TMEM94

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)5.51555316
2cardiac myofibril assembly (GO:0055003)5.29987926
3negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.00081389
4carnitine shuttle (GO:0006853)4.86687262
5negative regulation of potassium ion transmembrane transport (GO:1901380)4.81337538
6myofibril assembly (GO:0030239)4.54295321
7cardiac muscle contraction (GO:0060048)4.42388719
8fatty acid transmembrane transport (GO:1902001)4.37301157
9tricarboxylic acid cycle (GO:0006099)4.33269136
10plasma membrane repair (GO:0001778)4.30711806
11lysine metabolic process (GO:0006553)4.24853791
12lysine catabolic process (GO:0006554)4.24853791
13negative regulation of erythrocyte differentiation (GO:0045647)4.22912288
14regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.10006515
15cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.09787234
16semaphorin-plexin signaling pathway (GO:0071526)4.08458863
17ventricular cardiac muscle cell action potential (GO:0086005)4.06089483
182-oxoglutarate metabolic process (GO:0006103)3.92632075
19cell communication involved in cardiac conduction (GO:0086065)3.91281386
20bundle of His cell to Purkinje myocyte communication (GO:0086069)3.89828672
21positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.89564201
22carnitine transmembrane transport (GO:1902603)3.86330343
23regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.84731139
24cell communication by electrical coupling (GO:0010644)3.77287136
25carnitine transport (GO:0015879)3.75673588
26amino-acid betaine transport (GO:0015838)3.75673588
27cardiac muscle cell development (GO:0055013)3.75659182
28synaptic vesicle docking involved in exocytosis (GO:0016081)3.75287455
29regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.72992916
30actomyosin structure organization (GO:0031032)3.70668865
31aspartate family amino acid catabolic process (GO:0009068)3.70306937
32muscle filament sliding (GO:0030049)3.69765971
33actin-myosin filament sliding (GO:0033275)3.69765971
34mannose metabolic process (GO:0006013)3.68322650
35adult heart development (GO:0007512)3.62476298
36regulation of actin filament-based movement (GO:1903115)3.61895201
37regulation of extracellular matrix disassembly (GO:0010715)3.61094106
38cardiac cell development (GO:0055006)3.58669528
39regulation of female receptivity (GO:0045924)3.53769676
40heart trabecula formation (GO:0060347)3.52099121
41lung epithelium development (GO:0060428)3.46877638
42regulation of fatty acid oxidation (GO:0046320)3.44581321
43regulation of ARF GTPase activity (GO:0032312)3.44164489
44cell-cell junction maintenance (GO:0045217)3.39727013
45regulation of skeletal muscle contraction (GO:0014819)3.39696875
46regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.39407958
47peptidyl-tyrosine autophosphorylation (GO:0038083)3.37053068
48striated muscle contraction (GO:0006941)3.36745945
49proline metabolic process (GO:0006560)3.36263351
50planar cell polarity pathway involved in neural tube closure (GO:0090179)3.31257514
51regulation of cholesterol biosynthetic process (GO:0045540)3.26100211
52cardiac muscle hypertrophy (GO:0003300)3.25836415
53tricarboxylic acid metabolic process (GO:0072350)3.24653029
54regulation of membrane repolarization (GO:0060306)3.24292233
55fatty acid beta-oxidation (GO:0006635)3.23578614
56positive regulation of fatty acid beta-oxidation (GO:0032000)3.21634855
57regulation of ARF protein signal transduction (GO:0032012)3.20344892
58alpha-linolenic acid metabolic process (GO:0036109)3.18412108
59negative regulation of cell size (GO:0045792)3.17492418
60negative regulation of cytosolic calcium ion concentration (GO:0051481)3.14370894
61regulation of fatty acid beta-oxidation (GO:0031998)3.13925290
62protein retention in ER lumen (GO:0006621)3.13133095
63regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.10056476
64regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.09594982
65striated muscle hypertrophy (GO:0014897)3.09392045
66adherens junction assembly (GO:0034333)3.09276773
67cardiac muscle tissue morphogenesis (GO:0055008)3.08865137
68female mating behavior (GO:0060180)3.08632412
69regulation of the force of heart contraction (GO:0002026)3.05879903
70quaternary ammonium group transport (GO:0015697)3.04469422
71positive regulation of synapse maturation (GO:0090129)3.04078955
72ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.03187164
73fatty acid homeostasis (GO:0055089)3.02932332
74regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.99498606
75actin-mediated cell contraction (GO:0070252)2.97812534
76stress granule assembly (GO:0034063)2.96509582
77NADH metabolic process (GO:0006734)2.94420434
78positive regulation of fatty acid oxidation (GO:0046321)2.93704368
79dicarboxylic acid biosynthetic process (GO:0043650)2.92924631
80focal adhesion assembly (GO:0048041)2.92848745
81cell-substrate adherens junction assembly (GO:0007045)2.92848745
82cardiac muscle cell action potential involved in contraction (GO:0086002)2.92188045
83retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.90560840
84positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.88098994
85COPI coating of Golgi vesicle (GO:0048205)2.87172703
86Golgi transport vesicle coating (GO:0048200)2.87172703
87cardiac muscle cell action potential (GO:0086001)2.86928722
88regulation of extracellular matrix organization (GO:1903053)2.86063647
89maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.85888203
90cardiac conduction (GO:0061337)2.84745637
91regulation of striated muscle contraction (GO:0006942)2.84724740
92membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.83842788
93fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.83757919
94short-chain fatty acid metabolic process (GO:0046459)2.83020342
95creatine metabolic process (GO:0006600)2.79594191
96fatty acid oxidation (GO:0019395)2.79250854
97regulation of cholesterol homeostasis (GO:2000188)2.78583435
98regulation of heart rate by cardiac conduction (GO:0086091)2.78506484
99cytoskeletal anchoring at plasma membrane (GO:0007016)2.75868957
100muscle tissue morphogenesis (GO:0060415)2.75845050
101positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.75512230
102proline biosynthetic process (GO:0006561)2.74393689
103potassium ion import (GO:0010107)2.73383719
104lipid oxidation (GO:0034440)2.73263091
105glyoxylate metabolic process (GO:0046487)2.72237077
106negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.71395864
107regulation of cholesterol metabolic process (GO:0090181)2.70965659
108fatty acid catabolic process (GO:0009062)2.70317646
109cell volume homeostasis (GO:0006884)2.70258810
110biotin metabolic process (GO:0006768)2.69821756
111basement membrane organization (GO:0071711)2.69800434
112sodium ion export (GO:0071436)2.69244638
113insulin-like growth factor receptor signaling pathway (GO:0048009)2.68741762
114positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.67806699
115regulation of acyl-CoA biosynthetic process (GO:0050812)2.67776436
116glycogen catabolic process (GO:0005980)2.67540823
117cell migration in hindbrain (GO:0021535)2.67433746
118sarcoplasmic reticulum calcium ion transport (GO:0070296)2.67066601
119cellular ketone body metabolic process (GO:0046950)2.66498928
120acetyl-CoA metabolic process (GO:0006084)2.66138774
121apoptotic process involved in morphogenesis (GO:0060561)2.63425045
122regulation of heart rate (GO:0002027)2.63274985
123actin filament-based movement (GO:0030048)2.62510021
124cerebellar granule cell differentiation (GO:0021707)2.62341589
125oxaloacetate metabolic process (GO:0006107)2.62301652
126negative regulation of potassium ion transport (GO:0043267)2.62207073
127muscle hypertrophy (GO:0014896)2.61590687
128glucan catabolic process (GO:0009251)2.61359864
129histone H4 deacetylation (GO:0070933)2.60318216
130epithelial cell differentiation involved in prostate gland development (GO:0060742)2.60095509
131relaxation of cardiac muscle (GO:0055119)2.59954844
132negative regulation of cholesterol transport (GO:0032375)2.59954143
133negative regulation of sterol transport (GO:0032372)2.59954143
134layer formation in cerebral cortex (GO:0021819)2.59480203
135cardiac muscle adaptation (GO:0014887)2.59424193
136cardiac muscle hypertrophy in response to stress (GO:0014898)2.59424193
137muscle hypertrophy in response to stress (GO:0003299)2.59424193
138cell junction maintenance (GO:0034331)2.58731131
139cardiac muscle cell proliferation (GO:0060038)2.58545249
140negative regulation of heart growth (GO:0061117)2.57545864
141negative regulation of cardiac muscle tissue growth (GO:0055022)2.57545864
142regulation of cardiac muscle cell contraction (GO:0086004)2.57440109
143activation of Rac GTPase activity (GO:0032863)2.56820864
144regulation of early endosome to late endosome transport (GO:2000641)2.51177233
145regulation of NFAT protein import into nucleus (GO:0051532)2.49856685
146endothelial cell chemotaxis (GO:0035767)2.47596778
147regulation of apoptotic cell clearance (GO:2000425)2.47375827
148negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.44729541
149regulation of mammary gland epithelial cell proliferation (GO:0033599)2.43648542
150intracellular estrogen receptor signaling pathway (GO:0030520)2.41623211
151maternal placenta development (GO:0001893)2.40899046
152glucose 6-phosphate metabolic process (GO:0051156)2.40631253
153regulation of response to osmotic stress (GO:0047484)2.39643548
154atrioventricular valve morphogenesis (GO:0003181)2.39201925
155G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.38255005
156protein-lipid complex assembly (GO:0065005)2.36173257
157activation of JUN kinase activity (GO:0007257)2.35539078
158negative regulation of fatty acid transport (GO:2000192)2.34717775
159regulation of synapse maturation (GO:0090128)2.34454956
160cellular response to epidermal growth factor stimulus (GO:0071364)2.33152604
161epithelial cell-cell adhesion (GO:0090136)2.33098508
162histone H3-K9 demethylation (GO:0033169)2.32726908
163regulation of glucose import in response to insulin stimulus (GO:2001273)2.32674106
164negative regulation of myotube differentiation (GO:0010832)2.31645627
165signal complex assembly (GO:0007172)2.29761483
166modulation by virus of host morphology or physiology (GO:0019048)2.27835139
167mating behavior (GO:0007617)2.26891862
168synaptic vesicle exocytosis (GO:0016079)2.26158443
169plasma lipoprotein particle assembly (GO:0034377)2.25117112
170amino acid import (GO:0043090)2.23273163
1714-hydroxyproline metabolic process (GO:0019471)2.22715861
172positive regulation of extracellular matrix organization (GO:1903055)2.21417462
173activation of protein kinase A activity (GO:0034199)2.21106537
174cell-substrate junction assembly (GO:0007044)2.20563550
175positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.19019762
176neuronal ion channel clustering (GO:0045161)2.18687026
177positive regulation of histone deacetylation (GO:0031065)2.18630995
178stress fiber assembly (GO:0043149)2.18431587
179vitamin transmembrane transport (GO:0035461)2.17117063
180protein targeting to plasma membrane (GO:0072661)2.16727876
181response to laminar fluid shear stress (GO:0034616)2.16025060
182dopamine receptor signaling pathway (GO:0007212)2.15223179
183osteoblast development (GO:0002076)2.15052881
184barbed-end actin filament capping (GO:0051016)2.14663405
185regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.12642058
186positive regulation of protein dephosphorylation (GO:0035307)2.12127729
187activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.11692951
188activation of MAPKKK activity (GO:0000185)2.11495926
189establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.11243954
190mitochondrion transport along microtubule (GO:0047497)2.11243954
191diacylglycerol metabolic process (GO:0046339)2.10254762
192epithelial structure maintenance (GO:0010669)2.10053478
193embryonic process involved in female pregnancy (GO:0060136)2.09325905
194neuromuscular process controlling balance (GO:0050885)2.08188985

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.08006792
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.91752300
3TP63_17297297_ChIP-ChIP_HaCaT_Human2.86053026
4RXR_22158963_ChIP-Seq_LIVER_Mouse2.77120282
5PPARA_22158963_ChIP-Seq_LIVER_Mouse2.74997049
6LXR_22158963_ChIP-Seq_LIVER_Mouse2.47972391
7NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.43321792
8ZNF263_19887448_ChIP-Seq_K562_Human2.37562510
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.28404748
10EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.24784090
11KDM2B_26808549_Chip-Seq_SUP-B15_Human2.21355277
12LXR_22292898_ChIP-Seq_THP-1_Human2.21206114
13FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.17889316
14TBX20_22328084_ChIP-Seq_HEART_Mouse2.15234529
15TBX20_22080862_ChIP-Seq_HEART_Mouse2.15234529
16STAT6_21828071_ChIP-Seq_BEAS2B_Human2.11677697
17ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.05709362
18KDM2B_26808549_Chip-Seq_DND41_Human1.99309020
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.98009862
20ESR1_20079471_ChIP-ChIP_T-47D_Human1.88698632
21EZH2_22144423_ChIP-Seq_EOC_Human1.88093623
22DROSHA_22980978_ChIP-Seq_HELA_Human1.87392168
23ZFP281_18757296_ChIP-ChIP_E14_Mouse1.86994831
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.86567203
25EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.85736542
26KDM2B_26808549_Chip-Seq_K562_Human1.85720914
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.83992459
28TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.83155428
29EP300_21415370_ChIP-Seq_HL-1_Mouse1.81258583
30NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.77431725
31ESR2_21235772_ChIP-Seq_MCF-7_Human1.74169156
32SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.69047455
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.67511742
34NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.66799752
35CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.65555183
36EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.62863340
37TCF7_22412390_ChIP-Seq_EML_Mouse1.59056659
38RACK7_27058665_Chip-Seq_MCF-7_Human1.56025826
39CTCF_27219007_Chip-Seq_ERYTHROID_Human1.55161639
40CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.53120497
41CLOCK_20551151_ChIP-Seq_293T_Human1.51162341
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50180362
43KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.49575819
44DNAJC2_21179169_ChIP-ChIP_NT2_Human1.49439206
45RARB_27405468_Chip-Seq_BRAIN_Mouse1.47842407
46CTCF_27219007_Chip-Seq_Bcells_Human1.44698333
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.44180179
48CREB1_26743006_Chip-Seq_LNCaP_Human1.42298939
49KDM2B_26808549_Chip-Seq_JURKAT_Human1.42212149
50WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.40610180
51DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.39721890
52ZFP281_27345836_Chip-Seq_ESCs_Mouse1.38100775
53FOXA2_19822575_ChIP-Seq_HepG2_Human1.38077319
54PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.37233414
55SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.37103694
56SRY_22984422_ChIP-ChIP_TESTIS_Rat1.36925768
57MYC_22102868_ChIP-Seq_BL_Human1.36593146
58VDR_24763502_ChIP-Seq_THP-1_Human1.32807814
59KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.32692411
60RUNX1_27514584_Chip-Seq_MCF-7_Human1.29561188
61P68_20966046_ChIP-Seq_HELA_Human1.29210649
62E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.28578500
63NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.27031457
64ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.25879102
65ISL1_27105846_Chip-Seq_CPCs_Mouse1.25219723
66GATA1_19941826_ChIP-Seq_K562_Human1.23263670
67ESR1_21235772_ChIP-Seq_MCF-7_Human1.22131411
68TP63_22573176_ChIP-Seq_HFKS_Human1.21658015
69ERG_21242973_ChIP-ChIP_JURKAT_Human1.18691448
70KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18220661
71GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18130295
72TP53_22127205_ChIP-Seq_IMR90_Human1.17411497
73P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17109927
74VDR_21846776_ChIP-Seq_THP-1_Human1.16340382
75WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15977748
76NFIB_24661679_ChIP-Seq_LUNG_Mouse1.15841367
77SMC4_20622854_ChIP-Seq_HELA_Human1.14866365
78UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12611526
79MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.11318535
80VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10027561
81TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.09701476
82TET1_21490601_ChIP-Seq_MESCs_Mouse1.09551188
83GATA1_19941827_ChIP-Seq_MEL_Mouse1.08738478
84TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08111234
85SOX2_27498859_Chip-Seq_STOMACH_Mouse1.07501261
86EZH2_18974828_ChIP-Seq_MESCs_Mouse1.06533497
87RNF2_18974828_ChIP-Seq_MESCs_Mouse1.06533497
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.06020524
89SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06000436
90MAF_26560356_Chip-Seq_TH1_Human1.05908883
91UTX_26944678_Chip-Seq_JUKART_Human1.05650885
92TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.05484638
93NCOR1_26117541_ChIP-Seq_K562_Human1.05032933
94KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.04815553
95MTF2_20144788_ChIP-Seq_MESCs_Mouse1.04500799
96RARB_24833708_ChIP-Seq_LIVER_Mouse1.04461207
97EZH2_27294783_Chip-Seq_ESCs_Mouse1.04340948
98ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.03994287
99SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03631614
100RARA_24833708_ChIP-Seq_LIVER_Mouse1.01448752
101SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.01361007
102MAF_26560356_Chip-Seq_TH2_Human1.01163190
103TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.01081496
104SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.00771047
105SA1_27219007_Chip-Seq_ERYTHROID_Human0.99981988
106SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99695087
107TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.98461646
108OCT4_19829295_ChIP-Seq_ESCs_Human0.98394068
109RUNX1_22412390_ChIP-Seq_EML_Mouse0.98033307
110GATA1_22383799_ChIP-Seq_G1ME_Mouse0.96819044
111SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96381287
112DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.96374393
113CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.96335185
114ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.95723096
115SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.95574674
116PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95052340
117ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94557476
118CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.94448176
119TET1_21451524_ChIP-Seq_MESCs_Mouse0.94314441
120BCOR_27268052_Chip-Seq_Bcells_Human0.94081016
121SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.91947518
122RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.91878079
123BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91028384
124SPI1_23127762_ChIP-Seq_K562_Human0.89944174
125CTCF_21964334_ChIP-Seq_BJAB-B_Human0.89787646
126RING1B_27294783_Chip-Seq_ESCs_Mouse0.89460409
127KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.88982318
128SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.87557794
129CTNNB1_20460455_ChIP-Seq_HCT116_Human0.87448532
130ELF1_20517297_ChIP-Seq_JURKAT_Human0.87390574
131ATF3_27146783_Chip-Seq_COLON_Human0.87047540
132BCL6_27268052_Chip-Seq_Bcells_Human0.86716013

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.66150693
2MP0003646_muscle_fatigue4.23701559
3MP0004084_abnormal_cardiac_muscle4.22202829
4MP0000751_myopathy4.19702518
5MP0005058_abnormal_lysosome_morphology3.69497966
6MP0003172_abnormal_lysosome_physiology3.60202947
7MP0004215_abnormal_myocardial_fiber3.53963372
8MP0004036_abnormal_muscle_relaxation3.33876144
9MP0005409_darkened_coat_color3.10537666
10MP0005330_cardiomyopathy3.02582038
11MP0004130_abnormal_muscle_cell2.83596372
12MP0000749_muscle_degeneration2.79270183
13MP0004087_abnormal_muscle_fiber2.63367687
14MP0005360_urolithiasis2.55012418
15MP0008260_abnormal_autophagy2.52714253
16MP0003137_abnormal_impulse_conducting2.40900484
17MP0005451_abnormal_body_composition2.37716773
18MP0000566_synostosis2.34798013
19MP0002139_abnormal_hepatobiliary_system2.34437948
20MP0010630_abnormal_cardiac_muscle2.33744046
21MP0002249_abnormal_larynx_morphology2.32663673
22MP0002972_abnormal_cardiac_muscle2.27007415
23MP0008961_abnormal_basal_metabolism2.12060136
24MP0005620_abnormal_muscle_contractility2.11417145
25MP0002269_muscular_atrophy2.10924446
26MP0003283_abnormal_digestive_organ2.05496132
27MP0001544_abnormal_cardiovascular_syste2.03944595
28MP0005385_cardiovascular_system_phenoty2.03944595
29MP0005085_abnormal_gallbladder_physiolo2.03149331
30MP0008775_abnormal_heart_ventricle2.03059193
31MP0006138_congestive_heart_failure2.02962987
32MP0000678_abnormal_parathyroid_gland2.01107824
33MP0009278_abnormal_bone_marrow1.96058450
34MP0003705_abnormal_hypodermis_morpholog1.94876540
35MP0002234_abnormal_pharynx_morphology1.91041793
36MP0005670_abnormal_white_adipose1.86673338
37MP0003183_abnormal_peptide_metabolism1.86661002
38MP0005365_abnormal_bile_salt1.86332707
39MP0002106_abnormal_muscle_physiology1.81370865
40MP0005666_abnormal_adipose_tissue1.81368457
41MP0004085_abnormal_heartbeat1.78884621
42MP0004145_abnormal_muscle_electrophysio1.74721452
43MP0004233_abnormal_muscle_weight1.74598714
44MP0003123_paternal_imprinting1.69069735
45MP0002909_abnormal_adrenal_gland1.68603607
46MP0000750_abnormal_muscle_regeneration1.68340244
47MP0000747_muscle_weakness1.67525939
48MP0002822_catalepsy1.63904305
49MP0000759_abnormal_skeletal_muscle1.58947910
50MP0004264_abnormal_extraembryonic_tissu1.58634298
51MP0010329_abnormal_lipoprotein_level1.57503952
52MP0003690_abnormal_glial_cell1.56989118
53MP0004185_abnormal_adipocyte_glucose1.49727307
54MP0003252_abnormal_bile_duct1.46570468
55MP0004270_analgesia1.42908279
56MP0004484_altered_response_of1.41561073
57MP0005369_muscle_phenotype1.41207514
58MP0003122_maternal_imprinting1.40849941
59MP0003879_abnormal_hair_cell1.37991863
60MP0009780_abnormal_chondrocyte_physiolo1.37707408
61MP0003634_abnormal_glial_cell1.36766817
62MP0005083_abnormal_biliary_tract1.36754645
63MP0005423_abnormal_somatic_nervous1.34027416
64MP0005375_adipose_tissue_phenotype1.33612407
65MP0004043_abnormal_pH_regulation1.26025333
66MP0009840_abnormal_foam_cell1.25814767
67MP0002127_abnormal_cardiovascular_syste1.25477555
68MP0003828_pulmonary_edema1.24029911
69MP0003303_peritoneal_inflammation1.21079938
70MP0008875_abnormal_xenobiotic_pharmacok1.18805875
71MP0001666_abnormal_nutrient_absorption1.15737531
72MP0008569_lethality_at_weaning1.14489415
73MP0003635_abnormal_synaptic_transmissio1.13909602
74MP0006036_abnormal_mitochondrial_physio1.11617810
75MP0004381_abnormal_hair_follicle1.10391802
76MP0003091_abnormal_cell_migration1.09395630
77MP0001348_abnormal_lacrimal_gland1.08901543
78MP0000266_abnormal_heart_morphology1.08361468
79MP0002118_abnormal_lipid_homeostasis1.05451377
80MP0003221_abnormal_cardiomyocyte_apopto1.04656049
81MP0000920_abnormal_myelination1.04318751
82MP0001958_emphysema1.02861086
83MP0010368_abnormal_lymphatic_system1.01281350
84MP0005377_hearing/vestibular/ear_phenot1.00498684
85MP0003878_abnormal_ear_physiology1.00498684
86MP0003436_decreased_susceptibility_to1.00404302
87MP0003453_abnormal_keratinocyte_physiol0.99951223
88MP0004510_myositis0.99774579
89MP0001502_abnormal_circadian_rhythm0.98621289
90MP0000681_abnormal_thyroid_gland0.94664704
91MP0004858_abnormal_nervous_system0.93260439
92MP0005167_abnormal_blood-brain_barrier0.92960960
93MP0000003_abnormal_adipose_tissue0.91521499
94MP0001270_distended_abdomen0.91259186
95MP0003806_abnormal_nucleotide_metabolis0.91051466
96MP0005257_abnormal_intraocular_pressure0.90385162
97MP0005332_abnormal_amino_acid0.90280087
98MP0002896_abnormal_bone_mineralization0.89252104
99MP0005319_abnormal_enzyme/_coenzyme0.88815628
100MP0000604_amyloidosis0.87789426
101MP0005076_abnormal_cell_differentiation0.86416215
102MP0000858_altered_metastatic_potential0.86186871
103MP0002063_abnormal_learning/memory/cond0.84972976
104MP0009384_cardiac_valve_regurgitation0.84939551
105MP0000537_abnormal_urethra_morphology0.83954340
106MP0008874_decreased_physiological_sensi0.83575243
107MP0003300_gastrointestinal_ulcer0.81729490
108MP0005187_abnormal_penis_morphology0.81178651
109MP0002078_abnormal_glucose_homeostasis0.79979560
110MP0004859_abnormal_synaptic_plasticity0.78752661
111MP0003567_abnormal_fetal_cardiomyocyte0.78484830
112MP0000467_abnormal_esophagus_morphology0.78377158
113MP0000462_abnormal_digestive_system0.78007893
114MP0010234_abnormal_vibrissa_follicle0.77366493
115MP0002332_abnormal_exercise_endurance0.77286515
116MP0001915_intracranial_hemorrhage0.76170234
117MP0000609_abnormal_liver_physiology0.75928576
118MP0002653_abnormal_ependyma_morphology0.74521502
119MP0005266_abnormal_metabolism0.73412562
120MP0002971_abnormal_brown_adipose0.71578981
121MP0000534_abnormal_ureter_morphology0.71347657
122MP0003115_abnormal_respiratory_system0.70725374
123MP0003942_abnormal_urinary_system0.70418047
124MP0002128_abnormal_blood_circulation0.70370023
125MP0003329_amyloid_beta_deposits0.70353769
126MP0000230_abnormal_systemic_arterial0.70240489
127MP0002998_abnormal_bone_remodeling0.69781771
128MP0005584_abnormal_enzyme/coenzyme_acti0.69497862
129MP0002132_abnormal_respiratory_system0.68522656
130MP0003566_abnormal_cell_adhesion0.68471851
131MP0000733_abnormal_muscle_development0.67065477
132MP0003948_abnormal_gas_homeostasis0.67041346
133MP0004947_skin_inflammation0.66787406
134MP0003075_altered_response_to0.66785677
135MP0009643_abnormal_urine_homeostasis0.66706946
136MP0002116_abnormal_craniofacial_bone0.65298633
137MP0002064_seizures0.63961940
138MP0005623_abnormal_meninges_morphology0.63701655
139MP0003632_abnormal_nervous_system0.62870368
140MP0002396_abnormal_hematopoietic_system0.62638877
141MP0003938_abnormal_ear_development0.61574173
142MP0003279_aneurysm0.60656074
143MP0002932_abnormal_joint_morphology0.60619446
144MP0003191_abnormal_cellular_cholesterol0.58223496
145MP0004272_abnormal_basement_membrane0.58197561
146MP0001765_abnormal_ion_homeostasis0.56562353
147MP0002108_abnormal_muscle_morphology0.55154011
148MP0000013_abnormal_adipose_tissue0.54785628
149MP0002925_abnormal_cardiovascular_devel0.54448565
150MP0002089_abnormal_postnatal_growth/wei0.54442387
151MP0009672_abnormal_birth_weight0.53302830
152MP0009053_abnormal_anal_canal0.52807479
153MP0001849_ear_inflammation0.51974594
154MP0003119_abnormal_digestive_system0.51333589
155MP0000767_abnormal_smooth_muscle0.50419788
156MP0005334_abnormal_fat_pad0.48854333

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.52399010
2Exercise-induced myalgia (HP:0003738)5.36001115
3Ventricular tachycardia (HP:0004756)5.20959767
4Exercise-induced muscle cramps (HP:0003710)4.73779745
5Myoglobinuria (HP:0002913)4.55692920
6Right ventricular cardiomyopathy (HP:0011663)4.33834764
7Atrial fibrillation (HP:0005110)4.32101905
8Calf muscle hypertrophy (HP:0008981)4.27047030
9Hyporeflexia of lower limbs (HP:0002600)4.22312045
10Primary atrial arrhythmia (HP:0001692)4.08835839
11Bundle branch block (HP:0011710)3.96583926
12Syncope (HP:0001279)3.96153144
13Supraventricular tachycardia (HP:0004755)3.90085180
14Muscle hypertrophy of the lower extremities (HP:0008968)3.90011753
15Supraventricular arrhythmia (HP:0005115)3.85122581
16Muscle fiber splitting (HP:0003555)3.83611367
17Subaortic stenosis (HP:0001682)3.81159952
18Abnormality of the left ventricular outflow tract (HP:0011103)3.81159952
19Obstructive sleep apnea (HP:0002870)3.80002433
20Difficulty running (HP:0009046)3.78037725
21Prolonged QT interval (HP:0001657)3.64900700
22Asymmetric septal hypertrophy (HP:0001670)3.64231822
23Lipoatrophy (HP:0100578)3.63779708
24Abnormality of the calf musculature (HP:0001430)3.61430210
25Ketoacidosis (HP:0001993)3.57555155
26Ventricular fibrillation (HP:0001663)3.52481361
27Atrioventricular block (HP:0001678)3.49544201
28Ventricular arrhythmia (HP:0004308)3.42282216
29Heart block (HP:0012722)3.41686071
30Palpitations (HP:0001962)3.36246052
31Increased connective tissue (HP:0009025)3.24219243
32Ketosis (HP:0001946)3.19082244
33Abnormal atrioventricular conduction (HP:0005150)3.16012634
34Dilated cardiomyopathy (HP:0001644)3.15764829
35Hypoglycemic coma (HP:0001325)3.04813629
36Flat acetabular roof (HP:0003180)2.95798556
37Rhabdomyolysis (HP:0003201)2.95067381
38EMG: myopathic abnormalities (HP:0003458)2.93740258
39Dysmetric saccades (HP:0000641)2.93444244
40Broad face (HP:0000283)2.91275669
41Lymphangioma (HP:0100764)2.81446671
42Hemorrhage of the eye (HP:0011885)2.79608339
43Abnormal EKG (HP:0003115)2.67354997
44Supranuclear gaze palsy (HP:0000605)2.67052939
45Bronchomalacia (HP:0002780)2.66190342
46Myopathic facies (HP:0002058)2.62061226
47Myotonia (HP:0002486)2.54632471
48Hyperglycinuria (HP:0003108)2.53170705
49Neurofibrillary tangles (HP:0002185)2.52910581
50Deep venous thrombosis (HP:0002625)2.49347386
51Protrusio acetabuli (HP:0003179)2.47534818
52Stridor (HP:0010307)2.46570736
53Ankle clonus (HP:0011448)2.45612355
54Hyperinsulinemic hypoglycemia (HP:0000825)2.45501357
55Hyperammonemia (HP:0001987)2.42175434
56Difficulty climbing stairs (HP:0003551)2.41836555
57Thin bony cortex (HP:0002753)2.40761494
58Centrally nucleated skeletal muscle fibers (HP:0003687)2.37774952
59Hamartoma of the eye (HP:0010568)2.35252722
60Abnormality of fatty-acid metabolism (HP:0004359)2.34155981
61Increased variability in muscle fiber diameter (HP:0003557)2.30806209
62Dysostosis multiplex (HP:0000943)2.30055180
63Large for gestational age (HP:0001520)2.29484580
64Ulnar bowing (HP:0003031)2.28627954
65EMG: neuropathic changes (HP:0003445)2.28305855
66Urinary glycosaminoglycan excretion (HP:0003541)2.25145331
67Mucopolysacchariduria (HP:0008155)2.25145331
68Mildly elevated creatine phosphokinase (HP:0008180)2.24116125
69J-shaped sella turcica (HP:0002680)2.22976748
70Cerebral inclusion bodies (HP:0100314)2.21620170
71Gout (HP:0001997)2.20850861
72Abnormality of the thoracic spine (HP:0100711)2.20024988
73Cervical subluxation (HP:0003308)2.19808936
74Turricephaly (HP:0000262)2.19056460
75Metaphyseal cupping (HP:0003021)2.17759834
76Asymmetry of the thorax (HP:0001555)2.17634309
77Insomnia (HP:0100785)2.16439096
78Atelectasis (HP:0100750)2.14962319
79Neuronal loss in central nervous system (HP:0002529)2.13807694
80Late onset (HP:0003584)2.13709349
81Abnormality of dicarboxylic acid metabolism (HP:0010995)2.13403025
82Dicarboxylic aciduria (HP:0003215)2.13403025
83Muscle stiffness (HP:0003552)2.12065628
84Distal lower limb muscle weakness (HP:0009053)2.11763453
85Abnormality of glycine metabolism (HP:0010895)2.11220673
86Abnormality of serine family amino acid metabolism (HP:0010894)2.11220673
87Broad metatarsal (HP:0001783)2.10670455
88Shallow orbits (HP:0000586)2.10666580
89Cholelithiasis (HP:0001081)2.10560985
90Broad palm (HP:0001169)2.09241408
91Abnormality of mucopolysaccharide metabolism (HP:0011020)2.08933417
92Abnormality of polysaccharide metabolism (HP:0011012)2.08933417
93Abnormality of glycosaminoglycan metabolism (HP:0004371)2.08933417
94Limb-girdle muscle atrophy (HP:0003797)2.08604103
95Annular pancreas (HP:0001734)2.08307581
96Pancreatic islet-cell hyperplasia (HP:0004510)2.07807327
97Nuclear cataract (HP:0100018)2.06576527
98Pointed chin (HP:0000307)2.05193402
99Athetosis (HP:0002305)2.02770963
100Germ cell neoplasia (HP:0100728)2.01642940
101Polycythemia (HP:0001901)2.01628201
102Sudden cardiac death (HP:0001645)2.00855290
103Hyperacusis (HP:0010780)2.00382909
104Cerebral aneurysm (HP:0004944)1.99109788
105Type 1 muscle fiber predominance (HP:0003803)1.96916961
106Mitral regurgitation (HP:0001653)1.96563076
107Hypercortisolism (HP:0001578)1.96156753
108Abnormality of skeletal muscle fiber size (HP:0012084)1.95971868
109Ragged-red muscle fibers (HP:0003200)1.95823613
110Thin ribs (HP:0000883)1.95799438
111Disproportionate tall stature (HP:0001519)1.94552859
112Abnormality of the fingertips (HP:0001211)1.91904516
113Bowel incontinence (HP:0002607)1.90337580
114Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.90223711
115Aneurysm (HP:0002617)1.88368336
116Left ventricular hypertrophy (HP:0001712)1.87974129
117Xanthomatosis (HP:0000991)1.87591777
118Thoracic kyphosis (HP:0002942)1.85989136
119Abnormal gallbladder morphology (HP:0012437)1.84941758
120Easy fatigability (HP:0003388)1.84395596
121Visceral angiomatosis (HP:0100761)1.83199123
122Neoplasm of the heart (HP:0100544)1.81507032
123Diaphragmatic weakness (HP:0009113)1.80941773
124Abnormality of endocrine pancreas physiology (HP:0012093)1.80567413
125Abnormality of the pancreatic islet cells (HP:0006476)1.80567413
126Abnormality of the lower motor neuron (HP:0002366)1.78007761
127Testicular atrophy (HP:0000029)1.77349278
128Hand muscle atrophy (HP:0009130)1.77182419
129Lower limb amyotrophy (HP:0007210)1.76961816
130Conjunctival hamartoma (HP:0100780)1.76147523
131Intrahepatic cholestasis (HP:0001406)1.74990627
132Abnormal gallbladder physiology (HP:0012438)1.74911565
133Cholecystitis (HP:0001082)1.74911565
134Abnormality of the aortic arch (HP:0012303)1.74511638
135Peripheral hypomyelination (HP:0007182)1.74317320
136Hypoalphalipoproteinemia (HP:0003233)1.73797999
137Bulbar palsy (HP:0001283)1.73315961
138Skin nodule (HP:0200036)1.73125758
139Vertebral compression fractures (HP:0002953)1.73120617
140Growth hormone excess (HP:0000845)1.71811053
141Distal lower limb amyotrophy (HP:0008944)1.70648951
142Abnormal large intestine physiology (HP:0012700)1.70640089
143Cupped ribs (HP:0000887)1.69751379
144Palmoplantar keratoderma (HP:0000982)1.69172471
145Supernumerary nipples (HP:0002558)1.68988797
146Precocious puberty (HP:0000826)1.68424151
147Hemangiomatosis (HP:0007461)1.67612517
148Abnormality of the periventricular white matter (HP:0002518)1.67573664
149Spinal canal stenosis (HP:0003416)1.66718157
150Elfin facies (HP:0004428)1.66510074
151Metabolic acidosis (HP:0001942)1.66109635
152Long toe (HP:0010511)1.65929248
153Neonatal death (HP:0003811)1.65723533
154Biconcave vertebral bodies (HP:0004586)1.65691251
155Lower limb asymmetry (HP:0100559)1.65100935
156Arnold-Chiari malformation (HP:0002308)1.64064240
157Abnormality of the distal phalanx of the thumb (HP:0009617)1.64061003
158Hypercholesterolemia (HP:0003124)1.62345261
159Congestive heart failure (HP:0001635)1.61542206
160Achilles tendon contracture (HP:0001771)1.60473265
161Abnormal vertebral ossification (HP:0100569)1.60311064
162Neonatal onset (HP:0003623)1.59443056
163Distal upper limb amyotrophy (HP:0007149)1.59373000
164Upper limb amyotrophy (HP:0009129)1.59373000
165Polygenic inheritance (HP:0010982)1.58987554
166Bell-shaped thorax (HP:0001591)1.58866309
167Reticulocytosis (HP:0001923)1.57697336
168Rapidly progressive (HP:0003678)1.57529545
169Abnormality of the Achilles tendon (HP:0005109)1.56991526
170Mask-like facies (HP:0000298)1.56517604
171Vertebral arch anomaly (HP:0008438)1.56494479
172Deformed sella turcica (HP:0002681)1.56241354
173Abnormality of carpal bone ossification (HP:0006257)1.56088260
174Advanced eruption of teeth (HP:0006288)1.55482147
175Macroorchidism (HP:0000053)1.55358326
176Premature skin wrinkling (HP:0100678)1.55185370
177Abnormal ossification of hand bones (HP:0005921)1.54502953

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.27141315
2TTN3.59731329
3PKN23.46801988
4PRPF4B2.81634010
5LMTK22.79069241
6PHKG12.78877209
7PHKG22.78877209
8MAP3K102.69369267
9ICK2.56373522
10SMG12.53619653
11SIK12.35819372
12DMPK2.34342338
13RIPK12.19842584
14BCKDK1.93995866
15ERN11.91506190
16EPHB21.81137776
17OBSCN1.78918522
18PDK41.78800343
19PDK31.78800343
20EEF2K1.70513802
21PDGFRA1.66144912
22MYLK1.62325339
23MAP3K71.61585563
24NEK11.61550520
25PTK61.56160952
26PRKD31.51091703
27EPHA21.36671090
28MST1R1.32987108
29CDK191.29592674
30TNK21.28759650
31NTRK31.17762910
32INSRR1.16181271
33WNK41.14345260
34FGFR41.13539564
35KSR11.13074473
36FGFR31.10799682
37MATK1.08878086
38TIE11.08530645
39CDC42BPA1.08164493
40CAMK1G1.07801524
41TYRO31.06843190
42EPHB11.05243445
43DAPK21.05170351
44STK381.05165681
45MAP3K131.05039953
46PAK31.02737867
47PRKD10.97467932
48PRKAA10.96471074
49MAPK150.95722489
50RIPK40.89394959
51CAMK1D0.86763436
52MTOR0.86220855
53MAP3K110.85434216
54KSR20.83519588
55MAP4K10.83015797
56MAP3K60.82019190
57PRKAA20.80843509
58FLT30.79820898
59CAMK40.79577925
60PAK60.78505413
61MAP2K40.78462156
62CDK120.78020106
63FGFR20.77472868
64TAOK10.76241486
65RET0.75836944
66DYRK1B0.74433719
67MAPK120.69753572
68TESK10.69487692
69DDR20.68776472
70ERBB20.68095958
71PINK10.68036152
72ROCK10.66170065
73MAP2K30.65885021
74HIPK20.65781154
75NTRK20.64225882
76PRKCH0.63036519
77STK110.62764940
78TAOK20.62685152
79TGFBR20.62176698
80WNK10.61769941
81CAMKK10.61575026
82ILK0.61336706
83MAPKAPK30.60685948
84NME10.60291755
85SGK30.60088930
86NTRK10.59913411
87MAP2K60.59865336
88EPHA40.59807873
89STK40.58916078
90PDK20.58791555
91MARK20.58420148
92PTK2B0.57777936
93SIK20.57659129
94LATS20.57267581
95DAPK30.57106708
96LRRK20.56856976
97CDK150.56794191
98CDK11A0.55960739
99MAPK100.54377360
100IRAK30.53957677
101MAPK70.53586774
102ZAP700.53021571
103STK240.52933465
104MAP3K10.52502542
105MAP2K20.52489126
106TYK20.52015217
107NEK60.51936420
108PDPK10.51513684
109MAPK110.51431693
110UHMK10.50417471
111MAP3K30.50053210
112MET0.48958074
113RPS6KA20.48540554
114CDK180.48492169
115PDGFRB0.47064552
116PAK40.46460900
117RPS6KC10.46336010
118RPS6KL10.46336010
119PRKG20.45509215
120RPS6KA10.45469162
121PRKD20.45139552
122PRKACG0.44249870
123PRKCI0.44079544
124PTK20.43610212
125JAK20.43451574
126BMX0.43128203
127SGK4940.42922395
128SGK2230.42922395
129MAPK80.42716229
130GRK60.42464866
131CAMK10.42134141
132TBK10.41911266
133AKT20.41771556
134CDK50.40658826
135PDK10.40069393
136ALK0.39168153
137ROCK20.38501227
138ARAF0.38417119
139PIK3CA0.37559325
140RPS6KA60.36506494
141KDR0.35791783
142CAMK2D0.35462407
143SIK30.34928500
144RPS6KA30.34129420

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.62548741
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.40913015
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.38263660
4Other glycan degradation_Homo sapiens_hsa005113.00335732
5Fatty acid degradation_Homo sapiens_hsa000712.85675506
6Propanoate metabolism_Homo sapiens_hsa006402.51102808
7Nitrogen metabolism_Homo sapiens_hsa009102.37171975
8Fatty acid metabolism_Homo sapiens_hsa012122.24353721
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.12761962
10Dilated cardiomyopathy_Homo sapiens_hsa054142.04516610
11Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.99751726
12Arginine biosynthesis_Homo sapiens_hsa002201.93564108
13Glycosaminoglycan degradation_Homo sapiens_hsa005311.92199561
14Cardiac muscle contraction_Homo sapiens_hsa042601.90813018
15Carbon metabolism_Homo sapiens_hsa012001.89749274
16Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.86428872
17Butanoate metabolism_Homo sapiens_hsa006501.80335164
18PPAR signaling pathway_Homo sapiens_hsa033201.68275505
19Tryptophan metabolism_Homo sapiens_hsa003801.63316889
20Lysine degradation_Homo sapiens_hsa003101.62974102
21Pyruvate metabolism_Homo sapiens_hsa006201.56168104
22Acute myeloid leukemia_Homo sapiens_hsa052211.52447287
23Bile secretion_Homo sapiens_hsa049761.48505790
24Chronic myeloid leukemia_Homo sapiens_hsa052201.47469460
25Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.46440048
26Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.40821401
27Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.38960936
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.37986843
29Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.35745684
30Phospholipase D signaling pathway_Homo sapiens_hsa040721.34736449
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.33396281
32ErbB signaling pathway_Homo sapiens_hsa040121.32849881
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.30369149
34Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.28614965
35Phosphatidylinositol signaling system_Homo sapiens_hsa040701.28434689
36Insulin resistance_Homo sapiens_hsa049311.28142490
37Choline metabolism in cancer_Homo sapiens_hsa052311.28132247
38Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.24811725
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.23153488
40Biosynthesis of amino acids_Homo sapiens_hsa012301.20299869
41Starch and sucrose metabolism_Homo sapiens_hsa005001.18250072
42Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16213346
43beta-Alanine metabolism_Homo sapiens_hsa004101.14194685
44Fatty acid biosynthesis_Homo sapiens_hsa000611.14171341
45Glucagon signaling pathway_Homo sapiens_hsa049221.13751330
46Long-term potentiation_Homo sapiens_hsa047201.13712724
47Cocaine addiction_Homo sapiens_hsa050301.13446988
48Prion diseases_Homo sapiens_hsa050201.10262205
49Adipocytokine signaling pathway_Homo sapiens_hsa049201.06961826
50Inositol phosphate metabolism_Homo sapiens_hsa005621.05552795
51Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05416830
52Type II diabetes mellitus_Homo sapiens_hsa049301.05105810
53Insulin signaling pathway_Homo sapiens_hsa049101.00793536
54Pancreatic cancer_Homo sapiens_hsa052120.99069353
55Pentose phosphate pathway_Homo sapiens_hsa000300.98593710
56Fat digestion and absorption_Homo sapiens_hsa049750.98118741
57Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.94853874
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92170683
59AMPK signaling pathway_Homo sapiens_hsa041520.91858727
60Histidine metabolism_Homo sapiens_hsa003400.90152636
61Amphetamine addiction_Homo sapiens_hsa050310.89638306
62Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.88888968
63Bladder cancer_Homo sapiens_hsa052190.87711422
64ABC transporters_Homo sapiens_hsa020100.86114974
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.85116884
66Renal cell carcinoma_Homo sapiens_hsa052110.84315898
67Synaptic vesicle cycle_Homo sapiens_hsa047210.83077231
68B cell receptor signaling pathway_Homo sapiens_hsa046620.82923863
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.82190910
70Insulin secretion_Homo sapiens_hsa049110.80938650
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80899861
72Axon guidance_Homo sapiens_hsa043600.80438244
73Prolactin signaling pathway_Homo sapiens_hsa049170.80128854
74Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.78893286
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.78585571
76Notch signaling pathway_Homo sapiens_hsa043300.78308298
77Aldosterone synthesis and secretion_Homo sapiens_hsa049250.77910020
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.77721518
79Gastric acid secretion_Homo sapiens_hsa049710.77229505
80Peroxisome_Homo sapiens_hsa041460.76411580
81Central carbon metabolism in cancer_Homo sapiens_hsa052300.75781876
82Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.74280458
83Dorso-ventral axis formation_Homo sapiens_hsa043200.72804809
84Leukocyte transendothelial migration_Homo sapiens_hsa046700.72419292
85Viral myocarditis_Homo sapiens_hsa054160.70558045
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70526394
87Lysosome_Homo sapiens_hsa041420.69815455
88Carbohydrate digestion and absorption_Homo sapiens_hsa049730.68876981
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68876654
90Endocytosis_Homo sapiens_hsa041440.67219471
91Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66195296
92Galactose metabolism_Homo sapiens_hsa000520.65699718
93Glycerolipid metabolism_Homo sapiens_hsa005610.64633623
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.64150247
95Amoebiasis_Homo sapiens_hsa051460.63661599
96HIF-1 signaling pathway_Homo sapiens_hsa040660.63080264
97Phenylalanine metabolism_Homo sapiens_hsa003600.62974424
98Hepatitis C_Homo sapiens_hsa051600.61595773
99Prostate cancer_Homo sapiens_hsa052150.61456205
100Rap1 signaling pathway_Homo sapiens_hsa040150.60117635
101ECM-receptor interaction_Homo sapiens_hsa045120.59216970
102Thyroid cancer_Homo sapiens_hsa052160.58878923
103mTOR signaling pathway_Homo sapiens_hsa041500.58153191
104Vibrio cholerae infection_Homo sapiens_hsa051100.57682617
105Oxytocin signaling pathway_Homo sapiens_hsa049210.56292916
106Fructose and mannose metabolism_Homo sapiens_hsa000510.56204723
107Olfactory transduction_Homo sapiens_hsa047400.56014485
108Colorectal cancer_Homo sapiens_hsa052100.55454876
109Arginine and proline metabolism_Homo sapiens_hsa003300.54900683
110Tyrosine metabolism_Homo sapiens_hsa003500.54240109
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.54197715
112Fatty acid elongation_Homo sapiens_hsa000620.53986375
113Dopaminergic synapse_Homo sapiens_hsa047280.52900764
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.52332263
115Renin secretion_Homo sapiens_hsa049240.51564890
116Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50611135
117Circadian entrainment_Homo sapiens_hsa047130.50357290
118Focal adhesion_Homo sapiens_hsa045100.50286650
119Complement and coagulation cascades_Homo sapiens_hsa046100.49896885
120Cyanoamino acid metabolism_Homo sapiens_hsa004600.48893868
121Basal cell carcinoma_Homo sapiens_hsa052170.48154163
122Selenocompound metabolism_Homo sapiens_hsa004500.47502339
123Calcium signaling pathway_Homo sapiens_hsa040200.46766847
124Sulfur metabolism_Homo sapiens_hsa009200.46572603
125Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44808509
126Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.44482843
127Estrogen signaling pathway_Homo sapiens_hsa049150.43557237
128cAMP signaling pathway_Homo sapiens_hsa040240.42485910
129VEGF signaling pathway_Homo sapiens_hsa043700.42304631
130Adherens junction_Homo sapiens_hsa045200.39787005
131Salivary secretion_Homo sapiens_hsa049700.38893356
132Vascular smooth muscle contraction_Homo sapiens_hsa042700.38581275
133Tight junction_Homo sapiens_hsa045300.38078919
134Caffeine metabolism_Homo sapiens_hsa002320.38044621
135Non-small cell lung cancer_Homo sapiens_hsa052230.36746466
136Endometrial cancer_Homo sapiens_hsa052130.35619814
137Glioma_Homo sapiens_hsa052140.34790410
138Melanogenesis_Homo sapiens_hsa049160.34470691
139Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.33292526
140Proteoglycans in cancer_Homo sapiens_hsa052050.33003431
141GnRH signaling pathway_Homo sapiens_hsa049120.31503632
142Sulfur relay system_Homo sapiens_hsa041220.31338740
143Cholinergic synapse_Homo sapiens_hsa047250.29006276
144Gap junction_Homo sapiens_hsa045400.28768256
145Pancreatic secretion_Homo sapiens_hsa049720.28090976
146Thyroid hormone synthesis_Homo sapiens_hsa049180.27367855

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