal_bile_duct0.97558679
83MP0002102_abnormal_ear_morphology0.95706735
84MP0008004_abnormal_stomach_pH0.92537058
85MP0002160_abnormal_reproductive_system0.92226332
86MP0003718_maternal_effect0.91865434
87MP0000230_abnormal_systemic_arterial0.90353296
88MP0005377_hearing/vestibular/ear_phenot0.89300887
89MP0003878_abnormal_ear_physiology0.89300887
90MP0002234_abnormal_pharynx_morphology0.88850388
91MP0005499_abnormal_olfactory_system0.88513196
92MP0005394_taste/olfaction_phenotype0.88513196
93MP0004484_altered_response_of0.88362656
94MP0002229_neurodegeneration0.87437911
95MP0005410_abnormal_fertilization0.87010587
96MP0000681_abnormal_thyroid_gland0.84332682
97MP0004885_abnormal_endolymph0.84254633
98MP0003137_abnormal_impulse_conducting0.82074299
99MP0004215_abnormal_myocardial_fiber0.81706273
100MP0002163_abnormal_gland_morphology0.80073581
101MP0002752_abnormal_somatic_nervous0.79670537
102MP0008775_abnormal_heart_ventricle0.79644210
103MP0003121_genomic_imprinting0.79304880
104MP0002152_abnormal_brain_morphology0.78536525
105MP0000026_abnormal_inner_ear0.78007023
106MP0001177_atelectasis0.77225978
107MP0004130_abnormal_muscle_cell0.77114951
108MP0003941_abnormal_skin_development0.76169403
109MP0008789_abnormal_olfactory_epithelium0.75769889
110MP0001529_abnormal_vocalization0.75127442
111MP0003633_abnormal_nervous_system0.73963894
112MP0003632_abnormal_nervous_system0.72952900
113MP0001324_abnormal_eye_pigmentation0.72521985
114MP0002069_abnormal_eating/drinking_beha0.72461969
115MP0005448_abnormal_energy_balance0.72460710
116MP0004858_abnormal_nervous_system0.72367395
117MP0003631_nervous_system_phenotype0.71925710
118MP0002693_abnormal_pancreas_physiology0.71823379
119MP0001485_abnormal_pinna_reflex0.71803633
120MP0005535_abnormal_body_temperature0.70456112
121MP0000383_abnormal_hair_follicle0.69341636
122MP0005409_darkened_coat_color0.68401337
123MP0003122_maternal_imprinting0.66576662
124MP0008877_abnormal_DNA_methylation0.66052994
125MP0004510_myositis0.63200707
126MP0002148_abnormal_hypersensitivity_rea0.62991766
127MP0005379_endocrine/exocrine_gland_phen0.61856295
128MP0001919_abnormal_reproductive_system0.61780123
129MP0008995_early_reproductive_senescence0.60270208
130MP0000631_abnormal_neuroendocrine_gland0.58840670
131MP0002909_abnormal_adrenal_gland0.57429785
132MP0002095_abnormal_skin_pigmentation0.57136114
133MP0003172_abnormal_lysosome_physiology0.56515710
134MP0002938_white_spotting0.55692468
135MP0003136_yellow_coat_color0.54679805

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.67909863
2Febrile seizures (HP:0002373)5.55442026
3Progressive cerebellar ataxia (HP:0002073)4.96820962
4Epileptic encephalopathy (HP:0200134)4.78886976
5Abnormality of midbrain morphology (HP:0002418)4.18694194
6Molar tooth sign on MRI (HP:0002419)4.18694194
7Gaze-evoked nystagmus (HP:0000640)3.86507144
8Nephronophthisis (HP:0000090)3.80810869
9Focal seizures (HP:0007359)3.68903441
10Visual hallucinations (HP:0002367)3.50696124
11Atonic seizures (HP:0010819)3.49503779
12Type II lissencephaly (HP:0007260)3.43336442
13Hyperventilation (HP:0002883)3.36472631
14Abnormal drinking behavior (HP:0030082)3.35098404
15Polydipsia (HP:0001959)3.35098404
16Action tremor (HP:0002345)3.30408976
17Broad-based gait (HP:0002136)3.29650035
18Abnormality of the renal medulla (HP:0100957)3.25199717
19Congenital stationary night blindness (HP:0007642)3.16811179
20Abnormality of the renal cortex (HP:0011035)3.10381155
21Abnormal hair whorl (HP:0010721)3.00255273
22Absent rod-and cone-mediated responses on ERG (HP:0007688)2.86955787
23Tubular atrophy (HP:0000092)2.84863164
24Protruding tongue (HP:0010808)2.84576046
25Attenuation of retinal blood vessels (HP:0007843)2.83429383
26Absent eyebrow (HP:0002223)2.78449756
27Fetal akinesia sequence (HP:0001989)2.76687952
28Chronic hepatic failure (HP:0100626)2.76641604
29Cystic liver disease (HP:0006706)2.72346193
30Poor eye contact (HP:0000817)2.68752891
31Abnormality of alanine metabolism (HP:0010916)2.67769847
32Hyperalaninemia (HP:0003348)2.67769847
33Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.67769847
34Impaired smooth pursuit (HP:0007772)2.67201908
35Absence seizures (HP:0002121)2.66237115
36Generalized tonic-clonic seizures (HP:0002069)2.65565619
37Abnormal rod and cone electroretinograms (HP:0008323)2.60105492
38Polyuria (HP:0000103)2.57970408
39Decreased circulating renin level (HP:0003351)2.54041699
40Myokymia (HP:0002411)2.52141351
41Dialeptic seizures (HP:0011146)2.50065342
42Decreased central vision (HP:0007663)2.49939956
43Sclerocornea (HP:0000647)2.47437669
44Genetic anticipation (HP:0003743)2.45000827
45Optic nerve hypoplasia (HP:0000609)2.44077279
46Aplasia/Hypoplasia of the fovea (HP:0008060)2.43788004
47Hypoplasia of the fovea (HP:0007750)2.43788004
48Acute necrotizing encephalopathy (HP:0006965)2.41214207
49Chromosomal breakage induced by crosslinking agents (HP:0003221)2.41088772
50Congenital, generalized hypertrichosis (HP:0004540)2.37934818
51Mitochondrial inheritance (HP:0001427)2.36000214
52Septo-optic dysplasia (HP:0100842)2.34950875
53Abnormality of ocular smooth pursuit (HP:0000617)2.34933664
54Spinal canal stenosis (HP:0003416)2.32998662
55Increased CSF lactate (HP:0002490)2.31528332
56Absent speech (HP:0001344)2.30313683
57Choroideremia (HP:0001139)2.29189135
58Hemiparesis (HP:0001269)2.28614092
59Lissencephaly (HP:0001339)2.27317505
60Scanning speech (HP:0002168)2.27022318
61Oligodactyly (hands) (HP:0001180)2.26995953
62Fair hair (HP:0002286)2.26775955
63Dysdiadochokinesis (HP:0002075)2.24751860
64Abnormal social behavior (HP:0012433)2.22197022
65Impaired social interactions (HP:0000735)2.22197022
66Dysmetric saccades (HP:0000641)2.21254119
67Limb dystonia (HP:0002451)2.20166779
68Acute encephalopathy (HP:0006846)2.19395499
69Generalized hypopigmentation of hair (HP:0011358)2.18570490
70Nephrogenic diabetes insipidus (HP:0009806)2.17895715
71Cerebellar dysplasia (HP:0007033)2.17079193
72Progressive macrocephaly (HP:0004481)2.14059208
73Increased corneal curvature (HP:0100692)2.12215170
74Keratoconus (HP:0000563)2.12215170
75Decreased electroretinogram (ERG) amplitude (HP:0000654)2.12210719
76Concave nail (HP:0001598)2.11590702
77Inability to walk (HP:0002540)2.10430489
78Blue irides (HP:0000635)2.10099268
79Lipid accumulation in hepatocytes (HP:0006561)2.09174747
80Progressive inability to walk (HP:0002505)2.08381217
81Large for gestational age (HP:0001520)2.08140857
82Congenital hepatic fibrosis (HP:0002612)2.07872726
83Central scotoma (HP:0000603)2.07743304
84Furrowed tongue (HP:0000221)2.07605573
85Horizontal nystagmus (HP:0000666)2.07449379
86Gait imbalance (HP:0002141)2.07119966
87Anencephaly (HP:0002323)2.06741244
88Bile duct proliferation (HP:0001408)2.06225627
89Abnormal biliary tract physiology (HP:0012439)2.06225627
90Abnormal urine output (HP:0012590)2.06133536
91Excessive salivation (HP:0003781)2.03928225
92Drooling (HP:0002307)2.03928225
93Congenital sensorineural hearing impairment (HP:0008527)2.03774318
94Hepatocellular necrosis (HP:0001404)2.03635043
95Esotropia (HP:0000565)2.03500633
96Abnormal mitochondria in muscle tissue (HP:0008316)2.02938973
97Optic disc pallor (HP:0000543)2.02455867
98Type 2 muscle fiber atrophy (HP:0003554)2.02020288
99Aplasia/Hypoplasia of the tongue (HP:0010295)2.01989579
100Abnormality of the pons (HP:0007361)2.01630982
101Hypoplasia of the pons (HP:0012110)2.01546508
102Dyschromatopsia (HP:0007641)2.01440476
103Abnormality of the fovea (HP:0000493)1.99663800
104Abnormality of binocular vision (HP:0011514)1.98104811
105Diplopia (HP:0000651)1.98104811
106True hermaphroditism (HP:0010459)1.97716393
107Severe muscular hypotonia (HP:0006829)1.96707821
108Truncal ataxia (HP:0002078)1.96019292
1093-Methylglutaconic aciduria (HP:0003535)1.95412110
110Stomach cancer (HP:0012126)1.95274854
111Methylmalonic acidemia (HP:0002912)1.95158529
112Male pseudohermaphroditism (HP:0000037)1.94182654
113Status epilepticus (HP:0002133)1.93473831
114Patellar aplasia (HP:0006443)1.93264197
115Unilateral renal agenesis (HP:0000122)1.93055043
116Absent/shortened dynein arms (HP:0200106)1.91894211
117Dynein arm defect of respiratory motile cilia (HP:0012255)1.91894211
118Clumsiness (HP:0002312)1.90894942
119Aplasia/Hypoplasia of the spleen (HP:0010451)1.90153718
120Bony spicule pigmentary retinopathy (HP:0007737)1.89957683
121Hyperphosphatemia (HP:0002905)1.89127765
122Aplasia/Hypoplasia of the patella (HP:0006498)1.88959473
123Abnormal EKG (HP:0003115)1.88358096
124Hepatic necrosis (HP:0002605)1.87936170
125Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.86919594
126Medial flaring of the eyebrow (HP:0010747)1.86330398
127Pheochromocytoma (HP:0002666)1.84737607
128Abnormal eating behavior (HP:0100738)1.84326401
129Methylmalonic aciduria (HP:0012120)1.84282752
130Abnormality of the labia minora (HP:0012880)1.82906988
131Retrobulbar optic neuritis (HP:0100654)1.82756203
132Optic neuritis (HP:0100653)1.82756203
133Hyperglycinuria (HP:0003108)1.82100273
134Chromsome breakage (HP:0040012)1.81774449
135Split foot (HP:0001839)1.81454943
136Congenital primary aphakia (HP:0007707)1.81048048
137Abnormality of macular pigmentation (HP:0008002)1.79705990
138Hip dysplasia (HP:0001385)1.79149046
139Rib fusion (HP:0000902)1.78995291
140Chorioretinal atrophy (HP:0000533)1.78308601
141Optic nerve coloboma (HP:0000588)1.77289524
142Pachygyria (HP:0001302)1.77050888
143Pendular nystagmus (HP:0012043)1.76369336
144Genital tract atresia (HP:0001827)1.76140557
145Abnormality of renal excretion (HP:0011036)1.75987095
146Nonprogressive disorder (HP:0003680)1.75811545
147Neonatal hypoglycemia (HP:0001998)1.74777530
148Aplasia/Hypoplasia of the tibia (HP:0005772)1.73118082
149Asplenia (HP:0001746)1.73065433
150Epileptiform EEG discharges (HP:0011182)1.72791440
151Polyphagia (HP:0002591)1.72742301
152Abolished electroretinogram (ERG) (HP:0000550)1.72640042
153Pancreatic fibrosis (HP:0100732)1.70955899
154Failure to thrive in infancy (HP:0001531)1.70953178
155Retinal dysplasia (HP:0007973)1.70543730
156Stereotypic behavior (HP:0000733)1.69270601
157Dysmetria (HP:0001310)1.68672608
158Severe visual impairment (HP:0001141)1.68411479
159Photophobia (HP:0000613)1.66858568
160Renal cortical cysts (HP:0000803)1.64519727
161Ventricular fibrillation (HP:0001663)1.63131581
162Poor coordination (HP:0002370)1.63035612
163Pancreatic cysts (HP:0001737)1.62436615
164Cutaneous finger syndactyly (HP:0010554)1.60986286
165Labial hypoplasia (HP:0000066)1.60239083
166Constricted visual fields (HP:0001133)1.59847148
167Abnormality of the lower motor neuron (HP:0002366)1.59769884

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.75937459
2CASK4.29795715
3SIK33.58585362
4NTRK33.58212197
5PRPF4B2.99920479
6TLK12.88753949
7MAP4K22.82274499
8WNK42.71078492
9MARK12.69215468
10MAP2K72.64388338
11AKT32.42005888
12SGK22.36998862
13TAOK32.24839442
14TAOK22.20213079
15CAMKK22.17929129
16DAPK22.17388975
17PINK11.90956212
18ERBB31.88259671
19MAPK131.86888427
20OXSR11.82800409
21PLK21.82355957
22SGK4941.78000866
23SGK2231.78000866
24TNIK1.77688038
25ACVR1B1.75149275
26MAP3K141.73298376
27TXK1.70267765
28NTRK21.63082760
29MAP3K41.62046921
30SGK31.60422104
31INSRR1.55970454
32ZAK1.46461176
33RIPK41.41965195
34MAP3K121.41888797
35CAMKK11.34791671
36STK391.34283527
37BMPR21.30965500
38CCNB11.29268038
39SIK21.25825838
40PRKCG1.25557294
41STK381.24758883
42WNK11.23163627
43PAK31.22391997
44IRAK31.19522727
45ADRBK11.19044095
46EPHA41.19031841
47NEK61.16664235
48OBSCN1.14648710
49DAPK11.12666591
50MINK11.10197057
51MAPK151.09223924
52TRIM281.08195527
53CDK31.06406803
54ADRBK21.05237762
55BMPR1B1.05211514
56NME11.03521868
57WNK30.98728711
58TNK20.92164472
59VRK10.91432094
60GRK50.91190359
61TIE10.90406702
62PTK2B0.89286455
63GRK10.88726790
64TGFBR10.88419087
65MAPKAPK30.87369438
66MAPKAPK50.86855685
67NUAK10.86564216
68MKNK20.86416888
69MUSK0.85127611
70DYRK1A0.84413058
71PRKCQ0.83428628
72YES10.83054319
73SGK10.81927423
74BCKDK0.81091829
75CDK80.79944416
76PIK3CA0.77425962
77PHKG20.77190441
78PHKG10.77190441
79CAMK2A0.74885782
80BRD40.74158931
81CAMK10.73928071
82STK38L0.73910557
83CDK190.73727442
84PNCK0.73660416
85CAMK40.72849400
86CDK50.72024249
87PRKCE0.70717710
88EIF2AK20.70614493
89STK240.70570287
90CSNK1G20.70356145
91TSSK60.69551059
92IRAK20.69338558
93MAP2K40.67444579
94IRAK40.66278116
95FGFR20.63041099
96CSNK1G30.61550840
97KSR10.61360729
98VRK20.61339587
99RPS6KA50.59971257
100PAK60.59077213
101IKBKB0.57351169
102STK30.57173414
103BRAF0.56465608
104PRKCI0.55725797
105CSNK1G10.53931314
106PRKCZ0.51906358
107RIPK10.51823106
108MAPK70.50314452
109CDC42BPA0.50168575
110BCR0.49764347
111CAMK2G0.48876355
112RPS6KB10.48258411
113STK160.47395973
114KIT0.47001522
115PKN10.46153809
116PRKAA10.45689976
117PRKG10.44174483
118ITK0.43591533
119TEC0.43504485
120PASK0.43209624
121MARK30.42130828
122MAP2K20.41224907
123CSNK1A1L0.40827379
124PRKACA0.39665371
125MAP2K60.39198818
126PRKAA20.39169078
127LATS10.38999414
128LMTK20.38932854
129PRKCA0.38354449
130CAMK2B0.37995403
131GRK70.37798647
132PLK40.37449553
133PLK30.37246462
134DYRK20.36431786
135PRKCH0.36393693
136SRPK10.36274390
137EPHA20.36163423
138STK110.35091499
139CSNK1D0.33748494
140CDK180.31692685
141CHUK0.31418961
142CSNK1A10.31159037
143IKBKE0.30895881
144JAK10.30873181
145RPS6KA60.30808723
146CHEK20.30731993

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.97842650
2Synaptic vesicle cycle_Homo sapiens_hsa047213.52220644
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.93922374
4Morphine addiction_Homo sapiens_hsa050322.78151846
5Oxidative phosphorylation_Homo sapiens_hsa001902.75368460
6Linoleic acid metabolism_Homo sapiens_hsa005912.69109009
7Glutamatergic synapse_Homo sapiens_hsa047242.67452593
8Taste transduction_Homo sapiens_hsa047422.64141840
9Circadian entrainment_Homo sapiens_hsa047132.57151010
10Phototransduction_Homo sapiens_hsa047442.57015506
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.54615440
12GABAergic synapse_Homo sapiens_hsa047272.52066411
13Nitrogen metabolism_Homo sapiens_hsa009102.42244584
14Olfactory transduction_Homo sapiens_hsa047402.25517440
15Parkinsons disease_Homo sapiens_hsa050122.20762876
16Long-term potentiation_Homo sapiens_hsa047202.05742090
17Maturity onset diabetes of the young_Homo sapiens_hsa049502.05079382
18Butanoate metabolism_Homo sapiens_hsa006502.02090620
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.00116965
20Insulin secretion_Homo sapiens_hsa049111.86318677
21Long-term depression_Homo sapiens_hsa047301.86077864
22Salivary secretion_Homo sapiens_hsa049701.80841879
23Collecting duct acid secretion_Homo sapiens_hsa049661.79656786
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.77498057
25Amphetamine addiction_Homo sapiens_hsa050311.75207871
26Ether lipid metabolism_Homo sapiens_hsa005651.74527798
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.74515736
28Selenocompound metabolism_Homo sapiens_hsa004501.69941531
29Tryptophan metabolism_Homo sapiens_hsa003801.62367978
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.60443239
31Calcium signaling pathway_Homo sapiens_hsa040201.60251813
32Cholinergic synapse_Homo sapiens_hsa047251.54737994
33Alzheimers disease_Homo sapiens_hsa050101.54244629
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.54124813
35Serotonergic synapse_Homo sapiens_hsa047261.52588055
36Basal transcription factors_Homo sapiens_hsa030221.47755968
37Aldosterone synthesis and secretion_Homo sapiens_hsa049251.47620288
38Type II diabetes mellitus_Homo sapiens_hsa049301.45902456
39Homologous recombination_Homo sapiens_hsa034401.45222606
40Dopaminergic synapse_Homo sapiens_hsa047281.45077742
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.41697923
42RNA polymerase_Homo sapiens_hsa030201.39669055
43Protein export_Homo sapiens_hsa030601.37943976
44Huntingtons disease_Homo sapiens_hsa050161.37560361
45Type I diabetes mellitus_Homo sapiens_hsa049401.36101012
46Rheumatoid arthritis_Homo sapiens_hsa053231.35878669
47Caffeine metabolism_Homo sapiens_hsa002321.32241689
48SNARE interactions in vesicular transport_Homo sapiens_hsa041301.30271903
49Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.29605821
50Intestinal immune network for IgA production_Homo sapiens_hsa046721.27342061
51Circadian rhythm_Homo sapiens_hsa047101.23113339
52Oxytocin signaling pathway_Homo sapiens_hsa049211.17796214
53Arachidonic acid metabolism_Homo sapiens_hsa005901.13800851
54Peroxisome_Homo sapiens_hsa041461.11519476
55RNA degradation_Homo sapiens_hsa030181.09403058
56cAMP signaling pathway_Homo sapiens_hsa040241.09204984
57Chemical carcinogenesis_Homo sapiens_hsa052041.08872969
58Gastric acid secretion_Homo sapiens_hsa049711.08050263
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.06293795
60Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.05543521
61ABC transporters_Homo sapiens_hsa020101.03407715
62Propanoate metabolism_Homo sapiens_hsa006401.01977708
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01755515
64Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.01390109
65Steroid hormone biosynthesis_Homo sapiens_hsa001401.00952141
66Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.99718137
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.99065176
68Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.97832979
69Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.95820021
70Inositol phosphate metabolism_Homo sapiens_hsa005620.94087332
71Regulation of autophagy_Homo sapiens_hsa041400.93802570
72Toll-like receptor signaling pathway_Homo sapiens_hsa046200.93313604
73Renin secretion_Homo sapiens_hsa049240.91175948
74Retinol metabolism_Homo sapiens_hsa008300.90030949
75Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.89947620
76Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.89737032
77Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88566684
78Cocaine addiction_Homo sapiens_hsa050300.87891647
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87644214
80Primary bile acid biosynthesis_Homo sapiens_hsa001200.86210506
81One carbon pool by folate_Homo sapiens_hsa006700.86064565
82Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.83905517
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80634443
84Sulfur relay system_Homo sapiens_hsa041220.80618243
85Fructose and mannose metabolism_Homo sapiens_hsa000510.80209826
86Ribosome_Homo sapiens_hsa030100.79935791
87GnRH signaling pathway_Homo sapiens_hsa049120.78456348
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75051713
89Vibrio cholerae infection_Homo sapiens_hsa051100.74338111
90Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.73579530
91Asthma_Homo sapiens_hsa053100.73473877
92cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73186409
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72388885
94Autoimmune thyroid disease_Homo sapiens_hsa053200.70917916
95Phagosome_Homo sapiens_hsa041450.70463645
96Graft-versus-host disease_Homo sapiens_hsa053320.69481727
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69184888
98Axon guidance_Homo sapiens_hsa043600.67644659
99Mineral absorption_Homo sapiens_hsa049780.67147309
100Fat digestion and absorption_Homo sapiens_hsa049750.66943169
101Glycerolipid metabolism_Homo sapiens_hsa005610.66629314
102Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66096057
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65449448
104Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.64868135
105Tuberculosis_Homo sapiens_hsa051520.63344611
106Purine metabolism_Homo sapiens_hsa002300.62009706
107Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59301350
108Metabolic pathways_Homo sapiens_hsa011000.58054690
109Pancreatic secretion_Homo sapiens_hsa049720.57020421
110African trypanosomiasis_Homo sapiens_hsa051430.56706724
111beta-Alanine metabolism_Homo sapiens_hsa004100.56380504
112ErbB signaling pathway_Homo sapiens_hsa040120.56205534
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.55800795
114Histidine metabolism_Homo sapiens_hsa003400.55308356
115Allograft rejection_Homo sapiens_hsa053300.54922475
116Primary immunodeficiency_Homo sapiens_hsa053400.54177658
117Dilated cardiomyopathy_Homo sapiens_hsa054140.51981776
118Ovarian steroidogenesis_Homo sapiens_hsa049130.51514124
119MAPK signaling pathway_Homo sapiens_hsa040100.51118188
120Vitamin digestion and absorption_Homo sapiens_hsa049770.50399993
121Chemokine signaling pathway_Homo sapiens_hsa040620.48725859
122Estrogen signaling pathway_Homo sapiens_hsa049150.48601907
123Sphingolipid metabolism_Homo sapiens_hsa006000.48484884
124Gap junction_Homo sapiens_hsa045400.48101348
125Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.47788138
126Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47652388
127Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47602742
128RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.47229696
129Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.46124212
130Vascular smooth muscle contraction_Homo sapiens_hsa042700.44012604
131Melanogenesis_Homo sapiens_hsa049160.42328494
132Dorso-ventral axis formation_Homo sapiens_hsa043200.41569035
133Cardiac muscle contraction_Homo sapiens_hsa042600.41544148
134TNF signaling pathway_Homo sapiens_hsa046680.40808735
135Influenza A_Homo sapiens_hsa051640.39993757
136Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.39375384
137Fatty acid degradation_Homo sapiens_hsa000710.39121768
138Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38814016
139Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38634259
140Sulfur metabolism_Homo sapiens_hsa009200.36000026
141Cysteine and methionine metabolism_Homo sapiens_hsa002700.35895732
142Salmonella infection_Homo sapiens_hsa051320.35550069
143Phospholipase D signaling pathway_Homo sapiens_hsa040720.35379957
144Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35024914
145Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33325403
146Thyroid hormone synthesis_Homo sapiens_hsa049180.33191681
147Choline metabolism in cancer_Homo sapiens_hsa052310.32248053
148NF-kappa B signaling pathway_Homo sapiens_hsa040640.31769869
149Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.31516411
150Arginine and proline metabolism_Homo sapiens_hsa003300.30736700
151Endometrial cancer_Homo sapiens_hsa052130.28174035
152Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.27631777
153FoxO signaling pathway_Homo sapiens_hsa040680.27483861
154Fanconi anemia pathway_Homo sapiens_hsa034600.27063479
155Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.26927029
156Glycerophospholipid metabolism_Homo sapiens_hsa005640.26779279
157Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26393837

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