TMEM30B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1desmosome organization (GO:0002934)6.43085243
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.09430517
3L-phenylalanine catabolic process (GO:0006559)6.09430517
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.91366627
5L-phenylalanine metabolic process (GO:0006558)5.91366627
6aromatic amino acid family catabolic process (GO:0009074)5.35354181
7sulfur amino acid catabolic process (GO:0000098)5.31052419
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.28196043
9intestinal epithelial cell development (GO:0060576)5.10893164
10intestinal cholesterol absorption (GO:0030299)5.06713999
11cysteine metabolic process (GO:0006534)4.97818099
12high-density lipoprotein particle remodeling (GO:0034375)4.80456229
13urea metabolic process (GO:0019627)4.78073643
14urea cycle (GO:0000050)4.78073643
15metanephric mesenchyme development (GO:0072075)4.75909344
16tryptophan catabolic process (GO:0006569)4.75863559
17indole-containing compound catabolic process (GO:0042436)4.75863559
18indolalkylamine catabolic process (GO:0046218)4.75863559
19kynurenine metabolic process (GO:0070189)4.67897231
20homocysteine metabolic process (GO:0050667)4.64231009
21bile acid biosynthetic process (GO:0006699)4.59731314
22tryptophan metabolic process (GO:0006568)4.57555636
23calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.51613731
24glyoxylate metabolic process (GO:0046487)4.49366065
25alpha-linolenic acid metabolic process (GO:0036109)4.39608685
26intestinal absorption (GO:0050892)4.39328679
27regulation of triglyceride catabolic process (GO:0010896)4.39227136
28nitrogen cycle metabolic process (GO:0071941)4.34467854
29regulation of water loss via skin (GO:0033561)4.33444695
30reverse cholesterol transport (GO:0043691)4.32398059
31peptidyl-glutamic acid carboxylation (GO:0017187)4.32223357
32protein carboxylation (GO:0018214)4.32223357
33diterpenoid biosynthetic process (GO:0016102)4.32012989
34multicellular organismal water homeostasis (GO:0050891)4.31800937
35bile acid and bile salt transport (GO:0015721)4.26059852
36bile acid metabolic process (GO:0008206)4.23246266
37phospholipid efflux (GO:0033700)4.22055833
38amino-acid betaine metabolic process (GO:0006577)4.17654166
39lysine catabolic process (GO:0006554)4.17001798
40lysine metabolic process (GO:0006553)4.17001798
41serine family amino acid catabolic process (GO:0009071)4.16552611
42regulation of cholesterol esterification (GO:0010872)4.15641229
43negative regulation of fibrinolysis (GO:0051918)4.14281944
44negative regulation of sterol transport (GO:0032372)4.13951986
45negative regulation of cholesterol transport (GO:0032375)4.13951986
46cellular glucuronidation (GO:0052695)4.10115103
47regulation of transforming growth factor beta2 production (GO:0032909)4.07925368
48kidney mesenchyme development (GO:0072074)4.06631301
49drug catabolic process (GO:0042737)4.03623285
50fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.03503608
51regulation of fibrinolysis (GO:0051917)4.03494466
52plasma lipoprotein particle remodeling (GO:0034369)4.03410532
53protein-lipid complex remodeling (GO:0034368)4.03410532
54macromolecular complex remodeling (GO:0034367)4.03410532
55triglyceride homeostasis (GO:0070328)4.01911367
56acylglycerol homeostasis (GO:0055090)4.01911367
57complement activation, alternative pathway (GO:0006957)4.01119394
58regulation of protein activation cascade (GO:2000257)3.99739331
59aromatic amino acid family metabolic process (GO:0009072)3.94472905
60flavonoid metabolic process (GO:0009812)3.90161914
61regulation of cholesterol homeostasis (GO:2000188)3.89219207
62transcytosis (GO:0045056)3.86643340
63regulation of bile acid biosynthetic process (GO:0070857)3.78447708
64ethanol oxidation (GO:0006069)3.78135631
65cholesterol efflux (GO:0033344)3.77544111
66regulation of complement activation (GO:0030449)3.73352634
67uronic acid metabolic process (GO:0006063)3.73072981
68glucuronate metabolic process (GO:0019585)3.73072981
69cellular modified amino acid catabolic process (GO:0042219)3.71786984
70establishment of skin barrier (GO:0061436)3.70679100
71negative regulation of kidney development (GO:0090185)3.70011058
72water homeostasis (GO:0030104)3.69459915
73alpha-amino acid catabolic process (GO:1901606)3.68757522
74plasma lipoprotein particle assembly (GO:0034377)3.67330254
75cellular ketone body metabolic process (GO:0046950)3.65464677
76drug transmembrane transport (GO:0006855)3.64994660
77tyrosine metabolic process (GO:0006570)3.61820623
78regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.60603598
79nephron tubule formation (GO:0072079)3.59783869
80cellular amino acid catabolic process (GO:0009063)3.54926858
81bundle of His cell to Purkinje myocyte communication (GO:0086069)3.52891546
82benzene-containing compound metabolic process (GO:0042537)3.52889586
83myoblast migration (GO:0051451)3.52346510
84negative regulation of lipase activity (GO:0060192)3.51448822
85cholesterol homeostasis (GO:0042632)3.50405645
86glandular epithelial cell differentiation (GO:0002067)3.50280415
87hemidesmosome assembly (GO:0031581)3.50187767
88regulation of cardioblast differentiation (GO:0051890)3.49395160
89positive regulation of triglyceride lipase activity (GO:0061365)3.48769513
90positive regulation of lipoprotein lipase activity (GO:0051006)3.48769513
91regulation of type B pancreatic cell apoptotic process (GO:2000674)3.47392509
92sterol homeostasis (GO:0055092)3.46486318
93lipoprotein metabolic process (GO:0042157)3.45616382
94indolalkylamine metabolic process (GO:0006586)3.45424088
95plasma lipoprotein particle clearance (GO:0034381)3.43206937
96very-low-density lipoprotein particle assembly (GO:0034379)3.42403624
97phospholipid homeostasis (GO:0055091)3.41657508
98chemical homeostasis within a tissue (GO:0048875)3.40936893
99thyroid hormone generation (GO:0006590)3.40753695
100columnar/cuboidal epithelial cell development (GO:0002066)3.40363166
101surfactant homeostasis (GO:0043129)3.39949162
102drug metabolic process (GO:0017144)3.39860923
103ethanol metabolic process (GO:0006067)3.38419280
104serine family amino acid metabolic process (GO:0009069)3.37293194
105response to nitrosative stress (GO:0051409)3.36976678
106glutamate metabolic process (GO:0006536)3.36031044
107positive regulation of lipid catabolic process (GO:0050996)3.35745445
108short-chain fatty acid metabolic process (GO:0046459)3.35640638
109epoxygenase P450 pathway (GO:0019373)3.34064135
110regulation of cholesterol biosynthetic process (GO:0045540)3.33014951
111glycine metabolic process (GO:0006544)3.32113723
112xenobiotic catabolic process (GO:0042178)3.31762962
113nodal signaling pathway (GO:0038092)3.30708795
114coenzyme catabolic process (GO:0009109)3.29186897
115protein-lipid complex assembly (GO:0065005)3.28283862
116exogenous drug catabolic process (GO:0042738)3.28121212
117vitamin transmembrane transport (GO:0035461)3.24914145
118fibrinolysis (GO:0042730)3.24337564
119carnitine metabolic process (GO:0009437)3.23280761
120carboxylic acid catabolic process (GO:0046395)3.22903753
121organic acid catabolic process (GO:0016054)3.22903753
122renal filtration (GO:0097205)3.20645547
123tight junction assembly (GO:0070830)3.20425576
124primary alcohol catabolic process (GO:0034310)3.20192174
125fatty acid oxidation (GO:0019395)3.19976768
126imidazole-containing compound metabolic process (GO:0052803)3.18224595
127segment specification (GO:0007379)3.18104801
128regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.17322151
129fatty acid beta-oxidation (GO:0006635)3.16868667
130glomerular filtration (GO:0003094)3.16511156
131thyroid hormone metabolic process (GO:0042403)3.13818618
132auditory receptor cell differentiation (GO:0042491)3.11582374
133peptide catabolic process (GO:0043171)3.11228829
134planar cell polarity pathway involved in neural tube closure (GO:0090179)3.05572900
135Golgi transport vesicle coating (GO:0048200)3.00724069
136COPI coating of Golgi vesicle (GO:0048205)3.00724069
137retinol metabolic process (GO:0042572)3.00655985
138amino-acid betaine transport (GO:0015838)2.92327490
139carnitine transport (GO:0015879)2.92327490
140face development (GO:0060324)2.91014606
141regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.89587612
142O-glycan processing (GO:0016266)2.86122225
143phenylpropanoid metabolic process (GO:0009698)2.83723194
144negative regulation of hormone metabolic process (GO:0032351)2.82175841
145negative regulation of keratinocyte proliferation (GO:0010839)2.81902143
146endocrine pancreas development (GO:0031018)2.81048156
147generation of neurons (GO:0048699)2.80671235
148terpenoid biosynthetic process (GO:0016114)2.79863451
149sphingomyelin metabolic process (GO:0006684)2.78930216
150regulation of keratinocyte differentiation (GO:0045616)2.77877614
151primary alcohol metabolic process (GO:0034308)2.75424541
152maternal placenta development (GO:0001893)2.72484916
153COPII vesicle coating (GO:0048208)2.72308405
154pyrimidine-containing compound transmembrane transport (GO:0072531)2.72224064
155ear development (GO:0043583)2.71076511
156regulation of transforming growth factor beta production (GO:0071634)2.68824120
157phosphate ion transmembrane transport (GO:0035435)2.68619278
158regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.68148857
159gap junction assembly (GO:0016264)2.67315293
160axonemal dynein complex assembly (GO:0070286)2.64695930
161regulation of cardioblast proliferation (GO:0003264)2.62176340
162regulation of secondary heart field cardioblast proliferation (GO:0003266)2.62176340
163positive regulation of epidermal cell differentiation (GO:0045606)2.61178238
164epithelial cell maturation (GO:0002070)2.61145275
165branching involved in mammary gland duct morphogenesis (GO:0060444)2.59924909
166digestion (GO:0007586)2.59903069
167negative regulation of catenin import into nucleus (GO:0035414)2.59473866
168regulation of heart rate by cardiac conduction (GO:0086091)2.59225394
169artery smooth muscle contraction (GO:0014824)2.58509866
170negative regulation of hormone biosynthetic process (GO:0032353)2.57952374
171embryonic eye morphogenesis (GO:0048048)2.55153963
172muscle cell migration (GO:0014812)2.54858143
173regulation of transforming growth factor beta1 production (GO:0032908)2.54106277
174neuron fate specification (GO:0048665)2.53934031
175regulation of keratinocyte proliferation (GO:0010837)2.53691191
176negative regulation of complement activation (GO:0045916)2.53620509
177regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.53366108
178angiotensin maturation (GO:0002003)2.52508299
179quaternary ammonium group transport (GO:0015697)2.51055507
180steroid hormone mediated signaling pathway (GO:0043401)2.50527871
181carnitine transmembrane transport (GO:1902603)2.49714547
182transepithelial transport (GO:0070633)2.49234312
183sperm capacitation (GO:0048240)2.48200039
184thyroid gland development (GO:0030878)2.48198959
185negative regulation of cell fate commitment (GO:0010454)2.47279423
186ER overload response (GO:0006983)2.45898616
187mesenchyme morphogenesis (GO:0072132)2.45547689
188retinoic acid metabolic process (GO:0042573)2.44280971
189Leydig cell differentiation (GO:0033327)2.42775279

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse9.16396530
2RXR_22158963_ChIP-Seq_LIVER_Mouse6.65575657
3PPARA_22158963_ChIP-Seq_LIVER_Mouse5.93922421
4LXR_22158963_ChIP-Seq_LIVER_Mouse5.39853458
5TP63_17297297_ChIP-ChIP_HaCaT_Human5.15915569
6EGR1_23403033_ChIP-Seq_LIVER_Mouse5.13814610
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.10362360
8PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.77680665
9CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.76838177
10NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.33287618
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.85065921
12CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.67774292
13* SOX2_27498859_Chip-Seq_STOMACH_Mouse2.51431366
14HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.34950717
15ESR1_21235772_ChIP-Seq_MCF-7_Human2.22526814
16ZNF263_19887448_ChIP-Seq_K562_Human2.12579309
17CDX2_20551321_ChIP-Seq_CACO-2_Human2.10598465
18GATA4_25053715_ChIP-Seq_YYC3_Human2.09542954
19STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.06613157
20ESR2_21235772_ChIP-Seq_MCF-7_Human2.02213869
21CLOCK_20551151_ChIP-Seq_293T_Human1.78254015
22ARNT_22903824_ChIP-Seq_MCF-7_Human1.72244115
23TRIM28_21343339_ChIP-Seq_HEK293_Human1.71539677
24GATA6_25053715_ChIP-Seq_YYC3_Human1.69879968
25TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.67149284
26FOXA2_19822575_ChIP-Seq_HepG2_Human1.65788071
27* SOX2_20726797_ChIP-Seq_SW620_Human1.64103864
28HIF1A_21447827_ChIP-Seq_MCF-7_Human1.63743098
29GATA1_22025678_ChIP-Seq_K562_Human1.57125118
30TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55129990
31PIAS1_25552417_ChIP-Seq_VCAP_Human1.46560796
32ESR1_20079471_ChIP-ChIP_T-47D_Human1.43674722
33HNF4A_19822575_ChIP-Seq_HepG2_Human1.39150338
34FOXO3_23340844_ChIP-Seq_DLD1_Human1.35932615
35ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.35413097
36NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.34417744
37FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.31076366
38PPAR_26484153_Chip-Seq_NCI-H1993_Human1.30067130
39* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.25748159
40RARG_19884340_ChIP-ChIP_MEFs_Mouse1.24525690
41FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.23637431
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.19023866
43TCF4_18268006_ChIP-ChIP_LS174T_Human1.18608252
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.14896593
45ELF5_23300383_ChIP-Seq_T47D_Human1.13675637
46* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12598280
47FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.12200321
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11687368
49BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.10507318
50HTT_18923047_ChIP-ChIP_STHdh_Human1.09802815
51GATA3_24758297_ChIP-Seq_MCF-7_Human1.08131403
52CHD1_26751641_Chip-Seq_LNCaP_Human1.07640366
53ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.06173572
54KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.05934909
55KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.05934909
56KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.05934909
57P63_26484246_Chip-Seq_KERATINOCYTES_Human1.05244557
58SOX9_24532713_ChIP-Seq_HFSC_Mouse1.02507637
59SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.02091905
60CTNNB1_20460455_ChIP-Seq_HCT116_Human1.01364832
61RACK7_27058665_Chip-Seq_MCF-7_Human0.99778920
62SALL4_18804426_ChIP-ChIP_XEN_Mouse0.99637791
63FOXA1_25552417_ChIP-Seq_VCAP_Human0.99627185
64RUNX1_27514584_Chip-Seq_MCF-7_Human0.99030949
65PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.98147404
66KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.97701564
67ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.97583822
68BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97050070
69ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.94871804
70KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92630322
71TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90809756
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.90738453
73WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.88515768
74SMAD3_21741376_ChIP-Seq_HESCs_Human0.88366890
75PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.87949374
76FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.87643155
77TP63_22573176_ChIP-Seq_HFKS_Human0.86333448
78RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.84574270
79RXR_22108803_ChIP-Seq_LS180_Human0.82476332
80* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.81901158
81NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.81860275
82* EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.81516455
83PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.81339864
84RXRA_24833708_ChIP-Seq_LIVER_Mouse0.80495090
85TBX20_22080862_ChIP-Seq_HEART_Mouse0.79498225
86TBX20_22328084_ChIP-Seq_HEART_Mouse0.79498225
87* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.78937394
88RING1B_27294783_Chip-Seq_NPCs_Mouse0.78802885
89ATF3_27146783_Chip-Seq_COLON_Human0.77873088
90FOXM1_26456572_ChIP-Seq_MCF-7_Human0.76211470
91WT1_25993318_ChIP-Seq_PODOCYTE_Human0.75909753
92P300_27058665_Chip-Seq_ZR-75-30cells_Human0.75288732
93* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.73801794
94SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.73682202
95EP300_21415370_ChIP-Seq_HL-1_Mouse0.72748712
96TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.72689072
97CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.71568246
98TP63_23658742_ChIP-Seq_EP156T_Human0.70457033
99CDX2_19796622_ChIP-Seq_MESCs_Mouse0.69836502
100CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.69403635
101IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.69048962
102PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.68682131
103SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.68105430
104SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.68105430
105EGR1_19032775_ChIP-ChIP_M12_Human0.67950900
106NRF2_20460467_ChIP-Seq_MEFs_Mouse0.67536399
107NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.67536399
108LXR_22292898_ChIP-Seq_THP-1_Human0.67076000
109AHR_22903824_ChIP-Seq_MCF-7_Human0.66787796
110CDX2_22108803_ChIP-Seq_LS180_Human0.65598525
111ESR1_15608294_ChIP-ChIP_MCF-7_Human0.65499483
112KLF5_25053715_ChIP-Seq_YYC3_Human0.65458868
113CEBPB_22108803_ChIP-Seq_LS180_Human0.65444801
114TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.65159916
115CREB1_26743006_Chip-Seq_LNCaP_Human0.65116360
116PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.64452637
117KAP1_22055183_ChIP-Seq_ESCs_Mouse0.62504886
118CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.61994400
119BCAT_22108803_ChIP-Seq_LS180_Human0.61445711
120RAD21_21589869_ChIP-Seq_MESCs_Mouse0.61152862
121Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.58355572
122THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.58036202
123STAT3_1855785_ChIP-Seq_MESCs_Mouse0.57668870
124GATA2_19941826_ChIP-Seq_K562_Human0.55747408
125RARA_24833708_ChIP-Seq_LIVER_Mouse0.55573742
126AR_21909140_ChIP-Seq_LNCAP_Human0.55137359
127CJUN_26792858_Chip-Seq_BT549_Human0.54688764
128AR_20517297_ChIP-Seq_VCAP_Human0.54278477
129ERG_20517297_ChIP-Seq_VCAP_Human0.54115414

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.68835946
2MP0005360_urolithiasis6.51970399
3MP0005085_abnormal_gallbladder_physiolo5.43520393
4MP0005365_abnormal_bile_salt5.22605802
5MP0008875_abnormal_xenobiotic_pharmacok4.43858426
6MP0001666_abnormal_nutrient_absorption3.72397734
7MP0003252_abnormal_bile_duct3.50397359
8MP0010234_abnormal_vibrissa_follicle3.42348322
9MP0003806_abnormal_nucleotide_metabolis3.18230638
10MP0010329_abnormal_lipoprotein_level2.91066924
11MP0005083_abnormal_biliary_tract2.67805770
12MP0003195_calcinosis2.62137693
13MP0009840_abnormal_foam_cell2.46404868
14MP0004019_abnormal_vitamin_homeostasis2.34454129
15MP0005332_abnormal_amino_acid2.27086145
16MP0004264_abnormal_extraembryonic_tissu2.20343009
17MP0003283_abnormal_digestive_organ2.11147082
18MP0002138_abnormal_hepatobiliary_system1.97072517
19MP0002254_reproductive_system_inflammat1.85780929
20MP0002796_impaired_skin_barrier1.82719002
21MP0003191_abnormal_cellular_cholesterol1.82123448
22MP0005409_darkened_coat_color1.81934222
23MP0002909_abnormal_adrenal_gland1.79583485
24MP0003868_abnormal_feces_composition1.77710780
25MP0000609_abnormal_liver_physiology1.74756662
26MP0002118_abnormal_lipid_homeostasis1.74573397
27MP0010030_abnormal_orbit_morphology1.67591605
28MP0009643_abnormal_urine_homeostasis1.67158087
29MP0003705_abnormal_hypodermis_morpholog1.55162969
30MP0005451_abnormal_body_composition1.54695051
31MP0008004_abnormal_stomach_pH1.44481975
32MP0005220_abnormal_exocrine_pancreas1.41789145
33MP0005319_abnormal_enzyme/_coenzyme1.40795528
34MP0000762_abnormal_tongue_morphology1.30643207
35MP0004043_abnormal_pH_regulation1.29076606
36MP0002896_abnormal_bone_mineralization1.28200250
37MP0002098_abnormal_vibrissa_morphology1.25030408
38MP0005636_abnormal_mineral_homeostasis1.22585328
39MP0005503_abnormal_tendon_morphology1.17229633
40MP0010678_abnormal_skin_adnexa1.15931688
41MP0001188_hyperpigmentation1.15745800
42MP0004133_heterotaxia1.15252505
43MP0002163_abnormal_gland_morphology1.13073414
44MP0001764_abnormal_homeostasis1.12165816
45MP0002132_abnormal_respiratory_system1.09344403
46MP0005379_endocrine/exocrine_gland_phen1.05742751
47MP0003566_abnormal_cell_adhesion1.05645924
48MP0001756_abnormal_urination1.05258023
49MP0002060_abnormal_skin_morphology1.04172308
50MP0003453_abnormal_keratinocyte_physiol1.03649053
51MP0000579_abnormal_nail_morphology1.03092537
52MP0005408_hypopigmentation1.02292113
53MP0002233_abnormal_nose_morphology1.02171805
54MP0003866_abnormal_defecation1.01773807
55MP0000470_abnormal_stomach_morphology1.00863733
56MP0000462_abnormal_digestive_system1.00568898
57MP0000566_synostosis0.99037399
58MP0005584_abnormal_enzyme/coenzyme_acti0.98954482
59MP0003300_gastrointestinal_ulcer0.98597725
60MP0001270_distended_abdomen0.98062112
61MP0002876_abnormal_thyroid_physiology0.94961506
62MP0008789_abnormal_olfactory_epithelium0.93653411
63MP0005647_abnormal_sex_gland0.91462069
64MP0001765_abnormal_ion_homeostasis0.91378212
65MP0000538_abnormal_urinary_bladder0.90986878
66MP0003186_abnormal_redox_activity0.90248013
67MP0004782_abnormal_surfactant_physiolog0.89866795
68MP0002168_other_aberrant_phenotype0.89308097
69MP0005501_abnormal_skin_physiology0.89129274
70MP0003115_abnormal_respiratory_system0.87713016
71MP0005248_abnormal_Harderian_gland0.86635278
72MP0000003_abnormal_adipose_tissue0.85652625
73MP0003011_delayed_dark_adaptation0.85257033
74MP0009053_abnormal_anal_canal0.84702643
75MP0000681_abnormal_thyroid_gland0.83808437
76MP0000598_abnormal_liver_morphology0.83413174
77MP0009379_abnormal_foot_pigmentation0.81977674
78MP0001216_abnormal_epidermal_layer0.81917894
79MP0000627_abnormal_mammary_gland0.81661417
80MP0001873_stomach_inflammation0.81451075
81MP0000013_abnormal_adipose_tissue0.81054010
82MP0005084_abnormal_gallbladder_morpholo0.79322468
83MP0009384_cardiac_valve_regurgitation0.79303432
84MP0001485_abnormal_pinna_reflex0.76828480
85MP0000467_abnormal_esophagus_morphology0.75711918
86MP0001664_abnormal_digestion0.74714174
87MP0001177_atelectasis0.74405726
88MP0009642_abnormal_blood_homeostasis0.74136798
89MP0002396_abnormal_hematopoietic_system0.74000950
90MP0004381_abnormal_hair_follicle0.73974971
91MP0000377_abnormal_hair_follicle0.73264918
92MP0002078_abnormal_glucose_homeostasis0.73211886
93MP0002932_abnormal_joint_morphology0.72903029
94MP0000537_abnormal_urethra_morphology0.71858106
95MP0000613_abnormal_salivary_gland0.71788182
96MP0002136_abnormal_kidney_physiology0.71130230
97MP0000534_abnormal_ureter_morphology0.70592328
98MP0002089_abnormal_postnatal_growth/wei0.70207258
99MP0009697_abnormal_copulation0.69910695
100MP0009931_abnormal_skin_appearance0.69728388
101MP0005275_abnormal_skin_tensile0.68545113
102MP0005023_abnormal_wound_healing0.67402738
103MP0001944_abnormal_pancreas_morphology0.67326495
104MP0009764_decreased_sensitivity_to0.66013719
105MP0002877_abnormal_melanocyte_morpholog0.65616382
106MP0000383_abnormal_hair_follicle0.64999334
107MP0005381_digestive/alimentary_phenotyp0.64864387
108MP0001849_ear_inflammation0.63061006
109MP0004947_skin_inflammation0.62951724
110MP0001663_abnormal_digestive_system0.62635660
111MP0001346_abnormal_lacrimal_gland0.62600084
112MP0009780_abnormal_chondrocyte_physiolo0.60010047
113MP0000427_abnormal_hair_cycle0.58403633
114MP0010155_abnormal_intestine_physiology0.57367683
115MP0008469_abnormal_protein_level0.57119624
116MP0000477_abnormal_intestine_morphology0.56509792
117MP0003941_abnormal_skin_development0.56222627
118MP0003638_abnormal_response/metabolism_0.55514555
119MP0009765_abnormal_xenobiotic_induced0.54640635
120MP0000604_amyloidosis0.54152605
121MP0009763_increased_sensitivity_to0.53999110
122MP0001881_abnormal_mammary_gland0.52726835
123MP0002277_abnormal_respiratory_mucosa0.52560738
124MP0003656_abnormal_erythrocyte_physiolo0.51783471
125MP0010386_abnormal_urinary_bladder0.51693190
126MP0010352_gastrointestinal_tract_polyps0.51420017
127MP0005187_abnormal_penis_morphology0.51151808
128MP0005448_abnormal_energy_balance0.50905466
129MP0003183_abnormal_peptide_metabolism0.50662087
130MP0000678_abnormal_parathyroid_gland0.49599082
131MP0010771_integument_phenotype0.49358863
132MP0002693_abnormal_pancreas_physiology0.48642777
133MP0003879_abnormal_hair_cell0.48111073
134MP0006054_spinal_hemorrhage0.47990243

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)6.56153956
2Abnormality of monocarboxylic acid metabolism (HP:0010996)6.06618220
3Abnormality of aromatic amino acid family metabolism (HP:0004338)6.03793454
4Deep venous thrombosis (HP:0002625)5.58473102
5Lip pit (HP:0100267)5.38295216
6Hypobetalipoproteinemia (HP:0003563)5.36464540
7Xanthomatosis (HP:0000991)5.22498286
8Prolonged partial thromboplastin time (HP:0003645)5.03873452
9Abnormality of glutamine family amino acid metabolism (HP:0010902)4.36817509
10Fat malabsorption (HP:0002630)4.35330221
11Conjugated hyperbilirubinemia (HP:0002908)4.30382762
12Hypoglycemic coma (HP:0001325)4.17804771
13Decreased circulating renin level (HP:0003351)4.04977086
14Hypolipoproteinemia (HP:0010981)4.02734105
15Hyperammonemia (HP:0001987)4.00843262
16Hyperglycinuria (HP:0003108)3.98612135
17Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.93374621
18Complement deficiency (HP:0004431)3.88983259
19Hyperlipoproteinemia (HP:0010980)3.88694401
20Pili torti (HP:0003777)3.86895861
21Abnormality of renin-angiotensin system (HP:0000847)3.80816745
22Right ventricular cardiomyopathy (HP:0011663)3.79726465
23Ketosis (HP:0001946)3.79232087
24Hyperglycinemia (HP:0002154)3.76378193
25Abnormality of the common coagulation pathway (HP:0010990)3.74478983
26Abnormality of sulfur amino acid metabolism (HP:0004339)3.70319045
27Epidermoid cyst (HP:0200040)3.66910932
28Abnormality of serine family amino acid metabolism (HP:0010894)3.56834323
29Abnormality of glycine metabolism (HP:0010895)3.56834323
30Abnormality of the intrinsic pathway (HP:0010989)3.56572078
31Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.55223485
32Abnormality of aspartate family amino acid metabolism (HP:0010899)3.51256401
33Malnutrition (HP:0004395)3.43084281
34Hypoalphalipoproteinemia (HP:0003233)3.41402988
35Hyperaldosteronism (HP:0000859)3.39314954
36Hyperphosphatemia (HP:0002905)3.38516071
37Joint hemorrhage (HP:0005261)3.37404675
38Ileus (HP:0002595)3.35283474
39Ketoacidosis (HP:0001993)3.30132333
40Rectal prolapse (HP:0002035)3.27064652
41Curly hair (HP:0002212)3.25173325
42Gout (HP:0001997)3.25083750
43Abnormality of purine metabolism (HP:0004352)3.11539969
44Abnormality of methionine metabolism (HP:0010901)3.08970052
45Hypoglycemic seizures (HP:0002173)3.05677092
46Abnormality of nucleobase metabolism (HP:0010932)3.05059344
47Chronic bronchitis (HP:0004469)3.04749637
48Steatorrhea (HP:0002570)3.04458131
49Abnormality of fatty-acid metabolism (HP:0004359)2.98674522
50Abnormality of pyrimidine metabolism (HP:0004353)2.92098095
51Abnormal hair laboratory examination (HP:0003328)2.91815193
52Abnormal biliary tract morphology (HP:0012440)2.89576003
53Metabolic alkalosis (HP:0200114)2.87203989
54Hepatocellular carcinoma (HP:0001402)2.86477161
55Late onset (HP:0003584)2.86422529
56Abnormality of complement system (HP:0005339)2.82268864
57Hypercholesterolemia (HP:0003124)2.82196381
58Abnormal pancreas size (HP:0012094)2.80995666
59Hyperbilirubinemia (HP:0002904)2.80078860
60Septate vagina (HP:0001153)2.72784998
61Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.70847086
62Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.68300515
63Vascular calcification (HP:0004934)2.66774485
64Abnormality of permanent molar morphology (HP:0011071)2.66261636
65Abnormality of the dental root (HP:0006486)2.66261636
66Taurodontia (HP:0000679)2.66261636
67Alopecia of scalp (HP:0002293)2.65990884
68Exocrine pancreatic insufficiency (HP:0001738)2.64536860
69Male infertility (HP:0003251)2.59448149
70Symptomatic seizures (HP:0011145)2.59380554
71Metabolic acidosis (HP:0001942)2.58551463
72Plantar hyperkeratosis (HP:0007556)2.57752211
73Hyperinsulinemic hypoglycemia (HP:0000825)2.52509395
74Abnormality of molar (HP:0011077)2.52204978
75Abnormality of molar morphology (HP:0011070)2.52204978
76Hyperactive renin-angiotensin system (HP:0000841)2.52069853
77Flat acetabular roof (HP:0003180)2.51293455
78Skin nodule (HP:0200036)2.50377368
79Increased circulating renin level (HP:0000848)2.50249058
80Abnormality of proline metabolism (HP:0010907)2.47185999
81Hydroxyprolinuria (HP:0003080)2.47185999
82Generalized aminoaciduria (HP:0002909)2.46840559
83Renal salt wasting (HP:0000127)2.46816651
84Acanthocytosis (HP:0001927)2.44826157
85Mitral stenosis (HP:0001718)2.44588506
86Alkalosis (HP:0001948)2.42670127
87Pancreatitis (HP:0001733)2.41741015
88Esophageal varix (HP:0002040)2.41391891
89Delayed CNS myelination (HP:0002188)2.39444296
90Hyperkalemia (HP:0002153)2.38827974
91Hyponatremia (HP:0002902)2.38720276
92Hypoplasia of dental enamel (HP:0006297)2.37569616
93Growth hormone excess (HP:0000845)2.36853066
94Hyperglycemia (HP:0003074)2.36513044
95Abnormality of calcium-phosphate metabolism (HP:0100530)2.36329242
96Biliary tract neoplasm (HP:0100574)2.35832319
97Cardiovascular calcification (HP:0011915)2.34499409
98Abnormality of the dental pulp (HP:0006479)2.33772526
99Abdominal distention (HP:0003270)2.33465034
100Bronchiectasis (HP:0002110)2.32914372
101Hyperparathyroidism (HP:0000843)2.32438572
102Rhinitis (HP:0012384)2.31069209
103Hypotension (HP:0002615)2.30621556
104Myocardial infarction (HP:0001658)2.29202465
105Dicarboxylic aciduria (HP:0003215)2.28317472
106Abnormality of dicarboxylic acid metabolism (HP:0010995)2.28317472
107Lethargy (HP:0001254)2.28023935
108Arterial tortuosity (HP:0005116)2.25833123
109Adrenal overactivity (HP:0002717)2.24170591
110Amelogenesis imperfecta (HP:0000705)2.23870319
111Proximal tubulopathy (HP:0000114)2.22565528
112Abnormality of nail color (HP:0100643)2.21489949
113Glycosuria (HP:0003076)2.20914074
114Abnormality of urine glucose concentration (HP:0011016)2.20914074
115Palmoplantar hyperkeratosis (HP:0000972)2.20893470
116Abnormality of potassium homeostasis (HP:0011042)2.20020443
117Abnormal respiratory motile cilium morphology (HP:0005938)2.19903413
118Abnormal respiratory epithelium morphology (HP:0012253)2.19903413
119Hypokalemia (HP:0002900)2.19380325
120Irritability (HP:0000737)2.19134677
121Goiter (HP:0000853)2.18648090
122Abnormality of serum amino acid levels (HP:0003112)2.18315780
123Widely patent fontanelles and sutures (HP:0004492)2.15128111
124Abnormal respiratory motile cilium physiology (HP:0012261)2.15081725
125Rickets (HP:0002748)2.14029513
126Hyperuricemia (HP:0002149)2.13852887
127Increased purine levels (HP:0004368)2.13852887
128Hypoplastic labia majora (HP:0000059)2.13570637
129Abnormality of the gastric mucosa (HP:0004295)2.13489617
130Spontaneous abortion (HP:0005268)2.12160576
131Abnormality of the distal phalanges of the toes (HP:0010182)2.11726763
132Flattened epiphyses (HP:0003071)2.10789812
133Abnormality of chloride homeostasis (HP:0011422)2.10507080
134Atrophic scars (HP:0001075)2.10122914
135Breast carcinoma (HP:0003002)2.06176628
136Insulin-resistant diabetes mellitus (HP:0000831)2.05744064
137Protuberant abdomen (HP:0001538)2.05533369
138Popliteal pterygium (HP:0009756)2.04858411
139Renal tubular acidosis (HP:0001947)2.03177995
140Abnormal ciliary motility (HP:0012262)2.02569054
141Spastic diplegia (HP:0001264)2.02498528
142Germ cell neoplasia (HP:0100728)2.02002527
143Abnormal cartilage morphology (HP:0002763)2.01786196
144Abnormality of vitamin metabolism (HP:0100508)2.01286579
145Atrioventricular block (HP:0001678)2.01212034
146Tongue fasciculations (HP:0001308)2.00574066
147Milia (HP:0001056)2.00547008
148Fragile nails (HP:0001808)1.99737629
149Palmar hyperkeratosis (HP:0010765)1.97774607
150Renal cortical cysts (HP:0000803)1.97562910
151Onycholysis (HP:0001806)1.96891873
152Abnormal enzyme/coenzyme activity (HP:0012379)1.94412234
153Abnormality of small intestinal villus morphology (HP:0011472)1.93811046
154Villous atrophy (HP:0011473)1.93811046
155Potter facies (HP:0002009)1.93591983
156Facial shape deformation (HP:0011334)1.93591983
157Abnormality of the nasal septum (HP:0000419)1.91791024
158Enlarged kidneys (HP:0000105)1.89450301
159Vomiting (HP:0002013)1.88232562
160Abnormality of vitamin B metabolism (HP:0004340)1.87319864
161Amyloidosis (HP:0011034)1.86839228
162Hypotrichosis (HP:0001006)1.86677618
163Abnormality of sodium homeostasis (HP:0010931)1.85854974
164Nausea (HP:0002018)1.85169054
165Nephrolithiasis (HP:0000787)1.83589298
166Abnormal hemoglobin (HP:0011902)1.82809507
167Abnormal gallbladder morphology (HP:0012437)1.82162017
168Abnormal tarsal ossification (HP:0008369)1.80351435
169Abnormality of alkaline phosphatase activity (HP:0004379)1.77211680
170Systemic lupus erythematosus (HP:0002725)1.76599428
171Menorrhagia (HP:0000132)1.76378240
172Dehydration (HP:0001944)1.76178245
173Glomerulonephritis (HP:0000099)1.75412702
174Hypophosphatemic rickets (HP:0004912)1.75388610
175Neonatal onset (HP:0003623)1.75274656
176Abnormality of transition element cation homeostasis (HP:0011030)1.72404131

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.31427056
2FRK4.07728172
3ERN13.74957979
4MST1R3.62035238
5LATS12.88826366
6SIK12.73612796
7FGFR42.68810139
8INSRR2.63039387
9TAOK32.58246854
10TRIB32.55321806
11EPHA22.51114893
12MAP3K22.40747135
13MST42.34291265
14LMTK22.17689529
15PTK62.06841949
16MAP3K32.02332835
17PASK1.99785239
18MAP2K21.99460325
19PKN21.95363864
20ERBB31.89567217
21IRAK31.86018464
22STK241.84949178
23ERBB41.82918804
24FER1.72291277
25MAP3K121.70214961
26MET1.56898968
27MAPK151.51887772
28STK38L1.50526264
29IRAK41.44038321
30SMG11.43090042
31EPHA31.41621270
32ACVR1B1.36977943
33RIPK11.35570712
34PIK3CG1.30433161
35FLT31.28375196
36PTK21.25892537
37MKNK21.19611598
38WNK41.16223612
39ERBB21.15902162
40EPHB11.14054165
41MAP3K101.05644555
42EPHB21.04088016
43AKT31.03038521
44MAPKAPK31.02411753
45PAK40.99605750
46DYRK1B0.98797289
47MAPK110.96651797
48STK390.96504602
49MAP2K60.92666216
50PIK3CA0.91331359
51OXSR10.91025196
52MAP2K10.90648548
53PRKG20.90544953
54NEK60.85746136
55CDK120.84181619
56DDR20.83874871
57TAOK10.79704422
58CDK60.78650047
59TYK20.76098489
60PRKAA20.76043625
61GSK3A0.73739481
62JAK20.73075713
63GRK10.72424758
64MAP3K90.71938677
65YES10.71427340
66MAP3K70.69818414
67LRRK20.69772023
68PRKCI0.68931900
69SCYL20.68765851
70MAP3K10.67981499
71FGFR20.66997747
72NUAK10.66532821
73WNK30.65432349
74RPS6KB20.65245552
75NME10.62357812
76MYLK0.61263628
77GRK60.61148414
78STK30.60841282
79NEK90.60300347
80LATS20.58912783
81ABL20.55427684
82DMPK0.55230596
83TESK10.55133511
84PDGFRA0.51965807
85PRKAA10.50893670
86IRAK10.49382493
87PAK30.49370435
88FGFR10.49087812
89MELK0.47180695
90ILK0.46960361
91STK100.46758472
92PDGFRB0.46525881
93MAP3K140.46152311
94TBK10.45982323
95MUSK0.45870044
96CAMK2D0.45276589
97PRKCE0.45103831
98DAPK20.44893350
99NTRK10.42329452
100CAMK2G0.41488215
101FGFR30.41405953
102NLK0.37895120
103TRPM70.37451287
104PDPK10.36287901
105BMPR20.36158342
106WNK10.36090198
107ROCK10.35775392
108RET0.35511661
109JAK10.34990225
110TGFBR20.34400705
111MAP2K40.34305676
112PRKCZ0.33380810
113MTOR0.33290164
114PRKD20.33281277
115EIF2AK10.33101393
116PDK20.32572558
117RPS6KA20.32397534
118PRKACG0.32337098
119CHUK0.32165713
120IGF1R0.28187525
121CDK80.27876231
122BMPR1B0.27872457
123KSR20.26161170
124HIPK20.25440886
125CASK0.24684141
126STK380.24591534
127SGK30.24587385
128EEF2K0.24515884
129PBK0.24024562
130MAP3K110.23837847
131PDK40.23710640
132PDK30.23710640
133RPS6KB10.22798931
134EIF2AK30.21390506
135MAPKAPK20.21171632
136MKNK10.20419030
137TGFBR10.20270703
138CDK90.19403993

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.60479845
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.49213287
3Nitrogen metabolism_Homo sapiens_hsa009103.02007569
4Tryptophan metabolism_Homo sapiens_hsa003802.63029821
5Arginine biosynthesis_Homo sapiens_hsa002202.51659228
6Sulfur metabolism_Homo sapiens_hsa009202.49660728
7Fatty acid degradation_Homo sapiens_hsa000712.49149901
8Pentose and glucuronate interconversions_Homo sapiens_hsa000402.48247603
9Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.39589268
10Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.39375253
11Maturity onset diabetes of the young_Homo sapiens_hsa049502.38170990
12Caffeine metabolism_Homo sapiens_hsa002322.34560789
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.34388549
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.22782758
15Histidine metabolism_Homo sapiens_hsa003402.22659941
16Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.15715585
17Fat digestion and absorption_Homo sapiens_hsa049752.12167069
18Chemical carcinogenesis_Homo sapiens_hsa052042.08633616
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.06276524
20Complement and coagulation cascades_Homo sapiens_hsa046102.04628487
21Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.92794541
22Butanoate metabolism_Homo sapiens_hsa006501.91074845
23Peroxisome_Homo sapiens_hsa041461.81255273
24Retinol metabolism_Homo sapiens_hsa008301.74212346
25Propanoate metabolism_Homo sapiens_hsa006401.73771844
26beta-Alanine metabolism_Homo sapiens_hsa004101.70978027
27PPAR signaling pathway_Homo sapiens_hsa033201.69047670
28Steroid hormone biosynthesis_Homo sapiens_hsa001401.67635246
29Folate biosynthesis_Homo sapiens_hsa007901.65024565
30Selenocompound metabolism_Homo sapiens_hsa004501.62295669
31Bile secretion_Homo sapiens_hsa049761.60642991
32Fatty acid metabolism_Homo sapiens_hsa012121.57013218
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.55637595
34Starch and sucrose metabolism_Homo sapiens_hsa005001.52105582
35Phenylalanine metabolism_Homo sapiens_hsa003601.49874637
36Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.45858702
37Vitamin digestion and absorption_Homo sapiens_hsa049771.43554454
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.35596820
39Thyroid cancer_Homo sapiens_hsa052161.35144800
40Pyruvate metabolism_Homo sapiens_hsa006201.27894128
41Tyrosine metabolism_Homo sapiens_hsa003501.26773241
42ABC transporters_Homo sapiens_hsa020101.25329556
43Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.20629427
442-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19548584
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.17527815
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.11762367
47Glutathione metabolism_Homo sapiens_hsa004801.10718144
48Staphylococcus aureus infection_Homo sapiens_hsa051501.05884395
49Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05321746
50Vibrio cholerae infection_Homo sapiens_hsa051101.03577583
51Arginine and proline metabolism_Homo sapiens_hsa003301.02540989
52Fatty acid elongation_Homo sapiens_hsa000621.02347199
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.98724003
54Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.98500701
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.95793120
56Carbon metabolism_Homo sapiens_hsa012000.95020477
57Steroid biosynthesis_Homo sapiens_hsa001000.92979743
58Ether lipid metabolism_Homo sapiens_hsa005650.92922941
59Circadian rhythm_Homo sapiens_hsa047100.90887112
60Glycerolipid metabolism_Homo sapiens_hsa005610.90291812
61Biosynthesis of amino acids_Homo sapiens_hsa012300.83896963
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82254684
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81062838
64Lysine degradation_Homo sapiens_hsa003100.80432499
65Sulfur relay system_Homo sapiens_hsa041220.73838432
66Galactose metabolism_Homo sapiens_hsa000520.72366790
67alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.71501862
68Mineral absorption_Homo sapiens_hsa049780.70574643
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69584199
70TGF-beta signaling pathway_Homo sapiens_hsa043500.68160964
71Renin-angiotensin system_Homo sapiens_hsa046140.68031148
72Adherens junction_Homo sapiens_hsa045200.67421473
73Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.66599571
74Insulin secretion_Homo sapiens_hsa049110.64358659
75Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.63449902
76Linoleic acid metabolism_Homo sapiens_hsa005910.63306684
77Protein digestion and absorption_Homo sapiens_hsa049740.63253159
78Insulin signaling pathway_Homo sapiens_hsa049100.62258618
79Endometrial cancer_Homo sapiens_hsa052130.60692439
80Renin secretion_Homo sapiens_hsa049240.60018035
81Hippo signaling pathway_Homo sapiens_hsa043900.59576423
82Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57832479
83Leukocyte transendothelial migration_Homo sapiens_hsa046700.52934056
84Type II diabetes mellitus_Homo sapiens_hsa049300.52729427
85Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51304808
86Pentose phosphate pathway_Homo sapiens_hsa000300.50465234
87Fructose and mannose metabolism_Homo sapiens_hsa000510.50309374
88SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47974618
89Proteoglycans in cancer_Homo sapiens_hsa052050.47887354
90Fatty acid biosynthesis_Homo sapiens_hsa000610.47719375
91Metabolic pathways_Homo sapiens_hsa011000.47493047
92Inositol phosphate metabolism_Homo sapiens_hsa005620.46563404
93Renal cell carcinoma_Homo sapiens_hsa052110.44783921
94Dorso-ventral axis formation_Homo sapiens_hsa043200.39840684
95Prostate cancer_Homo sapiens_hsa052150.39662227
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38560441
97Insulin resistance_Homo sapiens_hsa049310.37734303
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34753784
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34132000
100Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33621480
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33219370
102Pancreatic secretion_Homo sapiens_hsa049720.33214162
103Basal cell carcinoma_Homo sapiens_hsa052170.33071498
104Protein export_Homo sapiens_hsa030600.32195776
105Chronic myeloid leukemia_Homo sapiens_hsa052200.31768423
106Amoebiasis_Homo sapiens_hsa051460.31252392
107Prolactin signaling pathway_Homo sapiens_hsa049170.30608006
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29661987
109Ovarian steroidogenesis_Homo sapiens_hsa049130.29212827
110One carbon pool by folate_Homo sapiens_hsa006700.28961138
111Choline metabolism in cancer_Homo sapiens_hsa052310.28433047
112Arachidonic acid metabolism_Homo sapiens_hsa005900.26798744
113Vitamin B6 metabolism_Homo sapiens_hsa007500.25878626
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.23113378
115Thyroid hormone synthesis_Homo sapiens_hsa049180.19622404
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.18269469
117Sphingolipid metabolism_Homo sapiens_hsa006000.16105680
118Other glycan degradation_Homo sapiens_hsa005110.12193793
119Bladder cancer_Homo sapiens_hsa052190.11422251
120Glucagon signaling pathway_Homo sapiens_hsa049220.09433508
121Hepatitis C_Homo sapiens_hsa051600.08260526
122AMPK signaling pathway_Homo sapiens_hsa041520.03977994
123Glycosaminoglycan degradation_Homo sapiens_hsa005310.03899554
124Prion diseases_Homo sapiens_hsa050200.03145829
125Tight junction_Homo sapiens_hsa045300.02590007
126N-Glycan biosynthesis_Homo sapiens_hsa005100.00857874
127Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563-0.0296403
128Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603-0.0259003
129Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960-0.0134660

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