Rank | Gene Set | Z-score |
---|---|---|
1 | muscle filament sliding (GO:0030049) | 7.35786809 |
2 | actin-myosin filament sliding (GO:0033275) | 7.35786809 |
3 | regulation of skeletal muscle contraction (GO:0014819) | 6.77302685 |
4 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 6.64807118 |
5 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 6.51832611 |
6 | sarcomere organization (GO:0045214) | 6.28460529 |
7 | actin-mediated cell contraction (GO:0070252) | 6.03676724 |
8 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 5.91621310 |
9 | plasma membrane repair (GO:0001778) | 5.79974038 |
10 | skeletal muscle contraction (GO:0003009) | 5.69955972 |
11 | myofibril assembly (GO:0030239) | 5.59558769 |
12 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 5.56557598 |
13 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 5.38979799 |
14 | regulation of cell communication by electrical coupling (GO:0010649) | 5.30983752 |
15 | cardiac myofibril assembly (GO:0055003) | 5.26768304 |
16 | striated muscle contraction (GO:0006941) | 5.14166206 |
17 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 5.04735140 |
18 | cardiac muscle contraction (GO:0060048) | 4.91883112 |
19 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.90882131 |
20 | tricarboxylic acid cycle (GO:0006099) | 4.84296327 |
21 | glycogen biosynthetic process (GO:0005978) | 4.78676282 |
22 | glucan biosynthetic process (GO:0009250) | 4.78676282 |
23 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 4.74136555 |
24 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.63307880 |
25 | regulation of relaxation of muscle (GO:1901077) | 4.61264215 |
26 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.58894418 |
27 | skeletal muscle tissue development (GO:0007519) | 4.54992345 |
28 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.54329930 |
29 | actin filament-based movement (GO:0030048) | 4.44685605 |
30 | regulation of actin filament-based movement (GO:1903115) | 4.30045284 |
31 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 4.28630070 |
32 | regulation of membrane repolarization (GO:0060306) | 4.28627165 |
33 | skeletal muscle adaptation (GO:0043501) | 4.23082772 |
34 | actomyosin structure organization (GO:0031032) | 4.21979904 |
35 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.21056033 |
36 | regulation of cofactor metabolic process (GO:0051193) | 4.20464949 |
37 | regulation of coenzyme metabolic process (GO:0051196) | 4.20464949 |
38 | skeletal muscle tissue regeneration (GO:0043403) | 4.09563883 |
39 | carnitine shuttle (GO:0006853) | 4.08460041 |
40 | 2-oxoglutarate metabolic process (GO:0006103) | 3.91355940 |
41 | fructose metabolic process (GO:0006000) | 3.89911924 |
42 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.89078773 |
43 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.88904789 |
44 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.88904789 |
45 | regulation of striated muscle contraction (GO:0006942) | 3.87682644 |
46 | muscle contraction (GO:0006936) | 3.84135915 |
47 | muscle organ morphogenesis (GO:0048644) | 3.82102015 |
48 | creatine metabolic process (GO:0006600) | 3.79183312 |
49 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.78200742 |
50 | response to inactivity (GO:0014854) | 3.77873157 |
51 | regulation of sarcomere organization (GO:0060297) | 3.77829641 |
52 | glycogen metabolic process (GO:0005977) | 3.77337254 |
53 | gluconeogenesis (GO:0006094) | 3.74821238 |
54 | muscle organ development (GO:0007517) | 3.74179892 |
55 | muscle structure development (GO:0061061) | 3.73628961 |
56 | muscle cell fate commitment (GO:0042693) | 3.73583628 |
57 | neuromuscular synaptic transmission (GO:0007274) | 3.72500641 |
58 | glucan metabolic process (GO:0044042) | 3.68857894 |
59 | cellular glucan metabolic process (GO:0006073) | 3.68857894 |
60 | cardiac muscle hypertrophy (GO:0003300) | 3.67248944 |
61 | positive regulation of myotube differentiation (GO:0010831) | 3.65941742 |
62 | glycogen catabolic process (GO:0005980) | 3.64471869 |
63 | cardiac muscle cell development (GO:0055013) | 3.63341038 |
64 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.63266148 |
65 | striated muscle hypertrophy (GO:0014897) | 3.62702766 |
66 | response to activity (GO:0014823) | 3.56720599 |
67 | NADH metabolic process (GO:0006734) | 3.53169621 |
68 | neuronal action potential propagation (GO:0019227) | 3.51709706 |
69 | muscle system process (GO:0003012) | 3.51420585 |
70 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.45669249 |
71 | cell communication involved in cardiac conduction (GO:0086065) | 3.45418018 |
72 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.44990521 |
73 | regulation of skeletal muscle cell differentiation (GO:2001014) | 3.44277050 |
74 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.42954250 |
75 | cell communication by electrical coupling (GO:0010644) | 3.42655849 |
76 | striated muscle adaptation (GO:0014888) | 3.42629761 |
77 | detection of calcium ion (GO:0005513) | 3.41783917 |
78 | muscle adaptation (GO:0043500) | 3.40659084 |
79 | skeletal muscle fiber development (GO:0048741) | 3.40068508 |
80 | glucan catabolic process (GO:0009251) | 3.38157352 |
81 | muscle cell cellular homeostasis (GO:0046716) | 3.37371908 |
82 | myoblast fusion (GO:0007520) | 3.36241986 |
83 | relaxation of muscle (GO:0090075) | 3.35823642 |
84 | cardiac cell development (GO:0055006) | 3.35759625 |
85 | hexose biosynthetic process (GO:0019319) | 3.34529877 |
86 | fatty acid transmembrane transport (GO:1902001) | 3.33768584 |
87 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.32257613 |
88 | positive regulation of cation channel activity (GO:2001259) | 3.30280125 |
89 | ubiquinone biosynthetic process (GO:0006744) | 3.28737855 |
90 | negative regulation of muscle contraction (GO:0045932) | 3.26706741 |
91 | cardiac muscle cell action potential (GO:0086001) | 3.26217500 |
92 | regulation of sulfur metabolic process (GO:0042762) | 3.24481003 |
93 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.23946787 |
94 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.22484983 |
95 | muscle fiber development (GO:0048747) | 3.22408004 |
96 | negative regulation of potassium ion transport (GO:0043267) | 3.21672770 |
97 | regulation of the force of heart contraction (GO:0002026) | 3.21574711 |
98 | myotube differentiation (GO:0014902) | 3.19669393 |
99 | negative regulation of protein localization to cell surface (GO:2000009) | 3.19124536 |
100 | adult heart development (GO:0007512) | 3.19019915 |
101 | membrane depolarization during action potential (GO:0086010) | 3.18335433 |
102 | regulation of cation channel activity (GO:2001257) | 3.18106911 |
103 | response to muscle activity (GO:0014850) | 3.17589814 |
104 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.17505190 |
105 | muscle atrophy (GO:0014889) | 3.16092276 |
106 | muscle hypertrophy (GO:0014896) | 3.13343863 |
107 | cellular carbohydrate catabolic process (GO:0044275) | 3.12566974 |
108 | muscle cell development (GO:0055001) | 3.12205728 |
109 | regulation of sequestering of triglyceride (GO:0010889) | 3.11537227 |
110 | cellular polysaccharide catabolic process (GO:0044247) | 3.11225437 |
111 | striated muscle tissue development (GO:0014706) | 3.11125928 |
112 | cardiac conduction (GO:0061337) | 3.08638104 |
113 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.07129926 |
114 | heart contraction (GO:0060047) | 3.05027523 |
115 | heart process (GO:0003015) | 3.05027523 |
116 | myotube cell development (GO:0014904) | 3.04991503 |
117 | regulation of muscle system process (GO:0090257) | 3.03487600 |
118 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.02169875 |
119 | succinate metabolic process (GO:0006105) | 3.00549486 |
120 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.00378958 |
121 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.00378958 |
122 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.99953003 |
123 | muscle hypertrophy in response to stress (GO:0003299) | 2.99953003 |
124 | cardiac muscle adaptation (GO:0014887) | 2.99953003 |
125 | muscle tissue morphogenesis (GO:0060415) | 2.99140821 |
126 | regulation of synapse structural plasticity (GO:0051823) | 2.97437816 |
127 | potassium ion import (GO:0010107) | 2.96479590 |
128 | striated muscle cell development (GO:0055002) | 2.95969546 |
129 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.93995276 |
130 | polysaccharide catabolic process (GO:0000272) | 2.93708926 |
131 | striated muscle atrophy (GO:0014891) | 2.93264613 |
132 | regulation of cardiac muscle contraction (GO:0055117) | 2.92964558 |
133 | carnitine transmembrane transport (GO:1902603) | 2.92503116 |
134 | respiratory electron transport chain (GO:0022904) | 2.90778868 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.96776718 |
2 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.97135552 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.63841267 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.48769128 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.47456173 |
6 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.36196928 |
7 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.29450357 |
8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.26536551 |
9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.15866325 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.15866325 |
11 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.13366272 |
12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.12483894 |
13 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.11969506 |
14 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.09102660 |
15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.07220812 |
16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.04120983 |
17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.99733574 |
18 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.99661405 |
19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.97870998 |
20 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.88926044 |
21 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.85361140 |
22 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.84370900 |
23 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.79458914 |
24 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.78733439 |
25 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.76650091 |
26 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.76650091 |
27 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.74251060 |
28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.73734980 |
29 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.72029884 |
30 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.71304446 |
31 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.71276723 |
32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.64423892 |
33 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.63791299 |
34 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.56677245 |
35 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.56480814 |
36 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.55524557 |
37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.45338280 |
38 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.38575955 |
39 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.38396272 |
40 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.36722040 |
41 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.35228057 |
42 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.34285706 |
43 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.33772906 |
44 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.32475019 |
45 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.30572350 |
46 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.29842656 |
47 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.25865662 |
48 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.25633399 |
49 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.24922588 |
50 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.24543580 |
51 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.24296635 |
52 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.23402209 |
53 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22636098 |
54 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.21044524 |
55 | VDR_22108803_ChIP-Seq_LS180_Human | 1.20058439 |
56 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.17516198 |
57 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.16489842 |
58 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.15544568 |
59 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.14497756 |
60 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13181107 |
61 | SA1_27219007_Chip-Seq_Bcells_Human | 1.12716401 |
62 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.08419520 |
63 | AR_19668381_ChIP-Seq_PC3_Human | 1.07282341 |
64 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.07242435 |
65 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.06701580 |
66 | AR_25329375_ChIP-Seq_VCAP_Human | 1.06552919 |
67 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.06213951 |
68 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.04262499 |
69 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.04160384 |
70 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 1.03079521 |
71 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.01719014 |
72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.01097783 |
73 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.00358048 |
74 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.00235680 |
75 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.99868900 |
76 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.99840706 |
77 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.99740725 |
78 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.98510022 |
79 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.98292463 |
80 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.97702592 |
81 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.97677660 |
82 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.97668974 |
83 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97583815 |
84 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.97336451 |
85 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.97213182 |
86 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.97073828 |
87 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.96993335 |
88 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.96913555 |
89 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.96784051 |
90 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96587113 |
91 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.96307860 |
92 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.95765681 |
93 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.95700634 |
94 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.94530188 |
95 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.92498626 |
96 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.92423459 |
97 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.92358469 |
98 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.91924766 |
99 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.91915707 |
100 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.91594973 |
101 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.91495468 |
102 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.89888400 |
103 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.89346918 |
104 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.88908154 |
105 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88833680 |
106 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.88510992 |
107 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.87762478 |
108 | STAT3_23295773_ChIP-Seq_U87_Human | 0.87679138 |
109 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.87260254 |
110 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.87181586 |
111 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.87155996 |
112 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.87121683 |
113 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87097224 |
114 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.86699632 |
115 | * TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.86114060 |
116 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.85977211 |
117 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.85587543 |
118 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.85587543 |
119 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.85110563 |
120 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84862519 |
121 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.84721173 |
122 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.83648803 |
123 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.83223203 |
124 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.83216909 |
125 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.82995999 |
126 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.82987112 |
127 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.82911994 |
128 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.82763455 |
129 | TCF4_23295773_ChIP-Seq_U87_Human | 0.82721230 |
130 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.82595708 |
131 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.82009186 |
132 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.81855514 |
133 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.81597119 |
134 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.81152570 |
135 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.81104786 |
136 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.80844790 |
137 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.79872059 |
138 | KDM2B_26808549_Chip-Seq_K562_Human | 0.79641809 |
139 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.78377133 |
140 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.78377133 |
141 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.78257922 |
142 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.76678058 |
143 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.76010199 |
144 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.75919729 |
145 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.75625118 |
146 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.74668174 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 5.60933416 |
2 | MP0002837_dystrophic_cardiac_calcinosis | 5.44911178 |
3 | MP0000751_myopathy | 5.33108996 |
4 | MP0004145_abnormal_muscle_electrophysio | 4.70795351 |
5 | MP0000749_muscle_degeneration | 4.59305390 |
6 | MP0004036_abnormal_muscle_relaxation | 3.96296580 |
7 | MP0004084_abnormal_cardiac_muscle | 3.63052211 |
8 | * MP0004215_abnormal_myocardial_fiber | 3.09139763 |
9 | MP0005451_abnormal_body_composition | 3.06148268 |
10 | MP0000747_muscle_weakness | 2.91312117 |
11 | * MP0002106_abnormal_muscle_physiology | 2.89426820 |
12 | * MP0004087_abnormal_muscle_fiber | 2.78725379 |
13 | MP0005620_abnormal_muscle_contractility | 2.76626239 |
14 | MP0004130_abnormal_muscle_cell | 2.62772110 |
15 | MP0005330_cardiomyopathy | 2.61320467 |
16 | MP0002269_muscular_atrophy | 2.60931532 |
17 | MP0000759_abnormal_skeletal_muscle | 2.57286719 |
18 | MP0000750_abnormal_muscle_regeneration | 2.52470451 |
19 | * MP0005369_muscle_phenotype | 2.42112490 |
20 | MP0004233_abnormal_muscle_weight | 2.41570283 |
21 | MP0004859_abnormal_synaptic_plasticity | 2.36895583 |
22 | MP0002972_abnormal_cardiac_muscle | 2.19658473 |
23 | MP0004270_analgesia | 2.11799253 |
24 | MP0004484_altered_response_of | 2.08805195 |
25 | MP0003137_abnormal_impulse_conducting | 2.02344204 |
26 | MP0002332_abnormal_exercise_endurance | 1.80380697 |
27 | MP0008775_abnormal_heart_ventricle | 1.72144761 |
28 | MP0003880_abnormal_central_pattern | 1.69791371 |
29 | MP0006036_abnormal_mitochondrial_physio | 1.63842782 |
30 | MP0002822_catalepsy | 1.62582133 |
31 | MP0001544_abnormal_cardiovascular_syste | 1.58029070 |
32 | MP0005385_cardiovascular_system_phenoty | 1.58029070 |
33 | MP0003635_abnormal_synaptic_transmissio | 1.56774161 |
34 | * MP0004085_abnormal_heartbeat | 1.45696538 |
35 | * MP0010630_abnormal_cardiac_muscle | 1.45605497 |
36 | MP0006138_congestive_heart_failure | 1.38919016 |
37 | MP0002108_abnormal_muscle_morphology | 1.31606428 |
38 | MP0009745_abnormal_behavioral_response | 1.30120363 |
39 | MP0009046_muscle_twitch | 1.27926397 |
40 | MP0000013_abnormal_adipose_tissue | 1.24918362 |
41 | MP0003221_abnormal_cardiomyocyte_apopto | 1.24431142 |
42 | MP0002064_seizures | 1.19701139 |
43 | MP0009780_abnormal_chondrocyte_physiolo | 1.18899392 |
44 | MP0002063_abnormal_learning/memory/cond | 1.16891329 |
45 | MP0002734_abnormal_mechanical_nocicepti | 1.13480977 |
46 | MP0002272_abnormal_nervous_system | 1.12836939 |
47 | MP0002909_abnormal_adrenal_gland | 1.12734199 |
48 | MP0006035_abnormal_mitochondrial_morpho | 1.11941379 |
49 | MP0004510_myositis | 1.11677965 |
50 | MP0008569_lethality_at_weaning | 1.10175393 |
51 | MP0002234_abnormal_pharynx_morphology | 1.07118847 |
52 | MP0004043_abnormal_pH_regulation | 1.05965050 |
53 | MP0002127_abnormal_cardiovascular_syste | 1.03329850 |
54 | MP0003950_abnormal_plasma_membrane | 1.01644180 |
55 | MP0005666_abnormal_adipose_tissue | 0.99616992 |
56 | MP0001968_abnormal_touch/_nociception | 0.95333536 |
57 | MP0001440_abnormal_grooming_behavior | 0.94204118 |
58 | MP0000733_abnormal_muscle_development | 0.93415302 |
59 | MP0002067_abnormal_sensory_capabilities | 0.93330720 |
60 | MP0001661_extended_life_span | 0.91337056 |
61 | MP0002572_abnormal_emotion/affect_behav | 0.91107717 |
62 | MP0004924_abnormal_behavior | 0.86455055 |
63 | MP0005386_behavior/neurological_phenoty | 0.86455055 |
64 | MP0004185_abnormal_adipocyte_glucose | 0.86440458 |
65 | MP0002735_abnormal_chemical_nociception | 0.84603279 |
66 | MP0005266_abnormal_metabolism | 0.82307566 |
67 | MP0001486_abnormal_startle_reflex | 0.80535269 |
68 | MP0003828_pulmonary_edema | 0.79925059 |
69 | MP0005375_adipose_tissue_phenotype | 0.77962841 |
70 | MP0002736_abnormal_nociception_after | 0.76541676 |
71 | MP0003329_amyloid_beta_deposits | 0.73587675 |
72 | MP0001529_abnormal_vocalization | 0.70724816 |
73 | MP0003045_fibrosis | 0.70349228 |
74 | MP0002971_abnormal_brown_adipose | 0.69374637 |
75 | MP0004142_abnormal_muscle_tone | 0.68602844 |
76 | MP0000230_abnormal_systemic_arterial | 0.68220010 |
77 | MP0001984_abnormal_olfaction | 0.68024277 |
78 | MP0002066_abnormal_motor_capabilities/c | 0.67750305 |
79 | MP0005670_abnormal_white_adipose | 0.66496265 |
80 | MP0004858_abnormal_nervous_system | 0.65683097 |
81 | MP0000372_irregular_coat_pigmentation | 0.65223153 |
82 | MP0001970_abnormal_pain_threshold | 0.64866859 |
83 | MP0003879_abnormal_hair_cell | 0.64784571 |
84 | MP0001501_abnormal_sleep_pattern | 0.64497088 |
85 | MP0008961_abnormal_basal_metabolism | 0.64439565 |
86 | MP0002184_abnormal_innervation | 0.63436626 |
87 | MP0002638_abnormal_pupillary_reflex | 0.60112307 |
88 | * MP0000266_abnormal_heart_morphology | 0.60101260 |
89 | MP0005535_abnormal_body_temperature | 0.59850695 |
90 | MP0002078_abnormal_glucose_homeostasis | 0.59655060 |
91 | MP0000003_abnormal_adipose_tissue | 0.59236381 |
92 | MP0001346_abnormal_lacrimal_gland | 0.57414830 |
93 | MP0003633_abnormal_nervous_system | 0.57308023 |
94 | MP0005167_abnormal_blood-brain_barrier | 0.57065915 |
95 | MP0005646_abnormal_pituitary_gland | 0.57017390 |
96 | MP0001299_abnormal_eye_distance/ | 0.56595745 |
97 | MP0002733_abnormal_thermal_nociception | 0.55585446 |
98 | MP0002876_abnormal_thyroid_physiology | 0.55504486 |
99 | MP0005165_increased_susceptibility_to | 0.55392796 |
100 | MP0001502_abnormal_circadian_rhythm | 0.52038842 |
101 | MP0005423_abnormal_somatic_nervous | 0.51908491 |
102 | MP0004147_increased_porphyrin_level | 0.51722303 |
103 | MP0002090_abnormal_vision | 0.51442299 |
104 | MP0004811_abnormal_neuron_physiology | 0.51357305 |
105 | MP0005083_abnormal_biliary_tract | 0.50718666 |
106 | MP0002882_abnormal_neuron_morphology | 0.49947861 |
107 | MP0005645_abnormal_hypothalamus_physiol | 0.49669838 |
108 | MP0005623_abnormal_meninges_morphology | 0.49499077 |
109 | MP0004134_abnormal_chest_morphology | 0.48899026 |
110 | MP0000955_abnormal_spinal_cord | 0.48713441 |
111 | MP0006276_abnormal_autonomic_nervous | 0.48483531 |
112 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.41493582 |
113 | MP0005332_abnormal_amino_acid | 0.40837014 |
114 | MP0003656_abnormal_erythrocyte_physiolo | 0.40393820 |
115 | MP0005452_abnormal_adipose_tissue | 0.38353349 |
116 | MP0005166_decreased_susceptibility_to | 0.36321132 |
117 | MP0005376_homeostasis/metabolism_phenot | 0.33218569 |
118 | MP0009672_abnormal_birth_weight | 0.31315015 |
119 | MP0001943_abnormal_respiration | 0.30095861 |
120 | MP0005187_abnormal_penis_morphology | 0.30011646 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Exercise-induced myalgia (HP:0003738) | 7.66669099 |
2 | Exercise-induced muscle cramps (HP:0003710) | 6.85973636 |
3 | Muscle hypertrophy of the lower extremities (HP:0008968) | 6.53847005 |
4 | Muscle fiber inclusion bodies (HP:0100299) | 6.43902669 |
5 | Calf muscle hypertrophy (HP:0008981) | 6.35402297 |
6 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 6.19358455 |
7 | Nemaline bodies (HP:0003798) | 5.64264293 |
8 | Sudden death (HP:0001699) | 5.32969033 |
9 | Muscle fiber splitting (HP:0003555) | 5.17438762 |
10 | Type 1 muscle fiber predominance (HP:0003803) | 5.01779962 |
11 | Myoglobinuria (HP:0002913) | 4.92285991 |
12 | Abnormality of the calf musculature (HP:0001430) | 4.90846888 |
13 | Hyporeflexia of lower limbs (HP:0002600) | 4.72943350 |
14 | Distal arthrogryposis (HP:0005684) | 4.50888443 |
15 | Difficulty running (HP:0009046) | 4.49640454 |
16 | EMG: myopathic abnormalities (HP:0003458) | 4.48815590 |
17 | Myotonia (HP:0002486) | 4.13873894 |
18 | Myopathic facies (HP:0002058) | 4.11198501 |
19 | Round ear (HP:0100830) | 3.92893725 |
20 | Subaortic stenosis (HP:0001682) | 3.83664769 |
21 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.83664769 |
22 | Ventricular tachycardia (HP:0004756) | 3.77162073 |
23 | Increased connective tissue (HP:0009025) | 3.73152452 |
24 | Muscle stiffness (HP:0003552) | 3.67995809 |
25 | Rhabdomyolysis (HP:0003201) | 3.63973161 |
26 | Atrial fibrillation (HP:0005110) | 3.47301048 |
27 | Ulnar deviation of the wrist (HP:0003049) | 3.34117529 |
28 | Abnormality of skeletal muscle fiber size (HP:0012084) | 3.29255808 |
29 | Primary atrial arrhythmia (HP:0001692) | 3.28025928 |
30 | Asymmetric septal hypertrophy (HP:0001670) | 3.24789607 |
31 | Increased variability in muscle fiber diameter (HP:0003557) | 3.23903565 |
32 | Difficulty climbing stairs (HP:0003551) | 3.20470552 |
33 | Supraventricular tachycardia (HP:0004755) | 3.13834551 |
34 | Bundle branch block (HP:0011710) | 3.13626820 |
35 | Supraventricular arrhythmia (HP:0005115) | 3.05575382 |
36 | Neck muscle weakness (HP:0000467) | 2.97968922 |
37 | Lipoatrophy (HP:0100578) | 2.97109795 |
38 | Prolonged QT interval (HP:0001657) | 2.95237737 |
39 | Rimmed vacuoles (HP:0003805) | 2.90957005 |
40 | Syncope (HP:0001279) | 2.90600764 |
41 | Focal motor seizures (HP:0011153) | 2.89107319 |
42 | Calcaneovalgus deformity (HP:0001848) | 2.81492277 |
43 | Palpitations (HP:0001962) | 2.80056892 |
44 | Areflexia of lower limbs (HP:0002522) | 2.69572910 |
45 | Absent phalangeal crease (HP:0006109) | 2.62853190 |
46 | Dilated cardiomyopathy (HP:0001644) | 2.62486748 |
47 | Ventricular arrhythmia (HP:0004308) | 2.60683440 |
48 | Right ventricular cardiomyopathy (HP:0011663) | 2.57858588 |
49 | Deformed tarsal bones (HP:0008119) | 2.57581442 |
50 | Ventricular fibrillation (HP:0001663) | 2.48701421 |
51 | Heart block (HP:0012722) | 2.48625510 |
52 | Weak cry (HP:0001612) | 2.47352302 |
53 | Slender build (HP:0001533) | 2.43183682 |
54 | Distal lower limb muscle weakness (HP:0009053) | 2.42939598 |
55 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.38212430 |
56 | Left ventricular hypertrophy (HP:0001712) | 2.35234595 |
57 | EMG: neuropathic changes (HP:0003445) | 2.33713220 |
58 | Abnormal atrioventricular conduction (HP:0005150) | 2.32932053 |
59 | Abnormal EKG (HP:0003115) | 2.32196528 |
60 | Acute necrotizing encephalopathy (HP:0006965) | 2.30384346 |
61 | Pheochromocytoma (HP:0002666) | 2.29815354 |
62 | Limb-girdle muscle atrophy (HP:0003797) | 2.28937955 |
63 | Gowers sign (HP:0003391) | 2.27878964 |
64 | Shoulder girdle muscle weakness (HP:0003547) | 2.27413784 |
65 | Muscular dystrophy (HP:0003560) | 2.26209259 |
66 | Frequent falls (HP:0002359) | 2.25505592 |
67 | Abnormality of the calcaneus (HP:0008364) | 2.22750711 |
68 | Progressive muscle weakness (HP:0003323) | 2.22741551 |
69 | Distal lower limb amyotrophy (HP:0008944) | 2.20750853 |
70 | Malignant hyperthermia (HP:0002047) | 2.19117726 |
71 | Central scotoma (HP:0000603) | 2.16900045 |
72 | Fetal akinesia sequence (HP:0001989) | 2.15843385 |
73 | Abnormal finger flexion creases (HP:0006143) | 2.14874641 |
74 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.14678223 |
75 | Atrioventricular block (HP:0001678) | 2.11889705 |
76 | Hip contracture (HP:0003273) | 2.11719897 |
77 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.11331113 |
78 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.11331113 |
79 | Hyperkalemia (HP:0002153) | 2.10206381 |
80 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.08373742 |
81 | Neuroendocrine neoplasm (HP:0100634) | 2.04602406 |
82 | Abnormality of the neuromuscular junction (HP:0003398) | 2.04377261 |
83 | Fatigable weakness (HP:0003473) | 2.04377261 |
84 | Generalized muscle weakness (HP:0003324) | 2.02158896 |
85 | Pelvic girdle muscle weakness (HP:0003749) | 2.01196365 |
86 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.00757545 |
87 | Abnormality of alanine metabolism (HP:0010916) | 2.00757545 |
88 | Hyperalaninemia (HP:0003348) | 2.00757545 |
89 | Hypoplastic ischia (HP:0003175) | 1.99522100 |
90 | Facial diplegia (HP:0001349) | 1.99413994 |
91 | Dysmetric saccades (HP:0000641) | 1.99012642 |
92 | Waddling gait (HP:0002515) | 1.98369378 |
93 | Bulbar palsy (HP:0001283) | 1.98305849 |
94 | Spinal rigidity (HP:0003306) | 1.98143025 |
95 | Proximal amyotrophy (HP:0007126) | 1.96725676 |
96 | Abnormality of the foot musculature (HP:0001436) | 1.95978576 |
97 | Progressive macrocephaly (HP:0004481) | 1.95202115 |
98 | Visual hallucinations (HP:0002367) | 1.94881751 |
99 | Lower limb amyotrophy (HP:0007210) | 1.92975683 |
100 | Limb-girdle muscle weakness (HP:0003325) | 1.91493633 |
101 | Scapular winging (HP:0003691) | 1.90678060 |
102 | Exercise intolerance (HP:0003546) | 1.89707012 |
103 | Acute encephalopathy (HP:0006846) | 1.87350360 |
104 | Hepatocellular necrosis (HP:0001404) | 1.86436557 |
105 | Atonic seizures (HP:0010819) | 1.85717811 |
106 | Ketoacidosis (HP:0001993) | 1.84335555 |
107 | Hepatic necrosis (HP:0002605) | 1.84127191 |
108 | Mitochondrial inheritance (HP:0001427) | 1.82933641 |
109 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.81325578 |
110 | Foot dorsiflexor weakness (HP:0009027) | 1.80054986 |
111 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.79297495 |
112 | Nonprogressive disorder (HP:0003680) | 1.78592314 |
113 | Ragged-red muscle fibers (HP:0003200) | 1.75181852 |
114 | Popliteal pterygium (HP:0009756) | 1.73086918 |
115 | Metatarsus adductus (HP:0001840) | 1.69169899 |
116 | Type 2 muscle fiber atrophy (HP:0003554) | 1.67020484 |
117 | Increased intramyocellular lipid droplets (HP:0012240) | 1.65132183 |
118 | Paralysis (HP:0003470) | 1.64302505 |
119 | Long clavicles (HP:0000890) | 1.57595301 |
120 | Ulnar deviation of finger (HP:0009465) | 1.55466186 |
121 | Muscle fiber atrophy (HP:0100295) | 1.52569856 |
122 | Increased muscle lipid content (HP:0009058) | 1.51497070 |
123 | Oligomenorrhea (HP:0000876) | 1.40751892 |
124 | Limited hip movement (HP:0008800) | 1.40081865 |
125 | Ulnar deviation of the hand or of fingers of the hand (HP:0001193) | 1.33372847 |
126 | Adducted thumb (HP:0001181) | 1.33280576 |
127 | Steppage gait (HP:0003376) | 1.32533519 |
128 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.28709210 |
129 | Abnormality of potassium homeostasis (HP:0011042) | 1.27997565 |
130 | Neonatal hypotonia (HP:0001319) | 1.26061101 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 5.83860519 |
2 | TTN | 5.09378800 |
3 | PHKG2 | 4.87836906 |
4 | PHKG1 | 4.87836906 |
5 | PDK3 | 2.79849838 |
6 | PDK4 | 2.79849838 |
7 | NME1 | 2.60679227 |
8 | NEK1 | 2.44410593 |
9 | PINK1 | 2.33460115 |
10 | DMPK | 2.05639611 |
11 | LMTK2 | 2.04853506 |
12 | MUSK | 1.98440110 |
13 | EPHA4 | 1.79317410 |
14 | MAP2K4 | 1.78515950 |
15 | MAP3K4 | 1.71472148 |
16 | PIK3CA | 1.70895715 |
17 | PDK2 | 1.69063437 |
18 | NTRK3 | 1.66105228 |
19 | PIK3CG | 1.59967172 |
20 | MAP3K7 | 1.59112643 |
21 | MYLK | 1.53476252 |
22 | TRIB3 | 1.48294881 |
23 | BCKDK | 1.32121457 |
24 | MAPK12 | 1.30460918 |
25 | CASK | 1.23309910 |
26 | PAK6 | 1.18874495 |
27 | MAP2K7 | 1.16830757 |
28 | PKN2 | 1.10089971 |
29 | MAP3K9 | 1.09398955 |
30 | CAMK2D | 1.05209668 |
31 | TRPM7 | 1.03794237 |
32 | MAP2K3 | 1.03208362 |
33 | STK24 | 1.02111426 |
34 | EEF2K | 0.99579902 |
35 | LIMK1 | 0.99294883 |
36 | DAPK2 | 0.95182335 |
37 | KSR2 | 0.94898369 |
38 | PAK3 | 0.89020194 |
39 | MAP3K13 | 0.88701808 |
40 | CAMK2A | 0.86316500 |
41 | STK38 | 0.85899892 |
42 | PRKD3 | 0.83473153 |
43 | PRPF4B | 0.79454149 |
44 | GRK7 | 0.79038798 |
45 | PRKAA1 | 0.77556367 |
46 | MOS | 0.76088375 |
47 | MINK1 | 0.75896620 |
48 | MAP3K12 | 0.73447786 |
49 | CAMK2G | 0.73090816 |
50 | INSRR | 0.72683150 |
51 | MARK1 | 0.69705378 |
52 | PTK2B | 0.67771118 |
53 | MAP2K6 | 0.65053217 |
54 | DYRK1B | 0.63713627 |
55 | ROCK1 | 0.62993968 |
56 | ERBB3 | 0.61487697 |
57 | TIE1 | 0.60789449 |
58 | PRKAA2 | 0.59448666 |
59 | CAMK1 | 0.59333503 |
60 | PLK2 | 0.59233961 |
61 | MAP3K5 | 0.57441857 |
62 | PRKD1 | 0.57124641 |
63 | CDK5 | 0.55869624 |
64 | MAPK7 | 0.55558781 |
65 | SGK1 | 0.55185977 |
66 | CDK19 | 0.54713363 |
67 | MAPK11 | 0.52866602 |
68 | KSR1 | 0.51834549 |
69 | CDC42BPA | 0.51190552 |
70 | ILK | 0.50625499 |
71 | PKN1 | 0.50160336 |
72 | GRK5 | 0.49923756 |
73 | ROCK2 | 0.49793257 |
74 | PDPK1 | 0.49502305 |
75 | MAPKAPK3 | 0.49065594 |
76 | CAMK2B | 0.47823928 |
77 | SGK2 | 0.46767941 |
78 | FER | 0.46214567 |
79 | STK38L | 0.45926062 |
80 | PRKACB | 0.45856215 |
81 | MAPK4 | 0.45500463 |
82 | CAMK4 | 0.45374920 |
83 | SGK223 | 0.45178275 |
84 | SGK494 | 0.45178275 |
85 | PRKACA | 0.44820960 |
86 | SGK3 | 0.44801086 |
87 | PRKCE | 0.44780480 |
88 | PDK1 | 0.44478645 |
89 | TAOK2 | 0.43600254 |
90 | MAP3K1 | 0.43488969 |
91 | TAOK1 | 0.42379730 |
92 | DAPK3 | 0.42146683 |
93 | WNK1 | 0.41207695 |
94 | NTRK1 | 0.40801026 |
95 | RET | 0.40752910 |
96 | PRKCG | 0.40265718 |
97 | RIPK1 | 0.39856003 |
98 | MAP3K6 | 0.39500172 |
99 | LATS2 | 0.38834009 |
100 | PRKCH | 0.38089869 |
101 | CCNB1 | 0.37870402 |
102 | RPS6KA3 | 0.37712572 |
103 | CAMKK1 | 0.36686972 |
104 | MAP2K1 | 0.36590222 |
105 | NTRK2 | 0.36564309 |
106 | MAPK13 | 0.36554342 |
107 | WNK4 | 0.36113621 |
108 | ARAF | 0.35706765 |
109 | NEK9 | 0.35545476 |
110 | AKT2 | 0.33842980 |
111 | PRKG1 | 0.33261326 |
112 | MAPK10 | 0.26928788 |
113 | STK11 | 0.25096570 |
114 | RPS6KB1 | 0.23961537 |
115 | MARK2 | 0.23032466 |
116 | TBK1 | 0.21767004 |
117 | MAP3K11 | 0.20635412 |
118 | ICK | 0.20316060 |
119 | BRAF | 0.14971674 |
120 | OXSR1 | 0.14354965 |
121 | RPS6KA1 | 0.13873147 |
122 | PRKACG | 0.12171901 |
123 | TNK2 | 0.10737506 |
124 | MAPKAPK5 | 0.09228241 |
125 | CSNK1D | 0.07937692 |
126 | RAF1 | 0.06228678 |
127 | FRK | 0.05964624 |
128 | PRKCA | 0.05871026 |
129 | MAP2K2 | 0.05184246 |
130 | MAPK8 | 0.04972175 |
131 | PRKCQ | 0.03689096 |
132 | CSNK1A1 | 0.03325928 |
133 | GSK3B | 0.03292598 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 4.37072686 |
2 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.54394823 |
3 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.04485727 |
4 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.01560194 |
5 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.96434699 |
6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.39433084 |
7 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.38856815 |
8 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.37553837 |
9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.25977013 |
10 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 2.08591695 |
11 | Alzheimers disease_Homo sapiens_hsa05010 | 1.92873927 |
12 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.83669104 |
13 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.76031776 |
14 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.70540500 |
15 | Circadian entrainment_Homo sapiens_hsa04713 | 1.70409463 |
16 | Nicotine addiction_Homo sapiens_hsa05033 | 1.70138521 |
17 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.67534011 |
18 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.65934346 |
19 | Carbon metabolism_Homo sapiens_hsa01200 | 1.62810637 |
20 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.60169517 |
21 | Insulin secretion_Homo sapiens_hsa04911 | 1.56113142 |
22 | GABAergic synapse_Homo sapiens_hsa04727 | 1.52484746 |
23 | Olfactory transduction_Homo sapiens_hsa04740 | 1.48387601 |
24 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.43855715 |
25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.41489042 |
26 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.39745923 |
27 | Morphine addiction_Homo sapiens_hsa05032 | 1.35143725 |
28 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.34668447 |
29 | Long-term potentiation_Homo sapiens_hsa04720 | 1.33263780 |
30 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.31890695 |
31 | Renin secretion_Homo sapiens_hsa04924 | 1.31297394 |
32 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.31244088 |
33 | Circadian rhythm_Homo sapiens_hsa04710 | 1.30707419 |
34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.30424962 |
35 | Huntingtons disease_Homo sapiens_hsa05016 | 1.28649607 |
36 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.21887575 |
37 | Salivary secretion_Homo sapiens_hsa04970 | 1.18275936 |
38 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.17939171 |
39 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.17117593 |
40 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.17101478 |
41 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.16371383 |
42 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.16326911 |
43 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.11531508 |
44 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.10251624 |
45 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.09207552 |
46 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.08746726 |
47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.07883624 |
48 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.03666787 |
49 | Taste transduction_Homo sapiens_hsa04742 | 1.01608067 |
50 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.01037635 |
51 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.00797736 |
52 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.95263468 |
53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.93342624 |
54 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.91082287 |
55 | Insulin resistance_Homo sapiens_hsa04931 | 0.88601247 |
56 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.87355081 |
57 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.86171636 |
58 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.85820871 |
59 | Long-term depression_Homo sapiens_hsa04730 | 0.83586021 |
60 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.83366032 |
61 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.83085277 |
62 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.82851693 |
63 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.82788938 |
64 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.82247396 |
65 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.80232884 |
66 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.76879783 |
67 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.74785576 |
68 | Gap junction_Homo sapiens_hsa04540 | 0.73369303 |
69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.66312932 |
70 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.65780572 |
71 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.65039214 |
72 | Viral myocarditis_Homo sapiens_hsa05416 | 0.64223131 |
73 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.61038062 |
74 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.60645155 |
75 | Tight junction_Homo sapiens_hsa04530 | 0.59497337 |
76 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.58706477 |
77 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.57870253 |
78 | Peroxisome_Homo sapiens_hsa04146 | 0.57683673 |
79 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.57488025 |
80 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.55904095 |
81 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.54662223 |
82 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.54279584 |
83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.54158722 |
84 | Cocaine addiction_Homo sapiens_hsa05030 | 0.53271049 |
85 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.53035857 |
86 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.52962890 |
87 | Phototransduction_Homo sapiens_hsa04744 | 0.52036019 |
88 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.50848982 |
89 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.49820529 |
90 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.46920768 |
91 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.46885250 |
92 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.45925095 |
93 | Melanogenesis_Homo sapiens_hsa04916 | 0.45567194 |
94 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.43997436 |
95 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.43825630 |
96 | Focal adhesion_Homo sapiens_hsa04510 | 0.43550103 |
97 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.42960865 |
98 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.40366931 |
99 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.39841417 |
100 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.39798297 |
101 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36834917 |
102 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.36175744 |
103 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.34984101 |
104 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.32609287 |
105 | Glioma_Homo sapiens_hsa05214 | 0.32342914 |
106 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.32162554 |
107 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.31079365 |
108 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.30772932 |
109 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.30585877 |
110 | Sulfur relay system_Homo sapiens_hsa04122 | 0.29875849 |
111 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.29180629 |
112 | Histidine metabolism_Homo sapiens_hsa00340 | 0.28994554 |
113 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.28722763 |
114 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.28623306 |
115 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.28558321 |
116 | Axon guidance_Homo sapiens_hsa04360 | 0.26441978 |
117 | Bile secretion_Homo sapiens_hsa04976 | 0.25073073 |
118 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.23724226 |
119 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.23294133 |
120 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22147554 |
121 | Purine metabolism_Homo sapiens_hsa00230 | 0.21837425 |
122 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.19303975 |
123 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.17931940 |
124 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.17300475 |