TMEM8C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1multicellular organismal movement (GO:0050879)9.67398471
2musculoskeletal movement (GO:0050881)9.67398471
3positive regulation of myotube differentiation (GO:0010831)9.46509354
4plasma membrane repair (GO:0001778)8.56062273
5response to inactivity (GO:0014854)8.52638501
6regulation of syncytium formation by plasma membrane fusion (GO:0060142)8.12689633
7striated muscle atrophy (GO:0014891)7.90908766
8actin filament-based movement (GO:0030048)7.67215876
9positive regulation of skeletal muscle tissue development (GO:0048643)7.62715221
10response to stimulus involved in regulation of muscle adaptation (GO:0014874)7.18092320
11sarcoplasmic reticulum calcium ion transport (GO:0070296)6.94503338
12muscle atrophy (GO:0014889)6.82972935
13negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.76128530
14positive regulation of myoblast differentiation (GO:0045663)6.72030473
15negative regulation of protein localization to cell surface (GO:2000009)6.47187135
16muscle cell cellular homeostasis (GO:0046716)6.35531778
17muscle fiber development (GO:0048747)6.34168993
18skeletal muscle tissue development (GO:0007519)6.26487883
19regulation of skeletal muscle contraction (GO:0014819)6.23393943
20regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)6.05977462
21positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)5.76538909
22striated muscle contraction (GO:0006941)5.61626420
23sarcomere organization (GO:0045214)5.49649972
24peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)5.46466164
25heart contraction (GO:0060047)5.40578741
26heart process (GO:0003015)5.40578741
27response to muscle activity (GO:0014850)5.36811026
28bundle of His cell to Purkinje myocyte communication (GO:0086069)5.26880343
29negative regulation of potassium ion transmembrane transport (GO:1901380)5.20206280
30muscle contraction (GO:0006936)5.09286299
31myotube differentiation (GO:0014902)4.98088147
32negative regulation of nitric-oxide synthase activity (GO:0051001)4.90420526
33neuromuscular synaptic transmission (GO:0007274)4.85013398
34regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.78168341
35cellular response to estradiol stimulus (GO:0071392)4.76843310
36regulation of skeletal muscle cell differentiation (GO:2001014)4.75331953
37negative regulation of muscle hypertrophy (GO:0014741)4.69672274
38striated muscle cell development (GO:0055002)4.65309983
39muscle system process (GO:0003012)4.61763915
40synaptic transmission, cholinergic (GO:0007271)4.60587757
41* muscle organ development (GO:0007517)4.60322450
42* myoblast fusion (GO:0007520)4.57476996
43* muscle structure development (GO:0061061)4.46456556
44mRNA transcription from RNA polymerase II promoter (GO:0042789)4.31677794
45positive regulation of striated muscle cell differentiation (GO:0051155)4.29274412
46response to lithium ion (GO:0010226)4.22139413
47striated muscle tissue development (GO:0014706)4.20187744
48striated muscle adaptation (GO:0014888)4.18080224
49muscle cell development (GO:0055001)4.17852995
50* syncytium formation by plasma membrane fusion (GO:0000768)4.15642802
51negative regulation of cell size (GO:0045792)4.14277440
52negative regulation of potassium ion transport (GO:0043267)4.12597046
53neuromuscular junction development (GO:0007528)4.10009978
54actomyosin structure organization (GO:0031032)4.08295432
55cardiac muscle tissue morphogenesis (GO:0055008)4.03212339
56regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.01047744
57regulation of myotube differentiation (GO:0010830)3.98445359
58muscle tissue morphogenesis (GO:0060415)3.96923274
59positive regulation of muscle cell differentiation (GO:0051149)3.93175331
60* syncytium formation (GO:0006949)3.83760045
61regulation of muscle contraction (GO:0006937)3.83324474
62mRNA transcription (GO:0009299)3.82355583
63negative regulation of cardiac muscle hypertrophy (GO:0010614)3.80725645
64negative regulation of cardiac muscle tissue growth (GO:0055022)3.78211999
65negative regulation of heart growth (GO:0061117)3.78211999
66regulation of muscle system process (GO:0090257)3.76013611
67regulation of myoblast differentiation (GO:0045661)3.72631272
68endodermal cell differentiation (GO:0035987)3.70963292
69muscle tissue development (GO:0060537)3.70876513
70cellular response to lithium ion (GO:0071285)3.61925439
71neuronal action potential (GO:0019228)3.59046975
72heterotypic cell-cell adhesion (GO:0034113)3.56415659
73membrane raft organization (GO:0031579)3.55307165
74regulation of p38MAPK cascade (GO:1900744)3.54738850
75embryonic camera-type eye development (GO:0031076)3.53603331
76regulation of striated muscle contraction (GO:0006942)3.53307565
77regulation of action potential (GO:0098900)3.48467283
78response to gravity (GO:0009629)3.43437475
79regulation of sarcomere organization (GO:0060297)3.42357120
80regulation of potassium ion transmembrane transporter activity (GO:1901016)3.37424962
81positive regulation of astrocyte differentiation (GO:0048711)3.36625578
82actin filament depolymerization (GO:0030042)3.35073737
83positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.30932017
84muscle adaptation (GO:0043500)3.29122160
85postsynaptic membrane organization (GO:0001941)3.26312477
86regulation of cell communication by electrical coupling (GO:0010649)3.24243764
87negative regulation of organelle assembly (GO:1902116)3.23293138
88myofibril assembly (GO:0030239)3.22396966
89face morphogenesis (GO:0060325)3.18500791
90regulation of glucose import in response to insulin stimulus (GO:2001273)3.16787927
91cardiac muscle cell development (GO:0055013)3.11765135
92response to caffeine (GO:0031000)3.08337053
93positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.07798599
94regulation of cardiac muscle cell differentiation (GO:2000725)3.05551455
95cell adhesion mediated by integrin (GO:0033627)3.05384880
96cellular response to estrogen stimulus (GO:0071391)3.03871728
97ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.03088514
98regulation of integrin-mediated signaling pathway (GO:2001044)3.02856086
99regulation of cardiac muscle contraction (GO:0055117)3.02701850
100regulation of skeletal muscle fiber development (GO:0048742)3.01049845
101negative regulation of gluconeogenesis (GO:0045721)2.99153707
102regulation of skeletal muscle tissue development (GO:0048641)2.98565501
103positive regulation of protein depolymerization (GO:1901881)2.97187822
104positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.91495008
105regulation of muscle cell differentiation (GO:0051147)2.86526341
106skeletal muscle cell differentiation (GO:0035914)2.81347961
107skeletal muscle adaptation (GO:0043501)2.80634436
108regulation of muscle adaptation (GO:0043502)2.76214776
109regulation of membrane repolarization (GO:0060306)2.76087303
110cardiac muscle contraction (GO:0060048)2.75726738
111regulation of striated muscle cell differentiation (GO:0051153)2.74746378
112cardiac myofibril assembly (GO:0055003)2.74427061
113glycoprotein catabolic process (GO:0006516)2.73932943
114negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.72944745
115embryonic retina morphogenesis in camera-type eye (GO:0060059)2.70981401
116skeletal muscle tissue regeneration (GO:0043403)2.70372696
117regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.63107376
118epithelial cell-cell adhesion (GO:0090136)2.62497061
119endochondral ossification (GO:0001958)2.61100260
120replacement ossification (GO:0036075)2.61100260
121positive regulation of muscle organ development (GO:0048636)2.60194446
122positive regulation of striated muscle tissue development (GO:0045844)2.60194446
123muscle cell differentiation (GO:0042692)2.59829285
124basement membrane organization (GO:0071711)2.59255322
125membrane tubulation (GO:0097320)2.58675368
126regulation of alkaline phosphatase activity (GO:0010692)2.58227287
127skeletal muscle fiber development (GO:0048741)12.4586958
128muscle filament sliding (GO:0030049)12.0977741
129actin-myosin filament sliding (GO:0033275)12.0977741
130skeletal muscle contraction (GO:0003009)11.7119848
131myotube cell development (GO:0014904)10.4775411
132muscle cell fate commitment (GO:0042693)10.3382545
133actin-mediated cell contraction (GO:0070252)10.0138479

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GATA1_22025678_ChIP-Seq_K562_Human6.54285554
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.31016947
3RARG_19884340_ChIP-ChIP_MEFs_Mouse3.93737603
4ESR1_20079471_ChIP-ChIP_T-47D_Human3.92188334
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.68864408
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.67192349
7ZNF652_21678463_ChIP-ChIP_ZR75-1_Human3.50682482
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.15876364
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.07817643
10* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.58708474
11THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.49973088
12ESR1_21235772_ChIP-Seq_MCF-7_Human2.48284171
13CLOCK_20551151_ChIP-Seq_293T_Human2.46781082
14ZFP281_18757296_ChIP-ChIP_E14_Mouse2.39148748
15* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.32853514
16ESR2_21235772_ChIP-Seq_MCF-7_Human2.30646185
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.21175891
18WT1_19549856_ChIP-ChIP_CCG9911_Human2.11892204
19NFE2_27457419_Chip-Seq_LIVER_Mouse2.11222604
20PCGF2_27294783_Chip-Seq_NPCs_Mouse2.09133940
21WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.05513216
22LXR_22292898_ChIP-Seq_THP-1_Human2.02916776
23CRX_20693478_ChIP-Seq_RETINA_Mouse1.89505509
24P300_27058665_Chip-Seq_ZR-75-30cells_Human1.83720210
25TBX20_22328084_ChIP-Seq_HEART_Mouse1.83267355
26TBX20_22080862_ChIP-Seq_HEART_Mouse1.83267355
27SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.83232558
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.82861202
29EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.78410646
30ELK3_25401928_ChIP-Seq_HUVEC_Human1.78287295
31MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.77200292
32* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.74953945
33RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.70508291
34SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.70468670
35SUZ12_27294783_Chip-Seq_NPCs_Mouse1.69047955
36EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.68909204
37ATF3_27146783_Chip-Seq_COLON_Human1.64607123
38MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.64105677
39STAT3_18555785_Chip-Seq_ESCs_Mouse1.63936659
40KDM2B_26808549_Chip-Seq_SUP-B15_Human1.63094307
41ZNF263_19887448_ChIP-Seq_K562_Human1.62433148
42P53_22387025_ChIP-Seq_ESCs_Mouse1.56301967
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.55830847
44PU1_27457419_Chip-Seq_LIVER_Mouse1.55584425
45KDM2B_26808549_Chip-Seq_DND41_Human1.54936107
46SMC1_22415368_ChIP-Seq_MEFs_Mouse1.54103408
47EZH2_27294783_Chip-Seq_ESCs_Mouse1.52848567
48UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.50993287
49CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.49437771
50SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.48274257
51ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.46427335
52ZFP281_27345836_Chip-Seq_ESCs_Mouse1.44075078
53ZFX_18555785_Chip-Seq_ESCs_Mouse1.42547629
54CJUN_26792858_Chip-Seq_BT549_Human1.42526874
55KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.40724924
56PPAR_26484153_Chip-Seq_NCI-H1993_Human1.39288036
57KDM2B_26808549_Chip-Seq_K562_Human1.38713674
58SMAD1_18555785_Chip-Seq_ESCs_Mouse1.37795708
59RACK7_27058665_Chip-Seq_MCF-7_Human1.37072521
60EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.36923022
61ERG_21242973_ChIP-ChIP_JURKAT_Human1.35941064
62IGF1R_20145208_ChIP-Seq_DFB_Human1.35332030
63* SOX2_18555785_Chip-Seq_ESCs_Mouse1.34138002
64SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.34133577
65TP53_22127205_ChIP-Seq_IMR90_Human1.33890328
66ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.32804689
67TP53_16413492_ChIP-PET_HCT116_Human1.30481019
68SMC3_22415368_ChIP-Seq_MEFs_Mouse1.28234514
69OCT4_18555785_Chip-Seq_ESCs_Mouse1.27319332
70EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.26526163
71RAD21_21589869_ChIP-Seq_MESCs_Mouse1.26203786
72OCT4_21477851_ChIP-Seq_ESCs_Mouse1.24737191
73EP300_21415370_ChIP-Seq_HL-1_Mouse1.24660412
74DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.22720888
75EZH2_18974828_ChIP-Seq_MESCs_Mouse1.21820326
76RNF2_18974828_ChIP-Seq_MESCs_Mouse1.21820326
77CTCF_18555785_Chip-Seq_ESCs_Mouse1.21352110
78SUZ12_27294783_Chip-Seq_ESCs_Mouse1.20947110
79CTCF_21964334_Chip-Seq_Bcells_Human1.20936289
80NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.20449801
81TP53_20018659_ChIP-ChIP_R1E_Mouse1.20191232
82MTF2_20144788_ChIP-Seq_MESCs_Mouse1.19970141
83TP53_18474530_ChIP-ChIP_U2OS_Human1.18908089
84NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.18237745
85EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.18194470
86TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16219913
87* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.15753008
88TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14837378
89KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13753474
90SRF_21415370_ChIP-Seq_HL-1_Mouse1.13674393
91PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.13501918
92TCF7_22412390_ChIP-Seq_EML_Mouse1.12117583
93E2F1_18555785_Chip-Seq_ESCs_Mouse1.12023078
94IKZF1_21737484_ChIP-ChIP_HCT116_Human1.11488107
95PCGF2_27294783_Chip-Seq_ESCs_Mouse1.10677761
96P300_18555785_Chip-Seq_ESCs_Mouse1.10453098
97CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08846682
98BRD4_25478319_ChIP-Seq_HGPS_Human1.08628876
99SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08195669
100* KLF4_18555785_Chip-Seq_ESCs_Mouse1.07893882
101CTCF_27219007_Chip-Seq_Bcells_Human1.07878901
102TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.06108675
103ESRRB_18555785_Chip-Seq_ESCs_Mouse1.05200816
104* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.02946991
105HIF1A_21447827_ChIP-Seq_MCF-7_Human1.02082528
106CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.01808004
107PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.01448042
108GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.01274851
109NANOG_18555785_Chip-Seq_ESCs_Mouse1.00922104
110GATA2_21666600_ChIP-Seq_HMVEC_Human0.98940415
111KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.97998340
112SA1_27219007_Chip-Seq_ERYTHROID_Human0.96552006
113SA1_27219007_Chip-Seq_Bcells_Human0.96213583
114STAT6_21828071_ChIP-Seq_BEAS2B_Human0.95172013
115DNAJC2_21179169_ChIP-ChIP_NT2_Human0.95169765
116SOX2_20726797_ChIP-Seq_SW620_Human0.95107690
117FOXH1_21741376_ChIP-Seq_ESCs_Human0.95047035
118NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.94742633
119NRF2_20460467_ChIP-Seq_MEFs_Mouse0.94742633
120TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94634374
121CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94219437
122NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.93757259
123ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93273943
124SA1_22415368_ChIP-Seq_MEFs_Mouse0.92716344
125NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92550021
126CDX2_19796622_ChIP-Seq_MESCs_Mouse0.92089485
127KDM2B_26808549_Chip-Seq_JURKAT_Human0.91796513
128CTCF_27219007_Chip-Seq_ERYTHROID_Human0.91662069
129NMYC_18555785_Chip-Seq_ESCs_Mouse0.91607911
130KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.91355913
131GATA1_19941826_ChIP-Seq_K562_Human0.90689311
132BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.90630328
133TP53_23651856_ChIP-Seq_MEFs_Mouse0.90278311
134CBP_20019798_ChIP-Seq_JUKART_Human0.90140019
135IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.90140019
136TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.89697221
137CMYC_18555785_Chip-Seq_ESCs_Mouse0.88489128
138CTCF_26484167_Chip-Seq_Bcells_Mouse0.88317591
139SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.87309425
140GATA1_26923725_Chip-Seq_HPCs_Mouse0.87062515
141ELK1_22589737_ChIP-Seq_MCF10A_Human0.86562159
142UBF1/2_26484160_Chip-Seq_HMECs_Human0.86468794
143CTCF_21964334_ChIP-Seq_BJAB-B_Human0.85707509
144CREB1_26743006_Chip-Seq_LNCaP_Human0.85695008
145PPARA_22158963_ChIP-Seq_LIVER_Mouse0.85172238
146SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.84545002
147EOMES_21245162_ChIP-Seq_HESCs_Human0.82182207
148PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.80923633
149MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.80756811
150OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.80724111
151SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.79255479
152STAT3_1855785_ChIP-Seq_MESCs_Mouse0.78719325
153SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.78578076

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000749_muscle_degeneration6.70792388
2MP0000751_myopathy6.43919543
3MP0000733_abnormal_muscle_development5.30026685
4MP0004270_analgesia4.89421798
5MP0000750_abnormal_muscle_regeneration4.78235324
6MP0004145_abnormal_muscle_electrophysio4.36227500
7MP0000747_muscle_weakness4.35567298
8MP0002106_abnormal_muscle_physiology3.96513309
9MP0000759_abnormal_skeletal_muscle3.72199366
10MP0004087_abnormal_muscle_fiber3.52110423
11MP0005369_muscle_phenotype3.27889104
12MP0002837_dystrophic_cardiac_calcinosis3.23655974
13MP0002269_muscular_atrophy3.05659247
14MP0008438_abnormal_cutaneous_collagen2.54500902
15MP0001542_abnormal_bone_strength2.51233055
16MP0004233_abnormal_muscle_weight2.39996900
17MP0002108_abnormal_muscle_morphology2.34502967
18MP0004084_abnormal_cardiac_muscle2.23019107
19MP0002971_abnormal_brown_adipose2.14626263
20MP0005623_abnormal_meninges_morphology2.13769436
21MP0003950_abnormal_plasma_membrane1.90572435
22MP0002249_abnormal_larynx_morphology1.88895513
23MP0009780_abnormal_chondrocyte_physiolo1.87679966
24MP0004036_abnormal_muscle_relaxation1.76291193
25MP0005330_cardiomyopathy1.64837927
26MP0005620_abnormal_muscle_contractility1.62539451
27MP0010030_abnormal_orbit_morphology1.58340010
28MP0005503_abnormal_tendon_morphology1.50498419
29MP0004858_abnormal_nervous_system1.46647314
30MP0002736_abnormal_nociception_after1.46450738
31MP0002734_abnormal_mechanical_nocicepti1.46187593
32MP0003011_delayed_dark_adaptation1.44958418
33MP0001299_abnormal_eye_distance/1.44780988
34MP0003941_abnormal_skin_development1.39891281
35MP0004215_abnormal_myocardial_fiber1.34761572
36MP0005275_abnormal_skin_tensile1.28875440
37MP0010630_abnormal_cardiac_muscle1.22719243
38MP0004883_abnormal_blood_vessel1.20885440
39MP0003279_aneurysm1.19175755
40MP0003566_abnormal_cell_adhesion1.17805891
41MP0000767_abnormal_smooth_muscle1.17335336
42MP0003705_abnormal_hypodermis_morpholog1.12033652
43MP0003091_abnormal_cell_migration1.02644486
44MP0002972_abnormal_cardiac_muscle1.02604879
45MP0002822_catalepsy1.01491153
46MP0008775_abnormal_heart_ventricle0.99986454
47MP0002877_abnormal_melanocyte_morpholog0.97631233
48MP0003879_abnormal_hair_cell0.96572019
49MP0002234_abnormal_pharynx_morphology0.96152402
50MP0003385_abnormal_body_wall0.93399669
51MP0002114_abnormal_axial_skeleton0.92328447
52MP0009250_abnormal_appendicular_skeleto0.88861876
53MP0004272_abnormal_basement_membrane0.85247437
54MP0002184_abnormal_innervation0.81388666
55MP0001915_intracranial_hemorrhage0.79622031
56MP0005165_increased_susceptibility_to0.77203166
57MP0001440_abnormal_grooming_behavior0.75427892
58MP0005508_abnormal_skeleton_morphology0.74055710
59MP0002127_abnormal_cardiovascular_syste0.74050785
60MP0003115_abnormal_respiratory_system0.72623143
61MP0001943_abnormal_respiration0.72219898
62MP0000013_abnormal_adipose_tissue0.71746674
63MP0005248_abnormal_Harderian_gland0.70651989
64MP0001346_abnormal_lacrimal_gland0.70637248
65MP0001968_abnormal_touch/_nociception0.69039531
66MP0003806_abnormal_nucleotide_metabolis0.65872895
67MP0003221_abnormal_cardiomyocyte_apopto0.65309007
68MP0001661_extended_life_span0.64003274
69MP0004484_altered_response_of0.61127326
70MP0005171_absent_coat_pigmentation0.60609339
71MP0003948_abnormal_gas_homeostasis0.60600656
72MP0008569_lethality_at_weaning0.60248609
73MP0002295_abnormal_pulmonary_circulatio0.60214937
74MP0004510_myositis0.59819937
75MP0003137_abnormal_impulse_conducting0.58450431
76MP0004134_abnormal_chest_morphology0.58264509
77MP0002932_abnormal_joint_morphology0.57300871
78MP0001986_abnormal_taste_sensitivity0.57248365
79MP0005367_renal/urinary_system_phenotyp0.57078755
80MP0000516_abnormal_urinary_system0.57078755
81MP0006138_congestive_heart_failure0.56550991
82MP0000858_altered_metastatic_potential0.56411075
83MP0003755_abnormal_palate_morphology0.56189731
84MP0003300_gastrointestinal_ulcer0.55984043
85MP0003942_abnormal_urinary_system0.55855372
86MP0002896_abnormal_bone_mineralization0.55522059
87MP0000955_abnormal_spinal_cord0.55459696
88MP0004130_abnormal_muscle_cell0.54311159
89MP0005164_abnormal_response_to0.53775327
90MP0004197_abnormal_fetal_growth/weight/0.53582736
91MP0000003_abnormal_adipose_tissue0.53135625
92MP0002132_abnormal_respiratory_system0.52018768
93MP0005023_abnormal_wound_healing0.49881596
94MP0002089_abnormal_postnatal_growth/wei0.48663504
95MP0000428_abnormal_craniofacial_morphol0.48168984
96MP0000678_abnormal_parathyroid_gland0.47967266
97MP0005076_abnormal_cell_differentiation0.45458807
98MP0002133_abnormal_respiratory_system0.45312194
99MP0005388_respiratory_system_phenotype0.45312194
100MP0002081_perinatal_lethality0.45130804
101MP0005595_abnormal_vascular_smooth0.44612182
102MP0000762_abnormal_tongue_morphology0.44156909
103MP0008789_abnormal_olfactory_epithelium0.43724769
104MP0005058_abnormal_lysosome_morphology0.43243649
105MP0006054_spinal_hemorrhage0.43143326
106MP0002128_abnormal_blood_circulation0.42836905
107MP0002933_joint_inflammation0.42338544
108MP0009384_cardiac_valve_regurgitation0.41320503
109MP0005266_abnormal_metabolism0.40555413
110MP0003828_pulmonary_edema0.40226899
111MP0003959_abnormal_lean_body0.40087205
112MP0002332_abnormal_exercise_endurance0.39694159
113MP0001958_emphysema0.39577785
114MP0005193_abnormal_anterior_eye0.39385788
115MP0005319_abnormal_enzyme/_coenzyme0.38930606
116MP0001243_abnormal_dermal_layer0.38373649
117MP0005452_abnormal_adipose_tissue0.38200162
118MP0001544_abnormal_cardiovascular_syste0.37629858
119MP0005385_cardiovascular_system_phenoty0.37629858
120MP0000266_abnormal_heart_morphology0.36671953
121MP0004085_abnormal_heartbeat0.35396931
122MP0001784_abnormal_fluid_regulation0.35315817
123MP0002060_abnormal_skin_morphology0.34987083
124MP0002163_abnormal_gland_morphology0.34583768
125MP0005621_abnormal_cell_physiology0.33975843
126MP0001756_abnormal_urination0.33727739
127MP0000163_abnormal_cartilage_morphology0.33501607
128MP0000249_abnormal_blood_vessel0.33250844
129MP0003283_abnormal_digestive_organ0.32586316
130MP0001175_abnormal_lung_morphology0.30453897

Predicted human phenotypes

RankGene SetZ-score
1Fetal akinesia sequence (HP:0001989)9.30775904
2Popliteal pterygium (HP:0009756)9.07618452
3Aplasia of the musculature (HP:0100854)8.20563547
4Amniotic constriction ring (HP:0009775)7.95402642
5Abnormality of placental membranes (HP:0011409)7.95402642
6Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)7.16698354
7Nemaline bodies (HP:0003798)6.89027726
8Akinesia (HP:0002304)6.77405354
9Muscle fiber inclusion bodies (HP:0100299)6.59774247
10Malignant hyperthermia (HP:0002047)6.58001371
11Type 1 muscle fiber predominance (HP:0003803)6.36047676
12Distal arthrogryposis (HP:0005684)5.91131924
13Type 2 muscle fiber atrophy (HP:0003554)5.75604901
14Round ear (HP:0100830)5.62857983
15Ulnar deviation of the wrist (HP:0003049)5.35838357
16Muscle fiber atrophy (HP:0100295)5.22897787
17Abnormality of the neuromuscular junction (HP:0003398)5.00942421
18Fatigable weakness (HP:0003473)5.00942421
19Weak cry (HP:0001612)4.94905965
20Aplasia/Hypoplasia involving the musculature (HP:0001460)4.90145617
21Pterygium (HP:0001059)4.70524060
22Calcaneovalgus deformity (HP:0001848)4.65203462
23Thin ribs (HP:0000883)4.64416315
24Myopathic facies (HP:0002058)4.42486552
25Hypoplastic heart (HP:0001961)4.30746329
26Deformed tarsal bones (HP:0008119)4.19687697
27Bulbar palsy (HP:0001283)4.19491657
28Gowers sign (HP:0003391)4.01984096
29Absent phalangeal crease (HP:0006109)3.96142909
30Sudden death (HP:0001699)3.89204914
31Abnormality of skeletal muscle fiber size (HP:0012084)3.77497340
32Cystic hygroma (HP:0000476)3.74135482
33Long clavicles (HP:0000890)3.61531827
34Mildly elevated creatine phosphokinase (HP:0008180)3.51663374
35Easy fatigability (HP:0003388)3.50233740
36Diminished movement (HP:0002374)3.36992078
37Difficulty climbing stairs (HP:0003551)3.36864527
38Abnormal finger flexion creases (HP:0006143)3.30722517
39Hip contracture (HP:0003273)3.28195420
40Muscle fiber splitting (HP:0003555)3.24976817
41Difficulty running (HP:0009046)3.23648139
42EMG: myopathic abnormalities (HP:0003458)3.17282919
43Trismus (HP:0000211)3.16123591
44Abnormality of the calf musculature (HP:0001430)3.10945805
45Abnormalities of placenta or umbilical cord (HP:0001194)3.09393023
46Slender build (HP:0001533)3.08097195
47Centrally nucleated skeletal muscle fibers (HP:0003687)3.06205846
48Distal lower limb muscle weakness (HP:0009053)3.00452620
49Neonatal respiratory distress (HP:0002643)2.98888978
50Generalized muscle weakness (HP:0003324)2.96809143
51Increased variability in muscle fiber diameter (HP:0003557)2.95170013
52Abnormality of the calcaneus (HP:0008364)2.91374788
53Breech presentation (HP:0001623)2.78935640
54Depressed nasal tip (HP:0000437)2.77713524
55Asymmetric septal hypertrophy (HP:0001670)2.69538168
56Hyporeflexia of lower limbs (HP:0002600)2.64439608
57Symphalangism affecting the phalanges of the hand (HP:0009773)2.60983292
58Calf muscle hypertrophy (HP:0008981)2.59268408
59Poor suck (HP:0002033)2.53868408
60Increased connective tissue (HP:0009025)2.51854115
61Chin dimple (HP:0010751)2.51205077
62Webbed neck (HP:0000465)2.51172241
63Neck muscle weakness (HP:0000467)2.50485611
64Respiratory insufficiency due to muscle weakness (HP:0002747)2.46840436
65Arthrogryposis multiplex congenita (HP:0002804)2.38059849
66Distal lower limb amyotrophy (HP:0008944)2.34019475
67Abnormality of the left ventricular outflow tract (HP:0011103)2.32328094
68Subaortic stenosis (HP:0001682)2.32328094
69Muscle hypertrophy of the lower extremities (HP:0008968)2.30388901
70Decreased muscle mass (HP:0003199)2.30265584
71Limited hip movement (HP:0008800)2.29306221
72Frequent falls (HP:0002359)2.27613898
73Spinal rigidity (HP:0003306)2.27035923
74Scapular winging (HP:0003691)2.25225562
75Areflexia of lower limbs (HP:0002522)2.23976201
76Mask-like facies (HP:0000298)2.21176415
77Rib fusion (HP:0000902)2.17033263
78Vertebral fusion (HP:0002948)2.16079299
79Exercise-induced myalgia (HP:0003738)2.09514363
80Fused cervical vertebrae (HP:0002949)2.09441095
81Metatarsus adductus (HP:0001840)2.08298515
82Hypoplastic nipples (HP:0002557)2.04579819
83Infantile muscular hypotonia (HP:0008947)1.95401263
84EMG: neuropathic changes (HP:0003445)1.92964554
85Abnormality of the labia majora (HP:0012881)1.88269166
86Protrusio acetabuli (HP:0003179)1.86753670
87Joint contractures involving the joints of the feet (HP:0100492)1.86641016
88Flexion contracture of toe (HP:0005830)1.86641016
89Vertebral clefting (HP:0008428)1.85568852
90Myotonia (HP:0002486)1.83881587
91Limb-girdle muscle atrophy (HP:0003797)1.83772320
92Lower limb amyotrophy (HP:0007210)1.82851755
93Generalized amyotrophy (HP:0003700)1.79267673
94Abnormality of the umbilical cord (HP:0010881)1.78691320
95Knee flexion contracture (HP:0006380)1.73861405
96Premature rupture of membranes (HP:0001788)1.69956730
97Lipoatrophy (HP:0100578)1.68428728
98Bundle branch block (HP:0011710)1.67603367
99Facial diplegia (HP:0001349)1.67212418
100Waddling gait (HP:0002515)1.64610819
101Abnormal auditory evoked potentials (HP:0006958)1.64486385
102Aortic aneurysm (HP:0004942)1.63149368
103Rocker bottom foot (HP:0001838)1.61962823
104Limb-girdle muscle weakness (HP:0003325)1.61298962
105Nonprogressive disorder (HP:0003680)1.61268687
106Short thorax (HP:0010306)1.60970577
107Upper limb amyotrophy (HP:0009129)1.60934660
108Distal upper limb amyotrophy (HP:0007149)1.60934660
109Short palpebral fissure (HP:0012745)1.59943972
110Exostoses (HP:0100777)1.58600529
111Pulmonary hypoplasia (HP:0002089)1.57455819
112Left ventricular hypertrophy (HP:0001712)1.54477233
113Tarsal synostosis (HP:0008368)1.54159833
114Abnormality of the shoulder girdle musculature (HP:0001435)1.53376604
115Right ventricular cardiomyopathy (HP:0011663)1.53369927
116Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.52024457
117Muscle stiffness (HP:0003552)1.51397493
118Exercise-induced muscle cramps (HP:0003710)1.50774901
119Congenital hip dislocation (HP:0001374)1.50746106
120Dislocated radial head (HP:0003083)1.49182751
121Ulnar deviation of finger (HP:0009465)1.45758317
122Aortic dissection (HP:0002647)1.44605605
123Hypoplastic ischia (HP:0003175)1.42513993
124Congenital diaphragmatic hernia (HP:0000776)1.42113317
125Absent septum pellucidum (HP:0001331)1.41029101
126Delayed gross motor development (HP:0002194)1.34889816
127Slender long bone (HP:0003100)1.32280461
128Stillbirth (HP:0003826)1.25442846

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIK3CG7.17860607
2MUSK6.80930659
3MOS6.37232476
4TRIB35.06146556
5PIM23.73084734
6CCNB12.22145601
7MAP3K102.20435965
8MAP2K12.04470260
9PKN21.96642691
10PAK41.91655339
11OBSCN1.87563489
12ARAF1.87554867
13CDK61.74574094
14CDK141.66552460
15ILK1.64319968
16EEF2K1.63860146
17PLK21.59546562
18CDK151.59482096
19EPHB11.57123775
20CDK181.52715550
21MAP3K131.51197441
22CDK11A1.47541470
23TTN1.47206134
24MYLK1.46008504
25PBK1.41994176
26MAPKAPK31.41348642
27DYRK1B1.33590058
28ROCK21.32617226
29ICK1.30819940
30STK161.27546651
31DDR21.25711120
32MAP3K91.22038026
33STK391.19764410
34TESK11.19659015
35MAPK121.18381847
36AKT21.15375787
37MAP3K121.11007312
38MARK11.05869104
39RIPK11.03475774
40PTK61.00290253
41DAPK30.98319203
42CSNK1G20.93349794
43PDGFRA0.93180498
44TRPM70.92966297
45ROCK10.88445887
46LRRK20.87848569
47MAP3K50.87722733
48SIK10.86509454
49PRKG20.86210777
50MTOR0.85015197
51PTK20.80454881
52LIMK10.79655952
53MARK20.75992568
54BCKDK0.72776103
55FLT30.70992688
56LATS20.69983271
57FGFR40.69093964
58CAMK2D0.64539339
59NEK90.62225791
60EPHB20.62201075
61ERN10.58849007
62MAP3K70.58097038
63PTK2B0.56334850
64FER0.55507126
65CDK190.55301351
66PINK10.53909817
67NEK10.53147342
68RPS6KA30.51569989
69MELK0.51340145
70CDK50.49750522
71PRKG10.48128513
72PDK20.46934260
73PHKG20.46909724
74PHKG10.46909724
75TYRO30.45472229
76DMPK0.45461327
77NTRK20.42762716
78DAPK20.42256669
79MAPK70.39571466
80BMX0.39294303
81CAMK2A0.39120857
82ALK0.38716895
83MAPK110.38606019
84CDC42BPA0.36855028
85PAK60.36454020
86ABL10.36197548
87PAK30.36107742
88CAMK2G0.35112380
89PDPK10.33777217
90PAK20.32213773
91SCYL20.31892892
92MAPK100.31306471
93CDK120.30805073
94RET0.30342210
95EGFR0.28906227
96CSNK1D0.28607896
97FGFR10.28108381
98CAMKK10.28106626
99KSR20.27718028
100PRKCG0.26675761
101KSR10.26355989
102CSNK1G30.26265167
103EPHA30.26122052
104RAF10.25924966
105WNK40.24861109
106PNCK0.24783648
107CAMK2B0.24366313
108OXSR10.23729014
109PRKD30.23663081
110PDGFRB0.23485861
111PAK10.23368988
112MAPKAPK20.23264762
113BRAF0.22661695
114PRKACB0.22132746
115INSR0.21735547
116PDK30.21591655
117PDK40.21591655
118VRK20.21417770
119PIK3CA0.21349501
120TGFBR20.20993365
121RPS6KB20.20372635
122CDK90.20155343
123MAPK40.19849926
124CDK80.19830377
125MAPK90.19413669
126PRKD10.19371548
127CSNK1A1L0.18818535
128NTRK10.18348601
129LATS10.17552397
130MAPK80.16546331
131SRC0.16393778
132PRKCA0.16238376
133CSNK2A20.15986462
134IGF1R0.15962823
135ABL20.15405458
136PRKD20.14735284
137PLK30.13387014
138MAP2K30.13267751
139PDK10.13169868
140CSNK1G10.12797119
141ERBB30.12706716
142CSNK1E0.12505700
143HIPK20.11651042
144CSNK2A10.11498916

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054105.71901801
2Dilated cardiomyopathy_Homo sapiens_hsa054145.55786934
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054125.48410476
4Cardiac muscle contraction_Homo sapiens_hsa042602.93770428
5Focal adhesion_Homo sapiens_hsa045102.50191364
6Tight junction_Homo sapiens_hsa045302.45419853
7ECM-receptor interaction_Homo sapiens_hsa045122.29197862
8Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.04618996
9Proteoglycans in cancer_Homo sapiens_hsa052051.98427369
10Viral myocarditis_Homo sapiens_hsa054161.90266777
11Circadian rhythm_Homo sapiens_hsa047101.82336935
12Oxytocin signaling pathway_Homo sapiens_hsa049211.81859911
13Proteasome_Homo sapiens_hsa030501.63067291
14Cyanoamino acid metabolism_Homo sapiens_hsa004601.61596244
15Bladder cancer_Homo sapiens_hsa052191.60882021
16Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.40912946
17Chronic myeloid leukemia_Homo sapiens_hsa052201.40168268
18Amoebiasis_Homo sapiens_hsa051461.38270132
19Regulation of actin cytoskeleton_Homo sapiens_hsa048101.32819780
20Leukocyte transendothelial migration_Homo sapiens_hsa046701.27839433
21Adherens junction_Homo sapiens_hsa045201.24540450
22Insulin signaling pathway_Homo sapiens_hsa049101.18974896
23Glioma_Homo sapiens_hsa052141.12937551
24Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12163804
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.06951611
26Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04894699
27Alzheimers disease_Homo sapiens_hsa050101.04263854
28MAPK signaling pathway_Homo sapiens_hsa040101.02582064
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.01598765
30Prion diseases_Homo sapiens_hsa050201.01537461
31Glucagon signaling pathway_Homo sapiens_hsa049221.00149834
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.99792713
33Parkinsons disease_Homo sapiens_hsa050120.99264411
34Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.97643956
35Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.94436724
36Central carbon metabolism in cancer_Homo sapiens_hsa052300.93520041
37SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92776507
38HIF-1 signaling pathway_Homo sapiens_hsa040660.91775693
39Vascular smooth muscle contraction_Homo sapiens_hsa042700.91308100
40Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90267632
41Oxidative phosphorylation_Homo sapiens_hsa001900.87693769
42Melanoma_Homo sapiens_hsa052180.86735235
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.86729686
44Protein digestion and absorption_Homo sapiens_hsa049740.85853758
45Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.85674374
46Protein export_Homo sapiens_hsa030600.85060134
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82225967
48Folate biosynthesis_Homo sapiens_hsa007900.82062328
49Renal cell carcinoma_Homo sapiens_hsa052110.80262354
50Arginine and proline metabolism_Homo sapiens_hsa003300.79641954
51Salmonella infection_Homo sapiens_hsa051320.78380915
52GnRH signaling pathway_Homo sapiens_hsa049120.78033676
53Axon guidance_Homo sapiens_hsa043600.77326712
54Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.76971717
55Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76864121
56Fatty acid elongation_Homo sapiens_hsa000620.74824454
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72579074
58Hippo signaling pathway_Homo sapiens_hsa043900.72559187
59Melanogenesis_Homo sapiens_hsa049160.72417933
60Prostate cancer_Homo sapiens_hsa052150.72387338
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.71909889
62FoxO signaling pathway_Homo sapiens_hsa040680.71508398
63Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71095727
64Starch and sucrose metabolism_Homo sapiens_hsa005000.70674101
65Cholinergic synapse_Homo sapiens_hsa047250.70572093
66Estrogen signaling pathway_Homo sapiens_hsa049150.69129850
67Platelet activation_Homo sapiens_hsa046110.68311122
68Insulin secretion_Homo sapiens_hsa049110.67966215
69VEGF signaling pathway_Homo sapiens_hsa043700.67696042
70Pyruvate metabolism_Homo sapiens_hsa006200.67494975
71Gap junction_Homo sapiens_hsa045400.67211479
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67161638
73mTOR signaling pathway_Homo sapiens_hsa041500.66550600
74Adipocytokine signaling pathway_Homo sapiens_hsa049200.66478203
75Insulin resistance_Homo sapiens_hsa049310.66131166
76ErbB signaling pathway_Homo sapiens_hsa040120.64983902
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64832299
78PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63784055
79Biosynthesis of amino acids_Homo sapiens_hsa012300.63396005
80AMPK signaling pathway_Homo sapiens_hsa041520.62409615
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60736068
82Ribosome_Homo sapiens_hsa030100.60290331
83Renin secretion_Homo sapiens_hsa049240.59851136
84Pancreatic cancer_Homo sapiens_hsa052120.58949651
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.58843816
86Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.56172509
87Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55993370
88Calcium signaling pathway_Homo sapiens_hsa040200.55019819
89Sulfur relay system_Homo sapiens_hsa041220.54591482
90Basal cell carcinoma_Homo sapiens_hsa052170.53176764
91TGF-beta signaling pathway_Homo sapiens_hsa043500.52929069
92Selenocompound metabolism_Homo sapiens_hsa004500.51327253
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49601131
94Huntingtons disease_Homo sapiens_hsa050160.49479100
95Endocytosis_Homo sapiens_hsa041440.49246694
96Hedgehog signaling pathway_Homo sapiens_hsa043400.48812120
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48785836
98Nitrogen metabolism_Homo sapiens_hsa009100.47142910
99MicroRNAs in cancer_Homo sapiens_hsa052060.45663376
100Acute myeloid leukemia_Homo sapiens_hsa052210.45412642
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45340729
102Glutathione metabolism_Homo sapiens_hsa004800.45056314
103Salivary secretion_Homo sapiens_hsa049700.45036086
104Sulfur metabolism_Homo sapiens_hsa009200.44832422
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.43839914
106Endometrial cancer_Homo sapiens_hsa052130.43605834
107p53 signaling pathway_Homo sapiens_hsa041150.43573466
108Non-small cell lung cancer_Homo sapiens_hsa052230.42231614
109Long-term depression_Homo sapiens_hsa047300.40727336
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.39793652
111Carbon metabolism_Homo sapiens_hsa012000.39284081
112Cocaine addiction_Homo sapiens_hsa050300.38324219
113Wnt signaling pathway_Homo sapiens_hsa043100.37945887
114Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37917998
115Notch signaling pathway_Homo sapiens_hsa043300.37858936
116Circadian entrainment_Homo sapiens_hsa047130.37279964
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36033672
118Malaria_Homo sapiens_hsa051440.35987197
119Dorso-ventral axis formation_Homo sapiens_hsa043200.35848192
120Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.35046696
121Gastric acid secretion_Homo sapiens_hsa049710.34945654
122B cell receptor signaling pathway_Homo sapiens_hsa046620.33876905
123Small cell lung cancer_Homo sapiens_hsa052220.33148236
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32843901
125Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.31574350
126HTLV-I infection_Homo sapiens_hsa051660.31168206
127Bile secretion_Homo sapiens_hsa049760.30972540
128Phospholipase D signaling pathway_Homo sapiens_hsa040720.30618452
129Pathways in cancer_Homo sapiens_hsa052000.30523381
130Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30320100
131Basal transcription factors_Homo sapiens_hsa030220.28274339
132Thyroid hormone synthesis_Homo sapiens_hsa049180.25576523
133Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25472325
134Vibrio cholerae infection_Homo sapiens_hsa051100.25261652
135Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.24311260
136One carbon pool by folate_Homo sapiens_hsa006700.21215369
137Propanoate metabolism_Homo sapiens_hsa006400.19143073
138Collecting duct acid secretion_Homo sapiens_hsa049660.17862489
139RNA polymerase_Homo sapiens_hsa030200.15411626
140RNA degradation_Homo sapiens_hsa030180.15248689
141Pertussis_Homo sapiens_hsa051330.12973671

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